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Somnolence

Endpoint Browser

R18_SOMNOLENCE

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — R40.0
  • Cause of death: ICD-10 — R40.0

2 out of 7 registries used, show all original rules.

478

4. Check minimum number of events

None

478

5. Include endpoints

None

478

6. Filter based on genotype QC (FinnGen only)

478

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 478 279 199
Unadjusted period prevalence (%) 0.09 0.10 0.09
Median age at first event (years) 49.15 42.42 58.58

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
432
Matched controls
4320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R40.0
ICD-10 Finland
Somnolence
+∞
323.0
432
*
R53
ICD-10 Finland
Malaise and fatigue
4.9
43.8
182
562
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
7.6
31.1
77
120
AA1AD
NOMESCO Finland
CT of head and brain
4.0
30.9
153
525
N05AH04
ATC
quetiapine; oral
4.0
28.3
134
437
N06AX16
ATC
venlafaxine; oral
4.3
27.9
119
352
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.2
27.2
117
348
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
6.0
25.1
73
141
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.0
24.8
64
105
N03AG01
ATC
valproic acid; systemic, rectal
6.5
24.2
66
117
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.3
22.2
91
254
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.6
22.1
59
101
N03AX16
ATC
pregabalin; oral
3.1
20.1
131
527
R51.80
ICD-10 Finland
Headache
3.4
19.7
111
402
G47.1
ICD-10 Finland
Disorders of excessive somnolence [hypersomnias]
73.2
18.9
21
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
7.4
18.6
45
67
G47.9
ICD-10 Finland
Sleep disorder, unspecified
10.8
18.3
35
35
R42
ICD-10 Finland
Dizziness and giddiness
3.0
17.8
119
482
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
5.3
17.6
56
119
N06AB04
ATC
citalopram; systemic
2.8
17.5
136
606
N06AX12
ATC
bupropion; oral
4.5
17.4
65
164
N05BA01
ATC
diazepam; systemic, rectal
3.4
17.0
91
313
N06AX21
ATC
duloxetine; oral
3.8
16.9
78
239
TAB00
NOMESCO Finland
Lumbar puncture
6.3
16.7
45
78
R55
ICD-10 Finland
Syncope and collapse
3.8
16.6
74
220
N03AE01
ATC
clonazepam; systemic
5.2
16.4
52
110
G47.3
ICD-10 Finland
Sleep apnoea
2.9
16.2
116
487
XA800
NOMESCO Finland
Neuropsychological investigation
6.8
16.1
41
66
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.2
15.9
64
173
G47.4
ICD-10 Finland
Narcolepsy and cataplexy
62.4
15.9
18
*
A06AD11
ATC
lactulose; oral
3.3
15.8
86
299
N05AA02
ATC
levomepromazine; systemic
6.3
15.6
42
73
N05AH03
ATC
olanzapine; systemic
4.6
15.2
54
129
N03AX09
ATC
lamotrigine; oral
5.2
15.2
48
101
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.4
14.8
39
66
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
14.7
85
308
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
14.7
182
1026
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.1
14.5
59
161
N06AA09
ATC
amitriptyline; systemic
3.7
14.5
66
199
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.3
14.5
56
146
N05BA04
ATC
oxazepam; oral
2.5
14.1
133
650
N06AB03
ATC
fluoxetine; oral
3.2
13.9
81
294
S06.0
ICD-10 Finland
Concussion
3.4
13.9
71
235
C07AB07
ATC
bisoprolol; oral
2.2
13.9
198
1185
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
13.7
137
688
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
13.7
82
304
G47.2
ICD-10 Finland
Disorders of the sleep-wake schedule
35.3
13.6
17
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
13.4
121
577
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.1
13.2
53
143
N04BC05
ATC
pramipexole; oral
4.4
13.0
48
120
N05AX08
ATC
risperidone; systemic
3.6
12.8
60
185
N05CF01
ATC
zopiclone; oral
2.3
12.8
153
837
A04
ICPC
Weakness/tiredness general
2.9
12.7
86
345
N06AB10
ATC
escitalopram; oral
2.5
12.6
119
578
N06AX11
ATC
mirtazapine; oral
2.3
12.6
157
873
N03AX12
ATC
gabapentin; oral
2.9
12.6
85
338
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.6
12.4
59
184
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
12.4
182
1091
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.6
12.3
101
453
N06AB06
ATC
sertraline; oral
3.0
12.3
75
281
M79.6
ICD-10 Finland
Pain in limb
2.2
12.2
164
941
N06BA07
ATC
modafinil; oral
27.6
12.1
16
6
N39.4
ICD-10 Finland
Other specified urinary incontinence
4.2
12.1
47
123
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.3
12.1
45
113
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.3
12.1
64
217
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.5
11.9
58
185
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.1
11.9
70
254
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.3
11.7
43
107
N05AD01
ATC
haloperidol; systemic
6.4
11.3
29
48
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
11.2
71
272
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.6
11.1
92
414
S18
ICPC
Laceration/cut
2.1
11.1
172
1043
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
10.9
102
488
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
7.9
10.8
24
32
R06.0
ICD-10 Finland
Dyspnoea
2.3
10.8
112
566
N05CD07
ATC
temazepam; oral
2.9
10.7
68
259
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.7
10.6
30
56
N03AX11
ATC
topiramate; oral
6.5
10.6
27
44
F34.1
ICD-10 Finland
Dysthymia
5.1
10.6
33
69
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
10.6
84
368
F10.09
ICD-10 Finland
Alcohol intoxication UNS
7.1
10.5
25
37
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.0
10.4
42
114
N05AX12
ATC
aripiprazole; systemic
4.5
10.4
36
85
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
10.3
136
762
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.6
10.3
47
142
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
4.2
10.3
39
100
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
10.3
115
600
R41.0
ICD-10 Finland
Disorientation, unspecified
6.2
10.3
27
46
G43.9
ICD-10 Finland
Migraine, unspecified
3.7
10.2
45
133
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
15.0
10.1
16
11
N02AX02
ATC
tramadol; systemic, rectal
2.0
10.0
179
1136
C03CA01
ATC
furosemide; systemic
2.2
10.0
122
662
A02BC02
ATC
pantoprazole; systemic
1.9
9.9
261
1909
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.5
9.9
80
355
N05AB03
ATC
perphenazine; systemic, rectal
5.1
9.8
30
62
R4110
NOMESCO Finland
Physiotherapy
2.2
9.8
120
649
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.8
9.7
63
245
A28
ICPC
Limited function/disability NOS
2.7
9.7
72
302
R50.9
ICD-10 Finland
Fever, unspecified
2.5
9.6
81
366
Z71.8
ICD-10 Finland
Other specified counselling
2.2
9.6
119
647
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
9.6
117
632
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
6.9
9.6
23
35
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
5.6
9.5
27
51
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
9.5
87
412
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
9.4
97
486
H02AB06
ATC
prednisolone; systemic
1.9
9.3
196
1308
N05AF03
ATC
chlorprothixene; systemic
5.2
9.3
28
57
G44.2
ICD-10 Finland
Tension-type headache
2.6
9.3
71
305
L28
ICPC
Limited function/disability (L)
2.6
9.2
69
290
N05AF05
ATC
zuclopenthixol; systemic
16.0
9.1
14
9
WX892
NOMESCO Finland
Monitored bed care
3.3
9.1
45
146
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
5.0
9.0
28
59
M25.5
ICD-10 Finland
Pain in joint
2.1
9.0
120
671
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
8.9
47
160
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.1
8.9
49
169
N06AX18
ATC
reboxetine; oral
9.8
8.8
17
18
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.1
8.8
109
590
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
8.8
114
629
R06.5
ICD-10 Finland
Mouth breathing
3.1
8.7
47
162
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
8.7
67
287
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.9
8.7
53
197
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
5.2
8.7
26
53
P76
ICPC
Depressive disorder
3.1
8.5
48
169
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
8.5
66
284
G41.9
ICD-10 Finland
Status epilepticus, unspecified
20.5
8.5
12
6
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.2
8.5
25
50
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
8.5
192
1303
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.2
8.4
31
78
R40
ICD-10 Finland
Somnolence, stupor and coma
91.8
8.4
9
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
8.4
53
202
A02BC05
ATC
esomeprazole; systemic
1.9
8.4
159
1012
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.4
8.4
78
370
N05CF02
ATC
zolpidem; oral
2.3
8.4
82
399
L17
ICPC
Foot/toe symptom/complaint
2.1
8.3
107
588
N30.0
ICD-10 Finland
Acute cystitis
2.4
8.3
70
317
N06AA12
ATC
doxepin; systemic
4.0
8.2
32
85
N07BB01
ATC
disulfiram; oral
4.0
8.2
32
85
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
8.2
103
559
A46
ICD-10 Finland
Erysipelas
2.5
8.2
66
288
E86
ICD-10 Finland
Volume depletion
7.0
8.2
19
28
N06AB05
ATC
paroxetine; oral
3.4
8.1
38
118
P29
ICPC
Psychological sympt/compl other
3.2
8.1
42
141
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
7.5
8.0
18
25
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
7.9
75
358
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
7.9
79
385
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.9
7.9
21
37
J01DB01
ATC
cefalexin; oral
2.0
7.9
344
2874
L03
ICPC
Low back symptom/complaint
2.0
7.9
109
615
R40.2
ICD-10 Finland
Coma, unspecified
11.1
7.8
14
13
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.9
7.8
31
84
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.6
7.8
34
100
L12
ICPC
Hand/finger symptom/complaint
2.4
7.8
69
317
N05BA06
ATC
lorazepam; systemic, sublingual
3.7
7.8
33
95
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
6.1
7.8
20
34
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
7.7
78
383
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.0
7.7
44
157
H53.1
ICD-10 Finland
Subjective visual disturbances
3.5
7.7
35
107
N01
ICPC
Headache
2.4
7.7
68
312
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
7.6
39
130
M79.7
ICD-10 Finland
Fibromyalgia
4.8
7.6
24
52
F33
ICD-10 Finland
Recurrent depressive disorder
5.6
7.6
21
39
F10.20
ICD-10 Finland
Alcohol dependence currently independent
5.2
7.5
22
44
UKC02
NOMESCO Finland
Cystoscopy
2.3
7.5
72
345
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
7.5
85
443
N06AX03
ATC
mianserin; oral
4.0
7.4
28
73
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
4.8
7.3
23
50
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
7.2
70
339
N05AH02
ATC
clozapine; systemic
6.2
7.1
18
30
R11
ICD-10 Finland
Nausea and vomiting
2.8
7.1
45
172
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
7.1
41
148
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.6
7.1
52
217
N06AX17
ATC
milnacipran; oral
10.3
7.1
13
13
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
4.6
7.1
23
52
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
5.0
6.9
21
44
AA40B
NOMESCO Finland
NA
14.1
6.9
11
8
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.1
6.9
37
128
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.3
6.9
24
58
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
6.3
6.8
17
28
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
6.8
48
197
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.6
6.8
48
197
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.0
6.8
39
140
N06BA04
ATC
methylphenidate; oral
4.9
6.8
21
45
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
17.0
6.8
10
6
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
7.4
6.8
15
21
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.8
6.6
40
150
N05BA12
ATC
alprazolam; oral
2.6
6.6
49
206
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.5
6.6
54
237
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.2
6.6
19
38
R06AE07
ATC
cetirizine; oral
1.7
6.6
189
1354
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
5.9
6.5
17
30
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
6.5
99
576
M79.1
ICD-10 Finland
Myalgia
2.3
6.5
61
290
T81.9
ICD-10 Finland
Unspecified complication of procedure
7.6
6.5
14
19
R4130
NOMESCO Finland
Speech therapy
7.6
6.5
14
19
R4120
NOMESCO Finland
Occupational therapy
3.1
6.5
33
111
F99
ICD-10 Finland
Mental disorder, not otherwise specified
5.3
6.4
18
35
F10.25
ICD-10 Finland
Alcohol dependence continuous use
5.3
6.4
18
35
R5140
NOMESCO Finland
Monitoring the use of the aid
2.5
6.4
50
216
N06AX26
ATC
vortioxetine; oral
2.9
6.4
37
135
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
9.5
6.3
12
13
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.9
6.3
19
40
F13.29
ICD-10 Finland
Addiction caused by sedative and hypnotic UNS
18.3
6.3
9
5
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
7.2
6.3
14
20
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
7.2
6.3
14
20
F44.88
ICD-10 Finland
Other definite dissociation disorder
+∞
6.3
6
*
P77
ICPC
Suicide/suicide attempt
27.1
6.2
8
*
F45.0
ICD-10 Finland
Somatization disorder
27.1
6.2
8
*
SPAT1254
SPAT
Administration of medicine
2.1
6.2
72
376
A02BC03
ATC
lansoprazole; oral
1.8
6.2
111
681
K59.1
ICD-10 Finland
Functional diarrhoea
3.2
6.2
31
103
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
6.2
87
492
M54.1
ICD-10 Finland
Radiculopathy
4.2
6.2
22
55
N03AF02
ATC
oxcarbazepine; oral
4.0
6.2
23
60
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
4.8
6.2
19
41
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.5
6.2
27
81
C01CA24
ATC
epinephrine; parenteral
3.0
6.2
33
115
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
6.1
115
716
J01MA02
ATC
ciprofloxacin; systemic
1.7
6.1
150
1021
R60.0
ICD-10 Finland
Localized oedema
2.4
6.1
49
217
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
6.1
46
197
183
Kela drug reimbursment
Lamotrigin and topiramate
10.2
6.1
11
11

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
50
75
7.33
32.50
2.9
4.6
34.3
36.7
umol/l
0.19
38
66
52
103
5.54
25.57
3.4
1.8
—
—
—
0
0
277
1622
2.68
24.48
11.8
6.9
1.2
1.2
mmol/l
0.72
251
1378
197
997
2.66
23.13
4.3
2.1
369.7
270.0
u/l
0.29
184
948
253
1458
2.56
22.50
11.8
6.4
1.2
1.2
mmol/l
0.57
239
1332
42
78
5.81
22.06
1.4
1.8
4.0
3.6
mmol/l
1.25
37
72
187
968
2.53
20.44
6.5
3.7
7.4
7.4
ph
0.51
30
187
106
414
3.01
20.09
8.5
6.5
1.1
1.0
mmol/l
0.52
100
381
68
211
3.59
18.72
2.9
1.7
—
—
—
0
0
62
184
3.72
18.21
2.3
1.5
—
—
—
0
0
36
70
5.48
17.97
1.7
2.1
—
—
—
0
0
127
576
2.64
17.95
2.1
1.7
1158.4
1170.4
nmol/l
0.05
96
439
83
300
3.14
17.87
5.6
5.1
2.3
1.6
mmol/l
0.76
68
232
90
347
2.96
17.29
11.9
8.6
2.0
1.1
mmol/l
1.23
69
277
230
1389
2.26
16.93
6.8
4.9
35.2
36.1
g/l
1.71
216
1300
55
158
3.80
16.91
3.0
1.9
—
—
—
0
0
38
82
4.95
16.88
1.7
1.8
4.2
7.6
e6/l
0.39
33
62
68
230
3.28
16.29
3.0
1.7
—
—
—
0
0
219
1313
2.23
16.22
2.5
1.8
93.4
94.0
pmol/l
0.07
124
680
68
232
3.25
16.05
3.1
1.7
—
—
—
0
0
175
964
2.29
15.85
5.2
3.1
0.4
0.4
e6/l
0.04
136
719
67
230
3.22
15.65
3.0
1.7
—
—
—
0
0
73
268
3.03
15.20
8.9
7.9
8.7
8.5
mmol/l
0.07
66
257
270
1791
2.17
15.16
6.7
5.9
11.4
11.5
umol/l
0.05
260
1685
66
229
3.18
15.13
3.2
1.7
—
—
—
0
0
170
940
2.25
15.13
5.2
3.1
—
—
—
0
0
85
345
2.78
14.73
1.8
1.9
377.6
387.8
nmol/l
0.13
78
317
142
736
2.32
14.67
4.2
2.6
5.0
6.7
e6/l
0.69
124
650
164
904
2.24
14.62
2.6
1.9
2.8
2.9
mg/l
0.14
148
780
114
538
2.47
14.53
3.4
2.3
12.9
13.5
umol/l
0.36
108
500
70
261
2.97
14.15
5.0
4.7
5.0
4.6
kpa
0.86
65
252
161
899
2.19
13.76
6.9
4.3
—
—
—
0
0
150
822
2.20
13.38
2.1
1.9
1.0
1.0
mg/l
0.01
111
614
110
532
2.39
13.17
5.0
3.7
0.8
0.8
mmol/l
0.12
97
500
23
40
5.99
12.85
2.0
2.5
—
—
—
0
0
122
624
2.28
12.80
5.0
3.5
129.7
290.0
ng/l
0.75
89
448
92
416
2.50
12.73
2.6
1.7
—
—
—
0
0
155
876
2.14
12.68
8.4
6.9
—
—
—
0
0
322
2386
2.07
12.31
7.5
4.3
9.5
3613.7
e6/l
—
6
43
97
456
2.41
12.31
3.7
2.4
22.5
23.3
%
0.19
87
401
130
699
2.18
11.99
4.2
2.8
541.3
562.9
mosm/kgh2o
0.53
108
598
224
1473
1.98
11.91
2.9
2.3
73.4
74.4
nmol/l
0.22
211
1330
55
199
2.99
11.68
10.0
6.5
—
—
—
0
0
284
2036
1.97
11.63
9.9
4.9
6.7
6.5
mmol/l
0.54
270
1870
176
1074
2.01
11.50
5.4
3.3
24.2
138.0
e6/l
1.15
138
828
67
272
2.70
11.50
11.6
8.9
—
—
—
0
0
199
1274
1.96
11.28
6.1
3.8
23.8
80.0
e6/l
3.26
144
898
76
333
2.52
11.17
3.3
2.4
29.8
32.9
u/l
0.30
59
277
16
22
7.49
11.05
4.4
1.9
—
—
—
0
0
245
1702
1.90
10.70
7.3
6.1
8.4
8.4
%
0.05
235
1604
256
1804
1.90
10.70
7.4
5.8
0.6
0.6
e9/l
0.01
226
1572
185
1172
1.94
10.69
6.6
5.8
—
—
—
0
0
345
2690
2.02
10.56
9.7
6.9
77.7
78.4
u/l
0.11
332
2517
238
1644
1.89
10.52
7.2
5.8
0.7
0.7
%
0.02
227
1541
87
418
2.32
10.41
3.2
3.0
5.8
8.4
umol/l
0.98
74
352
256
1817
1.88
10.33
7.5
5.8
0.0
0.0
e9/l
0.32
226
1586
243
1697
1.88
10.31
7.1
5.7
3.0
2.7
%
0.84
233
1582
262
1876
1.88
10.26
7.6
5.8
2.0
2.0
e9/l
0.19
233
1675
250
1764
1.87
10.25
7.2
5.8
28.9
28.8
%
0.04
240
1663
179
1135
1.92
10.22
3.3
3.0
2.3
2.3
mmol/l
0.03
160
1010
247
1747
1.86
9.95
6.9
5.6
56.5
56.7
%
0.08
236
1649
261
1886
1.85
9.74
8.4
6.2
0.2
0.2
e9/l
0.66
232
1675
57
232
2.65
9.70
4.1
4.3
105.6
77.7
ng/l
0.82
50
211
45
162
2.96
9.62
5.7
5.3
23.8
23.8
mmol/l
0.04
38
150
195
1291
1.86
9.61
12.1
8.0
1.2
1.2
inr
0.13
64
405
166
1053
1.88
9.29
4.9
3.0
—
—
—
0
0
62
273
2.46
8.97
2.0
2.6
10.6
10.1
g/l
0.34
55
252
101
547
2.07
8.89
4.0
3.1
1.2
2.8
e6/l
2.44
50
301
168
1083
1.85
8.86
4.1
2.5
53.5
56.7
u/l
0.54
158
1001
352
2839
1.91
8.79
5.2
3.9
14.1
14.5
pmol/l
2.52
328
2593
30
90
3.49
8.63
2.6
2.7
—
—
—
0
0
245
1779
1.77
8.61
4.2
2.7
86.8
97.1
ug/l
0.64
231
1663
62
280
2.40
8.48
1.9
2.7
0.2
0.2
g/l
0.55
53
260
322
2539
1.82
8.48
6.1
4.1
—
—
—
0
0
16
30
5.48
8.26
1.6
2.2
—
—
—
0
0
277
2111
1.74
7.98
11.5
8.9
4.1
4.1
e9/l
0.08
249
1838
50
210
2.54
7.98
3.3
3.0
163.1
166.8
ng/l
0.03
45
186
106
608
1.96
7.88
1.3
1.3
18.7
28.1
iu/ml
0.53
20
194
15
28
5.50
7.77
15.5
10.0
0.6
0.6
mmol/l
0.08
15
28
41
159
2.73
7.66
17.0
12.8
—
—
—
0
0
25
72
3.61
7.64
3.0
2.4
125.3
130.7
g/l
0.45
19
52
126
773
1.86
7.61
1.8
1.5
21.4
20.9
nmol/l
0.13
119
661
332
2690
1.77
7.44
4.9
3.8
11.5
10.6
mm/h
0.61
318
2489
103
596
1.93
7.43
3.4
2.7
2.4
2.4
mmol/l
0.25
81
519
12
19
6.45
7.27
1.4
1.2
—
—
—
0
0
33
117
2.96
7.26
12.7
4.5
—
—
—
0
0
114
687
1.87
7.25
1.8
1.7
111111592.8
22581076.1
pmol/l
0.36
99
589
40
158
2.67
7.22
5.4
4.2
26.0
24.6
mmol/l
1.43
40
152
129
810
1.81
7.18
5.7
3.5
—
—
—
0
0
24
71
3.51
7.06
2.4
3.9
—
—
—
0
0
86
481
1.96
6.82
2.4
2.3
109.7
126.3
ug/g
0.25
65
379
53
247
2.29
6.74
4.2
3.6
—
—
—
0
0
44
189
2.46
6.71
1.7
2.2
—
—
—
0
0
14
29
4.94
6.49
1.6
3.0
—
—
—
0
0
28
97
3.00
6.43
1.5
1.4
252.7
298.3
ug/g
0.53
18
55
16
38
4.32
6.33
1.6
1.5
—
—
—
0
0
88
509
1.89
6.30
2.6
2.1
—
—
—
0
0
21
62
3.50
6.21
3.0
3.9
3.6
4.3
e9/l
0.79
21
62
86
498
1.89
6.12
1.5
1.4
572.6
513.3
titre
0.08
19
108
50
237
2.24
6.11
1.2
1.4
—
—
—
0
0
127
829
1.72
6.07
1.6
1.4
2.4
2.3
g/l
0.15
75
529
21
63
3.44
6.07
3.0
4.1
51.0
56.5
%
1.04
21
63
139
931
1.70
6.05
1.5
1.3
1.9
1.6
u/ml
0.11
40
262
175
1250
1.63
5.91
6.5
3.5
37.3
40.7
ng/l
0.12
112
775
98
604
1.78
5.69
1.3
1.3
4.6
9.0
u/ml
0.61
32
241
148
1024
1.65
5.63
3.9
3.3
7.5
7.8
mmol/l
0.38
131
871
123
816
1.68
5.48
5.6
3.7
1.0
1.0
kg/l
1.00
15
108
37
163
2.38
5.36
1.1
1.1
—
—
—
0
0
142
987
1.62
5.25
6.0
3.7
0.0
0.0
estimate
0.80
48
362
216
1659
1.55
5.19
13.5
8.9
0.0
0.0
e9/l
0.70
175
1367
75
438
1.84
5.18
1.2
1.2
—
—
—
0
0
24
87
2.85
5.12
1.2
1.3
—
—
—
0
0
70
404
1.86
5.01
27.5
19.7
1.4
1.2
inr
—
7
64
85
523
1.76
4.93
2.2
1.5
—
—
—
0
0
46
231
2.10
4.89
1.5
1.7
1.4
1.5
g/l
0.14
40
213
45
225
2.10
4.84
1.3
1.2
—
40.0
—
0
12
8
7
11.59
4.80
1.4
1.4
—
—
—
0
0
20
68
3.03
4.77
7.7
2.7
—
—
—
0
0
19
63
3.10
4.72
3.4
2.4
—
—
—
0
0
33
147
2.34
4.68
2.9
2.2
—
—
—
0
0
289
2402
1.51
4.59
4.5
3.5
—
—
—
0
0
47
246
2.01
4.49
8.0
4.8
7.4
7.4
ph
0.22
11
21
229
1820
1.50
4.49
5.7
3.5
0.0
0.0
estimate
0.00
52
366
10
22
4.62
4.32
1.3
2.9
—
—
—
0
0
17
56
3.11
4.28
2.3
3.7
—
—
—
0
0
23
91
2.60
4.19
1.9
1.2
—
—
—
0
0
55
314
1.85
4.08
1.9
1.4
—
—
—
0
0
17
58
3.00
4.05
1.4
1.4
12357.0
6596.5
e6/l
0.33
11
40
380
3391
1.59
4.03
6.5
4.5
1.8
2.2
mu/l
0.62
359
3143
27
119
2.34
3.95
1.3
1.2
—
—
—
0
0
225
1822
1.44
3.80
7.6
4.9
0.0
0.0
estimate
0.50
53
366
6
5
12.13
3.77
1.2
1.0
9.8
6.2
mg/g
—
6
5
6
5
12.13
3.77
1.2
1.0
—
—
—
0
0
16
55
2.98
3.77
3.3
3.6
70.0
61.0
%
0.80
16
55
20
78
2.63
3.76
2.1
3.1
46.8
58.9
mg/l
0.27
15
61
20
78
2.63
3.76
2.1
3.1
81.4
30.3
mg/l
0.47
15
61
367
3268
1.53
3.74
33.9
16.5
331.7
333.0
g/l
1.95
356
3244
18
67
2.75
3.70
4.8
2.4
16.0
16.1
%
0.03
12
31
53
309
1.80
3.69
1.5
1.3
66.3
162.7
iu/ml
1.85
18
123
149
1123
1.47
3.63
3.2
2.3
—
—
—
0
0
27
124
2.25
3.61
11.4
9.2
0.9
0.9
%
0.03
27
115
14
46
3.11
3.55
3.6
1.5
89.5
90.5
%
0.45
14
46
6
6
10.10
3.50
6.3
1.0
—
—
—
0
0
12
36
3.39
3.50
1.4
2.9
—
—
—
0
0
102
1398
0.66
3.49
2.6
2.6
—
—
—
0
0
132
981
1.48
3.43
2.8
2.0
—
—
—
0
0
225
1846
1.41
3.43
5.7
3.5
0.0
0.0
estimate
0.00
50
351
119
867
1.50
3.41
2.8
2.7
7249.7
5995.6
umol/l
0.11
103
759
9
18
5.07
3.38
1.2
1.4
139.1
133.7
nmol/l
—
9
18
53
318
1.75
3.36
1.3
1.2
—
—
—
0
0
16
59
2.77
3.35
5.2
2.3
—
—
—
0
0
39
214
1.90
3.29
1.5
1.4
16.4
21.7
iu/l
0.78
30
182
25
116
2.22
3.28
1.6
1.2
—
—
—
0
0
16
60
2.72
3.26
1.2
1.2
2.7
4.5
u/ml
—
8
28
211
1732
1.39
3.12
4.5
4.2
—
—
—
0
0
402
3698
1.55
3.06
31.4
14.3
139.5
139.6
mmol/l
0.21
389
3583
19
81
2.40
3.02
1.4
1.3
—
—
—
0
0
14
51
2.80
3.01
1.3
1.2
—
—
—
0
0
17
69
2.52
2.99
15.2
13.1
12.2
11.3
mmol/l
0.29
17
61
17
69
2.52
2.99
15.2
13.1
105.2
105.1
mmol/l
0.01
17
61
27
136
2.04
2.91
2.1
2.7
21.0
21.4
s
0.18
22
123
401
3707
1.51
2.77
31.5
14.4
3.9
4.0
mmol/l
0.58
390
3582
357
3230
1.42
2.76
30.3
15.7
13.8
13.6
%
1.20
351
3167
106
785
1.45
2.76
2.2
1.7
—
—
—
0
0
39
231
1.75
2.62
1.2
1.2
—
—
—
0
0
403
3743
1.49
2.58
28.2
12.8
19.9
22.3
mg/l
1.07
338
2910
10
33
3.07
2.54
1.4
1.5
—
—
—
0
0
9
26
3.51
2.49
1.2
1.1
—
—
—
0
0
42
259
1.68
2.45
2.2
2.9
72.0
71.3
e9/l
0.05
33
193
16
70
2.33
2.44
4.4
1.7
0.8
0.8
nmol/l
0.02
16
59
41
253
1.68
2.39
3.0
3.3
4.4
4.6
pmol/l
0.90
35
225
61
416
1.53
2.38
2.2
1.4
—
—
—
0
0
12
46
2.65
2.37
1.7
1.2
—
—
—
0
0
27
462
0.56
2.29
1.3
1.4
—
—
—
0
0
11
41
2.72
2.29
1.7
1.3
—
—
nmol/l
—
0
0
10
36
2.82
2.21
1.6
2.1
1.4
3.4
u/field
—
5
16
12
49
2.49
2.12
1.7
1.2
67.2
0.5
nmol/l
0.47
12
43
13
56
2.36
2.06
1.1
1.1
—
—
—
0
0
13
57
2.32
1.99
1.0
1.5
—
—
—
0
0
7
21
3.37
1.97
2.4
1.2
—
—
—
0
0
6
16
3.78
1.94
1.5
3.7
47.8
118.1
nmol/l
—
6
16
10
39
2.60
1.93
2.4
2.2
—
—
—
0
0
26
151
1.76
1.91
1.3
1.3
6.9
8.6
u/l
0.71
20
126
24
137
1.79
1.87
1.5
1.7
—
—
—
0
0
11
46
2.42
1.86
1.7
1.7
—
—
—
0
0
11
46
2.42
1.86
1.7
1.7
—
—
—
0
0
11
46
2.42
1.86
1.7
1.7
—
—
—
0
0
11
46
2.42
1.86
1.7
1.7
—
—
—
0
0
345
3181
1.30
1.84
6.5
5.2
39.6
39.3
mmol/mol
0.24
326
3001
54
381
1.47
1.82
1.2
1.3
—
—
—
0
0
415
3942
1.40
1.72
23.7
11.8
—
—
—
0
0
34
221
1.58
1.67
3.1
2.6
—
—
—
0
0
25
151
1.69
1.63
1.2
1.3
—
3.4
—
0
8
5
14
3.60
1.62
3.4
2.4
0.3
1.4
ug/l
—
5
14
13
63
2.09
1.61
1.2
1.1
—
—
—
0
0
6
20
3.02
1.58
2.3
2.3
24.2
26.3
umol/l
—
6
20
59
437
1.40
1.56
1.3
1.3
—
—
—
0
0
5
15
3.36
1.52
1.8
1.3
—
—
—
0
0
43
597
0.69
1.51
2.7
2.9
0.6
0.8
ug/l
1.40
28
359
17
95
1.82
1.45
1.8
1.5
—
—
—
0
0
6
22
2.75
1.44
2.3
2.7
—
—
—
0
0
410
3916
1.33
1.38
14.4
9.2
25.3
25.7
u/l
0.21
402
3780
6
23
2.63
1.37
1.0
1.0
—
—
—
0
0
106
875
1.27
1.35
5.9
4.6
—
—
—
0
0
23
144
1.63
1.34
1.3
1.3
—
—
—
0
0
17
98
1.76
1.32
1.3
1.4
197.7
236.8
u/ml
—
10
55
22
137
1.64
1.31
2.0
1.7
—
—
—
0
0
110
916
1.26
1.31
4.9
4.1
13.6
11.2
mg/mmol
0.24
75
603
34
236
1.47
1.29
2.7
2.3
3151.9
3790.6
u/l
0.09
11
106
27
179
1.54
1.26
1.1
1.1
—
—
—
0
0
33
230
1.47
1.23
1.4
1.2
—
—
—
0
0
6
26
2.32
1.19
1.0
2.5
—
646.1
—
0
11
8
38
2.12
1.19
1.5
1.2
—
—
—
0
0
26
176
1.50
1.13
1.5
1.4
—
—
—
0
0
12
66
1.84
1.10
2.3
2.0
—
—
—
0
0
14
228
0.60
1.07
2.5
1.6
—
—
—
0
0
7
33
2.14
1.06
1.1
1.3
—
0.1
u/ml
—
0
14
9
47
1.93
1.02
3.2
2.4
—
—
—
0
0
21
139
1.53
1.02
1.0
1.2
—
—
—
0
0
102
867
1.22
1.01
4.3
3.3
1199.2
372.1
mg/l
0.52
72
575
369
3520
1.21
0.99
28.8
13.6
39.4
40.1
%
0.95
278
2739
5
23
2.19
0.98
1.6
1.3
—
—
—
0
0
7
36
1.96
0.97
1.7
1.4
—
—
—
0
0
43
332
1.32
0.93
7.1
3.5
—
—
—
0
0
9
52
1.74
0.93
1.1
1.3
—
—
—
0
0
18
119
1.53
0.89
2.8
5.1
0.7
0.4
g/l
—
9
54
10
56
1.80
0.88
2.1
2.6
—
—
—
0
0
26
187
1.41
0.87
10.2
5.1
—
—
—
0
0
87
1014
0.83
0.86
4.1
4.6
1.7
2.6
ug/l
1.41
79
894
6
31
1.95
0.84
1.0
1.2
—
—
—
0
0
10
57
1.77
0.84
1.2
1.4
—
—
—
0
0
360
3454
1.17
0.77
5.0
4.0
5.9
5.8
mmol/l
0.91
338
3166
0
28
0.00
0.76
0.0
2.5
—
—
—
0
0
70
592
1.21
0.75
2.1
1.7
—
—
—
0
0
7
38
1.85
0.74
1.1
3.2
2.8
3.5
nmol/l
—
7
38
9
57
1.59
0.71
1.0
1.2
—
—
—
0
0
20
273
0.72
0.70
1.3
1.4
—
—
—
0
0
9
58
1.56
0.70
1.4
1.2
—
—
—
0
0
5
27
1.86
0.68
2.6
5.7
11.3
11.0
%
—
5
27
8
55
1.46
0.56
1.4
1.4
—
—
—
0
0
21
160
1.33
0.54
4.1
3.6
—
—
—
0
0
154
1428
1.12
0.51
2.4
2.0
—
—
—
0
0
10
143
0.69
0.48
1.4
1.5
—
—
—
0
0
16
121
1.33
0.44
5.9
6.9
1.4
1.4
mg/l
0.05
16
110
34
285
1.21
0.44
3.4
3.9
1.4
0.7
%
0.67
12
92
22
272
0.80
0.42
1.3
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
3.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
8
59
1.36
0.41
2.0
1.3
—
—
—
0
0
10
138
0.72
0.41
1.2
1.4
—
—
—
0
0
10
138
0.72
0.41
1.2
1.4
—
—
—
0
0
12
88
1.37
0.40
2.5
2.0
10.6
10.5
mg/l
0.02
12
80
9
69
1.31
0.37
2.0
1.8
—
—
—
0
0
42
368
1.15
0.35
1.7
1.4
—
—
—
0
0
345
3531
0.92
0.34
4.5
4.0
4.5
4.6
mmol/l
2.70
326
3303
34
294
1.17
0.33
3.5
3.9
—
—
—
0
0
21
174
1.22
0.32
1.8
1.4
305.0
262.4
miu/ml
—
9
87
14
112
1.26
0.28
2.0
2.6
—
—
—
0
0
30
261
1.16
0.28
3.7
4.1
0.1
0.1
%
—
8
79
12
94
1.28
0.28
1.2
1.2
0.7
1.5
u/ml
—
6
38
332
3388
0.93
0.26
4.1
3.6
1.4
1.3
mmol/l
1.89
310
3148
9
72
1.25
0.25
1.0
1.1
—
—
—
0
0
9
72
1.25
0.25
1.0
1.1
—
—
—
0
0
50
456
1.11
0.24
1.6
1.8
—
—
—
0
0
6
84
0.71
0.24
1.2
1.3
—
—
—
0
0
345
3511
0.94
0.23
4.3
4.0
1.4
1.4
mmol/l
3.45
324
3268
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
47
510
0.91
0.20
1.6
1.5
—
—
—
0
0
10
80
1.26
0.20
1.2
1.6
210.6
219.4
pmol/l
—
10
75
354
3585
0.95
0.16
4.9
4.4
2.6
2.8
mmol/l
2.90
334
3333
11
92
1.20
0.16
6.2
4.7
—
—
—
0
0
6
80
0.75
0.15
1.0
1.1
—
—
—
0
0
112
1078
1.05
0.15
4.7
3.2
—
—
—
0
0
422
4194
1.05
0.11
38.0
18.7
255.0
252.1
e9/l
0.41
415
4093
118
1150
1.03
0.10
1.4
1.6
—
—
—
0
0
94
913
1.04
0.09
5.6
3.5
—
—
—
0
0
422
4197
1.05
0.09
37.8
18.6
90.5
90.4
fl
0.18
415
4143
6
54
1.11
0.09
1.0
1.6
—
—
—
0
0
6
55
1.09
0.09
3.7
2.2
9.4
78.0
u/ml
—
6
50
29
308
0.94
0.08
2.8
3.8
3.1
46.9
ug/l
0.98
22
245
422
4198
1.04
0.08
37.8
18.6
30.1
30.2
pg
0.64
415
4143
422
4199
1.04
0.08
38.0
18.6
4.4
4.5
e12/l
3.30
414
4089
422
4202
1.04
0.06
38.0
18.7
6.8
6.8
e9/l
0.05
414
4087
422
4203
1.03
0.06
38.3
18.7
132.1
135.5
g/l
5.01
415
4143
13
120
1.09
0.05
3.5
3.1
17.5
1571.2
u/ml
0.72
13
101
11
113
0.97
0.00
32.5
8.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
38.7
—
0
6
0
6
0.00
0.00
0.0
1.0
—
16.9
—
0
6
5
50
1.00
0.00
1.4
1.1
9.8
12.3
u/l
—
5
45
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
2650.0
—
0
7

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: R18_SOMNOLENCE – Somnolence

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).