Interstitial emphysema and related conditions originating in the perinatal period

P16_INTERSTITIAL_EMPHY_RELATED_COND_ORIGINA_PERINA_PERIOD

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P25 Cause of death: ICD-10 — P25 2 out of 7 registries used, show all original rules.	54
4. Check minimum number of events None	54
5. Include endpoints None	54
6. Filter based on genotype QC (FinnGen only)	54

Control definitions (FinnGen only)

Control exclude: P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P2
Name in latin: Syndromata pulmonum rimosorum origine perinatalia

NAME	P16_INTERSTITIAL_EMPHY_RELATED_COND_ORIGINA_PERINA_PERIOD
CONTROL_EXCLUDE	P16_RESPI_CARDIOV_DISORD_SPECIFIC_PERINA_PERIOD
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P25
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P25
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Interstitial emphysema and related conditions originating in the perinatal period based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	4158	1500	2658
Only index persons	1854	652	1202
Unadjusted period prevalence (%)
Whole population	0.06	0.04	0.07
Only index persons	0.04	0.02	0.05
Median age at first event (years)
Whole population	-	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	54	24	30
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

102

2.93

3.43

3.2

3.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

145

2.70

3.14

3.6

3.8

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

10.74

3.02

1.8

1.2

—

(3044640) Blood type and Crossmatch panel - Blood

118

2.63

2.88

3.4

2.9

—

(3027653) Mycophenolate [Mass/volume] in Serum or Plasma

8.94

2.79

9.8

5.2

1.5

1.3

mg/l

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

5.15

2.68

2.0

1.2

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

2.78

2.43

34.9

15.1

1.4

1.0

mg/l

1.55

(3004119) Hemoglobin [Mass/volume] in Venous blood

3.62

2.42

15.3

23.6

118.4

123.4

g/l

—

(3042936) Bacteria identified in Isolate by Culture

3.09

2.42

2.2

1.9

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

6.69

2.41

2.0

1.4

—

(3019225) pH of Specimen

6.69

2.41

5.2

5.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

6.69

2.41

4.0

2.8

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.87

2.36

2.3

1.5

—

(40761535) Cells panel - Urine sediment

5.00

2.32

12.8

3.6

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

3.36

2.25

4.1

2.1

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

147

2.28

2.23

22.2

8.7

1.4

1.1

mmol/l

0.33

105

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

3.25

2.17

3.9

2.1

—

(4035726)

3.83

2.12

2.4

1.9

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

363

2.74

2.10

21.4

9.4

58.1

51.7

umol/l

0.67

363

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

3.64

2.02

1.9

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

161

2.16

2.00

13.0

4.2

—

(3045462) Protein/Creatinine [Ratio] in Urine

4.05

1.98

5.3

5.0

41.1

51.0

g/mol

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

4.85

1.97

1.8

3.9

26.2

17.1

umol/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.45

1.94

3.4

1.7

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

3.15

1.93

11.4

24.1

0.8

—

(3021901) Oxygen saturation in Capillary blood

4.44

1.85

14.4

7.2

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.21

1.82

6.0

3.6

0.3

0.5

e6/l

0.46

(3023368) Bacteria identified in Blood by Culture

2.29

1.78

2.5

3.7

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

3.17

1.77

3.0

1.5

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

2.45

1.74

3.3

7.9

88.6

90.1

0.08

(36304419) Bacteria [Presence] in Urine

142

2.06

1.73

8.5

3.9

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

3.04

1.70

3.0

1.4

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

3.39

1.70

14.8

18.8

106.7

123.8

g/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

102

2.13

1.68

5.3

3.8

0.7

1.5

e6/l

0.68

(3044889) 12 lead EKG panel

149

0.39

1.65

3.1

2.2

—

(44790047)

3.22

1.62

3.3

1.5

—

(44790048)

3.22

1.62

3.3

1.5

—

(44806118)

3.22

1.62

3.3

1.5

—

(44790049)

3.22

1.62

3.3

1.5

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

3.53

1.55

36.0

11.8

23.9

23.0

mmol/l

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.53

1.55

1.4

1.7

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

2.54

1.51

4.4

1.9

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

158

1.91

1.46

5.0

2.8

1.3

1.1

mmol/l

0.77

148

(3020393) Adenovirus Ag [Presence] in Stool

3.31

1.46

1.8

1.9

—

(3016502) Oxygen saturation in Arterial blood

2.60

1.43

14.9

24.2

98.5

93.4

—

(3022313) Gas panel - Capillary blood

133

1.93

1.43

21.3

8.3

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

1.41

0.0

1.1

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

3.11

1.38

3.0

1.2

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.55

1.27

17.2

27.2

0.8

0.7

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.55

1.27

17.2

27.4

97.7

96.9

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.55

1.27

17.2

27.2

0.5

1.0

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

165

1.80

1.24

5.5

3.1

2.8

2.5

mmol/l

1.05

152

(3011397) Hemoglobin [Presence] in Urine by Test strip

106

1.86

1.18

7.5

2.9

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.63

1.16

2.2

1.4

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

141

1.78

1.16

20.9

8.1

24.8

24.1

mmol/l

1.25

141

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.50

1.10

1.6

2.2

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

162

1.71

1.06

5.6

2.9

1.3

1.4

mmol/l

0.72

150

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.38

1.04

4.2

1.1

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

172

1.69

1.04

5.5

3.0

4.4

4.2

mmol/l

0.63

161

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.03

1.02

4.3

1.7

—

(3015736) pH of Urine

129

1.71

0.99

10.4

3.0

—

(3003694) ABO and Rh group [Type] in Blood

129

1.71

0.99

1.5

—

(3018095) Leukocytes [#/volume] in Urine

174

1.66

0.98

13.3

4.9

2.3

18.5

e6/l

3.91

117

(3035637) Corticotropin [Mass/volume] in Plasma

2.26

0.94

1.7

2.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.95

0.93

4.1

1.6

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.85

0.88

16.7

22.3

0.8

1.2

mmol/l

2.40

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.81

0.0

2.3

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.81

0.0

1.5

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.80

0.0

1.3

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.80

0.0

1.3

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

1.78

0.79

12.1

8.7

1096.6

1240.6

ng/l

—

(40768804) Tissue Pathology biopsy report

1.75

0.78

1.6

1.7

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.27

0.78

1.2

2.0

—

(3002256) Pathology report gross observation

2.17

0.76

1.2

1.3

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.17

0.76

19.4

26.5

—

(40768797) Stomach Pathology biopsy report

2.08

0.74

1.4

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.73

0.73

4.0

1.7

—

(3000850) Epithelial cells [#/volume] in Urine

1.62

0.71

12.7

2.7

3.1

7.2

e6/l

1.15

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

426

1.73

0.67

23.0

11.0

21.4

22.7

mg/l

0.10

292

(3026782) Osmolality of Urine

1.61

0.66

6.8

3.1

428.7

592.4

mosm/kgh2o

1.95

(40761872) Peanut recombinant (rAra h) 2 IgE Ab [Units/volume] in Serum

0.00

0.61

0.0

1.3

—

49.3

—

(3008898) HLA-B27 [Presence]

0.00

0.61

0.0

1.1

—

(3000991) Gas panel - Venous blood

127

1.48

0.57

25.8

11.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.47

0.54

1.7

—

(1761868) Lipid panel - Serum or Plasma

1.59

0.54

1.5

1.8

—

(3026008) Bacteria identified in Urine by Culture

1.49

0.50

4.8

2.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

235

1.38

0.49

10.9

3.6

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

168

1.39

0.49

29.9

13.9

24.4

24.9

mmol/l

0.37

168

(42870588) Differential panel, method unspecified - Blood

236

1.37

0.47

12.8

9.2

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

1.43

0.44

2.3

3.1

315.5

719.9

u/l

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.42

0.0

3.3

—

5.5

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.42

0.0

1.4

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.42

0.0

1.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.63

0.39

5.4

2.6

—

(3012544) pH of Venous blood

136

1.35

0.38

22.9

10.2

—

(40761511) CBC panel - Blood by Automated count

400

1.33

0.28

15.0

7.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.67

0.28

4.8

2.4

—

(3006598) pH of Arterial cord blood

0.69

0.28

1.0

—

(3041096) Erythrocytes [Presence] in Urine by Automated

0.71

0.26

15.5

2.8

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.33

0.25

24.0

5.3

—

(3009542) Hematocrit [Volume Fraction] of Blood

444

1.39

0.25

23.7

16.3

37.6

38.1

0.23

408

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

435

1.33

0.24

5.1

3.8

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

135

1.25

0.23

13.5

8.8

23.6

23.4

mmol/l

0.17

127

(40768443) Skin Pathology biopsy report

0.00

0.21

0.0

1.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.00

0.21

0.0

2.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.21

0.0

1.2

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.6

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.21

0.0

1.2

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.21

0.0

2.2

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.24

0.21

1.5

2.5

0.8

1.0

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.21

0.20

1.0

1.7

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.20

0.0

1.3

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.25

0.19

1.4

1.5

39.0

84.7

u/ml

—

(36660697) Celiac disease serology panel - Serum

0.80

0.16

1.0

1.2

—

(3006315) Basophils [#/volume] in Blood

288

1.16

0.15

16.5

8.6

0.0

e9/l

0.71

220

(3001604) Monocytes [#/volume] in Blood

290

1.14

0.13

16.5

8.6

0.7

0.6

e9/l

0.59

221

(3000494) Fungus identified in Specimen by Culture

1.17

0.10

1.4

2.3

—

(40758558) Short blood count panel - Blood

184

1.13

0.10

11.3

6.4

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.07

0.09

2.3

4.9

6.7

7.8

g/l

—

(3002030) Lymphocytes/100 leukocytes in Blood

302

0.90

0.09

16.7

8.3

40.9

38.5

0.38

294

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

152

0.88

0.08

1.6

2.1

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.10

0.08

1.8

2.2

—

(3021589) Normoblasts [#/volume] in Blood

298

0.93

0.04

13.1

9.1

0.0

e9/l

0.50

212

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

159

1.09

0.04

16.1

6.6

96.8

110.0

ml/min/173m2

—

(3022096) Basophils/100 leukocytes in Blood

279

1.07

0.03

15.1

8.6

0.5

0.6

0.73

271

(3013650) Neutrophils [#/volume] in Blood by Automated count

312

1.04

0.00

17.2

9.6

3.3

3.5

e9/l

0.25

245

(3018010) Neutrophils/100 leukocytes in Blood

292

0.97

0.00

15.1

8.2

43.9

45.6

0.23

284

(3006504) Eosinophils/100 leukocytes in Blood

284

1.03

0.00

16.3

8.5

3.0

3.3

0.30

274

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

215

1.03

0.00

1.5

2.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

111

0.98

0.00

16.1

3.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.7

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3016273) Islet cell 512 Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.0

1.7

—

(3007566) Smooth muscle Ab [Titer] in Serum

0.00

0.0

1.7

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.6

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

0.00

0.0

4.3

—

24.3

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.1

—

(40761871) Peanut recombinant (rAra h) 3 IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

0.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.0

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.0

1.8

—

30.6

—

(3002621) Streptococcal DNAse B [Units/volume] in Serum

0.00

0.0

1.0

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.4

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

0.0

7.9

—

8.8

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

98.5

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.4

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

0.0

1.4

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.0

—

(40761873) Peanut recombinant (rAra h) 1 IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.99

0.00

1.2

1.8

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.3

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.4

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.7

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.88

0.00

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.2

—

(3014373) Corynebacterium diphtheriae Ab [Units/volume] in Serum

0.00

0.0

2.2

—

(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

2.1

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

4.0

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.4

—

(3034368) Herpes virus 6 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3007164) IgA [Mass/volume] in Serum or Plasma

197

1.01

0.00

1.4

1.9

1.6

1.3

g/l

0.18

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_INTERSTITIAL_EMPHY_RELATED_COND_ORIGINA_PERINA_PERIOD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_INTERSTITIAL_EMPHY_RELATED_COND_ORIGINA_PERINA_PERIOD.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_INTERSTITIAL_EMPHY_RELATED_COND_ORIGINA_PERINA_PERIOD – Interstitial emphysema and related conditions originating in the perinatal period

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Interstitial emphysema and related conditions originating in the perinatal period

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints