Other encephalitis

G6_ENCEPHOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1004

4. Check minimum number of events

None

1004

5. Include endpoints

None

1004

6. Filter based on genotype QC (FinnGen only)

1004

Control definitions (FinnGen only)

Control exclude
G6_NEUINFL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8321 4179 4069
Only index persons 7092 3622 3470
Unadjusted period prevalence (%)
Whole population 0.12 0.12 0.11
Only index persons 0.13 0.13 0.13
Median age at first event (years)
Whole population 44.69 46.74 42.37
Only index persons 42.17 44.29 39.97

-FinnGen-

Key figures

All Female Male
Number of individuals 1004 555 449
Unadjusted period prevalence (%) 0.19 0.19 0.20
Median age at first event (years) 48.41 44.27 53.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
892
Matched controls
8918
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
6853.6
323.0
406
*
TAB00
NOMESCO Finland
Lumbar puncture
18.9
153.9
247
177
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
+∞
110.8
104
*
32309
ICD-8 Finland
Encephalitis, myelitis and encephalomyelitis, Unspecified
+∞
105.3
99
*
A86
ICD-10 Finland
Unspecified viral encephalitis
297.0
105.3
105
*
G04.8
ICD-10 Finland
Other encephalitis, myelitis and encephalomyelitis
+∞
90.1
85
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.7
87.5
225
376
AA1AD
NOMESCO Finland
CT of head and brain
4.2
70.2
337
1128
XA800
NOMESCO Finland
Neuropsychological investigation
10.0
64.4
135
156
G40.9
ICD-10 Finland
Epilepsy, unspecified
13.6
62.3
111
92
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.3
60.6
142
198
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.4
59.1
106
89
N03AX14
ATC
levetiracetam; systemic
14.9
54.6
93
69
5AB01
NOMESCO Finland
NA
504.1
48.8
48
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.0
45.6
212
651
G05.1
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
+∞
45.2
43
*
G05.8*M32.1
ICD-10 Finland
Encephalitis in systemic lupus erythematosus
+∞
44.1
42
*
G05.1*J09
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in influenza caused by certain identified influenza viruses
+∞
43.1
41
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
12.7
40.3
73
62
ZX120
NOMESCO Finland
Intravenous
4.6
39.5
148
366
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.5
37.2
144
367
N03AF02
ATC
oxcarbazepine; oral
8.1
36.7
85
114
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.7
35.8
108
209
G05.1*B01.1
ICD-10 Finland
Varicella encephalitis
+∞
34.6
33
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
19.5
33.0
50
27
A87.9
ICD-10 Finland
Viral meningitis, unspecified
26.2
32.6
45
18
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
32.0
191
697
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
10.2
31.8
64
67
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
30.8
412
2397
G05.1*B02.0
ICD-10 Finland
Zoster encephalitis
+∞
30.4
29
*
G03.9
ICD-10 Finland
Meningitis, unspecified
+∞
30.4
29
*
B00.4
ICD-10 Finland
Herpesviral encephalitis
+∞
30.4
29
*
R4120
NOMESCO Finland
Occupational therapy
4.6
29.8
109
260
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
29.8
235
1021
R50.9
ICD-10 Finland
Fever, unspecified
3.1
29.3
184
690
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
13.6
27.7
48
37
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
10.4
27.3
54
55
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
22.6
27.1
39
18
XF400
NOMESCO Finland
ECG with 12 standard connections
2.9
26.6
184
733
N03AG01
ATC
valproic acid; systemic, rectal
4.6
26.4
97
232
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.8
26.4
121
356
3238B
ICD-9 Finland
Encephalitis, myelitis and encephalomyelitis, Other causes of encephalitis[ENCEPHALITIS (MYELITIS,ENCEPHALOMYELITIS) VIROSA]
+∞
26.2
25
*
A28
ICPC
Limited function/disability NOS
3.0
25.7
162
606
R4110
NOMESCO Finland
Physiotherapy
2.4
25.5
271
1375
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
16.0
24.8
40
26
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.4
23.9
124
402
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
48.1
23.4
28
6
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
23.2
177
743
R4150
NOMESCO Finland
Neuropsychological rehabilitation
19.1
23.2
35
19
N03AX12
ATC
gabapentin; oral
2.7
22.9
175
734
WX892
NOMESCO Finland
Monitored bed care
3.8
22.0
97
275
R20.2
ICD-10 Finland
Paraesthesia of skin
4.1
21.5
88
233
R41.0
ICD-10 Finland
Disorientation, unspecified
7.1
21.4
53
79
G35
ICD-10 Finland
Multiple sclerosis
7.7
20.9
49
67
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
20.7
223
1121
N03AX16
ATC
pregabalin; oral
2.3
20.5
236
1223
2AB04
NOMESCO Finland
NA
49.2
20.2
24
5
N03AX18
ATC
lacosamide; systemic
17.8
20.1
31
18
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
58.9
20.0
23
*
G05.1*J10.8
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in influenza caused by other identified influenza virus
+∞
19.9
19
*
B94.1
ICD-10 Finland
Sequelae of viral encephalitis
+∞
19.9
19
*
R51.80
ICD-10 Finland
Headache
2.5
19.8
169
751
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
19.2
277
1580
183
Kela drug reimbursment
Lamotrigin and topiramate
14.4
19.2
32
23
6BA02
NOMESCO Finland
NA
35.2
19.0
24
7
N03AB02
ATC
phenytoin; systemic
13.2
18.5
32
25
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.1
18.4
106
369
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.7
18.2
138
572
TKC20
NOMESCO Finland
Catheterisation of bladder
3.6
18.1
86
259
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.9
17.8
75
204
N05BA09
ATC
clobazam; oral
16.0
17.6
28
18
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
12.9
17.2
30
24
G05.1*A85.0
ICD-10 Finland
Encephalitis, myelitis or encephalomyelitis (in) enteroviral
+∞
16.7
16
*
R33
ICD-10 Finland
Retention of urine
3.3
16.5
87
284
XA400
NOMESCO Finland
EEG
18.3
16.5
25
14
H02AB06
ATC
prednisolone; systemic
1.8
16.5
412
2846
N99
ICPC
Neurological disease other
9.7
16.0
32
34
J01MA12
ATC
levofloxacin; systemic
2.3
16.0
167
818
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
6.1
15.7
43
74
H02AB07
ATC
prednisone; oral
2.4
15.6
144
662
F05.9
ICD-10 Finland
Delirium, unspecified
6.9
15.4
38
57
WW400
NOMESCO Finland
Plasmaferesis
45.8
15.1
18
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
15.1
142
658
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
16.8
14.8
23
14
N71
ICPC
Meningitis/encephalitis
+∞
14.6
14
*
L28
ICPC
Limited function/disability (L)
2.3
14.6
146
697
L04AX01
ATC
azathioprine; systemic
3.8
14.3
60
164
C03CA01
ATC
furosemide; systemic
2.0
14.2
223
1291
M05BA04
ATC
alendronic acid; oral
2.9
14.2
90
333
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.5
14.2
67
202
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
13.9
90
338
L04AA06
ATC
mycophenolic acid; systemic
6.4
13.9
36
58
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
24.2
13.8
19
8
R4130
NOMESCO Finland
Speech therapy
6.3
13.8
36
59
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
76.3
13.6
15
*
32308
ICD-8 Finland
Encephalitis, myelitis and encephalomyelitis, Alia definita
+∞
13.6
13
*
G04.0
ICD-10 Finland
Acute disseminated encephalitis
+∞
13.6
13
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.1
13.4
75
253
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
13.4
82
298
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
12.4
13.1
23
19
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
5.9
13.1
36
63
G37.3
ICD-10 Finland
Acute transverse myelitis in demyelinating disease of central nervous system
50.8
12.9
15
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
50.8
12.9
15
*
J01DB01
ATC
cefalexin; oral
1.8
12.8
709
6050
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
5.5
12.8
37
69
R42
ICD-10 Finland
Dizziness and giddiness
2.0
12.8
189
1065
109
Kela drug reimbursment
Multiple sclerosis
7.2
12.7
30
43
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.2
12.4
38
76
J05AB11
ATC
valaciclovir; oral
2.3
12.2
124
595
R11
ICD-10 Finland
Nausea and vomiting
2.7
12.1
86
341
N05BA01
ATC
diazepam; systemic, rectal
2.2
11.9
125
610
H02AB09
ATC
hydrocortisone; systemic
4.3
11.9
43
103
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.0
11.8
70
249
N03AF01
ATC
carbamazepine; oral, rectal
3.3
11.8
60
192
N03AX09
ATC
lamotrigine; oral
3.3
11.6
58
184
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
11.6
160
876
JN4BD
NOMESCO Finland
Extensive body CT
2.4
11.5
98
431
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
11.5
149
795
G41.9
ICD-10 Finland
Status epilepticus, unspecified
13.8
11.5
19
14
G73.7*M32.1
ICD-10 Finland
Myopathy in systemic lupus erythematosus
+∞
11.5
11
*
G02.0*B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
11.5
11
*
5CM18
NOMESCO Finland
NA
35.5
11.3
14
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
25.4
11.2
15
6
N28
ICPC
Limited function/disability (N)
8.4
10.8
23
28
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.6
10.8
78
313
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.5
10.7
84
353
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
10.6
83
347
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
7.1
10.6
25
36
N05CF01
ATC
zopiclone; oral
1.7
10.6
257
1698
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
8.6
10.6
22
26
A02BC02
ATC
pantoprazole; systemic
1.6
10.5
521
4168
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
+∞
10.4
10
*
R53
ICD-10 Finland
Malaise and fatigue
1.9
10.4
174
1017
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.5
10.4
26
41
G40.89
ICD-10 Finland
Other epilepsy
16.3
10.4
16
10
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
32.9
10.3
13
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.9
10.3
63
228
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.7
10.2
25
38
J01AA02
ATC
doxycycline; systemic
1.6
10.2
639
5408
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.7
10.0
42
116
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
9.9
87
387
G61.0
ICD-10 Finland
Guillain-Barré syndrome
20.3
9.8
14
7
N05AH04
ATC
quetiapine; oral
1.9
9.8
152
866
WX730
NOMESCO Finland
Conventional respirator
6.2
9.7
25
41
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.4
9.7
28
53
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
6.5
9.6
24
38
N03AX11
ATC
topiramate; oral
4.3
9.6
34
81
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
+∞
9.4
9
*
WX704
NOMESCO Finland
Intubation
2.5
9.1
71
297
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
7.1
9.1
21
30
F05.8
ICD-10 Finland
Other delirium
15.8
9.0
14
9
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
8.9
34
87
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
8.9
114
604
J01MA02
ATC
ciprofloxacin; systemic
1.6
8.9
300
2152
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
6.4
8.8
22
35
RS221
NOMESCO Finland
NA
5.4
8.8
25
47
SPAT1254
SPAT
Administration of medicine
1.9
8.8
132
743
A41.9
ICD-10 Finland
Sepsis, unspecified
3.6
8.6
37
105
A02BC01
ATC
omeprazole; systemic
1.7
8.6
212
1396
A69.2
ICD-10 Finland
Lyme disease
3.1
8.5
46
156
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
8.0
8.4
18
23
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
8.4
85
408
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.3
8.3
24
46
G05.1*J11.8
ICD-10 Finland
Encephalitis, myelitis or encephalomyelitis in suspected influenza
+∞
8.3
8
*
N02AA05
ATC
oxycodone; systemic
2.0
8.3
112
605
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.9
8.3
33
88
N06AX11
ATC
mirtazapine; oral
1.6
8.3
258
1806
J96.0
ICD-10 Finland
Acute respiratory failure
6.6
8.2
20
31
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
8.1
60
246
G41.0
ICD-10 Finland
Grand mal status epilepticus
33.7
8.1
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.1
221
1496
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
8.0
108
583
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.8
8.0
32
86
SPAT1216
SPAT
Assessment of functional ability
1.9
8.0
120
673
N02BE01
ATC
paracetamol; systemic, rectal
1.6
8.0
707
6278
B01AC04
ATC
clopidogrel; oral
2.0
7.9
109
594
H53.2
ICD-10 Finland
Diplopia
3.5
7.9
35
103
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
7.9
422
3345
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
5.5
7.9
22
41
A06AD11
ATC
lactulose; oral
1.9
7.8
111
610
B02.8
ICD-10 Finland
Zoster with other complications
15.2
7.7
12
8
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
7.5
7.7
17
23
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
7.5
7.7
17
23
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.7
7.6
50
192
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.5
213
1447
M03BX01
ATC
baclofen; systemic
4.0
7.5
28
71
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
7.5
64
283
P01BA02
ATC
hydroxychloroquine; oral
2.2
7.5
77
373
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
7.4
172
1111
J01FF01
ATC
clindamycin; systemic
1.6
7.3
218
1503
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.4
7.3
34
104
R47.0
ICD-10 Finland
Dysphasia and aphasia
6.9
7.3
17
25
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.0
7.3
40
138
F07.1
ICD-10 Finland
Postencephalitic syndrome
+∞
7.3
7
*
B02.0
ICD-10 Finland
Zoster encephalitis
+∞
7.3
7
*
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
+∞
7.3
7
*
J05AB01
ATC
aciclovir; systemic
1.7
7.3
166
1065
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
7.3
57
242
R1260
NOMESCO Finland
Evaluation of communicative skills
4.9
7.2
22
46
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
30.3
7.2
9
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
7.1
83
423
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
20.2
7.1
10
5
Z71.8
ICD-10 Finland
Other specified counselling
1.6
7.1
194
1307
A29
ICPC
General symptom/complaint other
2.0
7.1
87
453
N02AX02
ATC
tramadol; systemic, rectal
1.5
7.1
321
2438
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.1
7.1
76
375
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
7.1
98
534
L04AX07
ATC
dimethyl fumarate; oral
10.1
7.0
13
13
N06AA09
ATC
amitriptyline; systemic
2.1
7.0
80
404
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
7.1
7.0
16
23
N03AE01
ATC
clonazepam; systemic
2.4
7.0
56
241
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
7.0
37
125
G81.9
ICD-10 Finland
Hemiplegia, unspecified
5.9
6.9
18
31
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
6.9
95
515
SPAT1255
SPAT
Intravenous administration of medicine
2.3
6.9
60
268
N30.0
ICD-10 Finland
Acute cystitis
1.9
6.9
106
602
A04
ICPC
Weakness/tiredness general
1.9
6.9
106
602
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
6.9
89
474
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.4
6.9
57
249
N05BA04
ATC
oxazepam; oral
1.6
6.8
195
1325
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.8
6.8
41
150
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
5.4
6.8
19
36
G40
ICD-10 Finland
Epilepsy
6.2
6.8
17
28
M32
ICD-10 Finland
Systemic lupus erythematosus
40.4
6.8
8
*
WX872
NOMESCO Finland
Intensive care
2.7
6.8
44
169
N03AX23
ATC
brivaracetam; systemic
16.8
6.8
10
6
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.8
6.7
26
69
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
22.7
6.7
9
*
G95.9
ICD-10 Finland
Disease of spinal cord, unspecified
22.7
6.7
9
*
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
22.7
6.7
9
*
N03AX22
ATC
perampanel; oral
22.7
6.7
9
*
N06AX16
ATC
venlafaxine; oral
1.8
6.6
109
630
N05CD08
ATC
midazolam; nasal, systemic
3.9
6.6
25
65
C07AB07
ATC
bisoprolol; oral
1.5
6.5
325
2506
WX110
NOMESCO Finland
Local anesthesy
1.4
6.5
567
4880
C01CA24
ATC
epinephrine; parenteral
2.3
6.4
58
266
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
6.4
67
327
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
6.4
137
862
R55
ICD-10 Finland
Syncope and collapse
2.0
6.4
82
436
B01AB05
ATC
enoxaparin; parenteral
1.5
6.4
221
1573
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.2
6.3
59
273
N29
ICPC
Neurological sympt/complt other
4.2
6.3
22
53
B02.1
ICD-10 Finland
Zoster meningitis
+∞
6.3
6
*
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
+∞
6.3
6
*
3238X
ICD-9 Finland
Encephalitis, myelitis and encephalomyelitis, Other causes of encephalitis[ENCEPHALITIS (MYELITIS, ENCEPHALOMYELITIS) ALIA DEF]
+∞
6.3
6
*
R51
ICD-10 Finland
Headache
2.4
6.3
48
203
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.8
6.2
19
40
M31.1
ICD-10 Finland
Thrombotic microangiopathy
26.9
6.2
8
*
UKC02
NOMESCO Finland
Cystoscopy
1.8
6.2
116
700
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.1
6.2
18
36
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
5.8
6.2
16
28
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.3
6.1
28
86
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.2
6.1
58
273
N06AX21
ATC
duloxetine; oral
1.9
6.1
87
482
G44.8
ICD-10 Finland
Other specified headache syndromes
6.1
6.0
15
25
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.6
6.0
40
157

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
293
155
26.28
307.65
1.7
1.5
—
—
—
0
0
331
188
25.77
307.65
1.7
1.3
677.0
449.6
mg/l
8.09
324
177
285
172
22.74
307.65
1.8
1.5
661.6
814.3
e6/l
0.08
225
139
285
172
22.74
307.65
1.7
1.4
51.7
8.5
e6/l
4.23
218
134
213
66
40.69
307.65
1.4
1.9
—
—
—
0
0
326
167
28.43
307.65
1.6
1.2
3.6
3.8
mmol/l
1.28
311
158
201
72
34.65
306.25
1.6
1.6
—
—
—
0
0
181
85
25.76
248.95
1.8
1.7
—
—
—
0
0
138
63
25.24
190.83
1.4
1.1
58.2
40.5
mg/l
1.54
122
49
132
59
25.61
183.92
1.3
1.1
341.2
232.7
mg/l
3.12
122
53
120
55
24.64
165.25
1.4
1.2
—
—
—
0
0
283
547
6.81
148.25
2.7
2.3
22.6
20.0
au/ml
—
6
30
263
490
6.92
142.51
1.5
1.3
44.8
31.8
au/ml
—
5
27
68
17
42.83
112.75
1.2
1.0
—
—
—
0
0
263
619
5.40
109.06
3.4
2.5
9.8
10.6
g/l
1.91
243
568
63
36
18.60
78.03
1.3
1.3
—
—
—
0
0
79
72
11.82
75.38
3.2
2.1
1.3
1.1
e9/l
1.20
48
40
88
97
9.85
73.52
1.2
1.1
—
—
—
0
0
65
49
14.11
69.60
3.2
2.2
0.2
0.2
e9/l
1.17
59
41
66
52
13.52
68.87
3.2
2.1
523.0
494.3
e6/l
0.12
59
42
449
2045
3.16
68.27
5.6
4.2
—
—
—
0
0
62
54
12.17
60.75
2.9
1.9
14.1
11.3
%
0.63
38
25
63
57
11.73
60.23
2.7
2.1
709.6
670.2
e6/l
0.12
25
23
299
1167
3.22
57.73
2.8
2.3
28.9
29.7
s
2.28
293
1132
459
2292
2.85
56.55
3.0
2.1
217.1
270.8
u/l
0.36
446
2162
63
66
10.12
54.42
2.9
2.0
49.0
39.7
%
—
10
7
497
2645
2.74
53.26
9.8
6.0
—
—
—
0
0
574
3359
2.66
49.66
9.1
6.4
1.2
1.2
mmol/l
2.36
529
3058
46
34
14.13
49.62
1.5
1.0
1596.3
1558.3
miu/ml
0.05
46
34
553
3203
2.62
48.48
6.2
4.9
34.8
35.9
g/l
3.56
524
2981
39
22
18.40
48.31
2.7
2.0
184.2
271.1
e6/l
—
24
9
112
248
4.96
48.08
4.8
1.5
0.2
0.2
g/l
3.26
104
240
113
259
4.79
46.51
4.9
1.5
1.1
1.2
g/l
2.37
105
249
606
3730
2.58
45.81
9.9
7.0
1.2
1.2
mmol/l
0.65
516
3163
634
3994
2.59
45.50
9.9
5.9
0.6
0.6
e9/l
1.68
563
3474
597
3663
2.55
45.21
10.1
6.1
0.6
0.7
%
0.43
572
3431
634
4012
2.57
44.77
9.9
6.0
0.0
0.0
e9/l
0.03
562
3493
688
4544
2.63
44.08
7.6
5.0
6.6
6.7
mmol/l
0.07
660
4218
604
3771
2.51
43.36
10.2
6.1
2.5
2.8
%
3.18
580
3527
605
3793
2.50
42.83
10.5
6.3
8.8
8.5
%
1.01
582
3572
641
4129
2.53
42.73
9.9
6.0
1.8
2.0
e9/l
2.28
574
3656
640
4158
2.49
41.26
10.8
6.3
0.2
0.2
e9/l
1.53
572
3672
90
188
5.16
41.23
3.2
3.6
27.9
35.3
umol/l
3.10
78
161
612
3908
2.45
40.83
10.3
6.1
26.4
28.3
%
4.20
588
3666
376
1944
2.49
40.07
5.3
4.0
90.2
91.6
%
0.52
368
1894
604
3858
2.42
39.91
9.9
5.9
58.5
57.0
%
2.37
583
3636
393
2082
2.46
39.61
4.4
3.0
—
—
—
0
0
152
496
3.43
38.14
2.4
1.7
1.1
1.4
g/l
1.10
136
460
395
2126
2.41
38.13
4.5
3.1
0.3
0.4
e6/l
1.68
313
1596
676
4644
2.39
36.28
13.8
9.1
4.2
4.1
e9/l
0.95
603
4072
400
2207
2.35
36.04
5.2
3.9
7.4
7.4
ph
1.29
64
425
416
2342
2.33
35.68
4.5
3.2
29.0
86.1
e6/l
1.23
332
1798
493
2994
2.27
35.11
8.6
9.0
1.2
1.2
inr
0.31
128
916
464
2768
2.26
34.28
5.4
3.7
36.7
97.7
e6/l
2.57
351
1934
229
999
2.67
34.07
7.9
5.9
1.0
1.1
mmol/l
0.39
211
925
156
559
3.12
33.37
2.4
2.8
66.0
66.7
g/l
0.43
140
514
262
1269
2.44
30.98
3.9
2.8
0.9
1.0
e6/l
0.63
151
711
328
1755
2.29
30.83
1.7
1.9
—
—
—
0
0
737
5470
2.31
29.83
7.0
4.1
—
—
—
0
0
293
1525
2.30
29.16
3.8
2.8
547.9
560.1
mosm/kgh2o
0.42
250
1310
707
5185
2.23
29.06
6.6
4.2
388.0
1486.9
e6/l
—
7
80
132
464
3.12
29.01
2.1
2.5
—
—
—
0
0
250
1219
2.40
28.89
4.7
3.8
0.8
0.8
mmol/l
0.54
224
1149
300
1611
2.23
27.44
3.2
2.6
4.7
6.5
e6/l
1.79
271
1423
45
72
6.50
27.17
1.3
1.3
6.7
7.7
g/l
0.53
34
50
244
1206
2.35
27.16
4.1
2.9
3.1
2.6
e6/l
0.21
133
650
348
1998
2.14
26.76
9.9
6.8
—
—
—
0
0
86
246
3.73
26.10
2.0
2.6
10.7
10.5
g/l
0.13
66
213
44
72
6.35
25.99
1.3
1.3
3.0
2.8
g/l
0.17
33
49
44
72
6.35
25.99
1.3
1.3
0.3
0.4
g/l
0.71
33
49
173
747
2.59
25.73
2.5
2.1
354.0
369.8
nmol/l
0.54
163
693
577
4035
2.01
25.31
7.3
6.3
10.5
12.0
umol/l
2.98
550
3815
44
74
6.17
25.30
1.3
1.3
—
—
—
0
0
769
6027
2.18
23.93
10.6
7.4
77.1
78.8
u/l
0.56
736
5672
30
35
8.80
23.74
1.4
1.4
—
—
—
0
0
29
7
42.55
23.71
1.4
4.4
—
—
—
0
0
260
1388
2.18
23.65
3.7
3.7
100.8
398.5
ng/l
3.23
196
1032
77
219
3.72
23.54
1.9
2.2
11.5
11.1
mg/l
0.17
68
203
451
2961
1.95
23.05
2.3
1.9
91.0
94.7
pmol/l
0.88
253
1557
74
208
3.76
23.01
1.8
2.8
36.9
38.0
g/l
0.57
58
183
152
650
2.58
22.92
7.9
8.1
8.3
9.1
mmol/l
0.78
144
620
58
140
4.34
22.18
1.5
1.3
3.3
5.9
u/ml
0.73
36
57
54
124
4.55
21.99
1.4
1.8
0.4
0.9
g/l
2.40
43
94
246
1328
2.13
21.51
1.8
1.7
998.1
1173.4
nmol/l
2.62
192
1002
148
650
2.50
21.02
10.2
9.1
—
—
—
0
0
27
9
30.78
20.63
1.1
1.0
—
—
—
0
0
92
319
3.07
20.54
2.9
2.5
22.4
21.3
s
0.43
85
291
33
52
6.53
20.19
3.5
2.6
43.2
42.3
%
0.05
15
14
104
390
2.86
20.19
5.2
4.7
23.3
24.0
mmol/l
1.27
95
355
362
2284
1.91
20.18
4.1
2.9
—
—
—
0
0
155
721
2.36
19.32
4.7
4.1
1.6
1.8
mmol/l
0.37
129
572
505
3577
1.83
19.24
13.5
9.2
0.0
0.0
e9/l
0.53
412
2931
151
696
2.38
19.21
9.0
7.7
1.4
1.4
mmol/l
0.19
139
661
51
126
4.21
18.92
4.1
5.9
324.5
380.6
umol/l
2.18
44
108
23
6
39.20
18.61
1.0
1.0
—
—
—
0
0
23
27
8.69
18.07
2.7
1.7
—
—
—
0
0
208
1120
2.08
17.98
1.8
1.3
389.1
477.2
titre
0.67
66
241
167
830
2.21
17.72
10.6
8.9
1.4
1.0
mmol/l
0.49
130
651
167
837
2.19
17.33
10.6
8.8
5.1
5.1
kpa
0.06
154
803
194
1031
2.09
17.32
1.7
1.6
—
—
—
0
0
167
838
2.19
17.28
10.6
8.8
12.0
12.4
kpa
0.34
154
807
724
5842
1.86
16.85
6.1
4.0
13.4
11.3
mm/h
3.13
687
5417
26
39
6.82
16.64
1.2
1.3
123.9
159.0
nmol/l
2.34
26
39
73
250
3.07
16.62
1.2
1.1
—
—
—
0
0
38
83
4.72
16.45
1.2
1.1
—
—
—
0
0
133
621
2.32
16.33
3.9
3.6
4.9
4.6
kpa
0.87
127
603
84
318
2.79
15.98
2.5
2.1
1.7
1.4
g/l
1.32
70
278
376
2547
1.76
15.75
3.8
3.3
2.3
2.4
mmol/l
1.79
330
2252
283
1766
1.84
15.60
4.6
3.4
—
—
—
0
0
448
3210
1.71
15.20
2.7
2.3
75.2
75.7
nmol/l
0.13
409
2903
286
1819
1.80
14.67
2.1
1.9
1.0
1.2
mg/l
0.36
226
1364
44
118
3.85
14.63
1.3
1.4
65.5
64.7
mmol/l
0.04
36
102
174
944
2.02
14.51
2.2
1.6
—
—
—
0
0
56
178
3.27
14.44
1.2
1.4
—
—
—
0
0
304
1977
1.77
14.42
2.4
2.2
3.1
3.0
mg/l
0.36
257
1679
158
833
2.06
14.23
2.9
2.8
1.8
1.8
%
0.00
137
759
266
1683
1.79
13.76
2.1
1.4
2.1
2.4
g/l
1.73
194
1039
132
674
2.10
12.90
1.6
1.4
—
—
—
0
0
142
747
2.05
12.81
11.5
9.4
95.6
95.8
%
0.10
137
720
906
8104
2.21
12.80
25.9
13.4
22.8
23.1
mg/l
0.13
793
6358
23
40
5.86
12.77
1.0
1.0
408.3
238.4
ng/l
0.98
18
22
36
94
3.94
12.44
2.8
2.3
—
—
—
0
0
136
712
2.05
12.42
2.3
2.4
39.7
36.4
u/l
0.11
122
598
72
288
2.62
12.31
2.5
2.2
0.7
2.4
ug/l
0.94
65
255
43
129
3.44
12.16
1.1
1.1
—
—
—
0
0
398
2890
1.62
12.02
4.6
3.5
43.2
41.3
ng/l
0.06
281
1904
17
23
7.50
11.87
1.5
1.4
—
—
—
0
0
35
93
3.86
11.81
1.2
1.3
—
—
—
0
0
22
40
5.60
11.68
1.0
1.0
618.8
586.6
ng/l
0.12
16
23
50
169
3.06
11.67
1.3
1.4
90.6
100.8
u/ml
—
8
34
36
99
3.73
11.58
1.7
1.6
—
—
—
0
0
36
99
3.73
11.58
1.7
1.6
—
—
—
0
0
36
99
3.73
11.58
1.7
1.6
—
—
—
0
0
36
99
3.73
11.58
1.7
1.6
—
—
—
0
0
167
962
1.88
11.52
1.4
1.7
—
—
—
0
0
509
3962
1.58
11.23
5.4
3.5
0.0
0.0
estimate
0.80
96
737
902
8134
2.07
11.19
27.8
15.1
139.1
139.6
mmol/l
7.17
891
7918
503
3910
1.57
11.12
7.6
4.8
0.0
0.0
estimate
0.50
98
765
503
3911
1.57
11.10
5.4
3.4
0.0
0.0
estimate
0.00
94
750
183
1098
1.82
11.06
2.5
2.1
—
—
—
0
0
44
143
3.17
10.98
1.1
1.1
—
—
—
0
0
103
510
2.14
10.87
1.5
1.3
125.6
227.1
u/ml
1.16
96
465
133
728
1.95
10.67
2.9
2.5
0.2
0.2
g/l
1.18
119
688
339
2423
1.60
10.62
3.0
2.5
57.6
57.0
u/l
0.10
320
2265
116
607
2.03
10.56
2.9
3.0
67.6
71.7
e9/l
0.57
84
472
35
101
3.55
10.51
2.4
2.6
—
—
—
0
0
901
8159
2.02
10.47
27.9
15.2
3.9
4.0
mmol/l
0.83
886
7932
256
1720
1.66
10.24
1.7
1.5
18.5
20.3
nmol/l
1.69
238
1471
221
1430
1.70
10.20
1.7
1.6
—
—
—
0
0
342
2469
1.58
10.19
2.8
2.4
—
—
—
0
0
14
18
7.87
10.16
1.5
1.3
—
—
—
0
0
44
150
3.02
10.14
3.0
4.0
—
—
—
0
0
51
190
2.77
10.03
1.2
1.4
304.0
239.3
u/ml
0.50
32
116
83
391
2.22
9.91
12.2
11.0
24.4
24.4
mmol/l
0.00
73
371
12
13
9.33
9.88
1.4
1.1
16.4
18.6
umol/l
0.63
12
13
31
86
3.69
9.87
1.4
1.5
280.2
282.9
mosm/kgh2o
0.17
22
61
823
7296
1.71
9.62
5.5
4.6
1.8
2.0
mu/l
0.85
771
6725
54
213
2.62
9.52
1.9
1.2
17.5
2.7
u/ml
—
10
23
100
524
2.01
9.06
4.6
4.4
7.4
7.4
ph
—
10
64
26
68
3.90
9.00
1.7
1.2
—
—
—
0
0
88
441
2.09
9.00
10.5
8.5
25.2
24.3
mmol/l
1.48
82
413
52
208
2.58
8.93
3.3
3.8
92.9
32.9
mg/l
0.57
46
166
52
208
2.58
8.93
3.3
3.8
34.3
79.7
mg/l
0.83
45
166
104
557
1.97
8.86
4.0
4.1
80.3
80.5
ng/l
0.01
87
499
100
530
1.98
8.78
4.6
4.4
5.3
5.1
kpa
1.18
93
497
91
469
2.03
8.63
8.0
6.2
—
—
—
0
0
704
6076
1.53
8.50
4.6
3.9
14.8
14.7
pmol/l
0.78
660
5553
78
388
2.10
8.14
14.3
12.7
—
—
—
0
0
50
206
2.50
8.10
3.4
3.7
1.5
2.0
ratio
—
5
20
172
1107
1.67
7.95
3.0
2.4
2.3
2.3
g/l
0.10
161
1023
198
1322
1.62
7.92
3.5
2.9
2.4
2.4
mmol/l
0.36
168
1170
115
666
1.82
7.71
5.2
4.5
0.9
0.9
%
0.02
51
206
44
175
2.58
7.67
1.2
1.2
—
—
—
0
0
110
630
1.84
7.64
1.4
1.4
—
—
—
0
0
161
1029
1.67
7.63
3.1
2.4
18.4
23.3
%
5.76
132
887
76
385
2.05
7.57
4.7
4.6
—
—
—
0
0
107
610
1.84
7.55
4.8
4.4
0.6
0.5
%
0.13
42
153
457
3676
1.45
7.48
4.6
4.0
—
—
—
0
0
37
138
2.75
7.32
1.3
1.4
—
—
—
0
0
60
282
2.20
7.25
4.3
3.7
0.2
0.3
g/l
1.49
34
126
38
145
2.68
7.20
1.3
1.6
—
—
—
0
0
41
163
2.58
7.17
5.8
4.1
2.8
2.3
mmol/l
0.61
29
108
179
1193
1.61
7.17
3.0
2.4
11.5
13.3
umol/l
2.73
166
1099
24
70
3.49
7.15
1.4
1.1
—
—
—
0
0
41
164
2.56
7.08
5.1
4.6
—
—
—
0
0
260
1896
1.50
6.94
2.7
2.3
—
—
—
0
0
150
964
1.65
6.94
1.5
1.4
—
—
—
0
0
64
316
2.10
6.84
1.3
1.3
—
—
—
0
0
107
630
1.78
6.79
5.4
4.6
0.2
0.1
%
0.43
49
188
224
3035
0.66
6.72
2.7
2.7
—
—
—
0
0
275
2042
1.48
6.68
3.1
3.2
1101.7
1323.6
ng/l
0.77
226
1721
45
197
2.34
6.44
5.7
3.9
7.4
7.4
ph
0.07
40
161
97
564
1.80
6.42
2.4
3.0
190.6
207.4
ng/l
0.11
88
507
34
131
2.65
6.35
1.4
1.1
43397.7
77.6
iu/ml
—
6
30
27
93
2.96
6.19
3.3
4.0
—
—
—
0
0
439
3591
1.40
6.15
3.3
2.7
136.5
115.3
ug/l
0.70
401
3334
100
595
1.76
6.13
5.1
4.7
0.0
0.1
%
1.03
43
162
264
1975
1.46
6.10
3.4
2.7
1734.0
5778.9
umol/l
1.65
232
1715
15
35
4.34
6.04
1.5
1.9
—
—
—
0
0
10
16
6.30
5.96
3.6
2.1
16.2
14.8
umol/l
—
10
16
137
894
1.62
5.94
3.3
3.1
7.9
8.7
umol/l
0.23
114
767
103
624
1.73
5.93
4.3
3.2
—
—
—
0
0
25
85
2.99
5.87
1.8
1.5
—
—
—
0
0
47
224
2.15
5.54
4.0
3.3
—
—
—
0
0
11
21
5.29
5.53
2.0
1.4
—
—
—
0
0
134
897
1.57
5.22
28.7
20.9
1.2
1.3
inr
0.16
14
127
20
64
3.17
5.21
1.2
1.1
0.1
1.3
nmol/l
—
5
12
909
8562
1.65
5.17
16.4
9.9
27.9
26.8
u/l
1.05
884
8291
902
8495
1.61
4.94
21.3
12.4
—
—
—
0
0
30
125
2.44
4.84
1.2
1.2
—
—
—
0
0
16
48
3.37
4.62
1.1
1.0
—
—
—
0
0
607
5367
1.33
4.60
3.9
3.6
—
—
—
0
0
85
533
1.65
4.34
1.3
1.5
—
—
—
0
0
15
45
3.37
4.33
1.1
1.0
—
—
—
0
0
12
31
3.91
4.26
3.1
3.2
28.6
35.6
umol/l
—
7
24
10
23
4.38
4.09
1.0
1.2
—
—
—
0
0
94
616
1.58
4.03
2.4
2.5
4.6
7.9
ug/l
2.40
77
547
208
1602
1.38
3.91
1.6
1.7
36842534.1
31343710.0
pmol/l
0.05
190
1340
34
165
2.10
3.90
5.7
3.3
—
—
—
0
0
83
535
1.60
3.82
2.8
2.6
4.2
4.1
e9/l
0.10
63
432
22
89
2.50
3.81
1.3
1.2
—
—
—
0
0
11
29
3.82
3.81
1.4
1.5
—
—
—
0
0
6
5
12.06
3.76
1.2
1.0
—
—
—
0
0
258
2067
1.33
3.75
3.9
3.3
1042.9
331.9
mg/l
0.82
179
1345
744
6863
1.32
3.69
30.7
16.2
13.8
13.6
%
2.70
735
6727
50
285
1.79
3.63
6.7
4.8
—
—
—
0
0
36
184
1.99
3.62
4.2
2.4
—
—
—
0
0
89
592
1.55
3.60
1.3
1.2
199.6
156.1
iu/ml
0.35
32
240
89
596
1.54
3.50
6.3
3.7
1.2
1.2
mmol/l
1.64
79
525
284
2331
1.30
3.44
4.3
3.2
7.7
7.9
mmol/l
0.30
239
1977
177
1360
1.37
3.36
1.4
1.3
18.9
29.6
iu/ml
1.45
49
424
10
27
3.73
3.36
1.1
1.1
—
—
—
0
0
8
14
5.75
3.34
1.6
1.9
—
—
—
0
0
103
719
1.48
3.34
6.2
4.3
—
—
—
0
0
23
102
2.28
3.31
3.4
2.8
—
—
—
0
0
364
3101
1.27
3.27
2.0
2.0
—
—
—
0
0
267
2189
1.30
3.24
4.9
4.0
12.4
9.7
mg/mmol
0.43
183
1410
10
28
3.60
3.20
1.0
1.0
—
—
—
0
0
58
359
1.65
3.17
2.0
2.3
1960.8
3670.7
u/l
0.62
17
157
808
7598
1.32
3.11
27.5
14.2
39.3
40.2
%
2.32
598
5726
60
921
0.63
3.07
1.3
1.3
—
—
—
0
0
31
160
1.97
3.07
4.4
3.6
4.0
4.2
e9/l
0.24
31
160
18
74
2.46
3.06
3.7
3.3
—
—
—
0
0
93
650
1.47
3.01
1.2
1.2
—
—
—
0
0
13
47
2.79
2.82
1.1
1.1
1.0
1.1
ratio
—
7
19
31
166
1.90
2.79
5.0
3.9
57.5
56.5
%
0.17
31
166
31
166
1.90
2.79
3.0
2.2
16.9
16.5
%
0.17
14
85
73
496
1.51
2.73
3.3
3.5
4.3
4.6
pmol/l
1.49
62
439
16
66
2.45
2.72
1.1
1.1
—
—
—
0
0
71
481
1.51
2.69
4.6
2.7
—
—
—
0
0
7
15
4.69
2.60
1.0
1.4
—
—
—
0
0
17
74
2.32
2.59
1.5
1.4
11.2
12.3
mmol/l
—
10
16
19
88
2.18
2.52
1.2
1.4
301.9
363.9
pmol/l
0.29
12
69
8
21
3.83
2.46
1.1
1.1
—
—
—
0
0
14
57
2.48
2.45
3.9
3.4
—
—
—
0
0
24
124
1.96
2.42
2.7
1.5
—
—
—
0
0
748
7045
1.24
2.34
31.3
16.8
333.0
333.0
g/l
0.02
741
6999
47
302
1.58
2.29
1.3
1.3
211.6
246.8
miu/ml
0.22
19
144
9
29
3.12
2.23
2.8
3.0
—
—
—
0
0
10
36
2.80
2.20
1.9
5.6
72.4
66.4
mg/l
—
10
26
47
305
1.57
2.20
1.1
1.2
—
—
—
0
0
247
2096
1.24
2.18
6.0
3.7
0.0
0.0
estimate
1.08
93
747
209
1743
1.25
2.15
6.1
3.6
1.0
1.0
kg/l
0.25
37
236
17
81
2.12
2.13
1.4
1.4
—
—
—
0
0
85
626
1.39
2.13
2.1
2.2
13.1
13.1
nmol/l
0.00
76
567
26
145
1.81
2.12
3.0
2.6
—
—
—
0
0
756
7155
1.23
2.12
6.4
5.4
40.0
39.5
mmol/mol
0.62
705
6677
225
1900
1.24
2.07
1.3
1.3
2.9
1.5
u/ml
0.28
43
512
13
56
2.34
2.05
1.2
1.4
—
—
—
0
0
36
560
0.63
2.02
1.3
1.4
—
—
—
0
0
8
26
3.09
2.01
6.3
3.6
—
—
—
0
0
64
456
1.43
1.95
1.4
1.2
—
—
—
0
0
9
33
2.74
1.93
2.6
2.6
—
—
—
0
0
220
1867
1.23
1.93
7.1
4.6
—
—
—
0
0
9
34
2.66
1.86
1.0
1.1
—
—
—
0
0
8
28
2.87
1.86
2.5
2.9
—
—
—
0
0
6
17
3.54
1.84
1.2
1.5
—
—
—
0
0
47
320
1.49
1.82
2.2
1.8
—
—
—
0
0
12
53
2.28
1.81
1.8
1.3
—
—
—
0
0
11
47
2.36
1.78
1.4
1.3
—
—
—
0
0
16
81
1.99
1.75
1.8
1.9
17.4
21.1
nmol/l
1.40
16
76
28
170
1.67
1.75
2.2
2.0
127.9
130.1
g/l
0.15
17
129
39
258
1.53
1.73
1.3
1.2
—
—
—
0
0
5
13
3.86
1.71
1.2
1.0
—
—
—
0
0
932
9094
1.35
1.66
35.6
19.5
7.0
6.7
e9/l
3.13
912
8854
31
197
1.59
1.64
1.7
1.3
—
—
—
0
0
931
9085
1.34
1.64
35.6
19.5
256.3
251.6
e9/l
1.21
915
8866
19
105
1.83
1.63
2.0
1.8
—
—
—
0
0
931
9088
1.34
1.61
35.5
19.4
91.0
90.6
fl
1.76
919
8967
931
9089
1.33
1.60
35.4
19.4
30.3
30.2
pg
1.06
918
8967
931
9090
1.33
1.59
35.6
19.5
4.4
4.5
e12/l
9.89
909
8853
13
64
2.04
1.54
1.0
1.2
0.2
0.4
u/ml
—
5
26
931
9095
1.33
1.53
35.8
19.6
132.7
136.1
g/l
9.65
918
8968
5
15
3.34
1.52
2.4
1.3
—
—
—
0
0
5
16
3.14
1.44
1.4
1.6
—
—
—
0
0
5
16
3.14
1.44
3.0
1.1
—
—
—
0
0
9
39
2.32
1.43
1.2
1.1
416.2
496.2
u/l
—
9
34
9
40
2.26
1.40
2.8
2.3
—
—
—
0
0
13
67
1.95
1.38
1.2
1.1
—
—
—
0
0
22
136
1.63
1.33
1.1
1.2
—
—
—
0
0
8
35
2.30
1.27
1.0
1.3
—
—
—
0
0
9
45
2.01
1.23
1.3
1.2
—
—
—
0
0
8
38
2.11
1.18
1.4
1.2
—
—
—
0
0
0
33
0.00
1.16
0.0
3.0
—
—
—
0
0
0
33
0.00
1.16
0.0
6.1
—
—
—
0
0
5
20
2.51
1.15
2.8
2.8
—
—
—
0
0
16
95
1.70
1.14
1.0
1.2
—
—
—
0
0
44
328
1.36
1.12
3.7
1.9
—
—
—
0
0
11
58
1.91
1.12
1.9
2.3
—
1.7
—
0
6
49
372
1.33
1.11
2.9
2.4
—
—
—
0
0
31
218
1.44
1.10
1.7
1.4
268.1
317.2
ug/g
0.44
17
123
24
160
1.51
1.10
2.3
2.1
—
—
—
0
0
124
1055
1.20
1.10
2.5
2.5
212.6
126.8
ug/g
0.69
101
846
30
211
1.43
1.07
1.9
1.9
8.7
5.8
iu/l
0.59
11
72
10
52
1.93
1.06
1.4
1.5
—
1787.8
—
0
8
48
369
1.32
1.02
6.1
3.7
—
—
—
0
0
36
265
1.37
1.01
1.6
1.4
10.9
9.3
u/l
0.28
30
214
17
108
1.58
0.97
1.8
1.4
—
—
—
0
0
24
167
1.45
0.92
1.8
1.7
10029.5
13580.4
e6/l
0.25
19
125
19
126
1.52
0.91
1.7
1.3
—
—
—
0
0
120
1045
1.17
0.84
1.2
1.2
—
—
—
0
0
759
7790
0.89
0.79
4.4
4.1
1.4
1.5
mmol/l
1.98
698
7206
6
33
1.82
0.79
1.0
1.9
—
—
—
0
0
15
98
1.54
0.78
2.1
2.7
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
26
191
1.37
0.77
2.1
1.3
—
—
—
0
0
251
2313
1.11
0.76
3.8
4.6
2.5
2.5
ug/l
0.05
233
2070
81
690
1.19
0.75
6.3
3.7
—
—
—
0
0
12
75
1.61
0.75
1.2
1.1
—
—
—
0
0
19
133
1.44
0.74
1.2
1.2
134.9
37.6
u/l
0.37
14
117
240
2220
1.11
0.68
5.4
3.2
—
—
—
0
0
10
61
1.65
0.68
2.2
5.6
10.6
11.2
%
—
10
61
5
27
1.86
0.68
1.8
1.7
—
—
—
0
0
18
127
1.42
0.68
1.6
1.7
—
—
—
0
0
26
196
1.34
0.68
2.2
2.5
100.1
110.5
ug/min
0.08
17
119
23
170
1.36
0.68
1.2
1.1
—
—
—
0
0
23
170
1.36
0.68
1.2
1.1
—
—
—
0
0
144
1295
1.13
0.67
1.3
1.3
5.3
10.6
u/ml
1.06
48
521
7
44
1.59
0.65
1.0
1.3
8.5
6.2
ug/l
—
7
35
17
120
1.42
0.65
4.7
3.1
0.8
0.9
nmol/l
0.52
11
94
11
71
1.56
0.62
1.6
2.4
—
—
—
0
0
11
71
1.56
0.62
1.2
1.4
—
—
—
0
0
8
52
1.54
0.59
1.3
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
47
392
1.21
0.58
3.6
1.8
—
—
—
0
0
6
36
1.67
0.56
1.8
1.1
132.9
219.6
iu/ml
—
6
36
230
2145
1.09
0.56
4.4
3.7
—
—
—
0
0
35
285
1.24
0.54
8.6
2.6
—
—
—
0
0
6
38
1.58
0.54
1.2
1.3
—
—
—
0
0
9
62
1.46
0.53
1.4
1.5
1.0
1.0
g/l
—
9
62
9
65
1.39
0.50
1.0
1.1
—
—
—
0
0
81
718
1.14
0.50
3.3
4.3
4.1
29.8
ug/l
1.48
60
587
6
41
1.47
0.50
1.5
2.1
—
—
—
0
0
6
41
1.47
0.50
5.8
6.3
—
—
—
0
0
45
381
1.19
0.49
1.3
1.4
35.3
24.4
iu/l
1.01
35
311
10
68
1.48
0.47
1.9
1.6
—
—
—
0
0
770
7832
0.93
0.44
4.4
4.2
4.6
4.7
mmol/l
2.25
709
7286
49
423
1.17
0.44
3.5
1.8
—
—
—
0
0
5
31
1.62
0.43
1.4
12.6
—
—
—
0
0
5
31
1.62
0.43
3.0
2.4
—
—
—
0
0
17
217
0.78
0.41
1.4
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
15
114
1.32
0.41
1.7
1.5
—
—
—
0
0
773
7603
1.07
0.41
4.7
4.2
6.0
5.9
mmol/l
0.72
712
6964
17
216
0.78
0.40
1.3
1.4
—
—
—
0
0
93
846
1.11
0.40
1.3
1.3
—
—
—
0
0
144
1339
1.09
0.40
2.8
2.9
0.8
0.8
ug/l
0.01
98
831
49
428
1.15
0.39
3.5
1.8
—
—
—
0
0
14
106
1.33
0.39
3.1
2.7
—
—
—
0
0
10
137
0.73
0.39
9.1
2.8
—
—
—
0
0
0
19
0.00
0.39
0.0
1.7
—
94.2
—
0
12
244
2319
1.07
0.39
1.5
1.5
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
49
430
1.15
0.38
3.5
1.8
—
—
—
0
0
9
71
1.27
0.36
1.6
1.6
—
—
—
0
0
14
108
1.30
0.35
3.1
2.7
4.2
4.1
mmol/l
0.46
14
108
14
108
1.30
0.35
3.1
2.7
103.3
105.3
mmol/l
0.38
14
108
42
479
0.87
0.35
1.2
1.7
—
—
—
0
0
741
7524
0.94
0.35
4.0
3.7
1.4
1.3
mmol/l
2.19
680
6935
6
45
1.34
0.33
1.5
3.4
—
—
—
0
0
786
7960
0.94
0.32
4.9
4.5
2.7
2.8
mmol/l
2.94
718
7358
33
288
1.15
0.29
2.8
2.6
—
—
—
0
0
16
195
0.82
0.29
1.1
1.1
—
—
—
0
0
40
356
1.13
0.27
1.1
1.1
—
—
—
0
0
47
423
1.12
0.27
2.0
1.7
—
—
—
0
0
30
342
0.87
0.27
1.0
1.1
—
—
—
0
0
8
66
1.21
0.26
1.6
1.2
—
—
—
0
0
91
973
0.93
0.25
1.4
1.4
—
—
—
0
0
11
137
0.80
0.24
1.2
1.2
—
—
—
0
0
86
806
1.07
0.23
1.9
1.4
—
—
—
0
0
10
124
0.80
0.21
2.3
3.1
3.9
37.2
u/ml
—
10
117
0
11
0.00
0.21
0.0
1.0
—
0.6
—
0
6
0
10
0.00
0.21
0.0
1.0
—
173.2
—
0
10
12
145
0.83
0.21
1.1
1.1
3.1
4.2
u/ml
—
7
35
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
3.5
—
0
6
6
49
1.23
0.20
1.2
1.2
—
—
—
0
0
6
52
1.15
0.19
1.2
1.1
—
—
—
0
0
10
81
1.24
0.18
3.0
2.1
—
—
—
0
0
6
53
1.13
0.18
1.5
1.8
—
—
—
0
0
23
204
1.13
0.18
9.7
4.8
—
—
—
0
0
9
78
1.16
0.15
1.0
1.1
—
—
—
0
0
15
131
1.15
0.14
1.9
2.9
7.6
7.1
umol/l
—
8
98
90
938
0.96
0.13
1.9
1.8
—
—
—
0
0
20
221
0.90
0.13
1.3
1.5
—
—
—
0
0
27
293
0.92
0.12
1.7
1.7
—
—
—
0
0
15
167
0.90
0.10
1.2
1.2
—
—
—
0
0
23
249
0.92
0.10
10.7
9.8
—
—
—
0
0
11
96
1.15
0.10
2.7
2.4
33.1
33.2
pg
0.02
11
96
6
54
1.11
0.09
1.5
1.3
—
—
—
0
0
6
71
0.84
0.07
1.7
1.2
—
—
—
0
0
52
502
1.04
0.06
1.2
1.2
—
—
—
0
0
10
90
1.11
0.05
1.0
1.2
—
—
nmol/l
—
0
0
15
161
0.93
0.05
1.6
1.6
—
—
—
0
0
14
150
0.93
0.04
1.1
1.1
12.7
5.2
u/ml
—
8
88
199
2008
0.99
0.03
1.8
1.6
1.5
1.4
mmol/l
0.52
173
1712
98
992
0.99
0.02
1.1
1.2
—
—
—
0
0
16
168
0.95
0.02
1.1
1.1
0.6
2.9
u/ml
—
9
75
12
113
1.06
0.02
1.1
1.1
2.5
4.5
u/ml
—
7
43
14
144
0.97
0.00
1.1
1.1
1.5
1.4
u/ml
—
7
68
13
132
0.98
0.00
1.2
1.2
—
—
—
0
0
5
57
0.88
0.00
1.2
1.1
—
7.4
—
0
14
0
5
0.00
0.00
0.0
1.8
—
4.6
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
14.3
—
0
6
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
4.0
—
14.3
—
0
9
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
34.3
—
0
5

Mortality – FinRegistry

Association

Association between endpoint G6_ENCEPHOTH and mortality.

Females

Parameter HR [95% CI] p-value
G6_ENCEPHOTH 2.45 [2.02, 2.98] < 0.001
Birth year 0.991 [0.98, 1.0] 0.037

During the follow-up period (1.1.1998 — 31.12.2019), 661 out of 2876 females with G6_ENCEPHOTH died.

Males

Parameter HR [95% CI] p-value
G6_ENCEPHOTH 2.573 [2.12, 3.12] < 0.001
Birth year 0.987 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 676 out of 2598 males with G6_ENCEPHOTH died.

Mortality risk

Mortality risk for people of age

years, who have G6_ENCEPHOTH.

N-year risk Females Males
1 0.27% 0.56%
5 1.504% 3.404%
10 3.471% 7.97%
15 6.499% 14.497%
20 10.676% 23.104%

Relationships between endpoints

Index endpoint: G6_ENCEPHOTH – Other encephalitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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