No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
574 |
4. Check minimum number of eventsNone |
574 |
5. Include endpointsNone |
574 |
6. Filter based on genotype QC (FinnGen only) |
574 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Asymmetry of jaw
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5892 | 3581 | 2294 |
| Only index persons | 5631 | 3444 | 2187 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.06 |
| Only index persons | 0.11 | 0.13 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 19.42 | 20.42 | 17.77 |
| Only index persons | 20.03 | 21.27 | 18.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 574 | 431 | 143 |
| Unadjusted period prevalence (%) | 0.13 | 0.15 | 0.06 |
| Median age at first event (years) | 31.77 | 31.05 | 33.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 519
- Matched controls
- 5190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.10
ICD-10 Finland
Asymmetry of jaw
+∞
323.0
518
*
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
178.2
192.1
192
17
K07.13
ICD-10 Finland
Retrognaty, mandibular
66.1
176.0
201
49
SBB10
NOMESCO Finland
Teeth copy
19.4
167.3
288
313
EEC05
NOMESCO Finland
Le Fort I osteotomy
356.4
137.5
133
5
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
18.4
135.0
227
210
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
21.2
121.0
188
135
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
21.1
120.0
187
135
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
25.8
118.6
171
97
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
21.1
105.7
163
110
EB1MA
NOMESCO Finland
Cephalometry with X-ray
18.9
102.4
165
125
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
19.8
100.8
159
113
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
17.7
100.4
166
134
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
384.3
96.4
94
*
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
21.5
95.2
145
92
K07.24
ICD-10 Finland
Open bite
46.2
92.4
113
31
K07.14
ICD-10 Finland
Retrognaty, maxillary
146.8
82.8
86
7
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
15.8
80.0
137
115
K07.60
ICD-10 Finland
Snapping jaw
13.1
79.1
149
155
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
21.6
77.7
117
69
SAA04
NOMESCO Finland
Special inverstigation of mouth
10.3
73.2
158
212
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
11.9
68.5
134
147
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
7.0
67.2
195
411
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
102.6
65.8
71
8
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
91.3
64.9
71
9
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
19.7
64.7
100
62
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
123.5
61.4
65
6
SJC00
NOMESCO Finland
Bracket with fixed attachment
94.4
60.6
66
8
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
166.0
57.2
59
*
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
12.1
56.0
107
109
SJB60
NOMESCO Finland
External device grinding and adaptation
12.3
53.4
101
100
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
14.9
53.4
92
74
SAA03
NOMESCO Finland
Extended examination of mouth
4.2
51.2
360
1812
SJA01
NOMESCO Finland
Estimation of need for orthodontic care
98.2
48.8
53
6
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
7.3
44.9
117
199
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
12.2
44.7
84
81
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
464.8
43.9
43
*
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
5.9
40.2
125
266
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
12.7
39.9
73
66
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
86.6
36.4
40
5
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
32.1
35.8
47
16
EDC30
NOMESCO Finland
Genioplasty
193.0
35.2
36
*
SXC05
NOMESCO Finland
Other oral or dental procedure
5.6
35.2
112
242
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.2
34.6
265
1261
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
8.6
34.4
78
105
K07.23
ICD-10 Finland
Deep bite
8.7
33.9
76
100
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
8.5
33.8
77
104
SJB10
NOMESCO Finland
Fitting of loose orthodontic device with user information, demanding
13.2
33.1
59
50
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
7.8
32.1
77
113
EBB10
NOMESCO Finland
Insertion of dental implant
22.3
31.0
45
22
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
6.1
28.4
82
155
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
6.8
28.2
74
123
SJD50
NOMESCO Finland
Production and attachment of palatinal or lingual arrow
18.9
27.5
42
24
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
28.3
27.5
37
14
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
21.6
27.4
40
20
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
7.5
27.3
67
101
EB1WA
NOMESCO Finland
NA
102.2
26.9
29
*
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
6.0
26.4
77
147
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
42.5
26.1
32
8
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
26.7
25.6
35
14
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.6
24.2
290
1694
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
71.0
24.0
27
*
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
16.2
21.8
35
23
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
9.2
21.3
45
53
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
18.2
20.3
31
18
EBA10
NOMESCO Finland
Surgical removal of tooth
3.0
20.2
134
536
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
21.9
20.2
29
14
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
9.0
19.8
42
50
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
22.7
19.7
28
13
SJA02
NOMESCO Finland
Plan for orthodontic care
57.3
19.1
22
*
SXC03
NOMESCO Finland
Other oral or dental procedure
18.9
18.0
27
15
EBB15
NOMESCO Finland
Insertion of dental implant abutment
38.2
17.7
22
6
ZXA10
NOMESCO Finland
Bilateral
3.0
17.7
117
462
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
6.7
17.6
45
72
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
65.6
16.8
19
*
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
175.4
16.6
17
*
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
41.5
16.4
20
5
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
9.0
16.2
34
40
EEC02
NOMESCO Finland
Rapid expansion of maxilla
164.8
15.6
16
*
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
15.7
15.0
24
16
EG1CG
NOMESCO Finland
Extensive MRI examination of mandipular joint with high intensity magnet
19.1
14.8
22
12
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.0
14.8
61
167
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
9.8
14.1
28
30
K01.0
ICD-10 Finland
Embedded teeth
5.6
14.1
41
78
P01BA02
ATC
hydroxychloroquine; oral
3.5
13.6
65
202
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
13.4
153
805
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.0
13.3
55
151
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.1
13.1
77
276
K00.00
ICD-10 Finland
Hypodontia
7.3
13.1
31
45
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
20.7
12.5
18
9
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
133.1
12.5
13
*
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
133.1
12.5
13
*
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
7.4
12.5
29
41
J01CE02
ATC
phenoxymethylpenicillin; oral
2.1
12.4
402
3205
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
38.5
12.3
15
*
SJE90
NOMESCO Finland
Finishing face of orthodontick therapy
21.9
12.1
17
8
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
5.4
12.1
36
71
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.1
11.6
67
240
K07.4
ICD-10 Finland
Malocclusion, unspecified
7.2
11.5
27
39
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
122.6
11.5
12
*
K07.0
ICD-10 Finland
Major anomalies of jaw size
122.6
11.5
12
*
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
20.6
11.2
16
8
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
11.1
176
1053
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
18.3
10.8
16
9
EGC30
NOMESCO Finland
Prosthetic replacement of mandibular joint
112.2
10.5
11
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.3
10.3
51
164
K07.61
ICD-10 Finland
Cracking jaw joint
5.4
10.0
29
56
5241A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Anomalies of relationship of jaw to cranial base
56.1
9.7
11
*
SPB10
NOMESCO Finland
Production of temporary crone to tooth
11.7
9.6
17
15
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
101.8
9.4
10
*
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
+∞
9.4
9
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.1
9.3
52
181
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
8.0
9.2
20
26
SAA02
NOMESCO Finland
Basic examination of mouth
1.9
8.9
392
3236
R06.5
ICD-10 Finland
Mouth breathing
2.7
8.7
58
227
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
4.8
8.4
27
59
A07EC01
ATC
sulfasalazine; oral, rectal
2.9
8.3
49
179
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
8.1
90
458
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.9
8.1
32
86
G47.3
ICD-10 Finland
Sleep apnoea
2.1
8.0
95
495
TEG00
NOMESCO Finland
Punction of mandibular joint
22.4
8.0
11
5
M01AE02
ATC
naproxen; oral, rectal
1.7
8.0
310
2415
OIKK
NOMESCO Finland
NA
3.0
7.8
44
154
ZZH22
NOMESCO Finland
Graft of patients own bone, block
15.3
7.7
12
8
Q67.0
ICD-10 Finland
Facial asymmetry
45.7
7.7
9
*
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
18.7
7.6
11
6
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
7.6
141
874
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
81.2
7.4
8
*
4347
FHL
Osteotomy of the upper jaw
81.2
7.4
8
*
SPB20
NOMESCO Finland
Temporary bridge between two or more teeth
11.1
7.3
13
12
4343
FHL
Lower jaw open osteotomy
+∞
7.3
7
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
4.5
7.2
24
55
R4110
NOMESCO Finland
Physiotherapy
1.9
7.1
123
742
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.1
7.0
80
411
G50.1
ICD-10 Finland
Atypical facial pain
6.5
7.0
17
27
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
14.0
6.9
11
8
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
11.1
6.8
12
11
ECA50
NOMESCO Finland
Parodontal operation
11.1
6.8
12
11
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
22.8
6.7
9
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.1
6.7
24
60
K07.6
ICD-10 Finland
Temporomandibular joint disorders
8.0
6.6
14
18
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.2
6.6
33
109
M79.1
ICD-10 Finland
Myalgia
2.1
6.6
71
357
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
70.7
6.4
7
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.3
6.4
22
53
EBA40
NOMESCO Finland
Excision of apex of root of tooth
8.3
6.4
13
16
RT160
NOMESCO Finland
NA
18.3
6.3
9
5
EFB50
NOMESCO Finland
Orthodontic procedure connected with ortognathic surgery
+∞
6.3
6
*
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
27.0
6.2
8
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
399
3344
1.63
6.67
5.3
3.7
8.38
9.32
mm/h
1.22
386
3129
328
2698
1.50
5.36
8.8
8.2
3.66
3.97
e9/l
2.25
299
2374
291
2342
1.49
5.25
7.2
5.7
31.10
30.03
%
1.13
279
2207
289
2331
1.48
5.11
3.5
3.0
0.00
0.01
estimate
0.80
76
468
285
2298
1.48
5.01
3.5
3.0
0.00
0.00
estimate
0.00
73
471
285
2307
1.47
4.86
4.7
4.2
0.00
0.00
estimate
0.50
79
486
285
2308
1.47
4.85
7.0
5.5
54.66
55.87
%
1.18
273
2173
232
1809
1.47
4.77
3.6
3.0
—
—
—
0
0
165
1232
1.48
4.12
3.9
3.2
0.00
0.01
estimate
1.34
76
481
40
204
2.03
4.08
1.5
1.7
—
—
—
0
0
375
3271
1.42
3.87
6.9
6.7
71.51
76.91
u/l
2.70
364
3090
116
825
1.51
3.64
2.9
2.3
5.12
8.52
e6/l
1.89
104
726
91
621
1.55
3.44
3.2
3.3
176.16
390.81
ng/l
0.54
50
367
512
4792
1.63
3.33
12.5
10.5
18.18
19.92
mg/l
0.66
397
3621
20
430
0.45
3.29
2.8
4.8
—
—
—
0
0
23
103
2.28
3.26
4.8
3.7
55.13
56.56
%
0.27
23
103
172
1347
1.40
3.21
1.4
1.4
1.37
2.04
u/ml
0.49
48
370
224
1839
1.36
3.10
2.3
2.3
76.76
72.99
nmol/l
1.25
207
1696
218
1789
1.35
3.01
4.5
6.5
1.22
1.22
mmol/l
0.91
184
1516
33
179
1.90
2.88
1.9
2.7
48.71
102.47
ng/l
2.34
28
160
131
997
1.41
2.85
1.8
1.9
0.76
0.87
mg/l
0.38
93
741
22
108
2.08
2.55
1.1
1.1
4.13
7.02
u/ml
0.44
14
44
331
2940
1.30
2.43
4.5
3.8
343.67
413.37
e6/l
—
6
35
276
2398
1.29
2.39
2.7
2.8
71.21
85.51
ug/l
1.30
265
2251
55
367
1.55
2.33
2.5
2.7
—
—
—
0
0
23
123
1.91
2.14
1.1
1.1
9.88
4.86
u/ml
0.32
13
46
28
161
1.78
2.10
1.7
1.7
0.03
0.05
iu/ml
—
10
25
156
1278
1.30
2.06
3.1
2.5
55.64
55.70
u/l
0.01
146
1193
184
1542
1.28
2.05
4.4
4.7
37.37
36.95
g/l
0.49
165
1459
95
727
1.37
2.00
1.5
1.6
464.16
53437928.63
pmol/l
1.57
83
640
127
1021
1.31
1.92
2.3
2.1
2.71
2.80
mg/l
0.20
116
880
24
136
1.80
1.90
1.1
1.1
1.20
3.87
u/ml
—
10
35
150
1240
1.28
1.84
2.2
2.3
—
—
—
0
0
13
260
0.49
1.83
1.2
1.4
—
—
—
0
0
68
501
1.41
1.80
1.5
1.6
1251.86
1181.97
nmol/l
0.20
51
383
139
1143
1.29
1.77
2.1
2.1
—
—
—
0
0
25
148
1.72
1.73
1.6
2.0
—
—
—
0
0
5
13
3.87
1.72
1.0
1.0
—
—
—
0
0
77
585
1.37
1.71
2.7
2.5
2.44
2.42
mmol/l
0.92
68
516
186
1601
1.24
1.60
4.1
6.1
1.22
1.22
mmol/l
0.41
165
1471
12
57
2.13
1.56
2.1
1.5
—
—
—
0
0
13
65
2.02
1.49
1.2
1.1
—
—
—
0
0
179
1546
1.23
1.48
3.7
3.0
31.13
30.44
u/l
0.10
170
1480
24
148
1.65
1.46
1.3
1.1
—
—
—
0
0
99
800
1.29
1.45
1.4
1.4
21.05
20.80
nmol/l
0.07
86
699
6
24
2.52
1.30
1.2
1.1
1682.00
1793.75
miu/ml
—
6
24
69
539
1.32
1.30
1.9
2.0
—
—
—
0
0
454
4329
1.23
1.25
11.0
9.0
93.52
93.04
ml/min/173m2
0.21
390
3456
129
1097
1.23
1.23
1.7
1.6
1.30
1.40
mmol/l
0.81
106
948
8
37
2.18
1.22
1.1
1.2
—
—
—
0
0
35
248
1.44
1.20
1.5
1.6
—
—
—
0
0
20
125
1.62
1.19
1.4
1.9
—
—
—
0
0
48
361
1.36
1.18
1.0
1.0
—
—
—
0
0
158
1378
1.20
1.17
3.5
2.9
—
—
—
0
0
23
150
1.56
1.16
1.3
1.1
—
—
—
0
0
21
134
1.59
1.16
1.5
1.2
2.32
6.90
u/ml
—
5
22
556
5458
1.60
1.15
17.4
15.3
256.39
261.85
e9/l
1.37
550
5346
11
58
1.91
1.12
1.5
1.3
—
—
—
0
0
24
160
1.52
1.11
1.1
1.1
3.04
1.92
u/ml
0.23
14
58
403
3822
1.18
1.06
4.2
4.0
14.28
14.38
pmol/l
0.40
378
3532
556
5464
1.56
1.06
17.4
15.3
4.54
4.55
e12/l
0.18
550
5343
45
344
1.33
1.02
1.8
3.3
4.42
4.65
pmol/l
0.89
37
307
230
2094
1.16
1.01
4.8
5.8
10.03
10.44
umol/l
0.32
220
1979
7
35
2.01
1.00
1.3
1.1
—
—
—
0
0
145
1273
1.19
0.99
2.8
3.1
2.35
2.36
mmol/l
0.28
131
1154
11
62
1.79
0.94
1.1
1.1
—
—
—
0
0
429
4107
1.18
0.93
3.6
3.7
—
—
—
0
0
47
367
1.31
0.93
1.1
1.4
24.43
24.23
iu/l
0.01
42
313
60
484
1.27
0.93
2.3
2.5
25.14
25.03
%
0.02
50
422
119
1034
1.19
0.92
3.8
3.6
91.46
96.90
%
1.51
114
1003
255
2358
1.15
0.88
3.9
4.6
6.15
6.37
mmol/l
0.92
231
2135
459
4429
1.18
0.86
4.9
4.6
1.81
2.05
mu/l
0.43
442
4154
41
320
1.30
0.83
14.6
13.2
1.29
1.17
inr
0.33
15
55
70
584
1.23
0.83
3.6
3.9
1.65
2.19
ug/l
0.47
64
534
15
97
1.56
0.82
1.1
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
2.8
—
—
—
0
0
13
82
1.60
0.78
1.6
1.4
—
—
—
0
0
229
2116
1.14
0.78
4.4
3.9
—
—
—
0
0
50
608
0.81
0.74
2.9
2.4
1.12
1.02
e6/l
0.12
28
320
513
5015
1.22
0.73
10.6
8.5
25.43
26.39
u/l
0.65
503
4875
17
118
1.45
0.70
2.8
2.3
8.12
10.15
mg/l
0.85
17
109
154
1399
1.14
0.68
1.7
1.7
104.31
97.76
pmol/l
0.84
72
731
128
1149
1.15
0.67
1.6
1.5
—
—
—
0
0
7
43
1.64
0.67
1.0
1.1
—
—
—
0
0
56
469
1.22
0.66
3.3
3.6
24.46
21.90
%
0.54
16
192
15
103
1.47
0.65
1.3
1.8
—
—
—
0
0
25
325
0.76
0.64
1.8
2.3
75.55
76.30
ml/min/173m2
0.04
11
132
47
390
1.22
0.61
1.3
1.3
—
—
—
0
0
5
30
1.67
0.61
1.6
3.1
—
—
—
0
0
46
382
1.22
0.60
2.4
2.3
36.97
33.11
u/l
0.17
39
324
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
30.29
—
0
22
118
1064
1.14
0.59
2.4
2.1
134.73
227.46
u/l
0.84
112
1016
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
12
81
1.49
0.57
2.5
2.8
23.38
24.14
mmol/l
—
6
73
474
4625
1.14
0.57
10.9
10.8
3.90
3.92
mmol/l
1.12
464
4485
19
142
1.35
0.55
1.6
1.8
—
—
—
0
0
113
1023
1.13
0.53
3.6
3.0
1.02
1.02
kg/l
0.34
23
125
472
4612
1.13
0.52
10.8
10.8
139.66
139.65
mmol/l
0.05
464
4485
22
280
0.78
0.51
1.7
2.2
25.40
37.24
u/ml
0.49
22
267
6
41
1.47
0.50
3.5
1.9
—
—
—
0
0
35
289
1.22
0.50
1.3
1.3
228.70
258.89
miu/ml
0.17
14
143
33
271
1.23
0.49
2.4
1.9
—
—
—
0
0
70
618
1.15
0.48
1.7
1.8
—
—
—
0
0
7
46
1.53
0.48
2.0
1.4
—
—
—
0
0
157
1459
1.10
0.47
1.7
1.7
—
—
—
0
0
105
1150
0.89
0.46
2.8
3.2
8.81
8.35
mmol/l
0.34
95
1003
9
130
0.69
0.43
1.2
1.3
—
—
—
0
0
18
228
0.78
0.42
2.1
4.1
1.49
1.41
mmol/l
0.05
13
162
51
581
0.87
0.41
3.1
2.5
2.58
4.03
e6/l
1.20
28
292
14
105
1.34
0.41
2.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
21
260
0.80
0.41
2.4
1.8
2.35
3.40
mg/l
0.66
15
179
10
71
1.42
0.39
1.4
1.4
—
—
—
0
0
10
71
1.42
0.39
1.4
1.4
—
—
—
0
0
5
35
1.43
0.39
1.2
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
9
67
1.35
0.38
1.2
1.1
—
—
—
0
0
438
4467
0.92
0.36
3.8
3.6
4.77
4.79
mmol/l
0.16
415
4231
21
171
1.24
0.36
1.9
2.1
—
—
—
0
0
84
769
1.11
0.35
1.8
1.9
—
—
—
0
0
91
986
0.91
0.34
2.0
2.5
308.67
5334.63
umol/l
3.29
85
886
420
4285
0.93
0.33
3.3
3.3
1.21
1.25
mmol/l
0.60
398
4035
437
4451
0.92
0.33
3.6
3.6
1.47
1.49
mmol/l
0.37
414
4200
14
110
1.28
0.32
1.6
1.3
297.50
324.82
ug/g
—
8
60
349
3399
1.07
0.31
3.0
3.0
32.54
38.04
u/l
1.59
338
3259
115
1077
1.08
0.31
3.5
2.7
0.14
0.43
e6/l
2.18
93
807
18
147
1.23
0.31
2.2
2.2
6.16
4.80
umol/l
0.23
11
105
7
99
0.70
0.31
1.1
1.4
—
—
—
0
0
25
292
0.85
0.30
3.4
4.3
3.31
22.31
ug/l
0.68
16
232
31
269
1.16
0.30
5.5
3.1
1.22
1.23
mmol/l
0.20
26
231
7
56
1.25
0.29
1.0
1.1
—
—
—
0
0
94
875
1.09
0.29
1.3
1.3
10.92
8.00
u/ml
0.15
41
372
8
106
0.75
0.29
2.4
1.8
0.16
3.77
ug/l
—
8
101
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
95
888
1.08
0.27
1.4
1.3
23.04
28.20
iu/ml
0.29
27
284
27
310
0.86
0.27
1.8
1.7
—
—
—
0
0
5
74
0.67
0.26
4.4
2.4
551.20
121.02
ug/min
—
5
46
9
77
1.17
0.24
3.3
2.1
126.00
134.70
g/l
—
9
57
39
351
1.12
0.24
3.4
3.9
219.05
235.51
u/l
0.67
39
336
44
484
0.90
0.24
1.3
1.3
84.16
148.79
iu/ml
0.83
21
200
437
4305
1.06
0.23
3.7
3.5
5.56
5.70
mmol/l
1.63
416
4004
5
38
1.32
0.23
1.4
1.6
—
—
—
0
0
5
40
1.25
0.22
2.2
3.2
19.40
41.05
u/ml
—
5
40
5
41
1.22
0.22
1.4
1.5
0.90
0.99
g/l
—
5
41
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
465
4702
0.94
0.20
12.2
11.1
40.34
40.46
%
0.14
396
3877
6
49
1.23
0.20
3.5
1.7
—
—
—
0
0
39
356
1.10
0.19
2.2
1.9
—
—
—
0
0
40
366
1.10
0.19
2.2
1.9
—
—
—
0
0
47
434
1.09
0.19
2.1
2.1
2331.37
4163.31
u/l
0.38
15
173
7
59
1.19
0.18
1.7
1.4
—
—
—
0
0
76
720
1.06
0.17
3.1
2.9
460.98
698.39
ng/l
0.62
62
579
54
575
0.93
0.16
1.4
1.5
—
—
—
0
0
10
83
1.21
0.15
1.1
1.2
—
—
—
0
0
7
86
0.81
0.14
3.3
1.9
—
—
—
0
0
11
93
1.19
0.14
1.1
1.1
—
—
—
0
0
7
90
0.78
0.14
1.0
1.1
—
—
—
0
0
12
103
1.17
0.14
1.7
1.3
—
1.28
—
0
5
27
248
1.09
0.13
1.7
1.7
—
—
—
0
0
22
241
0.91
0.12
8.2
7.7
25.10
24.98
mmol/l
0.06
22
241
105
1016
1.04
0.12
1.9
2.0
—
—
—
0
0
20
219
0.91
0.11
1.5
1.5
—
—
—
0
0
29
311
0.93
0.11
2.3
4.9
0.82
1.88
mmol/l
1.18
21
248
447
4503
0.97
0.10
4.0
3.9
2.92
2.89
mmol/l
0.23
426
4238
24
222
1.08
0.10
1.3
1.5
—
—
—
0
0
24
222
1.08
0.10
1.3
1.5
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
12
106
1.13
0.10
1.3
1.0
3.93
1.96
u/ml
—
7
54
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
37
351
1.06
0.08
2.2
2.6
0.76
0.67
ug/l
0.22
16
202
6
58
1.03
0.08
1.0
1.2
—
—
—
0
0
31
328
0.94
0.08
1.5
1.5
—
—
—
0
0
26
277
0.94
0.08
1.4
1.6
—
—
—
0
0
6
72
0.83
0.07
1.8
1.7
—
—
—
0
0
53
511
1.04
0.07
2.1
2.8
6.87
7.01
umol/l
0.02
40
430
7
83
0.84
0.07
1.0
1.1
122.43
116.92
%
—
7
76
132
1296
1.02
0.07
2.7
2.8
13.18
25.79
ng/l
2.36
54
664
8
93
0.86
0.06
3.1
1.8
—
—
—
0
0
12
132
0.91
0.06
1.0
1.1
—
—
—
0
0
46
474
0.97
0.04
4.4
6.5
1.05
1.06
mmol/l
0.09
41
446
10
91
1.10
0.04
3.0
1.8
223.80
193.83
pmol/l
—
10
86
15
160
0.94
0.04
1.4
1.4
—
—
—
0
0
29
300
0.96
0.03
1.4
1.4
—
—
—
0
0
15
142
1.06
0.02
2.3
1.5
—
—
—
0
0
29
299
0.97
0.02
1.4
1.4
—
—
—
0
0
29
299
0.97
0.02
1.4
1.4
—
—
—
0
0
29
299
0.97
0.02
1.4
1.4
—
—
—
0
0
92
930
0.99
0.02
3.5
4.3
7.90
11.65
mg/mmol
0.36
62
594
390
3889
1.01
0.02
4.3
4.4
36.73
38.15
mmol/mol
4.12
371
3678
32
312
1.03
0.02
5.3
10.6
0.89
1.00
mmol/l
0.05
22
251
18
173
1.04
0.01
1.8
1.8
—
—
—
0
0
13
136
0.95
0.00
5.2
5.5
1.21
1.34
mg/l
0.35
13
125
16
164
0.97
0.00
1.1
1.2
—
—
—
0
0
10
97
1.03
0.00
1.5
1.2
—
—
—
0
0
21
206
1.02
0.00
1.4
1.4
—
—
—
0
0
38
376
1.01
0.00
1.3
1.4
—
—
—
0
0
15
152
0.99
0.00
3.3
2.9
182.13
172.68
%
0.16
15
146
60
603
0.99
0.00
1.4
1.6
—
—
—
0
0
14
139
1.01
0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
6
63
0.95
0.00
1.0
1.1
—
—
—
0
0
5
50
1.00
0.00
3.8
1.7
—
—
—
0
0
7
70
1.00
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
1.22
—
0
8
0
8
0.00
0.00
0.0
5.1
—
—
—
0
0
6
65
0.92
0.00
3.3
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
2.09
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
8
84
0.95
0.00
4.1
3.5
14.52
27.65
mg/l
—
8
55
0
6
0.00
0.00
0.0
1.0
—
15.67
—
0
6
7
73
0.96
0.00
2.6
2.5
—
—
—
0
0
6
63
0.95
0.00
3.5
1.9
—
—
—
0
0
5
56
0.89
0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
0.80
—
0
5
6
61
0.98
0.00
1.0
1.6
—
9.78
—
0
5
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_ASYMMETRY_JAW and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ASYMMETRY_JAW | 0.842 [0.65, 1.1] | 0.204 |
| Birth year | 0.99 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 2066 males with K11_ASYMMETRY_JAW died.
Mortality risk
Mortality risk for people of age
years, who have K11_ASYMMETRY_JAW.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.188% |
| 5 | No data | 1.004% |
| 10 | No data | 2.642% |
| 15 | No data | 5.127% |
| 20 | No data | 8.709% |
Relationships between endpoints
↥Index endpoint: K11_ASYMMETRY_JAW – Asymmetry of jaw
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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