No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
575 |
4. Check minimum number of eventsNone |
575 |
5. Include endpointsNone |
575 |
6. Filter based on genotype QC (FinnGen only) |
558 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
Asymmetry of jaw
based on the number of shared cases.
Similar with more cases:
- Dentofacial anomalies [including malocclusion]
- Diseases of oral cavity, salivary glands and jaws
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5892 | 3581 | 2294 |
| Only index persons | 5631 | 3444 | 2187 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.06 |
| Only index persons | 0.11 | 0.13 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 19.42 | 20.42 | 17.77 |
| Only index persons | 20.03 | 21.27 | 18.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 558 | 419 | 139 |
| Unadjusted period prevalence (%) | 0.13 | 0.15 | 0.06 |
| Median age at first event (years) | 32.33 | 31.27 | 35.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 575
- Matched controls
- 5750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.10
ICD-10 Finland
Asymmetry of jaw
+∞
307.7
574
*
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
207.7
307.7
211
16
K07.13
ICD-10 Finland
Retrognaty, mandibular
65.6
307.7
218
53
SBB10
NOMESCO Finland
Dental impressions
17.6
278.6
328
403
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
27.0
257.5
196
108
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
22.0
256.0
221
159
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
16.5
241.8
261
275
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
20.6
235.3
207
153
EB1MA
NOMESCO Finland
Cephalometry with X-ray
21.3
220.3
186
126
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
18.1
210.7
197
161
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
18.6
204.7
186
144
K07.24
ICD-10 Finland
Open bite
40.5
201.8
127
40
SJC10
NOMESCO Finland
Orthodontic band in one tooth
20.2
196.9
168
115
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
17.9
194.8
180
143
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
26.6
183.1
134
65
EEC05
NOMESCO Finland
Le Fort I osteotomy
346.3
158.1
153
6
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
14.5
156.9
161
150
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
13.9
151.9
160
155
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
60.9
140.4
79
15
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
17.2
131.8
117
84
SAA04
NOMESCO Finland
Special examination of mouth
10.1
129.1
175
238
K07.60
ICD-10 Finland
Snapping jaw
9.9
122.5
168
231
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
12.3
104.0
113
112
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
247.3
102.2
102
5
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
12.2
100.2
109
108
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
6.3
95.5
222
525
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
10.2
94.7
119
144
K07.14
ICD-10 Finland
Retrognaty, maxillary
145.5
93.3
97
8
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
13.7
89.7
89
76
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
11.3
89.3
102
108
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
161.2
80.4
83
6
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
9.9
77.3
97
116
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
6.3
74.4
150
304
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
7.2
73.6
125
213
EBB10
NOMESCO Finland
Insertion of dental implant
23.7
70.9
52
24
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
36.6
69.6
44
13
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
136.8
68.6
72
6
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
13.2
68.2
68
58
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
195.5
67.6
69
*
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
7.6
65.2
102
158
K07.23
ICD-10 Finland
Deep bite
8.4
63.7
90
124
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
239.5
63.5
64
*
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
17.6
63.2
53
33
SAA03
NOMESCO Finland
Extended examination of mouth
4.4
59.6
408
2064
SXC05
NOMESCO Finland
Other oral or dental procedure
5.3
55.9
135
317
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
17.8
55.3
46
28
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
84.8
55.2
61
8
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
7.2
55.1
89
142
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
22.6
53.7
40
19
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
279.2
51.0
51
*
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
15.7
50.7
45
31
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
17.1
47.3
40
25
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
5.6
44.8
95
197
WZC00
NOMESCO Finland
Treatment plan or consultation
3.3
43.5
316
1554
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
11.8
42.9
45
41
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
5.8
42.7
85
166
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
10.4
40.9
47
49
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
71.2
40.7
46
7
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
5.3
40.0
89
192
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
5.8
37.3
73
140
SPC10
NOMESCO Finland
Standard dental crown
13.7
36.9
35
27
EDC30
NOMESCO Finland
Genioplasty
368.6
35.3
35
*
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
7.4
33.2
50
73
Z3229
NOMESCO Finland
Other healthcare associate professional
4.7
30.4
77
184
SPC20
NOMESCO Finland
Implant borne crown
35.8
29.1
37
11
K01.0
ICD-10 Finland
Embedded teeth
6.6
28.8
48
78
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
6.2
28.5
51
89
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
10.9
28.2
31
30
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
10.9
28.2
31
30
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.6
27.2
329
1961
ZXA10
NOMESCO Finland
Bilateral
3.2
26.6
130
487
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.5
26.3
68
165
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
30.0
25.7
34
12
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
70.6
24.0
27
*
L01BA01
ATC
methotrexate; systemic
6.2
23.4
41
70
K00.00
ICD-10 Finland
Hypodontia
7.5
22.7
33
46
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
22.5
22.4
32
15
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
228.3
21.7
22
*
EB1WA, ,
NOMESCO Finland
21.8
21.5
31
15
P01BA02
ATC
hydroxychloroquine; oral
3.6
20.9
76
235
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
21.0
20.6
30
15
EBA10
NOMESCO Finland
Operative extraction of tooth
2.5
20.0
157
744
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
18.5
19.8
30
17
EBB15
NOMESCO Finland
Insertion of dental implant abutment
25.7
19.7
27
11
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
19.5
66
194
SXC03
NOMESCO Finland
Other oral or dental procedure
15.5
19.1
31
21
L04AX03
ATC
methotrexate; systemic
3.2
19.0
84
293
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.1
18.8
89
323
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
8.0
18.8
26
34
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
6.7
18.5
30
47
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.3
18.5
75
248
K07.4
ICD-10 Finland
Malocclusion, unspecified
6.1
18.1
32
55
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
54.4
18.1
21
*
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
98.1
17.7
19
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
17.2
172
900
ZXE20
NOMESCO Finland
More than three and less than five hours
2.9
16.8
89
344
EEC02
NOMESCO Finland
Rapid expansion of maxilla
92.8
16.6
18
*
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
19.2
16.1
24
13
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
7.1
15.8
24
35
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
87.5
15.6
17
*
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
39.2
15.5
19
5
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
5.5
15.3
30
57
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.3
14.8
25
41
SJE90
NOMESCO Finland
Orthodontic finishing
17.5
14.4
22
13
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.1
14.2
40
103
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.1
14.2
62
214
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.3
13.9
56
184
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
13.9
187
1087
R06.5
ICD-10 Finland
Mouth breathing
2.9
13.4
66
244
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.4
13.3
104
485
J01CE02
ATC
phenoxymethylpenicillin; oral
2.1
12.6
440
3501
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
71.5
12.6
14
*
A07EC01
ATC
sulfasalazine; oral, rectal
3.0
12.6
59
212
G50.1
ICD-10 Finland
Atypical facial pain
6.4
12.5
21
34
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
132.8
12.5
13
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.1
12.4
35
90
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
14.8
12.3
20
14
Z01.2
ICD-10 Finland
Dental examination
1.9
12.1
320
2306
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
66.3
11.6
13
*
K07.0
ICD-10 Finland
Major anomalies of jaw size
66.3
11.6
13
*
SPB20
NOMESCO Finland
Temporary bridge
23.5
11.6
16
7
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
17.5
11.3
17
10
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
20.5
11.2
16
8
OIKK, ,
NOMESCO Finland
3.0
11.2
52
186
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
10.9
208
1341
K07.61
ICD-10 Finland
Cracking jaw joint
4.0
10.8
31
81
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
28.6
10.8
14
5
TEG00
NOMESCO Finland
Punction of mandibular joint
61.2
10.7
12
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
10.6
195
1240
ZXE00
NOMESCO Finland
One hour or less
1.8
10.6
230
1541
EGC30
NOMESCO Finland
Prosthetic replacement of mandibular joint
112.0
10.5
11
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
10.4
10
*
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
+∞
10.4
10
*
EB1TW
NOMESCO Finland
3D modelling of dentition
33.2
10.4
13
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.7
10.1
32
90
5241A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Anomalies of relationship of jaw to cranial base
40.8
10.0
12
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
10.0
109
579
Z2221
NOMESCO Finland
Medical doctor
1.9
9.9
168
1040
SAA02
NOMESCO Finland
Basic examination of mouth
2.0
9.8
457
3811
L04AB01
ATC
etanercept; parenteral
5.4
9.7
19
36
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
+∞
9.4
9
*
G47.3
ICD-10 Finland
Sleep apnoea
2.0
9.2
115
641
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
15.9
9.1
14
9
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
37.3
9.0
11
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.6
9.0
30
87
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
19.0
9.0
13
7
ZXD20
NOMESCO Finland
Day surgery
2.2
8.8
81
401
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
8.7
54
225
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.2
8.5
33
106
L88
ICPC
Rheumatoid/seropositive arthritis
3.4
8.5
30
91
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
+∞
8.4
8
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.9
8.2
39
141
Z3226
NOMESCO Finland
Physiotherapist
2.0
8.2
102
565
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
17.5
8.1
12
7
Q67.0
ICD-10 Finland
Facial asymmetry
33.9
8.1
10
*
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
33.9
8.1
10
*
R4110
NOMESCO Finland
Physiotherapy
1.8
8.1
144
898
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
6.7
7.9
19
29
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
7.9
155
992
M01AE02
ATC
naproxen; oral, rectal
1.7
7.7
357
2857
N03AE01
ATC
clonazepam; systemic
3.0
7.7
34
118
ZZH22
NOMESCO Finland
Graft of patients own bone, block
18.7
7.6
11
6
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
6.3
7.6
19
31
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.3
7.5
28
88
H02AB06
ATC
prednisolone; systemic
1.6
7.4
237
1724
4347
FHL
Osteotomy of the upper jaw
81.1
7.4
8
*
K07.09
ICD-10 Finland
Anomaly in the size of the jaws UNS
+∞
7.3
7
*
ECA50
NOMESCO Finland
Periodontal flap surgery
10.2
7.1
13
13
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
7.0
190
1322
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.0
220
1590
UDC00
NOMESCO Finland
Ear microscopy
2.4
6.9
48
211
G43.9
ICD-10 Finland
Migraine, unspecified
2.2
6.8
57
271
K07.6
ICD-10 Finland
Temporomandibular joint disorders
7.3
6.7
15
21
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
7.3
6.7
15
21
R51.81
ICD-10 Finland
Facial pain NOS
3.8
6.7
20
54
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
7.9
6.6
14
18
RT160, ,
NOMESCO Finland
12.4
6.6
11
9
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
12.4
6.6
11
9
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.6
6.6
224
1644
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
70.6
6.4
7
*
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
18.3
6.3
9
5
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
18.3
6.3
9
5
ZXA00
NOMESCO Finland
Right side
1.8
6.3
108
662
7143D
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[OLIGARTHRITIS JUVENILIS]
+∞
6.3
6
*
SDA03
NOMESCO Finland
Periodontal treatment
1.6
6.3
242
1824
ZYC01
NOMESCO Finland
Remote contact by phone
2.4
6.2
44
195
H20.1
ICD-10 Finland
Chronic iridocyclitis
7.8
6.1
13
17
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
6.1
54
263
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.2
6.1
50
236
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.4
6.1
21
63
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
398
3346
1.62
6.43
5.3
3.8
8.40
9.32
mm/h
1.19
385
3132
327
2697
1.49
5.20
8.8
8.3
3.65
3.97
e9/l
2.32
298
2374
290
2349
1.47
4.96
7.2
5.7
31.11
30.04
%
1.13
278
2225
288
2334
1.47
4.89
3.5
3.0
0.00
0.01
estimate
0.80
76
469
232
1810
1.47
4.75
3.6
3.0
—
—
—
0
0
284
2306
1.46
4.72
3.5
3.0
0.00
0.00
estimate
0.50
77
498
284
2309
1.45
4.67
4.7
4.2
0.00
0.00
estimate
0.50
79
487
284
2315
1.45
4.57
7.0
5.5
54.61
55.82
%
1.20
272
2184
166
1234
1.49
4.25
3.9
3.2
0.00
0.01
estimate
1.34
76
482
40
205
2.02
4.03
1.5
1.7
—
—
—
0
0
374
3274
1.41
3.68
6.9
6.7
71.57
77.11
u/l
2.81
363
3098
115
828
1.49
3.39
2.9
2.3
4.96
8.37
e6/l
1.98
108
739
513
4799
1.64
3.38
12.4
10.5
18.07
19.93
mg/l
0.75
399
3625
20
431
0.44
3.31
2.7
4.8
—
—
—
0
0
23
103
2.28
3.26
4.8
3.8
55.13
56.61
%
0.28
23
103
90
624
1.52
3.17
3.1
3.3
191.84
419.37
ng/l
0.58
50
369
171
1353
1.38
2.97
1.4
1.4
1.37
2.03
u/ml
0.49
48
370
222
1842
1.33
2.80
2.3
2.3
76.53
73.12
nmol/l
1.07
205
1699
33
181
1.87
2.80
1.7
2.7
56.79
102.65
ng/l
1.59
28
162
217
1796
1.33
2.78
4.5
6.6
1.22
1.22
mmol/l
0.86
185
1530
104
764
1.44
2.75
3.1
2.3
145.83
100.10
ug/g
0.51
83
588
22
105
2.14
2.72
1.1
1.1
4.14
6.13
u/ml
0.29
14
43
129
996
1.38
2.57
1.9
1.9
0.77
0.88
mg/l
0.38
92
739
182
1492
1.32
2.44
7.5
7.8
1.12
1.09
inr
0.32
85
508
55
364
1.57
2.41
2.5
2.7
—
—
—
0
0
331
2950
1.29
2.32
4.5
3.8
343.67
422.81
e6/l
—
6
36
275
2397
1.28
2.29
2.7
2.8
71.19
85.52
ug/l
1.30
264
2249
23
120
1.95
2.29
1.1
1.1
9.19
4.16
u/ml
0.35
14
59
10
35
2.89
2.21
1.0
1.4
66.40
70.20
umol/l
—
10
35
28
159
1.80
2.17
1.5
1.6
0.03
0.05
iu/ml
—
10
24
24
134
1.83
1.98
1.1
1.1
1.05
2.53
u/ml
0.96
13
67
155
1279
1.29
1.93
3.1
2.5
55.67
57.54
u/l
0.29
146
1194
94
725
1.35
1.88
1.5
1.6
465.10
53605444.84
pmol/l
1.57
82
638
13
260
0.49
1.83
1.2
1.4
—
—
—
0
0
5
12
4.19
1.82
1.0
1.0
—
—
—
0
0
126
1019
1.30
1.82
2.3
2.1
2.71
2.81
mg/l
0.21
115
879
78
588
1.38
1.80
2.7
2.5
2.44
2.42
mmol/l
1.06
69
519
182
1544
1.26
1.80
4.5
4.9
37.33
36.96
g/l
0.43
163
1466
25
148
1.72
1.73
1.6
2.0
—
—
—
0
0
67
500
1.38
1.66
1.5
1.6
1252.58
1176.24
nmol/l
0.22
50
383
148
1243
1.26
1.58
2.2
2.3
—
—
—
0
0
186
1607
1.23
1.54
4.1
6.2
1.22
1.22
mmol/l
0.55
168
1481
137
1145
1.26
1.52
2.1
2.1
—
—
—
0
0
12
58
2.09
1.50
2.1
1.5
—
—
—
0
0
13
65
2.02
1.49
1.2
1.1
—
—
—
0
0
179
1546
1.23
1.48
3.7
3.1
31.16
30.48
u/l
0.10
170
1480
24
149
1.64
1.43
1.3
1.1
—
—
—
0
0
11
53
2.10
1.39
1.7
1.2
0.46
0.48
nmol/l
0.11
11
48
98
800
1.27
1.33
1.4
1.4
21.10
20.80
nmol/l
0.08
85
700
6
24
2.52
1.30
1.2
1.1
1682.00
1793.75
miu/ml
—
6
24
69
542
1.31
1.26
1.9
2.0
—
—
—
0
0
129
1098
1.23
1.22
1.7
1.6
1.30
1.40
mmol/l
0.78
106
949
24
157
1.55
1.19
1.1
1.1
2.85
4.00
u/ml
0.23
15
81
48
361
1.36
1.18
1.0
1.0
—
—
—
0
0
557
5467
1.60
1.16
17.3
15.3
256.35
261.84
e9/l
1.38
551
5355
21
134
1.59
1.16
1.5
1.2
2.32
6.90
u/ml
—
5
22
23
151
1.54
1.13
1.3
1.1
—
—
—
0
0
20
127
1.60
1.13
1.4
1.9
—
—
—
0
0
11
58
1.91
1.12
1.5
1.3
—
—
—
0
0
454
4343
1.22
1.12
11.0
9.0
93.52
93.08
ml/min/173m2
0.19
390
3474
557
5473
1.57
1.07
17.3
15.3
4.54
4.55
e12/l
0.17
551
5352
157
1379
1.19
1.07
3.5
3.0
—
—
—
0
0
45
343
1.34
1.03
1.8
3.3
4.42
4.65
pmol/l
0.94
38
306
556
5464
1.53
1.03
17.3
15.4
48.90
41.35
%
0.42
536
5223
403
3826
1.18
1.03
4.3
3.9
14.29
14.38
pmol/l
0.35
378
3536
34
248
1.39
1.02
1.6
1.6
—
—
—
0
0
7
35
2.01
1.00
1.3
1.1
—
—
—
0
0
232
2115
1.16
1.00
2.5
2.5
—
—
—
0
0
11
61
1.82
0.99
1.1
1.1
—
—
—
0
0
145
1274
1.18
0.98
2.8
3.1
2.35
2.36
mmol/l
0.25
134
1160
430
4114
1.18
0.96
3.5
3.7
—
—
—
0
0
7
37
1.90
0.94
1.1
1.2
—
—
—
0
0
229
2095
1.15
0.93
4.8
5.9
10.03
10.68
umol/l
0.56
219
1982
256
2361
1.15
0.93
3.9
4.6
6.15
6.37
mmol/l
0.94
232
2138
119
1037
1.19
0.89
3.8
3.7
91.36
96.91
%
1.55
114
1006
49
611
0.78
0.88
3.0
2.5
1.13
1.02
e6/l
0.11
27
323
6
31
1.95
0.84
1.5
1.2
187.83
180.58
pmol/l
—
6
31
70
584
1.23
0.83
3.6
3.9
1.65
2.19
ug/l
0.47
64
534
59
484
1.24
0.81
2.3
2.5
25.04
25.02
%
0.00
49
423
459
4435
1.17
0.81
4.9
4.6
1.81
2.05
mu/l
0.44
442
4159
0
24
0.00
0.79
0.0
1.9
—
29.18
—
0
24
0
25
0.00
0.79
0.0
2.9
—
—
—
0
0
15
98
1.54
0.79
1.1
1.1
—
—
—
0
0
13
82
1.60
0.78
1.6
1.4
—
—
—
0
0
129
1150
1.16
0.74
1.6
1.5
—
—
—
0
0
9
145
0.61
0.70
1.3
4.3
0.79
0.65
%
—
9
145
56
469
1.21
0.66
3.3
3.6
24.46
21.90
%
0.54
16
192
25
326
0.76
0.66
1.8
2.3
75.55
76.30
ml/min/173m2
0.04
11
132
15
103
1.47
0.65
1.3
1.8
—
—
—
0
0
153
1398
1.13
0.62
1.7
1.7
104.31
97.76
pmol/l
0.84
72
732
5
30
1.67
0.61
1.6
3.1
—
—
—
0
0
47
391
1.22
0.60
1.3
1.3
—
—
—
0
0
512
5019
1.18
0.60
10.6
8.5
25.45
26.38
u/l
0.62
502
4879
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
20
263
0.75
0.57
1.6
1.8
2.37
3.46
mg/l
0.70
15
183
19
142
1.35
0.55
1.6
1.8
—
—
—
0
0
474
4630
1.14
0.53
10.8
10.9
3.90
3.92
mmol/l
1.15
464
4491
9
133
0.67
0.52
1.2
1.3
—
—
—
0
0
113
1025
1.13
0.52
3.6
3.0
1.02
1.02
kg/l
0.34
23
127
50
583
0.84
0.52
3.1
2.6
2.63
3.98
e6/l
1.04
27
294
11
75
1.48
0.51
2.0
1.6
5.68
4.99
mmol/24h
0.23
11
64
45
381
1.20
0.50
2.4
2.3
37.34
33.02
u/l
0.19
38
323
117
1066
1.12
0.50
2.4
2.1
135.40
227.44
u/l
0.84
111
1018
6
41
1.47
0.50
3.5
1.9
—
—
—
0
0
22
278
0.78
0.49
1.7
2.2
25.40
37.39
u/ml
0.50
22
266
472
4617
1.12
0.48
10.7
10.8
139.66
139.65
mmol/l
0.05
464
4491
105
1153
0.89
0.48
2.8
3.3
8.81
8.31
mmol/l
0.38
95
1018
7
47
1.50
0.47
2.0
1.4
—
—
—
0
0
35
291
1.22
0.47
1.3
1.4
228.70
260.69
miu/ml
0.19
14
145
16
120
1.34
0.46
2.2
2.3
7.88
10.10
mg/l
0.92
16
111
70
624
1.14
0.43
1.6
1.8
—
—
—
0
0
33
276
1.21
0.43
2.4
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.00
—
0
10
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
10
71
1.42
0.39
1.4
1.4
—
—
—
0
0
10
71
1.42
0.39
1.4
1.4
—
—
—
0
0
14
106
1.33
0.39
2.0
1.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
19
151
1.27
0.39
2.2
2.5
5.83
6.40
umol/l
0.08
12
109
5
36
1.39
0.38
1.2
1.0
—
—
—
0
0
9
67
1.35
0.38
1.2
1.1
—
—
—
0
0
156
1467
1.09
0.37
1.7
1.7
—
—
—
0
0
5
37
1.35
0.37
1.4
1.5
—
—
—
0
0
419
4281
0.92
0.36
3.3
3.3
1.21
1.25
mmol/l
0.54
397
4031
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
19
233
0.81
0.35
2.3
4.3
1.67
1.42
mmol/l
0.16
14
166
438
4465
0.92
0.35
3.8
3.6
4.77
4.79
mmol/l
0.17
416
4236
21
172
1.23
0.34
1.8
2.1
—
—
—
0
0
94
871
1.09
0.32
1.3
1.3
10.92
8.04
u/ml
0.15
41
370
437
4449
0.93
0.31
3.6
3.6
1.48
1.49
mmol/l
0.34
415
4205
91
981
0.91
0.31
2.0
2.5
308.67
5312.70
umol/l
3.29
85
890
349
3399
1.07
0.31
3.0
3.0
32.54
38.04
u/l
1.59
338
3259
7
99
0.70
0.31
1.1
1.4
—
—
—
0
0
84
776
1.10
0.30
1.8
1.9
—
—
—
0
0
14
111
1.27
0.30
1.6
1.3
297.50
323.64
ug/g
—
8
61
25
292
0.85
0.30
3.4
4.3
3.31
22.31
ug/l
0.68
16
232
33
376
0.87
0.29
6.5
8.1
105.21
104.71
mmol/l
0.38
33
376
8
106
0.75
0.29
2.4
1.8
0.16
3.77
ug/l
—
8
101
31
270
1.16
0.28
5.5
3.1
1.22
1.23
mmol/l
0.20
26
232
48
433
1.12
0.27
2.0
2.2
2331.37
4006.32
u/l
0.34
15
174
27
309
0.87
0.26
1.8
1.7
—
—
—
0
0
5
75
0.66
0.26
4.2
2.3
551.20
118.49
ug/min
—
5
47
94
882
1.08
0.25
1.4
1.3
28.59
28.85
iu/ml
0.01
29
293
9
77
1.17
0.24
3.3
2.1
126.00
134.70
g/l
—
9
57
114
1080
1.07
0.24
3.5
2.7
0.14
0.43
e6/l
2.17
95
813
5
40
1.25
0.22
2.2
3.2
19.40
41.05
u/ml
—
5
40
28
248
1.14
0.22
1.7
1.7
—
—
—
0
0
5
41
1.22
0.22
1.4
1.5
0.90
0.99
g/l
—
5
41
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
39
354
1.11
0.21
3.4
3.9
219.05
235.51
u/l
0.67
39
339
0
12
0.00
0.21
0.0
1.0
—
2.24
—
0
7
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
436
4303
1.05
0.20
3.6
3.5
5.56
5.71
mmol/l
1.65
415
4002
6
50
1.20
0.19
3.5
1.7
—
—
—
0
0
25
223
1.13
0.18
1.4
1.5
—
—
—
0
0
25
223
1.13
0.18
1.3
1.5
—
—
—
0
0
39
358
1.10
0.18
2.2
1.9
—
—
—
0
0
40
368
1.09
0.18
2.2
1.9
—
—
—
0
0
7
61
1.15
0.17
1.7
1.4
—
—
—
0
0
5
66
0.76
0.17
2.4
1.8
—
—
—
0
0
5
66
0.76
0.17
2.4
1.8
—
—
—
0
0
45
484
0.92
0.17
1.3
1.3
114.95
143.14
iu/ml
0.23
22
199
106
1016
1.05
0.16
1.9
2.0
—
—
—
0
0
19
168
1.14
0.16
1.3
1.7
0.21
0.23
g/l
0.56
19
162
7
87
0.80
0.14
3.3
1.9
—
—
—
0
0
7
90
0.78
0.14
1.0
1.1
—
—
—
0
0
10
84
1.19
0.14
1.1
1.2
—
—
—
0
0
11
94
1.17
0.13
1.1
1.1
—
—
—
0
0
29
314
0.92
0.13
2.3
5.3
0.93
1.83
mmol/l
1.09
24
256
12
104
1.16
0.12
1.7
1.3
—
1.28
—
0
5
75
719
1.05
0.12
2.9
3.0
463.75
697.66
ng/l
0.60
61
579
20
219
0.91
0.11
1.5
1.5
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
12
106
1.13
0.10
1.3
1.0
3.93
1.96
u/ml
—
7
54
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
447
4501
0.97
0.09
4.0
3.9
2.91
2.89
mmol/l
0.20
427
4247
55
573
0.96
0.09
1.4
1.5
—
—
—
0
0
23
247
0.93
0.09
8.1
8.3
25.10
24.98
mmol/l
0.06
23
247
37
351
1.06
0.08
2.2
2.6
0.76
0.67
ug/l
0.22
16
202
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
6
58
1.03
0.08
1.0
1.2
—
—
—
0
0
5
62
0.80
0.08
1.0
1.1
—
—
—
0
0
5
64
0.78
0.08
3.2
2.1
—
—
—
0
0
31
327
0.95
0.07
1.5
1.5
—
—
—
0
0
6
74
0.81
0.07
1.8
1.7
—
—
—
0
0
7
83
0.84
0.07
1.0
1.1
122.43
116.09
%
—
7
76
8
94
0.85
0.06
3.1
1.8
—
—
—
0
0
15
161
0.93
0.05
1.4
1.4
—
—
—
0
0
23
242
0.95
0.05
2.1
4.2
5.10
5.11
kpa
0.02
23
236
13
140
0.93
0.04
5.2
6.1
1.21
1.33
mg/l
0.31
13
129
10
91
1.10
0.04
3.0
1.8
223.80
193.83
pmol/l
—
10
86
29
301
0.96
0.04
1.4
1.4
—
—
—
0
0
12
129
0.93
0.03
1.0
1.1
—
—
—
0
0
29
300
0.96
0.03
1.4
1.4
—
—
—
0
0
29
300
0.96
0.03
1.4
1.4
—
—
—
0
0
29
300
0.96
0.03
1.4
1.4
—
—
—
0
0
15
142
1.06
0.02
2.3
1.5
—
—
—
0
0
131
1298
1.01
0.02
2.6
2.8
13.26
25.77
ng/l
2.33
53
667
39
381
1.03
0.02
1.4
1.4
—
—
—
0
0
47
478
0.98
0.01
4.4
6.5
1.07
1.06
mmol/l
0.04
42
450
32
313
1.02
0.01
5.3
10.8
0.89
1.03
mmol/l
0.07
22
254
92
927
0.99
0.01
3.4
4.1
7.90
11.69
mg/mmol
0.37
62
591
52
514
1.01
0.00
2.1
2.9
6.94
7.01
umol/l
0.01
39
433
10
96
1.04
0.00
1.5
1.2
—
—
—
0
0
16
165
0.97
0.00
1.1
1.2
—
—
—
0
0
18
175
1.03
0.00
1.8
1.8
—
—
—
0
0
21
205
1.03
0.00
1.4
1.4
—
—
—
0
0
15
153
0.98
0.00
3.3
3.2
182.13
173.10
%
0.15
15
147
60
603
0.99
0.00
1.4
1.6
—
—
—
0
0
28
279
1.00
0.00
1.5
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
0.80
—
0
5
6
64
0.94
0.00
3.5
1.9
—
—
—
0
0
6
65
0.92
0.00
3.3
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
9.83
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
14
140
1.00
-0.00
1.3
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
75
0.93
-0.00
2.6
2.4
—
—
—
0
0
7
71
0.99
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
84
0.95
-0.00
4.1
3.5
14.53
27.65
mg/l
—
8
55
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
50
1.00
-0.00
3.8
1.7
—
—
—
0
0
5
56
0.89
-0.00
1.2
1.5
—
—
—
0
0
389
3890
1.00
-0.00
4.2
4.4
36.73
38.14
mmol/mol
4.07
370
3679
0
6
0.00
-0.00
0.0
2.8
—
1.82
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
15.67
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint K11_ASYMMETRY_JAW and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ASYMMETRY_JAW | 0.842 [0.65, 1.1] | 0.204 |
| Birth year | 0.99 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 2066 males with K11_ASYMMETRY_JAW died.
Mortality risk
Mortality risk for people of age
years, who have K11_ASYMMETRY_JAW.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.188% |
| 5 | No data | 1.004% |
| 10 | No data | 2.642% |
| 15 | No data | 5.127% |
| 20 | No data | 8.709% |
Relationships between endpoints
↥Index endpoint: K11_ASYMMETRY_JAW – Asymmetry of jaw
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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