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Benign neoplasm of thyroid gland

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_THYROID

thyroid carcinoma: A carcinoma arising from the thyroid gland. It is usually an adenocarcinoma and includes the following main subtypes: follicular, papillary, medullary, poorly differentiated, and anaplastic.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D34&
  • Hospital discharge: ICD-9 — 226
  • Hospital discharge: ICD-8 — 2261
  • Cause of death: ICD-10 — D34&
  • Cause of death: ICD-9 — 226
  • Cause of death: ICD-8 — 2261

2 out of 7 registries used, show all original rules.

1249

4. Check minimum number of events

None

1249

5. Include endpoints

None

1249

6. Filter based on genotype QC (FinnGen only)

1219

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasma benignum glandulae thyreoideae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7907 6229 1639
Only index persons 7326 5875 1451
Unadjusted period prevalence (%)
Whole population 0.15 0.18 0.05
Only index persons 0.18 0.22 0.06
Median age at first event (years)
Whole population 51.68 50.47 56.14
Only index persons 50.64 49.65 54.67

-FinnGen-

Key figures

All Female Male
Number of individuals 1219 942 277
Unadjusted period prevalence (%) 0.29 0.33 0.13
Median age at first event (years) 51.66 49.57 58.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1249
Matched controls
12490
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
11071.7
307.7
1015
*
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
76.4
307.7
554
129
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
53.3
307.7
279
67
2260A
ICD-9 Finland
Benign neoplasm of thyroid gland[NEOPLASMA BENIGNUM GLANDULAE THYREOIDEAE]
+∞
244.0
226
*
2504
FHL
Unilateral resection or enucleation
40.6
208.7
128
35
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
19.8
203.3
163
94
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
17.8
178.3
150
95
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
22.2
169.6
128
64
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
9.8
165.3
208
249
H03AA01
ATC
levothyroxine sodium; systemic
4.4
146.5
626
2322
104
Kela drug reimbursment
Thyroid insufficiency
6.3
141.1
277
541
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
21.2
139.7
107
55
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
11.7
124.2
133
126
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.4
116.6
216
395
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
12.6
113.4
115
100
BAA60
NOMESCO Finland
Total thyroidectomy
10.1
112.4
133
145
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
24.7
95.4
68
29
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
12.4
85.9
87
75
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
10.8
42.2
46
44
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
10.6
37.0
41
40
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
4.4
35.4
93
225
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
6.4
34.1
57
92
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.5
32.5
252
1162
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
30.8
27.3
36
12
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
24.9
24.5
34
14
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
31.7
23.8
31
10
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.1
22.9
103
357
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
23.4
22.7
32
14
BA1AE, ,
SPAT
8.5
22.3
29
35
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
21.2
20.0
29
14
BAA30
NOMESCO Finland
Excision of thyroid isthmus
40.8
19.5
24
6
T86
ICPC
Hypothyroidism/myxoedema
3.1
19.5
83
278
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
25.5
18.3
25
10
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
23.7
15.1
21
9
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
4.9
14.5
32
67
E03
ICD-10 Finland
Other hypothyroidism
2.4
14.3
105
466
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
34.4
13.5
17
5
E03.89
ICD-10 Finland
Other specified hypothyroidism
2.8
13.3
69
259
2506
FHL
Thyroidectomy
17.5
12.5
19
11
EP1AE, ,
SPAT
4.0
12.5
35
89
WZC30
NOMESCO Finland
Teaching
1.8
12.4
205
1224
WX402
NOMESCO Finland
General anaesthesia
1.7
12.1
262
1688
E04.8
ICD-10 Finland
Other specified nontoxic goitre
12.7
11.6
20
16
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
11.6
293
1964
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
11.2
317
2183
T72
ICPC
Benign neoplasm thyroid
15.6
10.8
17
11
ZX114
NOMESCO Finland
Intramuscular
4.0
10.8
30
76
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
10.3
459
3484
UKC02
NOMESCO Finland
Cystoscopy
1.8
9.8
171
1035
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
3.9
9.0
26
68
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
8.9
258
1777
106
Kela drug reimbursment
Hypoparathyroidism
10.1
8.5
16
16
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
8.4
432
3339
A02BC05
ATC
esomeprazole; systemic
1.4
8.3
501
3988
A11CC03
ATC
alfacalcidol; systemic
3.2
8.1
32
103
4CJ01, ,
NOMESCO Finland
17.3
8.1
12
7
SPAT1359
SPAT
Use of symptom diary
2.8
7.8
37
133
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
15.1
7.7
12
8
WX704
NOMESCO Finland
Intubation
1.9
7.4
96
530
Z00.0
ICD-10 Finland
General medical examination
1.5
7.4
227
1578
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
8.4
7.3
15
18
R01AD09
ATC
mometasone; nasal
1.4
7.3
545
4475
R13
ICD-10 Finland
Dysphagia
1.9
7.1
89
485
T71
ICPC
Malignant neoplasm thyroid
20.1
7.1
10
5
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
20.1
7.1
10
5
Q18.8
ICD-10 Finland
Other specified congenital malformations of face and neck
20.1
7.1
10
5
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
3.7
7.0
22
61
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.7
6.9
21
57
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
6.8
82
442
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
9.4
6.8
13
14
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
6.7
101
584
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
3.3
6.7
25
78
N02BE01
ATC
paracetamol; systemic, rectal
1.6
6.6
1092
10178
E83.51
ICD-10 Finland
Hypocalcemia
5.9
6.6
17
29
J02AC01
ATC
fluconazole; systemic
1.4
6.6
505
4140
E04
ICD-10 Finland
Other nontoxic goitre
10.1
6.5
12
12
XKD00
NOMESCO Finland
Uroflowmetry
1.7
6.5
121
743
N64.4
ICD-10 Finland
Mastodynia
2.4
6.5
41
171
J01FA09
ATC
clarithromycin; systemic
1.4
6.5
364
2834
A02BC01
ATC
omeprazole; systemic
1.4
6.4
318
2421
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
11.1
6.3
11
10
UJF32
NOMESCO Finland
Coloscopy
1.4
6.3
303
2297
E06
ICD-10 Finland
Thyroiditis
+∞
6.3
6
*
D44
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of endocrine glands
+∞
6.3
6
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.2
418
3348
D44.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Endocrine gland, unspecified
26.8
6.2
8
*
ZSB00
NOMESCO Finland
Procedure related to previous procedure classified in chapter B
26.8
6.2
8
*
RD211, ,
NOMESCO Finland
2.1
6.2
58
286
A12AA04
ATC
calcium carbonate; oral
3.5
6.2
20
57
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
6.3
6.2
15
24
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
7.7
6.1
13
17
UDC00
NOMESCO Finland
Ear microscopy
1.8
6.1
88
503
S04
ICPC
Lump/swelling localized
1.7
6.1
122
765
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
2.6
6.1
33
128
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
1.9
6.0
79
438
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
5.2
6.0
17
33
G45.4
ICD-10 Finland
Transient global amnesia
2.6
6.0
32
123

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
124
58
23.63
168.90
6.7
6.5
—
—
—
0
0
133
96
15.39
147.05
6.1
4.6
32.20
51.82
u/ml
0.63
45
30
196
305
7.44
123.87
1.4
1.2
—
—
—
0
0
205
679
3.42
50.23
4.5
3.2
4.44
4.48
pmol/l
0.20
187
593
1086
8532
3.09
41.84
7.3
4.2
15.52
14.76
pmol/l
16.23
1017
7747
747
5332
2.00
30.30
7.7
6.0
1.21
1.22
mmol/l
0.91
627
4529
1149
9986
2.88
24.22
8.4
5.0
1.77
2.20
mu/l
1.30
1075
9132
661
4839
1.78
21.61
6.0
5.3
1.21
1.22
mmol/l
1.40
613
4401
170
875
2.09
16.13
4.1
3.4
1.22
1.23
mmol/l
1.28
155
754
456
3210
1.66
15.62
4.4
3.7
7.39
7.40
ph
0.82
129
602
229
1361
1.84
14.17
1.3
1.3
—
—
—
0
0
583
4468
1.57
13.50
2.5
2.1
—
—
—
0
0
918
7950
1.58
11.30
4.6
4.2
12.21
12.37
mm/h
0.13
856
7342
151
848
1.89
11.04
2.9
3.4
67.29
80.91
ng/l
1.80
129
742
51
189
2.77
10.09
2.0
2.2
—
—
—
0
0
486
3762
1.48
9.74
2.8
3.4
2.34
2.36
mmol/l
3.71
423
3307
577
4630
1.46
9.55
2.5
2.3
79.48
78.46
nmol/l
0.40
527
4137
616
5022
1.45
9.28
2.6
2.5
—
—
—
0
0
158
954
1.75
9.08
1.5
1.4
—
—
—
0
0
174
1087
1.70
8.84
5.6
3.9
—
—
—
0
0
601
4954
1.41
8.11
6.4
6.1
—
—
—
0
0
129
780
1.73
7.36
1.2
1.2
103.29
143.26
iu/ml
0.61
56
307
131
815
1.68
6.74
3.8
3.7
0.44
0.71
%
1.07
41
242
916
8257
1.41
6.56
8.4
7.3
77.01
77.58
u/l
0.15
869
7755
622
5285
1.35
6.39
5.7
5.6
0.04
0.04
e9/l
0.11
546
4575
621
5276
1.35
6.38
5.7
5.6
0.56
0.57
e9/l
0.18
545
4565
134
853
1.64
6.31
3.9
3.9
0.10
0.12
%
0.08
43
241
699
6054
1.35
6.29
4.4
4.3
6.58
6.66
mmol/l
0.55
666
5638
1149
10870
1.71
6.26
16.9
15.5
139.85
139.66
mmol/l
1.84
1135
10587
632
5407
1.34
6.09
5.7
5.6
1.89
1.92
e9/l
0.14
568
4788
139
901
1.61
6.09
3.9
3.9
0.80
1.01
%
0.46
47
292
601
5104
1.34
6.09
6.0
5.8
27.81
28.07
%
0.22
559
4776
60
302
2.04
6.08
3.9
6.1
1.22
1.27
mmol/l
0.24
53
271
1150
10897
1.70
6.03
17.1
15.6
3.93
3.96
mmol/l
2.33
1135
10599
588
4984
1.34
6.00
6.3
6.0
8.49
8.45
%
0.12
548
4651
584
4960
1.33
5.82
5.9
5.7
2.82
2.79
%
0.09
543
4621
592
5039
1.33
5.81
5.8
5.6
57.26
57.16
%
0.07
552
4710
560
4733
1.33
5.75
15.2
14.1
1.24
1.23
inr
0.03
218
1349
565
4796
1.33
5.57
5.9
5.8
0.71
0.69
%
0.55
525
4452
24
84
2.89
5.37
1.2
1.1
—
—
—
0
0
416
3400
1.34
5.26
2.3
2.3
—
—
—
0
0
62
334
1.90
5.22
8.1
9.2
—
—
—
0
0
122
801
1.58
5.08
4.0
4.0
0.00
0.97
%
0.94
31
192
630
5474
1.30
5.08
6.0
5.8
0.19
0.19
e9/l
0.12
568
4803
1111
10538
1.49
4.68
15.3
13.7
20.82
22.25
mg/l
0.74
896
8281
132
903
1.52
4.59
4.7
3.8
—
—
—
0
0
321
2579
1.33
4.45
2.3
2.2
—
—
—
0
0
345
2816
1.31
4.25
4.8
4.1
0.00
0.00
estimate
1.34
149
971
538
4655
1.27
4.20
2.7
2.7
113.99
108.15
ug/l
0.27
489
4291
92
598
1.58
4.03
2.1
1.7
—
—
—
0
0
692
6190
1.26
4.03
9.3
8.9
4.04
4.04
e9/l
0.00
619
5421
24
99
2.45
3.98
1.1
1.2
—
—
—
0
0
396
3321
1.28
3.92
2.6
2.4
55.79
59.58
u/l
0.43
356
3066
13
32
4.09
3.90
1.9
1.8
—
—
—
0
0
216
1669
1.36
3.85
2.8
2.9
0.83
0.82
mmol/l
0.79
201
1567
527
4588
1.26
3.80
4.1
4.4
35.78
35.69
g/l
0.15
480
4268
1163
11208
1.55
3.76
11.7
10.4
24.33
24.77
u/l
0.51
1120
10822
1200
11657
1.75
3.69
23.3
20.4
253.60
255.80
e9/l
0.61
1170
11371
1200
11661
1.74
3.63
23.1
20.4
90.80
91.09
fl
1.67
1190
11499
1200
11664
1.73
3.58
23.2
20.5
6.51
6.69
e9/l
1.17
1167
11338
1200
11664
1.73
3.58
23.2
20.4
4.47
4.44
e12/l
1.59
1166
11342
1200
11664
1.73
3.58
23.1
20.3
30.13
30.25
pg
1.74
1190
11500
1199
11653
1.72
3.56
23.3
20.5
40.04
39.71
%
1.15
1117
10925
1200
11667
1.73
3.54
23.3
20.6
134.18
133.54
g/l
0.96
1190
11502
111
775
1.47
3.53
3.3
2.8
10.87
10.50
g/l
0.39
100
704
799
7351
1.24
3.30
4.9
4.4
—
—
—
0
0
1139
10969
1.44
3.28
15.2
13.0
—
—
—
0
0
36
191
1.91
3.27
2.0
3.1
—
—
—
0
0
24
109
2.23
3.26
3.0
2.6
—
—
—
0
0
358
3027
1.26
3.22
3.3
3.2
717.03
331.98
mg/l
0.49
199
1844
619
5553
1.23
3.21
6.7
5.9
11.08
10.86
umol/l
0.15
586
5270
31
158
1.99
3.16
2.0
3.3
2.15
1.31
%
0.40
26
141
37
201
1.87
3.14
3.5
3.4
3.95
4.25
e9/l
0.35
37
201
455
3965
1.23
3.09
3.9
3.5
35.11
42.87
ng/l
0.21
307
2691
280
2317
1.27
3.00
1.8
1.7
36087398.24
26611224.61
pmol/l
0.10
230
1909
37
205
1.83
2.97
1.9
3.8
2.44
2.82
mmol/l
0.50
25
145
363
3100
1.24
2.95
4.0
3.8
—
—
—
0
0
8
17
4.73
2.92
1.5
1.5
—
—
—
0
0
523
4650
1.21
2.86
10.9
9.1
0.00
0.00
e9/l
0.30
449
3799
372
3197
1.23
2.84
3.2
3.0
6.93
7.04
mmol/l
0.20
306
2697
371
3188
1.23
2.83
4.0
3.7
8.80
7.79
mg/mmol
0.15
203
1897
195
1552
1.30
2.83
1.2
1.2
—
—
—
0
0
37
209
1.79
2.81
3.7
3.7
56.84
58.57
%
0.40
37
209
101
727
1.42
2.78
2.6
2.9
4.15
5.28
e9/l
1.03
76
585
155
1206
1.33
2.65
1.3
1.3
—
—
—
0
0
240
1980
1.26
2.62
1.3
1.3
29.17
33.64
iu/ml
0.23
88
663
10
30
3.35
2.60
1.9
1.6
—
—
—
0
0
61
404
1.54
2.56
2.1
2.0
1.01
2.07
ug/l
0.70
53
357
337
2901
1.22
2.49
1.6
1.6
1.28
1.35
mmol/l
1.18
275
2437
1074
10324
1.29
2.49
4.8
4.6
5.89
5.90
mmol/l
0.10
970
9383
312
2678
1.22
2.36
3.9
4.0
—
—
—
0
0
763
7106
1.19
2.33
5.1
4.7
68.60
1998.23
e6/l
—
5
99
85
616
1.41
2.29
1.7
1.7
1.28
1.42
g/l
0.30
78
562
28
156
1.81
2.27
1.6
1.3
0.62
0.62
nmol/l
0.00
28
148
34
201
1.71
2.26
4.1
3.6
156.04
1830.35
u/ml
0.74
27
190
279
2388
1.22
2.16
1.2
1.3
0.92
1.51
u/ml
1.01
80
633
1084
10469
1.27
2.15
4.5
4.4
4.72
4.75
mmol/l
0.35
985
9677
70
496
1.44
2.15
3.0
2.8
0.23
0.21
e6/l
0.09
70
479
327
2844
1.20
2.15
4.3
3.4
—
—
—
0
0
81
592
1.39
2.10
2.4
3.4
7.44
7.40
ph
—
9
76
242
2048
1.23
2.10
2.4
2.9
2.44
2.46
mmol/l
1.83
215
1805
37
229
1.63
2.10
2.0
1.9
4.54
5.01
mmol/24h
0.42
31
201
1102
10678
1.27
2.03
5.1
4.9
2.77
2.79
mmol/l
0.42
998
9815
243
2065
1.22
2.02
1.5
1.5
2.29
2.36
g/l
0.31
157
1245
1076
10400
1.25
2.00
4.5
4.4
1.53
1.53
mmol/l
0.10
976
9550
44
288
1.55
2.00
1.8
1.9
2.24
4.95
iu/l
3.58
12
107
160
1301
1.26
1.99
4.4
4.6
1.03
1.03
mmol/l
0.13
150
1194
179
1475
1.25
1.99
1.4
1.3
614.88
556.17
titre
0.16
43
324
78
579
1.37
1.87
1.2
1.2
—
—
—
0
0
89
678
1.34
1.82
1.2
1.2
166.65
161.94
u/ml
0.03
82
618
14
68
2.07
1.70
2.1
1.9
42.47
38.79
%
0.26
14
68
121
971
1.27
1.70
2.1
2.1
0.22
0.21
g/l
0.91
109
920
355
3168
1.17
1.70
2.0
2.1
146.77
218.28
u/l
1.28
329
2977
31
195
1.60
1.69
2.1
2.2
16.65
15.99
%
0.34
15
95
565
5224
1.15
1.67
4.4
3.8
0.00
0.00
estimate
0.75
160
1056
303
2674
1.18
1.66
2.5
2.5
321.94
5370.61
umol/l
8.35
261
2334
133
1084
1.25
1.65
1.4
1.5
—
—
—
0
0
23
135
1.72
1.63
1.6
1.2
—
—
nmol/l
—
0
0
44
303
1.47
1.62
1.7
2.0
10089.54
3561.30
u/l
0.45
17
119
42
287
1.48
1.61
1.0
1.1
—
—
—
0
0
24
144
1.68
1.58
1.7
1.2
—
—
—
0
0
76
980
0.76
1.53
2.1
2.2
58.15
35.36
u/l
0.54
66
826
62
464
1.35
1.46
1.2
1.2
—
—
—
0
0
565
5258
1.14
1.46
5.7
5.1
0.00
0.00
estimate
0.50
155
987
1036
10049
1.18
1.43
4.0
3.9
1.27
1.27
mmol/l
0.01
929
9157
570
5314
1.13
1.42
4.4
3.8
0.00
0.01
estimate
0.80
156
962
122
1005
1.24
1.40
2.8
2.0
352.56
374.90
nmol/l
0.59
106
920
295
2632
1.16
1.40
2.3
2.1
2.89
3.00
mg/l
0.38
246
2229
58
434
1.35
1.38
1.3
1.2
0.26
1.05
u/ml
—
9
32
1009
9774
1.17
1.38
5.8
5.6
39.97
39.65
mmol/mol
0.54
918
9030
5
120
0.41
1.37
1.8
1.6
—
—
—
0
0
6
23
2.62
1.37
1.2
1.1
—
—
—
0
0
5
17
2.95
1.36
1.6
1.4
—
—
—
0
0
19
112
1.71
1.36
5.2
2.1
31.95
32.11
pg
0.07
19
112
132
1102
1.22
1.35
4.3
3.9
13.64
19.10
ug/l
0.25
101
895
48
350
1.39
1.34
3.2
2.6
—
—
—
0
0
13
68
1.92
1.33
1.5
1.6
13.62
19.07
nmol/l
2.08
13
62
18
105
1.72
1.33
1.8
2.1
15.00
5.05
umol/l
—
10
69
12
61
1.98
1.33
1.7
1.4
1.56
1.59
g/l
0.09
12
61
332
3004
1.14
1.29
2.8
2.9
943.21
1136.41
ng/l
0.51
282
2529
5
18
2.78
1.28
8.4
2.7
—
—
—
0
0
217
1907
1.17
1.26
1.3
1.3
5.93
14.03
u/ml
1.91
97
724
152
1296
1.20
1.26
2.5
2.2
112.52
122.51
ug/g
0.23
117
1027
279
2502
1.15
1.24
1.5
1.5
21.71
21.36
nmol/l
0.13
240
2107
64
496
1.31
1.23
10.2
9.2
—
—
—
0
0
18
108
1.68
1.22
1.3
1.6
—
—
—
0
0
64
497
1.30
1.22
1.4
1.3
29.32
31.87
iu/l
0.26
59
426
6
26
2.31
1.18
1.5
2.5
9.72
9.79
mg/l
—
6
19
163
1409
1.18
1.17
1.5
1.5
—
—
—
0
0
167
1447
1.18
1.16
2.3
2.2
2.41
2.36
g/l
0.55
153
1334
5
20
2.51
1.15
1.6
1.9
—
—
—
0
0
0
36
0.00
1.14
0.0
2.2
—
—
—
0
0
20
127
1.58
1.12
1.3
1.4
286.15
329.70
pmol/l
0.33
20
115
385
3549
1.12
1.11
3.4
3.1
—
—
—
0
0
25
168
1.50
1.10
1.3
1.3
—
—
—
0
0
779
7468
1.11
1.09
3.7
3.7
—
—
—
0
0
30
210
1.44
1.09
2.9
2.5
7.65
8.01
kpa
0.64
30
205
243
2181
1.14
1.07
2.5
2.5
5.23
7.01
e6/l
0.99
215
1971
57
445
1.29
1.07
2.0
3.4
—
—
—
0
0
32
228
1.41
1.06
4.7
4.4
—
—
—
0
0
942
9134
1.13
1.06
16.7
16.4
15.12
14.94
%
0.40
931
8969
17
106
1.61
1.03
5.3
2.5
1.72
1.38
g/24h
0.19
12
55
54
422
1.29
1.01
2.3
2.1
12.29
12.40
nmol/l
0.03
46
377
21
139
1.52
1.00
2.5
2.6
—
—
—
0
0
10
176
0.56
1.00
1.9
1.4
—
—
—
0
0
25
172
1.46
1.00
3.1
2.4
—
—
—
0
0
96
805
1.21
0.99
4.0
2.6
65.40
72.55
e9/l
1.41
80
608
13
77
1.70
0.95
1.1
1.2
—
—
—
0
0
27
191
1.42
0.95
1.5
1.6
—
—
—
0
0
6
118
0.51
0.94
2.0
1.4
—
—
—
0
0
17
109
1.57
0.93
1.2
1.1
—
—
—
0
0
49
620
0.78
0.93
13.2
8.0
0.77
0.69
%
0.68
49
615
103
876
1.19
0.92
3.3
3.1
2.54
1.93
mmol/l
1.29
91
726
24
167
1.45
0.92
1.2
1.5
—
—
—
0
0
6
28
2.15
0.91
1.2
1.1
—
16.80
%
—
0
5
14
86
1.64
0.91
2.4
2.0
1.20
1.18
e9/l
0.03
14
80
34
253
1.35
0.91
2.1
2.6
1.21
1.50
mg/l
2.59
29
233
8
44
1.82
0.86
1.1
1.4
—
—
—
0
0
18
120
1.51
0.85
1.2
1.2
—
—
—
0
0
122
1062
1.16
0.85
3.6
3.1
0.79
0.77
ug/l
0.09
82
698
23
162
1.43
0.84
1.7
1.5
—
—
—
0
0
15
96
1.57
0.84
2.6
1.3
0.51
0.33
g/l
—
7
68
15
96
1.57
0.84
2.6
1.3
8.12
7.00
g/l
—
7
69
15
96
1.57
0.84
2.6
1.3
2.87
2.63
g/l
—
7
67
19
129
1.48
0.83
1.6
1.6
43.46
61.00
%
0.88
13
82
182
1634
1.13
0.82
1.6
1.7
—
—
—
0
0
87
739
1.19
0.81
2.4
2.4
16.75
27.71
au/ml
—
6
54
9
147
0.61
0.79
1.2
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
9
150
0.60
0.79
1.7
1.8
—
—
—
0
0
12
74
1.63
0.78
1.7
1.3
0.99
1.01
g/l
0.10
12
74
9
53
1.70
0.75
1.3
1.1
208.33
463.17
u/l
—
9
48
175
1578
1.13
0.75
2.3
2.2
13.88
13.01
umol/l
0.81
165
1460
214
1953
1.12
0.75
3.6
3.6
194.61
329.10
ng/l
0.63
147
1487
69
579
1.20
0.75
2.4
2.4
—
—
—
0
0
5
24
2.09
0.74
1.4
2.2
—
—
—
0
0
200
1821
1.12
0.73
5.7
5.0
2.13
2.60
ug/l
0.74
174
1619
14
207
0.67
0.73
2.6
2.9
32.71
35.55
umol/l
0.28
14
183
15
100
1.51
0.73
2.6
1.3
—
—
—
0
0
140
1248
1.14
0.72
1.3
1.4
—
—
—
0
0
17
117
1.46
0.72
1.4
1.1
—
—
—
0
0
227
2085
1.11
0.71
2.9
2.7
526.22
526.90
mosm/kgh2o
0.02
192
1801
60
501
1.21
0.69
1.0
1.1
—
122.36
—
0
11
52
627
0.82
0.69
12.7
7.8
1.36
1.39
%
0.11
52
621
35
276
1.28
0.67
1.1
1.2
—
1094.17
—
0
12
5
91
0.55
0.67
1.0
1.1
—
—
—
0
0
38
304
1.26
0.65
1.2
1.2
182.66
229.66
miu/ml
0.43
20
141
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
7
44
1.59
0.65
1.9
2.6
42371.43
37993.30
ug/l
—
7
44
35
278
1.27
0.64
1.3
1.2
—
—
—
0
0
39
314
1.25
0.64
2.1
1.6
322.82
309.52
mu/l
0.12
39
287
706
6833
1.08
0.64
3.1
3.0
47.21
46.11
u/l
0.11
660
6363
20
269
0.74
0.63
1.1
1.2
—
—
—
0
0
149
1347
1.12
0.63
2.3
2.3
24.02
22.40
%
0.62
120
1149
41
333
1.24
0.63
2.3
3.3
0.53
0.25
g/l
0.54
17
122
13
188
0.69
0.62
1.5
1.4
—
—
—
0
0
17
121
1.41
0.62
1.4
1.8
90.69
89.58
%
0.27
17
121
161
1464
1.11
0.62
2.1
1.9
—
—
—
0
0
23
173
1.34
0.62
1.2
1.3
—
—
—
0
0
34
423
0.80
0.61
2.2
1.8
1.53
1.50
g/l
0.04
29
366
21
156
1.35
0.61
2.4
1.6
0.83
0.82
g/l
0.01
13
118
13
187
0.69
0.61
1.5
1.4
—
—
—
0
0
861
8811
0.93
0.61
19.6
18.1
331.58
331.51
g/l
0.09
855
8749
386
3660
1.08
0.60
2.8
2.8
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
2.4
—
81.14
—
0
9
25
322
0.77
0.60
1.1
2.1
41.02
38.15
g/l
1.49
17
290
327
3083
1.08
0.59
3.1
3.1
41.55
75.03
e6/l
0.60
260
2351
16
219
0.73
0.58
1.4
1.3
—
—
—
0
0
9
60
1.50
0.54
2.9
1.8
—
—
—
0
0
14
99
1.42
0.54
1.9
1.5
—
—
—
0
0
36
437
0.82
0.54
3.8
2.9
24.65
24.06
mmol/l
0.67
36
422
9
61
1.48
0.53
1.1
1.2
—
—
—
0
0
14
193
0.72
0.53
1.5
1.5
—
—
—
0
0
20
152
1.32
0.52
1.2
1.3
107.92
113.85
u/ml
—
8
35
6
99
0.60
0.52
1.2
1.1
—
—
—
0
0
21
161
1.31
0.52
1.2
1.1
—
—
—
0
0
17
225
0.75
0.51
2.9
3.9
24.83
24.67
mg/l
—
7
139
9
65
1.39
0.50
1.2
1.3
88.00
75.94
umol/l
—
9
65
6
41
1.47
0.50
1.0
1.1
2077.83
1869.02
miu/ml
—
6
41
22
171
1.29
0.50
2.9
1.3
—
—
—
0
0
46
540
0.85
0.49
4.0
3.5
—
—
—
0
0
27
216
1.26
0.49
1.3
1.5
—
—
—
0
0
18
136
1.33
0.49
1.2
1.1
1.60
0.82
u/ml
0.28
11
61
7
46
1.52
0.48
3.4
1.7
—
—
—
0
0
79
887
0.88
0.48
1.4
1.4
—
—
—
0
0
7
48
1.46
0.47
1.0
1.0
—
—
—
0
0
13
94
1.39
0.46
1.0
1.2
—
—
—
0
0
13
94
1.39
0.46
1.2
1.3
—
—
—
0
0
14
103
1.36
0.45
2.4
2.6
—
—
—
0
0
9
127
0.71
0.43
1.8
1.2
—
—
—
0
0
12
87
1.38
0.42
1.1
1.2
—
—
—
0
0
253
2397
1.07
0.42
1.9
1.6
0.90
1.11
mg/l
0.77
195
1840
21
167
1.26
0.42
1.1
1.1
—
12.52
—
0
11
20
158
1.27
0.42
1.0
1.1
88.60
101.00
iu/ml
—
9
35
5
33
1.52
0.41
1.8
1.7
65.60
83.15
nmol/24h
—
5
33
295
2811
1.06
0.41
1.6
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
6.56
—
0
16
81
731
1.12
0.40
2.6
2.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
92
837
1.11
0.39
1.2
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
20
160
1.25
0.38
1.6
1.6
40.55
43.42
nmol/l
0.22
20
153
90
987
0.91
0.38
1.4
1.4
—
—
—
0
0
380
3657
1.06
0.38
3.5
3.6
76.70
88.82
e6/l
0.21
281
2545
15
192
0.78
0.38
1.2
1.3
85.88
59.90
mmol/l
—
8
158
9
68
1.33
0.37
1.0
1.1
—
9.65
—
0
18
119
1103
1.09
0.36
2.8
2.5
1.66
1.84
%
1.27
101
973
21
171
1.23
0.36
1.5
1.5
—
—
—
0
0
16
201
0.79
0.35
2.0
2.1
—
—
—
0
0
73
661
1.11
0.35
4.2
4.6
—
—
—
0
0
35
301
1.17
0.35
4.6
3.9
1.33
1.75
ratio
—
7
29
109
1177
0.92
0.35
2.0
2.5
9.11
7.42
umol/l
0.25
90
1016
93
854
1.10
0.34
2.5
2.8
68.70
66.89
g/l
1.67
84
776
163
1729
0.93
0.33
2.7
2.6
0.94
1.17
e6/l
0.59
97
949
52
463
1.13
0.33
1.8
1.9
—
—
—
0
0
6
89
0.67
0.33
1.3
1.3
—
—
—
0
0
38
434
0.87
0.33
1.6
1.6
—
—
—
0
0
82
751
1.10
0.33
1.2
1.2
—
—
—
0
0
15
120
1.25
0.30
1.2
1.0
1.20
3.04
u/ml
—
8
49
8
106
0.75
0.29
1.9
1.6
—
—
—
0
0
208
1988
1.06
0.28
1.8
1.7
1118.23
1202.79
nmol/l
0.71
158
1477
14
112
1.25
0.28
1.2
1.1
5.55
3.41
u/ml
—
7
36
19
158
1.21
0.28
1.1
1.2
—
—
—
0
0
12
94
1.28
0.28
1.2
1.4
1.36
1.35
nmol/l
0.01
12
82
56
616
0.90
0.28
11.9
8.1
93.18
93.91
%
0.31
56
609
35
308
1.14
0.28
4.7
3.9
38.19
68.49
mg/l
0.78
27
248
79
853
0.92
0.27
4.4
3.4
—
—
—
0
0
152
1600
0.94
0.26
2.8
2.7
2.33
3.19
e6/l
0.74
86
826
22
257
0.85
0.26
1.4
1.3
—
—
—
0
0
13
104
1.25
0.26
1.4
1.5
—
—
—
0
0
92
858
1.08
0.26
2.3
2.4
4.82
7.20
ug/l
0.84
70
748
87
810
1.08
0.26
3.7
2.9
114.80
194.98
ng/l
3.91
79
740
35
310
1.13
0.26
4.7
3.9
30.10
43.61
mg/l
0.65
27
251
20
169
1.19
0.26
1.3
1.2
299.67
256.39
u/ml
—
9
96
77
714
1.08
0.25
1.2
1.3
—
—
—
0
0
24
277
0.86
0.25
1.3
1.3
—
—
—
0
0
44
397
1.11
0.25
5.6
4.5
—
—
—
0
0
33
371
0.89
0.24
5.0
3.9
1.34
1.35
mmol/l
0.03
33
364
428
4180
1.04
0.23
3.9
3.5
5.76
5.85
ph
0.26
35
288
24
274
0.87
0.22
1.3
1.3
—
—
—
0
0
18
153
1.18
0.22
1.2
1.1
—
—
—
0
0
449
4392
1.03
0.22
2.0
2.0
101.78
96.19
pmol/l
1.38
228
2184
288
2796
1.04
0.21
2.8
2.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
51.82
—
0
11
0
11
0.00
0.21
0.0
3.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
43.50
—
0
6
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
3.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
350
3412
1.04
0.21
3.1
3.0
32.18
31.32
u/l
0.17
324
3257
18
154
1.17
0.21
1.2
1.1
—
—
—
0
0
5
43
1.16
0.21
1.6
3.3
—
—
—
0
0
76
712
1.07
0.21
3.8
3.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.02
—
0
13
0
13
0.00
0.21
0.0
1.0
—
1.81
—
0
7
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
125
1191
1.06
0.20
2.0
1.6
—
—
—
0
0
10
80
1.25
0.20
1.7
2.2
393.40
601.47
ml
—
5
53
88
830
1.06
0.20
1.5
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
1.94
—
0
7
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
48
1.25
0.20
1.0
1.3
—
—
—
0
0
9
111
0.81
0.20
1.6
2.7
—
—
—
0
0
9
111
0.81
0.20
4.3
6.5
14.21
12.21
mg/l
—
9
105
18
155
1.16
0.20
1.0
1.0
1.52
2.13
u/ml
—
8
64
6
50
1.20
0.19
1.2
3.3
—
—
—
0
0
6
50
1.20
0.19
1.0
1.2
—
—
—
0
0
118
1128
1.05
0.18
7.9
6.8
12.22
12.30
kpa
0.05
113
1084
118
1128
1.05
0.18
7.9
6.8
5.11
5.09
kpa
0.10
113
1083
16
184
0.87
0.17
1.3
1.2
—
—
—
0
0
5
66
0.76
0.17
1.4
1.5
5.58
7.72
ug/l
—
5
54
159
1536
1.04
0.16
1.9
1.9
29.02
29.50
s
0.60
151
1488
8
70
1.14
0.16
1.1
1.1
286.75
225.40
mg/l
—
8
61
8
72
1.11
0.16
1.0
1.5
10.29
11.71
umol/l
—
8
66
25
275
0.91
0.14
1.3
1.3
—
—
—
0
0
19
169
1.13
0.14
1.2
1.1
0.92
1.91
u/ml
0.52
11
87
15
131
1.15
0.14
4.3
2.2
—
—
—
0
0
86
899
0.95
0.14
1.6
1.4
—
—
—
0
0
32
295
1.09
0.14
1.3
1.2
36.22
2.29
u/ml
—
5
31
80
764
1.05
0.14
1.4
1.4
—
—
—
0
0
35
377
0.93
0.13
2.5
2.2
9.30
10.35
g/l
0.62
27
344
26
284
0.91
0.13
2.2
2.4
—
—
—
0
0
25
272
0.92
0.12
1.3
1.3
—
—
—
0
0
232
2271
1.03
0.12
4.8
4.3
1.02
1.02
kg/l
0.08
46
336
21
230
0.91
0.11
2.2
1.7
—
—
—
0
0
11
126
0.87
0.11
2.5
2.5
—
—
—
0
0
25
270
0.92
0.10
5.0
4.6
—
—
—
0
0
31
331
0.93
0.10
1.2
1.2
—
—
—
0
0
42
398
1.06
0.10
1.1
1.1
—
—
—
0
0
75
778
0.96
0.10
9.5
7.2
—
—
—
0
0
10
114
0.88
0.09
1.6
1.4
35.52
32.65
g/l
—
10
101
32
340
0.94
0.09
1.3
1.3
—
—
—
0
0
242
2461
0.98
0.09
4.1
3.8
—
—
—
0
0
44
420
1.05
0.08
1.1
1.1
—
—
—
0
0
5
61
0.82
0.08
1.8
2.1
1.54
2.92
ug/l
—
5
55
5
60
0.83
0.08
1.8
1.5
—
—
—
0
0
14
127
1.10
0.08
1.1
1.1
—
—
—
0
0
6
74
0.81
0.07
3.2
1.4
10.60
10.68
%
—
6
74
29
274
1.06
0.07
1.2
1.4
493.28
500.89
mg/l
0.06
29
261
35
333
1.05
0.07
1.5
1.4
267.00
294.19
ug/g
0.33
21
191
122
1195
1.02
0.07
1.6
1.7
—
—
—
0
0
8
94
0.85
0.06
1.0
1.1
—
—
—
0
0
23
244
0.94
0.06
1.4
1.6
448.43
920.94
e6/l
0.40
23
198
9
105
0.86
0.06
2.6
2.6
—
—
—
0
0
24
254
0.94
0.06
1.9
2.2
30.48
105.16
ug/min
1.74
12
149
10
90
1.11
0.05
1.6
1.4
19440.00
110494.37
e6/l
—
5
48
20
212
0.94
0.05
1.2
1.7
1.08
0.87
nmol/l
0.52
15
171
30
313
0.96
0.05
2.0
3.2
—
—
—
0
0
286
2838
1.01
0.04
3.0
2.9
0.43
0.47
e6/l
0.11
223
2146
114
1127
1.01
0.03
8.1
6.8
1.25
1.27
mmol/l
0.03
98
906
22
213
1.03
0.01
1.7
1.9
136.00
127.46
g/l
0.92
17
157
259
2600
1.00
0.01
3.3
3.6
94.34
92.55
%
0.56
254
2517
16
166
0.96
0.00
1.1
1.2
—
—
—
0
0
15
146
1.03
0.00
1.1
1.1
6.86
4.44
u/ml
—
7
69
11
108
1.02
0.00
1.3
1.1
—
—
—
0
0
14
139
1.01
0.00
2.5
3.0
—
—
—
0
0
15
151
0.99
0.00
1.0
1.1
—
—
—
0
0
59
588
1.00
0.00
1.6
1.4
—
—
—
0
0
25
249
1.00
0.00
1.4
1.6
15334.71
13137.73
e6/l
0.12
17
187
273
2729
1.00
0.00
6.1
6.6
—
—
—
0
0
12
117
1.03
0.00
1.3
3.8
—
—
—
0
0
6
59
1.02
0.00
1.3
3.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.0
—
—
—
0
0
9
97
0.93
-0.00
1.6
1.7
—
—
—
0
0
5
49
1.02
-0.00
2.2
2.1
44.92
185.70
ug/l
—
5
42
6
65
0.92
-0.00
1.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.1
1.0
—
—
—
0
0
15
150
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
11.6
—
—
—
0
0
7
70
1.00
-0.00
2.7
2.0
—
—
—
0
0
9
91
0.99
-0.00
1.4
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
14
140
1.00
-0.00
1.1
1.1
0.41
1.72
u/ml
—
7
57
11
110
1.00
-0.00
3.2
2.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
4.4
2.2
—
22.34
—
0
5
16
160
1.00
-0.00
1.2
1.2
10.14
4.81
u/ml
—
7
58
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.2
1.3
—
—
—
0
0
5
55
0.91
-0.00
7.6
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
97.40
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
343.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
2.50
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_THYROID and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_THYROID 0.943 [0.83, 1.06] 0.343
Birth year 0.993 [0.98, 1.0] 0.136

During the follow-up period (1.1.1998 — 31.12.2019), 416 out of 3924 females with CD2_BENIGN_THYROID died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_THYROID 1.195 [1.01, 1.42] 0.042
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 240 out of 1134 males with CD2_BENIGN_THYROID died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_THYROID.

N-year risk Females Males
1 0.091% 0.186%
5 0.58% 1.233%
10 1.361% 3.105%
15 2.586% 5.841%
20 4.419% 10.295%

Relationships between endpoints

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Index endpoint: CD2_BENIGN_THYROID – Benign neoplasm of thyroid gland

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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