This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Pectus excavatum
Q17_PECTUS_EXCAVATUM_WIDE
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
218 |
4. Check minimum number of eventsNone |
218 |
5. Include endpointsNone |
218 |
6. Filter based on genotype QC (FinnGen only) |
206 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF13
Similar endpoints
↥List of similar endpoints to
Pectus excavatum
based on the number of shared cases.
Similar with more cases:
- Congenital musculoskeletal deformities of head, face, spine and chest
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations, deformations and chromosomal abnormalities
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 206 | 77 | 129 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 18.52 | 21.59 | 16.69 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 218
- Matched controls
- 2180
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q67.6
ICD-10 Finland
Pectus excavatum
+∞
315.7
218
*
GAF03
NOMESCO Finland
Correction of pectus excavatum
+∞
68.4
62
*
GAF10
NOMESCO Finland
Removal of prosthetic material after correction of malformation of chest wall
+∞
67.2
61
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
14.3
33.1
32
26
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.4
21.9
50
113
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
18.2
99
419
75630
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Pectus excavatum
+∞
14.7
14
*
7548A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Other specified nonteratogenic anomalies[PECTUS EXCAVATUM]
+∞
14.7
14
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.5
12.4
50
170
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
12.2
72
308
Z31.5
ICD-10 Finland
Genetic counselling
4.7
12.0
30
72
5853
FHL
Anterior thoracoplasty (funnel breast, chicken breast)
+∞
11.6
11
*
XF404
NOMESCO Finland
Ambulatory ECG
5.0
10.3
23
50
R06.0
ICD-10 Finland
Dyspnoea
2.9
9.6
54
222
Q67.7
ICD-10 Finland
Pectus carinatum
38.4
9.1
11
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.2
8.5
24
63
L04
ICPC
Chest symptom/complaint
3.9
8.4
26
73
5859
FHL
Other operations in this group (eg removal of fixation plate)
+∞
8.4
8
*
GAF96
NOMESCO Finland
Other correction of malformation of chest wall
+∞
8.4
8
*
GAD00
NOMESCO Finland
Thoracoplasty without plombage
+∞
8.4
8
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
81
428
2.42
8.56
11.8
5.7
1.27
1.09
inr
0.99
24
149
30
100
3.32
7.54
5.1
12.3
2.14
0.61
mmol/l
1.07
25
75
197
1680
2.79
5.08
10.7
10.0
25.10
21.75
mg/l
0.63
142
1194
170
1386
2.03
4.52
7.1
7.9
103.82
102.10
ml/min/173m2
0.52
135
1057
35
166
2.32
4.50
4.0
3.2
589.19
1684.30
ng/l
0.60
28
127
105
781
1.66
3.37
4.0
5.4
5.92
6.33
mmol/l
1.93
93
693
15
55
2.85
3.22
4.9
10.5
95.94
95.16
%
0.21
15
55
15
56
2.80
3.13
4.9
10.3
0.63
0.75
%
0.74
15
56
15
56
2.80
3.13
4.9
10.3
0.88
1.49
%
2.61
15
56
176
1527
1.79
2.92
11.2
10.0
3.91
3.91
mmol/l
0.02
169
1468
176
1528
1.79
2.90
11.0
10.0
139.89
139.68
mmol/l
0.81
169
1474
71
499
1.63
2.74
5.1
5.6
38.70
38.08
g/l
0.36
63
471
211
1983
2.99
2.70
16.1
14.0
4.68
4.73
e12/l
0.94
204
1930
210
1979
2.67
2.45
16.3
14.2
41.70
44.07
%
0.49
203
1871
210
1976
2.71
2.44
16.1
14.0
249.27
255.17
e9/l
0.83
204
1924
53
359
1.63
2.34
2.8
2.5
20.61
15.47
ng/l
0.38
31
161
5
9
5.65
2.22
1.8
1.7
20.10
23.43
ug/l
—
5
9
191
1742
1.78
2.10
7.9
8.1
24.51
30.54
u/l
5.62
182
1682
45
301
1.62
2.08
1.6
2.7
1.32
1.13
mg/l
0.13
25
206
22
119
1.94
2.06
1.7
1.4
94.42
389.64
u/ml
0.87
22
112
24
134
1.89
2.05
4.7
7.4
104.67
104.72
mmol/l
0.03
24
134
46
312
1.60
2.01
2.2
2.4
—
—
—
0
0
7
21
3.41
1.98
1.1
1.2
168.33
229.72
pmol/l
—
7
21
77
594
1.46
1.85
5.8
8.5
1.20
1.22
mmol/l
1.15
66
517
5
13
3.91
1.72
1.0
1.1
—
—
—
0
0
0
48
0.00
1.72
0.0
1.1
—
—
—
0
0
20
113
1.85
1.67
3.9
4.4
—
—
—
0
0
7
153
0.44
1.50
1.3
2.5
29.14
31.46
u/l
—
7
130
69
542
1.40
1.46
5.7
8.1
1.21
1.22
mmol/l
1.28
62
508
18
105
1.78
1.38
2.7
2.9
—
—
—
0
0
9
44
2.09
1.28
1.0
1.2
—
—
—
0
0
20
124
1.67
1.26
5.8
6.2
3.77
1.09
mmol/l
1.38
13
88
123
1080
1.32
1.21
4.1
3.8
7.29
7.08
mm/h
0.07
117
1002
15
90
1.72
1.07
1.5
2.7
93.14
83.95
ml/min/173m2
—
7
40
24
164
1.52
1.04
2.6
7.8
2.86
1.41
mmol/l
1.14
24
120
20
131
1.58
1.04
3.1
2.7
262.45
3458.01
u/l
—
6
56
5
23
2.20
0.98
1.0
1.2
—
—
—
0
0
46
363
1.34
0.93
2.4
3.0
0.00
0.01
estimate
0.50
17
140
20
136
1.52
0.90
1.9
1.5
1162.87
1055.79
nmol/l
—
10
108
152
1405
1.27
0.86
3.9
4.0
1.71
1.83
mu/l
0.90
136
1309
6
108
0.54
0.74
1.3
1.5
—
—
—
0
0
74
641
1.23
0.73
2.6
2.6
—
—
—
0
0
80
701
1.22
0.70
2.5
2.9
0.00
0.00
estimate
-0.00
18
138
74
644
1.23
0.69
1.9
1.7
—
—
—
0
0
5
92
0.53
0.68
1.8
1.7
—
—
—
0
0
79
698
1.21
0.63
2.5
2.8
0.00
0.00
estimate
-0.00
19
144
16
113
1.45
0.63
6.0
8.2
1.08
1.39
mmol/l
1.08
16
108
128
1183
1.20
0.63
3.2
3.5
14.99
14.56
pmol/l
1.33
120
1078
46
384
1.25
0.63
1.4
1.6
96.24
96.72
pmol/l
0.02
24
205
8
49
1.66
0.63
3.2
4.3
56.80
48.12
%
—
8
49
136
1451
0.83
0.61
2.9
3.0
4.40
4.56
mmol/l
1.43
126
1385
106
966
1.19
0.60
8.5
9.0
3.60
3.96
e9/l
1.33
96
832
78
692
1.20
0.60
3.6
4.0
0.00
0.00
estimate
-0.00
18
147
0
22
0.00
0.59
0.0
2.3
—
0.00
—
0
22
0
22
0.00
0.59
0.0
2.3
—
0.00
—
0
22
22
167
1.35
0.59
2.6
7.7
6.41
5.84
kpa
1.64
22
162
13
89
1.49
0.59
4.8
5.2
10.29
9.60
kpa
0.83
13
84
61
529
1.21
0.59
2.0
2.4
—
—
—
0
0
0
23
0.00
0.58
0.0
2.3
—
0.00
—
0
23
8
54
1.50
0.58
3.5
6.4
1.31
1.76
%
—
8
54
6
36
1.69
0.57
1.0
1.1
—
—
—
0
0
15
201
0.73
0.52
1.5
1.6
—
—
—
0
0
47
403
1.21
0.51
1.8
2.7
55.29
56.57
u/l
0.11
38
375
136
1440
0.85
0.51
2.9
2.9
1.38
1.37
mmol/l
0.05
125
1370
39
328
1.23
0.51
2.5
2.5
2.66
2.76
mg/l
0.13
32
283
12
84
1.45
0.50
1.1
1.2
3.43
2.54
u/ml
—
5
58
7
106
0.65
0.50
2.0
1.7
—
—
—
0
0
35
292
1.24
0.49
1.6
2.2
—
—
—
0
0
138
1456
0.86
0.48
2.9
3.1
2.66
2.81
mmol/l
1.45
126
1380
78
709
1.16
0.43
2.8
2.9
74.05
77.36
ug/l
0.11
69
667
6
93
0.64
0.43
1.2
1.5
—
—
—
0
0
6
93
0.64
0.43
1.2
1.5
—
—
—
0
0
6
93
0.64
0.43
1.2
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
60
537
1.16
0.41
2.6
2.7
—
—
—
0
0
0
17
0.00
0.41
0.0
1.9
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
64
576
1.16
0.41
2.5
2.9
73.10
68.64
nmol/l
0.79
59
535
5
34
1.48
0.40
1.0
1.1
—
—
—
0
0
17
214
0.78
0.40
1.8
2.9
4.86
2.42
e6/l
—
5
119
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
5
36
1.40
0.38
10.2
5.0
59.00
52.06
%
—
5
36
18
223
0.79
0.38
1.9
2.9
1.46
0.55
e6/l
—
7
127
5
76
0.65
0.36
3.8
5.2
93.40
91.76
%
—
5
76
25
209
1.22
0.36
7.0
2.9
78.31
955.32
ng/l
0.84
15
116
6
43
1.41
0.35
1.2
1.6
310.67
363.95
mg/l
—
6
43
26
221
1.20
0.32
1.1
1.2
13.12
23.32
iu/ml
—
6
70
10
131
0.75
0.32
1.8
1.4
—
—
—
0
0
7
98
0.70
0.31
1.4
1.4
—
—
—
0
0
28
242
1.18
0.30
1.5
2.1
—
—
—
0
0
16
131
1.24
0.28
1.9
1.6
—
—
—
0
0
16
131
1.24
0.28
1.8
1.6
—
—
—
0
0
22
187
1.20
0.28
1.9
1.9
—
—
—
0
0
18
214
0.83
0.27
1.4
1.4
—
—
—
0
0
112
1068
1.10
0.26
6.9
6.8
87.60
85.14
u/l
0.16
106
1002
18
211
0.84
0.24
1.1
1.2
1.32
7.25
u/ml
—
9
82
62
577
1.10
0.23
2.1
2.5
—
—
—
0
0
5
38
1.32
0.23
2.2
1.7
—
—
—
0
0
11
88
1.26
0.23
1.4
1.6
—
—
—
0
0
8
103
0.77
0.21
5.5
6.7
76.96
62.13
ng/l
—
8
95
0
11
0.00
0.21
0.0
1.3
—
2.55
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.30
—
0
11
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
11.17
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
1493.50
—
0
12
0
12
0.00
0.21
0.0
1.0
—
105.92
—
0
12
123
1186
1.09
0.21
3.4
3.8
35.51
37.12
mmol/mol
2.07
117
1128
5
43
1.17
0.21
1.4
2.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
51
1.18
0.19
1.3
1.7
—
—
—
0
0
58
544
1.09
0.19
1.5
1.4
6.29
1.29
u/ml
0.39
14
123
8
69
1.17
0.16
2.8
1.7
—
—
—
0
0
8
71
1.13
0.16
1.3
1.3
—
—
—
0
0
17
149
1.15
0.16
1.1
1.0
—
—
—
0
0
114
1175
0.94
0.15
2.3
3.4
28.21
35.37
u/l
1.32
105
1131
135
1383
0.94
0.15
2.5
2.8
1.09
1.25
mmol/l
2.13
122
1312
23
252
0.90
0.13
3.5
4.3
6.16
21.77
mg/mmol
1.19
14
185
5
47
1.07
0.09
1.4
2.3
—
—
—
0
0
5
48
1.04
0.09
1.4
2.8
—
—
—
0
0
6
56
1.07
0.08
1.0
1.2
—
—
—
0
0
6
58
1.04
0.08
1.0
1.2
—
—
—
0
0
5
64
0.78
0.08
2.0
1.7
—
0.33
—
0
11
11
123
0.89
0.08
1.4
2.0
—
—
—
0
0
7
85
0.82
0.07
1.3
1.6
—
—
—
0
0
41
395
1.05
0.06
2.6
2.8
2.36
2.37
mmol/l
0.20
36
360
47
459
1.03
0.03
2.4
3.4
—
—
—
0
0
19
197
0.96
0.01
1.4
1.4
—
—
—
0
0
132
1328
0.98
0.01
3.0
2.9
5.42
5.58
mmol/l
1.53
119
1234
36
367
0.98
0.01
1.9
3.2
0.07
0.23
e6/l
1.41
25
280
14
141
0.99
0.00
1.6
2.5
24.59
25.71
%
—
9
133
169
1689
1.00
0.00
3.7
3.7
—
—
—
0
0
15
155
0.97
0.00
1.3
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
3.5
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
7.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
6.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
9.16
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
102.67
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
28.22
—
0
6
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
7
69
1.01
-0.00
1.6
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
9.0
—
—
—
0
0
8
89
0.90
-0.00
1.4
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
28.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
284.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_PECTUS_EXCAVATUM_WIDE – Pectus excavatum
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).