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Prophylactic surgery

Z21_PROPHYLACT_SURGE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Z40
  • Cause of death: ICD-10 Z40

2 out of 7 registries used, show all original rules.

292

4. Check minimum number of events

None

292

5. Include endpoints

None

292

6. Filter based on genotype QC (FinnGen only)

271

Control definitions (FinnGen only)

Control exclude
Z21_PERSONS_ENCOUNTERI_HEALTH_SERVI_SPECIFIC_PROCED_HEALTH_CARE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z4|Z5[0-4]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 271 254 17
Unadjusted period prevalence (%) 0.08 0.09 0.01
Median age at first event (years) 45.65 45.44 48.84

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
292
Matched controls
2920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z40.0
ICD-10 Finland
Prophylactic surgery for risk-factors related to malignant neoplasms
14930.2
319.1
246
*
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
116.7
307.7
184
42
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
101.7
206.0
109
17
Z31.5
ICD-10 Finland
Genetic counselling
29.6
196.4
171
133
HAE99
NOMESCO Finland
Other reconstruction of breast
99.6
170.8
90
13
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
98.0
168.5
89
13
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
50.9
155.1
94
27
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
24.5
151.4
128
90
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
18.4
135.8
140
139
TQW20
NOMESCO Finland
Tatoe
69.2
124.0
69
13
HA1AA
NOMESCO Finland
X-ray mammography
16.5
123.3
134
143
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
49.9
115.4
69
18
HAC20
NOMESCO Finland
Total mastectomy
25.0
111.4
86
48
R4110
NOMESCO Finland
Physiotherapy
12.5
105.5
202
443
115
Kela drug reimbursment
Breast cancer
12.7
98.3
125
163
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
+∞
93.9
85
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
21.4
88.7
72
44
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
13.7
84.2
92
95
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
48.9
82.4
49
12
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
28.1
80.5
57
25
H02AB02
ATC
dexamethasone; systemic
10.4
77.6
110
161
PJA12
NOMESCO Finland
Sentinel node biopsy
10.2
74.6
106
155
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
31.5
74.1
50
19
L02BA01
ATC
tamoxifen; oral
13.4
68.8
73
71
WX402
NOMESCO Finland
General anaesthesia
7.7
68.6
156
379
WX404
NOMESCO Finland
Intravenous generell anesthesy
7.4
66.6
163
424
ZXE40
NOMESCO Finland
More than seven and less than nine hours
32.5
63.2
42
15
B01AB05
ATC
enoxaparin; parenteral
6.9
60.8
174
516
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
10.7
59.3
74
90
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
26.3
57.3
41
18
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
13.0
50.1
52
48
HAC10
NOMESCO Finland
Subcutaneous mastectomy with preservation of mamilla
107.5
49.7
53
6
ZXE30
NOMESCO Finland
More than five and less than seven hours
13.8
49.4
49
42
ZXA00
NOMESCO Finland
Right side
5.7
48.0
135
380
TQB05
NOMESCO Finland
Puncture of skin of trunk
71.5
47.2
53
9
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
11.6
47.1
53
55
A03FA01
ATC
metoclopramide; systemic, rectal
5.6
46.6
140
415
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
117.3
46.4
49
5
ZXD10
NOMESCO Finland
Scheduled procedure
5.6
45.6
197
785
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
97.9
45.5
49
6
ZXA05
NOMESCO Finland
Left side
5.6
45.0
124
340
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
498.2
44.5
43
*
WX408
NOMESCO Finland
General anesthesy, balanced
5.3
43.7
140
434
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
10.1
43.5
54
64
C50.99
ICD-10 Finland
Breast, unspecified
12.8
42.6
44
40
ZXE10
NOMESCO Finland
More than one and less than three hours
5.1
42.3
180
697
HA1CM
NOMESCO Finland
Mammary gland extensive MRI examination with 3 Tesla magnet
158.3
39.8
41
*
A04AA01
ATC
ondansetron; systemic, rectal
7.3
35.6
59
98
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
45.5
35.5
43
11
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
10.4
34.7
41
45
A04AD12
ATC
aprepitant; systemic
14.9
34.5
32
24
A04AA02
ATC
granisetron; systemic, transdermal
8.4
33.7
48
67
ZZF00
NOMESCO Finland
Graft of adipose tissue
43.1
33.5
41
11
HAD20
NOMESCO Finland
Liposuction of breast
361.4
32.5
32
*
R4120
NOMESCO Finland
Occupational therapy
7.4
32.4
52
83
TPH07
NOMESCO Finland
Cathetrisation of artery
7.0
32.2
55
94
Z2221
NOMESCO Finland
Medical doctor
4.1
32.2
155
626
ZZR10
NOMESCO Finland
Flap of skin and muscle
60.2
32.1
37
7
Z3226
NOMESCO Finland
Physiotherapist
4.6
30.1
93
270
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
5.3
30.0
73
174
Z3231
NOMESCO Finland
Registered nurse
4.1
30.0
124
446
JN4BD
NOMESCO Finland
Extensive body CT
6.3
29.6
56
106
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
8.1
29.2
42
59
ZXE20
NOMESCO Finland
More than three and less than five hours
5.1
28.9
72
175
Z40.8
ICD-10 Finland
Other prophylactic surgery
+∞
28.6
27
*
ZXA10
NOMESCO Finland
Bilateral
4.4
28.3
91
271
Z80.4
ICD-10 Finland
Family history of malignant neoplasm of genital organs
52.9
28.1
33
7
TQW99
NOMESCO Finland
Other minor procedure on skin
8.6
26.5
36
47
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
80.0
26.3
29
*
A04AA55
ATC
palonosetron, combinations; systemic
7.2
26.0
42
67
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
9.2
25.8
33
40
ZX120
NOMESCO Finland
Intravenous
5.8
25.3
51
102
C50
ICD-10 Finland
Malignant neoplasm of breast
8.3
25.2
35
47
L01BC06
ATC
capecitabine; oral
10.0
24.3
29
32
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
29.7
24.1
32
12
L03AA13
ATC
pegfilgrastim; parenteral
6.5
22.1
39
68
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.6
21.3
92
330
ZXE00
NOMESCO Finland
One hour or less
3.2
21.3
167
859
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
6.7
20.8
35
58
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
52.0
20.5
24
5
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
43.4
19.8
24
6
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
6.6
19.5
33
55
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.2
19.2
35
63
Z40.9
ICD-10 Finland
Prophylactic surgery, unspecified
+∞
19.0
18
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
6.2
18.7
34
61
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
5.6
18.7
38
76
1CD02, ,
NOMESCO Finland
19.2
18.6
28
16
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.9
18.2
168
920
L02BG04
ATC
letrozole; oral
4.3
17.7
52
141
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
5.4
17.4
37
77
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
37.5
16.9
21
6
HAD55
NOMESCO Finland
Incision of periprosthetic capsule of breast
+∞
16.8
16
*
L02AE03
ATC
goserelin; implant
19.4
16.8
25
14
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
29.6
16.8
22
8
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
95.6
16.8
18
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
42.8
16.5
20
5
QBJ00
NOMESCO Finland
Liposuction in trunk
42.8
16.5
20
5
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
5.1
16.4
37
81
B01AB04
ATC
dalteparin; parenteral
5.6
15.9
32
63
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
90.0
15.7
17
*
ZXM40
NOMESCO Finland
Use of fluorescent substance
168.7
15.6
16
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.8
15.0
113
544
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
4.2
15.0
44
119
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
12.9
14.9
26
22
HAB40
NOMESCO Finland
Wedge excision of mammary gland
4.7
14.8
37
88
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
15.3
14.8
24
17
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
10.9
14.3
27
27
L02BG06
ATC
exemestane; oral
10.9
14.3
27
27
WX110
NOMESCO Finland
Infiltration anesthesia
3.4
13.9
248
1812
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
5.8
13.8
26
48
ZXD20
NOMESCO Finland
Day surgery
3.3
13.7
61
218
HWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of mammary gland
25.7
12.6
17
7
HAD57
NOMESCO Finland
Resection of periprosthetic capsule of breast
135.6
12.5
13
*
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
13.2
12.3
21
17
HWH99
NOMESCO Finland
Other reoperation in surgery of mammary gland
39.4
12.3
15
*
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
4.7
12.0
29
67
N64.9
ICD-10 Finland
Disorder of breast, unspecified
11.8
11.7
21
19
ZZS50
NOMESCO Finland
Insertion of tissue expander
+∞
11.5
11
*
HA1TE
NOMESCO Finland
Supplementary or limited ultrasound examination of mammary glands
15.9
11.5
18
12
R2110
NOMESCO Finland
Giving the first information
3.4
11.3
44
144
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
10.7
11.2
21
21
HWD00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of mammary gland
18.7
10.8
16
9
HAD99
NOMESCO Finland
Other plastic operation on breast
22.5
10.8
15
7
I97.2
ICD-10 Finland
Postmastectomy lymphoedema syndrome
22.5
10.8
15
7
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
15.0
10.6
17
12
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
11.2
10.4
19
18
N02BE01
ATC
paracetamol; systemic, rectal
5.1
10.4
277
2290
N63
ICD-10 Finland
Unspecified lump in breast
3.2
10.3
44
152
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
11.9
10.2
18
16
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
15.3
10.1
16
11
FM1FN
NOMESCO Finland
Heart function isotope examination
41.6
10.0
12
*
Z31.6
ICD-10 Finland
General counselling and advice on procreation
12.8
10.0
17
14
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
9.9
119
684
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
20.9
9.9
14
7
L02AE02
ATC
leuprorelin; implant, parenteral
5.6
9.8
19
36
Z50.1
ICD-10 Finland
Other physical therapy
56.9
9.7
11
*
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.4
9.5
19
37
X21
ICPC
Breast sympt/compl female other
5.4
9.5
19
37
Y83.4
ICD-10 Finland
Other reconstructive surgery as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
+∞
9.4
9
*
ZZS55
NOMESCO Finland
Distension of tissue expander
+∞
9.4
9
*
LCA06
NOMESCO Finland
Biopsy of endometrium
2.5
9.3
69
320
TQW40
NOMESCO Finland
Remowal of suture of skin
3.7
9.2
30
87
ZX112
NOMESCO Finland
Subcutaneous
12.0
9.2
16
14
ZY010
NOMESCO Finland
Hospital outpatient
4.0
9.1
27
73
X76
ICPC
Malignant neoplasm breast female
7.9
9.1
20
27
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
7.9
9.1
20
27
Z51.5
ICD-10 Finland
Palliative care
38.0
9.1
11
*
L03AA02
ATC
filgrastim; parenteral
8.4
9.0
19
24
Z80.8
ICD-10 Finland
Family history of malignant neoplasm of other organs or systems
24.9
9.0
12
5
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
7.6
8.9
20
28
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
8.7
29
85
A02BC02
ATC
pantoprazole; systemic
2.2
8.6
205
1513
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
20.8
8.5
12
6
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.5
8.5
30
92
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
9.0
8.4
17
20
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
11.2
8.4
15
14
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
15.0
8.3
13
9
J01DB01
ATC
cefalexin; oral
2.9
8.2
259
2131
1XC03, ,
NOMESCO Finland
34.4
8.1
10
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
10.5
8.1
15
15
S18
ICPC
Laceration/cut
2.0
8.1
129
814
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
22.8
8.1
11
5
N02AA05
ATC
oxycodone; systemic
2.9
8.0
40
151
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.4
8.0
65
313
TQW11
NOMESCO Finland
Vacuum treatment of wound
8.8
7.9
16
19
ZXD05
NOMESCO Finland
Urgent procedure
2.1
7.9
109
651
N02AX02
ATC
tramadol; systemic, rectal
2.0
7.9
123
769
ZX090
NOMESCO Finland
Other technic of radiotherapy
6.2
7.8
20
34
ACC19
NOMESCO Finland
Transcision of peripheral nerve: other or unspecified
15.6
7.8
12
8
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
3.8
7.8
24
67
SPAT1324
SPAT
Screening procedure
0.3
7.7
23
645
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.4
7.6
29
93
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
25.8
7.6
10
*
WX702
NOMESCO Finland
Supraglottic ventilation device
3.6
7.4
25
74
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
8.7
7.4
15
18
Z80.9
ICD-10 Finland
Family history of malignant neoplasm, unspecified
+∞
7.3
7
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
7.6
7.3
16
22
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
16.3
7.3
11
7
N06AX16
ATC
venlafaxine; oral
2.3
6.8
57
278
TQD05
NOMESCO Finland
Puncture of skin of lower limb
23.1
6.7
9
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
4.1
6.5
18
46
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
6.5
32
120
QWF00
NOMESCO Finland
Reoperation for insufficiency of suture in plastic surgery of skin
71.3
6.5
7
*
HAD00
NOMESCO Finland
Augmentation mammoplasty
71.3
6.5
7
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
4.0
6.4
18
47
M05BX04
ATC
denosumab; parenteral
5.3
6.3
18
36
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
6.3
6
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
8.9
6.1
12
14
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.0
59
306

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
111
160
10.58
79.44
3.0
3.8
5.14
7.12
ug/l
0.24
68
126
133
325
6.68
56.54
1.8
1.2
—
—
—
0
0
195
716
6.19
51.50
2.6
1.8
—
—
—
0
0
161
537
5.45
46.55
2.1
1.8
—
—
—
0
0
38
30
14.41
39.94
1.1
1.1
—
—
—
0
0
63
105
7.38
38.02
6.8
5.6
—
—
—
0
0
58
92
7.62
36.56
1.4
1.3
—
—
—
0
0
81
180
5.84
36.52
1.5
1.3
—
—
—
0
0
52
77
8.00
34.76
7.5
5.2
24.30
24.51
mmol/l
0.18
52
77
52
88
6.97
30.67
7.5
6.4
96.24
94.27
%
2.08
52
88
52
89
6.89
30.33
7.5
6.3
0.94
0.67
%
3.23
52
89
51
88
6.81
29.48
7.7
6.4
1.33
1.34
%
0.03
51
88
207
1072
4.20
28.94
3.0
2.0
—
—
—
0
0
65
146
5.44
28.52
6.8
5.5
-0.21
0.75
mmol/l
1.63
60
120
209
1112
4.09
27.55
3.0
2.2
—
—
—
0
0
35
49
7.98
24.30
2.4
2.7
10.71
2732.74
u/ml
0.49
30
43
130
574
3.28
21.60
9.8
6.1
—
—
—
0
0
78
250
3.89
21.37
2.1
1.8
—
—
—
0
0
62
169
4.39
21.19
5.3
5.4
105.50
104.65
mmol/l
0.89
62
169
140
675
3.06
19.55
7.6
2.6
2.38
2.36
mmol/l
1.61
132
614
161
841
3.04
19.43
5.6
4.1
1.19
1.22
mmol/l
6.55
149
776
168
938
2.86
17.28
6.3
4.6
1.19
1.23
mmol/l
6.64
151
815
225
1496
3.20
16.26
3.3
2.9
—
—
—
0
0
87
370
2.92
14.55
3.3
3.5
—
—
—
0
0
199
1311
2.63
13.29
11.4
7.9
3.54
3.85
e9/l
1.34
171
1150
26
28
10.08
13.28
1.1
1.1
—
—
—
0
0
108
565
2.45
11.55
3.3
3.0
7.38
7.40
ph
—
9
94
57
218
3.01
11.31
2.1
1.4
—
—
—
0
0
65
268
2.83
11.26
2.7
2.3
4.04
4.15
e6/l
0.03
34
137
99
507
2.44
11.01
2.8
2.4
0.12
0.30
e6/l
1.45
66
365
103
555
2.32
10.07
2.8
2.5
49.18
82.50
e6/l
0.34
71
403
273
2250
4.28
9.95
22.7
12.1
330.37
331.90
g/l
2.31
273
2236
171
1142
2.20
9.76
5.2
3.3
6.50
6.34
mmol/l
0.62
164
1028
126
754
2.18
9.42
1.4
1.6
—
—
—
0
0
120
711
2.17
9.14
3.4
2.9
47.75
67.01
e6/l
0.36
75
447
95
517
2.24
8.90
2.8
2.5
—
—
—
0
0
286
2602
5.82
7.43
17.2
9.8
66.13
66.92
umol/l
0.33
286
2602
43
189
2.50
6.41
2.6
2.2
32.06
32.63
u/l
0.03
36
164
22
66
3.52
6.41
4.0
7.8
—
—
—
0
0
17
45
3.95
5.90
1.1
1.1
7.57
3.33
u/ml
—
7
15
86
535
1.86
5.20
1.5
1.6
1.47
0.85
mg/l
0.42
64
407
277
2484
3.24
5.18
14.8
8.8
25.46
18.31
mg/l
3.08
245
1849
19
63
3.16
4.76
1.2
2.0
—
—
—
0
0
61
362
1.87
4.20
2.2
2.3
551.54
535.40
mosm/kgh2o
0.18
52
309
54
308
1.92
4.19
2.8
2.8
69.16
470.33
ng/l
0.87
31
178
14
42
3.45
4.10
1.2
1.3
—
—
—
0
0
7
7
10.21
4.03
1.1
1.1
—
—
—
0
0
63
387
1.80
3.87
2.1
2.1
10.02
7.99
e6/l
0.32
53
339
19
72
2.75
3.81
1.1
1.1
—
—
—
0
0
37
199
1.98
3.40
1.3
1.4
—
—
—
0
0
36
621
0.52
3.39
2.7
3.2
0.00
0.00
estimate
—
8
218
34
182
1.98
3.17
3.2
3.4
1.04
0.98
mmol/l
0.75
34
168
8
16
5.11
3.07
1.1
1.1
—
—
—
0
0
100
746
1.52
2.78
10.4
7.8
1.14
1.10
inr
0.15
23
226
181
1532
1.48
2.64
4.0
3.6
—
903.94
—
0
17
49
312
1.69
2.64
1.2
1.5
—
—
—
0
0
126
1001
1.46
2.52
4.7
5.5
0.67
0.70
%
0.37
118
935
9
26
3.54
2.50
2.6
1.8
3.12
7.63
u/ml
—
9
26
144
1175
1.44
2.49
5.5
5.5
1.83
1.92
e9/l
0.84
126
1067
23
118
2.03
2.43
1.8
2.1
—
—
—
0
0
139
1132
1.43
2.40
5.5
5.5
0.03
0.04
e9/l
0.89
115
1006
124
992
1.43
2.35
6.5
7.1
0.00
0.00
e9/l
0.96
85
818
97
743
1.46
2.31
1.9
1.8
104.40
101.21
pmol/l
0.42
50
376
135
1100
1.42
2.30
4.6
5.4
29.53
29.86
%
0.15
127
1040
138
1130
1.42
2.28
5.5
5.5
0.53
0.52
e9/l
0.10
115
1006
134
1092
1.42
2.27
4.7
5.2
56.33
56.19
%
0.05
126
1030
130
1055
1.42
2.25
4.7
5.3
2.48
2.76
%
0.90
120
991
5
9
5.63
2.22
6.8
6.3
9.64
11.00
mg/l
—
5
9
8
24
3.40
2.19
1.0
2.0
—
—
—
0
0
130
1059
1.41
2.19
4.8
5.6
8.05
7.95
%
0.13
122
998
8
191
0.40
2.14
1.9
3.0
—
—
—
0
0
6
15
4.06
2.05
1.3
1.1
—
—
—
0
0
11
44
2.56
2.03
3.2
2.3
—
—
—
0
0
48
329
1.55
1.93
3.3
2.0
2.46
2.43
mmol/l
1.08
42
296
23
132
1.81
1.80
1.3
1.4
—
—
—
0
0
23
132
1.81
1.80
1.3
1.4
—
—
—
0
0
278
2654
1.99
1.77
12.0
8.6
—
—
—
0
0
69
520
1.43
1.75
2.7
3.0
—
—
—
0
0
81
629
1.40
1.74
2.6
2.1
—
—
—
0
0
5
13
3.89
1.72
1.0
1.8
8.24
9.67
umol/l
—
5
13
140
1188
1.34
1.71
5.7
5.9
0.17
0.17
e9/l
0.22
120
1064
36
522
0.65
1.67
2.9
2.8
—
—
—
0
0
6
19
3.20
1.67
1.2
1.3
—
—
—
0
0
23
136
1.75
1.64
1.3
1.5
—
—
—
0
0
193
1735
1.33
1.51
3.2
2.6
35.71
34.91
u/l
0.10
186
1651
33
222
1.55
1.46
1.3
1.2
—
—
—
0
0
14
75
1.91
1.37
3.2
2.5
—
—
—
0
0
31
215
1.49
1.22
1.4
1.4
—
—
—
0
0
65
520
1.32
1.14
2.0
2.1
7100.49
5367.90
umol/l
0.09
57
475
37
271
1.42
1.12
1.3
1.3
—
—
—
0
0
5
21
2.40
1.09
1.0
1.1
—
—
—
0
0
9
46
1.99
1.04
2.8
1.8
—
—
—
0
0
5
23
2.19
0.98
1.4
1.4
—
—
—
0
0
91
1051
0.81
0.94
2.1
2.3
—
—
—
0
0
67
553
1.27
0.94
1.4
1.7
—
—
—
0
0
10
55
1.85
0.93
1.2
1.2
—
108.57
—
0
7
55
668
0.78
0.88
2.0
2.7
—
—
—
0
0
12
72
1.70
0.86
2.0
1.7
—
—
—
0
0
59
709
0.79
0.86
2.6
2.6
63.90
18.05
ng/l
0.55
25
349
10
57
1.78
0.84
1.1
1.1
—
—
—
0
0
10
57
1.78
0.84
1.1
1.1
—
—
—
0
0
5
26
1.94
0.71
1.0
1.4
—
—
—
0
0
223
2329
0.82
0.71
3.2
3.4
1.26
1.22
mmol/l
0.41
215
2204
7
41
1.72
0.70
1.4
1.1
—
—
—
0
0
5
27
1.87
0.68
1.0
1.1
—
—
—
0
0
5
27
1.87
0.68
1.0
1.3
—
—
—
0
0
215
2044
1.20
0.66
4.2
4.2
13.95
14.35
pmol/l
1.79
208
1924
23
173
1.36
0.64
2.6
2.7
4.30
4.53
e9/l
0.18
23
157
6
105
0.56
0.63
1.3
1.1
—
—
—
0
0
43
514
0.81
0.61
2.6
3.1
1.02
1.02
kg/l
—
6
71
31
247
1.29
0.60
1.2
1.3
—
—
—
0
0
10
64
1.58
0.59
1.0
1.3
251.00
315.10
ug/g
—
5
31
246
2376
1.22
0.59
5.0
4.8
1.75
2.25
mu/l
0.51
237
2246
5
88
0.56
0.57
1.2
1.6
1.33
1.21
g/l
—
5
83
12
82
1.48
0.55
1.8
2.1
—
—
—
0
0
118
1088
1.14
0.50
4.7
5.6
—
—
—
0
0
69
612
1.17
0.49
1.2
1.3
0.73
1.92
u/ml
—
9
181
7
47
1.50
0.48
1.9
1.8
263.57
162.10
ug/l
—
7
42
14
187
0.74
0.47
4.8
3.3
—
—
—
0
0
61
540
1.16
0.45
1.4
1.3
1.73
2.16
g/l
1.82
31
348
7
51
1.38
0.44
1.0
2.1
1.99
1.19
g/l
—
7
45
5
33
1.52
0.41
1.2
1.3
—
—
—
0
0
16
123
1.32
0.41
1.1
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
33.31
—
0
16
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
38
439
0.85
0.40
1.4
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.9
—
—
—
0
0
11
80
1.39
0.39
1.4
1.3
—
—
—
0
0
5
36
1.40
0.38
4.0
3.0
—
—
—
0
0
13
169
0.76
0.38
1.5
1.2
—
49.00
—
0
8
237
2428
0.87
0.36
3.5
3.7
1.63
1.56
mmol/l
2.06
230
2307
9
124
0.72
0.36
6.0
4.5
3.04
2.03
ug/l
—
9
112
6
46
1.31
0.33
1.2
1.3
—
—
—
0
0
243
2478
0.88
0.29
4.2
4.1
2.99
2.93
mmol/l
0.61
237
2348
8
110
0.72
0.29
2.1
2.3
64.52
69.33
g/l
—
8
103
14
173
0.80
0.29
1.1
1.2
—
—
—
0
0
8
64
1.26
0.27
1.3
2.3
0.84
0.64
%
—
8
64
52
569
0.90
0.27
3.3
2.9
6.58
7.63
mmol/l
0.72
44
502
8
66
1.22
0.27
1.3
2.3
1.70
0.97
%
—
8
66
167
1611
1.09
0.26
3.9
3.6
—
—
—
0
0
33
369
0.88
0.24
1.2
1.4
331.43
555.56
titre
—
7
81
71
665
1.09
0.22
1.7
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
0.27
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
2246.90
—
0
10
0
10
0.00
0.21
0.0
2.3
—
2183.00
—
0
10
15
126
1.20
0.21
1.1
1.3
150.56
272.14
miu/ml
—
9
64
0
12
0.00
0.21
0.0
1.1
—
198.39
—
0
12
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
11
90
1.23
0.19
2.5
1.6
—
—
—
0
0
14
164
0.85
0.19
2.6
2.7
—
—
—
0
0
15
173
0.86
0.17
1.6
2.2
144.88
2196.55
u/l
—
8
69
8
70
1.15
0.16
3.5
3.9
—
—
—
0
0
26
236
1.11
0.15
1.3
1.4
—
—
—
0
0
99
953
1.06
0.15
2.5
2.8
6.15
5.87
ph
0.58
13
92
7
86
0.81
0.15
24.7
5.7
—
—
—
0
0
15
132
1.14
0.13
2.7
2.3
—
—
—
0
0
218
2149
1.06
0.13
4.4
4.4
38.48
38.14
mmol/mol
0.24
210
2035
36
385
0.93
0.13
1.4
1.4
—
—
—
0
0
11
127
0.86
0.12
1.8
1.7
1.41
1.33
g/l
0.13
11
121
13
147
0.88
0.11
1.0
1.0
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
6
54
1.11
0.09
1.2
1.3
—
—
—
0
0
49
511
0.95
0.09
3.6
3.5
3.14
8.23
mg/mmol
1.27
23
311
5
60
0.83
0.08
3.2
2.8
—
—
—
0
0
27
254
1.07
0.08
2.1
1.7
—
—
—
0
0
11
98
1.13
0.08
1.5
1.3
—
—
—
0
0
39
373
1.05
0.07
1.3
1.3
—
—
—
0
0
9
85
1.06
0.07
2.2
1.6
—
—
—
0
0
8
93
0.86
0.07
2.6
1.6
—
—
—
0
0
13
142
0.91
0.06
1.3
1.4
320.85
304.16
mu/l
0.05
13
125
113
1149
0.97
0.06
2.7
3.1
0.00
0.00
estimate
—
8
225
25
237
1.06
0.06
1.3
1.2
174.38
150.10
iu/ml
0.13
13
103
37
356
1.05
0.05
2.4
2.0
—
—
—
0
0
118
1162
1.03
0.05
2.7
3.1
0.00
0.00
estimate
—
6
208
49
504
0.97
0.05
1.3
1.3
6.02
10.07
u/ml
0.53
19
217
178
1796
0.98
0.04
3.4
3.6
9.15
9.50
mm/h
0.25
171
1682
50
513
0.97
0.04
1.5
1.3
25.55
28.63
iu/ml
0.14
12
172
12
112
1.07
0.03
1.7
1.4
—
—
—
0
0
11
118
0.93
0.03
1.3
1.4
—
—
—
0
0
15
157
0.95
0.01
1.1
1.4
—
—
—
0
0
232
2327
0.99
0.01
3.7
3.8
5.67
5.69
mmol/l
0.10
221
2186
11
104
1.06
0.01
1.5
2.2
81.70
71.08
e9/l
—
6
78
49
484
1.01
0.00
3.1
3.2
20.29
350.89
mg/l
0.95
28
308
50
506
0.99
0.00
2.0
2.0
2.57
2.77
mg/l
0.21
42
438
65
644
1.01
0.00
1.8
1.6
1.36
1.39
mmol/l
0.13
60
560
12
119
1.01
0.00
1.7
1.4
—
—
—
0
0
12
119
1.01
0.00
1.7
1.4
—
—
—
0
0
14
143
0.98
0.00
1.0
1.2
—
—
—
0
0
31
306
1.01
0.00
1.4
1.2
—
—
—
0
0
115
1153
1.00
0.00
4.2
4.3
0.00
0.00
estimate
—
8
216
8
86
0.93
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
2.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.02
—
0
8
0
6
0.00
-0.00
0.0
3.0
—
15.33
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.4
—
7.18
—
0
8
0
7
0.00
-0.00
0.0
4.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
5
59
0.84
-0.00
1.0
1.1
—
—
—
0
0
12
120
1.00
-0.00
1.7
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_PROPHYLACT_SURGE – Prophylactic surgery

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).