No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
376 |
4. Check minimum number of eventsNone |
376 |
5. Include endpointsNone |
376 |
6. Filter based on genotype QC (FinnGen only) |
376 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M67
- Name in latin
- Hypertrophia membranae synovialis non alibi classificata
Similar endpoints
↥List of similar endpoints to
Synovial hypertrophy, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3056 | 1552 | 1498 |
| Only index persons | 3008 | 1538 | 1470 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.06 | 0.06 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 36.05 | 35.31 | 36.81 |
| Only index persons | 36.00 | 35.29 | 36.74 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 376 | 221 | 155 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.07 |
| Median age at first event (years) | 38.14 | 36.49 | 40.48 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 343
- Matched controls
- 3430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M67.2
ICD-10 Finland
Synovial hypertrophy, not elsewhere classified
+∞
323.0
343
*
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
127.4
142.8
147
20
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
17.6
55.8
91
69
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
9.1
42.7
98
145
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
61.2
37.3
43
8
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
13.3
33.9
61
55
M22.4
ICD-10 Finland
Chondromalacia patellae
15.9
31.5
52
38
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
6.8
30.9
85
159
M25.5
ICD-10 Finland
Pain in joint
4.2
29.5
142
493
M79.6
ICD-10 Finland
Pain in limb
3.9
25.9
136
497
M17.1
ICD-10 Finland
Other primary gonarthrosis
5.1
25.9
92
231
M01AH05
ATC
etoricoxib; oral
3.1
21.1
234
1410
M01AX05
ATC
glucosamine; oral
4.4
19.1
75
204
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
20.2
19.0
28
15
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
18.5
183
992
N02AX02
ATC
tramadol; systemic, rectal
2.9
17.9
149
720
M23.8
ICD-10 Finland
Other internal derangements of knee
9.9
17.9
36
40
M01AB05
ATC
diclofenac; systemic, rectal
2.8
17.4
250
1671
N03AX12
ATC
gabapentin; oral
4.2
15.9
65
182
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
5.1
15.9
52
116
S83.2
ICD-10 Finland
Tear of meniscus, current
5.3
14.8
46
97
N02AJ06
ATC
codeine and paracetamol; systemic
2.6
14.5
146
766
M67.4
ICD-10 Finland
Ganglion
10.1
14.2
28
30
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.4
14.0
73
250
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
11.6
13.7
25
23
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
+∞
13.6
13
*
M67.8
ICD-10 Finland
Other specified disorders of synovium and tendon
145.5
13.5
14
*
S18
ICPC
Laceration/cut
2.5
13.2
141
753
M01AX17
ATC
nimesulide; oral
3.0
12.8
85
344
M01AE02
ATC
naproxen; oral, rectal
2.3
12.7
210
1388
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.4
12.6
38
77
M03BX02
ATC
tizanidine; oral
2.3
12.5
229
1585
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
5.7
12.2
35
67
L15
ICPC
Knee symptom/complaint
3.0
11.7
74
289
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
124.0
11.5
12
*
M01AC06
ATC
meloxicam; systemic, rectal
2.4
11.2
124
662
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
44.8
11.0
13
*
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
8.4
10.8
23
29
M02AA07
ATC
piroxicam; topical
2.4
10.8
118
624
N03AX16
ATC
pregabalin; oral
2.8
10.7
79
336
M54.5
ICD-10 Finland
Low back pain
2.3
10.1
116
625
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.3
10.0
52
176
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.5
9.9
35
85
M01AH01
ATC
celecoxib; oral (coxibs)
2.9
9.8
64
254
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.9
9.7
40
112
H02AB06
ATC
prednisolone; systemic
2.1
9.7
153
948
L03
ICPC
Low back symptom/complaint
2.5
9.6
83
386
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.8
9.6
40
114
M01AH02
ATC
rofecoxib; oral
3.5
9.4
44
138
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
9.1
120
684
M01AE01
ATC
ibuprofen; systemic, rectal
3.2
9.1
320
2781
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
37.8
9.1
11
*
N02BE01
ATC
paracetamol; systemic, rectal
2.3
9.0
285
2325
1220
FHL
Arthroscopy
6.2
8.9
23
39
ZXA00
NOMESCO Finland
Right side
2.4
8.8
81
387
M77.1
ICD-10 Finland
Lateral epicondylitis
4.0
8.5
33
88
NGF10
NOMESCO Finland
Total synovectomy of knee, open
+∞
8.4
8
*
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
+∞
8.4
8
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
7.1
8.2
19
28
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
8.1
115
669
WX320
NOMESCO Finland
Spinalanesthesy
2.4
8.1
77
375
M02AA10
ATC
ketoprofen; topical
2.8
7.9
52
204
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.8
7.9
50
194
J01AA02
ATC
doxycycline; systemic
2.0
7.7
256
2038
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
7.7
88
466
R03AC02
ATC
salbutamol; inhalant
1.9
7.6
179
1254
WX110
NOMESCO Finland
Local anesthesy
1.9
7.5
244
1917
A02BC05
ATC
esomeprazole; systemic
2.0
7.5
127
790
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
7.1
7.4
17
25
M03BC01
ATC
orphenadrine (citrate); systemic
2.1
7.2
91
502
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
6.8
7.2
17
26
S60.0
ICD-10 Finland
Contusion of finger(s) without damage to nail
5.9
7.2
19
34
NGE15
NOMESCO Finland
Incision fo capsule of knee joint, arthroscopic
20.5
7.2
10
5
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
7.1
88
479
M48.0
ICD-10 Finland
Spinal stenosis
3.5
7.1
32
98
M09AX01
ATC
hyaluronic acid; parenteral
5.7
7.0
19
35
M79.5
ICD-10 Finland
Residual foreign body in soft tissue
14.1
6.9
11
8
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
6.3
6.9
17
28
J45.9
ICD-10 Finland
Asthma, unspecified
2.5
6.8
55
244
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
40.9
6.8
8
*
M94.2
ICD-10 Finland
Chondromalacia
17.1
6.8
10
6
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.8
6.7
43
168
NBG10
NOMESCO Finland
Acromioplastia
23.0
6.7
9
*
ZXA05
NOMESCO Finland
Left side
2.2
6.7
72
367
R51.80
ICD-10 Finland
Headache
2.5
6.7
54
239
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
6.6
80
432
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.4
6.6
22
52
L17
ICPC
Foot/toe symptom/complaint
2.2
6.6
73
378
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.8
6.2
25
70
J01DB01
ATC
cefalexin; oral
2.0
6.2
277
2337
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
6.2
59
287
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.2
6.1
30
99
L08
ICPC
Shoulder symptom/complaint
2.4
6.1
53
245
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
10.3
6.1
11
11
W22
ICD-10 Finland
Striking against or struck by other object(s)
3.3
6.1
29
94
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
90
439
2.38
10.70
1.4
1.2
16.0
34.8
iu/ml
2.02
34
137
83
414
2.29
9.27
1.4
1.2
15.3
11.2
u/ml
0.12
27
175
20
45
4.64
8.47
1.7
1.4
—
—
—
0
0
261
2034
1.93
7.78
4.7
3.4
9.8
9.9
mm/h
0.03
251
1897
102
632
1.84
6.07
2.4
2.7
325.0
8159.4
umol/l
3.09
92
562
200
1538
1.64
5.27
4.1
4.7
6.6
6.6
mmol/l
0.02
186
1401
314
2737
1.89
5.05
4.9
4.2
1.8
1.8
mu/l
0.07
292
2535
269
2247
1.69
4.98
4.2
3.7
14.7
14.5
pmol/l
0.74
252
2060
338
3029
2.15
4.90
13.5
10.6
19.6
22.6
mg/l
0.92
266
2290
47
244
2.06
4.65
10.6
16.0
1.1
1.2
inr
0.41
14
38
336
3035
2.01
4.28
12.9
11.7
139.7
139.7
mmol/l
0.06
327
2954
78
500
1.71
4.00
1.4
1.4
19.4
20.5
nmol/l
0.31
69
433
35
174
2.12
3.89
2.2
2.4
7.5
12.3
au/ml
—
5
9
138
1025
1.55
3.88
4.8
4.8
37.3
36.4
g/l
1.16
133
968
335
3048
1.91
3.80
13.1
11.9
4.0
3.9
mmol/l
0.42
326
2959
21
86
2.53
3.62
1.8
1.8
—
—
—
0
0
164
1294
1.47
3.34
4.1
4.0
—
—
—
0
0
96
677
1.56
3.33
1.3
1.2
2.4
2.0
u/ml
0.10
23
187
42
237
1.87
3.30
3.3
2.8
—
—
—
0
0
170
1364
1.45
3.11
5.0
6.5
10.5
10.5
umol/l
0.02
164
1303
111
821
1.50
3.07
2.0
2.3
53.1
57.6
u/l
0.83
104
768
36
198
1.90
3.06
3.2
2.5
71.6
71.0
ml/min/173m2
—
5
80
17
69
2.53
3.00
1.4
1.3
391.5
360.1
ug/g
0.26
12
38
84
590
1.55
2.95
1.6
1.6
0.7
1.0
mg/l
1.34
61
434
13
47
2.83
2.84
2.2
1.2
—
—
—
0
0
121
924
1.46
2.82
1.9
1.7
100.8
96.1
pmol/l
0.56
71
485
54
348
1.64
2.71
1.8
1.9
—
—
—
0
0
23
114
2.08
2.62
1.8
2.4
39.1
37.9
u/l
0.14
23
105
12
44
2.78
2.57
2.0
1.3
—
1.0
—
0
5
27
145
1.93
2.49
2.0
2.8
108.3
116.2
ng/l
0.08
19
131
21
103
2.10
2.47
1.9
1.6
—
—
—
0
0
161
1321
1.38
2.44
2.8
2.6
97.1
118.0
ug/l
0.83
154
1221
117
910
1.41
2.42
2.8
2.9
38.9
31.9
ng/l
0.22
67
525
11
40
2.80
2.39
1.1
1.3
—
—
—
0
0
18
84
2.20
2.39
1.6
1.8
—
—
—
0
0
148
1203
1.38
2.35
7.0
7.3
1.2
1.2
mmol/l
2.14
124
1024
47
305
1.62
2.31
1.8
2.3
23.2
24.0
%
0.18
41
263
63
438
1.53
2.31
3.6
3.2
156.7
580.6
ng/l
1.39
39
324
20
99
2.08
2.30
1.3
1.7
—
—
—
0
0
136
1094
1.38
2.29
2.6
2.2
74.5
73.9
nmol/l
0.11
131
1010
6
13
4.67
2.28
1.0
1.2
—
—
—
0
0
243
2148
1.37
2.23
7.4
7.0
70.7
76.5
u/l
2.40
233
2033
91
686
1.43
2.23
2.0
2.1
134.9
206.7
u/l
1.64
91
645
132
1063
1.37
2.20
5.6
6.5
1.2
1.2
mmol/l
1.91
124
970
6
14
4.34
2.16
1.0
1.2
—
—
—
0
0
247
2195
1.37
2.15
3.2
2.9
37.9
46.8
u/l
2.48
236
2090
18
90
2.05
2.04
1.9
2.1
—
—
—
0
0
24
134
1.84
2.00
6.4
9.0
24.3
24.9
mmol/l
0.28
24
134
28
165
1.75
1.97
2.0
1.5
—
—
—
0
0
313
2910
1.45
1.96
4.0
3.7
6.0
5.8
mmol/l
0.67
294
2709
8
27
3.00
1.94
1.9
2.3
—
—
—
0
0
39
253
1.60
1.94
2.3
2.1
12.9
13.8
nmol/l
0.35
34
233
89
686
1.39
1.91
3.7
2.6
0.2
0.4
e6/l
2.17
67
499
259
2339
1.34
1.90
3.6
3.3
—
—
—
0
0
310
2884
1.43
1.87
10.9
9.5
89.9
88.2
ml/min/173m2
0.79
265
2337
13
59
2.25
1.86
1.5
1.3
—
—
—
0
0
5
12
4.21
1.83
1.2
1.2
—
—
—
0
0
346
3298
1.62
1.76
9.9
8.7
28.7
28.0
u/l
0.27
335
3203
314
2937
1.42
1.75
3.9
3.5
1.4
1.3
mmol/l
1.86
294
2769
78
598
1.38
1.72
2.4
2.0
2.3
2.8
mg/l
1.60
68
497
5
13
3.88
1.72
1.0
1.1
—
—
—
0
0
187
1630
1.29
1.70
8.0
9.3
4.2
4.0
e9/l
0.66
164
1424
323
3049
1.42
1.58
4.2
3.9
4.8
4.8
mmol/l
0.21
302
2890
12
57
2.14
1.56
1.6
1.8
—
—
—
0
0
322
3040
1.41
1.56
4.1
3.8
1.4
1.5
mmol/l
2.11
302
2870
101
820
1.32
1.53
2.5
3.5
2.4
2.4
mmol/l
0.17
85
738
35
236
1.53
1.51
1.7
1.8
—
—
—
0
0
35
237
1.53
1.48
1.7
1.7
—
—
—
0
0
33
476
0.66
1.45
2.7
2.7
0.5
0.7
ug/l
1.57
18
279
289
2693
1.32
1.45
5.0
4.7
38.7
38.8
mmol/mol
0.07
272
2551
86
693
1.31
1.37
1.7
1.5
—
—
—
0
0
5
17
2.97
1.36
3.2
1.2
—
—
—
0
0
107
890
1.28
1.35
3.6
2.8
—
—
—
0
0
324
3083
1.37
1.30
4.4
4.2
3.0
2.9
mmol/l
0.97
303
2905
5
118
0.42
1.27
3.6
2.3
1.0
1.3
%
—
5
118
49
367
1.39
1.26
1.7
1.5
1119.2
1125.3
nmol/l
0.02
40
271
8
36
2.25
1.25
1.8
1.4
—
—
—
0
0
8
36
2.25
1.25
1.7
1.4
—
—
—
0
0
8
37
2.19
1.22
1.7
1.4
—
—
—
0
0
8
37
2.19
1.22
1.8
1.4
—
—
—
0
0
8
37
2.19
1.22
1.8
1.4
—
—
—
0
0
25
166
1.54
1.18
1.1
1.0
—
—
—
0
0
10
184
0.53
1.17
1.3
1.5
—
—
—
0
0
5
20
2.52
1.15
1.0
1.6
—
—
—
0
0
285
2682
1.26
1.12
13.3
13.1
13.4
13.5
%
1.31
277
2634
5
21
2.40
1.09
1.0
1.4
5.3
6.7
mmol/l
—
5
21
10
52
1.95
1.07
1.9
1.2
—
—
—
0
0
17
106
1.63
1.04
5.1
3.8
23.0
24.0
mmol/l
0.76
17
97
17
261
0.63
1.03
1.5
1.5
—
—
—
0
0
71
582
1.27
1.01
3.5
2.9
1.0
1.0
kg/l
0.40
15
80
151
1347
1.20
0.97
3.3
2.9
0.0
0.0
estimate
0.00
29
244
9
50
1.82
0.97
2.9
1.8
13.3
12.9
%
—
9
50
19
125
1.55
0.96
1.8
1.7
—
—
—
0
0
9
51
1.78
0.95
1.0
1.2
—
—
—
0
0
84
713
1.23
0.89
4.2
3.9
10.2
10.9
mg/mmol
0.05
56
463
8
45
1.79
0.84
3.6
1.6
—
—
—
0
0
46
571
0.78
0.84
1.7
1.5
—
—
—
0
0
6
32
1.89
0.82
1.0
1.3
—
—
—
0
0
57
469
1.25
0.80
1.4
1.8
1.3
1.4
%
0.47
48
422
20
140
1.45
0.78
1.8
1.3
—
—
—
0
0
28
210
1.36
0.76
3.8
3.7
1.8
1.7
mmol/l
0.05
20
165
12
77
1.58
0.69
1.2
1.1
—
—
—
0
0
29
223
1.33
0.69
1.2
1.3
113.1
172.2
iu/ml
—
9
95
148
1353
1.15
0.67
4.5
4.2
0.0
0.0
estimate
0.00
35
247
7
44
1.60
0.65
2.4
1.7
—
—
—
0
0
5
29
1.73
0.64
1.0
1.8
—
—
—
0
0
48
400
1.23
0.62
3.6
2.8
2.4
2.4
mmol/l
0.54
39
351
149
1369
1.15
0.62
3.4
3.0
0.0
0.0
estimate
0.00
33
235
11
163
0.67
0.61
1.6
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
12
80
1.52
0.60
1.5
1.3
—
—
—
0
0
7
111
0.62
0.59
2.4
3.5
49.0
51.8
%
—
7
111
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
2.2
—
—
—
0
0
76
668
1.17
0.57
3.8
3.2
0.0
0.0
estimate
0.00
33
244
8
55
1.46
0.56
1.1
1.4
20.5
24.6
u/l
—
8
49
18
133
1.37
0.56
1.4
2.6
0.3
0.1
e6/l
0.66
18
128
6
37
1.63
0.56
2.0
1.4
—
—
—
0
0
6
39
1.55
0.53
1.0
1.1
—
—
—
0
0
6
97
0.61
0.52
1.7
2.1
90.7
91.5
%
—
6
89
47
399
1.20
0.52
3.1
2.4
3.0
2.4
e6/l
0.29
29
210
37
309
1.22
0.49
2.4
2.6
6.1
6.8
umol/l
0.26
32
260
56
488
1.17
0.48
1.6
1.6
484.2
26157824.3
pmol/l
0.76
48
432
37
314
1.20
0.43
4.2
3.8
31.3
31.3
%
0.00
28
221
0
16
0.00
0.41
0.0
2.1
—
—
—
0
0
34
399
0.84
0.41
1.6
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
2.0
—
0
7
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
6
42
1.44
0.35
1.2
1.0
1.5
1.4
g/l
—
6
36
58
643
0.88
0.35
3.7
3.6
25.8
21.0
%
0.79
20
262
6
44
1.37
0.34
1.0
1.1
—
—
—
0
0
84
773
1.11
0.34
3.9
3.9
1.3
2.3
ug/l
1.51
77
702
6
87
0.68
0.33
1.3
1.5
—
—
—
0
0
6
89
0.67
0.33
7.8
3.1
35.3
2503.6
u/ml
—
6
76
115
1079
1.09
0.32
3.4
3.0
—
—
—
0
0
12
153
0.78
0.31
1.6
1.4
—
—
—
0
0
12
153
0.78
0.31
1.6
1.4
—
—
—
0
0
12
153
0.78
0.31
1.6
1.4
—
—
—
0
0
12
153
0.78
0.31
1.6
1.4
—
—
—
0
0
7
100
0.69
0.31
1.4
1.8
—
—
—
0
0
47
421
1.13
0.30
3.0
2.3
0.2
1.0
e6/l
4.72
29
229
59
538
1.11
0.29
2.4
3.2
896.2
884.7
ng/l
0.02
47
432
9
117
0.76
0.28
1.2
1.4
—
—
—
0
0
29
253
1.16
0.27
6.8
10.7
0.2
1.1
mmol/l
0.41
20
196
70
651
1.09
0.24
2.6
2.1
—
—
—
0
0
18
152
1.19
0.24
4.7
3.6
5.3
5.2
kpa
0.46
18
143
15
178
0.84
0.22
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
67.6
—
0
12
5
43
1.16
0.21
1.0
1.0
—
—
—
0
0
25
280
0.89
0.19
5.8
6.0
—
—
—
0
0
305
3008
1.07
0.19
11.9
11.6
39.9
40.7
%
0.76
237
2410
7
58
1.21
0.18
2.6
1.6
—
—
—
0
0
8
72
1.11
0.16
2.6
2.6
—
—
—
0
0
15
130
1.16
0.16
1.3
1.5
132.7
257.2
miu/ml
—
9
65
10
119
0.84
0.15
1.6
1.4
—
—
—
0
0
28
306
0.91
0.15
2.3
2.0
—
—
—
0
0
7
87
0.80
0.14
1.0
1.1
—
—
—
0
0
10
116
0.86
0.12
1.4
1.6
—
—
—
0
0
46
485
0.94
0.11
1.5
2.0
—
—
—
0
0
13
146
0.89
0.10
1.2
1.6
—
—
—
0
0
5
45
1.11
0.10
1.4
1.0
—
—
—
0
0
75
775
0.96
0.09
1.7
1.6
1.6
1.4
mmol/l
0.62
62
663
6
57
1.05
0.08
4.5
3.3
26.1
59.8
mg/l
—
6
45
6
57
1.05
0.08
4.5
3.2
—
1.2
—
0
6
6
57
1.05
0.08
4.5
3.3
19.1
26.6
mg/l
—
6
46
7
64
1.10
0.08
5.4
1.8
—
—
—
0
0
7
67
1.05
0.08
1.6
1.8
—
—
—
0
0
52
540
0.96
0.08
1.8
2.1
—
—
—
0
0
26
245
1.07
0.07
2.2
1.9
—
—
—
0
0
7
81
0.86
0.07
1.3
1.3
—
—
—
0
0
14
128
1.10
0.07
9.1
12.6
95.5
93.9
%
1.42
14
128
17
180
0.94
0.04
3.3
3.0
4.7
4.7
kpa
0.06
17
174
16
163
0.98
0.00
1.1
2.3
17572.4
2369.0
u/l
—
5
70
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
5.5
—
—
—
0
0
5
52
0.96
0.00
1.8
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
8
87
0.92
0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.7
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_SYNOHYPERTROPH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SYNOHYPERTROPH | 0.855 [0.66, 1.11] | 0.242 |
| Birth year | 0.99 [0.98, 1.0] | 0.031 |
During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 1348 females with M13_SYNOHYPERTROPH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SYNOHYPERTROPH | 0.647 [0.51, 0.83] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 1281 males with M13_SYNOHYPERTROPH died.
Mortality risk
Mortality risk for people of age
years, who have M13_SYNOHYPERTROPH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.068% | 0.126% |
| 5 | 0.399% | 0.722% |
| 10 | 0.962% | 1.892% |
| 15 | 1.923% | 3.781% |
| 20 | 3.398% | 6.383% |
Relationships between endpoints
↥Index endpoint: M13_SYNOHYPERTROPH – Synovial hypertrophy, not elsewhere classified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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