Benign neoplasm: Mesothelial tissue of other sites/unspecified

CD2_BENIGN_MESOTHELIAL_NOS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D19.7&, D19.9& Cause of death: ICD-10 — D19.7&, D19.9& 2 out of 7 registries used, show all original rules.	22
4. Check minimum number of events None	22
5. Include endpoints None	22
6. Filter based on genotype QC (FinnGen only)	22

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	CD2_BENIGN_MESOTHELIAL_NOS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D19[7\|9]
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D19[7\|9]
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Mesothelial tissue of other sites/unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Mesothelial tissue of other sites/unspecified

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	150	89	61
Only index persons	137	82	55
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	47.60	48.89
Only index persons	47.07	46.08	48.54

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	22	17	5
Unadjusted period prevalence (%)	0.00	0.01	0.00
Median age at first event (years)	44.97	40.80	59.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3048689) Calprotectin [Mass/mass] in Stool

4.38

2.18

3.6

1.2

39.63

40.08

ug/g

—

(3022145) Colonoscopy Study observation

4.17

1.89

1.3

1.5

—

(3025941) Bacteria identified in Stool by Culture

4.29

1.71

1.0

1.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

2.61

1.28

3.5

3.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

2.61

1.24

2.6

3.0

—

(3042936) Bacteria identified in Isolate by Culture

2.92

1.22

1.6

1.9

—

(3041096) Erythrocytes [Presence] in Urine by Automated

2.34

1.16

3.9

3.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.67

1.03

1.5

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

2.27

0.98

1.8

1.9

63.20

77.19

nmol/l

1.00

(36304419) Bacteria [Presence] in Urine

2.09

0.81

2.9

2.8

—

(1761868) Lipid panel - Serum or Plasma

1.72

0.64

2.8

2.5

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.64

0.0

1.4

—

(3026008) Bacteria identified in Urine by Culture

1.71

0.55

4.7

2.9

—

(3002030) Lymphocytes/100 leukocytes in Blood

0.60

0.44

7.7

3.9

30.83

30.28

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.43

0.0

1.3

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

0.00

0.42

0.0

5.8

—

229.18

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.63

0.40

1.5

1.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.59

0.40

1.3

1.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.50

0.38

2.0

2.3

—

(42870588) Differential panel, method unspecified - Blood

1.47

0.36

5.3

3.5

—

(3015736) pH of Urine

1.52

0.34

2.0

3.5

—

(3044640) Blood type and Crossmatch panel - Blood

1.42

0.33

1.9

2.2

—

(3021589) Normoblasts [#/volume] in Blood

0.63

0.32

24.6

6.9

0.00

e9/l

—

(3001604) Monocytes [#/volume] in Blood

0.63

0.31

7.7

4.7

0.72

0.57

e9/l

—

(3022096) Basophils/100 leukocytes in Blood

0.68

0.31

7.7

3.7

0.33

0.65

—

(3013707) Erythrocyte sedimentation rate by Westergren method

128

1.54

0.30

4.7

3.6

9.00

11.02

mm/h

0.54

116

(3037467) Urinalysis macro (dipstick) panel - Urine

120

1.46

0.30

5.9

3.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

1.41

0.25

2.2

4.0

0.54

9.06

mg/mmol

—

(3009508) Creatinine [Moles/volume] in Urine

1.36

0.25

1.6

2.7

8.30

8.44

mmol/l

—

(3013512) EKG study

1.38

0.23

3.0

3.6

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.22

0.0

1.2

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.22

0.0

1.5

—

(3024354) Oxygen [Partial pressure] in Venous blood

0.00

0.22

0.0

2.7

—

3.83

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.22

0.0

1.3

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.22

0.0

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

0.00

0.22

0.0

7.1

—

24.30

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.22

0.0

1.3

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.22

0.0

1.3

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.22

0.0

1.3

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.22

0.0

1.3

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.22

0.0

1.5

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.22

0.0

1.2

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

0.00

0.22

0.0

3.2

—

129.20

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.22

0.0

1.0

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

0.00

0.22

0.0

2.8

—

5.69

—

(3000991) Gas panel - Venous blood

0.00

0.22

0.0

7.4

—

(3012544) pH of Venous blood

0.00

0.21

0.0

3.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

6.6

—

0.83

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3013115) Eosinophils [#/volume] in Blood

0.71

0.19

6.9

4.6

0.14

0.17

e9/l

—

(40768804) Tissue Pathology biopsy report

0.76

0.19

1.9

1.7

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

173

0.92

0.10

12.7

11.0

99.74

86.50

ml/min/173m2

1.55

139

(3003338) MCHC [Mass/volume]

150

1.24

0.09

9.8

15.4

334.69

331.43

g/l

0.92

150

(3006504) Eosinophils/100 leukocytes in Blood

0.82

0.09

6.7

3.8

1.91

2.62

—

(3018010) Neutrophils/100 leukocytes in Blood

0.79

0.09

6.0

3.9

57.10

55.13

—

(3019069) Monocytes/100 leukocytes in Blood

0.79

0.09

6.6

4.0

8.09

8.70

—

(3044889) 12 lead EKG panel

121

0.82

0.08

4.2

3.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

135

0.91

0.08

3.4

3.2

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.00

0.0

3.3

—

0.87

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

3.4

—

22.71

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.7

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

0.96

0.00

7.4

3.8

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

1.1

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

0.00

0.0

8.9

—

1.71

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.0

2.4

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3020891) Body temperature

0.00

0.0

3.3

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

0.00

0.0

8.9

—

0.57

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

0.00

0.0

3.0

—

25.60

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

1.06

0.00

2.9

2.7

79.90

72.25

ug/l

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

0.00

0.0

12.0

—

23.80

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.0

3.8

—

10.40

—

(40768443) Skin Pathology biopsy report

0.00

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

9.00

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

100

1.00

0.00

3.2

4.5

6.75

6.30

mmol/l

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

2.0

—

50.40

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

0.0

1.6

—

90.00

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.03

0.00

2.0

1.4

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(3036489) Thrombin time

0.00

0.0

1.6

—

22.60

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.4

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

4.12

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.0

3.8

—

4.62

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

286.20

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

2.20

—

(3012501) Base excess in Blood by calculation

0.00

0.0

3.8

—

2.98

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

1.6

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.0

3.6

—

(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting

0.00

-0.00

0.0

1.0

—

0.81

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

-0.00

0.0

1.9

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

-0.00

0.0

1.3

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

-0.00

0.0

2.5

—

38.04

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.1

—

23.49

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(1616796) Gas panel - Central venous blood

0.00

-0.00

0.0

1.3

—

(3049717) Cytology report of Urine Cyto stain

0.00

-0.00

0.0

1.3

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

-0.00

0.0

3.0

—

2.00

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

-0.00

0.0

2.4

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.1

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_MESOTHELIAL_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MESOTHELIAL_NOS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_MESOTHELIAL_NOS – Benign neoplasm: Mesothelial tissue of other sites/unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Mesothelial tissue of other sites/unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints