No definition available.
Other congenital malformations of peripheral vascular system
EFO MESH Endpoint Browser PheWeb
Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
523 |
4. Check minimum number of eventsNone |
523 |
5. Include endpointsNone |
523 |
6. Filter based on genotype QC (FinnGen only) |
507 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q2
- Name in latin
- Aliae malformationes congenitae systematis vascularis peripherici
Similar endpoints
↥List of similar endpoints to
Other congenital malformations of peripheral vascular system
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of the circulatory system
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3588 | 2038 | 1530 |
| Only index persons | 3103 | 1810 | 1293 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.06 | 0.07 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 27.46 | 30.77 | 22.92 |
| Only index persons | 31.03 | 32.77 | 28.60 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 507 | 339 | 168 |
| Unadjusted period prevalence (%) | 0.11 | 0.12 | 0.08 |
| Median age at first event (years) | 45.50 | 42.14 | 52.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 523
- Matched controls
- 5230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q27.3
ICD-10 Finland
Peripheral arteriovenous malformation
+∞
216.1
192
*
D18.0
ICD-10 Finland
Haemangioma, any site
38.8
211.1
136
47
Q27.4
ICD-10 Finland
Congenital phlebectasia
+∞
191.8
172
*
Q27.9
ICD-10 Finland
Congenital malformation of peripheral vascular system, unspecified
+∞
127.4
117
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
16.5
119.6
109
82
Q27.88
ICD-10 Finland
Other specified congenital malformation of peripheral vascular system
+∞
104.8
97
*
QX3LT
NOMESCO Finland
Subcutaneous sclerotherapy
+∞
61.7
58
*
XX6KT
NOMESCO Finland
Other sclerotherapy
216.1
39.4
40
*
D18.1
ICD-10 Finland
Lymphangioma, any site
+∞
32.6
31
*
Z2221
NOMESCO Finland
Medical doctor
2.9
28.5
206
969
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
27.1
162
685
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
9.2
26.6
33
38
ZXD10
NOMESCO Finland
Scheduled procedure
2.7
26.4
243
1282
Q27.0
ICD-10 Finland
Congenital absence and hypoplasia of umbilical artery
+∞
26.3
25
*
Q82.50
ICD-10 Finland
Naevus flammeus
131.0
23.8
25
*
PG1HT
NOMESCO Finland
Extensive endovascular embolisation of arterio-venous malformation not elsewhere classified
+∞
23.1
22
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
21.5
219
1185
XX4BW, ,
NOMESCO Finland
52.4
21.3
25
5
EP1LT
NOMESCO Finland
Percutaneous sclerotherapy of vascular malformation of head and neck
+∞
21.0
20
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.4
20.1
34
56
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
20.0
92
330
R4110
NOMESCO Finland
Physiotherapy
2.5
19.5
173
872
Q87.21
ICD-10 Finland
Klippel-Trénaunay-Weber syndrome
+∞
18.9
18
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
5.3
17.9
37
74
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.3
17.4
36
72
Z3226
NOMESCO Finland
Physiotherapist
2.6
17.0
123
559
JN5LT
NOMESCO Finland
Sclerotherapy with direct puncture body area
+∞
16.8
16
*
PG1JT
NOMESCO Finland
Very extensive endovascular embolisation of arterio-venous malformation not elsewhere classified
+∞
16.8
16
*
2280A
ICD-9 Finland
Haemangioma and lymphangioma, any site, Haemangioma, any site
175.4
16.6
17
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
16.1
161
846
ZXC12
NOMESCO Finland
Pulse colorlaser
62.0
15.9
18
*
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
11.8
15.4
28
25
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
25.9
14.8
20
8
22700
ICD-8 Finland
Haemangioma and lymphangioma, Haemangioma
82.5
14.6
16
*
ZXA05
NOMESCO Finland
Left side
2.4
14.5
125
612
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
6.7
13.7
22
34
PG1GT
NOMESCO Finland
Endovascular embolisation of arterio-venous malformation with radiological guidance not elsewhere classified
+∞
13.6
13
*
Q27.2
ICD-10 Finland
Other congenital malformations of renal artery
+∞
13.6
13
*
ZXE00
NOMESCO Finland
One hour or less
2.0
13.4
229
1458
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
51.3
12.9
15
*
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
5.3
12.3
25
49
Z31.5
ICD-10 Finland
Genetic counselling
3.1
12.0
53
184
WX402
NOMESCO Finland
General anaesthesia
2.1
12.0
132
710
Z3231
NOMESCO Finland
Registered nurse
2.0
11.6
162
951
Q27.1
ICD-10 Finland
Congenital renal artery stenosis
+∞
11.5
11
*
QX3KT, ,
NOMESCO Finland
+∞
11.5
11
*
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
15.5
11.4
18
12
ZXA00
NOMESCO Finland
Right side
2.1
11.3
128
694
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
13.1
11.2
19
15
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.4
10.7
21
40
PB1AC
NOMESCO Finland
Angiography of upper extremity with X-ray
112.2
10.5
11
*
Q27.80
ICD-10 Finland
Congenital stricture, artery
+∞
10.4
10
*
I77.0
ICD-10 Finland
Arteriovenous fistula, acquired
+∞
10.4
10
*
Q28.8
ICD-10 Finland
Other specified congenital malformations of circulatory system
+∞
10.4
10
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
10.3
85
404
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.4
10.2
26
62
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
17.1
9.9
15
9
WX002
NOMESCO Finland
Sedation and analgesia
2.2
9.8
96
490
I78.0
ICD-10 Finland
Hereditary haemorrhagic telangiectasia
56.1
9.7
11
*
PG1CG
NOMESCO Finland
Extensive MRI examination of vasculature with high intensity magnet not elsewhere classified
101.8
9.4
10
*
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
30.6
9.4
12
*
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
30.6
9.4
12
*
PG1DG
NOMESCO Finland
Very extensive MRI examination of vasculature with high intensity magnet not elsewhere classified
+∞
9.4
9
*
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
+∞
9.4
9
*
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
+∞
9.4
9
*
PA5AC
NOMESCO Finland
Angiography of arteries to the face with X-ray
+∞
9.4
9
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.1
9.4
39
131
ZXA10
NOMESCO Finland
Bilateral
2.1
9.2
96
502
H02AB06
ATC
prednisolone; systemic
1.8
9.1
226
1572
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
9.1
79
384
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
4.7
8.7
20
44
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
5.0
8.4
18
37
I87.8
ICD-10 Finland
Other specified disorders of veins
+∞
8.4
8
*
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
+∞
8.4
8
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
7.3
8.3
19
27
A46
ICD-10 Finland
Erysipelas
2.3
8.2
64
296
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.8
8.1
40
148
ZXD20
NOMESCO Finland
Day surgery
2.2
8.1
72
353
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.5
7.9
27
80
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
8.6
7.9
16
19
TQW40
NOMESCO Finland
Remowal of suture of skin
2.7
7.6
40
154
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
7.5
214
1524
ND1DG
NOMESCO Finland
Wrist and hand very extensive MRI examination with high intensity magnet
81.2
7.4
8
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
7.3
7
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
7.3
55
251
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.0
7.2
31
106
N03AX16
ATC
[U] pregabalin
1.9
7.2
107
631
PHT99
NOMESCO Finland
Injection of therapeutic or sclerosing agent into other vein
14.0
6.9
11
8
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.2
6.9
18
44
Q82.51
ICD-10 Finland
Naevus portwine
40.6
6.8
8
*
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
6.7
38
152
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
10.2
6.6
12
12
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
10.2
6.6
12
12
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.7
6.5
20
55
ZZA00
NOMESCO Finland
Split skin graft
5.4
6.5
18
34
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
7.5
6.4
14
19
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
70.7
6.4
7
*
I87.9
ICD-10 Finland
Disorder of vein, unspecified
14.5
6.4
10
7
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
6.3
68
358
WX203
NOMESCO Finland
Infraclavicular plexus blockade
3.9
6.3
18
47
I15.0
ICD-10 Finland
Renovascular hypertension
18.3
6.3
9
5
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
6.3
6
*
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
+∞
6.3
6
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
6.3
6
*
Q28.9
ICD-10 Finland
Congenital malformation of circulatory system, unspecified
+∞
6.3
6
*
I77.9
ICD-10 Finland
Disorder of arteries and arterioles, unspecified
+∞
6.3
6
*
FM2CE, ,
NOMESCO Finland
7.2
6.3
14
20
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
3.8
6.2
19
52
R4120
NOMESCO Finland
Occupational therapy
2.5
6.2
40
170
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
6.2
40
170
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
7.8
6.2
13
17
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
6.0
52
252
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
175
905
2.40
18.50
3.0
2.0
1.11
0.99
mg/l
0.26
133
690
36
73
5.22
17.13
1.4
1.2
2.22
2.68
u/ml
—
9
28
36
74
5.15
16.87
1.2
1.1
—
—
—
0
0
36
76
5.01
16.36
1.3
1.2
2.82
3.30
u/ml
0.19
22
33
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
27
23
12.31
15.23
1.3
1.0
106.59
126.52
%
0.87
27
23
174
963
2.21
15.18
2.4
2.2
—
—
—
0
0
26
24
11.34
14.15
1.1
1.0
95.10
96.09
%
—
10
11
235
1490
2.05
14.12
12.4
9.6
1.13
1.16
inr
0.31
69
486
24
20
12.52
13.72
1.4
1.8
148.13
128.70
%
0.34
24
20
25
23
11.35
13.65
1.1
1.0
84.78
100.20
%
—
9
10
271
1920
1.85
10.79
2.9
2.6
—
—
—
0
0
19
22
8.92
9.36
1.0
1.1
—
—
—
0
0
98
538
2.01
8.19
3.5
2.3
2.51
2.42
g/l
0.92
91
498
484
4329
2.58
7.92
14.7
11.5
23.56
20.84
mg/l
0.77
385
3275
91
496
2.01
7.74
3.8
2.4
21.28
23.92
%
1.18
82
428
450
3933
2.03
7.41
18.6
14.0
14.16
14.35
%
0.40
445
3880
243
1798
1.66
7.32
9.1
7.4
1.21
1.22
mmol/l
0.48
205
1561
310
2462
1.64
6.88
9.1
9.3
3.64
3.98
e9/l
2.06
266
2148
222
1626
1.63
6.83
10.2
7.1
1.21
1.22
mmol/l
0.65
199
1507
269
2074
1.61
6.65
7.1
6.2
55.85
55.50
%
0.20
261
1975
99
584
1.86
6.61
3.7
2.3
12.92
14.11
umol/l
0.92
94
542
28
96
3.03
6.53
1.3
1.3
—
—
—
0
0
208
1519
1.61
6.36
6.4
5.0
37.00
36.74
g/l
0.29
196
1438
470
4227
2.10
6.32
16.9
12.4
139.86
139.63
mmol/l
1.72
460
4109
270
2103
1.59
6.26
7.3
6.4
29.27
30.15
%
0.71
262
2008
67
354
2.02
6.18
4.6
6.9
1.36
1.50
mmol/l
0.10
54
285
516
4925
4.56
6.09
22.2
16.8
254.06
258.73
e9/l
0.89
505
4809
470
4241
2.07
6.04
16.9
12.5
3.91
3.94
mmol/l
1.31
458
4108
516
4932
4.45
5.77
22.2
16.8
4.49
4.54
e12/l
1.41
504
4805
516
4936
4.39
5.61
22.8
16.9
134.05
135.72
g/l
1.91
510
4877
389
3371
1.60
5.17
4.3
4.0
14.55
14.49
pmol/l
0.23
362
3113
188
1395
1.54
5.12
3.7
3.3
27.04
31.38
u/l
1.81
181
1334
148
1041
1.59
5.09
2.9
3.0
0.59
0.36
e6/l
0.45
106
771
279
2259
1.50
4.99
7.3
5.2
6.28
6.44
mmol/l
0.67
260
2077
139
972
1.59
4.88
3.7
2.3
3.22
2.87
mg/l
0.49
125
840
93
589
1.70
4.82
2.6
3.0
2.76
2.72
e6/l
0.01
44
314
514
4926
3.52
4.78
23.4
17.0
40.28
41.33
%
0.55
496
4682
52
279
1.96
4.61
3.1
2.3
70.31
73.27
ml/min/173m2
0.19
16
112
157
1147
1.53
4.49
3.0
3.1
14.04
109.00
e6/l
1.01
114
872
52
282
1.94
4.47
14.3
11.7
25.47
24.65
mmol/l
1.05
52
282
62
357
1.84
4.44
3.2
2.6
—
—
—
0
0
17
55
3.16
4.40
3.2
2.3
—
—
—
0
0
9
12
7.61
4.37
1.2
1.2
—
—
—
0
0
94
613
1.65
4.35
2.5
2.8
0.43
0.85
e6/l
1.65
47
336
352
3036
1.49
4.30
7.8
6.7
79.85
80.10
u/l
0.03
334
2868
164
1232
1.48
4.04
3.9
3.1
2.35
2.36
mmol/l
0.10
144
1107
175
1341
1.46
3.87
3.2
3.2
—
—
—
0
0
74
468
1.68
3.85
4.2
3.4
5.33
8.46
umol/l
1.77
62
395
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
21
83
2.59
3.84
7.1
4.5
0.27
0.34
u/ml
0.85
12
48
239
1962
1.40
3.54
7.4
6.1
12.04
11.27
umol/l
0.28
223
1856
49
288
1.77
3.31
2.7
3.3
4.54
4.65
pmol/l
0.38
44
254
87
595
1.55
3.29
3.3
2.4
2.41
2.43
mmol/l
0.77
72
513
419
3825
1.48
3.18
13.2
9.8
90.86
89.67
ml/min/173m2
0.46
350
3034
433
3984
1.50
3.11
5.1
4.6
1.81
2.13
mu/l
0.55
407
3733
23
106
2.22
3.07
1.7
2.5
—
—
—
0
0
13
46
2.87
2.94
1.2
1.4
—
—
—
0
0
63
411
1.61
2.92
13.7
8.2
104.59
104.37
mmol/l
0.14
63
411
336
2980
1.36
2.80
3.4
3.2
38.85
40.37
u/l
0.15
320
2839
120
905
1.42
2.79
2.8
2.9
2796.54
6826.89
umol/l
0.75
103
812
20
91
2.25
2.77
2.1
2.5
598.30
289.68
ug/l
0.64
20
83
9
24
3.80
2.68
1.7
1.8
21.44
32.54
umol/l
—
9
24
86
617
1.47
2.60
4.4
3.1
134.18
345.45
ng/l
0.80
60
393
45
281
1.66
2.50
7.8
6.3
1.06
1.11
mmol/l
0.04
34
207
72
505
1.49
2.44
8.9
7.0
1.15
1.10
mmol/l
0.57
66
478
342
3080
1.32
2.35
4.3
3.8
9.59
9.93
mm/h
0.22
316
2849
8
24
3.37
2.19
1.9
1.4
5.38
6.46
mmol/l
—
8
24
241
2089
1.28
2.13
4.1
2.9
88.01
83.96
ug/l
0.13
222
1949
476
4540
1.54
2.13
10.7
9.0
24.56
25.87
u/l
1.28
461
4394
9
31
2.94
2.08
2.1
1.6
—
—
—
0
0
22
119
1.89
2.00
1.1
1.5
229.79
220.06
u/ml
0.08
14
62
163
1354
1.30
1.98
2.0
1.8
91.49
97.47
pmol/l
1.00
88
692
29
173
1.72
1.94
1.3
1.3
—
—
—
0
0
129
1043
1.31
1.91
1.8
1.7
1.32
1.42
mmol/l
0.91
111
902
9
34
2.68
1.87
1.6
1.6
—
—
—
0
0
5
12
4.20
1.82
1.6
1.3
—
—
—
0
0
18
94
1.95
1.82
2.1
1.6
—
—
—
0
0
22
124
1.81
1.78
1.1
1.5
—
—
—
0
0
18
95
1.93
1.77
1.1
1.1
6.74
1.63
u/ml
—
7
41
17
88
1.96
1.76
4.5
2.0
—
—
—
0
0
74
558
1.38
1.73
5.1
4.5
0.81
0.82
mmol/l
0.09
67
529
152
1272
1.27
1.72
2.8
3.1
53.26
34.18
ng/l
0.32
85
725
23
135
1.74
1.65
1.3
1.1
—
—
—
0
0
10
41
2.47
1.65
1.1
1.6
2.05
1.28
promille
—
5
32
23
136
1.72
1.61
1.3
1.1
—
—
—
0
0
22
129
1.74
1.59
2.6
1.7
2.04
5.32
iu/l
—
9
44
6
20
3.02
1.58
1.0
1.2
1985.50
1628.45
miu/ml
—
6
20
125
1031
1.28
1.58
2.4
2.1
176.78
247.80
u/l
0.50
119
978
26
161
1.65
1.55
4.1
6.5
0.60
0.64
%
0.26
26
161
14
71
2.00
1.55
1.9
1.7
—
—
—
0
0
14
71
2.00
1.55
1.9
1.7
—
—
—
0
0
52
377
1.42
1.54
2.8
2.5
24.91
29.20
u/l
1.74
46
314
17
93
1.86
1.53
1.2
1.5
—
—
—
0
0
10
45
2.25
1.47
1.1
1.3
—
90.00
—
0
6
10
45
2.25
1.47
2.7
1.6
—
—
—
0
0
13
66
1.99
1.44
2.3
1.7
—
—
—
0
0
5
16
3.14
1.44
2.0
1.3
—
—
—
0
0
370
3465
1.23
1.37
3.4
3.6
—
—
—
0
0
5
17
2.96
1.36
4.4
3.1
64.20
139.46
ug/l
—
5
17
5
17
2.96
1.36
1.0
1.1
—
—
—
0
0
16
90
1.80
1.34
2.2
1.7
—
—
—
0
0
52
388
1.38
1.33
1.2
1.2
90.37
173.35
iu/ml
1.20
13
158
14
76
1.87
1.31
1.4
1.3
—
—
—
0
0
14
76
1.87
1.31
1.4
1.3
—
—
—
0
0
13
69
1.91
1.29
4.6
2.4
5.28
4.94
kpa
1.08
13
69
12
62
1.96
1.28
1.6
2.7
18.10
15.84
%
—
7
34
11
55
2.02
1.28
1.6
1.6
—
—
—
0
0
12
216
0.55
1.27
1.3
1.9
—
—
—
0
0
9
45
2.02
1.24
1.7
1.4
—
—
—
0
0
8
37
2.18
1.22
1.3
1.3
—
—
—
0
0
8
37
2.18
1.22
1.3
1.3
—
—
—
0
0
8
38
2.12
1.19
1.3
1.3
—
—
—
0
0
8
38
2.12
1.19
1.3
1.3
—
—
—
0
0
8
38
2.12
1.19
1.3
1.3
—
—
—
0
0
191
1698
1.20
1.18
3.0
2.4
73.93
73.24
nmol/l
0.14
178
1555
10
50
2.02
1.17
2.2
1.5
—
—
—
0
0
426
4075
1.24
1.16
4.2
4.2
2.88
2.84
mmol/l
0.32
394
3832
67
532
1.30
1.15
1.8
1.7
1186.17
1178.42
nmol/l
0.02
48
412
5
20
2.51
1.15
1.0
1.6
—
—
—
0
0
5
20
2.51
1.15
1.0
1.6
—
—
—
0
0
45
337
1.37
1.14
20.8
9.9
1.41
1.01
mmol/l
0.19
37
278
422
4035
1.24
1.14
3.9
3.8
4.72
4.73
mmol/l
0.08
392
3819
420
4014
1.24
1.13
3.8
3.8
1.47
1.48
mmol/l
0.21
393
3781
12
66
1.84
1.09
2.2
1.5
—
—
—
0
0
407
3885
1.21
1.07
3.3
3.5
1.25
1.26
mmol/l
0.16
379
3649
10
52
1.94
1.06
2.3
1.5
—
—
—
0
0
14
82
1.73
1.06
3.4
2.6
—
—
—
0
0
33
238
1.41
1.05
1.7
2.2
2.71
6.48
ug/l
2.82
26
213
7
34
2.07
1.03
1.0
1.7
—
—
—
0
0
7
34
2.07
1.03
1.0
1.7
—
—
—
0
0
7
34
2.07
1.03
1.0
1.7
—
—
—
0
0
9
47
1.93
1.02
1.8
1.6
—
—
—
0
0
137
1196
1.20
1.02
2.2
2.6
54.26
55.51
u/l
0.17
117
1116
378
3590
1.19
1.02
4.5
4.8
37.61
38.60
mmol/mol
1.54
356
3396
75
616
1.25
1.00
1.6
1.8
1.31
1.40
%
0.61
66
563
48
372
1.32
1.00
2.1
1.8
—
—
—
0
0
5
23
2.18
0.98
2.2
1.4
—
—
—
0
0
31
226
1.40
0.95
1.5
1.7
—
—
—
0
0
7
37
1.90
0.94
2.0
1.4
—
—
—
0
0
35
261
1.37
0.94
3.3
3.6
1.23
1.23
mmol/l
0.54
28
227
407
3901
1.20
0.94
3.7
3.7
5.72
5.75
mmol/l
0.14
378
3621
9
52
1.74
0.92
2.3
1.7
—
—
—
0
0
9
52
1.74
0.92
2.3
1.7
—
—
—
0
0
51
404
1.29
0.92
6.5
5.7
—
—
—
0
0
222
2039
1.15
0.87
4.3
4.6
0.00
0.00
estimate
0.50
34
416
10
57
1.77
0.84
2.3
2.7
2.66
12.69
u/ml
—
10
57
24
172
1.41
0.82
1.5
1.6
—
—
—
0
0
8
48
1.68
0.79
1.0
1.1
—
—
—
0
0
38
298
1.30
0.76
1.6
1.3
—
—
—
0
0
54
443
1.24
0.76
2.0
2.7
0.58
0.72
ug/l
1.16
30
269
52
425
1.25
0.75
2.4
2.0
379.20
377.57
nmol/l
0.02
45
398
20
141
1.44
0.75
1.2
1.1
—
—
—
0
0
11
172
0.63
0.75
2.1
1.7
—
—
—
0
0
59
491
1.23
0.73
1.7
1.6
—
—
—
0
0
5
25
2.01
0.73
2.0
1.8
0.12
0.14
nmol/l
—
5
19
5
25
2.01
0.73
2.4
1.4
—
—
—
0
0
7
39
1.81
0.72
1.1
1.1
—
—
—
0
0
19
134
1.43
0.72
1.4
1.3
—
—
—
0
0
11
68
1.63
0.72
1.2
1.2
—
—
—
0
0
36
283
1.29
0.72
19.2
10.5
121.75
121.97
g/l
0.02
36
276
38
301
1.28
0.71
1.3
1.5
23.15
22.75
iu/l
0.03
30
247
45
365
1.25
0.70
2.2
1.7
—
—
—
0
0
7
41
1.72
0.70
1.0
1.2
—
—
—
0
0
13
85
1.54
0.69
7.9
4.2
39.31
37.56
umol/l
0.15
13
80
30
231
1.32
0.69
1.4
1.5
—
—
—
0
0
86
748
1.18
0.68
1.2
1.3
15.94
28.69
iu/ml
1.63
22
235
28
214
1.33
0.68
1.5
1.4
—
—
—
0
0
28
214
1.33
0.68
1.5
1.4
—
—
—
0
0
5
94
0.53
0.67
1.0
2.0
1.54
0.73
nmol/l
—
5
77
7
43
1.64
0.67
2.1
1.9
—
—
—
0
0
28
215
1.32
0.66
1.5
1.4
—
—
—
0
0
28
215
1.32
0.66
1.5
1.4
—
—
—
0
0
88
770
1.17
0.65
3.7
4.2
1.57
2.32
ug/l
1.07
75
702
15
103
1.47
0.65
2.4
2.2
10.81
10.35
mg/l
0.08
15
94
10
154
0.64
0.65
1.3
1.5
—
—
—
0
0
39
315
1.26
0.64
1.1
1.0
—
—
—
0
0
15
104
1.46
0.63
1.9
1.4
267.56
298.68
ug/g
—
9
59
10
63
1.60
0.62
1.5
1.4
—
—
—
0
0
88
776
1.16
0.60
1.7
1.4
22.71
21.21
nmol/l
0.36
80
676
0
23
0.00
0.58
0.0
3.2
—
—
—
0
0
220
2063
1.11
0.58
3.1
3.3
0.00
0.01
estimate
0.50
33
401
18
132
1.38
0.57
1.4
1.8
—
234.29
—
0
7
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
8
55
1.46
0.56
1.0
1.1
—
—
—
0
0
13
90
1.46
0.56
1.1
1.2
—
—
—
0
0
10
65
1.55
0.56
1.8
1.5
8.32
7.13
mmol/l
—
10
56
9
60
1.51
0.54
1.2
1.1
—
—
—
0
0
62
537
1.18
0.54
2.1
1.8
—
—
—
0
0
15
204
0.73
0.54
1.2
1.6
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
339.17
203.21
mg/l
—
6
33
6
39
1.54
0.53
1.5
1.1
—
—
—
0
0
29
233
1.26
0.52
2.0
1.7
—
—
—
0
0
9
64
1.41
0.51
2.4
1.4
—
—
—
0
0
147
1588
0.90
0.51
3.3
3.3
—
—
—
0
0
7
48
1.46
0.47
1.9
1.4
—
—
—
0
0
126
1161
1.11
0.46
3.7
3.2
8.16
8.07
mmol/l
0.06
110
1015
100
910
1.12
0.45
2.3
2.2
—
—
—
0
0
5
31
1.62
0.43
1.2
1.1
—
—
—
0
0
5
31
1.62
0.43
1.2
1.2
—
—
—
0
0
5
32
1.57
0.42
1.4
1.2
49.86
43.84
nmol/l
—
5
23
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
17
216
0.78
0.41
1.8
1.8
3.54
3.54
mg/l
0.00
12
160
86
781
1.12
0.41
3.9
3.2
1291.35
897.28
ng/l
0.63
68
644
0
17
0.00
0.40
0.0
1.2
—
8.31
—
0
17
214
2036
1.09
0.40
3.2
3.3
0.00
0.00
estimate
0.50
35
431
21
169
1.25
0.39
1.4
1.7
—
—
—
0
0
12
90
1.34
0.36
1.4
1.4
—
—
—
0
0
10
134
0.74
0.35
1.9
1.7
—
—
—
0
0
7
55
1.28
0.30
1.9
1.1
—
—
—
0
0
7
55
1.28
0.30
2.3
1.7
—
—
—
0
0
36
317
1.15
0.29
2.7
2.3
25.56
17.89
au/ml
—
5
15
5
73
0.68
0.26
7.0
5.5
357.00
362.56
umol/l
—
5
66
25
218
1.15
0.23
1.4
1.4
—
—
—
0
0
77
720
1.08
0.23
1.7
1.6
444.67
24038891.99
pmol/l
0.80
61
624
88
829
1.07
0.22
2.2
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
402.00
—
0
6
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
1.22
—
0
12
33
297
1.12
0.21
2.2
4.0
3.18
23.68
ug/l
0.80
23
243
60
558
1.09
0.21
2.4
1.9
—
—
—
0
0
6
49
1.23
0.20
4.8
1.4
—
—
—
0
0
19
218
0.87
0.20
1.2
1.3
308.99
253.55
miu/ml
—
8
113
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
66
621
1.07
0.18
2.6
3.9
21.88
21.61
%
0.05
25
274
118
1228
0.95
0.17
1.4
1.4
1.20
2.10
u/ml
0.73
33
319
89
932
0.95
0.16
3.7
3.3
1.02
1.02
kg/l
—
7
126
25
274
0.91
0.14
1.5
1.4
—
—
—
0
0
10
84
1.19
0.14
1.2
1.4
—
—
—
0
0
12
138
0.87
0.13
2.0
1.9
—
—
—
0
0
19
171
1.12
0.12
1.7
1.5
—
—
—
0
0
70
731
0.95
0.12
1.3
1.3
17.87
8.65
u/ml
0.43
27
288
13
114
1.14
0.12
2.4
3.4
82.77
1447.74
u/ml
0.57
13
96
127
1235
1.04
0.11
1.6
1.7
—
—
—
0
0
10
86
1.17
0.11
1.2
1.0
—
10.83
—
0
6
10
86
1.17
0.11
1.1
1.1
—
—
—
0
0
5
45
1.11
0.10
4.0
3.4
—
—
—
0
0
47
449
1.05
0.09
2.4
1.8
—
—
—
0
0
6
54
1.11
0.09
1.2
1.2
—
—
—
0
0
7
65
1.08
0.08
3.6
2.8
17.71
28.78
u/ml
—
7
65
39
406
0.96
0.06
1.5
1.5
—
—
—
0
0
16
149
1.08
0.05
1.1
2.0
—
—
—
0
0
19
201
0.94
0.04
1.2
1.4
—
—
—
0
0
11
101
1.09
0.04
2.4
1.9
—
—
—
0
0
12
111
1.08
0.04
2.3
1.5
—
—
—
0
0
42
430
0.97
0.02
4.4
3.7
32.94
31.59
%
0.33
31
307
108
1092
0.99
0.02
3.8
3.4
0.00
0.00
estimate
0.80
34
408
96
970
0.99
0.02
4.6
3.9
4.78
11.07
mg/mmol
2.07
66
638
89
884
1.01
0.00
1.4
1.5
—
—
—
0
0
18
183
0.98
0.00
13.0
9.5
26.80
24.58
mmol/l
0.81
18
172
13
128
1.02
0.00
1.2
1.3
—
—
—
0
0
32
317
1.01
0.00
2.2
2.2
230.40
3498.47
u/l
—
10
128
0
6
0.00
-0.00
0.0
1.8
—
1.36
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
2.95
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
2.67
—
0
6
0
6
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
53
0.94
-0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.2
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
2.18
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
1.24
—
0
6
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
54
0.93
-0.00
1.2
1.4
—
—
—
0
0
5
53
0.94
-0.00
1.2
1.4
—
—
—
0
0
8
84
0.95
-0.00
5.9
4.0
57.25
55.79
%
—
8
84
5
54
0.93
-0.00
1.2
1.4
—
—
—
0
0
5
54
0.93
-0.00
1.2
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
2.21
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
6.08
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM | 1.126 [0.85, 1.5] | 0.416 |
| Birth year | 0.994 [0.99, 1.0] | 0.189 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 1690 females with Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM | 1.198 [0.87, 1.65] | 0.266 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 1287 males with Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM died.
Mortality risk
Mortality risk for people of age
years, who have Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.135% | 0.224% |
| 5 | 0.647% | 1.384% |
| 10 | 1.645% | 3.654% |
| 15 | 3.268% | 6.451% |
| 20 | 5.809% | 10.974% |
Relationships between endpoints
↥Index endpoint: Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM – Other congenital malformations of peripheral vascular system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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