No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
65 |
4. Check minimum number of eventsNone |
65 |
5. Include endpointsNone |
65 |
6. Filter based on genotype QC (FinnGen only) |
65 |
Control definitions (FinnGen only)
- Control exclude
- G6_NERPLEX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G54
- Name in latin
- Amyotrophia neuralgica
Similar endpoints
↥List of similar endpoints to
Neuralgic amyotrophy
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 398 | 163 | 231 |
| Only index persons | 371 | 152 | 219 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.00 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 52.03 | 50.89 | 52.84 |
| Only index persons | 51.07 | 50.12 | 51.73 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 65 | 25 | 40 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | 60.58 | 58.50 | 61.89 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 60
- Matched controls
- 599
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G54.5
ICD-10 Finland
Neuralgic amyotrophy
+∞
83.3
59
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
16.1
8.9
14
11
TAB00
NOMESCO Finland
Lumbar puncture
18.0
8.7
13
9
R4120
NOMESCO Finland
Occupational therapy
12.4
7.5
13
13
N03AX16
ATC
pregabalin; oral
5.0
6.8
24
70
G56.0
ICD-10 Finland
Carpal tunnel syndrome
30.2
6.4
8
*
G54.9
ICD-10 Finland
Nerve root and plexus disorder, unspecified
+∞
6.4
6
*
Mortality – FinRegistry
↥Association
Association between endpoint G6_NEURAMYO and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have G6_NEURAMYO.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: G6_NEURAMYO – Neuralgic amyotrophy
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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