Melanocytic naevi of eyelid, including canthus

CD2_BENIGN_MELANOCYTIC_EYELID

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.1&
  • Hospital discharge: ICD-9 2161A
  • Cause of death: ICD-10 D22.1&
  • Cause of death: ICD-9 2161A

2 out of 7 registries used, show all original rules.

346

4. Check minimum number of events

None

346

5. Include endpoints

None

346

6. Filter based on genotype QC (FinnGen only)

337

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus palpebrae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2724 1781 930
Only index persons 2569 1697 872
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.05 0.06 0.03
Median age at first event (years)
Whole population 53.01 52.48 53.88
Only index persons 52.34 51.73 53.51

-FinnGen-

Key figures

All Female Male
Number of individuals 337 228 109
Unadjusted period prevalence (%) 0.07 0.08 0.05
Median age at first event (years) 53.79 50.18 61.32

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
346
Matched controls
3460
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.1
ICD-10 Finland
Melanocytic naevi of eyelid, including canthus
8837.7
307.7
331
*
CBB30
NOMESCO Finland
Excision of lesion of eyelid
41.4
172.6
111
39
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
7.3
52.1
90
158
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
9.5
34.2
43
51
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
105.9
18.8
20
*
2161A
ICD-9 Finland
Benign neoplasm of skin, Eyelid, including canthus[SILMÄLUOMEN BEN KASVAIN, NAEVUS PIGMENTOSUS]
+∞
15.7
15
*
CBA10
NOMESCO Finland
Biopsy of eyelid
15.4
11.9
19
13
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
8.1
10.6
23
30
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.4
10.1
38
121
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.8
8.6
47
186
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.4
8.1
30
94
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
3.3
7.6
29
93
L82
ICD-10 Finland
Seborrhoeic keratosis
2.1
6.9
76
410
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.0
6.2
73
404

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
164
1205
1.69
5.35
2.3
2.1
—
—
—
0
0
184
1456
1.56
4.05
5.3
5.5
1.91
1.94
e9/l
0.12
174
1314
185
1476
1.54
3.85
5.5
5.7
0.20
0.19
e9/l
0.33
170
1311
178
1424
1.51
3.56
5.4
5.4
0.56
0.56
e9/l
0.12
163
1250
169
1346
1.50
3.41
5.5
6.0
—
—
—
0
0
177
1428
1.49
3.32
5.4
5.4
0.04
0.04
e9/l
0.72
162
1252
120
904
1.50
3.10
3.1
2.5
58.83
62.38
u/l
0.25
113
844
248
2177
1.49
2.82
4.2
4.0
11.59
11.48
mm/h
0.04
233
2003
167
1363
1.44
2.79
5.8
5.7
29.13
27.98
%
0.76
159
1287
163
1328
1.43
2.73
5.7
5.5
2.79
2.77
%
0.04
154
1245
163
1336
1.42
2.61
5.9
5.8
8.45
8.44
%
0.01
155
1254
157
1286
1.40
2.49
5.9
5.5
0.63
0.67
%
0.33
149
1198
163
1349
1.39
2.41
5.6
5.4
56.85
57.46
%
0.25
155
1273
252
2259
1.43
2.24
4.5
4.1
14.84
14.69
pmol/l
0.41
233
2053
5
9
5.62
2.22
1.2
1.1
—
—
—
0
0
291
2690
1.51
2.12
5.3
4.8
1.87
2.33
mu/l
0.50
273
2463
34
209
1.70
2.07
1.4
1.4
—
—
—
0
0
6
15
4.05
2.04
5.8
6.9
—
—
—
0
0
50
343
1.54
1.97
1.3
1.4
—
—
—
0
0
192
1668
1.34
1.94
8.8
8.9
3.89
4.07
e9/l
0.56
172
1464
305
2863
1.55
1.89
4.7
4.4
4.66
4.72
mmol/l
0.46
285
2667
35
223
1.63
1.88
1.3
1.1
—
—
—
0
0
118
957
1.35
1.88
3.3
3.3
2.37
2.36
mmol/l
0.67
101
853
6
17
3.57
1.84
2.0
1.6
—
—
—
0
0
245
2221
1.35
1.78
7.5
7.4
77.18
77.50
u/l
0.04
233
2079
313
2963
1.59
1.77
15.4
15.1
3.95
3.96
mmol/l
0.45
308
2887
71
534
1.41
1.77
1.4
1.3
12.20
8.75
u/ml
0.13
22
213
312
2952
1.58
1.77
15.1
15.0
139.97
139.72
mmol/l
1.14
307
2880
72
544
1.41
1.75
1.4
1.3
24.74
38.32
iu/ml
0.77
32
183
41
277
1.54
1.74
1.3
1.4
—
—
—
0
0
13
61
2.18
1.74
4.5
4.4
19.22
29.05
mg/l
0.60
13
39
92
727
1.36
1.71
2.2
2.6
330.73
6963.52
umol/l
3.40
79
629
52
372
1.47
1.69
1.3
1.2
—
—
—
0
0
176
1537
1.30
1.60
5.5
6.0
10.45
10.62
umol/l
0.10
167
1460
221
1990
1.31
1.59
3.8
3.7
—
—
—
0
0
21
122
1.77
1.58
1.2
1.2
—
—
—
0
0
308
2919
1.50
1.58
5.3
4.9
2.79
2.79
mmol/l
0.03
286
2704
307
2910
1.49
1.54
13.5
13.1
23.92
22.22
mg/l
0.29
248
2281
5
15
3.37
1.53
1.2
1.5
—
—
—
0
0
139
1184
1.29
1.51
4.6
4.6
36.70
36.06
g/l
0.75
134
1115
146
1263
1.27
1.38
14.3
12.3
1.37
1.24
inr
0.65
40
377
267
2488
1.32
1.37
19.3
17.3
332.23
331.95
g/l
0.21
267
2477
32
219
1.51
1.31
1.6
1.4
—
—
—
0
0
8
34
2.38
1.30
22.9
8.9
7.38
6.74
mmol/l
—
8
28
300
2852
1.39
1.28
4.6
4.3
1.44
1.51
mmol/l
2.61
281
2638
291
2756
1.35
1.25
4.2
3.9
1.26
1.26
mmol/l
0.01
270
2537
79
640
1.30
1.23
3.9
3.8
1.02
1.02
kg/l
0.09
13
86
11
198
0.54
1.20
1.7
2.8
4.32
4.38
kpa
0.03
11
191
282
2664
1.32
1.19
5.9
5.5
39.25
39.42
mmol/mol
0.11
265
2490
14
234
0.58
1.18
3.1
3.5
5.81
5.76
kpa
0.07
14
226
156
1379
1.24
1.18
5.8
6.4
1.21
1.22
mmol/l
0.45
134
1181
155
1370
1.24
1.17
2.5
2.5
—
—
—
0
0
53
409
1.35
1.16
1.5
1.4
1192.00
520.48
titre
—
10
84
182
1643
1.23
1.11
5.3
4.7
6.45
6.60
mmol/l
0.56
168
1510
5
21
2.40
1.09
1.0
1.3
—
—
—
0
0
7
32
2.21
1.08
1.4
1.2
—
—
—
0
0
7
33
2.14
1.06
1.1
1.1
—
—
—
0
0
7
33
2.14
1.06
1.0
1.6
—
—
—
0
0
11
60
1.86
1.04
2.6
1.8
118.17
128.82
g/l
—
6
38
5
22
2.29
1.03
1.8
1.1
—
—
—
0
0
16
99
1.65
1.02
3.1
1.5
313.69
299.09
mu/l
0.08
16
91
295
2820
1.31
1.01
4.5
4.4
5.93
5.87
mmol/l
0.32
275
2588
63
510
1.29
1.00
3.6
2.8
2.43
2.45
mmol/l
1.14
54
450
0
29
0.00
0.98
0.0
1.5
—
275.95
—
0
19
7
36
1.96
0.97
3.1
1.9
13.29
13.18
%
—
7
36
127
1117
1.22
0.97
1.9
1.9
96.92
97.26
pmol/l
0.02
53
568
8
142
0.55
0.95
1.8
3.9
—
—
—
0
0
318
3081
1.40
0.92
11.2
10.2
25.52
25.07
u/l
0.10
307
2973
313
3026
1.36
0.91
12.6
12.3
—
—
—
0
0
6
29
2.09
0.89
1.2
1.2
—
—
—
0
0
77
648
1.24
0.89
3.4
3.6
—
—
—
0
0
6
30
2.02
0.87
1.0
1.1
—
—
—
0
0
8
44
1.84
0.86
1.3
1.9
—
—
—
0
0
136
1216
1.20
0.86
2.1
2.2
74.03
76.94
nmol/l
0.67
123
1074
6
31
1.95
0.85
3.0
3.8
—
—
—
0
0
96
832
1.21
0.84
2.0
2.1
197.22
150.03
u/l
0.35
88
789
78
662
1.23
0.84
1.3
1.2
2.53
1.35
u/ml
0.27
23
190
207
1924
1.19
0.83
3.0
3.1
40.14
43.66
u/l
0.29
197
1802
91
786
1.21
0.83
3.9
3.6
0.00
0.00
estimate
0.50
27
257
33
251
1.35
0.82
1.5
1.4
—
—
—
0
0
6
32
1.89
0.82
2.2
3.0
0.68
0.74
nmol/l
—
6
25
78
669
1.21
0.76
2.0
2.0
2.29
3.03
mg/l
3.52
73
571
7
38
1.86
0.74
1.0
1.6
—
—
—
0
0
7
38
1.86
0.74
1.9
3.1
—
—
—
0
0
14
92
1.54
0.73
1.9
2.8
0.14
0.24
g/l
—
8
32
70
813
0.83
0.72
1.5
1.4
—
—
—
0
0
76
655
1.21
0.71
1.5
1.5
21.78
21.41
nmol/l
0.07
67
541
138
1253
1.17
0.71
5.3
5.8
1.22
1.22
mmol/l
0.05
127
1141
328
3210
1.42
0.71
21.0
19.6
40.31
40.17
%
0.17
299
3019
9
59
1.54
0.69
1.9
1.6
—
—
—
0
0
5
27
1.86
0.68
1.0
1.2
—
—
—
0
0
7
43
1.64
0.67
1.3
1.5
—
—
—
0
0
328
3213
1.40
0.67
21.1
19.6
4.49
4.48
e12/l
0.11
322
3129
328
3213
1.40
0.67
21.1
19.6
6.70
6.68
e9/l
0.07
321
3128
83
726
1.19
0.66
8.9
6.7
—
—
—
0
0
126
1143
1.16
0.65
3.4
3.4
5.50
5.89
ph
—
6
89
17
121
1.43
0.63
1.2
1.3
—
2.79
—
0
10
71
812
0.84
0.62
3.5
3.8
—
—
—
0
0
9
140
0.63
0.61
1.7
2.5
1.34
1.23
%
—
9
140
5
30
1.68
0.61
1.2
1.1
—
—
—
0
0
201
1894
1.15
0.59
4.5
4.3
1614.50
224.08
e6/l
0.65
12
36
0
22
0.00
0.59
0.0
1.6
—
69.73
—
0
22
6
37
1.63
0.56
2.0
3.3
—
—
—
0
0
47
552
0.83
0.55
2.1
2.7
536.98
545.28
mosm/kgh2o
0.11
42
472
327
3211
1.33
0.55
21.2
19.6
254.87
252.88
e9/l
0.20
322
3139
40
333
1.23
0.54
1.5
1.4
—
—
—
0
0
11
74
1.50
0.54
1.0
1.1
—
—
—
0
0
9
135
0.66
0.52
1.7
2.5
0.58
0.68
%
—
9
135
56
484
1.19
0.52
1.5
1.7
1274.60
1193.52
nmol/l
0.25
43
358
6
40
1.51
0.52
1.2
1.9
69.10
61.13
%
—
6
40
6
40
1.51
0.52
1.0
1.1
—
—
—
0
0
27
216
1.27
0.51
1.1
1.2
203.55
161.39
iu/ml
0.21
19
91
26
207
1.28
0.51
2.0
2.4
75.85
71.95
e9/l
0.11
19
157
211
2007
1.13
0.51
4.4
4.2
—
—
—
0
0
152
1420
1.13
0.49
3.5
3.5
0.00
0.00
estimate
-0.00
30
286
136
1264
1.13
0.47
8.1
8.6
0.00
0.00
e9/l
0.65
123
1033
7
48
1.47
0.47
1.0
1.1
—
—
—
0
0
34
404
0.82
0.46
2.3
2.9
1.03
0.72
ug/l
0.34
22
261
47
406
1.18
0.45
1.3
1.2
—
—
—
0
0
17
130
1.32
0.45
15.7
13.2
—
—
—
0
0
11
78
1.42
0.43
1.1
1.1
—
58.57
—
0
7
80
723
1.14
0.43
3.7
3.8
—
—
—
0
0
6
93
0.64
0.43
1.2
1.3
—
—
—
0
0
8
56
1.44
0.43
1.1
1.3
—
—
—
0
0
8
57
1.41
0.42
1.0
1.2
—
—
—
0
0
114
1057
1.12
0.41
3.2
3.6
24.68
33.94
ng/l
0.92
61
720
8
59
1.36
0.41
1.5
1.2
—
—
—
0
0
48
420
1.17
0.40
1.5
2.0
—
—
—
0
0
0
19
0.00
0.39
0.0
8.9
—
0.62
—
0
19
76
691
1.13
0.38
4.7
4.9
2.63
2.52
ug/l
0.04
68
609
13
98
1.34
0.38
1.4
1.4
110.23
231.03
miu/ml
—
7
50
15
116
1.31
0.37
1.2
1.9
—
—
—
0
0
151
1428
1.10
0.37
4.5
4.8
0.00
0.00
estimate
-0.00
29
267
136
1280
1.10
0.37
2.9
2.7
167.96
104.40
ug/l
0.38
131
1174
35
301
1.18
0.36
3.6
4.0
3.78
21.22
ug/l
0.65
28
246
5
76
0.65
0.36
1.2
1.2
12.82
11.66
u/l
—
5
62
92
851
1.11
0.35
2.5
3.0
—
—
—
0
0
52
465
1.14
0.34
1.5
1.6
—
—
—
0
0
6
45
1.34
0.34
1.0
1.4
37.42
30.29
u/l
—
6
37
152
1444
1.09
0.33
3.5
3.6
0.00
0.00
estimate
-0.00
28
260
36
314
1.16
0.33
1.6
1.6
—
—
—
0
0
6
47
1.28
0.32
2.0
1.5
—
—
—
0
0
7
52
1.35
0.31
1.9
1.2
—
—
—
0
0
24
203
1.20
0.31
1.2
1.2
—
—
—
0
0
60
546
1.12
0.30
1.6
1.7
—
—
—
0
0
12
93
1.30
0.30
1.3
2.2
39.40
37.54
g/l
0.68
12
82
99
1055
0.91
0.30
3.1
2.9
—
—
—
0
0
41
366
1.14
0.28
2.3
2.3
112.81
123.76
ug/g
0.15
32
297
39
436
0.88
0.28
2.4
2.7
4.64
2.90
e6/l
0.38
22
227
20
168
1.20
0.28
10.8
7.3
—
—
—
0
0
20
236
0.84
0.27
3.6
3.3
—
—
—
0
0
27
309
0.86
0.26
1.3
1.4
—
—
—
0
0
64
590
1.10
0.26
2.4
2.4
6.62
6.45
e6/l
0.03
57
531
15
123
1.23
0.26
1.1
1.0
—
—
—
0
0
41
371
1.12
0.24
1.8
2.2
23.73
22.42
%
0.23
33
316
71
760
0.92
0.24
2.5
2.7
—
—
—
0
0
15
179
0.83
0.23
1.1
1.2
—
—
—
0
0
56
517
1.10
0.23
3.9
3.4
208.29
356.95
ng/l
0.39
41
387
37
334
1.12
0.22
1.6
1.7
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
19
163
1.18
0.22
1.8
1.7
—
—
—
0
0
20
230
0.86
0.21
4.2
6.5
1.60
1.32
mmol/l
0.56
20
225
0
11
0.00
0.21
0.0
1.1
—
58.35
—
0
6
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
8
105
0.76
0.21
1.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.6
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
7.53
—
0
13
6
48
1.25
0.20
3.2
2.1
—
—
—
0
0
25
281
0.88
0.20
1.5
1.6
—
—
—
0
0
76
805
0.93
0.20
3.2
3.1
—
—
—
0
0
18
207
0.86
0.19
3.8
3.9
0.33
0.52
%
—
6
69
6
51
1.18
0.19
1.2
2.9
—
—
—
0
0
7
61
1.15
0.17
2.9
2.1
8.94
7.89
kpa
—
7
61
90
859
1.06
0.17
3.4
3.0
6.84
7.45
mmol/l
0.67
81
716
7
63
1.11
0.17
1.7
1.7
4.76
4.81
mmol/24h
—
7
53
5
68
0.73
0.17
1.4
2.2
—
—
—
0
0
18
159
1.14
0.15
3.4
2.5
0.06
0.17
e6/l
0.80
18
154
9
81
1.11
0.15
1.1
1.3
—
—
—
0
0
84
806
1.06
0.14
3.6
3.1
105.71
229.88
mg/l
0.52
53
506
31
335
0.92
0.13
1.3
1.3
—
—
—
0
0
75
783
0.95
0.13
2.5
2.8
0.60
0.58
e6/l
0.01
56
574
104
1005
1.05
0.13
3.4
3.3
126.27
64.27
e6/l
0.40
73
705
32
299
1.08
0.11
9.2
8.6
2.02
1.32
mmol/l
0.57
26
246
82
793
1.04
0.10
1.8
1.7
1.35
1.35
mmol/l
0.03
70
666
5
44
1.14
0.10
1.0
2.1
9.00
4.53
umol/l
—
5
31
5
48
1.04
0.09
2.2
3.4
4.20
4.59
e9/l
—
5
48
5
48
1.04
0.09
2.8
1.3
—
—
—
0
0
6
55
1.09
0.09
1.7
1.3
—
—
—
0
0
63
608
1.04
0.08
1.5
1.4
2.47
2.44
g/l
0.03
40
382
59
569
1.04
0.08
1.4
1.7
423.14
10504646.09
pmol/l
0.50
51
476
5
65
0.77
0.08
2.0
2.5
7.42
7.43
ph
—
5
54
31
293
1.06
0.08
1.8
1.3
—
—
—
0
0
10
88
1.14
0.08
1.1
1.3
—
—
—
0
0
7
68
1.03
0.08
3.1
2.2
23.87
24.94
mmol/l
—
7
68
6
72
0.83
0.07
1.2
1.3
—
—
—
0
0
20
186
1.08
0.07
1.5
2.3
—
—
—
0
0
19
204
0.93
0.07
3.4
4.2
0.00
0.02
%
—
6
60
9
86
1.05
0.07
1.7
2.3
14.03
11.29
mg/l
—
9
78
10
89
1.13
0.07
1.1
1.3
—
—
—
0
0
10
89
1.13
0.07
1.1
1.3
—
—
—
0
0
10
89
1.13
0.07
1.1
1.3
—
—
—
0
0
64
659
0.96
0.07
1.6
1.6
1.11
1.13
mg/l
0.02
50
512
22
234
0.94
0.06
3.8
4.0
0.56
0.85
%
—
9
88
91
930
0.97
0.06
2.3
2.2
—
—
—
0
0
10
90
1.11
0.05
1.1
1.2
—
—
—
0
0
16
149
1.08
0.05
1.1
1.1
—
6.20
—
0
5
11
100
1.10
0.05
1.5
1.5
—
—
—
0
0
25
238
1.05
0.05
3.0
3.3
—
—
—
0
0
27
258
1.05
0.05
3.7
3.9
—
—
—
0
0
88
864
1.02
0.05
2.8
2.9
132.38
126.97
e6/l
0.01
69
655
24
251
0.95
0.04
2.0
2.1
0.22
0.22
g/l
0.09
24
239
18
190
0.94
0.04
1.6
2.5
—
—
—
0
0
12
111
1.08
0.04
1.8
4.2
—
—
—
0
0
17
161
1.06
0.03
2.4
2.0
14.35
13.08
nmol/l
0.28
17
151
11
102
1.08
0.03
5.3
10.2
—
—
—
0
0
13
138
0.94
0.02
2.7
2.4
—
—
—
0
0
85
860
0.98
0.02
3.4
3.8
7.39
7.40
ph
0.51
12
152
13
123
1.06
0.01
1.0
1.1
—
—
—
0
0
86
852
1.01
0.01
4.1
3.7
15.24
11.66
mg/mmol
0.28
54
514
21
216
0.97
0.00
4.0
4.1
0.00
0.13
%
—
8
70
12
118
1.02
0.00
3.7
3.0
—
—
—
0
0
19
192
0.99
0.00
1.3
1.4
—
—
—
0
0
21
209
1.01
0.00
5.1
7.9
—
—
—
0
0
28
275
1.02
0.00
2.1
2.2
29.14
32.32
u/l
0.33
22
230
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
34.60
—
0
5
0
6
0.00
0.00
0.0
2.3
—
15.88
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
4.38
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.04
—
0
5
0
5
0.00
0.00
0.0
2.2
—
10948.80
—
0
5
0
5
0.00
0.00
0.0
1.0
—
9.08
—
0
5
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
51
0.98
-0.00
2.8
1.3
0.62
0.50
nmol/l
—
5
46
7
77
0.91
-0.00
3.3
2.2
1.47
1.53
mg/l
—
7
70
9
91
0.99
-0.00
1.2
2.9
—
—
—
0
0
5
59
0.85
-0.00
1.0
4.4
—
—
—
0
0
5
51
0.98
-0.00
2.6
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
1.21
—
0
7
12
120
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
83
0.96
-0.00
2.9
3.0
—
—
—
0
0
5
53
0.94
-0.00
1.4
1.5
—
—
—
0
0
5
49
1.02
-0.00
2.6
3.8
53.40
57.82
%
—
5
49
19
190
1.00
-0.00
5.2
2.9
27.43
36.21
u/ml
0.29
19
181
9
99
0.91
-0.00
1.2
2.1
21.00
21.99
s
—
9
92
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_EYELID and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_EYELID 1.0 [0.84, 1.19] 0.997
Birth year 0.992 [0.98, 1.0] 0.082

During the follow-up period (1.1.1998 — 31.12.2019), 204 out of 1551 females with CD2_BENIGN_MELANOCYTIC_EYELID died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_EYELID 0.878 [0.71, 1.08] 0.225
Birth year 0.99 [0.98, 1.0] 0.034

During the follow-up period (1.1.1998 — 31.12.2019), 131 out of 811 males with CD2_BENIGN_MELANOCYTIC_EYELID died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_EYELID.

N-year risk Females Males
1 0.089% 0.209%
5 0.526% 0.992%
10 1.281% 2.568%
15 2.448% 5.089%
20 4.458% 8.86%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_EYELID – Melanocytic naevi of eyelid, including canthus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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