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Benign neoplasm: Spinal meninges

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_MENINGES_SPINAL

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D32.1&
  • Hospital discharge: ICD-9 — 2254
  • Hospital discharge: ICD-8 — 2254
  • Cause of death: ICD-10 — D32.1&
  • Cause of death: ICD-9 — 2254
  • Cause of death: ICD-8 — 2254

2 out of 7 registries used, show all original rules.

350

4. Check minimum number of events

None

350

5. Include endpoints

None

350

6. Filter based on genotype QC (FinnGen only)

350

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D32
Name in latin
Neoplasma benignum meningum spinalium

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2153 1510 634
Only index persons 1841 1306 535
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.02
Only index persons 0.04 0.05 0.02
Median age at first event (years)
Whole population 62.54 63.92 59.41
Only index persons 61.91 63.16 58.86

-FinnGen-

Key figures

All Female Male
Number of individuals 350 248 102
Unadjusted period prevalence (%) 0.07 0.08 0.04
Median age at first event (years) 61.81 61.88 61.64

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
304
Matched controls
3039
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
+∞
323.0
284
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
2745.7
165.6
145
*
9530/0-C70.1
ICD-O-3
Meningioma, NOS, of spinal meninges
+∞
65.0
60
*
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
78.1
64.9
72
12
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
319.5
54.0
53
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
39.3
35.2
44
13
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
29.9
34.4
46
18
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
8.8
33.1
76
111
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
+∞
28.6
27
*
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
71.2
28.5
32
5
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
59.3
27.8
32
6
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
271.4
25.1
25
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
15.9
23.3
38
27
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
14.9
22.1
37
28
9560/0-C72.0
ICD-O-3
Schwannoma, NOS, of spinal cord
+∞
20.0
19
*
2254A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal meninges
+∞
20.0
19
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
71.0
17.9
20
*
D33.43
ICD-10 Finland
Spinal cord
+∞
17.9
17
*
G82.2
ICD-10 Finland
Paraplegia, unspecified
53.3
17.2
20
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
7.3
17.2
42
65
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
16.8
16
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.4
16.4
92
341
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
22.5
16.2
23
11
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
15.8
15
*
N03AX16
ATC
pregabalin; oral
3.0
15.4
115
516
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
14.7
14
*
2312
FHL
Extirpation or destruction
+∞
14.7
14
*
N03AX12
ATC
gabapentin; oral
3.3
14.1
82
308
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
18.7
14.0
21
12
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
13.6
123
613
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
146.3
13.6
14
*
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
73.0
12.7
14
*
N75
ICPC
Benign neoplasm nervous system
+∞
12.6
12
*
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
39.3
12.3
15
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
12.1
55
170
NA7FT
NOMESCO Finland
Labeling lesion in spinal area with X-ray guidance
124.5
11.5
12
*
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
45.1
11.0
13
*
M03BX01
ATC
baclofen; systemic
11.8
10.7
19
17
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.7
10.6
36
84
G992, D321
ICD-10 Finland
NA
+∞
10.5
10
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.8
10.1
44
131
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
56.9
9.7
11
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.6
8.8
25
48
R20.2
ICD-10 Finland
Paraesthesia of skin
3.9
8.8
36
101
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
92.5
8.5
9
*
9537/0-C70.1
ICD-O-3
Transitional meningioma of spinal meninges
+∞
8.4
8
*
D42.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal meninges
+∞
8.4
8
*
9531/0-C70.1
ICD-O-3
Meningothelial meningioma of spinal meninges
+∞
8.4
8
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
+∞
8.4
8
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
+∞
8.4
8
*
L28
ICPC
Limited function/disability (L)
2.5
8.2
68
312
M54.4
ICD-10 Finland
Lumbago with sciatica
2.6
7.6
59
258
AA1BD
NOMESCO Finland
Extensive CT of head and brain
7.4
7.6
17
24
XKD00
NOMESCO Finland
Uroflowmetry
2.6
7.6
57
247
N06AX21
ATC
duloxetine; oral
2.8
7.6
48
188
XKD06
NOMESCO Finland
Physiologic investigation of micturition
5.6
7.5
21
40
D33.46
ICD-10 Finland
Benign neurofibroma in the nerve root of the spinal cord
+∞
7.3
7
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
7.3
33
102
N18
ICPC
Paralysis/weakness
6.9
7.2
17
26
M48.0
ICD-10 Finland
Spinal stenosis
2.6
7.0
54
237
N02BE01
ATC
paracetamol; systemic, rectal
2.5
6.8
273
2361
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
41.0
6.8
8
*
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
41.0
6.8
8
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
12.6
6.6
11
9
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.9
6.6
17
30
G82.1
ICD-10 Finland
Spastic paraplegia
71.3
6.4
7
*
D32.04
ICD-10 Finland
Secondary or multiple benign tumor of the meninges above the exam
71.3
6.4
7
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
71.3
6.4
7
*
AA1AD
NOMESCO Finland
CT of head and brain
2.0
6.4
91
530
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
6.4
57
269
XKC03
NOMESCO Finland
Water cystometry
4.1
6.3
23
59
N28
ICPC
Limited function/disability (N)
7.3
6.3
14
20
22540
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal meninges
+∞
6.3
6
*
D33.47
ICD-10 Finland
Other benign neurofibromas in the nerve root of the spinal cord
+∞
6.3
6
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.6
6.1
45
192
N02AX02
ATC
tramadol; systemic, rectal
1.8
6.1
142
984
N06AA09
ATC
amitriptyline; systemic
2.5
6.0
47
205

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
259
1757
2.82
16.51
5.5
4.3
6.5
6.7
mmol/l
1.23
247
1628
165
908
2.55
16.25
2.8
2.3
—
—
—
0
0
18
21
8.98
14.25
2.3
1.0
—
—
—
0
0
84
355
2.80
13.83
5.0
6.3
0.5
1.4
mmol/l
1.31
59
294
68
270
2.88
12.49
1.4
1.4
—
—
—
0
0
46
145
3.50
12.43
5.0
7.7
23.9
24.8
mmol/l
1.47
46
135
24
46
5.53
12.19
2.3
1.0
—
—
—
0
0
133
738
2.29
12.04
3.8
3.5
92.8
92.1
%
0.12
127
721
122
680
2.22
10.70
2.9
2.2
—
—
—
0
0
152
936
2.10
10.23
2.5
2.0
220.0
173.0
u/l
0.29
140
882
205
1411
2.09
10.22
6.1
5.2
1.2
1.2
mmol/l
0.42
184
1278
198
1359
2.05
9.78
5.1
3.9
—
—
—
0
0
217
1542
2.07
9.72
7.2
5.9
1.2
1.2
mmol/l
0.17
186
1304
178
1201
1.98
8.96
2.4
2.2
—
—
—
0
0
144
968
1.83
6.81
6.8
5.2
—
—
—
0
0
173
1240
1.78
6.52
8.4
9.1
1.1
1.2
inr
1.06
44
359
149
1040
1.75
6.03
3.8
3.2
—
—
—
0
0
122
810
1.78
5.83
5.3
4.1
—
—
—
0
0
12
24
5.14
5.78
2.2
1.1
—
—
—
0
0
252
2076
1.76
5.31
5.9
4.6
—
—
—
0
0
61
335
1.99
5.21
1.6
1.6
—
—
—
0
0
50
255
2.12
5.21
1.8
2.7
66.4
66.7
g/l
0.09
41
228
188
1442
1.66
5.09
6.6
5.2
0.6
0.6
e9/l
0.32
154
1232
44
217
2.18
4.98
5.0
4.5
—
—
—
0
0
188
1449
1.64
4.94
6.6
5.3
0.0
0.0
e9/l
0.11
155
1239
190
1477
1.63
4.76
6.7
5.3
1.7
1.9
e9/l
1.79
160
1298
63
362
1.90
4.71
5.0
4.5
1.0
1.0
mmol/l
0.30
57
333
191
1495
1.61
4.59
6.9
5.5
0.2
0.2
e9/l
1.10
159
1304
44
226
2.08
4.50
1.8
2.5
—
—
—
0
0
174
1343
1.59
4.35
5.6
4.0
34.8
35.4
g/l
0.66
166
1249
148
1103
1.59
4.28
3.7
3.7
46.6
86.5
e6/l
1.15
105
781
171
1320
1.58
4.24
7.4
5.4
0.6
0.7
%
0.60
155
1215
32
148
2.28
4.23
6.9
7.6
—
—
—
0
0
18
62
3.01
4.23
1.8
1.0
67.5
8.5
e6/l
0.52
11
49
18
62
3.01
4.23
1.9
1.1
1434.2
154.5
e6/l
0.68
11
52
130
944
1.60
4.17
3.2
3.2
30.3
141.6
e6/l
0.90
97
722
121
866
1.61
4.11
3.2
3.1
0.7
0.5
e6/l
0.48
89
647
174
1356
1.56
4.09
7.3
5.4
2.5
2.8
%
1.19
157
1245
12
33
3.73
3.95
1.5
1.1
—
—
—
0
0
49
277
1.89
3.84
3.5
3.9
—
—
—
0
0
173
1362
1.53
3.79
7.6
5.6
8.6
8.6
%
0.01
157
1260
95
653
1.62
3.76
2.6
2.6
4.3
5.1
e6/l
0.41
84
576
90
611
1.64
3.74
2.0
1.7
1149.3
1211.4
nmol/l
0.27
66
447
69
437
1.72
3.72
2.3
2.0
—
—
—
0
0
175
1388
1.52
3.67
7.6
5.6
25.2
27.7
%
2.18
161
1277
43
237
1.93
3.63
5.6
4.4
0.5
1.0
%
1.08
16
73
195
1585
1.52
3.62
7.9
5.7
9.8
10.9
umol/l
1.65
182
1491
24
105
2.38
3.61
1.3
1.9
37.1
37.1
g/l
0.02
17
89
173
1373
1.51
3.59
7.0
5.3
60.4
57.3
%
2.51
158
1274
143
1093
1.52
3.53
3.5
3.2
2.3
2.4
mmol/l
0.28
124
945
123
917
1.53
3.38
3.6
2.2
54.3
57.4
u/l
0.48
113
840
40
222
1.91
3.32
5.8
4.5
0.0
0.2
%
1.98
14
65
9
19
4.83
3.26
2.1
2.1
—
—
—
0
0
10
28
3.65
3.22
1.9
1.4
—
—
—
0
0
314
2884
1.86
3.18
22.4
14.5
21.1
23.5
mg/l
0.87
283
2261
256
2240
1.53
3.10
4.9
4.2
13.9
13.3
mm/h
0.22
240
2039
112
837
1.50
2.99
3.3
3.0
—
—
—
0
0
86
609
1.55
2.94
2.9
2.7
518.4
544.6
mosm/kgh2o
0.58
71
510
100
732
1.51
2.94
2.7
2.1
3.4
3.2
mg/l
0.40
86
619
37
210
1.85
2.88
5.1
4.4
0.4
0.5
%
0.20
11
48
49
304
1.71
2.84
3.9
2.4
5.0
7.4
umol/l
1.79
43
266
58
378
1.64
2.80
1.7
1.3
—
—
—
0
0
37
213
1.82
2.76
2.4
2.9
9.1
10.4
g/l
1.29
32
198
201
1698
1.43
2.75
10.1
8.8
4.2
4.1
e9/l
0.22
173
1481
41
244
1.77
2.75
6.7
6.5
—
—
—
0
0
67
457
1.58
2.69
2.4
2.9
0.8
0.8
mmol/l
1.17
58
428
57
374
1.63
2.68
1.4
1.3
880.0
492.4
titre
0.44
12
90
12
43
2.85
2.67
4.5
3.7
0.3
1.2
%
—
6
34
15
61
2.52
2.65
1.2
1.2
—
—
—
0
0
36
209
1.81
2.62
6.0
4.6
0.2
0.2
%
0.03
12
54
33
189
1.82
2.52
7.8
2.7
4.0
4.1
e9/l
0.07
18
144
6
12
5.07
2.41
7.7
4.3
—
—
—
0
0
16
71
2.31
2.38
1.6
5.3
—
—
—
0
0
5
8
6.32
2.38
1.0
1.3
—
—
—
0
0
9
28
3.27
2.32
1.4
1.1
—
—
—
0
0
9
28
3.27
2.32
2.8
4.4
—
—
—
0
0
258
2315
1.44
2.30
10.5
7.1
78.9
78.7
u/l
0.02
248
2148
156
1293
1.37
2.23
2.2
2.0
94.5
96.3
pmol/l
0.15
82
628
11
42
2.67
2.20
1.5
1.8
89.2
90.4
%
0.30
11
42
145
1193
1.37
2.15
4.0
3.8
53.1
55.9
ng/l
0.03
111
881
24
131
1.89
2.14
4.7
4.8
—
—
—
0
0
12
49
2.50
2.12
1.6
1.9
—
—
—
0
0
65
464
1.49
2.12
2.7
2.2
11.3
13.0
umol/l
0.97
58
422
84
634
1.43
2.06
3.2
2.8
2.5
2.5
mmol/l
0.01
76
556
6
15
4.05
2.04
7.7
3.6
—
—
—
0
0
41
266
1.61
2.04
2.0
2.0
0.2
0.2
g/l
0.30
34
250
113
901
1.38
2.01
4.5
3.9
—
—
—
0
0
22
120
1.89
1.97
4.5
3.9
—
—
—
0
0
6
16
3.80
1.94
1.0
1.3
—
—
—
0
0
91
705
1.39
1.92
4.3
4.0
—
—
—
0
0
120
974
1.35
1.90
4.5
3.7
7.4
7.4
ph
1.11
22
186
96
753
1.38
1.88
1.5
1.6
21.4
21.7
nmol/l
0.05
76
637
6
17
3.57
1.84
1.0
1.2
—
—
—
0
0
98
774
1.37
1.83
7.2
6.6
—
—
—
0
0
291
2712
1.43
1.75
5.6
4.9
1.9
2.4
mu/l
0.50
264
2437
8
30
2.70
1.73
3.9
3.1
—
—
—
0
0
145
1228
1.31
1.67
3.3
2.7
153.6
114.3
ug/l
0.66
134
1109
6
19
3.19
1.67
2.0
2.3
—
—
—
0
0
5
14
3.61
1.62
1.0
1.0
—
—
—
0
0
155
1333
1.29
1.57
11.9
9.1
0.0
0.0
e9/l
0.51
126
1075
10
44
2.31
1.54
1.4
1.4
—
—
—
0
0
5
15
3.37
1.53
2.8
2.5
—
—
—
0
0
173
1513
1.28
1.53
4.8
4.1
0.0
0.0
estimate
0.00
31
270
6
21
2.89
1.51
1.0
1.3
—
—
—
0
0
14
72
1.98
1.51
1.6
1.4
31.4
28.6
iu/l
0.09
14
63
41
292
1.46
1.38
4.0
3.2
—
—
—
0
0
49
363
1.41
1.35
1.3
1.3
—
—
—
0
0
111
930
1.28
1.34
3.0
2.9
6.4
7.0
mmol/l
1.30
92
761
40
286
1.45
1.33
4.5
3.2
5.7
5.8
kpa
0.54
40
277
233
2138
1.27
1.30
4.3
4.0
—
—
—
0
0
53
401
1.38
1.29
2.8
2.3
21.8
22.2
%
0.05
45
341
9
44
2.07
1.27
1.0
1.2
—
—
—
0
0
82
666
1.30
1.25
2.0
1.7
483.0
9381317.3
pmol/l
0.50
65
533
6
25
2.42
1.25
1.0
1.1
—
1.4
—
0
6
34
239
1.47
1.24
2.8
2.9
67.1
71.4
e9/l
0.36
26
189
55
423
1.36
1.22
2.7
2.2
2.3
2.3
g/l
0.29
50
390
6
26
2.33
1.19
1.0
1.1
—
5.4
—
0
9
80
653
1.29
1.18
2.0
1.7
1.0
1.1
mg/l
0.17
64
522
66
526
1.31
1.16
1.4
1.3
20.2
38.3
iu/ml
1.35
22
166
5
20
2.52
1.15
1.0
1.2
—
—
—
0
0
168
1499
1.23
1.15
5.9
5.4
0.0
0.0
estimate
0.00
33
277
8
40
2.02
1.12
1.4
1.3
—
—
—
0
0
8
41
1.97
1.09
2.0
1.3
—
—
—
0
0
8
41
1.97
1.09
1.3
1.7
—
—
—
0
0
47
361
1.35
1.06
3.4
3.9
2.5
21.4
ug/l
0.99
38
304
72
590
1.28
1.03
4.6
3.7
135.0
143.2
ng/l
0.02
59
474
7
34
2.08
1.03
1.1
1.2
—
—
—
0
0
54
426
1.32
1.03
1.4
1.2
—
—
—
0
0
10
53
1.91
1.02
1.9
2.0
46.8
41.9
nmol/l
—
10
53
15
91
1.68
1.02
1.8
1.3
282.6
306.4
ug/g
—
10
52
110
949
1.23
1.01
3.7
3.8
14.4
7.2
mg/mmol
0.47
67
560
165
1484
1.21
1.01
4.7
4.0
0.0
0.0
estimate
0.00
30
278
15
92
1.66
0.98
3.9
3.2
—
—
—
0
0
288
2746
1.28
0.96
6.5
6.1
39.5
40.1
mmol/mol
0.53
259
2531
19
125
1.55
0.96
1.5
2.0
—
—
—
0
0
76
634
1.25
0.95
5.3
5.1
2.8
2.7
ug/l
0.04
67
566
318
3074
1.38
0.94
14.1
10.6
25.7
24.5
u/l
0.25
310
2949
11
183
0.59
0.94
1.3
1.3
—
—
—
0
0
6
27
2.24
0.94
1.2
1.4
—
—
—
0
0
16
102
1.60
0.92
4.4
2.8
0.4
0.2
g/l
—
7
33
23
160
1.47
0.91
3.7
3.9
—
—
—
0
0
12
71
1.71
0.90
1.2
1.7
—
—
—
0
0
69
573
1.25
0.89
1.5
1.4
2.0
2.5
g/l
1.65
37
324
39
301
1.33
0.87
1.5
1.5
—
—
—
0
0
43
338
1.31
0.85
1.6
1.7
—
—
—
0
0
49
393
1.29
0.84
31.7
23.0
1.5
1.3
inr
0.46
11
48
244
2299
1.20
0.84
4.8
4.1
15.1
14.9
pmol/l
0.72
219
2056
103
899
1.21
0.84
3.1
3.0
81.1
187.8
mg/l
0.46
64
544
80
929
0.82
0.82
3.0
3.1
—
—
—
0
0
6
33
1.83
0.79
1.2
1.8
—
—
—
0
0
27
200
1.38
0.79
3.8
3.2
—
—
—
0
0
9
53
1.72
0.76
1.0
1.3
—
—
—
0
0
9
54
1.68
0.75
1.0
1.3
—
—
—
0
0
9
54
1.68
0.75
1.0
1.3
—
—
—
0
0
9
54
1.68
0.75
1.0
1.3
—
—
—
0
0
29
220
1.35
0.74
1.1
1.1
—
—
—
0
0
71
605
1.22
0.74
5.3
4.7
—
—
—
0
0
9
55
1.65
0.74
1.0
1.3
—
—
—
0
0
7
39
1.81
0.73
1.7
3.1
—
—
—
0
0
16
109
1.49
0.72
1.1
1.0
—
—
—
0
0
34
266
1.31
0.71
1.4
1.5
—
—
—
0
0
5
26
1.94
0.71
1.0
1.0
—
—
—
0
0
14
93
1.53
0.70
1.1
1.1
—
—
—
0
0
11
69
1.61
0.69
1.5
2.3
—
—
—
0
0
5
28
1.80
0.66
1.2
1.1
—
—
—
0
0
18
129
1.42
0.65
1.2
1.4
—
—
—
0
0
34
271
1.28
0.64
3.0
2.5
3.8
4.9
ug/l
0.66
29
240
5
30
1.68
0.61
1.2
1.2
—
—
—
0
0
8
52
1.55
0.60
2.0
1.6
—
—
—
0
0
8
53
1.52
0.59
1.3
3.1
—
—
—
0
0
74
650
1.18
0.57
1.3
1.2
0.6
1.3
u/ml
1.23
16
164
11
74
1.50
0.54
1.4
2.4
1.1
1.6
mg/l
2.43
11
65
6
39
1.55
0.53
1.0
1.1
—
—
—
0
0
307
2994
1.21
0.52
20.9
13.7
—
—
—
0
0
22
171
1.31
0.51
1.2
1.4
—
—
—
0
0
79
707
1.15
0.49
1.4
1.3
—
—
—
0
0
91
823
1.14
0.48
5.7
4.4
0.0
0.0
estimate
0.00
33
274
7
47
1.50
0.48
1.3
1.1
34.2
20.7
u/l
—
7
40
7
48
1.47
0.47
1.6
1.5
—
—
—
0
0
13
94
1.40
0.46
4.5
4.5
—
—
—
0
0
294
2864
1.17
0.46
5.2
4.8
5.9
6.0
mmol/l
0.43
264
2587
12
87
1.39
0.42
1.0
1.1
—
—
—
0
0
5
32
1.57
0.42
1.4
1.3
—
—
—
0
0
5
32
1.57
0.42
1.2
1.0
—
—
—
0
0
262
2538
1.13
0.42
23.2
16.0
38.1
39.3
%
1.05
178
1728
5
33
1.52
0.41
1.0
1.0
—
—
—
0
0
8
59
1.36
0.41
2.5
1.6
—
—
—
0
0
12
88
1.38
0.40
5.4
9.7
—
—
—
0
0
13
170
0.76
0.39
1.4
1.4
—
—
—
0
0
5
36
1.39
0.38
1.0
1.4
—
—
—
0
0
73
802
0.89
0.38
4.9
3.8
—
—
—
0
0
38
328
1.18
0.38
2.1
2.0
70.5
136.0
ug/g
2.06
28
252
5
37
1.36
0.37
1.2
1.1
—
—
—
0
0
6
41
1.47
0.36
1.8
1.3
—
—
—
0
0
27
227
1.21
0.36
1.6
1.4
—
—
—
0
0
6
42
1.44
0.35
3.5
1.8
30.7
32.2
pg
—
6
42
42
369
1.16
0.34
2.9
3.1
1.2
0.7
ug/l
0.44
27
251
90
832
1.11
0.34
1.7
1.6
1.4
1.3
mmol/l
0.64
80
696
13
163
0.79
0.30
4.3
2.2
1.2
1.1
%
0.10
13
163
16
195
0.81
0.29
1.3
1.1
114.0
130.1
iu/ml
—
6
78
8
63
1.28
0.28
3.4
3.4
—
—
—
0
0
16
192
0.83
0.26
1.2
1.3
—
—
—
0
0
29
254
1.15
0.26
4.9
3.5
—
—
—
0
0
9
72
1.26
0.26
1.1
1.1
—
—
—
0
0
39
350
1.13
0.25
1.2
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
8
105
0.76
0.21
1.6
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
2.9
—
—
—
0
0
0
12
0.00
0.21
0.0
4.3
—
47.8
—
0
12
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
8.3
—
0
14
28
251
1.13
0.19
4.5
2.4
4.5
4.3
kpa
0.28
28
241
11
132
0.83
0.18
1.5
1.5
—
—
—
0
0
28
253
1.12
0.17
5.7
4.3
—
—
—
0
0
281
2845
0.94
0.15
5.0
4.6
1.5
1.5
mmol/l
0.07
251
2583
10
83
1.21
0.15
2.2
1.2
—
—
—
0
0
64
669
0.95
0.12
5.5
4.3
1.0
1.0
kg/l
0.50
11
87
25
267
0.93
0.08
1.6
1.6
—
—
—
0
0
5
62
0.80
0.08
3.6
2.3
—
—
—
0
0
240
2376
1.03
0.08
28.2
19.5
330.8
331.1
g/l
0.24
240
2359
6
70
0.85
0.07
2.2
2.2
—
—
—
0
0
12
108
1.12
0.07
1.6
1.7
—
—
—
0
0
9
105
0.85
0.06
1.6
1.2
—
—
—
0
0
12
111
1.08
0.04
1.5
1.3
—
—
—
0
0
11
102
1.08
0.03
1.6
1.8
20.7
21.2
s
0.19
11
93
17
162
1.05
0.02
2.5
2.4
—
—
—
0
0
17
162
1.05
0.02
1.2
1.3
—
—
—
0
0
274
2750
0.98
0.02
4.4
4.1
1.3
1.3
mmol/l
0.01
241
2478
49
499
0.98
0.02
1.3
1.3
2.4
13.7
u/ml
2.32
21
182
294
2932
1.02
0.01
5.5
5.3
2.7
2.7
mmol/l
0.10
264
2660
75
742
1.01
0.01
3.4
2.6
332.5
8438.7
umol/l
4.05
67
619
12
118
1.02
0.00
3.1
2.8
—
—
—
0
0
14
138
1.02
0.00
1.1
1.2
—
—
—
0
0
14
137
1.02
0.00
1.6
1.6
—
—
—
0
0
286
2864
0.99
0.00
5.0
4.7
4.6
4.7
mmol/l
0.32
258
2614
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
—
—
0
0
6
62
0.97
0.00
1.0
1.1
1.1
0.8
nmol/l
—
6
47
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
0.00
1.0
1.4
—
223.4
—
0
31
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
143.7
—
0
6
25
250
1.00
0.00
1.9
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_MENINGES_SPINAL and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MENINGES_SPINAL 1.32 [1.11, 1.57] 0.002
Birth year 0.995 [0.99, 1.0] 0.287

During the follow-up period (1.1.1998 — 31.12.2019), 262 out of 1097 females with CD2_BENIGN_MENINGES_SPINAL died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MENINGES_SPINAL 1.558 [1.19, 2.03] 0.001
Birth year 0.986 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 132 out of 448 males with CD2_BENIGN_MENINGES_SPINAL died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MENINGES_SPINAL.

N-year risk Females Males
1 0.099% 0.339%
5 0.788% 1.945%
10 2.149% 4.442%
15 3.812% 8.205%
20 6.545% 13.631%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_MENINGES_SPINAL – Benign neoplasm: Spinal meninges

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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