Benign neoplasm: Spinal meninges

CD2_BENIGN_MENINGES_SPINAL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D32.1&
  • Hospital discharge: ICD-9 2254
  • Hospital discharge: ICD-8 2254
  • Cause of death: ICD-10 D32.1&
  • Cause of death: ICD-9 2254
  • Cause of death: ICD-8 2254

2 out of 7 registries used, show all original rules.

377

4. Check minimum number of events

None

377

5. Include endpoints

None

377

6. Filter based on genotype QC (FinnGen only)

365

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D32
Name in latin
Neoplasma benignum meningum spinalium

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2153 1510 634
Only index persons 1841 1306 535
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.02
Only index persons 0.04 0.05 0.02
Median age at first event (years)
Whole population 62.54 63.92 59.41
Only index persons 61.91 63.16 58.86

-FinnGen-

Key figures

All Female Male
Number of individuals 365 266 99
Unadjusted period prevalence (%) 0.08 0.09 0.05
Median age at first event (years) 62.51 62.55 62.40

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
377
Matched controls
3770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
+∞
307.7
352
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
216.1
186
*
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
70.2
164.1
91
17
9530/0-C70.1
ICD-O-3
Meningioma, NOS, of spinal meninges
+∞
82.4
76
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
37.5
82.1
52
16
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
32.6
77.1
51
18
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
22.1
59.0
45
23
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
101.7
55.8
60
7
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.8
48.4
89
165
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
12.7
47.6
49
44
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
7.1
34.0
55
88
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
124.2
32.2
34
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.0
31.1
113
363
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
74.4
30.4
34
5
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
156.6
28.0
29
*
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
28.2
26.7
36
14
2254A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal meninges
+∞
23.2
22
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
89.1
23.0
25
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
244.2
22.9
23
*
N03AX12
ATC
[U] gabapentin; oral
3.2
22.0
111
431
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
21.3
146
672
9560/0-C72.0
ICD-O-3
Schwannoma, NOS, of spinal cord
+∞
21.0
20
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
17.7
20.0
31
19
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
+∞
20.0
19
*
NA7FT
NOMESCO Finland
Labeling lesion in spinal area with X-ray guidance
210.6
19.7
20
*
N03AX16
ATC
[U] pregabalin
2.8
19.5
137
635
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
19.2
91
338
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
18.9
18
*
2312
FHL
Extirpation or destruction
+∞
18.9
18
*
D33.43
ICD-10 Finland
Spinal cord
+∞
18.9
18
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.5
18.1
71
234
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.2
17.6
51
136
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
177.5
16.6
17
*
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
15.7
15
*
G82.2
ICD-10 Finland
Paraplegia, unspecified
23.3
15.7
22
10
R20.2
ICD-10 Finland
Paraesthesia of skin
3.9
15.6
49
138
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.8
14.3
34
77
M03BX01
ATC
baclofen; systemic
6.7
14.3
23
36
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.3
13.6
55
183
G992, D321,
ICD-10 Finland
+∞
13.6
13
*
N75
ICPC
Benign neoplasm nervous system
+∞
13.6
13
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
13.5
13.6
23
18
AA1BD
NOMESCO Finland
Extensive CT of head and brain
6.1
12.9
23
40
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.3
12.7
22
37
9531/0-C70.1
ICD-O-3
Meningothelial meningioma of spinal meninges
+∞
12.6
12
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
134.3
12.5
13
*
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
38.9
12.3
15
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.1
11.6
25
52
XKD06
NOMESCO Finland
Physiologic investigation of micturition
4.9
11.1
25
54
L28
ICPC
Limited function/disability (L)
2.3
10.8
98
494
N06AX21
ATC
duloxetine; oral
2.6
10.0
64
274
XKD00
NOMESCO Finland
Uroflowmetry
2.6
9.9
64
275
N02BF01
ATC
gabapentin; oral
2.8
9.6
50
192
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
10.4
9.6
18
18
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
+∞
9.4
9
*
D42.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal meninges
+∞
9.4
9
*
9537/0-C70.1
ICD-O-3
Transitional meningioma of spinal meninges
+∞
9.4
9
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
+∞
9.4
9
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
14.1
9.3
15
11
N06AA09
ATC
amitriptyline; systemic
2.6
9.1
57
241
R4110
NOMESCO Finland
Physiotherapy
2.0
8.9
130
783
N28
ICPC
Limited function/disability (N)
7.9
8.8
19
25
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.9
8.7
44
166
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
51.2
8.7
10
*
WX402
NOMESCO Finland
General anaesthesia
2.2
8.6
90
477
M48.0
ICD-10 Finland
Spinal stenosis
2.3
8.6
71
341
D33.30
ICD-10 Finland
Acoustic neuroma
16.8
8.6
13
8
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
92.0
8.4
9
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
92.0
8.4
9
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.3
8.4
22
54
D33.47
ICD-10 Finland
Other benign neurofibromas in the nerve root of the spinal cord
+∞
8.4
8
*
D33.46
ICD-10 Finland
Benign neurofibroma in the nerve root of the spinal cord
+∞
8.4
8
*
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
+∞
8.4
8
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
8.4
8
*
22540
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal meninges
+∞
8.4
8
*
XKC03
NOMESCO Finland
Water cystometry
3.9
8.2
24
64
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
6.5
8.1
20
32
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
34.1
8.1
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
8.1
94
518
N02BE01
ATC
paracetamol; systemic, rectal
3.2
8.1
351
3055
N18
ICPC
Paralysis/weakness
6.6
7.8
19
30
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
7.8
56
253
AA1AD
NOMESCO Finland
CT of head and brain
1.9
7.8
120
731
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.7
7.7
18
40
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
25.6
7.6
10
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
7.5
177
1232
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
81.6
7.4
8
*
AWW99
NOMESCO Finland
Other reoperation in surgery of the nervous system
81.6
7.4
8
*
ZXD35
NOMESCO Finland
Usual procedure
4.0
7.4
21
55
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
+∞
7.3
7
*
D32.04
ICD-10 Finland
Secondary or multiple benign tumor of the meninges above the exam
30.6
7.2
9
*
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
30.6
7.2
9
*
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.6
7.0
23
67
N02BF02
ATC
pregabalin; oral
2.8
6.9
34
127
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
40.8
6.8
8
*
H02AB02
ATC
dexamethasone; systemic
2.2
6.7
59
290
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
6.7
153
1045
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
6.7
38
153
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
6.6
264
2113
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
6.5
72
387
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
6.4
29
103
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
6.3
78
436
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
11.3
6.3
11
10
M54.2
ICD-10 Finland
Cervicalgia
2.6
6.3
38
158
AAK00
NOMESCO Finland
Cranioplasty
+∞
6.3
6
*
9533/0-C70.1
ICD-O-3
Psammomatous meningioma of spinal meninges
+∞
6.3
6
*
9539/1-C70.1
ICD-O-3
Atypical meningioma of spinal meninges
+∞
6.3
6
*
ABC63
NOMESCO Finland
Decompression of thoracic spinal cord
27.2
6.3
8
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
6.1
131
873
ZXC40
NOMESCO Finland
Use of ultrasound
12.8
6.1
10
8
N03AX14
ATC
levetiracetam; systemic
5.3
6.1
17
33

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
279
1892
2.83
17.77
5.3
4.3
6.44
6.69
mmol/l
1.43
266
1759
175
984
2.45
16.06
2.7
2.3
—
—
—
0
0
91
377
2.86
15.57
4.8
6.3
0.61
1.35
mmol/l
1.08
66
315
51
157
3.60
14.27
4.7
7.8
24.03
24.74
mmol/l
1.27
51
152
73
298
2.80
12.66
1.4
1.4
—
—
—
0
0
142
797
2.25
12.36
3.7
3.6
93.41
92.32
%
0.20
135
776
237
1675
2.12
10.96
6.9
5.9
1.21
1.22
mmol/l
0.30
206
1424
24
51
4.96
10.87
2.3
1.0
—
—
—
0
0
222
1535
2.09
10.84
5.8
5.3
1.21
1.22
mmol/l
0.49
200
1393
130
746
2.13
10.38
2.8
2.2
—
—
—
0
0
162
1011
2.06
10.33
2.5
2.0
212.24
168.99
u/l
0.29
149
952
194
1310
1.99
9.75
2.3
2.2
—
—
—
0
0
211
1479
1.97
9.39
3.3
2.5
—
—
—
0
0
18
24
7.82
8.26
2.3
1.0
—
—
—
0
0
206
1547
1.73
6.34
14.8
14.2
1.18
1.26
inr
0.69
55
445
55
275
2.17
6.00
1.8
2.7
66.50
66.60
g/l
0.04
46
246
37
157
2.50
5.85
6.2
7.5
—
—
—
0
0
47
226
2.23
5.63
4.8
4.4
—
—
—
0
0
192
1451
1.66
5.49
7.3
6.0
—
—
—
0
0
128
875
1.70
5.34
5.2
4.1
—
—
—
0
0
270
2246
1.71
5.19
5.8
4.5
—
—
—
0
0
49
248
2.12
5.18
1.7
2.4
—
—
—
0
0
70
407
1.88
5.02
4.3
5.7
105.60
104.17
mmol/l
2.14
70
407
30
125
2.52
4.94
1.3
1.9
9.14
10.05
g/l
1.28
23
109
154
1124
1.63
4.90
3.8
3.2
—
—
—
0
0
200
1558
1.60
4.84
6.5
5.3
0.57
0.58
e9/l
0.37
164
1339
200
1563
1.60
4.74
6.5
5.3
0.04
0.04
e9/l
0.35
164
1343
63
364
1.88
4.59
1.6
1.6
—
—
—
0
0
202
1594
1.58
4.51
6.6
5.4
1.69
1.93
e9/l
1.72
170
1412
41
207
2.10
4.37
2.7
2.4
—
15.37
—
0
9
203
1615
1.56
4.30
6.8
5.6
0.17
0.19
e9/l
1.17
169
1412
26
109
2.49
4.25
1.3
2.0
37.74
37.37
g/l
0.08
19
94
66
401
1.78
4.09
4.8
4.5
1.05
1.02
mmol/l
0.29
60
368
185
1454
1.53
4.06
5.4
4.1
34.76
35.44
g/l
0.85
177
1354
156
1184
1.54
4.00
3.7
3.8
45.00
82.76
e6/l
1.14
109
834
12
27
4.55
3.97
2.2
1.1
—
—
—
0
0
211
1712
1.53
3.95
7.5
5.7
12.00
10.91
umol/l
0.20
198
1610
181
1423
1.52
3.92
7.3
5.4
0.63
0.68
%
0.71
166
1306
18
65
2.86
3.91
1.8
1.0
67.45
8.40
e6/l
0.52
11
50
18
65
2.86
3.91
1.9
1.1
1434.18
153.17
e6/l
0.68
11
53
136
1007
1.55
3.87
3.2
3.3
29.24
135.36
e6/l
0.92
101
771
127
927
1.56
3.85
3.2
3.2
0.71
0.50
e6/l
0.45
96
695
54
315
1.83
3.81
3.4
3.8
—
—
—
0
0
341
3119
1.98
3.79
21.8
14.6
21.01
23.63
mg/l
1.03
304
2445
134
994
1.54
3.77
3.4
2.2
54.08
65.45
u/l
1.11
123
910
79
519
1.66
3.69
2.5
2.9
1.97
2.73
e6/l
0.55
42
272
184
1465
1.50
3.68
7.2
5.4
2.54
2.83
%
0.98
168
1347
279
2429
1.57
3.61
5.1
4.2
13.75
13.18
mm/h
0.22
261
2207
73
474
1.67
3.56
2.3
2.0
—
—
—
0
0
183
1471
1.47
3.41
7.7
5.7
8.59
8.61
%
0.02
167
1358
184
1481
1.47
3.40
7.0
5.4
60.05
57.27
%
2.12
169
1372
45
258
1.85
3.36
5.3
4.5
0.75
0.94
%
0.25
20
96
185
1498
1.46
3.28
7.6
5.6
25.41
27.73
%
1.94
171
1386
98
698
1.55
3.25
2.5
2.7
4.43
6.29
e6/l
0.73
88
631
93
655
1.56
3.24
1.9
1.7
1136.13
1229.32
nmol/l
0.46
68
477
45
265
1.79
3.10
6.3
6.4
—
—
—
0
0
42
243
1.82
3.06
5.5
4.6
0.00
0.14
%
1.97
17
81
93
663
1.53
3.05
3.2
2.9
516.64
533.88
mosm/kgh2o
0.36
78
559
9
21
4.36
3.01
2.1
2.0
—
—
—
0
0
107
789
1.50
2.99
2.8
2.1
3.36
3.22
mg/l
0.22
93
662
12
38
3.23
2.87
1.5
1.2
—
—
—
0
0
149
1183
1.43
2.82
3.4
3.3
2.35
2.36
mmol/l
0.44
130
1033
227
1946
1.42
2.76
4.3
2.9
46.78
46.96
u/l
0.01
213
1797
281
2506
1.48
2.75
10.0
7.1
79.42
78.33
u/l
0.17
271
2327
16
66
2.49
2.74
1.2
1.2
—
—
—
0
0
117
895
1.45
2.69
3.3
3.1
—
—
—
0
0
39
230
1.78
2.68
5.9
4.7
0.14
0.16
%
0.03
14
69
39
230
1.78
2.68
5.2
4.6
0.39
0.56
%
0.40
18
76
168
1372
1.40
2.68
2.4
2.3
77.75
79.26
nmol/l
0.37
151
1198
72
501
1.54
2.62
2.3
2.8
0.84
0.81
mmol/l
1.27
63
468
107
808
1.45
2.62
1.4
1.6
21.27
21.92
nmol/l
0.16
86
685
170
1396
1.40
2.60
2.1
2.0
95.62
95.99
pmol/l
0.03
89
678
60
404
1.58
2.52
1.4
1.3
824.62
470.30
titre
0.43
13
99
157
1281
1.39
2.46
3.9
3.8
54.18
57.52
ng/l
0.03
120
941
10
32
3.18
2.45
1.9
1.4
—
—
—
0
0
35
207
1.76
2.40
7.4
2.9
4.12
7.72
e9/l
0.99
20
167
5
8
6.31
2.38
1.0
1.3
—
—
—
0
0
213
1834
1.37
2.36
9.9
8.9
4.15
4.10
e9/l
0.11
183
1605
6
13
4.67
2.28
7.7
4.0
—
—
—
0
0
37
227
1.70
2.25
2.4
3.0
9.14
10.39
g/l
1.32
32
211
50
333
1.58
2.21
3.9
2.4
5.09
7.20
umol/l
1.69
44
290
9
30
3.05
2.16
1.4
1.2
—
—
—
0
0
59
412
1.51
2.12
1.7
1.3
—
—
—
0
0
16
75
2.18
2.11
1.6
5.2
—
—
—
0
0
9
31
2.95
2.08
2.8
4.1
—
—
—
0
0
25
140
1.84
2.06
4.6
4.6
—
—
—
0
0
6
15
4.05
2.04
2.7
2.5
—
—
—
0
0
123
989
1.36
2.04
4.4
4.0
—
—
—
0
0
24
134
1.84
2.00
4.9
3.8
—
—
—
0
0
6
16
3.79
1.94
1.0
1.3
—
—
—
0
0
67
490
1.45
1.92
2.8
2.2
11.16
13.03
umol/l
1.17
61
451
11
46
2.43
1.87
1.5
1.9
89.15
90.24
%
0.27
11
46
88
680
1.38
1.86
3.1
2.8
2.46
2.46
mmol/l
0.01
80
596
97
762
1.37
1.85
4.1
3.9
—
—
—
0
0
128
1050
1.33
1.84
4.3
3.7
7.41
7.40
ph
0.79
24
197
157
1329
1.31
1.80
3.3
2.7
150.14
112.97
ug/l
0.68
146
1202
167
1427
1.31
1.78
11.5
9.3
0.00
0.00
e9/l
0.62
135
1158
8
30
2.70
1.73
3.6
2.9
—
—
—
0
0
5
13
3.88
1.72
1.2
1.9
—
—
—
0
0
187
1628
1.29
1.72
4.7
4.0
0.00
0.01
estimate
0.50
32
285
315
2950
1.41
1.71
5.5
5.0
1.78
2.37
mu/l
0.80
287
2659
43
295
1.52
1.70
2.0
2.0
0.20
0.21
g/l
0.39
35
278
12
55
2.22
1.69
1.6
1.9
—
—
—
0
0
122
1009
1.31
1.63
3.0
3.0
6.35
7.03
mmol/l
1.42
103
834
10
43
2.36
1.60
1.2
1.6
—
—
—
0
0
7
26
2.72
1.58
1.0
1.1
—
1.43
—
0
7
11
50
2.24
1.58
1.4
1.4
—
—
—
0
0
5
15
3.36
1.53
1.0
1.0
—
—
—
0
0
253
2310
1.29
1.52
4.2
4.0
—
—
—
0
0
44
311
1.47
1.52
4.3
3.1
5.70
5.83
kpa
0.45
44
302
6
21
2.89
1.51
1.0
1.2
—
—
—
0
0
17
94
1.85
1.50
3.6
3.1
—
—
—
0
0
62
471
1.38
1.45
1.4
1.2
—
—
—
0
0
5
16
3.15
1.44
2.0
2.3
545.20
760.50
u/ml
—
5
16
5
16
3.15
1.44
2.8
1.5
44.54
40.81
%
—
5
16
182
1604
1.26
1.43
4.5
4.0
0.00
0.00
estimate
-0.00
35
316
42
300
1.45
1.39
2.1
2.2
28.31
29.73
u/l
0.16
36
248
88
711
1.31
1.38
2.0
1.7
482.13
8772381.57
pmol/l
0.50
70
570
9
41
2.22
1.38
1.3
1.3
—
—
—
0
0
6
23
2.63
1.37
1.0
1.3
—
—
—
0
0
6
23
2.63
1.37
2.0
2.3
—
—
—
0
0
5
17
2.97
1.36
1.4
3.9
56.80
97.76
nmol/l
—
5
17
182
1613
1.25
1.34
5.9
5.4
0.00
0.00
estimate
-0.00
34
294
15
83
1.84
1.33
4.2
2.7
—
—
—
0
0
15
83
1.84
1.33
1.7
1.4
30.07
29.13
iu/l
0.03
15
70
100
829
1.28
1.29
7.1
6.7
—
—
—
0
0
21
132
1.63
1.23
1.5
2.0
—
—
—
0
0
55
427
1.34
1.14
2.9
2.3
21.85
22.10
%
0.03
46
364
345
3328
1.43
1.14
13.7
10.6
26.01
24.51
u/l
0.37
336
3192
120
1031
1.24
1.14
3.6
3.7
13.42
7.18
mg/mmol
0.43
72
610
114
976
1.24
1.11
3.1
3.1
531.31
250.24
mg/l
0.26
71
594
18
112
1.64
1.11
4.0
2.8
0.36
0.20
g/l
—
7
36
5
21
2.40
1.09
1.0
1.2
—
—
—
0
0
77
631
1.28
1.09
4.5
3.7
126.78
170.11
ng/l
0.15
63
504
76
622
1.28
1.09
1.5
1.4
1.97
2.44
g/l
1.99
40
348
16
97
1.68
1.08
1.8
1.3
300.18
305.79
ug/g
0.04
11
56
57
449
1.32
1.08
2.8
2.2
2.28
2.35
g/l
0.39
52
413
50
387
1.34
1.07
3.3
4.0
2.47
20.19
ug/l
1.00
40
328
312
2975
1.28
1.04
6.4
6.1
39.63
40.03
mmol/mol
0.34
281
2737
9
46
1.98
1.04
1.0
1.2
—
—
—
0
0
51
398
1.33
1.03
1.3
1.3
—
—
—
0
0
86
719
1.25
1.03
1.9
1.6
1.01
1.12
mg/l
0.19
68
567
35
257
1.40
1.03
2.7
2.8
67.96
71.61
e9/l
0.30
27
199
10
53
1.91
1.02
1.9
2.0
46.80
41.92
nmol/l
—
10
53
70
572
1.27
1.02
1.4
1.3
34.12
40.43
iu/ml
0.15
24
178
25
173
1.48
1.00
3.6
3.8
—
—
—
0
0
85
714
1.25
0.98
1.3
1.2
0.97
1.39
u/ml
0.36
19
173
5
23
2.19
0.98
1.0
1.1
—
—
—
0
0
9
50
1.82
0.97
1.4
1.5
—
—
—
0
0
13
77
1.71
0.96
1.2
1.6
—
—
—
0
0
6
27
2.24
0.94
1.0
1.0
—
—
—
0
0
29
210
1.41
0.93
4.4
3.2
—
—
—
0
0
117
1022
1.21
0.93
3.1
3.0
1466.55
1149.98
ng/l
0.37
107
867
9
52
1.75
0.93
1.2
1.2
30.03
19.87
u/l
—
9
45
18
118
1.55
0.92
1.2
1.0
—
—
—
0
0
87
1013
0.82
0.90
3.0
3.2
—
—
—
0
0
6
29
2.09
0.89
1.2
1.4
—
—
—
0
0
24
170
1.44
0.87
1.6
3.0
0.33
0.17
e6/l
0.35
24
165
90
771
1.22
0.87
1.4
1.3
—
—
—
0
0
79
668
1.23
0.86
5.2
5.0
2.75
2.65
ug/l
0.06
70
598
8
44
1.84
0.86
2.0
1.3
—
—
—
0
0
8
44
1.84
0.86
1.6
3.1
—
—
—
0
0
6
31
1.95
0.84
1.3
1.5
42.10
42.93
u/l
—
6
26
10
58
1.74
0.80
1.0
1.4
—
—
—
0
0
10
58
1.74
0.80
1.0
1.4
—
—
—
0
0
10
58
1.74
0.80
1.0
1.4
—
—
—
0
0
6
34
1.78
0.76
1.2
1.1
—
—
—
0
0
10
59
1.71
0.76
1.0
1.4
—
—
—
0
0
9
53
1.71
0.76
1.9
1.6
—
—
—
0
0
32
247
1.32
0.73
1.1
1.1
—
—
—
0
0
41
329
1.28
0.71
1.5
1.5
—
—
—
0
0
7
40
1.76
0.71
1.1
1.2
—
—
—
0
0
9
57
1.59
0.71
1.0
1.4
—
—
—
0
0
15
101
1.51
0.71
4.2
4.4
—
—
—
0
0
262
2494
1.17
0.68
4.8
4.1
15.12
14.88
pmol/l
0.71
237
2233
14
200
0.69
0.65
1.4
1.3
—
—
—
0
0
45
371
1.24
0.64
1.5
1.7
—
—
—
0
0
98
872
1.17
0.63
5.4
4.4
0.00
0.00
estimate
-0.00
34
289
141
1294
1.14
0.60
4.2
3.7
6.20
5.82
ph
—
5
86
35
283
1.26
0.59
1.5
1.5
—
—
—
0
0
320
3108
1.20
0.58
5.2
4.9
5.90
5.96
mmol/l
0.49
289
2808
6
35
1.73
0.58
1.2
1.8
—
—
—
0
0
12
81
1.50
0.57
1.9
2.3
1.17
1.54
mg/l
1.84
12
72
14
98
1.45
0.57
1.0
1.1
—
—
—
0
0
43
360
1.22
0.55
2.1
2.1
67.34
135.26
ug/g
2.41
32
273
9
61
1.49
0.54
2.3
1.6
—
—
—
0
0
6
39
1.55
0.53
1.5
2.1
—
—
—
0
0
331
3236
1.19
0.48
20.5
13.7
—
—
—
0
0
35
292
1.22
0.47
3.0
2.6
3.69
4.95
ug/l
0.75
30
260
348
3421
1.22
0.44
31.7
21.7
39.12
39.65
%
0.87
337
3185
348
3421
1.22
0.44
32.0
21.7
254.52
250.09
e9/l
0.59
343
3324
44
379
1.18
0.43
1.3
1.3
—
—
—
0
0
99
906
1.13
0.43
1.7
1.7
1.42
1.33
mmol/l
0.59
88
754
45
389
1.18
0.43
2.8
3.1
1.12
0.73
ug/l
0.42
29
259
5
32
1.57
0.42
1.2
1.2
—
—
—
0
0
13
96
1.37
0.42
5.1
9.4
—
—
—
0
0
0
17
0.00
0.40
0.0
2.1
—
8.82
—
0
17
23
187
1.24
0.40
1.2
1.3
—
—
—
0
0
8
61
1.32
0.39
1.3
3.0
—
—
—
0
0
5
35
1.43
0.39
1.2
1.0
—
—
—
0
0
32
272
1.19
0.37
4.3
2.4
4.39
4.36
kpa
0.03
32
262
9
69
1.31
0.37
3.1
3.2
—
—
—
0
0
32
273
1.19
0.36
4.5
3.5
—
—
—
0
0
9
71
1.27
0.36
1.1
1.1
—
82.00
—
0
5
6
41
1.47
0.36
1.0
1.1
—
—
—
0
0
14
108
1.31
0.36
1.1
1.1
—
—
—
0
0
21
172
1.23
0.35
1.2
1.3
—
—
—
0
0
6
44
1.37
0.34
1.8
1.3
—
—
—
0
0
6
47
1.28
0.32
3.5
1.7
30.67
32.45
pg
—
6
47
79
855
0.90
0.31
4.9
3.8
—
—
—
0
0
15
183
0.81
0.28
1.4
1.4
—
—
—
0
0
14
113
1.25
0.27
1.5
1.7
—
—
—
0
0
29
254
1.15
0.26
1.6
1.4
—
—
—
0
0
26
296
0.87
0.24
1.5
1.5
—
—
—
0
0
5
38
1.32
0.23
1.0
1.4
—
—
—
0
0
5
38
1.32
0.23
1.0
1.0
—
—
—
0
0
10
79
1.27
0.22
1.1
1.1
—
—
—
0
0
5
41
1.22
0.22
1.2
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
304
3085
0.92
0.21
5.0
4.6
1.51
1.53
mmol/l
0.21
275
2800
20
173
1.16
0.21
2.5
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
171.92
—
0
12
11
89
1.24
0.21
1.5
1.2
—
2.48
—
0
13
0
13
0.00
0.21
0.0
4.1
—
49.65
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
9
111
0.81
0.20
1.6
1.2
—
—
—
0
0
6
50
1.20
0.20
1.3
1.1
—
—
—
0
0
19
217
0.87
0.19
1.3
1.3
—
—
—
0
0
19
216
0.87
0.18
1.2
1.2
87.32
138.67
iu/ml
—
8
82
5
66
0.75
0.17
3.6
2.2
—
—
—
0
0
10
115
0.87
0.11
2.0
1.8
—
—
—
0
0
16
176
0.91
0.09
3.8
2.2
1.14
1.14
%
0.00
16
176
10
87
1.15
0.09
2.2
1.2
—
—
—
0
0
6
75
0.80
0.07
2.2
2.0
—
—
—
0
0
14
152
0.92
0.06
1.6
1.5
—
—
—
0
0
13
119
1.10
0.06
1.5
1.3
—
—
—
0
0
309
3104
0.97
0.04
5.0
4.7
4.68
4.69
mmol/l
0.08
282
2832
16
170
0.94
0.04
3.8
2.2
0.65
0.65
%
0.02
16
170
79
802
0.98
0.03
3.3
2.6
329.47
8218.84
umol/l
4.28
70
675
28
271
1.04
0.02
5.7
4.3
—
—
—
0
0
319
3180
1.02
0.02
5.5
5.3
2.76
2.74
mmol/l
0.15
290
2884
53
539
0.98
0.02
1.3
1.3
2.29
13.09
u/ml
2.47
23
199
297
2979
0.99
0.01
4.3
4.2
1.28
1.27
mmol/l
0.12
263
2683
14
146
0.96
0.00
1.1
1.2
—
—
—
0
0
14
146
0.96
0.00
1.6
1.6
—
—
—
0
0
71
711
1.00
0.00
5.1
4.3
1.01
1.02
kg/l
0.53
11
95
29
287
1.01
0.00
1.8
1.5
—
—
—
0
0
12
125
0.96
0.00
3.1
2.8
—
—
—
0
0
257
2565
1.01
0.00
27.7
19.5
330.93
331.12
g/l
0.13
257
2546
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.6
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
55
0.91
-0.00
4.8
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.1
1.06
0.85
nmol/l
—
6
51
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.6
2.5
106.00
105.96
mmol/l
—
5
50
0
6
0.00
-0.00
0.0
2.3
—
143.67
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
-0.00
1.6
2.5
4.20
3.99
mmol/l
—
5
50
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MENINGES_SPINAL and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MENINGES_SPINAL 1.32 [1.11, 1.57] 0.002
Birth year 0.995 [0.99, 1.0] 0.287

During the follow-up period (1.1.1998 — 31.12.2019), 262 out of 1097 females with CD2_BENIGN_MENINGES_SPINAL died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MENINGES_SPINAL 1.558 [1.19, 2.03] 0.001
Birth year 0.986 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 132 out of 448 males with CD2_BENIGN_MENINGES_SPINAL died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MENINGES_SPINAL.

N-year risk Females Males
1 0.099% 0.339%
5 0.788% 1.945%
10 2.149% 4.442%
15 3.812% 8.205%
20 6.545% 13.631%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MENINGES_SPINAL – Benign neoplasm: Spinal meninges

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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