Transient retinal artery occlusion

H7_RETARTOCCTRANS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H34.0 Cause of death: ICD-10 — H34.0 2 out of 7 registries used, show all original rules.	79
4. Check minimum number of events None	79
5. Include endpoints None	79
6. Filter based on genotype QC (FinnGen only)	78

Control definitions (FinnGen only)

Control exclude: H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H34
Name in latin: Occlusio arteriae retinalis transitoria

NAME	H7_RETARTOCCTRANS
CONTROL_EXCLUDE	H7_CHOROIDRETINA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H340
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H340
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Transient retinal artery occlusion based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	494	232	259
Only index persons	457	219	238
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	69.25	71.14	67.63
Only index persons	68.72	70.55	67.03

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	78	40	38
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	65.19	64.18	66.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
79: Matched controls
790

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H34.0

ICD-10 Finland

Transient retinal artery occlusion

+∞

113.6

H34.2

ICD-10 Finland

Other retinal artery occlusions

+∞

19.6

H34.8

ICD-10 Finland

Other retinal vascular occlusions

213.2

17.2

XCK10

NOMESCO Finland

Photography of fundus of eye

8.5

15.8

H34.1

ICD-10 Finland

Central retinal artery occlusion

+∞

15.1

CKC12

NOMESCO Finland

Photocoagulation of retina

167.6

13.9

CK2S4

NOMESCO Finland

Plain photography of ocular fundus

15.1

11.0

CKD05

NOMESCO Finland

Puncture of vitreous body with injection of medication

126.1

10.7

Z01.0

ICD-10 Finland

Examination of eyes and vision

4.9

9.6

CK2X4

NOMESCO Finland

Optical coherence tomography (OCT) of ocular fundus

8.9

9.3

XCD20

NOMESCO Finland

Photoangiography of eye

100.3

8.6

XCW99

NOMESCO Finland

Other investigative procedure of eye

8.0

7.6

XCK00

NOMESCO Finland

Perimetry

8.1

7.3

AA1AD

NOMESCO Finland

CT of head and brain

3.5

7.0

165

G45.3

ICD-10 Finland

Amaurosis fugax

20.0

6.4

H35.39

ICD-10 Finland

Degeneration of macula and posterior pole

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3013826) Glucose [Moles/volume] in Serum or Plasma

416

2.84

3.92

6.3

4.3

6.39

6.78

mmol/l

1.18

392

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

337

2.45

3.52

9.0

6.2

1.22

1.21

mmol/l

0.25

287

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.85

3.28

5.5

6.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

8.00

3.11

1.0

1.1

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

293

2.25

3.07

6.6

4.2

35.76

34.88

g/l

0.59

283

(3009445) Proteinase 3 Ab [Units/volume] in Serum

3.82

3.04

1.2

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

4.48

2.98

1.2

1.1

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

252

2.08

2.59

2.6

2.1

81.33

78.70

nmol/l

0.21

217

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

5.31

2.45

2.8

1.8

104.50

93.92

—

(3052851) Hemolysis interference index of Serum or Plasma

3.92

2.44

2.9

3.0

—

(3035350) Ketones [Presence] in Urine by Test strip

332

2.03

2.38

6.6

4.0

0.00

0.01

estimate

—

(3027945) Reticulocytes/100 erythrocytes in Blood

2.40

2.33

5.6

3.1

1.80

1.67

0.24

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

4.16

2.31

2.7

1.2

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

2.63

2.26

1.9

2.1

0.21

0.20

g/l

0.26

(3000991) Gas panel - Venous blood

2.53

2.23

7.1

7.0

—

(3022217) INR in Platelet poor plasma by Coagulation assay

318

1.96

2.23

32.2

14.7

1.38

1.26

inr

0.35

110

(3009261) Glucose [Presence] in Urine by Test strip

338

1.96

2.20

6.7

4.0

0.00

estimate

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.21

2.13

6.7

5.8

103.00

104.13

mmol/l

0.40

(3044290) Cell count panel - Cerebral spinal fluid

4.23

2.08

1.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

334

1.90

2.04

9.3

5.5

0.00

estimate

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

109

2.12

2.00

3.4

2.1

2.19

2.31

g/l

0.33

(3000492) Spirometry study

2.54

1.99

1.6

1.5

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

4.77

1.97

2.6

1.9

172.20

201.45

—

(3018418) pH of Serum or Plasma

217

1.89

1.96

4.5

4.3

7.39

7.41

—

(3019150) Specific gravity of Urine by Refractometry

134

2.01

1.93

7.1

4.5

1.02

1.01

kg/l

—

(3023520) Reticulocytes [#/volume] in Blood

2.49

1.92

3.1

3.4

72.41

67.87

e9/l

—

(3037467) Urinalysis macro (dipstick) panel - Urine

451

1.95

1.87

7.1

4.4

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

275

1.83

1.84

5.2

4.1

39.44

36.66

ng/l

0.06

202

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

276

1.82

1.81

2.5

1.9

93.35

92.73

pmol/l

0.03

122

(3012516) Albumin [Mass/volume] in Urine

187

1.87

1.81

4.8

3.0

103.19

45.20

mg/l

0.34

122

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

4.03

1.74

1.0

1.2

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.75

1.71

1.3

2.0

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.33

1.69

1.2

1.6

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.33

1.69

1.2

1.6

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

2.97

1.69

1.9

1.6

—

(3021960) Folate [Moles/volume] in Serum or Plasma

174

1.84

1.67

1.6

1.5

17.97

20.25

nmol/l

0.41

143

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

300

1.76

1.66

4.7

2.5

—

(3019309) Folate [Moles/volume] in Red Blood Cells

141

1.89

1.66

2.0

1.8

1183.64

1279.50

nmol/l

0.15

102

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

655

2.51

1.59

26.0

15.1

24.08

24.72

mg/l

0.06

527

(21494755) Public health laboratory ask at order entry panel

0.00

1.58

0.0

1.7

—

(3020682) Albumin/Creatinine [Ratio] in Urine

203

1.77

1.57

5.4

3.7

20.58

8.01

mg/mmol

0.33

131

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

3.48

1.54

1.4

1.7

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

3.48

1.54

2.0

1.7

—

(3006504) Eosinophils/100 leukocytes in Blood

297

1.70

1.50

8.4

5.5

2.75

2.77

0.02

278

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

129

1.86

1.49

5.0

2.5

0.73

1.10

e6/l

—

(3019060) Gas panel - Arterial blood

2.25

1.46

5.5

3.9

—

(3002582) Erythrocytes [#/volume] in Urine

243

1.70

1.45

6.6

2.8

21.86

61.07

e6/l

1.02

172

(3011397) Hemoglobin [Presence] in Urine by Test strip

156

1.77

1.42

2.9

3.7

—

(3019069) Monocytes/100 leukocytes in Blood

300

1.68

1.42

8.6

5.9

8.71

8.49

0.26

281

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

123

1.84

1.41

5.1

2.6

3.46

2.90

e6/l

—

(3022096) Basophils/100 leukocytes in Blood

292

1.66

1.39

8.4

5.4

0.74

0.67

0.40

271

(3018095) Leukocytes [#/volume] in Urine

264

1.67

1.39

7.9

3.4

16.35

79.75

e6/l

2.30

179

(40760892) CBC W Ordered Manual Differential panel - Blood

293

1.65

1.36

8.8

5.9

—

(3018010) Neutrophils/100 leukocytes in Blood

303

1.65

1.35

8.6

5.6

58.92

57.52

0.36

286

(3044889) 12 lead EKG panel

474

1.73

1.33

5.3

3.9

—

(3030467) Casts [#/volume] in Urine by Automated count

221

1.66

1.32

4.9

2.7

0.08

0.36

e6/l

1.84

150

(3001604) Monocytes [#/volume] in Blood

315

1.63

1.29

7.9

5.3

0.58

e9/l

0.00

278

(3006315) Basophils [#/volume] in Blood

316

1.62

1.27

7.9

5.4

0.04

e9/l

0.14

279

(3002030) Lymphocytes/100 leukocytes in Blood

307

1.61

1.26

8.9

5.7

26.53

27.30

0.18

289

(40761511) CBC panel - Blood by Automated count

678

2.44

1.25

21.8

14.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

261

1.61

1.23

7.5

4.2

—

(3044640) Blood type and Crossmatch panel - Blood

207

1.63

1.21

5.1

2.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.10

1.17

1.2

2.2

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

2.60

1.17

1.6

1.3

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.11

1.16

2.9

2.7

0.74

0.72

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

390

1.59

1.16

11.6

8.6

3.97

4.34

e9/l

0.70

341

(3020891) Body temperature

2.38

1.13

6.0

4.4

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.06

1.12

2.9

2.7

1.30

1.07

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

2.47

1.10

1.2

1.3

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

136

1.63

0.99

3.7

2.9

2.48

2.47

mmol/l

0.17

120

(3002256) Pathology report gross observation

1.76

0.99

1.4

1.2

—

(4200892) Spirometry reversibility

1.86

0.98

1.9

1.3

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

275

1.49

0.92

6.8

2.9

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.96

0.90

1.9

1.6

—

(36304419) Bacteria [Presence] in Urine

213

1.49

0.85

5.4

2.7

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

684

1.88

0.79

29.6

17.9

80.97

80.27

umol/l

0.06

684

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

2.25

0.77

1.6

1.9

0.24

g/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.15

0.76

1.6

1.9

1.12

1.18

g/l

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

200

1.45

0.74

3.2

2.7

62.15

54.09

u/l

0.84

184

(3015377) Calcium [Moles/volume] in Serum or Plasma

228

1.43

0.73

5.1

3.1

2.37

2.34

mmol/l

0.77

199

(3041096) Erythrocytes [Presence] in Urine by Automated

191

1.45

0.73

9.3

3.7

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.63

0.70

4.9

3.3

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.69

0.69

1.6

1.5

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.59

0.68

11.1

5.0

1.11

1.05

mmol/l

0.35

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

654

1.62

0.68

5.9

5.2

2.42

2.68

mmol/l

1.95

593

(3026008) Bacteria identified in Urine by Culture

225

1.38

0.62

5.1

3.2

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.61

0.0

1.4

—

(3021589) Normoblasts [#/volume] in Blood

293

1.35

0.59

13.5

9.9

0.00

e9/l

0.74

240

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

611

1.49

0.58

4.9

4.2

1.33

1.27

mmol/l

0.26

551

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

210

1.35

0.55

3.1

2.9

25.27

35.44

u/l

2.13

197

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

155

1.39

0.54

2.9

2.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.56

0.52

2.1

1.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

637

1.48

0.52

5.3

4.7

6.46

6.00

mmol/l

0.67

578

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.50

0.48

3.5

1.7

—

(3022621) pH of Urine by Test strip

1.50

0.48

3.1

2.5

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

198

1.30

0.43

4.8

4.5

25.86

22.66

0.46

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

133

1.35

0.43

1.6

1.2

0.40

1.11

u/ml

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.44

0.41

3.5

1.8

—

(3022145) Colonoscopy Study observation

1.42

0.36

1.7

1.3

—

(36660697) Celiac disease serology panel - Serum

1.46

0.36

1.2

1.1

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.46

0.36

2.2

1.5

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.43

0.36

4.8

4.2

27.68

25.18

mmol/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.33

0.34

1.2

1.7

—

(3023368) Bacteria identified in Blood by Culture

205

1.25

0.33

5.3

4.7

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.30

0.31

1.4

1.5

—

(40758558) Short blood count panel - Blood

178

1.24

0.30

8.4

6.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.37

0.24

1.0

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.76

0.24

1.6

1.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

634

1.25

0.24

5.4

4.6

1.41

1.46

mmol/l

0.41

576

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.23

0.22

2.8

1.8

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.7

—

(3021788) Differential panel - Synovial fluid

0.00

0.21

0.0

1.7

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.21

0.0

2.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.2

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.21

0.0

1.1

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.21

0.0

2.0

—

(3042936) Bacteria identified in Isolate by Culture

1.25

0.21

2.5

1.7

—

(40768800) Prostate Pathology biopsy report

0.00

0.20

0.0

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.27

0.20

1.7

1.3

—

(3019225) pH of Specimen

1.17

0.19

14.5

4.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.25

0.18

8.0

7.6

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

618

1.19

0.18

24.4

14.7

78.97

77.96

ml/min/173m2

0.12

505

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.20

0.17

2.6

1.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.23

0.17

2.5

2.0

—

(3013512) EKG study

208

1.15

0.16

5.1

4.2

—

(3029937) Albumin [Presence] in Urine by Test strip

191

1.14

0.13

8.8

4.1

0.00

estimate

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

114

1.17

0.13

3.3

1.9

—

(3007164) IgA [Mass/volume] in Serum or Plasma

125

1.15

0.11

1.9

1.5

1.44

3.04

g/l

—

(40768804) Tissue Pathology biopsy report

243

1.10

0.10

3.0

2.1

—

(3000330) Specific gravity of Urine by Test strip

1.17

0.10

4.6

4.7

—

(3003694) ABO and Rh group [Type] in Blood

174

0.90

0.08

1.3

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.09

0.08

3.0

1.6

—

(3000494) Fungus identified in Specimen by Culture

1.04

0.07

3.3

1.4

—

(40768797) Stomach Pathology biopsy report

1.08

0.07

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

374

1.03

0.00

3.4

2.7

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

155

1.04

0.00

2.7

1.8

359.00

436.57

pmol/l

0.52

132

(1761868) Lipid panel - Serum or Plasma

231

0.99

0.00

3.9

3.2

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.98

0.00

4.7

2.0

267.50

405.59

nmol/l

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.5

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

1.5

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.2

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.31

—

(3036185) Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

46.20

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

2.5

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

-0.00

0.0

1.2

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.4

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.5

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.7

—

5.50

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

0.95

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.3

—

(3035062) Alkaline phosphatase.liver 1 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

121.20

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(40761536) Microorganisms panel - Urine sediment

0.86

-0.00

12.2

3.6

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

-0.00

0.0

1.1

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

-0.00

0.0

2.3

—

30.11

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.4

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.8

—

31.13

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.6

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

88.67

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.5

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

6.20

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

2.8

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

-0.00

0.0

1.8

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.1

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_RETARTOCCTRANS and mortality.

Females

Parameter	HR [95% CI]	p-value
H7_RETARTOCCTRANS	1.193 [0.88, 1.61]	0.248
Birth year	0.994 [0.99, 1.0]	0.183

During the follow-up period (1.1.1998 — 31.12.2019), 70 out of 215 females with H7_RETARTOCCTRANS died.

Males

Parameter	HR [95% CI]	p-value
H7_RETARTOCCTRANS	1.48 [1.11, 1.98]	0.008
Birth year	0.985 [0.98, 0.99]	0.002

During the follow-up period (1.1.1998 — 31.12.2019), 82 out of 228 males with H7_RETARTOCCTRANS died.

Mortality risk

Mortality risk for people of age

years, who have H7_RETARTOCCTRANS.

N-year risk	Females	Males
1	0.125%	0.28%
5	0.736%	1.675%
10	1.684%	4.116%
15	3.186%	7.73%
20	5.643%	12.837%

Relationships between endpoints

↥

Index endpoint: H7_RETARTOCCTRANS – Transient retinal artery occlusion

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Transient retinal artery occlusion

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints