Cleft hard palate NOS

Q17_CLEFT_HARD_PALATE_NOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • not Q17_CLEFT_PALATE_EXCLUDE
519188

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q35.1
  • Hospital discharge: ICD-9 7490X
  • Cause of death: ICD-10 Q35.1
  • Cause of death: ICD-9 749

2 out of 7 registries used, show all original rules.

183

4. Check minimum number of events

None

183

5. Include endpoints

None

183

6. Filter based on genotype QC (FinnGen only)

176

Control definitions (FinnGen only)

Control conditions
not Q17_CLEFT_PALATE_EXCLUDE

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2587 1496 1087
Only index persons 2115 1232 883
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.03
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 4.64 4.10 5.17
Only index persons 6.77 6.27 7.47

-FinnGen-

Key figures

All Female Male
Number of individuals 176 126 50
Unadjusted period prevalence (%) 0.04 0.04 0.02
Median age at first event (years) 15.01 16.02 12.46

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
183
Matched controls
1830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q35.1
ICD-10 Finland
Cleft hard palate
+∞
255.8
180
*
4122
FHL
Tympanostomy (tympanic tube)
23.8
72.6
58
35
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
+∞
64.5
58
*
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
16.2
55.8
54
46
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
13.5
55.2
62
67
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
19.1
50.2
43
29
4362
FHL
Nozzle reconstruction
621.5
49.9
47
*
EB1MA
NOMESCO Finland
Cephalometry with X-ray
16.7
48.7
45
35
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
+∞
48.1
44
*
SAA04
NOMESCO Finland
Special examination of mouth
12.8
47.9
54
58
SBB10
NOMESCO Finland
Dental impressions
8.6
42.5
71
125
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
10.9
36.9
45
53
4364
FHL
Pharyngeal tongue plastic
+∞
33.4
31
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
10.8
30.9
37
42
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
358.3
30.8
30
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
12.4
30.7
33
32
Q35.9
ICD-10 Finland
Cleft palate, unspecified
+∞
30.0
28
*
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
10.8
28.6
34
38
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
+∞
27.8
26
*
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
8.8
26.5
37
51
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
8.7
23.7
33
45
Q35.3
ICD-10 Finland
Cleft soft palate
+∞
23.4
22
*
Q35.71
ICD-10 Finland
Submucous cleft palate
+∞
21.3
20
*
EHC40
NOMESCO Finland
Repair of submucous cleft palate
+∞
18.0
17
*
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
8.8
17.9
24
31
Z2221
NOMESCO Finland
Medical doctor
3.8
17.5
82
320
K00.00
ICD-10 Finland
Hypodontia
20.0
15.6
23
13
4451
FHL
Guitar cutting
5.5
15.4
33
70
EBB10
NOMESCO Finland
Insertion of dental implant
49.6
15.4
18
*
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
62.0
15.1
17
*
EEC05
NOMESCO Finland
Le Fort I osteotomy
87.3
14.8
16
*
4368
FHL
Closing the fistula of the mouth
+∞
14.8
14
*
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
+∞
14.8
14
*
EHC10
NOMESCO Finland
Plastic repair of oronasal or oroantral fistula of palate
+∞
14.8
14
*
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
7.4
14.4
22
33
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
14.4
13.8
23
18
ZXD10
NOMESCO Finland
Scheduled procedure
3.3
13.7
86
392
4361
FHL
Lip plastic or reconstruction due to cleft lip
+∞
13.7
13
*
1450
FHL
Otomicroscopy
43.6
13.4
16
*
SAA03
NOMESCO Finland
Extended examination of mouth
3.3
13.4
119
662
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
5.5
13.3
28
58
EAB30
NOMESCO Finland
Correction of cleft lip
+∞
12.6
12
*
UDC00
NOMESCO Finland
Ear microscopy
5.1
12.1
28
63
ZXA10
NOMESCO Finland
Bilateral
3.6
11.9
47
159
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
5.6
11.8
24
48
ENC80
NOMESCO Finland
Plastic operation of soft palate for voice distubance
+∞
11.6
11
*
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
127.7
11.6
12
*
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
127.7
11.6
12
*
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
13.2
10.6
18
15
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
13.2
10.6
18
15
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
5.7
10.6
21
41
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
5.4
10.6
22
45
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
116.4
10.5
11
*
ZXB10
NOMESCO Finland
Medial
34.8
10.5
13
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
25.1
10.4
14
6
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.7
10.3
38
122
EBB15
NOMESCO Finland
Insertion of dental implant abutment
58.2
9.8
11
*
J01DA06
ATC
[U] cefuroxime
3.4
9.7
40
138
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
105.2
9.5
10
*
ECB17
NOMESCO Finland
Operation of gingival cleft
+∞
9.5
9
*
EHC30
NOMESCO Finland
Reconstruction of palate
+∞
9.5
9
*
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
8.2
9.2
20
27
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.5
8.5
107
657
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
94.2
8.5
9
*
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
+∞
8.4
8
*
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
18.2
8.2
12
7
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
35.1
8.2
10
*
J01DA08
ATC
[U] cefaclor
2.7
7.7
52
236
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
26.3
7.7
10
*
K07.14
ICD-10 Finland
Retrognaty, maxillary
26.3
7.7
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
7.5
66
339
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.8
7.3
17
38
Q36.9
ICD-10 Finland
Cleft lip, unilateral
+∞
7.3
7
*
4365
FHL
Correction of nasal deformity
+∞
7.3
7
*
ZSZ10
NOMESCO Finland
Secondary repair operation
+∞
7.3
7
*
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
16.6
7.3
11
7
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
4.4
7.3
19
47
DFF00
NOMESCO Finland
Pure tone audiometry
4.3
7.1
19
48
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.7
6.8
41
175
EB1WA, ,
NOMESCO Finland
23.5
6.7
9
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
6.7
80
467
4141
FHL
Myringoplasty (also for reasons other than inflammation)
72.3
6.5
7
*
SPC20
NOMESCO Finland
Implant borne crown
72.3
6.5
7
*
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
72.3
6.5
7
*
SPC30
NOMESCO Finland
Surface-retained bridge
72.3
6.5
7
*
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
3.8
6.4
20
57
UDQ12
NOMESCO Finland
Flexible laryngoscopy
5.7
6.3
17
32
EBA10
NOMESCO Finland
Operative extraction of tooth
2.4
6.3
57
294
SXC05
NOMESCO Finland
Other oral or dental procedure
3.0
6.3
30
112
7490C
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS SUBMUCOSAE]
+∞
6.3
6
*
EH1JB
NOMESCO Finland
Functional examination of palate
+∞
6.3
6
*
Q35
ICD-10 Finland
Cleft palate
+∞
6.3
6
*
7492C
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS BILATERALIS COMPLETA]
+∞
6.3
6
*
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
8.1
6.2
13
17
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
5.6
6.2
17
33
WX002
NOMESCO Finland
Sedation and analgesia
2.8
6.0
33
133

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
7
15
4.81
2.62
1.0
1.2
—
—
—
0
0
0
62
0.00
2.27
0.0
1.1
—
—
—
0
0
11
43
2.66
2.12
8.1
26.8
—
—
—
0
0
27
160
1.81
1.95
1.9
1.6
—
—
—
0
0
27
166
1.73
1.74
1.5
1.5
—
—
—
0
0
23
138
1.76
1.61
1.2
1.7
—
—
—
0
0
44
313
1.53
1.60
3.1
3.4
—
—
—
0
0
15
80
1.95
1.49
6.9
17.3
0.90
1.22
mmol/l
—
10
68
0
37
0.00
1.36
0.0
1.2
—
—
—
0
0
13
69
1.95
1.32
4.8
12.8
23.46
23.81
mmol/l
0.15
13
69
35
477
0.67
1.31
1.6
1.8
—
—
—
0
0
8
39
2.10
1.17
1.3
16.2
—
—
—
0
0
115
1021
1.34
1.10
3.9
4.0
—
—
—
0
0
101
1132
0.76
1.04
3.6
3.8
36.64
37.10
mmol/mol
0.24
94
1085
16
99
1.68
1.04
5.5
11.4
—
—
—
0
0
38
287
1.41
1.03
1.5
1.6
—
—
—
0
0
127
1378
0.74
1.02
4.0
4.5
1.78
1.74
mu/l
0.17
120
1299
150
1395
1.42
1.01
8.9
10.2
139.43
139.53
mmol/l
0.20
145
1348
16
100
1.66
1.00
7.3
11.3
105.69
104.35
mmol/l
0.63
16
100
7
37
1.93
0.95
13.1
17.7
24.50
24.70
mmol/l
—
7
37
150
1400
1.40
0.95
9.0
10.2
3.91
3.91
mmol/l
0.05
143
1347
118
1285
0.77
0.90
3.1
3.2
5.60
5.56
mmol/l
0.16
110
1200
8
42
1.95
0.90
11.8
16.3
96.65
94.07
%
—
8
42
8
43
1.90
0.88
11.8
15.9
0.68
0.69
%
—
8
43
8
44
1.85
0.87
11.8
15.6
1.00
1.48
%
—
8
44
126
1357
0.77
0.84
3.3
3.3
3.00
2.82
mmol/l
1.80
117
1292
23
165
1.45
0.83
1.9
2.3
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
82
718
1.26
0.78
4.3
4.5
0.00
0.00
estimate
-0.00
12
150
5
24
2.11
0.75
2.2
1.5
13.00
13.33
%
—
5
24
83
731
1.25
0.75
2.9
3.2
0.00
0.00
estimate
-0.00
12
143
7
39
1.83
0.73
1.1
1.2
—
—
—
0
0
12
78
1.58
0.67
3.3
5.9
—
—
—
0
0
13
87
1.53
0.65
8.5
13.4
25.05
24.81
mmol/l
0.10
13
87
81
721
1.22
0.64
2.9
3.2
0.00
0.00
estimate
-0.00
12
150
6
104
0.56
0.64
1.0
1.8
—
—
—
0
0
18
242
0.72
0.63
1.1
1.3
25.52
11.05
u/ml
—
10
100
150
1425
1.29
0.63
11.0
13.0
334.23
333.99
g/l
0.11
143
1420
13
88
1.51
0.62
11.9
14.1
—
—
—
0
0
52
443
1.24
0.62
2.0
2.1
—
—
—
0
0
48
406
1.25
0.61
11.4
8.3
0.99
1.09
inr
—
9
141
127
1346
0.82
0.58
2.9
3.1
1.42
1.47
mmol/l
0.64
118
1286
120
1278
0.82
0.57
2.8
2.9
1.29
1.19
mmol/l
0.79
109
1215
12
82
1.50
0.56
1.0
1.1
—
—
—
0
0
52
452
1.21
0.51
3.9
5.7
36.08
37.35
g/l
0.79
47
432
54
472
1.20
0.50
3.2
3.6
24.10
96.89
e6/l
0.60
35
300
41
349
1.23
0.49
2.5
2.9
—
—
—
0
0
105
975
1.18
0.49
3.5
4.1
—
363.50
—
0
10
60
671
0.84
0.47
10.0
8.3
0.00
0.00
e9/l
0.71
49
537
40
463
0.83
0.46
1.2
1.4
0.61
2.43
u/ml
—
9
108
5
31
1.63
0.43
1.8
2.4
—
—
—
0
0
129
1351
0.85
0.43
3.0
3.2
4.82
4.66
mmol/l
1.25
119
1294
80
733
1.16
0.42
4.1
5.6
6.20
6.25
mmol/l
0.07
72
641
20
248
0.78
0.42
1.1
1.3
34.82
16.36
iu/ml
—
5
76
5
33
1.53
0.41
4.0
2.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
91.83
—
0
15
0
15
0.00
0.41
0.0
2.7
—
39.77
—
0
15
0
16
0.00
0.41
0.0
3.2
—
—
—
0
0
0
16
0.00
0.41
0.0
9.8
—
48.56
—
0
16
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
5
34
1.48
0.40
1.0
1.2
—
—
—
0
0
16
124
1.32
0.40
1.6
1.3
—
—
—
0
0
38
436
0.84
0.40
2.4
2.6
—
—
—
0
0
79
854
0.87
0.39
9.2
8.8
4.09
3.98
e9/l
0.16
69
753
110
1162
0.87
0.39
3.5
4.0
13.91
14.42
pmol/l
1.67
102
1075
5
36
1.40
0.38
1.8
1.7
10.00
6.76
mmol/l
—
5
36
8
114
0.69
0.38
1.4
1.5
297.50
335.98
mu/l
—
8
104
37
424
0.84
0.38
1.3
1.5
1.78
2.21
g/l
1.50
24
267
54
595
0.87
0.34
1.9
1.8
—
—
—
0
0
39
343
1.17
0.34
3.4
2.4
42.50
37.90
ng/l
0.07
18
143
6
47
1.29
0.32
2.3
2.6
—
—
—
0
0
6
47
1.29
0.32
6.2
12.6
124.00
132.38
g/l
—
6
47
39
345
1.17
0.32
2.6
2.9
0.38
0.26
e6/l
0.41
30
251
97
1025
0.89
0.32
4.2
3.6
10.78
8.36
mm/h
0.81
91
953
8
106
0.74
0.30
1.1
1.2
—
—
—
0
0
8
107
0.74
0.30
2.6
3.3
4.82
4.86
pmol/l
—
8
97
92
972
0.89
0.29
7.0
6.1
80.84
77.53
u/l
0.25
86
912
67
720
0.89
0.28
7.9
6.0
55.44
55.17
%
0.07
61
685
68
730
0.89
0.28
8.2
6.1
30.58
30.61
%
0.01
63
698
65
697
0.90
0.26
8.2
6.2
2.62
2.74
%
0.17
60
658
65
697
0.90
0.26
8.6
6.6
8.24
7.96
%
0.31
60
663
19
161
1.20
0.25
1.1
1.2
—
—
—
0
0
27
305
0.87
0.24
1.6
2.0
198.59
404.63
u/l
0.45
22
293
69
733
0.91
0.23
7.9
6.2
0.55
0.54
e9/l
0.33
63
650
7
93
0.74
0.23
3.4
4.3
—
—
—
0
0
29
258
1.15
0.23
2.8
3.7
—
—
—
0
0
162
1590
1.16
0.22
8.5
9.0
—
—
—
0
0
8
102
0.77
0.21
3.9
4.7
1.75
1.58
%
—
8
95
72
761
0.91
0.21
7.8
6.8
0.19
0.18
e9/l
0.18
64
686
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
5.4
—
1.74
—
0
10
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
20
229
0.86
0.21
3.1
3.3
106.27
102.77
mg/l
0.01
15
155
0
12
0.00
0.21
0.0
1.0
—
1.73
—
0
12
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
64.08
—
0
13
0
13
0.00
0.21
0.0
2.1
—
45884.62
—
0
13
0
13
0.00
0.21
0.0
2.4
—
646.92
—
0
13
42
386
1.11
0.21
2.5
3.0
19.18
39.44
e6/l
0.77
32
286
63
669
0.91
0.21
8.6
6.4
0.70
0.64
%
0.49
58
627
174
1719
1.25
0.20
14.6
15.4
39.97
40.39
%
0.46
166
1639
12
144
0.82
0.20
1.1
1.5
—
—
—
0
0
6
51
1.18
0.19
1.8
2.2
—
—
—
0
0
16
185
0.85
0.19
1.4
2.4
2355.00
3737.83
u/l
—
7
83
73
767
0.92
0.19
7.5
6.1
2.10
1.97
e9/l
0.64
67
698
13
110
1.20
0.17
1.1
1.6
—
—
—
0
0
20
225
0.88
0.17
2.1
2.1
—
—
—
0
0
29
317
0.90
0.16
2.2
2.3
1.10
1.02
mg/l
0.08
20
229
15
172
0.86
0.16
2.3
2.4
13.99
14.22
umol/l
0.04
15
161
8
71
1.13
0.16
1.5
4.2
24.25
20.94
s
—
8
62
22
197
1.13
0.16
2.7
3.1
4.59
2.31
e6/l
—
10
103
70
733
0.93
0.16
7.7
6.2
0.04
0.04
e9/l
0.37
63
647
6
79
0.75
0.16
2.7
2.3
—
—
—
0
0
10
83
1.22
0.16
1.2
1.4
—
—
—
0
0
11
93
1.19
0.15
3.6
2.0
10.87
12.80
nmol/l
0.26
11
85
56
531
1.08
0.15
1.6
1.8
—
—
—
0
0
8
97
0.82
0.14
2.9
1.8
2.51
1.22
g/l
—
8
91
38
355
1.09
0.14
6.2
6.6
—
—
—
0
0
153
1506
1.10
0.14
10.1
10.2
23.15
20.79
mg/l
0.32
120
1143
31
333
0.92
0.13
1.5
1.6
—
—
—
0
0
51
536
0.93
0.12
1.8
1.8
—
—
—
0
0
11
125
0.87
0.10
1.5
1.5
—
—
—
0
0
26
242
1.09
0.10
1.3
1.3
—
—
—
0
0
15
135
1.12
0.10
1.3
1.3
—
—
—
0
0
16
145
1.11
0.09
1.4
1.4
—
—
—
0
0
5
47
1.07
0.09
1.2
1.3
—
64.00
—
0
5
5
47
1.07
0.09
1.4
1.1
—
—
—
0
0
5
48
1.04
0.09
1.0
1.3
—
—
—
0
0
16
147
1.10
0.07
1.1
1.2
—
—
—
0
0
9
87
1.04
0.07
1.2
1.1
—
—
—
0
0
10
89
1.13
0.07
2.2
2.3
—
32.65
—
0
8
11
121
0.90
0.06
1.5
1.5
—
—
—
0
0
11
121
0.90
0.06
1.5
1.5
—
—
—
0
0
12
131
0.91
0.06
2.9
2.8
—
—
—
0
0
10
110
0.90
0.05
1.4
1.5
11.55
17.19
iu/l
—
10
89
19
179
1.07
0.05
1.1
1.2
—
—
—
0
0
37
383
0.96
0.05
2.8
3.2
0.00
0.01
estimate
0.50
12
150
80
786
1.03
0.04
2.6
2.6
—
—
—
0
0
10
108
0.92
0.03
1.1
1.5
—
—
—
0
0
54
530
1.03
0.02
2.4
2.0
—
—
—
0
0
156
1551
1.04
0.02
8.3
8.0
26.01
25.66
u/l
0.08
148
1502
13
138
0.94
0.02
2.4
2.5
21.25
24.18
%
0.46
13
120
69
680
1.02
0.02
8.2
6.9
—
—
—
0
0
41
416
0.98
0.00
2.2
2.4
—
—
—
0
0
19
194
0.98
0.00
2.3
3.0
1072.89
295.42
ng/l
—
9
107
23
234
0.98
0.00
3.6
3.8
10.08
14.03
mg/mmol
0.22
16
154
16
159
1.01
0.00
1.1
1.4
—
—
—
0
0
38
384
0.99
0.00
2.6
3.1
2.35
2.35
mmol/l
0.06
31
350
12
123
0.97
0.00
1.0
1.5
—
—
—
0
0
16
157
1.02
0.00
1.1
1.5
—
—
—
0
0
16
157
1.02
0.00
1.1
1.5
—
—
—
0
0
16
157
1.02
0.00
1.1
1.5
—
—
—
0
0
48
477
1.01
0.00
7.2
8.2
1.21
1.22
mmol/l
0.16
42
443
66
657
1.01
0.00
1.8
2.2
—
—
—
0
0
24
242
0.99
0.00
5.0
2.8
—
—
—
0
0
11
115
0.95
0.00
2.7
3.0
1.45
1.45
ug/l
0.00
11
104
0
5
0.00
-0.00
0.0
1.8
—
123.64
—
0
5
8
84
0.95
-0.00
2.6
3.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
8
84
0.95
-0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
2.02
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
40
400
1.00
-0.00
1.5
1.7
91.11
97.81
pmol/l
0.62
23
211
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
-0.00
1.4
1.6
5.86
7.80
u/l
—
8
67
9
93
0.97
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
70
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.1
—
134.84
—
0
8
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
31.78
—
0
9
0
6
0.00
-0.00
0.0
9.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
16.27
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
0.15
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_CLEFT_HARD_PALATE_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_CLEFT_HARD_PALATE_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: Q17_CLEFT_HARD_PALATE_NOS – Cleft hard palate NOS

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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