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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

ICD 8 haemorrhage (epidural, subarachnoid, subduralis)

ST19_ICD8HEM

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-8 852
  • Cause of death: ICD-8 852

2 out of 7 registries used, show all original rules.

140

4. Check minimum number of events

None

140

5. Include endpoints

None

140

6. Filter based on genotype QC (FinnGen only)

140

Control definitions (FinnGen only)

Control exclude
ST19_INTRACRATRAUMA

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 140 27 113
Unadjusted period prevalence (%) 0.04 0.01 0.05
Median age at first event (years) 30.22 24.38 31.61

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
129
Matched controls
1290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
85200
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), Without mention of open intracranial wound
+∞
142.4
109
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
194.1
16.9
17
*
85290
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), Late effect
+∞
16.0
15
*
85100
ICD-8 Finland
Cerebral laceration and contusion, Without mention of open intracranial wound
+∞
16.0
15
*
85210
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), With open intracranial wound
+∞
12.7
12
*
E8879
ICD-8 Finland
Other and unspecified fall
35.8
10.5
13
*
9070A
ICD-9 Finland
Late effects of injuries to the nervous system, Late effect of intracranial injury without mention of skull fracture
+∞
9.5
9
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.4
8.8
19
26
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
10.0
8.3
16
18
S06.0
ICD-10 Finland
Concussion
16.4
7.9
12
8
E8190
ICD-8 Finland
Motor vehicle traffic accident of unspecified nature, Driver of motor vehicle other than motorcycle
19.8
7.7
11
6
85000
ICD-8 Finland
Concussion, Current or unspecified
+∞
7.4
7
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
73.3
6.5
7
*

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_ICD8HEM – ICD 8 haemorrhage (epidural, subarachnoid, subduralis)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).