info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

ICD 8 haemorrhage (epidural, subarachnoid, subduralis)

ST19_ICD8HEM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-8 852
  • Cause of death: ICD-8 852

2 out of 7 registries used, show all original rules.

140

4. Check minimum number of events

None

140

5. Include endpoints

None

140

6. Filter based on genotype QC (FinnGen only)

136

Control definitions (FinnGen only)

Control exclude
ST19_INTRACRATRAUMA

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 136 26 110
Unadjusted period prevalence (%) 0.04 0.01 0.05
Median age at first event (years) 29.92 24.32 31.25

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
140
Matched controls
1400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
85200
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), Without mention of open intracranial wound
+∞
154.1
118
*
85290
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), Late effect
+∞
19.2
18
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
204.9
18.0
18
*
85100
ICD-8 Finland
Cerebral laceration and contusion, Without mention of open intracranial wound
+∞
15.9
15
*
85210
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), With open intracranial wound
+∞
13.8
13
*
S06.0
ICD-10 Finland
Concussion
30.8
11.0
14
5
E8879
ICD-8 Finland
Other and unspecified fall
35.5
10.5
13
*
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
10.7
9.6
18
19
85000
ICD-8 Finland
Concussion, Current or unspecified
+∞
9.5
9
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
9.5
9
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.0
9.5
21
30
9070A
ICD-9 Finland
Late effects of injuries to the nervous system, Late effect of intracranial injury without mention of skull fracture
95.6
8.5
9
*
W19
ICD-10 Finland
Unspecified fall
4.7
8.0
20
48
E8190
ICD-8 Finland
Motor vehicle traffic accident of unspecified nature, Driver of motor vehicle other than motorcycle
16.9
7.4
11
7
80000
ICD-8 Finland
Fracture of vault of skull, Closed
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
52
686
0.62
2.02
6.2
4.7
2.22
2.01
ug/l
0.18
46
604
33
479
0.59
1.85
7.1
5.6
2.38
2.86
%
0.71
33
451
32
466
0.59
1.81
6.6
5.5
0.61
0.65
%
0.17
32
439
26
396
0.58
1.74
3.4
2.9
0.80
0.69
ug/l
0.27
19
242
74
887
0.65
1.73
16.3
17.9
15.46
15.06
%
0.22
74
869
0
49
0.00
1.72
0.0
1.5
—
—
—
0
0
36
486
0.65
1.40
6.2
5.5
61.45
57.88
%
1.23
36
462
94
1052
0.68
1.31
4.8
5.2
2.68
2.64
mmol/l
0.14
86
964
36
480
0.66
1.30
7.1
5.9
8.47
8.97
%
0.39
36
454
37
490
0.67
1.29
6.4
5.7
24.81
26.71
%
0.51
37
463
10
49
2.12
1.25
1.0
1.1
—
—
—
0
0
5
112
0.43
1.19
1.4
1.3
—
—
—
0
0
15
88
1.79
1.17
2.5
6.7
—
—
—
0
0
64
757
0.72
1.14
5.3
4.0
13.91
12.30
mm/h
0.26
58
700
89
995
0.71
1.10
5.8
6.3
40.90
40.82
mmol/mol
0.02
78
929
28
381
0.67
1.09
4.4
3.6
22.56
112.87
e6/l
0.69
23
278
38
483
0.71
1.01
6.8
6.1
—
—
—
0
0
90
997
0.73
0.98
3.9
4.1
1.36
1.31
mmol/l
0.30
79
905
81
911
0.74
0.97
3.8
4.0
1.96
1.98
mu/l
0.09
74
806
6
27
2.28
0.94
1.5
1.6
—
—
—
0
0
93
1023
0.73
0.94
4.2
4.6
1.33
1.37
mmol/l
0.51
83
933
7
129
0.52
0.93
2.1
2.4
1.67
1.75
%
—
7
117
67
772
0.75
0.93
3.5
4.1
—
—
—
0
0
33
250
1.42
0.92
1.2
1.3
—
—
—
0
0
60
701
0.75
0.91
3.0
3.3
14.93
14.88
pmol/l
0.05
51
619
8
46
1.78
0.84
6.3
4.5
—
—
—
0
0
94
1026
0.74
0.84
4.3
4.7
4.47
4.46
mmol/l
0.02
84
951
99
1072
0.74
0.83
14.8
14.3
—
—
—
0
0
60
695
0.76
0.83
4.0
3.8
—
—
—
0
0
0
25
0.00
0.80
0.0
2.6
—
127.47
—
0
17
5
23
2.22
0.77
1.2
1.1
—
—
—
0
0
95
1027
0.77
0.71
16.7
15.0
36.25
24.82
mg/l
1.80
80
830
5
92
0.53
0.70
1.2
1.4
—
—
—
0
0
12
78
1.59
0.68
3.8
3.5
—
—
—
0
0
57
492
1.27
0.65
4.7
6.6
1.20
1.20
mmol/l
0.00
47
419
108
1144
0.76
0.64
22.0
21.8
40.60
40.81
%
0.14
98
1063
30
369
0.76
0.61
2.5
3.0
—
—
—
0
0
0
21
0.00
0.60
0.0
3.0
—
16.12
—
0
11
0
22
0.00
0.60
0.0
4.1
—
40.30
—
0
15
8
53
1.54
0.59
1.1
1.2
—
—
—
0
0
11
75
1.51
0.52
8.9
7.9
25.17
24.38
mmol/l
0.25
11
70
40
345
1.22
0.45
2.9
3.0
7.62
8.17
mmol/l
0.41
35
286
6
95
0.62
0.43
2.3
2.9
64.03
65.90
g/l
—
6
84
0
15
0.00
0.41
0.0
1.7
—
4.54
—
0
7
15
115
1.34
0.41
5.1
7.2
95.53
95.48
%
0.01
15
110
5
34
1.49
0.41
1.2
1.1
—
—
—
0
0
5
34
1.49
0.41
1.6
1.7
—
—
—
0
0
14
178
0.76
0.37
1.1
1.3
2.69
2.67
g/l
—
7
105
25
294
0.82
0.35
4.1
2.9
—
—
—
0
0
38
334
1.19
0.35
2.6
3.1
70.42
241.62
mg/l
0.47
28
232
6
87
0.68
0.34
1.8
1.4
—
—
—
0
0
96
1007
0.85
0.34
4.4
4.9
6.30
6.12
mmol/l
0.48
85
923
6
89
0.66
0.34
1.2
1.3
—
—
—
0
0
106
1102
0.84
0.32
18.4
17.9
76.99
85.08
umol/l
3.12
106
1102
7
98
0.70
0.32
1.6
1.4
—
—
—
0
0
7
100
0.68
0.32
1.1
1.7
—
—
—
0
0
29
332
0.84
0.31
3.0
4.1
—
—
—
0
0
50
455
1.15
0.30
4.6
5.6
1.20
1.21
mmol/l
0.04
45
412
16
130
1.26
0.30
4.9
6.7
5.43
5.01
kpa
0.75
16
121
16
130
1.26
0.30
4.9
6.6
13.55
11.65
kpa
0.54
16
123
7
57
1.24
0.29
1.3
2.5
0.67
0.69
%
—
7
57
16
131
1.25
0.28
4.9
6.7
2.33
1.34
mmol/l
0.55
11
103
36
323
1.15
0.26
3.4
4.4
—
—
—
0
0
44
480
0.88
0.25
4.7
5.0
0.00
0.00
estimate
—
10
84
45
489
0.88
0.24
4.3
3.7
0.00
0.00
estimate
—
9
80
15
125
1.22
0.23
1.2
1.4
—
—
—
0
0
43
394
1.13
0.23
1.8
2.1
—
—
—
0
0
24
271
0.86
0.22
3.5
3.5
—
—
—
0
0
5
41
1.23
0.22
16.2
13.3
—
—
—
0
0
8
102
0.77
0.22
1.1
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
5.3
—
87.64
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
0.99
—
0
10
0
10
0.00
0.21
0.0
1.0
—
13.50
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
67
634
1.11
0.21
4.5
4.6
7.10
6.92
mmol/l
0.19
62
596
0
13
0.00
0.21
0.0
3.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
91.89
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
48
1.26
0.20
2.2
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
11
90
1.24
0.20
1.5
1.5
—
—
—
0
0
7
58
1.22
0.18
1.3
2.6
1.17
1.49
%
—
7
58
7
60
1.18
0.18
1.6
2.7
—
—
—
0
0
45
480
0.91
0.17
4.2
3.7
0.00
0.01
estimate
—
10
90
83
859
0.92
0.16
20.0
18.9
332.12
333.72
g/l
0.77
83
854
9
80
1.13
0.15
6.4
4.3
—
—
—
0
0
20
222
0.88
0.15
3.8
3.0
591.80
584.20
mosm/kgh2o
0.05
15
191
16
141
1.15
0.14
4.6
6.3
104.06
103.77
mmol/l
0.13
16
141
18
201
0.88
0.14
1.5
1.6
1713.57
1211.11
nmol/l
0.60
13
152
11
128
0.85
0.14
1.5
1.3
—
—
—
0
0
9
106
0.84
0.13
1.9
1.6
—
—
—
0
0
11
127
0.85
0.13
1.3
1.9
—
—
—
0
0
38
358
1.08
0.12
3.1
3.6
13.57
9.36
mg/mmol
0.20
28
243
6
55
1.09
0.09
2.8
6.6
26.10
24.25
mmol/l
—
6
55
17
184
0.91
0.08
1.0
1.2
0.90
0.94
u/ml
—
5
43
8
78
1.03
0.07
1.8
2.9
—
7.42
—
0
8
7
81
0.86
0.07
2.9
2.4
—
—
—
0
0
9
86
1.05
0.07
5.3
4.5
—
—
—
0
0
42
434
0.95
0.05
3.3
4.0
42.92
52.80
ng/l
0.23
30
319
63
643
0.96
0.04
4.5
4.1
—
5013.67
—
0
12
32
329
0.96
0.02
2.2
2.3
—
—
—
0
0
24
247
0.97
0.01
5.6
4.0
0.00
0.00
estimate
—
10
78
13
124
1.05
0.00
1.5
1.3
—
—
—
0
0
21
216
0.97
0.00
4.3
3.6
—
—
—
0
0
27
274
0.98
0.00
3.4
3.0
—
—
—
0
0
24
239
1.01
0.00
3.7
6.7
—
—
—
0
0
16
157
1.02
0.00
1.2
1.9
—
—
—
0
0
54
535
1.02
0.00
14.0
15.5
1.55
1.30
inr
0.55
13
153
10
98
1.02
0.00
3.6
4.0
—
—
—
0
0
27
270
1.00
-0.00
1.4
1.7
1.56
1.38
mmol/l
0.48
21
228
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
11.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
13.8
—
1261.11
—
0
9
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
99
0.90
-0.00
6.8
6.6
10.83
10.55
mmol/l
—
9
92
0
5
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.6
—
914.22
—
0
9
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
31.89
—
0
9
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.8
—
—
—
0
0
42
420
1.00
-0.00
1.7
1.9
81.30
91.20
pmol/l
0.75
25
226
0
7
0.00
-0.00
0.0
5.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
1.51
—
0
9
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
17.40
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
156.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.55
—
0
5
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_ICD8HEM – ICD 8 haemorrhage (epidural, subarachnoid, subduralis)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).