eyelid disease: A disease involving the eyelid.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
518 |
4. Check minimum number of eventsNone |
518 |
5. Include endpointsNone |
518 |
6. Filter based on genotype QC (FinnGen only) |
502 |
Control definitions (FinnGen only)
- Control exclude
- H7_LIDLACRIMALORBIT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified and unspecified disorders of eyelid
based on the number of shared cases.
Similar with more cases:
- Other disorders of eyelid
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3094 | 1699 | 1382 |
| Only index persons | 2849 | 1573 | 1276 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.04 |
| Only index persons | 0.05 | 0.06 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 56.11 | 57.78 | 54.14 |
| Only index persons | 56.64 | 58.19 | 54.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 502 | 286 | 216 |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | 0.10 |
| Median age at first event (years) | 62.80 | 61.65 | 64.31 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 518
- Matched controls
- 5180
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02.8
ICD-10 Finland
Other specified disorders of eyelid
+∞
307.7
322
*
H02.9
ICD-10 Finland
Disorder of eyelid, unspecified
3063.7
207.9
187
*
H02.3
ICD-10 Finland
Blepharochalasis
160.1
110.1
113
9
CBB30
NOMESCO Finland
Excision of lesion of eyelid
17.0
76.4
66
44
H02.4
ICD-10 Finland
Ptosis of eyelid
119.2
67.8
72
7
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
+∞
49.8
47
*
H04.10
ICD-10 Finland
Dry eye syndrome
6.4
47.7
88
161
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
47.6
45
*
H00.1
ICD-10 Finland
Chalazion
11.6
40.5
43
40
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
417.6
39.6
39
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
359.6
34.3
34
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.0
33.2
289
1532
CBA10
NOMESCO Finland
Biopsy of eyelid
31.4
28.9
38
13
H01.0
ICD-10 Finland
Blepharitis
6.2
28.6
51
89
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
296.7
28.0
28
*
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
+∞
23.1
22
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.8
21.1
133
570
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
5.7
19.3
37
69
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
18.9
18
*
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
+∞
16.8
16
*
F29
ICPC
Eye symptom/complaint other
3.2
16.4
73
256
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
15.7
15
*
CBB00
NOMESCO Finland
Excision of chalazion
87.8
15.7
17
*
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
14.6
14
*
ZXA05
NOMESCO Finland
Left side
2.2
14.4
159
864
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
23.0
14.3
20
9
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
77.2
13.6
15
*
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
77.2
13.6
15
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.1
13.6
198
1192
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
13.6
13
*
H02.1
ICD-10 Finland
Ectropion of eyelid
143.6
13.5
14
*
WX110
NOMESCO Finland
Infiltration anesthesia
2.2
13.5
376
2858
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
+∞
12.5
12
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
12.5
12
*
ZXA10
NOMESCO Finland
Bilateral
2.3
12.2
112
561
WX002
NOMESCO Finland
Sedation and analgesia
2.2
11.8
116
596
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
23.5
11.6
16
7
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.6
11.5
39
115
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
11.4
115
596
M79.6
ICD-10 Finland
Pain in limb
1.9
11.4
234
1565
E0000UV, ,
ATC
1.9
11.4
224
1477
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
4.7
11.3
26
57
L17
ICPC
Foot/toe symptom/complaint
2.0
11.1
170
1030
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.6
11.0
67
277
H02AB06
ATC
prednisolone; systemic
1.9
10.8
257
1791
R51.80
ICD-10 Finland
Headache
2.3
10.6
89
427
CBN20
NOMESCO Finland
Shortening of eyelid retractors
+∞
10.4
10
*
QAJ10
NOMESCO Finland
Browlift
+∞
10.4
10
*
H00.00
ICD-10 Finland
Hordeolum
4.1
10.4
29
74
CD2S4
NOMESCO Finland
Photography of eye
16.5
10.4
16
10
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.4
10.3
79
365
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
10.0
131
748
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
9.9
163
1004
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
10.9
9.8
18
17
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.7
9.5
54
216
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.5
9.4
62
266
3748X
ICD-9 Finland
Other disorders of eyelids, Other disorders of eyelid
+∞
9.4
9
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.1
9.4
108
587
XCK00
NOMESCO Finland
Perimetry
3.1
9.2
40
138
CFA20
NOMESCO Finland
Biopsy of conjunctiva
37.4
9.0
11
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
8.8
365
2932
M25.5
ICD-10 Finland
Pain in joint
1.8
8.8
171
1104
S18
ICPC
Laceration/cut
1.7
8.7
249
1796
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
50.9
8.7
10
*
J05AB11
ATC
valaciclovir; oral
2.1
8.5
88
459
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
8.5
173
1132
ZXA00
NOMESCO Finland
Right side
1.8
8.4
147
918
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
8.4
8
*
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
8.4
8
*
A02BC05
ATC
esomeprazole; systemic
1.7
8.2
214
1498
F16
ICPC
Eyelid symptom/complaint
3.4
8.2
30
93
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
8.1
200
1378
A02BC02
ATC
pantoprazole; systemic
1.8
8.1
352
2831
CBB50
NOMESCO Finland
Excision of lesion of eyelid and reconstruction using graft or flap
22.4
8.0
11
5
N02AX02
ATC
tramadol; systemic, rectal
1.7
8.0
231
1659
R60.0
ICD-10 Finland
Localized oedema
2.2
8.0
75
375
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
8.0
49
203
UJF32
NOMESCO Finland
Coloscopy
1.8
8.0
145
913
N02BE01
ATC
paracetamol; systemic, rectal
2.3
7.9
465
4101
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
7.9
100
560
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
7.8
146
926
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.9
7.8
38
140
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
7.8
82
430
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
7.6
245
1804
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
7.6
66
320
Z71.8
ICD-10 Finland
Other specified counselling
1.8
7.6
157
1026
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
4.0
7.5
21
54
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
8.5
7.4
15
18
H062, E050,
ICD-10 Finland
+∞
7.3
7
*
S01XA18
ATC
ciclosporin; ophthalmic
+∞
7.3
7
*
CBB12
NOMESCO Finland
Resection of lax skin in lower eyelid
+∞
7.3
7
*
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
+∞
7.3
7
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
7.3
7
*
H01
ICPC
Ear pain/earache
2.2
7.2
61
293
SAA02
NOMESCO Finland
Basic examination of mouth
1.7
7.1
326
2616
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.3
7.0
52
236
N03AX16
ATC
[U] pregabalin
1.8
6.9
126
791
J31.0
ICD-10 Finland
Chronic rhinitis
2.4
6.9
48
212
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.5
6.9
45
193
Z01.2
ICD-10 Finland
Dental examination
1.6
6.9
221
1617
M03BX02
ATC
tizanidine; oral
1.6
6.8
309
2457
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
6.8
56
266
H10
ICD-10 Finland
Conjunctivitis
2.6
6.8
39
157
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
17.0
6.8
10
6
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
6.8
181
1262
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
22.9
6.7
9
*
N05CF01
ATC
zopiclone; oral
1.7
6.7
172
1187
L82
ICD-10 Finland
Seborrhoeic keratosis
1.9
6.6
100
591
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
6.6
98
577
R06AE07
ATC
cetirizine; oral
1.6
6.5
209
1524
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
70.7
6.4
7
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
14.5
6.4
10
7
M54.5
ICD-10 Finland
Low back pain
1.6
6.4
179
1259
M48.0
ICD-10 Finland
Spinal stenosis
2.0
6.4
73
393
SFA00
NOMESCO Finland
Small restoration
2.0
6.3
72
387
H02.2
ICD-10 Finland
Lagophthalmos
+∞
6.3
6
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
6.3
6
*
CBG10
NOMESCO Finland
Cryotherapy for trichiasis
+∞
6.3
6
*
TCB10
NOMESCO Finland
Simple epilation of cilia
+∞
6.3
6
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.2
6.2
24
77
G51.0
ICD-10 Finland
Bell palsy
5.1
6.2
18
36
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
6.2
136
896
ZXE00
NOMESCO Finland
One hour or less
1.6
6.2
191
1374
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
6.2
317
2571
C08CA01
ATC
amlodipine; oral
1.6
6.1
199
1450
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.1
174
1228
P01AB01
ATC
metronidazole; oral, rectal
1.6
6.1
203
1488
H26.4
ICD-10 Finland
After-cataract
2.2
6.0
51
245
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
101
4.21
14.61
3.5
1.5
5.92
6.74
iu/l
0.12
18
29
296
2124
1.92
11.71
6.3
7.1
1.21
1.21
mmol/l
0.03
266
1822
330
2468
1.93
11.36
10.2
9.3
4.09
4.11
e9/l
0.06
291
2179
489
4278
3.56
11.20
16.7
14.1
20.65
23.99
mg/l
1.73
410
3361
260
1824
1.85
10.69
5.3
4.8
36.18
35.38
g/l
1.57
243
1707
393
3170
1.99
10.18
4.3
4.1
11.62
12.35
mm/h
0.52
367
2915
248
1744
1.81
9.86
2.0
2.0
97.03
94.52
pmol/l
0.37
124
892
134
780
1.97
9.61
3.7
4.0
31.22
472.54
ng/l
4.31
104
622
269
1950
1.79
9.56
5.9
6.1
1.21
1.21
mmol/l
0.17
255
1770
127
740
1.95
9.02
2.7
2.7
1.07
1.14
e6/l
0.07
71
421
281
2089
1.75
8.92
4.7
3.6
0.00
0.01
estimate
0.50
33
380
278
2067
1.74
8.77
5.8
4.8
0.00
0.00
estimate
-0.00
38
388
274
2069
1.69
7.84
4.6
3.6
0.00
0.00
estimate
0.50
43
422
321
2536
1.70
7.67
4.8
4.9
6.45
6.77
mmol/l
2.79
303
2377
166
1099
1.75
7.67
2.8
2.7
9370.08
8094.77
umol/l
0.10
148
964
451
3944
2.11
7.65
5.6
4.6
1.85
2.24
mu/l
0.67
419
3560
389
3244
1.80
7.62
4.7
3.8
14.85
14.86
pmol/l
0.04
362
2918
68
338
2.16
7.37
2.7
2.6
60.33
66.42
ml/min/173m2
0.64
33
133
264
2000
1.65
7.25
6.6
5.5
55.74
57.44
%
1.58
250
1883
125
785
1.78
6.83
2.7
3.4
2.44
2.45
mmol/l
0.31
110
687
264
2026
1.62
6.70
6.9
5.8
28.67
27.54
%
0.95
250
1904
395
3357
1.74
6.68
8.5
7.5
75.85
79.22
u/l
1.19
380
3130
468
4212
2.15
6.37
5.5
4.6
5.91
6.00
mmol/l
0.96
435
3815
235
1770
1.60
6.33
3.0
2.6
96.57
141.32
ug/l
4.19
221
1623
497
4595
3.01
6.29
12.7
10.4
25.71
26.30
u/l
0.38
492
4417
289
2292
1.59
6.21
6.3
6.4
10.66
11.31
umol/l
0.68
277
2179
94
558
1.84
6.14
5.3
7.2
104.27
104.30
mmol/l
0.02
94
558
170
1198
1.62
5.95
3.2
3.0
0.17
0.41
e6/l
3.14
123
903
87
515
1.83
5.72
5.7
9.0
1.25
1.22
mmol/l
0.02
70
406
506
4756
3.76
5.59
26.7
20.9
248.44
248.06
e9/l
0.05
500
4627
506
4758
3.74
5.55
26.8
20.9
4.48
4.49
e12/l
0.17
495
4619
139
947
1.64
5.51
1.7
1.6
1.06
1.24
mg/l
0.46
114
740
192
1414
1.57
5.50
3.5
3.2
28.52
32.84
u/l
1.77
187
1347
469
4268
2.05
5.50
5.3
4.5
4.68
4.67
mmol/l
0.11
442
3927
484
4459
2.30
5.46
20.6
16.7
3.97
3.98
mmol/l
0.11
478
4325
206
1544
1.55
5.45
4.1
3.1
—
—
—
0
0
483
4448
2.27
5.42
20.4
16.6
139.53
139.73
mmol/l
0.93
477
4316
107
684
1.71
5.40
3.1
2.9
1.98
2.30
e6/l
0.16
52
370
455
4105
1.89
5.39
4.4
4.1
1.37
1.30
mmol/l
1.19
422
3729
475
4350
2.11
5.35
6.0
5.0
2.77
2.75
mmol/l
0.11
446
3977
466
4242
1.98
5.29
4.9
4.5
1.45
1.47
mmol/l
0.73
438
3880
505
4755
3.47
5.28
26.6
21.1
39.84
40.24
%
0.61
467
4440
15
40
3.83
5.12
1.3
1.2
—
—
—
0
0
194
1452
1.54
5.09
3.1
3.7
2.35
2.35
mmol/l
0.03
179
1262
12
20
6.11
4.94
2.0
2.3
—
—
—
0
0
221
1717
1.50
4.79
2.5
2.3
76.32
76.78
nmol/l
0.08
207
1516
182
1366
1.51
4.62
3.1
3.1
7.07
7.46
mmol/l
0.64
160
1143
11
19
5.89
4.46
1.3
4.4
675.91
855.11
u/ml
0.21
11
19
443
4026
1.69
4.31
6.6
5.9
39.87
40.15
mmol/mol
0.28
419
3721
179
1360
1.48
4.21
3.7
3.9
11.97
7.31
mg/mmol
0.68
114
851
68
411
1.75
4.16
2.8
3.4
2.13
2.00
mmol/l
0.11
54
333
59
345
1.80
4.03
3.0
3.1
187.06
186.99
ng/l
0.00
54
315
176
1345
1.47
3.98
2.4
2.0
222.78
266.81
u/l
0.23
163
1262
129
927
1.52
3.94
6.1
4.0
1.01
1.02
kg/l
—
8
111
140
1027
1.50
3.87
2.4
2.1
2.72
3.16
mg/l
1.08
124
880
142
1045
1.49
3.86
1.5
1.5
23.55
20.83
nmol/l
0.37
128
872
250
2054
1.42
3.77
16.8
14.5
1.21
1.27
inr
0.35
63
585
244
1997
1.42
3.76
2.6
2.6
—
—
—
0
0
64
392
1.72
3.74
2.4
2.3
32.98
31.61
u/l
0.15
57
329
74
477
1.64
3.58
1.6
1.8
—
—
—
0
0
152
1152
1.45
3.52
1.7
1.6
1.45
1.37
mmol/l
0.45
131
948
292
2484
1.40
3.51
3.0
2.8
—
—
—
0
0
61
377
1.70
3.46
3.1
2.4
4.51
8.00
ug/l
1.46
55
338
168
1312
1.42
3.27
3.5
3.1
19.49
65.86
e6/l
2.30
120
1015
87
601
1.54
3.15
2.0
2.3
2.35
2.34
g/l
0.11
81
552
173
1366
1.40
3.14
2.9
2.4
61.39
114.82
u/l
0.44
164
1267
72
477
1.59
3.13
1.7
1.9
—
—
—
0
0
164
1286
1.40
3.10
2.7
3.1
727.59
1306.93
ng/l
4.66
139
1101
82
566
1.53
2.98
2.1
2.4
20.66
22.06
%
0.51
65
484
89
632
1.49
2.83
1.5
1.4
—
—
—
0
0
35
587
0.57
2.73
4.9
4.6
29.96
32.41
%
0.58
26
388
6
10
6.05
2.70
1.0
1.9
—
—
—
0
0
96
702
1.45
2.64
2.9
3.4
0.81
0.81
mmol/l
0.02
91
661
91
664
1.45
2.53
2.1
2.3
13.16
12.81
umol/l
0.18
86
618
117
897
1.39
2.47
2.5
2.5
4.85
5.84
e6/l
0.27
102
817
52
340
1.59
2.41
3.4
3.4
75.80
82.30
ng/l
0.20
45
303
89
654
1.44
2.38
1.7
1.8
28.85
29.66
s
1.05
83
636
34
199
1.76
2.38
2.1
3.1
23.86
23.99
mmol/l
0.09
34
192
37
224
1.70
2.31
3.5
2.4
0.65
0.66
%
0.05
37
224
200
1681
1.31
2.28
4.0
3.6
261.02
42.19
ng/l
0.51
136
1207
26
142
1.87
2.27
1.5
1.7
—
145.71
—
0
7
11
41
2.72
2.22
2.0
2.0
—
—
—
0
0
192
1629
1.28
1.99
5.3
3.8
—
—
—
0
0
101
784
1.36
1.97
1.5
1.7
1084.75
1202.42
nmol/l
0.63
85
593
13
59
2.23
1.85
1.2
1.1
—
—
—
0
0
7
23
3.07
1.80
1.0
1.0
—
—
—
0
0
92
714
1.35
1.80
1.3
1.3
18.63
36.20
iu/ml
2.24
29
219
27
162
1.70
1.78
1.5
2.6
—
—
—
0
0
18
95
1.93
1.77
1.1
1.3
—
—
—
0
0
434
4105
1.35
1.77
14.6
13.1
79.18
79.75
ml/min/173m2
0.22
376
3379
86
670
1.34
1.64
1.2
1.3
1.21
11.63
u/ml
3.71
28
271
65
485
1.39
1.63
3.0
2.4
4.40
8.46
umol/l
4.91
58
420
15
77
1.98
1.60
1.7
1.4
—
—
—
0
0
15
77
1.98
1.60
1.7
1.4
—
—
—
0
0
10
43
2.35
1.59
3.4
2.4
—
—
—
0
0
18
99
1.85
1.59
1.2
1.2
—
—
—
0
0
18
100
1.83
1.55
1.1
1.1
—
—
—
0
0
45
318
1.45
1.52
2.1
2.2
11.50
13.01
nmol/l
0.69
38
291
21
124
1.72
1.49
1.1
1.2
—
—
—
0
0
21
124
1.72
1.49
1.1
1.2
—
—
—
0
0
9
37
2.46
1.48
3.9
2.6
—
—
—
0
0
21
125
1.71
1.46
2.0
1.7
37.43
41.66
nmol/l
0.41
21
119
135
1136
1.25
1.45
5.0
4.3
22.90
21.37
%
0.40
66
540
41
288
1.46
1.44
1.6
1.6
—
—
—
0
0
165
1422
1.24
1.42
5.1
5.0
1.74
2.81
ug/l
2.32
151
1260
25
159
1.60
1.37
1.3
2.1
4.01
2.98
mg/l
0.46
20
120
111
919
1.26
1.36
1.3
1.2
1.19
2.10
u/ml
0.66
22
253
10
47
2.15
1.34
1.8
1.8
—
—
—
0
0
10
47
2.15
1.34
1.9
2.0
—
—
—
0
0
10
47
2.15
1.34
1.8
1.8
—
—
—
0
0
10
47
2.15
1.34
1.8
1.8
—
—
—
0
0
6
24
2.52
1.30
1.3
1.4
—
—
—
0
0
25
163
1.56
1.25
2.8
1.7
—
—
—
0
0
12
63
1.93
1.23
1.2
1.2
1.00
12.04
u/ml
—
5
27
6
26
2.32
1.19
2.3
2.1
—
—
—
0
0
6
26
2.32
1.19
2.3
2.1
—
—
—
0
0
10
50
2.02
1.17
1.2
1.5
0.17
0.28
nmol/l
—
10
39
84
686
1.27
1.16
1.9
1.9
—
—
—
0
0
13
72
1.83
1.16
1.4
1.3
—
—
—
0
0
5
20
2.51
1.15
2.6
2.4
—
—
—
0
0
5
20
2.51
1.15
2.6
2.4
—
—
—
0
0
134
1154
1.22
1.15
6.3
3.9
0.00
0.00
estimate
-0.00
34
385
63
497
1.30
1.14
1.8
1.7
1.46
1.47
%
0.02
56
443
19
120
1.61
1.10
1.1
1.2
—
—
—
0
0
5
21
2.39
1.09
2.6
2.3
—
—
—
0
0
10
52
1.94
1.06
1.9
1.9
—
—
—
0
0
73
600
1.25
0.97
1.5
1.4
—
—
—
0
0
15
93
1.63
0.94
2.8
1.7
216.47
215.88
pmol/l
0.01
15
86
302
2827
1.16
0.94
3.5
3.0
46.91
51.57
u/l
0.61
282
2624
19
126
1.53
0.92
1.4
1.5
—
—
—
0
0
108
934
1.20
0.89
1.4
1.7
466.99
22280896.41
pmol/l
1.04
94
763
6
29
2.08
0.89
1.3
1.0
—
—
—
0
0
8
42
1.92
0.89
4.1
3.8
—
—
—
0
0
6
30
2.01
0.87
14.2
16.3
1218.50
1597.07
nmol/l
—
6
30
6
30
2.01
0.87
1.0
1.3
—
—
—
0
0
6
31
1.95
0.84
1.5
1.2
—
—
—
0
0
6
31
1.95
0.84
1.0
1.3
—
—
—
0
0
20
138
1.47
0.83
2.8
2.9
—
—
—
0
0
12
73
1.66
0.82
2.0
1.8
—
—
—
0
0
12
73
1.66
0.82
2.0
1.8
—
—
—
0
0
8
47
1.71
0.81
1.3
1.6
—
—
—
0
0
8
47
1.71
0.81
1.3
1.6
—
—
—
0
0
44
350
1.28
0.79
2.2
1.9
—
—
—
0
0
27
200
1.37
0.78
1.4
1.3
—
—
—
0
0
69
580
1.22
0.77
12.1
7.2
—
—
—
0
0
12
75
1.61
0.75
1.8
1.8
—
—
—
0
0
5
24
2.09
0.74
1.4
1.8
—
—
—
0
0
10
60
1.68
0.72
3.3
2.6
—
899.13
—
0
8
20
144
1.40
0.69
1.2
2.2
—
—
—
0
0
10
61
1.65
0.69
1.5
1.5
—
—
—
0
0
10
156
0.63
0.68
2.2
1.8
—
—
—
0
0
18
128
1.42
0.66
1.4
1.6
0.00
0.10
iu/ml
—
6
27
10
62
1.62
0.65
1.1
2.6
107.40
105.50
mmol/l
—
10
62
7
44
1.60
0.65
2.1
1.3
—
—
—
0
0
32
252
1.29
0.64
1.6
1.7
—
—
—
0
0
5
29
1.73
0.64
1.4
1.3
—
—
—
0
0
5
29
1.73
0.64
1.4
1.3
—
—
—
0
0
5
30
1.67
0.61
6.6
3.7
61.00
96.20
nmol/l
—
5
30
13
88
1.49
0.61
2.2
1.5
—
—
—
0
0
39
318
1.24
0.60
2.1
1.8
—
—
—
0
0
18
131
1.39
0.60
2.8
1.6
—
—
—
0
0
6
36
1.67
0.57
1.3
1.2
—
—
—
0
0
6
37
1.63
0.55
1.3
1.1
—
—
—
0
0
16
116
1.39
0.55
2.1
1.6
—
—
—
0
0
6
39
1.54
0.53
1.3
1.1
—
—
—
0
0
16
118
1.37
0.50
1.6
1.4
—
—
—
0
0
6
41
1.47
0.50
1.0
1.1
—
—
—
0
0
6
41
1.47
0.50
2.3
1.6
—
—
—
0
0
16
119
1.36
0.48
1.4
1.4
246.10
288.87
ug/g
—
10
68
55
478
1.17
0.47
4.1
4.4
3.46
33.15
ug/l
1.14
46
402
14
103
1.37
0.45
1.9
1.8
—
—
—
0
0
113
1039
1.11
0.43
2.2
2.3
—
—
—
0
0
5
31
1.62
0.43
1.6
1.2
—
—
—
0
0
5
31
1.62
0.43
1.2
1.0
—
—
—
0
0
5
31
1.62
0.43
1.8
2.0
—
—
—
0
0
8
57
1.41
0.42
1.5
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
2.19
—
0
7
12
88
1.37
0.40
3.2
4.3
29.33
24.08
mg/l
—
6
60
13
97
1.35
0.40
2.2
1.8
—
—
—
0
0
14
106
1.33
0.39
1.6
1.4
—
—
—
0
0
90
822
1.11
0.39
2.7
2.9
0.59
0.80
ug/l
1.73
64
522
13
169
0.76
0.37
2.8
2.0
—
—
—
0
0
23
275
0.83
0.34
2.9
3.6
2.14
1.93
mmol/l
0.21
15
222
10
74
1.36
0.32
1.9
1.7
—
—
—
0
0
31
267
1.17
0.32
1.2
1.2
123.27
142.27
iu/ml
0.08
12
104
14
110
1.28
0.32
1.3
1.2
—
—
—
0
0
21
175
1.21
0.30
1.7
1.9
1.21
1.51
g/l
0.90
16
157
7
57
1.23
0.29
5.7
2.9
2.43
6.64
nmol/l
—
7
57
14
112
1.26
0.28
1.1
1.1
—
1.22
—
0
5
12
94
1.28
0.28
1.2
1.1
—
—
—
0
0
8
62
1.29
0.28
1.8
1.7
—
—
—
0
0
9
77
1.17
0.24
1.3
1.2
—
—
—
0
0
13
106
1.23
0.23
1.2
1.1
—
1.98
—
0
10
5
38
1.32
0.23
2.6
1.5
—
—
—
0
0
5
40
1.25
0.22
1.0
1.0
—
—
—
0
0
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
8
104
0.77
0.21
1.6
1.4
—
—
—
0
0
6
48
1.25
0.20
1.5
1.4
—
—
—
0
0
13
108
1.21
0.20
1.2
1.1
—
2.01
—
0
14
34
373
0.91
0.18
1.8
1.8
—
—
—
0
0
46
426
1.09
0.18
2.9
3.3
—
—
—
0
0
7
61
1.15
0.17
1.9
1.7
—
—
—
0
0
8
68
1.18
0.16
1.8
1.6
—
—
—
0
0
8
70
1.15
0.16
4.1
5.4
314.38
365.22
umol/l
—
8
63
10
118
0.84
0.14
1.2
1.5
—
—
—
0
0
13
115
1.13
0.10
1.3
1.3
—
—
—
0
0
18
196
0.92
0.09
1.1
1.0
—
—
—
0
0
6
58
1.03
0.08
1.0
1.1
—
—
—
0
0
5
61
0.82
0.08
1.2
1.4
—
—
—
0
0
5
61
0.82
0.08
1.2
1.4
—
—
—
0
0
5
61
0.82
0.08
1.2
1.4
—
—
—
0
0
5
64
0.78
0.08
1.2
1.6
—
—
—
0
0
5
65
0.77
0.08
1.6
1.2
—
—
—
0
0
6
72
0.83
0.07
1.2
1.7
—
—
—
0
0
7
80
0.87
0.07
3.6
3.6
57.57
58.78
%
—
7
80
12
109
1.10
0.06
1.7
1.5
—
—
—
0
0
12
110
1.09
0.05
3.6
2.6
1.38
1.62
mg/l
0.56
12
97
12
110
1.09
0.05
1.2
1.3
220.68
260.81
miu/ml
—
6
50
27
260
1.04
0.03
1.6
1.5
—
—
—
0
0
11
102
1.08
0.03
2.0
3.0
9.08
7.92
kpa
1.18
11
102
12
115
1.04
0.00
2.3
2.9
22.20
25.09
mmol/l
2.09
12
115
5
56
0.89
0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
13
130
1.00
-0.00
2.2
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
1.29
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
98
0.92
-0.00
1.3
1.5
—
—
—
0
0
9
89
1.01
-0.00
1.1
1.1
—
1.03
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_EYELIDNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EYELIDNAS | 0.896 [0.7, 1.15] | 0.384 |
| Birth year | 0.992 [0.98, 1.0] | 0.073 |
During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 1323 females with H7_EYELIDNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EYELIDNAS | 0.876 [0.66, 1.16] | 0.352 |
| Birth year | 0.995 [0.99, 1.0] | 0.281 |
During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 1125 males with H7_EYELIDNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_EYELIDNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.082% | 0.185% |
| 5 | 0.511% | 1.379% |
| 10 | 1.246% | 3.172% |
| 15 | 2.316% | 5.973% |
| 20 | 4.031% | 10.469% |
Relationships between endpoints
↥Index endpoint: H7_EYELIDNAS – Other specified and unspecified disorders of eyelid
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data