eyelid disease: A disease involving the eyelid.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
475 |
4. Check minimum number of eventsNone |
475 |
5. Include endpointsNone |
475 |
6. Filter based on genotype QC (FinnGen only) |
475 |
Control definitions (FinnGen only)
- Control exclude
- H7_LIDLACRIMALORBIT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to Other specified and unspecified disorders of eyelid based on the number of shared cases.
Similar with more cases:
- Other disorders of eyelid
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 3094 | 1699 | 1382 |
Only index persons | 2849 | 1573 | 1276 |
Unadjusted period prevalence (%) | |||
Whole population | 0.04 | 0.05 | 0.04 |
Only index persons | 0.05 | 0.06 | 0.05 |
Median age at first event (years) | |||
Whole population | 56.11 | 57.78 | 54.14 |
Only index persons | 56.64 | 58.19 | 54.72 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 475 | 267 | 208 |
Unadjusted period prevalence (%) | 0.09 | 0.09 | 0.09 |
Median age at first event (years) | 62.16 | 60.73 | 63.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 417
- Matched controls
- 4170
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint H7_EYELIDNAS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_EYELIDNAS | 0.896 [0.7, 1.15] | 0.384 |
Birth year | 0.992 [0.98, 1.0] | 0.073 |
During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 1323 females with H7_EYELIDNAS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_EYELIDNAS | 0.876 [0.66, 1.16] | 0.352 |
Birth year | 0.995 [0.99, 1.0] | 0.281 |
During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 1125 males with H7_EYELIDNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_EYELIDNAS.N-year risk | Females | Males |
---|---|---|
1 | 0.082% | 0.185% |
5 | 0.511% | 1.379% |
10 | 1.246% | 3.172% |
15 | 2.316% | 5.973% |
20 | 4.031% | 10.469% |
Relationships between endpoints
↥Index endpoint: H7_EYELIDNAS – Other specified and unspecified disorders of eyelid
GWS hits: -