Other specified and unspecified disorders of eyelid

H7_EYELIDNAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H02.8, H02.9
  • Hospital discharge: ICD-9 374[8-9]
  • Cause of death: ICD-10 H02.8, H02.9
  • Cause of death: ICD-9 374[8-9]

2 out of 7 registries used, show all original rules.

475

4. Check minimum number of events

None

475

5. Include endpoints

None

475

6. Filter based on genotype QC (FinnGen only)

475

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3094 1699 1382
Only index persons 2849 1573 1276
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.04
Only index persons 0.05 0.06 0.05
Median age at first event (years)
Whole population 56.11 57.78 54.14
Only index persons 56.64 58.19 54.72

-FinnGen-

Key figures

All Female Male
Number of individuals 475 267 208
Unadjusted period prevalence (%) 0.09 0.09 0.09
Median age at first event (years) 62.16 60.73 63.98

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
417
Matched controls
4170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02.8
ICD-10 Finland
Other specified disorders of eyelid
8129.9
309.7
259
*
H02.9
ICD-10 Finland
Disorder of eyelid, unspecified
766.9
162.8
150
*
H02.3
ICD-10 Finland
Blepharochalasis
503.2
85.3
82
*
H02.4
ICD-10 Finland
Ptosis of eyelid
118.4
49.0
52
5
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
+∞
38.1
36
*
CBB30
NOMESCO Finland
Excision of lesion of eyelid
13.0
29.1
52
45
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
155.3
28.0
29
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.2
27.1
219
1080
H04.10
ICD-10 Finland
Dry eye syndrome
8.7
26.9
60
79
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
77.5
26.1
29
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
132.6
23.9
25
*
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
+∞
23.1
22
*
CBA10
NOMESCO Finland
Biopsy of eyelid
27.8
23.0
31
12
H00.1
ICD-10 Finland
Chalazion
13.7
19.2
33
26
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
+∞
18.9
18
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
14.7
14
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
44.1
14.2
17
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
14.2
94
374
H01.0
ICD-10 Finland
Blepharitis
7.0
13.9
34
52
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
+∞
12.6
12
*
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
12.6
12
*
CBB00
NOMESCO Finland
Excision of chalazion
48.1
11.9
14
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.2
11.7
157
898
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
+∞
11.5
11
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
11.5
11
*
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
123.2
11.5
12
*
H02.1
ICD-10 Finland
Ectropion of eyelid
112.7
10.5
11
*
CBN20
NOMESCO Finland
Shortening of eyelid retractors
+∞
10.5
10
*
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
5.9
10.3
28
50
CD2S4
NOMESCO Finland
Photography of eye
41.1
10.0
12
*
F29
ICPC
Eye symptom/complaint other
3.5
9.8
46
143
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
9.8
127
710
M79.6
ICD-10 Finland
Pain in limb
2.0
9.7
159
973
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
56.3
9.7
11
*
CFA20
NOMESCO Finland
Biopsy of conjunctiva
102.2
9.5
10
*
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
37.5
9.1
11
*
ZXA10
NOMESCO Finland
Bilateral
2.3
9.0
90
445
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
8.7
59
236
A02BC05
ATC
esomeprazole; systemic
1.9
8.5
171
1116
3748X
ICD-9 Finland
Other disorders of eyelids, Other disorders of eyelid
+∞
8.4
8
*
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
8.4
8
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
8.1
283
2219
WX110
NOMESCO Finland
Local anesthesy
1.8
7.8
281
2213
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.8
7.6
49
191
SPAT1153
SPAT
Removal of sutures
1.9
7.6
142
899
QAJ10
NOMESCO Finland
Browlift
81.4
7.4
8
*
N02BE01
ATC
paracetamol; systemic, rectal
2.1
7.3
356
3071
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
5.6
7.3
20
37
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
7.3
7
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
7.3
7
*
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
7.3
7
*
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
16.1
7.3
11
7
S18
ICPC
Laceration/cut
1.8
7.2
179
1239
ZXA05
NOMESCO Finland
Left side
1.9
7.0
117
706
CBB50
NOMESCO Finland
Excision of lesion of eyelid and reconstruction using graft or flap
22.9
6.7
9
*
H02AB06
ATC
prednisolone; systemic
1.7
6.6
193
1395
N02AX02
ATC
tramadol; systemic, rectal
1.7
6.4
176
1241
H00.00
ICD-10 Finland
Hordeolum
4.3
6.4
22
53
R51.80
ICD-10 Finland
Headache
2.3
6.4
61
294
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.7
6.3
41
161
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
6.3
94
542
WX002
NOMESCO Finland
Sedation and analgesia
2.0
6.3
87
486
H062, E050
ICD-10 Finland
NA
+∞
6.3
6
*
CBB12
NOMESCO Finland
Resection of lax skin in lower eyelid
+∞
6.3
6
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
6.3
6
*
XCK00
NOMESCO Finland
Perimetry
3.0
6.2
35
123
M03BX02
ATC
tizanidine; oral
1.7
6.1
247
1934

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
35
90
4.12
12.50
3.3
1.5
5.3
7.6
iu/l
0.35
14
24
271
1971
1.87
10.05
6.1
7.1
1.2
1.2
mmol/l
0.16
240
1675
447
3914
3.41
10.05
16.4
14.4
20.7
23.8
mg/l
1.44
374
3094
182
1177
1.89
9.69
3.9
3.9
7.4
7.4
ph
0.48
23
214
299
2274
1.85
9.30
10.2
9.5
4.1
4.1
e9/l
0.11
264
2008
358
2891
1.97
9.16
4.0
4.1
11.7
12.4
mm/h
0.46
334
2660
143
870
1.92
9.07
5.3
3.6
—
—
—
0
0
263
1940
1.80
8.88
6.8
5.5
0.6
0.6
e9/l
0.79
223
1683
125
734
1.95
8.77
3.7
3.9
32.8
403.9
ng/l
4.86
98
593
263
1945
1.79
8.75
6.9
5.5
0.0
0.0
e9/l
1.14
224
1693
226
1599
1.79
8.75
2.0
2.0
97.7
94.3
pmol/l
0.53
111
813
249
1813
1.78
8.73
5.7
6.2
1.2
1.2
mmol/l
0.17
234
1635
267
2009
1.75
8.14
7.0
5.9
0.2
0.2
e9/l
0.99
231
1774
16
32
5.14
7.71
1.9
1.3
0.2
0.4
g/l
—
10
24
16
32
5.14
7.71
1.9
1.3
2.0
2.9
g/l
—
10
24
16
32
5.14
7.71
1.9
1.3
5.5
7.1
g/l
—
10
24
263
1990
1.72
7.68
7.1
5.5
1.9
2.0
e9/l
0.28
228
1765
232
1697
1.72
7.66
5.2
5.0
36.0
35.4
g/l
0.92
218
1588
255
1919
1.71
7.55
4.7
3.6
0.0
0.0
estimate
0.50
30
349
252
1900
1.70
7.33
5.9
4.8
0.0
0.0
estimate
0.00
34
357
16
34
4.84
7.21
2.0
1.2
—
—
—
0
0
148
971
1.76
7.10
6.9
6.9
—
—
—
0
0
353
2946
1.77
6.81
4.6
3.8
14.8
14.9
pmol/l
0.03
326
2642
410
3588
2.04
6.76
5.5
4.6
1.9
2.3
mu/l
0.61
379
3232
20
54
3.82
6.70
2.1
1.9
0.6
0.9
g/l
0.56
13
46
151
1016
1.71
6.54
2.8
2.7
10386.2
7503.4
umol/l
0.23
133
879
247
1895
1.63
6.39
4.7
3.6
0.0
0.0
estimate
0.00
33
361
334
2800
1.65
5.74
5.1
3.9
—
—
—
0
0
84
494
1.85
5.69
1.6
1.3
—
—
—
0
0
427
3846
2.09
5.68
5.6
4.7
5.9
6.0
mmol/l
0.73
397
3482
454
4196
2.85
5.65
12.5
10.6
25.7
26.3
u/l
0.35
449
4035
322
2681
1.62
5.63
4.5
4.2
—
—
—
0
0
358
3072
1.67
5.44
8.3
7.6
76.0
79.6
u/l
1.20
344
2865
287
2337
1.58
5.41
4.8
5.0
6.5
6.8
mmol/l
2.07
269
2190
236
1839
1.56
5.39
6.4
5.5
56.1
57.5
%
1.10
221
1731
445
4092
2.39
5.29
16.2
13.5
—
—
—
0
0
463
4344
3.61
5.22
26.5
21.3
248.5
247.3
e9/l
0.16
457
4228
463
4346
3.59
5.17
26.5
21.3
6.8
6.7
e9/l
0.06
453
4220
463
4346
3.59
5.17
26.6
21.3
4.5
4.5
e12/l
0.07
452
4220
232
1814
1.55
5.14
6.7
5.6
3.2
2.9
%
0.81
218
1694
127
863
1.64
5.13
1.7
1.6
1.1
1.2
mg/l
0.30
106
673
38
173
2.30
5.12
4.8
4.3
—
—
—
0
0
233
1826
1.54
5.09
6.8
5.9
8.8
8.7
%
0.18
218
1716
263
2119
1.54
5.05
6.0
6.5
10.7
11.3
umol/l
0.57
251
2016
225
1758
1.53
4.94
6.7
5.7
0.7
0.7
%
0.60
209
1640
236
1864
1.53
4.92
6.7
5.8
28.6
27.5
%
0.87
218
1741
74
441
1.80
4.78
1.7
1.6
—
—
—
0
0
110
733
1.65
4.77
2.8
3.4
2.4
2.5
mmol/l
0.25
98
646
442
4080
2.20
4.74
20.4
17.1
4.0
4.0
mmol/l
0.05
436
3963
153
1106
1.57
4.73
3.1
3.1
0.2
0.4
e6/l
3.53
112
828
441
4068
2.17
4.73
20.2
17.0
139.6
139.7
mmol/l
0.82
435
3953
211
1638
1.52
4.71
3.0
2.6
99.4
144.3
ug/l
3.66
198
1499
68
397
1.83
4.70
2.7
3.5
—
—
—
0
0
426
3890
1.92
4.59
5.3
4.6
4.7
4.7
mmol/l
0.13
400
3574
432
3968
1.98
4.49
6.1
5.1
2.8
2.7
mmol/l
0.17
403
3617
145
1049
1.55
4.42
3.0
3.0
—
—
—
0
0
423
3865
1.86
4.38
5.0
4.5
1.4
1.5
mmol/l
0.89
396
3528
413
3749
1.78
4.35
4.5
4.1
1.4
1.3
mmol/l
1.41
381
3405
65
385
1.80
4.28
2.8
3.4
2.1
1.9
mmol/l
0.21
52
304
166
1252
1.50
4.12
3.7
4.1
12.6
7.5
mg/mmol
0.69
104
789
76
477
1.71
4.10
5.3
9.2
1.2
1.2
mmol/l
0.06
58
371
391
3514
1.64
4.07
17.7
15.7
39.0
39.9
%
1.02
271
2449
165
1249
1.49
4.01
3.0
3.2
7.0
7.4
mmol/l
0.63
143
1041
158
1187
1.50
3.98
3.0
3.3
76.8
162.5
mg/l
0.52
96
755
405
3682
1.68
3.91
6.6
5.9
40.1
40.2
mmol/mol
0.08
381
3398
59
350
1.78
3.87
3.1
2.5
4.5
7.8
ug/l
1.27
53
314
52
298
1.84
3.82
2.5
2.4
10.4
10.6
g/l
0.13
46
274
215
1731
1.44
3.74
8.3
9.2
0.0
0.0
e9/l
0.43
166
1423
173
1339
1.46
3.70
3.2
3.9
2.3
2.4
mmol/l
0.23
157
1158
204
1634
1.44
3.61
10.5
9.3
1.2
1.3
inr
0.40
51
449
161
1237
1.46
3.55
2.4
2.0
234.9
269.7
u/l
0.16
148
1155
129
950
1.49
3.52
1.5
1.5
23.6
20.8
nmol/l
0.34
117
791
166
1285
1.45
3.51
6.0
5.4
—
—
—
0
0
56
342
1.72
3.34
5.2
8.9
—
—
—
0
0
116
848
1.49
3.26
6.4
4.1
1.0
1.0
kg/l
—
6
102
47
275
1.79
3.25
5.0
6.4
—
—
—
0
0
223
1840
1.40
3.24
4.1
4.0
—
—
—
0
0
156
1209
1.43
3.24
3.6
3.1
—
—
—
0
0
175
1385
1.42
3.23
4.3
3.7
76.3
70.3
e6/l
0.05
123
1001
55
340
1.70
3.15
6.4
3.3
—
—
—
0
0
26
126
2.13
3.08
11.9
10.4
—
—
—
0
0
42
242
1.81
3.06
1.2
1.2
—
—
—
0
0
126
954
1.44
2.93
2.4
2.1
2.6
3.2
mg/l
2.10
111
817
117
878
1.44
2.85
5.4
4.8
—
—
—
0
0
27
140
1.98
2.71
1.1
1.0
—
—
—
0
0
135
1049
1.40
2.70
1.7
1.6
1.4
1.4
mmol/l
0.27
116
867
158
1263
1.38
2.66
2.9
2.5
52.9
56.0
u/l
0.89
148
1175
151
1201
1.38
2.61
2.7
3.2
762.0
1346.1
ng/l
4.21
128
1026
80
567
1.49
2.60
2.1
2.3
2.3
2.3
g/l
0.05
74
520
11
39
2.86
2.49
2.0
2.1
—
—
—
0
0
187
1550
1.34
2.46
4.0
3.7
279.5
39.7
ng/l
0.52
126
1108
6
12
5.05
2.41
1.0
1.2
—
—
—
0
0
71
500
1.49
2.38
1.3
1.3
220.0
421.5
titre
2.52
14
110
75
536
1.47
2.34
2.1
2.4
20.3
22.2
%
0.77
60
457
9
28
3.26
2.32
1.1
1.1
—
2.2
—
0
6
8
23
3.52
2.28
1.4
1.3
—
—
—
0
0
83
609
1.44
2.27
1.7
1.8
28.9
29.7
s
0.96
78
592
80
584
1.44
2.24
1.5
2.0
—
—
—
0
0
68
481
1.48
2.24
1.6
1.4
—
—
—
0
0
148
1205
1.33
2.15
3.4
3.2
20.5
65.0
e6/l
1.95
108
933
77
564
1.44
2.12
1.8
1.7
—
—
—
0
0
135
1086
1.34
2.12
3.6
4.3
—
—
—
0
0
185
1561
1.30
2.07
2.8
2.1
—
—
—
0
0
18
91
2.02
1.98
1.4
1.2
—
—
—
0
0
12
51
2.39
1.96
1.3
1.2
—
—
—
0
0
32
196
1.68
1.95
2.9
3.6
—
—
—
0
0
42
276
1.57
1.95
1.2
1.1
—
—
—
0
0
95
733
1.37
1.95
1.5
1.7
1107.0
1211.0
nmol/l
0.51
81
552
83
627
1.39
1.93
2.1
2.3
13.1
12.9
umol/l
0.07
78
579
58
410
1.47
1.93
1.6
1.5
—
—
—
0
0
40
261
1.58
1.91
1.3
1.4
—
—
—
0
0
7
22
3.21
1.88
1.3
1.1
—
—
—
0
0
21
116
1.85
1.81
2.0
1.6
37.4
41.7
nmol/l
0.40
21
111
14
67
2.12
1.77
1.9
2.9
—
—
—
0
0
10
41
2.47
1.76
1.3
1.3
—
—
—
0
0
104
828
1.33
1.74
2.5
2.5
3.9
5.9
e6/l
0.82
90
737
19
104
1.86
1.69
4.6
2.8
—
—
—
0
0
26
157
1.69
1.69
1.4
1.3
—
—
—
0
0
6
19
3.18
1.66
1.2
1.2
—
—
—
0
0
8
31
2.61
1.66
6.9
2.8
—
—
—
0
0
52
378
1.42
1.53
1.6
1.4
—
—
—
0
0
6
21
2.88
1.51
1.0
1.0
—
—
—
0
0
12
58
2.10
1.50
1.2
1.2
1.0
8.8
u/ml
—
5
25
9
38
2.39
1.46
1.2
1.3
—
—
nmol/l
—
0
0
9
40
2.27
1.40
1.3
1.1
—
—
—
0
0
25
158
1.61
1.40
1.7
1.7
—
—
—
0
0
20
119
1.71
1.40
1.1
1.2
—
—
—
0
0
59
446
1.37
1.39
2.9
2.5
4.5
8.8
umol/l
4.64
52
389
11
53
2.10
1.39
1.5
2.5
—
—
—
0
0
69
535
1.34
1.39
24.7
22.0
1.3
1.3
inr
—
5
66
15
82
1.86
1.37
2.3
4.3
—
—
—
0
0
6
23
2.63
1.37
8.2
2.7
—
—
—
0
0
28
414
0.66
1.36
4.5
3.9
—
—
—
0
0
78
618
1.31
1.36
1.2
1.3
1.3
11.2
u/ml
3.26
24
245
19
113
1.71
1.34
3.9
4.5
—
—
—
0
0
38
269
1.45
1.30
1.9
2.7
—
—
—
0
0
41
295
1.43
1.29
2.2
2.2
12.0
13.2
nmol/l
0.51
35
268
8
35
2.31
1.27
2.0
2.8
—
—
—
0
0
41
297
1.42
1.25
1.7
1.4
—
—
—
0
0
47
349
1.38
1.25
1.4
1.4
—
—
—
0
0
43
316
1.40
1.22
3.2
3.4
83.3
82.2
ng/l
0.02
36
281
151
1317
1.21
1.17
5.2
5.0
1.7
2.9
ug/l
2.34
138
1168
90
743
1.26
1.15
1.5
1.4
2.3
2.6
g/l
0.43
53
441
15
88
1.73
1.12
2.8
1.7
216.5
218.1
pmol/l
0.02
15
81
17
104
1.66
1.11
1.2
1.0
—
—
—
0
0
99
831
1.24
1.10
1.3
1.2
1.3
2.2
u/ml
0.64
20
228
8
41
1.97
1.09
1.4
1.3
—
—
—
0
0
7
32
2.20
1.08
1.9
1.2
—
—
—
0
0
92
769
1.24
1.06
3.3
2.7
561.9
560.3
mosm/kgh2o
0.02
77
665
12
68
1.78
1.01
1.6
1.3
—
—
—
0
0
7
35
2.01
1.00
1.1
1.3
—
—
—
0
0
52
409
1.30
0.98
1.8
1.6
—
—
—
0
0
79
657
1.24
0.96
1.2
1.3
15.7
39.0
iu/ml
3.66
25
197
66
538
1.26
0.95
1.2
1.2
—
—
—
0
0
6
28
2.16
0.92
14.2
14.8
1101.8
1657.9
nmol/l
—
6
28
16
102
1.59
0.91
1.3
1.2
—
72.9
—
0
7
13
79
1.66
0.89
1.4
2.1
—
—
—
0
0
8
45
1.79
0.84
1.1
1.5
0.2
0.2
nmol/l
—
8
34
98
847
1.20
0.83
1.4
1.7
447.3
18732415.7
pmol/l
0.79
85
694
6
32
1.89
0.82
1.7
1.1
—
—
—
0
0
40
314
1.30
0.79
5.1
4.2
0.1
0.4
%
—
7
77
6
33
1.83
0.79
1.2
1.2
—
—
—
0
0
117
1033
1.18
0.78
1.3
1.4
—
—
—
0
0
39
306
1.30
0.78
6.2
4.4
0.0
0.2
%
—
7
84
6
34
1.77
0.76
2.3
2.4
—
—
—
0
0
43
343
1.28
0.76
2.7
2.5
71.6
69.8
e9/l
0.12
34
273
11
67
1.66
0.75
1.5
1.2
—
—
—
0
0
119
1058
1.17
0.73
6.7
3.9
0.0
0.0
estimate
0.00
30
351
7
39
1.81
0.72
2.3
1.8
—
—
—
0
0
58
484
1.23
0.71
1.5
1.6
—
—
—
0
0
9
58
1.56
0.70
1.1
2.6
107.3
105.7
mmol/l
—
9
58
9
58
1.56
0.70
1.1
2.6
4.0
4.1
mmol/l
—
9
58
9
58
1.56
0.70
1.1
2.6
—
—
—
0
0
5
27
1.86
0.68
1.8
1.9
—
—
—
0
0
139
1259
1.15
0.67
2.4
2.3
—
—
—
0
0
40
323
1.26
0.66
6.1
4.4
0.0
0.1
%
—
7
96
7
44
1.60
0.65
1.3
1.7
—
—
—
0
0
7
44
1.60
0.65
1.3
1.7
—
—
—
0
0
7
44
1.60
0.65
1.3
1.7
—
—
—
0
0
7
44
1.60
0.65
1.3
1.7
—
—
—
0
0
53
443
1.22
0.65
2.6
2.2
155.6
134.2
ug/g
0.24
43
351
27
210
1.30
0.60
1.3
1.3
—
—
—
0
0
14
196
0.71
0.58
3.7
3.5
—
—
—
0
0
6
38
1.59
0.54
1.3
1.2
—
—
—
0
0
17
125
1.37
0.54
1.0
1.1
—
—
—
0
0
26
325
0.79
0.53
4.3
3.6
—
—
—
0
0
29
235
1.25
0.49
1.2
1.2
141.0
139.2
iu/ml
—
10
92
26
208
1.26
0.49
9.2
13.7
—
—
—
0
0
11
76
1.46
0.48
2.9
4.3
30.6
26.6
mg/l
—
5
51
5
81
0.61
0.46
1.2
1.1
—
—
—
0
0
7
49
1.43
0.46
1.0
1.2
—
—
—
0
0
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
11
77
1.44
0.46
1.5
1.6
—
—
—
0
0
10
69
1.46
0.44
1.9
1.5
—
—
—
0
0
26
316
0.81
0.43
1.3
1.4
—
—
—
0
0
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
10
70
1.44
0.42
2.0
3.1
—
—
—
0
0
41
352
1.18
0.42
6.0
4.2
0.6
1.1
%
—
8
112
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.8
—
4687.4
—
0
8
0
17
0.00
0.40
0.0
9.9
—
0.7
—
0
17
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
30
251
1.21
0.40
2.1
1.6
—
—
—
0
0
13
97
1.35
0.40
1.4
1.2
—
—
—
0
0
18
142
1.28
0.39
1.5
3.6
1.1
0.2
g/l
—
10
53
9
68
1.33
0.38
1.2
1.1
—
—
—
0
0
23
191
1.21
0.34
2.4
2.4
—
—
—
0
0
6
45
1.34
0.34
1.2
1.2
—
—
—
0
0
6
46
1.31
0.33
1.7
1.2
—
—
—
0
0
16
128
1.26
0.32
1.7
1.6
—
—
—
0
0
28
239
1.18
0.32
2.4
2.5
—
—
—
0
0
14
110
1.28
0.32
1.4
1.5
—
—
—
0
0
19
156
1.23
0.31
1.2
1.1
—
—
—
0
0
7
52
1.35
0.31
1.3
1.2
—
—
—
0
0
22
261
0.84
0.31
3.1
3.7
7.4
7.4
ph
—
5
28
14
112
1.26
0.28
1.4
1.5
—
—
—
0
0
14
112
1.26
0.28
1.4
1.5
—
—
—
0
0
14
112
1.26
0.28
1.4
1.4
285.6
281.8
ug/g
—
8
62
14
112
1.26
0.28
1.4
1.5
—
—
—
0
0
33
290
1.15
0.28
1.4
1.4
—
—
—
0
0
8
65
1.23
0.27
1.1
1.0
—
—
—
0
0
131
1377
0.93
0.26
3.0
3.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
48
441
1.10
0.21
1.5
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.5
—
—
—
0
0
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
7
58
1.21
0.18
2.0
2.9
—
—
—
0
0
7
58
1.21
0.18
4.6
5.6
302.6
376.8
umol/l
—
7
51
7
61
1.15
0.17
1.7
1.7
—
—
—
0
0
80
760
1.06
0.17
2.6
2.9
0.6
0.8
ug/l
2.28
58
487
9
78
1.16
0.15
2.6
1.9
70.2
59.4
%
—
9
78
7
88
0.79
0.14
4.0
4.4
—
—
—
0
0
11
94
1.17
0.13
2.5
2.8
—
—
—
0
0
12
106
1.14
0.10
1.5
1.5
—
—
—
0
0
12
106
1.14
0.10
3.6
2.5
1.4
1.6
mg/l
0.47
12
93
6
54
1.11
0.09
4.7
2.9
3.3
81.4
u/ml
—
6
49
7
64
1.10
0.08
1.7
1.4
—
—
—
0
0
8
77
1.04
0.07
2.5
1.7
—
—
—
0
0
47
452
1.04
0.07
3.8
4.5
3.7
34.8
ug/l
1.12
40
380
7
83
0.84
0.07
1.4
1.7
—
—
—
0
0
9
86
1.05
0.07
1.0
1.7
—
—
—
0
0
10
91
1.10
0.04
1.5
1.6
—
—
—
0
0
10
94
1.07
0.01
2.0
3.1
9.2
7.9
kpa
—
10
86
16
154
1.04
0.00
1.5
1.8
—
—
—
0
0
10
104
0.96
0.00
2.5
3.1
22.6
25.1
mmol/l
—
10
92
10
98
1.02
0.00
1.3
1.3
—
—
—
0
0
23
227
1.01
0.00
1.7
1.4
—
—
—
0
0
10
101
0.99
0.00
1.3
1.3
217.7
277.6
miu/ml
—
5
49
16
159
1.01
0.00
3.2
2.8
—
—
—
0
0
120
1202
1.00
0.00
3.5
3.9
—
—
—
0
0
105
1049
1.00
0.00
3.4
3.3
—
—
—
0
0
0
9
0.00
0.00
0.0
2.3
—
19.0
—
0
9
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
7
74
0.95
0.00
3.6
3.3
57.6
58.6
%
—
7
74
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
8
79
1.01
0.00
1.5
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
7.9
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
5
56
0.89
0.00
1.2
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
19.3
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
9.2
3.7
1.2
1.1
%
—
5
51
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
7
73
0.96
0.00
3.6
3.1
4.3
4.4
e9/l
—
7
73
5
56
0.89
0.00
7.4
2.9
2.8
6.8
nmol/l
—
5
56
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_EYELIDNAS and mortality.

Females

Parameter HR [95% CI] p-value
H7_EYELIDNAS 0.896 [0.7, 1.15] 0.384
Birth year 0.992 [0.98, 1.0] 0.073

During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 1323 females with H7_EYELIDNAS died.

Males

Parameter HR [95% CI] p-value
H7_EYELIDNAS 0.876 [0.66, 1.16] 0.352
Birth year 0.995 [0.99, 1.0] 0.281

During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 1125 males with H7_EYELIDNAS died.

Mortality risk

Mortality risk for people of age

years, who have H7_EYELIDNAS.

N-year risk Females Males
1 0.082% 0.185%
5 0.511% 1.379%
10 1.246% 3.172%
15 2.316% 5.973%
20 4.031% 10.469%

Relationships between endpoints

Index endpoint: H7_EYELIDNAS – Other specified and unspecified disorders of eyelid

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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