obsolete_alopecia:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
336 |
4. Check minimum number of eventsNone |
336 |
5. Include endpoints |
336 |
6. Filter based on genotype QC (FinnGen only) |
336 |
Control definitions (FinnGen only)
- Control exclude
- L12_DISORDSKINAPPENDIX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L60-L75
- Name in latin
- Alia alopecia non cicatrisans
Similar endpoints
↥List of similar endpoints to Other nonscarring hair loss based on the number of shared cases.
Similar with more cases:
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2372 | 2134 | 224 |
Only index persons | 2265 | 2061 | 204 |
Unadjusted period prevalence (%) | |||
Whole population | 0.06 | 0.06 | 0.01 |
Only index persons | 0.07 | 0.08 | 0.01 |
Median age at first event (years) | |||
Whole population | 38.44 | 40.23 | 21.33 |
Only index persons | 39.24 | 40.85 | 22.94 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 336 | 324 | 12 |
Unadjusted period prevalence (%) | 0.11 | 0.11 | 0.01 |
Median age at first event (years) | 46.12 | 46.46 | 36.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 292
- Matched controls
- 2918
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint L12_HAIRLOSSNONSCAR and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
L12_HAIRLOSSNONSCAR | 1.293 [1.01, 1.66] | 0.046 |
Birth year | 0.992 [0.98, 1.0] | 0.074 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 1581 females with L12_HAIRLOSSNONSCAR died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_HAIRLOSSNONSCAR.N-year risk | Females | Males |
---|---|---|
1 | 0.144% | No data |
5 | 0.728% | No data |
10 | 1.747% | No data |
15 | 3.274% | No data |
20 | 5.749% | No data |
Relationships between endpoints
↥Index endpoint: L12_HAIRLOSSNONSCAR – Other nonscarring hair loss
GWS hits: 1