Telogen effluvium

L12_TELOGEFFLU

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L65.0#
  • Cause of death: ICD-10 L65.0#

2 out of 7 registries used, show all original rules.

70

4. Check minimum number of events

None

70

5. Include endpoints

None

70

6. Filter based on genotype QC (FinnGen only)

69

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L65
Name in latin
Effluvium telogenicum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 541 499 35
Only index persons 520 488 32
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.02 0.02 0.00
Median age at first event (years)
Whole population 37.78 39.08 18.84
Only index persons 38.14 39.45 18.28

-FinnGen-

Key figures

All Female Male
Number of individuals 69 64 5
Unadjusted period prevalence (%) 0.02 0.02 0.00
Median age at first event (years) 49.55 49.83 45.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
70
Matched controls
700
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L65.0
ICD-10 Finland
Telogen effluvium
+∞
100.6
70
*
D07AC01
ATC
betamethasone; topical
4.8
9.6
42
167
C03DA01
ATC
spironolactone; oral
6.1
9.2
19
40
L65.9
ICD-10 Finland
Nonscarring hair loss, unspecified
89.1
7.6
8
*
L73.8
ICD-10 Finland
Other specified follicular disorders
+∞
7.4
7
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
9
8
12.67
5.46
1.1
1.0
18.42
21.86
umol/l
—
9
8
70
588
+∞
4.72
21.6
12.7
22.43
18.10
mg/l
0.43
55
443
8
10
8.85
4.18
1.0
1.3
—
—
—
0
0
21
94
2.76
3.39
1.5
1.5
192.00
513.60
titre
—
5
25
13
46
3.24
3.11
6.2
5.0
—
—
—
0
0
43
280
2.39
3.07
8.8
5.1
—
—
—
0
0
19
85
2.70
3.04
1.1
1.2
—
—
—
0
0
5
5
10.62
3.02
1.4
1.2
—
—
—
0
0
14
55
2.93
2.82
1.4
1.5
—
—
—
0
0
43
288
2.28
2.78
5.0
2.5
107.49
78.15
ug/l
0.53
43
266
36
226
2.22
2.70
2.4
1.8
99.12
101.57
pmol/l
0.11
23
94
42
289
2.13
2.41
9.1
5.2
0.55
0.54
e9/l
0.17
35
262
24
133
2.22
2.39
1.3
1.3
13.23
25.14
iu/ml
—
9
46
42
290
2.12
2.38
9.1
5.2
0.05
0.04
e9/l
1.08
35
261
54
414
2.33
2.31
6.7
4.2
—
—
—
0
0
43
303
2.09
2.27
9.1
5.1
1.98
1.88
e9/l
0.39
37
282
43
303
2.09
2.27
9.7
5.8
0.20
0.16
e9/l
1.11
37
278
37
247
2.06
2.26
3.1
1.9
—
—
—
0
0
23
128
2.19
2.25
6.5
1.7
1.30
0.74
mg/l
0.54
14
99
7
19
3.97
2.21
1.1
1.1
—
—
—
0
0
26
157
2.04
2.04
1.4
1.2
0.94
1.37
u/ml
—
7
43
7
21
3.58
2.02
1.0
1.4
—
—
—
0
0
15
74
2.31
1.92
2.2
2.7
—
—
—
0
0
13
61
2.39
1.85
1.5
3.3
14.00
5.40
umol/l
0.49
13
53
15
76
2.24
1.81
1.4
1.1
—
—
—
0
0
36
255
1.85
1.71
13.9
7.6
0.00
0.00
e9/l
-0.00
28
210
7
27
2.76
1.56
2.3
2.0
—
—
—
0
0
45
349
1.81
1.53
10.7
9.1
4.06
4.09
e9/l
0.04
39
311
50
401
1.86
1.52
4.4
3.2
—
—
—
0
0
5
16
3.28
1.46
4.6
3.0
—
—
—
0
0
9
42
2.31
1.40
1.9
1.5
—
—
—
0
0
70
662
+∞
1.39
30.2
18.2
6.90
6.45
e9/l
1.16
70
646
70
662
+∞
1.39
30.0
18.1
30.48
30.11
pg
1.06
70
652
70
662
+∞
1.39
30.1
18.2
4.35
4.44
e12/l
1.11
70
647
70
662
+∞
1.39
30.1
18.3
132.23
133.27
g/l
0.31
70
653
70
661
+∞
1.39
30.0
18.2
91.65
90.66
fl
1.01
70
651
70
661
+∞
1.39
30.3
18.3
273.69
261.60
e9/l
0.79
70
648
21
133
1.83
1.38
1.2
1.3
30.91
4.34
u/ml
0.41
11
48
25
168
1.76
1.35
1.5
1.6
—
—
—
0
0
38
288
1.70
1.34
3.3
3.5
0.00
0.00
estimate
—
8
57
5
18
2.91
1.31
1.4
1.3
—
—
—
0
0
5
18
2.91
1.31
1.8
1.1
—
—
—
0
0
5
18
2.91
1.31
3.2
1.4
—
—
—
0
0
8
36
2.38
1.29
8.3
2.7
—
—
—
0
0
21
136
1.78
1.28
1.6
1.3
2.92
2.14
g/l
0.88
14
76
31
225
1.68
1.26
14.1
10.8
1.36
1.16
inr
—
9
76
5
19
2.75
1.23
1.2
1.9
0.25
0.23
g/l
—
5
19
6
26
2.43
1.21
2.8
1.3
—
—
—
0
0
15
89
1.87
1.19
9.1
3.7
0.81
0.82
mmol/l
0.14
15
81
17
106
1.80
1.16
1.9
1.7
—
—
—
0
0
13
74
1.93
1.16
1.8
1.6
—
—
—
0
0
19
123
1.75
1.15
5.8
4.0
—
—
—
0
0
19
123
1.75
1.15
3.9
3.4
—
—
—
0
0
11
59
2.03
1.15
1.2
1.1
—
—
—
0
0
7
32
2.32
1.12
2.4
7.4
2.00
1.19
mmol/l
—
7
32
9
46
2.10
1.09
5.3
3.9
4.41
4.64
pmol/l
—
9
38
10
53
2.03
1.07
1.5
1.5
—
—
—
0
0
26
187
1.62
1.07
8.3
3.1
—
—
—
0
0
24
170
1.63
1.04
2.6
2.1
—
—
—
0
0
11
62
1.92
1.01
1.5
1.2
—
—
—
0
0
6
29
2.17
0.92
3.0
3.5
—
—
—
0
0
8
45
1.88
0.88
1.1
2.1
—
—
—
0
0
36
290
1.50
0.86
4.7
5.0
0.00
0.00
estimate
—
8
54
6
32
1.95
0.84
4.2
8.0
—
—
—
0
0
26
197
1.51
0.83
2.8
3.4
13.68
19.76
ng/l
1.18
13
123
27
207
1.50
0.81
5.3
3.6
13.69
67.05
e6/l
1.65
20
144
22
162
1.52
0.79
10.0
7.4
—
—
—
0
0
36
295
1.45
0.77
3.4
3.5
0.00
0.00
estimate
—
8
54
5
24
2.16
0.76
1.2
1.1
—
—
—
0
0
7
40
1.83
0.74
1.1
1.3
—
—
—
0
0
7
43
1.70
0.69
3.3
2.3
0.90
2.24
mmol/l
—
7
35
8
52
1.61
0.62
1.9
1.2
—
—
—
0
0
12
81
1.58
0.62
1.9
1.6
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
20
152
1.44
0.61
4.0
2.7
—
—
—
0
0
22
173
1.40
0.56
4.6
2.8
53.30
17.29
e6/l
0.57
17
129
20
155
1.41
0.55
3.6
3.3
—
—
—
0
0
6
39
1.59
0.54
2.8
2.8
79.90
70.93
e9/l
—
6
32
10
68
1.55
0.50
2.0
1.7
—
—
—
0
0
0
15
0.00
0.42
0.0
2.4
—
3.90
—
0
15
0
17
0.00
0.41
0.0
3.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.4
—
1.51
—
0
18
5
36
1.42
0.39
2.4
1.1
—
—
—
0
0
5
78
0.61
0.38
1.8
1.4
—
—
—
0
0
6
42
1.47
0.36
3.0
2.3
—
—
—
0
0
54
512
1.24
0.25
25.9
15.4
14.70
14.85
%
0.08
54
503
15
127
1.23
0.22
3.7
2.9
49.06
49.71
mg/l
—
8
74
0
11
0.00
0.21
0.0
1.3
—
26.48
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
20
176
1.19
0.20
2.0
3.2
—
—
—
0
0
21
231
0.87
0.15
3.3
2.6
—
—
—
0
0
5
48
1.04
0.09
2.4
3.4
—
—
—
0
0
15
139
1.10
0.06
3.9
3.3
15.51
8.62
mg/mmol
—
8
80
14
138
1.02
0.00
2.6
1.9
—
—
—
0
0
15
151
0.99
0.00
2.9
3.6
0.00
0.00
estimate
—
7
55
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
0.89
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
66
0.90
-0.00
2.3
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
55
0.90
-0.00
4.2
6.4
102.00
103.96
mmol/l
—
5
55
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
3.89
—
0
8
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
119.40
—
0
5
0
8
0.00
-0.00
0.0
2.3
—
107.88
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
31.00
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
97.48
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
60.86
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
241.11
—
0
9
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_TELOGEFFLU and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_TELOGEFFLU.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: L12_TELOGEFFLU – Telogen effluvium

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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