sclerosing cholangitis: A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.
Cholangitis (primary sclerosing, PSC), with reimbursement 202
DOID EFO Endpoint Browser PheWeb
K11_CHOLANGI_STRICT
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditions
|
31113 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
702 |
4. Check minimum number of eventsNone |
702 |
5. Include endpointsNone |
702 |
6. Filter based on genotype QC (FinnGen only) |
685 |
Control definitions (FinnGen only)
- Control exclude
- K11_IBD_STRICT_PSC
- Control conditions
- not K11_REIMB_202
Extra metadata
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- K83
- Name in latin
- Cholangitis
Similar endpoints
↥List of similar endpoints to
Cholangitis (primary sclerosing, PSC), with reimbursement 202
based on the number of shared cases.
Similar with more cases:
- Cholangitis (primary sclerosing, PSC)
- Reimbursement for rheumatic diseases
- Disorders of gallbladder, biliary tract and pancreas
- Gastrointestinal diseases
- Any reimbursement code in KELA
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2699 | 1491 | 1192 |
| Only index persons | 2473 | 1364 | 1109 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.05 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 52.12 | 57.80 | 44.91 |
| Only index persons | 50.38 | 56.59 | 42.74 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 685 | 376 | 309 |
| Unadjusted period prevalence (%) | 0.14 | 0.13 | 0.14 |
| Median age at first event (years) | 45.60 | 49.23 | 41.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 702
- Matched controls
- 7020
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
56.7
318.5
185
44
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
95.3
307.7
252
41
A05AA02
ATC
ursodeoxycholic acid; oral
946.9
307.7
567
31
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
58.2
307.7
232
59
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
156.0
307.7
238
23
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
47.5
307.7
266
89
K83.0
ICD-10 Finland
Cholangitis
4503599627370496.0
307.7
697
22
L04AX01
ATC
azathioprine; systemic
40.4
307.7
245
92
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
48.5
307.7
376
163
UJF30
NOMESCO Finland
Ileoscopy through colon
22.8
307.7
377
340
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
374.9
307.7
402
25
K51.5
ICD-10 Finland
Left sided colitis
53.8
307.7
298
95
A07EC02
ATC
mesalazine; oral, rectal
40.3
307.7
370
189
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
20.6
307.7
337
301
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
+∞
307.7
702
*
UJK02
NOMESCO Finland
ERCP
70.9
307.7
249
54
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
51.9
302.1
179
46
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
95.1
285.6
150
20
A07EA06
ATC
budesonide; oral, local oral
21.7
232.5
189
117
A07EC01
ATC
sulfasalazine; oral, rectal
26.2
225.3
166
82
K83.1
ICD-10 Finland
Obstruction of bile duct
56.2
224.5
129
28
UJF32
NOMESCO Finland
Coloscopy
10.5
223.6
443
980
K51.8
ICD-10 Finland
Other ulcerative colitis
37.8
219.1
140
46
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
57.1
208.2
119
25
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
59.0
200.9
114
23
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
58.0
182.9
104
21
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
8.4
179.2
438
1157
WX404
NOMESCO Finland
Intravenous generell anesthesy
7.1
151.0
366
930
WX402
NOMESCO Finland
General anaesthesia
7.0
147.8
363
931
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.9
146.7
267
507
K50.8
ICD-10 Finland
Other Crohn disease
26.6
142.3
101
44
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
50.7
138.9
81
18
K76.9
ICD-10 Finland
Liver disease, unspecified
34.3
138.9
90
30
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
64.5
135.1
75
13
L04AX03
ATC
methotrexate; systemic
16.0
134.7
123
92
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
52.4
129.6
75
16
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
61.6
128.6
72
13
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.1
127.0
389
1190
127
Kela drug reimbursment
Transplant complication
25.3
123.6
89
40
L04AA06
ATC
mycophenolic acid; systemic
26.7
120.6
85
36
K50.1
ICD-10 Finland
Crohn disease of large intestine
27.1
119.9
84
35
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
36.4
118.3
75
23
L04AD02
ATC
tacrolimus; systemic
41.5
116.2
71
19
UJK12
NOMESCO Finland
Peroral cholangioscopy
1272.3
113.9
108
*
J01MA12
ATC
levofloxacin; systemic
6.2
113.8
269
644
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
61.7
110.8
62
11
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
50.2
109.7
64
14
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
9.8
108.8
140
174
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
46.8
108.0
64
15
TPH04
NOMESCO Finland
Cathetrisation of vein
5.5
106.4
307
869
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
20.7
103.6
81
44
P01BA02
ATC
hydroxychloroquine; oral
13.0
101.7
104
93
K50.9
ICD-10 Finland
Crohn disease, unspecified
19.7
98.8
79
45
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
524.9
94.7
92
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
30.0
93.8
63
23
L04AD01
ATC
ciclosporin; systemic
20.1
90.1
71
39
Z94.4
ICD-10 Finland
Liver transplant status
206.0
88.5
90
5
ZXE00
NOMESCO Finland
One hour or less
4.6
85.7
442
1898
JN3AD
NOMESCO Finland
Abdominal CT examination
6.0
85.7
185
398
ZX120
NOMESCO Finland
Intravenous
6.7
84.9
156
287
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
125.5
83.1
88
8
JJC00
NOMESCO Finland
Allogenic transplantation of liver
434.2
79.6
78
*
L04AB04
ATC
adalimumab; parenteral
27.8
78.5
54
21
L88
ICPC
Rheumatoid/seropositive arthritis
41.9
77.3
47
12
K74.3
ICD-10 Finland
Primary biliary cirrhosis
287.7
77.1
77
*
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
14.2
77.1
73
57
L01BB02
ATC
mercaptopurine; oral
17.4
77.0
65
41
P01AB01
ATC
metronidazole; oral, rectal
4.2
76.5
429
1909
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
13.4
76.5
75
62
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
48.0
76.4
45
10
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
10.5
76.1
89
96
A07EA02
ATC
hydrocortisone; rectal
12.6
72.7
74
65
H02AB06
ATC
prednisolone; systemic
4.1
71.7
448
2118
J01MA02
ATC
ciprofloxacin; systemic
4.0
71.4
379
1604
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.1
69.2
115
189
WX002
NOMESCO Finland
Sedation and analgesia
4.4
69.0
234
720
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
365.7
67.8
67
*
ZXD10
NOMESCO Finland
Scheduled procedure
3.8
67.2
395
1770
Z2221
NOMESCO Finland
Medical doctor
3.7
63.4
319
1281
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
26.0
62.6
44
18
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
19.1
62.5
50
28
K85.8
ICD-10 Finland
Other acute pancreatitis
31.0
62.0
41
14
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
61.5
418
2023
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
9.0
61.4
80
99
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
27.9
61.2
42
16
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
222.3
60.1
61
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.2
59.7
143
331
K50.0
ICD-10 Finland
Crohn disease of small intestine
13.7
59.5
57
45
K51
ICD-10 Finland
Ulcerative colitis
17.3
59.5
50
31
H02AB07
ATC
prednisone; oral
4.6
59.3
169
451
R50.9
ICD-10 Finland
Fever, unspecified
4.1
59.1
206
639
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
163.7
57.9
60
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
10.6
57.1
65
67
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
107.2
54.7
59
6
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
18.3
52.7
43
25
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
7.5
50.6
77
114
H02AB04
ATC
methylprednisolone; systemic
4.1
50.3
165
485
C10AC01
ATC
colestyramine; oral
10.8
50.2
56
56
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
14.2
46.3
43
32
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
18.5
45.8
37
21
WVA20
NOMESCO Finland
Medicine administration
8.4
45.8
62
80
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.9
44.9
161
501
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
15.8
44.6
39
26
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
454.6
43.7
43
*
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
100.6
43.3
47
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
43.0
352
1789
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.9
42.0
80
149
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
4.6
40.0
104
254
H02AB09
ATC
hydrocortisone; systemic
8.1
39.6
55
73
TK800
NOMESCO Finland
Hemodialysis
10.6
39.3
44
44
N02AX02
ATC
tramadol; systemic, rectal
2.8
39.0
359
1914
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
10.2
39.0
45
47
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
398.1
38.4
38
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.9
38.1
128
378
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.1
38.0
70
126
UJF92
NOMESCO Finland
Capsular endoscopy
9.3
37.9
47
54
L01BA01
ATC
methotrexate; systemic
58.5
37.8
44
8
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
200.5
37.2
38
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
36.6
260
1204
JN4CD
NOMESCO Finland
Very extensive body CT
7.4
36.5
55
80
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.0
36.0
116
332
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
10.5
35.7
40
40
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
70.5
35.4
40
6
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.4
35.2
53
77
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
82.6
35.2
39
5
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.9
35.1
84
191
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.1
34.9
188
746
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
34.7
33
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
+∞
34.7
33
*
K75.4
ICD-10 Finland
Autoimmune hepatitis
342.4
33.2
33
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
47.0
33.1
40
9
JJ5AT, ,
NOMESCO Finland
178.4
33.0
34
*
R94.5
ICD-10 Finland
Abnormal results of liver function studies
10.5
33.0
37
37
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.5
32.7
67
133
JN4AD
NOMESCO Finland
Body CT examination
3.9
32.1
103
293
ZXE40
NOMESCO Finland
More than seven and less than nine hours
7.3
31.8
48
70
L04AA13
ATC
[U] leflunomide
167.4
30.9
32
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
5.9
30.7
57
103
JAH00
NOMESCO Finland
Laparotomy
6.8
30.3
49
77
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
43.3
30.2
37
9
L04AA01
ATC
[U] ciclosporin
43.3
30.2
37
9
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
50.9
28.6
34
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
28.3
148
571
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.7
28.0
68
156
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
7.7
27.8
40
55
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
3.4
27.7
113
376
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
7.1
27.4
42
62
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.4
27.3
56
111
JKA20
NOMESCO Finland
Cholecystectomy
7.8
27.0
38
51
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
53.9
26.4
31
6
M13.9
ICD-10 Finland
Arthritis, unspecified
4.3
26.2
72
182
JJA20
NOMESCO Finland
Open biopsy of liver
75.3
26.0
29
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
3.2
25.9
114
397
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
9.5
25.8
31
34
A02BC02
ATC
pantoprazole; systemic
2.4
25.3
492
3450
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
6.8
25.0
40
62
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
26.5
24.2
33
13
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.8
24.0
57
128
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
37.7
23.2
29
8
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
9.4
23.1
28
31
R4110
NOMESCO Finland
Physiotherapy
2.3
22.7
231
1221
A41.8
ICD-10 Finland
Other specified sepsis
8.6
22.4
29
35
K81.0
ICD-10 Finland
Acute cholecystitis
7.9
22.2
31
41
M05BA04
ATC
alendronic acid; oral
4.0
22.0
66
178
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
21.6
191
947
A41.9
ICD-10 Finland
Sepsis, unspecified
5.5
21.5
43
83
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
24.0
21.4
30
13
L04AC05
ATC
ustekinumab; parenteral
35.0
21.3
27
8
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.2
21.1
59
151
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
21.0
90
307
C03DA01
ATC
spironolactone; oral
3.1
20.9
98
352
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
79.3
20.8
23
*
K92.1
ICD-10 Finland
Melaena
4.4
20.7
54
131
3AC01, ,
NOMESCO Finland
19.0
20.6
31
17
UJF02
NOMESCO Finland
Peroral enteroscopy
26.4
20.6
28
11
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
20.4
175
853
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
49.6
20.3
24
5
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
59.3
20.0
23
*
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
+∞
19.9
19
*
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
4.5
19.8
50
118
M45
ICD-10 Finland
Ankylosing spondylitis
18.4
19.7
30
17
K85
ICD-10 Finland
Acute pancreatitis
8.0
19.7
27
35
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
205.6
19.7
20
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
19.6
287
1737
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
6.0
19.5
35
61
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
56.7
19.0
22
*
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
56.7
19.0
22
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.5
19.0
70
217
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.9
18.8
26
34
WX004
NOMESCO Finland
Patient-controlled sedation
39.6
18.6
23
6
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.1
18.5
40
83
WX419
NOMESCO Finland
Other general anesthesy
14.0
18.4
31
23
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
25.8
18.3
25
10
ZXD05
NOMESCO Finland
Urgent procedure
2.1
17.9
240
1394
K83.3
ICD-10 Finland
Fistula of bile duct
97.6
17.6
19
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.1
17.6
79
276
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
17.6
76
260
XX2RW, ,
NOMESCO Finland
8.0
17.5
24
31
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.7
17.5
41
91
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
17.2
133
616
1370
FHL
Colonoscopy, whole colon
32.4
17.1
22
7
R4190
NOMESCO Finland
Nutritional therapy
3.6
16.9
58
171
K83
ICD-10 Finland
Other diseases of biliary tract
+∞
16.7
16
*
JKD50
NOMESCO Finland
Hepatoportoenterostomy
+∞
16.7
16
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.9
16.7
26
39
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
6.9
16.7
26
39
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
174.0
16.6
17
*
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
48.7
16.1
19
*
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
48.7
16.1
19
*
A07EA01
ATC
prednisolone; oral, rectal
25.2
16.1
22
9
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
61.5
15.8
18
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.2
15.8
66
221
Q44.29
ICD-10 Finland
Atresia of bile ducts
+∞
15.7
15
*
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
87.1
15.6
17
*
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
163.5
15.5
16
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.9
15.5
46
123
K80.8
ICD-10 Finland
Other cholelithiasis
6.9
15.4
24
36
D94
ICPC
Chronic enteritis/ulcerative colitis
16.5
15.3
24
15
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.8
15.3
35
76
Z2446
NOMESCO Finland
Social worker
2.9
15.3
76
281
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.3
15.2
31
61
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
14.7
113
519
Q44.21
ICD-10 Finland
Atresia of extrahepatic bile ducts
+∞
14.6
14
*
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
81.9
14.6
16
*
L04AB01
ATC
etanercept; parenteral
153.1
14.5
15
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.0
14.4
31
64
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.6
14.4
49
144
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
17.4
14.4
22
13
Z3226
NOMESCO Finland
Physiotherapist
2.2
14.2
150
786
N02AA05
ATC
oxycodone; systemic
2.3
14.2
119
567
A02BC01
ATC
omeprazole; systemic
2.0
14.2
195
1128
XW000
NOMESCO Finland
Bone marrow biopsy
4.2
14.2
38
94
C03CA01
ATC
furosemide; systemic
2.1
14.0
169
933
A11CC03
ATC
alfacalcidol; systemic
5.0
13.9
30
62
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
76.7
13.6
15
*
M01CB01
ATC
sodium aurothiomalate; parenteral
+∞
13.6
13
*
WX892
NOMESCO Finland
Monitored bed care
2.8
13.6
71
270
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
16.6
13.5
21
13
1280
FHL
Endoscopic retrograde cholangiography and pancreaticography
142.7
13.5
14
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.7
13.4
43
121
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
13.4
179
1022
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.5
13.4
46
136
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
6.5
13.3
22
35
RD210, ,
NOMESCO Finland
5.1
13.2
28
57
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
13.1
257
1668
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
17.1
13.0
20
12
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.5
12.8
25
47
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
15.8
12.7
20
13
B01AB05
ATC
enoxaparin; parenteral
1.9
12.6
205
1250
A07AA11
ATC
rifaximin; oral
24.8
12.5
17
7
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
132.3
12.5
13
*
256, ,
Kela drug reimbursment
38.3
12.2
15
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.5
12.1
82
355
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
5.8
12.0
22
39
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
47.5
11.9
14
*
A07DA03
ATC
loperamide; oral
4.2
11.7
31
76
WX872
NOMESCO Finland
Intensive care
3.4
11.7
43
133
E0000UV, ,
ATC
1.8
11.7
294
2038
M05BA07
ATC
risedronic acid; oral
5.1
11.5
24
48
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
11.5
11
*
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
121.9
11.5
12
*
R11
ICD-10 Finland
Nausea and vomiting
2.5
11.4
79
345
B99
ICD-10 Finland
Other and unspecified infectious diseases
5.3
11.3
23
45
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.3
11.3
23
45
4AB02, ,
NOMESCO Finland
35.7
11.3
14
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
11.3
118
613
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.0
11.3
24
49
ZX108
NOMESCO Finland
Inhalation
13.0
11.2
19
15
Z93.2
ICD-10 Finland
Ileostomy status
20.4
11.2
16
8
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
8.2
11.2
24
30
WZC30
NOMESCO Finland
Teaching
2.1
11.0
112
576
JN1DM
NOMESCO Finland
Upper part of abdomen very extensive MRI examination with 3 Tesla magnet
44.0
10.9
13
*
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.5
10.9
21
39
K81.9
ICD-10 Finland
Cholecystitis, unspecified
15.8
10.9
17
11
SPAT1255
SPAT
Intravenous administration of medicine
3.0
10.8
49
172
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
10.8
154
894
3042, ,
Kela drug reimbursment
28.5
10.8
14
5
253, ,
Kela drug reimbursment
28.5
10.8
14
5
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
60.9
10.6
12
*
R18
ICD-10 Finland
Ascites
5.4
10.6
21
40
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
10.6
115
605
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
4.7
10.5
24
52
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
14.5
10.5
17
12
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
111.6
10.4
11
*
K83.2
ICD-10 Finland
Perforation of bile duct
111.6
10.4
11
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
10.4
10
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
16.3
10.4
16
10
A07AA09
ATC
vancomycin; oral
9.0
10.3
21
24
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.7
10.3
24
53
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
10.3
100
504
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
10.3
157
930
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
13.4
10.2
17
13
JN4BD
NOMESCO Finland
Extensive body CT
2.4
10.1
75
338
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
40.7
10.0
12
*
L04AB06
ATC
golimumab; parenteral
40.7
10.0
12
*
Z3231
NOMESCO Finland
Registered nurse
1.8
10.0
198
1270
J01DB01
ATC
cefalexin; oral
1.9
9.9
574
4923
WW500
NOMESCO Finland
Blood transfusion
3.3
9.9
37
116
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
26.4
9.8
13
5
4AA12, ,
NOMESCO Finland
20.4
9.8
14
7
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
55.8
9.7
11
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
9.7
44
155
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
8.5
9.6
20
24
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
11.6
9.6
17
15
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
9.3
9.6
19
21
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.2
9.5
38
124
JK3NT
NOMESCO Finland
Percutaneous transhepatic dilatation of bileducts
101.4
9.4
10
*
Q44.20
ICD-10 Finland
Atresia of intrahepatic bile ducts
+∞
9.4
9
*
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
+∞
9.4
9
*
5714X
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ALIA SEU NUD]
+∞
9.4
9
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
7.1
9.4
22
32
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
22.0
9.4
13
6
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.6
9.3
30
85
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.9
9.3
43
153
WX882
NOMESCO Finland
High dependency care
3.5
9.3
32
95
XX3DW
NOMESCO Finland
Time consuming IT work
2.3
9.2
76
358
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
13.9
9.2
15
11
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.7
9.2
29
81
E86
ICD-10 Finland
Volume depletion
4.9
9.1
20
42
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
9.2
9.1
18
20
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
9.1
80
388
6611
FHL
Needle biopsy in the operating room
37.2
9.0
11
*
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
18.9
9.0
13
7
RS220, ,
NOMESCO Finland
6.9
8.9
21
31
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
4.8
8.9
20
43
TJF80
NOMESCO Finland
Ostomy education
8.8
8.8
18
21
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.1
8.7
36
120
K83.4
ICD-10 Finland
Spasm of sphincter of Oddi
50.6
8.7
10
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
8.6
73
348
D99
ICPC
Disease digestive system other
8.4
8.6
18
22
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
7.1
8.6
20
29
B03BA03
ATC
hydroxocobalamin; parenteral
3.1
8.6
36
121
H26.3
ICD-10 Finland
Drug-induced cataract
16.5
8.6
13
8
Z94.0
ICD-10 Finland
Kidney transplant status
7.5
8.5
19
26
K29.7
ICD-10 Finland
Gastritis, unspecified
3.5
8.4
29
86
JL5BM
NOMESCO Finland
Bile and pancreas ducts MRI examination with 3 Tesla magnet
91.1
8.4
9
*
UJK52
NOMESCO Finland
Endoscopy of biliary tract in connection with endoscopic retrograde cholangiopancreatography
91.1
8.4
9
*
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
91.1
8.4
9
*
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
6.8
8.4
20
30
JFF10
NOMESCO Finland
Loop enterostomy
13.0
8.4
14
11
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
+∞
8.3
8
*
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
8.3
8
*
C24.00
ICD-10 Finland
Hepatic duct
+∞
8.3
8
*
L04AA10
ATC
[U] sirolimus
+∞
8.3
8
*
UJD02
NOMESCO Finland
Gastroscopy
2.9
8.3
38
134
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.1
8.3
35
118
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.4
8.3
30
92
B01AB04
ATC
dalteparin; parenteral
3.1
8.1
34
114
WW200
NOMESCO Finland
Immunization
3.8
8.1
24
64
C07AG02
ATC
carvedilol; oral
2.7
8.1
42
159
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
11.9
8.1
14
12
D97
ICPC
Liver disease NOS
11.9
8.1
14
12
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
33.8
8.1
10
*
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
17.4
8.1
12
7
K85.1
ICD-10 Finland
Biliary acute pancreatitis
17.4
8.1
12
7
UJG02
NOMESCO Finland
Proctoscopy
4.2
8.0
21
51
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
22.3
8.0
11
5
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
7.9
65
306
UJF30, ,
SPAT
7.9
7.9
17
22
K86.2
ICD-10 Finland
Cyst of pancreas
8.6
7.8
16
19
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.3
7.8
20
48
K92.0
ICD-10 Finland
Haematemesis
4.0
7.8
22
57
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
15.2
7.7
12
8
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
45.5
7.7
9
*
130
Kela drug reimbursment
Malignant tumour
2.3
7.6
56
251
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.3
7.6
28
87
JFF13
NOMESCO Finland
Terminal enterostomy
25.3
7.6
10
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
6.3
7.6
19
31
J05AB11
ATC
valaciclovir; oral
1.9
7.5
99
555
M06
ICD-10 Finland
Other rheumatoid arthritis
80.9
7.4
8
*
57505
ICD-8 Finland
Cholecystitis and cholangitis, without mention of calculus, Cholangitis alia sive NUD
80.9
7.4
8
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
7.4
46
191
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
13.5
7.4
12
9
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.2
7.4
61
288
K56.0
ICD-10 Finland
Paralytic ileus
9.5
7.3
14
15
4AA33, ,
NOMESCO Finland
+∞
7.3
7
*
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
7.3
7
*
K73.89
ICD-10 Finland
Other long-term hepatitis, not classified differently
+∞
7.3
7
*
8140/3-C23.9
ICD-O-3
Adenocarcinoma, NOS, of gallbladder
+∞
7.3
7
*
5739X
ICD-9 Finland
Other disorders of liver, Unspecified disorder of liver
+∞
7.3
7
*
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
7.3
7
*
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
+∞
7.3
7
*
Q44.3
ICD-10 Finland
Congenital stenosis and stricture of bile ducts
+∞
7.3
7
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
7.3
7
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
7.3
287
2162
M05BX04
ATC
denosumab; parenteral
2.8
7.2
35
128
K74.0
ICD-10 Finland
Hepatic fibrosis
20.3
7.1
10
5
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
8.0
7.1
15
19
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
8.0
7.1
15
19
N17.8
ICD-10 Finland
Other acute renal failure
8.0
7.1
15
19
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
3.8
7.1
21
56
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
12.2
7.1
12
10
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
7.1
76
397
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
10.2
7.1
13
13
D98
ICPC
Cholecystitis/cholelithiasis
10.2
7.1
13
13
L29.9
ICD-10 Finland
Pruritus, unspecified
3.5
7.0
24
71
B34.9
ICD-10 Finland
Viral infection, unspecified
3.0
7.0
31
108
S62.6
ICD-10 Finland
Fracture of other finger
0.0
6.9
*
172
TQW99
NOMESCO Finland
Other minor procedure on skin
2.7
6.9
36
137
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
13.9
6.9
11
8
J04AB02
ATC
rifampicin; systemic
6.8
6.8
16
24
A06AC51
ATC
ispaghula, combinations; oral
2.7
6.8
35
132
TNG10
NOMESCO Finland
Puncture of knee
11.1
6.8
12
11
L04AA05
ATC
[U] tacrolimus
40.5
6.8
8
*
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
40.5
6.8
8
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.5
6.7
23
68
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
6.7
102
599
L04AA33
ATC
[U] vedolizumab
22.8
6.7
9
*
PAW37
NOMESCO Finland
Biopsy of temporal artery
22.8
6.7
9
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
6.7
57
273
WX720
NOMESCO Finland
Own respiration
2.7
6.6
36
140
K86.1
ICD-10 Finland
Other chronic pancreatitis
7.9
6.6
14
18
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
6.6
40
164
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.3
6.6
48
215
B01AB10
ATC
tinzaparin; parenteral
2.1
6.6
65
330
L04AA11
ATC
[U] etanercept
70.5
6.4
7
*
JL5CM
NOMESCO Finland
Bile and pancreas ducts extensive MRI examination with 3 Tesla magnet
70.5
6.4
7
*
5714B
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ACTIVA (HBSAG-)]
70.5
6.4
7
*
C24.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of biliary tract
70.5
6.4
7
*
M01CB03
ATC
auranofin; oral
70.5
6.4
7
*
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
14.5
6.4
10
7
B80
ICPC
Iron deficiency anaemia
3.6
6.4
20
56
A10AB05
ATC
insulin aspart; parenteral
2.1
6.3
57
279
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
11.2
6.3
11
10
K80.4
ICD-10 Finland
Calculus of bile duct with cholecystitis
9.4
6.3
12
13
K90.0
ICD-10 Finland
Coeliac disease
3.1
6.3
26
87
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
18.2
6.3
9
5
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
18.2
6.3
9
5
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
6.3
45
915
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
6.3
41
175
B07.9
ICD-10 Finland
Verruca simplex
2.8
6.3
31
115
T86.4
ICD-10 Finland
Liver transplant failure and rejection
+∞
6.3
6
*
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
6.3
6
*
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
7.1
6.2
14
20
JFH10
NOMESCO Finland
Total colectomy and ileostomy
26.9
6.2
8
*
8160/3-C22.1
ICD-O-3
Cholangiocarcinoma of intrahepatic bile duct
26.9
6.2
8
*
K56.7
ICD-10 Finland
Ileus, unspecified
4.0
6.2
17
43
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.0
6.2
26
88
S01AD03
ATC
aciclovir; ophthalmic
2.9
6.1
27
94
A02BC05
ATC
esomeprazole; systemic
1.5
6.1
253
1909
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
6.1
79
441
J01XX08
ATC
linezolid; systemic
8.7
6.1
12
14
TQW40
NOMESCO Finland
Remowal of suture of skin
2.2
6.0
47
217
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
423
620
15.65
314.41
13.0
2.8
10.51
8.48
umol/l
0.86
403
541
238
41
87.31
307.65
1.8
1.2
326.56
98.00
titre
—
96
5
306
156
34.00
307.65
2.7
1.5
294.55
168.00
titre
—
11
5
433
198
55.46
307.65
7.5
3.2
61.30
1539.09
u/ml
0.99
401
168
344
91
73.17
307.65
3.2
1.5
0.82
0.66
g/l
0.48
310
70
459
417
29.91
307.65
4.6
2.4
12.15
9.94
g/l
16.04
446
378
474
501
27.05
307.65
7.1
2.4
0.21
0.22
g/l
2.40
467
471
434
337
32.11
307.65
3.2
1.7
1.34
1.28
g/l
0.19
421
309
506
472
35.81
307.65
7.8
4.2
2.92
16.45
ug/l
0.86
401
387
413
144
68.24
307.65
2.8
1.2
70.79
65.00
titre
0.16
38
12
322
46
128.47
307.65
2.7
1.3
—
—
—
0
0
227
83
39.94
307.65
7.3
4.8
37.36
3259.60
u/ml
0.56
209
78
370
512
14.17
283.17
6.4
2.5
46.52
125.77
u/l
0.40
361
435
439
774
13.47
278.50
5.4
2.5
177.82
121.56
ug/g
2.66
420
628
654
2129
31.30
238.38
20.5
5.0
35.70
36.37
g/l
2.61
649
1998
525
1371
12.22
229.37
17.8
4.1
95.33
93.00
%
1.34
518
1340
607
1891
17.33
225.42
16.2
3.2
39.82
32.00
u/l
4.69
595
1802
622
2217
16.84
194.86
20.9
10.7
1.11
1.18
inr
1.83
205
664
459
1227
8.92
187.31
3.2
1.5
2.57
2.21
g/l
4.52
424
746
135
81
20.40
166.65
1.2
1.1
1.56
1.44
g/l
2.00
125
74
322
675
7.97
162.82
3.3
2.5
22.58
23.46
%
0.40
289
596
578
2203
10.19
157.18
5.3
2.3
75.09
75.23
nmol/l
0.04
568
1992
147
119
15.36
154.58
7.4
7.4
644.74
346.57
iu/ml
0.53
31
23
598
2461
10.65
146.63
17.3
5.6
0.74
0.67
%
2.37
590
2300
330
785
7.05
144.85
3.3
2.4
12.73
13.87
umol/l
1.61
321
737
603
2548
10.69
142.21
17.5
5.5
2.99
2.89
%
0.51
595
2388
605
2567
10.82
142.00
17.9
5.8
8.91
8.50
%
2.53
598
2414
313
725
6.99
140.65
3.4
2.4
2.42
2.39
g/l
0.45
306
679
88
29
34.55
136.21
1.1
1.1
—
—
—
0
0
624
2809
11.99
135.12
17.8
5.9
0.19
0.19
e9/l
0.04
594
2450
604
2658
10.11
132.89
17.6
5.6
29.01
29.31
%
0.28
597
2508
620
2801
11.39
132.73
17.5
5.5
1.80
2.00
e9/l
3.11
591
2475
599
2626
9.73
131.90
17.0
5.4
56.18
55.94
%
0.19
593
2477
464
1673
6.23
124.70
6.5
2.5
75.12
59.75
u/l
1.07
452
1565
206
349
7.94
124.09
2.5
1.6
—
—
—
0
0
232
456
7.11
121.15
15.2
8.7
7.59
8.10
mmol/l
0.58
224
438
637
3154
12.01
117.44
21.6
8.9
3.74
4.00
e9/l
2.55
612
2729
563
2502
7.31
116.00
13.8
7.5
1.21
1.22
mmol/l
0.38
499
2166
101
74
15.77
111.38
1.4
1.3
—
—
—
0
0
525
2309
6.05
105.75
12.3
6.9
1.22
1.22
mmol/l
0.02
510
2124
362
1244
4.94
97.35
4.2
2.2
3.03
2.98
mg/l
0.12
338
1068
124
161
9.14
92.58
1.5
1.5
—
—
—
0
0
593
3081
6.96
92.57
12.8
5.1
6.30
6.60
mmol/l
3.01
582
2874
115
137
9.84
91.83
1.6
1.6
120.35
101.53
u/ml
0.95
17
19
120
153
9.25
90.85
1.5
1.5
389.55
229.96
u/ml
2.23
69
81
91
85
12.15
86.19
6.8
2.5
30.44
7.62
umol/l
4.32
83
61
665
3979
13.74
84.74
12.6
3.3
16.95
10.56
mm/h
18.84
655
3661
104
123
9.75
83.27
6.7
3.1
35.39
35.76
umol/l
0.06
97
111
124
193
7.59
78.86
1.3
1.3
—
—
—
0
0
90
101
10.07
74.76
4.6
4.4
1002.67
2371.58
u/ml
—
9
12
97
122
9.07
73.80
1.9
1.5
0.02
0.03
iu/ml
0.38
29
18
648
4024
8.93
72.02
17.2
3.0
125.13
44.68
u/l
27.95
641
3812
215
617
4.58
69.60
11.7
7.7
104.93
104.14
mmol/l
1.53
215
617
61
42
15.81
68.95
3.6
1.5
0.82
1.09
g/l
3.06
61
42
481
2438
4.09
68.32
4.7
2.8
110.39
113.51
ug/l
0.11
467
2267
324
1268
3.89
67.79
4.1
2.4
—
—
—
0
0
189
507
4.73
66.40
3.2
5.0
225.30
234.28
u/l
0.60
183
488
65
55
12.92
65.21
1.5
1.4
—
—
—
0
0
480
2488
3.94
64.55
4.7
2.6
—
—
—
0
0
223
701
4.20
63.29
11.1
7.1
1.09
1.09
mmol/l
0.06
218
656
58
43
14.61
62.87
1.1
1.0
312.92
293.39
mg/l
0.62
49
36
39
16
25.75
55.29
1.1
1.1
—
—
—
0
0
48
34
15.08
53.23
2.0
1.4
3.11
4.77
u/l
0.35
37
29
342
1571
3.30
52.57
4.8
3.1
130.86
93.18
e6/l
0.12
283
1199
371
1819
3.20
50.48
5.8
3.6
15.63
103.72
e6/l
2.98
292
1283
313
1423
3.16
47.98
4.9
3.0
0.24
0.44
e6/l
2.01
261
1065
259
1055
3.31
47.85
3.5
2.4
5.55
5.81
e6/l
0.08
240
942
173
544
3.89
47.79
4.6
3.7
1.88
1.74
%
0.78
163
502
362
1837
3.00
44.87
5.0
3.1
—
—
—
0
0
94
192
5.50
44.72
2.1
2.2
1.28
1.47
g/l
1.06
82
171
59
81
7.86
41.28
5.1
3.4
55.78
56.02
%
0.04
59
81
213
837
3.22
40.91
3.8
2.9
2.80
2.28
e6/l
0.29
135
442
134
393
3.98
40.43
3.5
3.4
70.48
72.72
e9/l
0.28
101
306
38
29
13.80
40.25
6.9
1.3
23.13
32.97
umol/l
1.87
38
29
153
502
3.62
39.09
3.6
3.2
—
—
—
0
0
203
794
3.19
39.09
2.5
1.9
—
—
—
0
0
91
207
4.90
38.09
6.5
4.1
90.69
91.34
%
0.06
91
200
134
413
3.77
37.49
3.1
2.3
67.65
70.95
ml/min/173m2
0.26
52
164
156
533
3.48
37.32
10.5
5.4
0.85
1.80
mmol/l
2.16
138
439
157
539
3.46
37.27
10.5
5.3
5.77
5.82
kpa
0.26
152
531
71
132
5.87
37.22
1.7
1.2
—
—
—
0
0
55
79
7.47
36.94
5.2
2.9
4.08
4.34
e9/l
0.27
55
79
211
875
3.02
36.38
3.7
2.8
0.66
1.10
e6/l
1.43
133
479
149
525
3.33
33.69
2.9
2.0
338.05
366.04
nmol/l
1.00
143
487
51
80
6.80
31.56
1.4
1.1
86.67
—
titre
—
6
0
116
363
3.63
31.45
5.3
4.0
1.23
1.23
mmol/l
0.07
110
317
348
1986
2.49
30.71
2.4
1.9
94.25
97.30
pmol/l
0.52
205
1009
256
1271
2.60
30.37
4.5
2.7
2526.37
6631.88
umol/l
1.30
244
1122
37
42
9.24
30.05
1.4
1.2
—
—
—
0
0
196
857
2.79
29.92
2.2
1.8
1.47
1.45
%
0.17
170
775
690
5714
13.14
28.84
47.8
11.9
18.30
22.30
mg/l
4.44
664
4321
143
555
2.98
27.00
2.5
1.8
—
—
—
0
0
143
558
2.96
26.72
2.5
1.9
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
58
125
4.97
25.69
3.9
5.3
0.25
0.35
u/ml
1.21
26
65
90
271
3.66
25.66
2.0
1.7
—
—
—
0
0
638
5100
3.75
25.05
50.4
14.7
14.28
14.50
%
0.87
638
5026
36
50
7.54
24.80
1.0
1.1
—
—
—
0
0
82
241
3.72
24.19
16.5
13.9
—
—
—
0
0
57
133
4.58
22.92
1.9
1.6
—
—
—
0
0
393
2588
2.18
22.29
4.5
3.2
0.00
0.00
estimate
0.50
105
501
392
2593
2.16
21.80
6.2
4.4
0.00
0.00
estimate
0.50
104
480
394
2618
2.15
21.58
4.5
3.2
0.00
0.01
estimate
0.50
104
453
640
5263
3.45
21.08
35.7
10.8
88.89
86.35
ml/min/173m2
1.83
590
4256
44
89
5.21
20.91
1.0
1.1
—
—
—
0
0
101
371
3.01
20.75
8.2
4.8
96.65
78.04
ng/l
0.90
96
339
170
814
2.44
20.69
2.0
1.6
1218.74
1180.85
nmol/l
0.19
143
607
58
154
4.02
19.69
1.7
1.4
—
—
—
0
0
281
1702
2.09
18.97
4.2
3.2
2.34
2.36
mmol/l
1.87
259
1518
30
19
16.43
18.94
3.8
6.1
8.65
8.51
mg/l
0.03
24
19
119
505
2.63
18.54
14.4
10.1
0.09
1.16
mmol/l
1.83
98
411
204
1124
2.15
17.41
2.1
1.5
19.33
20.97
nmol/l
0.89
194
961
238
1414
2.03
16.46
1.5
1.3
1.00
1.18
u/ml
0.34
56
378
212
1211
2.08
16.30
3.6
2.1
1.79
1.16
mg/l
1.29
175
916
54
158
3.62
15.95
1.6
1.5
218.12
314.35
ug/g
2.10
35
98
56
168
3.54
15.94
1.9
1.8
1.94
1.53
ug/l
0.21
50
154
22
10
22.66
15.62
4.6
3.2
—
—
—
0
0
23
38
6.22
13.47
2.2
2.4
—
—
—
0
0
74
290
2.73
13.35
18.7
11.7
0.60
0.68
%
1.12
74
290
43
122
3.69
13.29
1.8
1.3
—
—
—
0
0
642
5594
2.73
13.16
6.3
4.1
4.57
4.72
mmol/l
3.70
627
5245
73
292
2.67
12.65
18.7
11.6
1.25
1.46
%
1.67
73
292
33
80
4.28
12.63
2.4
1.6
6173.62
20332.22
e6/l
1.19
21
58
43
128
3.51
12.38
1.3
1.1
7.38
3.28
u/ml
—
6
17
172
1001
1.95
12.07
1.8
1.7
438.15
4739774.29
pmol/l
0.50
151
844
99
472
2.28
11.74
11.2
5.0
5.14
4.77
kpa
0.79
94
462
36
100
3.74
11.48
1.2
1.1
—
—
—
0
0
49
170
3.02
11.03
6.9
7.9
1.64
1.54
%
0.14
49
160
32
86
3.85
10.69
1.8
1.5
—
—
—
0
0
27
64
4.35
10.64
1.3
1.5
—
—
—
0
0
16
10
16.33
10.38
2.0
1.4
—
—
—
0
0
32
88
3.76
10.36
1.7
1.3
—
—
—
0
0
22
28
8.07
10.17
1.5
1.3
63.67
56.90
%
—
9
21
38
120
3.29
10.01
2.2
2.0
—
—
—
0
0
510
4221
1.76
9.96
3.7
3.3
—
—
—
0
0
69
302
2.42
9.91
1.6
1.5
—
—
—
0
0
193
1231
1.78
9.91
2.7
3.4
1193.82
949.17
ng/l
0.51
170
1038
17
14
12.41
9.89
2.5
1.4
11333.78
9116.71
e6/l
—
9
7
18
17
10.83
9.82
1.6
1.1
38.54
39.30
%
—
8
10
43
149
3.01
9.72
2.4
2.1
—
—
—
0
0
146
862
1.88
9.61
3.4
2.9
2.48
2.44
mmol/l
3.28
135
759
54
223
2.54
8.78
1.9
1.7
—
—
—
0
0
153
943
1.80
8.69
3.9
3.7
62.72
390.63
ng/l
3.19
116
668
18
22
8.37
8.62
1.1
1.1
1251.50
1472.82
miu/ml
0.40
18
22
261
1868
1.63
8.52
4.2
3.3
34.06
54.47
ng/l
0.46
179
1199
26
71
3.76
8.52
1.9
1.5
—
—
—
0
0
35
117
3.10
8.42
1.8
1.3
—
—
—
0
0
35
117
3.10
8.42
1.8
1.3
—
—
—
0
0
39
139
2.91
8.41
2.4
1.7
—
—
—
0
0
39
140
2.89
8.30
1.9
1.7
—
—
—
0
0
32
103
3.21
8.20
2.0
1.7
—
—
—
0
0
32
103
3.21
8.20
2.0
1.7
—
—
—
0
0
26
74
3.61
8.04
1.7
1.4
—
—
—
0
0
26
74
3.61
8.04
1.7
1.4
—
—
—
0
0
26
74
3.61
8.04
1.7
1.4
—
—
—
0
0
201
1363
1.67
8.03
5.1
3.3
0.00
0.01
estimate
0.88
99
471
16
19
8.59
7.84
1.2
1.6
—
—
—
0
0
276
2036
1.59
7.78
4.6
3.2
—
—
—
0
0
215
1497
1.63
7.69
2.0
1.6
1.26
1.44
mmol/l
2.89
203
1287
30
98
3.15
7.52
4.8
2.5
15.58
16.46
%
0.55
15
54
25
73
3.51
7.45
1.6
1.4
—
—
—
0
0
25
73
3.51
7.45
1.6
1.4
—
—
—
0
0
13
12
11.01
7.32
1.0
1.1
—
—
—
0
0
25
74
3.47
7.31
1.6
1.4
—
—
—
0
0
13
13
10.16
7.05
5.6
6.5
54.65
47.27
%
0.36
13
13
35
130
2.78
7.03
2.4
3.7
38.74
89.87
mg/l
0.54
24
106
690
6532
4.30
6.94
62.9
17.6
39.26
41.51
%
2.52
668
6164
22
62
3.63
6.91
2.0
1.6
—
—
—
0
0
18
44
4.17
6.85
1.8
3.2
—
—
—
0
0
34
130
2.70
6.48
2.4
3.7
28.22
29.95
mg/l
0.19
23
105
20
57
3.58
6.20
2.0
1.8
31.15
32.58
pg
0.74
20
57
41
176
2.41
6.19
1.1
1.1
—
—
—
0
0
23
75
3.14
5.81
2.3
1.7
—
—
—
0
0
23
75
3.14
5.81
2.3
1.7
—
—
—
0
0
620
5677
1.79
5.80
5.7
4.5
2.62
2.83
mmol/l
9.03
600
5284
40
176
2.35
5.73
1.1
1.1
—
—
—
0
0
28
104
2.76
5.66
1.8
1.5
—
—
—
0
0
15
28
5.45
5.56
1.1
1.0
—
—
—
0
0
15
28
5.45
5.56
1.1
1.0
—
—
—
0
0
42
192
2.26
5.52
2.2
1.8
—
—
—
0
0
45
212
2.20
5.51
1.2
1.3
281.37
221.21
miu/ml
0.45
17
99
12
17
7.16
5.45
1.4
1.1
10.70
9.11
ug/l
0.42
12
17
592
5376
1.65
5.43
5.0
3.7
1.19
1.31
mmol/l
5.69
573
4995
15
29
5.26
5.41
1.1
1.0
—
—
—
0
0
15
29
5.26
5.41
1.1
1.0
—
—
—
0
0
15
29
5.26
5.41
1.1
1.0
—
—
—
0
0
73
415
1.85
5.33
12.8
5.1
0.62
1.70
mmol/l
1.32
52
304
5
0
+∞
5.21
1.4
0.0
1.84
—
mg/l
—
5
0
27
103
2.69
5.20
1.5
1.8
—
—
—
0
0
608
5573
1.68
5.20
5.5
4.0
1.52
1.44
mmol/l
4.30
592
5196
18
54
3.39
5.19
1.2
1.1
—
—
—
0
0
15
40
3.81
5.11
1.4
1.2
—
—
—
0
0
39
179
2.25
5.10
1.9
1.7
—
—
—
0
0
8
6
13.47
5.09
1.4
1.0
—
—
—
0
0
18
55
3.33
5.05
1.2
1.1
—
—
—
0
0
9
9
10.11
5.03
3.4
3.0
—
—
—
0
0
34
148
2.36
5.01
2.3
2.7
—
—
—
0
0
14
28
5.08
4.96
2.5
3.0
1420.79
706.89
u/ml
0.88
14
28
15
42
3.63
4.79
1.0
1.5
—
—
—
0
0
22
85
2.64
4.17
1.5
1.6
—
—
—
0
0
14
42
3.38
4.06
1.2
1.6
—
—
—
0
0
213
1659
1.41
4.03
3.7
3.3
7.23
8.09
mmol/l
1.72
198
1428
12
27
4.50
3.95
1.8
1.3
—
—
—
0
0
12
27
4.50
3.95
1.9
1.3
—
—
—
0
0
190
1482
1.39
3.50
2.3
2.1
173.81
215.95
u/l
0.28
185
1404
18
70
2.61
3.40
1.7
1.8
—
—
—
0
0
11
28
3.97
3.30
1.1
1.1
—
—
—
0
0
122
892
1.45
3.23
1.3
1.2
59.07
22.05
iu/ml
1.17
43
265
116
843
1.45
3.17
1.4
1.2
17.95
2.02
u/ml
1.29
43
325
55
338
1.68
3.14
1.2
1.3
—
—
—
0
0
10
25
4.04
3.09
1.1
1.1
—
—
—
0
0
10
25
4.04
3.09
1.4
1.6
—
—
—
0
0
15
56
2.72
3.07
2.5
2.4
—
—
—
0
0
8
16
5.04
3.05
1.1
1.3
—
—
—
0
0
14
51
2.78
3.00
3.0
2.1
—
—
—
0
0
21
94
2.27
2.99
1.2
1.4
—
—
—
0
0
10
27
3.74
2.89
5.5
3.3
—
—
—
0
0
6
9
6.71
2.87
1.3
1.9
—
—
—
0
0
8
19
4.25
2.68
1.9
2.0
118.38
107.96
ug/l
—
8
19
41
244
1.72
2.66
10.7
4.2
0.72
0.65
%
0.54
41
244
16
67
2.42
2.65
1.0
1.3
—
—
—
0
0
9
26
3.49
2.49
1.8
1.3
—
—
—
0
0
9
26
3.49
2.49
1.8
1.3
—
—
—
0
0
15
64
2.37
2.40
1.4
1.4
—
—
—
0
0
9
29
3.13
2.23
1.2
1.7
—
—
—
0
0
9
29
3.13
2.23
1.2
1.7
—
—
—
0
0
5
9
5.59
2.21
1.2
1.3
—
—
—
0
0
57
813
0.67
2.16
2.7
2.6
0.74
0.69
ug/l
0.11
34
456
472
4351
1.26
2.16
4.3
3.9
14.73
14.64
pmol/l
0.32
439
3992
553
5199
1.30
2.14
5.0
4.5
1.96
2.11
mu/l
0.27
522
4810
18
88
2.07
2.13
1.1
1.1
—
—
—
0
0
19
95
2.03
2.12
4.9
2.9
1.36
1.49
mmol/l
0.39
19
95
20
102
1.99
2.12
1.3
1.1
5.55
2.49
u/ml
—
6
47
16
75
2.16
2.10
1.4
1.7
—
—
—
0
0
5
10
5.03
2.07
5.0
2.7
218.80
5856.10
u/l
—
5
10
178
1477
1.27
2.04
4.2
3.9
12.46
10.08
mg/mmol
0.14
118
945
12
50
2.42
2.03
1.4
1.1
—
—
—
0
0
8
26
3.10
2.02
2.3
1.7
16.88
13.12
u/l
—
8
26
12
51
2.38
1.96
2.8
2.5
4.06
3.98
mmol/l
0.21
12
51
16
78
2.08
1.92
1.5
1.3
3.20
5.70
u/ml
—
10
23
12
52
2.33
1.88
1.2
1.6
—
—
—
0
0
12
52
2.33
1.88
1.3
1.6
—
—
—
0
0
12
52
2.33
1.88
1.2
1.6
—
—
—
0
0
7
22
3.20
1.88
1.3
1.8
—
—
—
0
0
7
22
3.20
1.88
1.3
1.8
—
—
—
0
0
7
22
3.20
1.88
1.3
1.8
—
—
—
0
0
7
22
3.20
1.88
1.4
1.7
—
—
—
0
0
14
66
2.14
1.83
1.3
1.8
—
—
—
0
0
45
648
0.67
1.81
1.4
1.7
—
—
—
0
0
17
87
1.98
1.81
5.2
3.1
7.55
7.49
mmol/l
0.03
17
87
7
23
3.06
1.80
1.4
1.7
—
—
—
0
0
8
30
2.69
1.72
2.1
3.0
—
—
—
0
0
8
30
2.69
1.72
1.3
1.2
—
—
—
0
0
8
30
2.69
1.72
2.1
3.0
—
—
—
0
0
8
30
2.69
1.72
2.3
2.8
43287.50
36316.83
ug/l
—
8
30
6
20
3.02
1.58
1.8
1.9
—
—
—
0
0
88
1104
0.77
1.53
3.4
3.7
19.75
21.62
%
0.68
33
435
11
51
2.18
1.51
2.9
2.5
105.27
105.43
mmol/l
0.04
11
51
29
187
1.57
1.48
1.3
1.3
—
—
—
0
0
564
5390
1.24
1.44
4.4
4.1
5.86
5.86
mmol/l
0.01
531
4956
6
22
2.74
1.43
1.2
1.3
—
—
—
0
0
9
179
0.50
1.41
1.6
1.4
—
—
—
0
0
5
18
2.79
1.28
1.4
1.6
—
—
—
0
0
8
37
2.18
1.21
1.5
1.6
—
—
—
0
0
17
101
1.70
1.20
20.2
6.0
62.70
64.05
%
0.08
17
101
50
379
1.34
1.16
2.4
2.4
24.83
16.31
au/ml
—
6
28
31
217
1.45
1.13
1.4
1.5
8.44
8.06
u/l
0.03
24
174
531
5084
1.18
1.13
6.4
5.1
38.10
39.23
mmol/mol
1.74
509
4763
17
104
1.65
1.10
1.2
1.1
—
—
—
0
0
18
113
1.61
1.06
2.1
1.8
—
—
—
0
0
27
188
1.45
1.03
1.2
1.1
—
—
—
0
0
9
49
1.85
0.99
2.1
3.9
—
—
—
0
0
25
173
1.46
0.98
1.7
1.7
—
—
—
0
0
7
36
1.95
0.97
1.1
1.3
—
—
—
0
0
47
594
0.78
0.91
8.7
6.2
—
—
—
0
0
17
110
1.56
0.91
5.2
3.4
25.73
23.60
mg/l
0.08
12
66
8
45
1.79
0.84
1.8
1.4
3.06
3.16
mg/l
—
8
45
0
28
0.00
0.76
0.0
1.1
—
20.01
—
0
21
27
356
0.75
0.74
2.3
1.9
—
—
—
0
0
38
299
1.29
0.74
1.3
1.5
32.24
24.22
iu/l
0.54
30
246
7
117
0.59
0.68
2.0
1.7
—
—
—
0
0
36
450
0.79
0.68
2.3
2.0
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
52
432
1.22
0.66
1.1
1.3
143.82
158.32
iu/ml
0.07
15
186
17
122
1.40
0.60
2.3
2.5
52.21
111.62
ug/min
—
8
82
18
131
1.38
0.59
1.2
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
8
53
1.52
0.58
1.0
1.2
—
—
—
0
0
6
36
1.67
0.56
1.2
1.5
1.64
1.53
g/l
—
6
36
97
872
1.13
0.50
1.5
1.4
—
—
—
0
0
7
47
1.49
0.47
1.3
1.1
1.14
1.29
nmol/l
—
7
41
143
1320
1.10
0.47
1.7
1.6
—
—
—
0
0
23
284
0.80
0.43
1.6
1.5
—
—
—
0
0
5
32
1.57
0.42
1.2
1.3
—
16.60
—
0
5
27
222
1.22
0.41
2.1
2.6
65.40
4466.28
u/l
—
10
96
128
1380
0.91
0.41
3.7
4.0
1.71
1.84
ug/l
0.24
117
1257
15
114
1.32
0.41
1.1
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
28.67
—
0
18
0
18
0.00
0.40
0.0
1.1
—
1.62
—
0
12
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
30
353
0.84
0.37
1.0
1.1
—
—
—
0
0
127
1185
1.09
0.35
5.5
3.3
1.02
1.02
kg/l
0.02
20
154
21
174
1.21
0.31
1.3
1.5
—
—
—
0
0
14
172
0.81
0.27
1.6
1.5
—
—
—
0
0
15
122
1.23
0.27
1.1
1.1
—
11.15
—
0
11
5
75
0.66
0.26
1.0
1.0
—
—
—
0
0
11
87
1.27
0.24
1.1
1.1
—
—
—
0
0
43
389
1.11
0.24
1.8
2.3
1.80
7.33
ug/l
7.19
33
352
6
84
0.71
0.24
1.2
1.3
8.13
7.18
mmol/l
—
6
72
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.13
—
0
6
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
8
101
0.79
0.21
1.5
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.15
—
0
7
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.0
—
2.54
—
0
5
16
136
1.18
0.20
3.6
4.6
4.04
3.83
mmol/l
0.38
16
136
6
49
1.23
0.20
1.3
2.1
19.50
18.50
ug/l
—
6
49
6
50
1.20
0.19
1.0
1.2
—
—
—
0
0
76
804
0.94
0.18
1.9
2.0
—
—
—
0
0
6
76
0.79
0.15
1.5
1.2
2.68
2.96
ug/l
—
6
66
43
401
1.08
0.14
1.5
1.2
128.35
235.39
u/ml
0.85
38
371
85
887
0.95
0.14
2.0
2.1
—
—
—
0
0
67
638
1.06
0.13
3.7
4.2
36.16
31.14
%
3.85
56
438
14
158
0.88
0.12
1.6
1.4
—
—
—
0
0
14
158
0.88
0.12
1.6
1.4
—
—
—
0
0
14
157
0.89
0.11
1.6
1.4
—
—
—
0
0
14
157
0.89
0.11
1.6
1.4
—
—
—
0
0
24
221
1.09
0.11
2.0
1.8
60.83
36.59
nmol/l
2.24
24
212
6
57
1.05
0.08
2.7
3.3
140.17
69.23
u/ml
—
6
57
6
58
1.03
0.08
1.5
1.6
141.28
195.67
pmol/l
—
6
58
23
246
0.93
0.08
2.1
1.8
—
—
—
0
0
9
86
1.05
0.07
1.2
1.6
—
—
—
0
0
9
88
1.02
0.07
2.2
1.9
—
1680.00
—
0
5
15
138
1.09
0.06
1.3
2.1
27.50
213.81
e6/l
—
10
109
15
138
1.09
0.06
1.3
2.0
4.00
7.01
e6/l
—
7
106
14
150
0.93
0.04
1.1
1.2
7.76
3.26
u/ml
—
7
92
14
136
1.03
0.00
1.4
1.5
—
—
—
0
0
14
144
0.97
0.00
1.3
1.9
3.72
3.69
mmol/l
0.05
14
135
16
156
1.03
0.00
1.3
2.0
413.69
442.93
mg/l
0.20
16
147
48
484
0.99
0.00
2.1
2.3
16.64
13.74
nmol/l
1.26
43
452
13
131
0.99
0.00
1.1
1.1
3.28
1.86
u/ml
—
8
82
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
0.43
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
19
190
1.00
-0.00
1.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
11.53
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_CHOLANGI_STRICT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_CHOLANGI_STRICT | 2.908 [2.29, 3.7] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.435 |
During the follow-up period (1.1.1998 — 31.12.2019), 280 out of 1127 females with K11_CHOLANGI_STRICT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_CHOLANGI_STRICT | 2.237 [1.71, 2.93] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 180 out of 971 males with K11_CHOLANGI_STRICT died.
Mortality risk
Mortality risk for people of age
years, who have K11_CHOLANGI_STRICT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.293% | 0.479% |
| 5 | 1.856% | 2.601% |
| 10 | 4.805% | 6.542% |
| 15 | 8.555% | 12.088% |
| 20 | 14.957% | 19.247% |
Relationships between endpoints
↥Index endpoint: K11_CHOLANGI_STRICT – Cholangitis (primary sclerosing, PSC), with reimbursement 202
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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