ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditions
|
302 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
302 |
6. Filter based on genotype QC (FinnGen only) |
297 |
Control definitions (FinnGen only)
- Control exclude
- K11_IBD, K11_CHOLANGI
- Control conditions
- not K11_CHOLANGI_STRICT
and not K11_UC_STRICT
Extra metadata
- First used in FinnGen datafreeze
- DF4
Similar endpoints
↥List of similar endpoints to
Ulcerative colitis (strict) with PSC
based on the number of shared cases.
Similar with more cases:
- IBD (strict) with PSC
- Colitis, primary sclerosing
- Cholangitis (primary sclerosing, PSC), with reimbursement 202
- Cholangitis (primary sclerosing, PSC)
- Ulcerative colitis (strict definition, require KELA)
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 896 | 350 | 542 |
| Only index persons | 876 | 342 | 534 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.02 |
| Only index persons | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 26.31 | 27.84 | 25.12 |
| Only index persons | 26.07 | 27.64 | 25.07 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 297 | 136 | 161 |
| Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | 27.17 | 27.66 | 26.76 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 302
- Matched controls
- 3020
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
+∞
314.5
302
150
K83.0
ICD-10 Finland
Cholangitis
+∞
307.7
302
*
A07EC02
ATC
mesalazine; oral, rectal
5848.4
307.7
290
9
A05AA02
ATC
ursodeoxycholic acid; oral
6606.0
307.7
294
14
K51.5
ICD-10 Finland
Left sided colitis
+∞
307.7
256
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
307.7
302
*
UJF30
NOMESCO Finland
Ileoscopy through colon
60.2
295.6
206
104
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4446.1
283.1
228
*
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
2225.7
273.1
224
*
L04AX01
ATC
azathioprine; systemic
117.8
247.6
129
19
UJF32
NOMESCO Finland
Coloscopy
48.2
239.2
253
292
UJK02
NOMESCO Finland
ERCP
122.1
230.5
119
16
A07EA06
ATC
budesonide; oral, local oral
159.0
222.5
111
11
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
113.8
219.1
114
16
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
32.1
206.4
167
112
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
74.7
196.8
110
23
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
93.4
180.2
96
15
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
60.1
139.2
80
18
K51.8
ICD-10 Finland
Other ulcerative colitis
+∞
137.2
121
*
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
286.5
126.4
121
7
WX404
NOMESCO Finland
Intravenous generell anesthesy
14.2
124.7
197
352
WX402
NOMESCO Finland
General anaesthesia
14.2
124.0
198
358
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
109.1
98
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
11.5
104.5
191
393
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
56.9
83.6
48
10
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
79.8
73
*
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
122.2
77.5
81
9
UJK12
NOMESCO Finland
Peroral cholangioscopy
+∞
74.1
68
*
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
71.8
66
*
P01AB01
ATC
metronidazole; oral, rectal
8.4
68.9
222
751
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.7
67.0
108
181
A07EC01
ATC
sulfasalazine; oral, rectal
11.7
66.8
78
87
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
13.0
66.1
71
70
ZX120
NOMESCO Finland
Intravenous
11.2
66.0
80
94
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.2
65.5
156
392
A07EA02
ATC
hydrocortisone; rectal
164.8
63.7
65
5
ZXE00
NOMESCO Finland
One hour or less
7.6
63.3
218
768
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
711.0
61.0
58
*
TPH04
NOMESCO Finland
Cathetrisation of vein
6.7
58.6
136
328
H02AB07
ATC
prednisone; oral
8.5
57.5
90
144
J01MA12
ATC
levofloxacin; systemic
7.0
55.7
114
242
L04AA06
ATC
mycophenolic acid; systemic
24.7
53.4
39
18
WX002
NOMESCO Finland
Sedation and analgesia
6.7
52.8
112
245
H02AB06
ATC
prednisolone; systemic
6.2
51.1
213
840
ZXD10
NOMESCO Finland
Scheduled procedure
5.7
49.9
188
677
K83.1
ICD-10 Finland
Obstruction of bile duct
122.2
48.5
51
5
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
+∞
47.1
44
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
46.0
43
*
K51
ICD-10 Finland
Ulcerative colitis
509.1
45.5
44
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
10.9
45.3
53
58
Z2221
NOMESCO Finland
Medical doctor
5.2
44.5
155
513
J01MA02
ATC
ciprofloxacin; systemic
4.9
41.3
173
654
JJC00
NOMESCO Finland
Allogenic transplantation of liver
455.3
41.1
40
*
Z94.4
ICD-10 Finland
Liver transplant status
161.9
40.9
42
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
40.5
38
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
442.0
40.1
39
*
L01BB02
ATC
mercaptopurine; oral
157.5
39.8
41
*
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
428.9
39.0
38
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
12.0
38.4
41
39
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
71.2
38.3
43
7
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
94.6
37.9
41
5
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
+∞
37.3
35
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
210.0
36.6
37
*
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
390.2
35.7
35
*
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
35.1
33
*
WVA20
NOMESCO Finland
Medicine administration
13.1
34.9
35
30
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
9.9
34.9
43
50
JN3AD
NOMESCO Finland
Abdominal CT examination
6.0
34.6
72
150
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.6
34.6
48
65
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
34.0
32
*
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
32.9
31
*
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
127.2
32.4
34
*
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
12.2
31.6
33
30
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
347.0
31.4
31
*
127
Kela drug reimbursment
Transplant complication
35.2
31.3
40
13
K76.9
ICD-10 Finland
Liver disease, unspecified
37.1
30.9
39
12
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
321.3
29.3
29
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
11.1
28.8
32
32
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
+∞
28.6
27
*
K74.3
ICD-10 Finland
Primary biliary cirrhosis
86.2
28.3
31
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
27.5
26
*
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
+∞
27.5
26
*
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
27.5
26
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.8
26.2
54
110
H02AB04
ATC
methylprednisolone; systemic
4.8
25.9
68
171
L04AD02
ATC
tacrolimus; systemic
35.6
25.2
32
10
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
141.7
25.0
26
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
73.8
24.2
27
*
TPH07
NOMESCO Finland
Cathetrisation of artery
5.2
23.0
53
119
L04AD01
ATC
ciclosporin; systemic
24.5
22.2
31
14
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
+∞
22.2
21
*
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
22.2
21
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.0
22.1
42
79
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
21.7
157
768
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
9.2
21.3
27
32
R50.9
ICD-10 Finland
Fever, unspecified
3.9
21.1
77
246
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
21.1
20
*
A07EA01
ATC
prednisolone; oral, rectal
+∞
21.1
20
*
JJ5AT, ,
NOMESCO Finland
+∞
20.0
19
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
31.4
20.0
26
9
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
49.5
19.5
23
5
K85.8
ICD-10 Finland
Other acute pancreatitis
49.5
19.5
23
5
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
24.6
19.4
27
12
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.9
19.0
67
208
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
74.8
19.0
21
*
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
101.1
17.8
19
*
JN4CD
NOMESCO Finland
Very extensive body CT
17.3
17.4
27
17
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
18.8
17.3
26
15
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.4
16.8
29
49
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
+∞
16.8
16
*
L04AC05
ATC
ustekinumab; parenteral
95.4
16.7
18
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.5
16.6
34
68
K92.1
ICD-10 Finland
Melaena
7.0
16.5
26
40
3AC01, ,
NOMESCO Finland
50.4
16.2
19
*
C10AC01
ATC
colestyramine; oral
13.3
16.2
28
23
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.5
16.1
33
66
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
15.8
15
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
15.7
137
711
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.1
15.7
48
134
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
30.4
15.4
20
7
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
30.4
15.4
20
7
L04AB04
ATC
adalimumab; parenteral
13.4
15.2
26
21
UJF92
NOMESCO Finland
Capsular endoscopy
33.6
15.0
19
6
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
12.8
14.9
26
22
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
84.3
14.7
16
*
D94
ICPC
Chronic enteritis/ulcerative colitis
157.3
14.6
15
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
14.5
99
450
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.3
14.5
40
103
L04AA01
ATC
[U] ciclosporin
56.1
13.9
16
*
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
56.1
13.9
16
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
35.9
13.6
17
5
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.9
12.8
73
300
N02AX02
ATC
tramadol; systemic, rectal
2.4
12.6
139
786
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
135.4
12.5
13
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
5.8
12.3
23
42
UJF02
NOMESCO Finland
Peroral enteroscopy
31.4
11.8
15
5
1370
FHL
Colonoscopy, whole colon
67.7
11.7
13
*
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
12.5
11.5
20
17
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
124.6
11.5
12
*
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
124.6
11.5
12
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
11.8
11.2
20
18
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
4.2
11.1
31
80
H02AB09
ATC
hydrocortisone; systemic
9.4
11.0
22
25
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
9.4
11.0
22
25
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
5.3
10.7
22
44
WW500
NOMESCO Finland
Blood transfusion
5.7
10.5
20
37
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
113.8
10.5
11
*
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
113.8
10.5
11
*
JFF10
NOMESCO Finland
Loop enterostomy
113.8
10.5
11
*
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
10.5
10
*
253, ,
Kela drug reimbursment
+∞
10.5
10
*
3042, ,
Kela drug reimbursment
+∞
10.5
10
*
K83
ICD-10 Finland
Other diseases of biliary tract
+∞
10.5
10
*
4AA12, ,
NOMESCO Finland
+∞
10.5
10
*
K83.3
ICD-10 Finland
Fistula of bile duct
+∞
10.5
10
*
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
24.4
10.3
14
6
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.9
10.3
31
85
A07DA03
ATC
loperamide; oral
8.9
10.2
21
25
XX2RW, ,
NOMESCO Finland
15.3
10.1
16
11
WX419
NOMESCO Finland
Other general anesthesy
12.8
10.0
17
14
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
9.8
53
210
Z93.2
ICD-10 Finland
Ileostomy status
56.9
9.7
11
*
R4110
NOMESCO Finland
Physiotherapy
2.3
9.6
95
502
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
103.1
9.5
10
*
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
22.5
9.4
13
6
4AB02, ,
NOMESCO Finland
+∞
9.4
9
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.3
9.2
24
59
A02BC01
ATC
omeprazole; systemic
2.3
9.2
82
414
TJF80
NOMESCO Finland
Ostomy education
37.9
9.1
11
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
8.9
77
382
JN4AD
NOMESCO Finland
Body CT examination
3.3
8.9
35
115
M05BA04
ATC
alendronic acid; oral
5.0
8.7
19
40
SPAT1255
SPAT
Intravenous administration of medicine
4.3
8.7
23
57
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.8
8.7
21
33
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
28.4
8.5
11
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
7.1
8.5
20
30
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
+∞
8.4
8
*
JN1DM
NOMESCO Finland
Upper part of abdomen very extensive MRI examination with 3 Tesla magnet
+∞
8.4
8
*
JL5BM
NOMESCO Finland
Bile and pancreas ducts MRI examination with 3 Tesla magnet
+∞
8.4
8
*
256, ,
Kela drug reimbursment
+∞
8.4
8
*
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
8.4
8
*
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
+∞
8.4
8
*
130
Kela drug reimbursment
Malignant tumour
3.7
8.3
27
78
ZXE20
NOMESCO Finland
More than three and less than five hours
2.8
8.3
45
178
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
15.0
8.3
13
9
WX004
NOMESCO Finland
Patient-controlled sedation
34.4
8.1
10
*
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
34.4
8.1
10
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.9
8.1
24
65
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
22.7
8.1
11
5
JAH00
NOMESCO Finland
Laparotomy
8.1
8.0
17
22
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
8.0
120
738
A02BC02
ATC
pantoprazole; systemic
2.0
7.9
191
1387
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
9.8
7.9
15
16
R4190
NOMESCO Finland
Nutritional therapy
3.9
7.8
23
62
B01AB05
ATC
enoxaparin; parenteral
2.2
7.8
82
440
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.4
7.7
16
20
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
19.0
7.7
11
6
M81.9
ICD-10 Finland
Osteoporosis, unspecified
9.2
7.6
15
17
TK800
NOMESCO Finland
Hemodialysis
9.2
7.6
15
17
JKA20
NOMESCO Finland
Cholecystectomy
10.4
7.6
14
14
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
82.0
7.4
8
*
1280
FHL
Endoscopic retrograde cholangiography and pancreaticography
82.0
7.4
8
*
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
+∞
7.3
7
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
+∞
7.3
7
*
M81.8
ICD-10 Finland
Other osteoporosis
30.8
7.2
9
*
D64.9
ICD-10 Finland
Anaemia, unspecified
3.3
7.2
27
86
ZX108
NOMESCO Finland
Inhalation
20.6
7.2
10
5
Z2446
NOMESCO Finland
Social worker
3.0
7.1
32
114
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
7.0
51
233
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
7.0
32
115
XX3DW
NOMESCO Finland
Time consuming IT work
2.7
6.9
38
151
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
17.2
6.8
10
6
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
41.0
6.8
8
*
ZXD05
NOMESCO Finland
Urgent procedure
2.0
6.7
97
581
WX892
NOMESCO Finland
Monitored bed care
3.1
6.7
28
95
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.2
6.7
18
45
WZC30
NOMESCO Finland
Teaching
2.4
6.6
49
225
A07AA11
ATC
rifaximin; oral
71.3
6.4
7
*
JFF13
NOMESCO Finland
Terminal enterostomy
71.3
6.4
7
*
K75.4
ICD-10 Finland
Autoimmune hepatitis
71.3
6.4
7
*
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
71.3
6.4
7
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
71.3
6.4
7
*
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
71.3
6.4
7
*
K85
ICD-10 Finland
Acute pancreatitis
11.4
6.3
11
10
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
6.3
66
351
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.7
6.3
20
57
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
6.3
6
*
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
6.3
6
*
JFH10
NOMESCO Finland
Total colectomy and ileostomy
+∞
6.3
6
*
K83.2
ICD-10 Finland
Perforation of bile duct
+∞
6.3
6
*
6419
FHL
Other measure in this category
+∞
6.3
6
*
K50
ICD-10 Finland
Crohn disease [regional enteritis]
+∞
6.3
6
*
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
6.3
6
*
4AA33, ,
NOMESCO Finland
+∞
6.3
6
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
6.0
6.2
16
28
JN4BD
NOMESCO Finland
Extensive body CT
2.9
6.2
30
111
R94.5
ICD-10 Finland
Abnormal results of liver function studies
7.9
6.2
13
17
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
192
25
209.11
307.65
2.9
1.0
—
—
—
0
0
265
156
131.49
307.65
9.0
4.6
2.46
9.51
ug/l
1.49
208
125
202
12
506.35
307.65
2.7
1.0
—
—
—
0
0
195
43
126.17
307.65
3.2
1.3
0.89
0.59
g/l
1.54
183
33
240
61
187.77
307.65
8.4
2.9
30.42
2347.77
u/ml
0.50
225
51
182
63
71.19
295.21
2.8
1.1
4.29
—
iu/ml
—
11
0
136
13
189.51
276.24
1.9
1.4
11.28
10.23
umol/l
0.42
136
13
144
23
118.76
274.42
1.9
1.1
196.67
—
titre
—
9
0
228
183
47.77
265.39
4.5
2.4
13.03
9.67
g/l
20.23
222
169
193
261
18.72
154.83
11.6
2.1
8.02
8.97
umol/l
0.20
187
229
286
840
46.39
119.86
19.1
8.4
1.05
1.13
inr
2.04
101
258
221
536
12.64
104.86
3.7
1.4
2.62
2.21
g/l
3.47
214
343
141
232
10.52
91.56
2.9
2.4
21.90
24.71
%
1.17
130
207
97
107
12.88
84.78
2.1
1.4
—
—
—
0
0
68
45
19.21
80.21
7.3
5.5
962.00
821.17
iu/ml
—
16
6
45
13
40.50
72.30
1.1
1.1
—
—
—
0
0
274
1179
15.28
65.61
17.8
6.8
0.18
0.19
e9/l
0.60
264
1054
155
404
6.83
62.07
4.8
1.9
3.17
3.05
mg/l
0.19
144
348
269
1191
12.52
60.51
17.5
6.2
1.78
1.95
e9/l
1.96
261
1070
236
925
8.10
60.07
10.1
6.9
1.21
1.21
mmol/l
0.48
209
807
221
835
7.14
57.85
9.2
6.5
1.22
1.22
mmol/l
0.01
215
771
44
23
22.22
57.32
1.4
1.4
—
—
—
0
0
40
18
25.46
55.31
4.7
2.3
89.35
94.06
%
0.22
40
18
192
661
6.23
55.12
5.8
2.2
76.48
55.75
u/l
1.18
185
619
273
1338
11.83
51.59
21.8
10.2
3.48
4.02
e9/l
6.28
268
1174
56
60
11.23
48.70
1.3
1.4
—
—
—
0
0
54
55
11.74
48.63
1.4
1.4
422.50
162.00
u/ml
2.11
26
29
54
68
9.45
41.45
1.7
1.4
0.01
0.09
iu/ml
—
18
10
69
120
7.16
40.05
1.4
1.4
—
—
—
0
0
46
53
10.06
37.66
1.3
1.6
120.00
103.17
u/ml
—
5
6
144
503
4.56
37.38
3.6
2.4
—
—
—
0
0
94
240
5.23
36.07
12.0
7.1
105.84
103.97
mmol/l
5.29
94
240
209
1007
4.49
33.89
4.3
2.6
—
—
—
0
0
76
185
5.15
30.45
3.2
2.9
—
—
—
0
0
92
284
4.22
27.03
3.6
3.1
30.45
29.44
s
0.88
92
279
58
127
5.41
26.02
4.9
3.5
1.22
1.23
mmol/l
0.64
53
116
73
194
4.64
26.02
2.5
4.7
211.11
231.08
u/l
0.91
73
189
136
620
3.17
21.15
3.6
2.8
307.00
58.83
e6/l
0.40
108
476
31
17
20.16
20.90
3.7
1.4
0.84
1.08
g/l
1.12
31
17
126
556
3.17
20.63
3.7
2.7
0.31
0.36
e6/l
0.20
101
415
89
325
3.46
19.83
2.6
2.5
2.06
2.35
e6/l
0.16
54
176
31
49
6.94
19.22
1.4
1.2
—
—
—
0
0
58
162
4.19
19.05
2.5
2.3
66.84
73.46
ml/min/173m2
0.29
19
59
30
22
15.00
18.20
1.1
1.6
—
—
—
0
0
22
7
33.73
17.28
1.1
1.0
—
—
—
0
0
35
71
5.44
16.86
1.8
2.1
1.28
1.39
g/l
0.30
30
65
16
0
+∞
16.82
4.7
0.0
—
—
—
0
0
140
722
2.75
16.41
3.7
2.8
—
—
—
0
0
36
77
5.17
16.35
3.1
4.2
213.81
167.97
%
2.65
36
77
84
342
3.02
15.19
2.8
2.4
0.61
0.96
e6/l
1.00
51
193
56
180
3.59
14.90
5.4
5.4
1.03
1.69
mmol/l
0.77
48
150
283
2197
5.58
14.61
47.1
13.6
13.71
14.35
%
5.05
283
2167
97
437
2.80
14.48
2.4
1.8
1.45
1.42
%
0.19
90
411
22
34
6.90
13.84
6.7
3.5
52.86
58.03
%
0.77
22
34
13
0
+∞
13.64
4.3
0.0
3.34
—
mg/l
—
13
0
287
2301
5.98
13.04
34.8
9.6
94.90
91.45
ml/min/173m2
1.71
265
1860
133
731
2.46
12.94
2.4
1.7
93.35
96.84
pmol/l
0.46
82
373
86
398
2.62
11.90
2.0
1.4
19.27
20.51
nmol/l
0.38
86
344
69
308
2.61
10.13
2.3
1.8
—
—
—
0
0
21
44
5.05
9.69
1.0
1.1
—
—
—
0
0
33
100
3.58
9.48
1.8
1.6
—
—
—
0
0
18
19
10.00
9.40
1.3
1.1
—
—
—
0
0
74
354
2.44
9.33
1.9
1.6
473.23
12698841.85
pmol/l
0.50
65
315
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
44
4.80
8.72
2.3
6.8
0.23
0.32
u/ml
—
10
26
105
606
2.12
8.35
1.5
1.3
1.22
1.27
u/ml
0.04
24
160
47
193
2.70
8.06
15.6
8.8
-0.16
1.09
mmol/l
2.16
39
155
20
34
6.22
7.83
7.1
3.1
3.61
4.18
e9/l
0.52
20
34
59
279
2.39
7.53
2.0
1.5
1332.61
1191.71
nmol/l
0.42
49
219
41
166
2.70
7.21
17.5
8.3
118.71
125.92
g/l
1.11
41
158
10
5
20.61
7.18
1.3
1.2
—
—
—
0
0
12
12
10.36
6.59
1.2
1.0
1287.17
1327.58
miu/ml
0.04
12
12
15
23
6.80
6.42
1.0
1.1
—
—
—
0
0
45
203
2.43
6.33
2.3
1.6
—
—
—
0
0
156
1114
1.83
6.18
3.5
3.2
0.00
0.00
estimate
0.50
47
213
16
39
4.28
6.17
2.3
4.5
30.93
27.47
mg/l
—
9
34
280
2448
2.97
6.15
6.6
3.9
4.62
4.74
mmol/l
1.48
275
2310
45
207
2.38
6.07
2.2
1.7
—
—
—
0
0
156
1126
1.80
5.86
3.5
3.2
0.00
0.02
estimate
0.50
48
192
154
1112
1.79
5.74
5.1
4.5
0.00
0.00
estimate
-0.00
47
203
5
0
+∞
5.22
1.4
0.0
1.84
—
mg/l
—
5
0
81
499
1.85
5.00
2.3
2.2
1.80
0.98
mg/l
1.07
68
370
11
16
7.09
4.99
2.3
1.4
31.18
33.75
pg
0.99
11
16
24
95
2.66
4.42
1.8
1.5
—
—
—
0
0
16
52
3.19
4.15
2.4
1.3
—
—
—
0
0
25
105
2.51
4.10
1.3
1.4
—
—
—
0
0
7
8
8.92
3.79
1.6
1.6
24.57
32.13
umol/l
—
7
8
13
36
3.73
3.54
3.8
2.9
14.32
16.60
%
—
6
22
13
37
3.62
3.44
1.6
1.8
—
—
—
0
0
17
65
2.71
3.36
5.2
6.2
1.35
1.50
%
0.41
17
57
8
15
5.45
3.21
1.3
1.2
—
—
—
0
0
7
11
6.48
3.20
1.7
2.1
206.86
130.73
%
—
7
11
230
2005
1.62
3.15
3.5
3.4
—
—
—
0
0
15
58
2.67
2.92
2.4
2.5
—
—
—
0
0
56
363
1.67
2.81
3.2
3.6
31.02
319.38
ng/l
1.93
41
244
100
747
1.51
2.74
3.4
3.1
24.05
32.01
ng/l
0.32
56
419
11
36
3.13
2.59
1.7
1.6
—
—
—
0
0
6
11
5.54
2.55
2.0
3.7
—
—
—
0
0
6
11
5.54
2.55
1.7
1.3
13.37
8.38
ug/l
—
6
11
6
11
5.54
2.55
1.7
1.7
—
—
—
0
0
79
570
1.52
2.52
3.8
3.4
0.00
0.01
estimate
0.50
47
199
112
873
1.45
2.43
3.5
3.1
—
—
—
0
0
9
28
3.28
2.32
1.6
1.6
—
—
—
0
0
10
239
0.40
2.27
4.5
5.5
—
—
—
0
0
11
41
2.75
2.23
1.5
1.3
—
—
—
0
0
11
41
2.75
2.23
1.5
1.3
—
—
—
0
0
8
24
3.39
2.19
1.5
1.5
—
—
—
0
0
12
50
2.46
2.05
1.5
1.4
—
—
—
0
0
19
99
1.98
1.95
1.8
2.5
—
—
—
0
0
16
78
2.11
1.94
1.1
1.1
—
—
—
0
0
20
107
1.93
1.91
1.3
1.4
266.33
254.45
miu/ml
—
10
52
16
79
2.08
1.89
1.1
1.1
—
—
—
0
0
8
29
2.81
1.80
1.9
1.6
—
—
—
0
0
60
441
1.45
1.73
2.3
3.3
951.17
606.06
ng/l
0.33
50
360
0
47
0.00
1.72
0.0
1.5
—
17.03
—
0
40
7
25
2.84
1.66
1.7
1.4
—
—
—
0
0
264
2476
1.53
1.65
5.5
4.1
2.70
2.89
mmol/l
3.78
258
2327
7
26
2.73
1.59
2.0
1.6
—
—
—
0
0
5
16
3.16
1.44
1.0
1.4
—
18.19
—
0
7
7
29
2.45
1.40
1.3
1.5
—
—
—
0
0
7
29
2.45
1.40
1.3
1.5
—
—
—
0
0
7
29
2.45
1.40
1.3
1.5
—
—
—
0
0
7
29
2.45
1.40
1.3
1.5
—
—
—
0
0
7
29
2.45
1.40
1.3
1.5
—
—
—
0
0
7
29
2.45
1.40
1.3
1.5
—
—
—
0
0
69
540
1.36
1.39
3.8
3.8
2.82
8.70
mg/mmol
2.00
46
353
252
2363
1.40
1.37
4.9
3.5
1.18
1.31
mmol/l
2.67
247
2214
38
524
0.69
1.37
3.2
3.5
22.40
22.41
%
0.00
11
187
5
17
2.97
1.36
2.2
3.4
631.40
710.65
u/ml
—
5
17
0
37
0.00
1.35
0.0
1.1
—
—
—
0
0
0
39
0.00
1.34
0.0
1.1
—
—
—
0
0
5
18
2.81
1.29
1.0
1.2
—
—
—
0
0
11
56
2.00
1.23
2.3
2.1
—
—
—
0
0
10
49
2.08
1.23
1.8
1.6
—
—
—
0
0
13
72
1.84
1.17
1.2
1.2
—
3.06
—
0
10
5
20
2.52
1.15
1.0
1.1
—
—
—
0
0
5
20
2.52
1.15
1.2
1.8
—
—
—
0
0
5
20
2.52
1.15
1.0
1.1
—
—
—
0
0
0
36
0.00
1.14
0.0
1.1
—
—
—
0
0
8
40
2.03
1.13
2.4
2.1
—
—
—
0
0
5
21
2.40
1.09
2.4
3.0
105.80
105.86
mmol/l
—
5
21
11
59
1.90
1.09
1.1
1.3
—
—
—
0
0
28
390
0.69
1.08
2.2
2.4
0.93
0.73
ug/l
0.23
14
197
42
542
0.74
1.03
1.9
2.1
—
—
—
0
0
9
47
1.94
1.03
1.2
1.6
0.71
0.87
nmol/l
—
9
40
10
53
1.92
1.02
1.8
1.6
—
—
—
0
0
9
48
1.90
1.01
1.2
1.1
—
—
—
0
0
38
494
0.74
0.98
1.8
2.0
—
—
—
0
0
7
37
1.91
0.94
1.0
1.1
—
—
—
0
0
13
206
0.61
0.92
2.3
2.0
—
—
—
0
0
193
1790
1.22
0.88
4.3
3.7
14.48
14.58
pmol/l
0.20
179
1660
13
80
1.65
0.86
2.2
2.1
—
—
—
0
0
10
57
1.78
0.84
1.1
1.2
—
1.04
—
0
5
12
75
1.62
0.76
2.1
1.9
—
—
—
0
0
16
108
1.51
0.75
1.4
1.5
5.44
7.76
u/l
0.69
11
93
5
24
2.10
0.75
1.8
1.5
—
—
—
0
0
5
24
2.10
0.75
1.8
1.5
—
—
—
0
0
5
25
2.02
0.73
1.2
2.3
—
—
—
0
0
7
39
1.81
0.73
1.6
1.6
—
—
—
0
0
7
40
1.77
0.71
1.6
1.7
—
—
—
0
0
7
40
1.77
0.71
1.6
1.7
—
—
—
0
0
9
144
0.61
0.71
1.0
1.0
—
—
—
0
0
5
26
1.94
0.71
1.2
1.2
—
—
—
0
0
5
26
1.94
0.71
1.2
1.2
—
—
—
0
0
5
27
1.87
0.68
1.2
1.1
—
—
—
0
0
5
27
1.87
0.68
1.2
1.1
—
—
—
0
0
5
27
1.87
0.68
1.2
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
2.7
—
—
—
0
0
228
2183
1.18
0.58
4.7
4.3
1.97
2.36
mu/l
0.32
216
2030
6
37
1.63
0.56
1.3
1.5
—
—
—
0
0
22
169
1.33
0.55
1.2
1.2
—
—
—
0
0
13
91
1.45
0.54
1.8
1.8
—
—
—
0
0
20
253
0.78
0.47
2.1
2.0
—
—
—
0
0
12
161
0.73
0.42
1.5
1.5
—
—
—
0
0
24
195
1.25
0.42
1.1
1.3
68.83
168.54
iu/ml
—
6
78
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
1.19
—
0
8
13
97
1.36
0.40
6.5
4.6
0.81
0.67
%
0.69
13
97
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
6
41
1.47
0.36
1.0
1.5
—
—
—
0
0
56
621
0.88
0.35
1.7
1.5
—
—
—
0
0
17
136
1.26
0.34
3.9
4.1
0.75
1.40
mmol/l
—
8
102
11
143
0.76
0.33
1.4
2.2
1.81
8.26
ug/l
2.55
11
133
46
411
1.14
0.31
1.2
1.3
20.25
25.21
iu/ml
0.26
16
127
7
100
0.69
0.31
1.6
1.5
—
—
—
0
0
5
39
1.29
0.23
1.2
1.5
—
—
—
0
0
7
91
0.76
0.23
1.4
1.5
—
—
—
0
0
7
92
0.76
0.23
1.4
1.5
—
—
—
0
0
7
92
0.76
0.23
1.4
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
24.41
—
0
11
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.17
0.21
1.4
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
6.06
—
0
14
211
2152
0.94
0.18
6.3
4.6
37.39
38.51
mmol/mol
0.86
204
2038
8
72
1.11
0.16
1.4
1.5
—
—
—
0
0
12
102
1.18
0.15
3.8
3.0
117.42
125.72
ng/l
0.06
12
89
43
402
1.08
0.14
1.3
1.3
8.57
8.01
u/ml
0.03
15
158
32
342
0.93
0.11
1.2
1.6
—
—
—
0
0
6
55
1.09
0.09
1.3
1.2
—
—
—
0
0
5
65
0.77
0.08
2.8
1.8
—
—
—
0
0
7
84
0.83
0.07
1.3
1.1
—
—
—
0
0
37
357
1.04
0.05
1.6
1.4
—
—
—
0
0
230
2299
1.00
0.00
3.8
3.7
5.83
5.76
mmol/l
0.25
224
2135
14
144
0.97
0.00
1.9
1.8
—
—
—
0
0
7
78
0.90
0.00
1.4
1.3
—
—
—
0
0
5
50
1.00
0.00
1.0
1.1
—
—
—
0
0
6
65
0.92
0.00
1.2
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
106.29
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_UC_STRICT_PSC and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_UC_STRICT_PSC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_UC_STRICT_PSC – Ulcerative colitis (strict) with PSC
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data