This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Reduction defects of lower limb
Q17_REDUCT_DEFECTS_LOWER_LIMB_WIDE
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
131 |
4. Check minimum number of eventsNone |
131 |
5. Include endpointsNone |
131 |
6. Filter based on genotype QC (FinnGen only) |
125 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF13
- Parent code in ICD-10
- Q6[5-9]|Q7
- Name in latin
- Defectus reductionales membri inferioris
Similar endpoints
↥List of similar endpoints to
Reduction defects of lower limb
based on the number of shared cases.
Similar with more cases:
- Congenital malformations and deformations of the musculoskeletal system
- Congenital malformations, deformations and chromosomal abnormalities
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 125 | 75 | 50 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | 35.65 | 41.96 | 26.18 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 131
- Matched controls
- 1310
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q72.88
ICD-10 Finland
Other reduction defects of lower himb(s)
+∞
62.6
55
*
Q72.9
ICD-10 Finland
Reduction defect of lower limb, unspecified
+∞
40.8
37
*
M21.7
ICD-10 Finland
Unequal limb length (acquired)
65.5
10.8
12
*
R5110, ,
SPAT
9.6
8.6
17
20
Z3231
NOMESCO Finland
Registered nurse
3.0
8.2
50
222
Q72.6
ICD-10 Finland
Longitudinal reduction defect of fibula
+∞
7.4
7
*
Q72.80
ICD-10 Finland
Congenital reduction deformity of toe (toes)
+∞
7.4
7
*
Q72.4
ICD-10 Finland
Longitudinal reduction defect of femur
+∞
7.4
7
*
Q72
ICD-10 Finland
Reduction defects of lower limb
+∞
7.4
7
*
Z3229
NOMESCO Finland
Other healthcare associate professional
4.3
6.8
19
50
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
24.0
6.8
9
*
N02AX02
ATC
tramadol; systemic, rectal
2.6
6.7
56
288
R5140, ,
SPAT
+∞
6.3
6
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.6
6.2
23
74
R52.2
ICD-10 Finland
Other chronic pain
7.3
6.2
14
21
L17
ICPC
Foot/toe symptom/complaint
2.6
6.2
50
251
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
205
2.54
5.44
1.8
2.3
1.44
0.85
mg/l
1.04
31
154
29
144
2.30
3.50
1.9
1.6
782.80
1067.43
nmol/l
1.74
23
113
32
170
2.17
3.28
1.7
1.6
450.12
460.34
pmol/l
0.08
26
145
17
67
2.77
3.28
1.5
1.5
—
—
—
0
0
53
349
1.87
2.95
2.8
1.9
96.74
96.35
pmol/l
0.03
29
166
61
427
1.80
2.75
3.6
2.4
70.67
73.04
nmol/l
0.46
53
382
56
382
1.81
2.75
4.6
4.9
36.89
36.40
g/l
0.27
45
366
76
576
1.76
2.55
6.3
4.3
6.59
6.45
mmol/l
0.21
70
524
10
33
3.19
2.41
1.5
5.4
3.59
3.63
g/l
—
10
33
35
215
1.86
2.36
1.7
1.4
17.32
21.56
nmol/l
1.55
27
184
66
494
1.68
2.22
3.6
2.4
—
—
—
0
0
36
228
1.80
2.19
2.5
3.3
488.35
960.93
ng/l
1.55
28
192
61
454
1.64
2.05
11.2
6.5
1.23
1.21
mmol/l
1.02
55
395
36
234
1.74
2.00
3.4
1.9
—
—
—
0
0
35
227
1.74
1.95
2.9
3.2
323.46
4357.73
umol/l
1.05
24
201
56
413
1.62
1.93
11.7
6.1
1.22
1.21
mmol/l
0.46
51
382
7
23
3.15
1.82
1.1
1.1
—
—
—
0
0
89
743
1.62
1.77
6.0
4.1
10.63
10.67
mm/h
0.01
84
685
76
613
1.57
1.74
7.8
9.9
3.86
4.01
e9/l
0.23
67
534
28
179
1.72
1.63
1.3
1.3
7.42
6.50
u/ml
—
9
71
10
44
2.38
1.59
1.8
1.9
—
—
—
0
0
0
43
0.00
1.55
0.0
1.5
—
—
—
0
0
43
314
1.55
1.48
1.7
3.4
2.31
2.35
mmol/l
0.80
33
280
6
22
2.81
1.45
1.3
1.5
—
—
—
0
0
28
185
1.65
1.45
1.3
1.3
11.40
23.77
iu/ml
—
5
52
20
121
1.77
1.41
3.2
2.4
2.31
2.39
g/l
0.25
20
115
116
1059
1.83
1.39
19.2
12.4
23.48
21.99
mg/l
0.21
93
807
6
23
2.68
1.38
1.3
1.6
—
—
—
0
0
5
17
3.01
1.37
1.2
1.8
—
—
—
0
0
5
17
3.01
1.37
1.2
1.8
—
—
—
0
0
24
156
1.66
1.32
2.2
2.7
2.41
2.45
mmol/l
1.13
12
136
6
24
2.57
1.32
1.5
1.4
—
—
—
0
0
18
108
1.77
1.30
2.7
2.6
0.61
0.78
ug/l
—
10
65
24
158
1.64
1.26
2.0
1.7
—
—
—
0
0
8
37
2.24
1.24
1.4
5.3
77.38
96.41
%
—
8
37
6
26
2.37
1.20
13.2
4.2
10.30
8.80
kpa
—
6
26
33
238
1.52
1.19
2.7
2.1
3.45
2.97
mg/l
0.60
28
210
25
170
1.58
1.16
4.4
3.4
110.25
146.71
ng/l
0.14
16
118
8
41
2.01
1.11
4.0
2.6
1.05
1.33
%
—
8
41
6
120
0.48
0.99
1.0
1.6
—
—
—
0
0
6
28
2.20
0.93
3.5
3.7
10.27
10.06
g/l
—
6
28
6
30
2.05
0.88
3.7
3.5
3.58
3.39
g/l
—
6
30
6
30
2.05
0.88
3.7
3.5
7.35
7.48
g/l
—
6
30
6
30
2.05
0.88
3.7
3.5
—
—
—
0
0
8
44
1.87
0.87
1.5
1.8
—
—
—
0
0
39
308
1.38
0.87
1.3
1.3
0.57
1.32
u/ml
—
9
78
89
800
1.35
0.83
4.8
4.0
14.72
14.65
pmol/l
0.09
80
728
8
47
1.75
0.82
1.4
1.2
—
—
—
0
0
8
48
1.71
0.80
1.4
1.9
—
—
—
0
0
6
34
1.80
0.77
2.3
2.4
61.18
46.81
%
—
6
34
33
410
0.74
0.75
5.9
3.4
—
—
—
0
0
19
135
1.48
0.74
3.2
2.4
12.75
14.17
umol/l
0.42
19
127
48
403
1.30
0.70
9.9
9.6
0.98
1.21
inr
6.62
16
129
12
78
1.59
0.68
11.5
4.7
1.54
2.19
mmol/l
0.26
12
57
93
854
1.31
0.67
3.4
3.6
—
—
—
0
0
7
44
1.62
0.66
18.3
5.7
24.43
24.51
mmol/l
—
7
44
5
29
1.75
0.64
3.8
3.6
2.44
2.93
g/l
—
5
29
8
49
1.67
0.63
39.3
4.7
26.10
24.44
mmol/l
—
8
49
15
105
1.48
0.63
2.0
1.5
—
—
—
0
0
5
30
1.69
0.62
1.2
1.6
—
—
—
0
0
15
106
1.47
0.61
1.7
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
20
151
1.38
0.58
4.8
3.7
17.15
21.82
%
—
8
68
31
253
1.30
0.55
4.0
3.6
12.73
9.76
mg/mmol
0.15
18
160
11
77
1.47
0.47
1.5
1.6
—
—
—
0
0
23
281
0.78
0.45
7.2
2.9
0.13
0.29
e6/l
0.55
16
216
6
95
0.61
0.44
2.3
3.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
92.50
—
0
16
103
980
1.24
0.41
4.9
3.9
5.99
5.79
mmol/l
0.48
97
892
0
18
0.00
0.40
0.0
1.0
—
4.26
—
0
7
5
35
1.45
0.39
2.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
119.89
—
0
19
8
113
0.69
0.39
2.9
2.1
—
—
—
0
0
15
116
1.33
0.39
6.7
6.3
—
—
—
0
0
9
68
1.35
0.38
1.4
1.6
—
—
—
0
0
9
68
1.35
0.38
1.4
1.6
—
—
—
0
0
9
68
1.35
0.38
1.4
1.6
—
—
—
0
0
104
994
1.22
0.37
14.2
10.9
92.94
91.17
ml/min/173m2
0.30
90
790
7
54
1.31
0.31
22.4
9.7
1.07
0.66
%
—
7
54
7
54
1.31
0.31
22.4
9.8
1.71
1.25
%
—
7
54
37
329
1.17
0.30
5.3
3.1
35.19
34.94
ng/l
0.00
25
205
27
236
1.18
0.27
2.1
2.2
—
—
—
0
0
14
170
0.80
0.27
4.1
2.5
0.04
0.81
e6/l
—
5
98
17
200
0.83
0.25
1.5
1.4
—
—
—
0
0
13
107
1.24
0.22
15.0
5.5
104.62
103.99
mmol/l
0.20
13
107
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
256.30
—
0
10
0
13
0.00
0.21
0.0
4.5
—
92.13
—
0
13
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
26
286
0.89
0.17
5.7
3.7
0.00
0.00
estimate
-0.00
16
106
9
81
1.12
0.15
1.0
1.0
—
—
—
0
0
28
257
1.11
0.15
2.4
2.4
—
—
—
0
0
12
104
1.17
0.13
2.4
1.8
421.00
370.14
nmol/l
0.55
12
97
5
45
1.12
0.10
1.4
1.4
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
6
55
1.10
0.09
2.2
1.5
—
—
—
0
0
32
303
1.07
0.09
1.8
1.6
—
—
—
0
0
100
983
1.07
0.08
3.6
3.4
1.36
1.26
mmol/l
0.49
90
909
36
345
1.06
0.07
5.4
3.2
—
—
—
0
0
17
158
1.09
0.06
13.9
3.9
0.78
0.81
mmol/l
0.84
17
148
54
526
1.05
0.05
6.8
4.7
0.00
0.00
estimate
-0.00
17
107
101
1022
0.95
0.05
4.2
3.8
1.40
1.45
mmol/l
0.59
94
947
13
138
0.94
0.02
2.3
2.1
—
—
—
0
0
103
1036
0.97
0.00
5.0
4.2
2.79
2.77
mmol/l
0.09
96
962
103
1029
1.00
0.00
4.2
3.9
4.55
4.64
mmol/l
0.41
95
957
16
157
1.02
0.00
3.9
2.6
2.66
3.19
e6/l
—
7
86
53
529
1.00
0.00
5.3
3.4
0.00
0.00
estimate
-0.00
16
109
13
125
1.04
0.00
1.5
1.6
—
—
—
0
0
54
536
1.01
0.00
5.3
3.4
0.00
0.00
estimate
-0.00
17
102
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
8
82
0.97
-0.00
1.1
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
54
0.92
-0.00
7.2
7.0
26.90
24.96
mmol/l
—
5
54
0
6
0.00
-0.00
0.0
1.0
—
8.92
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.9
—
56.71
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
2.4
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
13.80
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
79
1.01
-0.00
21.5
5.9
117.88
124.58
g/l
—
8
79
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_REDUCT_DEFECTS_LOWER_LIMB_WIDE – Reduction defects of lower limb
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).