This is a non-core endpoint: only basic statistics are computed.

Protrusioacetabuli

M13_PROTRUSIOACETABULI

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M24.7 Hospital discharge: ICD-9 — 7186 Cause of death: ICD-10 — M24.7 Cause of death: ICD-9 — 7186 2 out of 7 registries used, show all original rules.	12
4. Check minimum number of events None	12
5. Include endpoints None	12
6. Filter based on genotype QC (FinnGen only)	12

Control definitions (FinnGen only)

Control exclude: M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M24
Name in latin: Protrusio acetabuli

NAME	M13_PROTRUSIOACETABULI
CONTROL_EXCLUDE	M13_ARTHROPATHIES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M247
HD_ICD_9	7186
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M247
COD_ICD_9	7186
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Protrusioacetabuli based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	121	74	47
Only index persons	107	64	43
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	59.97	47.22
Only index persons	50.51	56.32	41.85

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	12	8	-
Unadjusted period prevalence (%)	0.00	0.00	-
Median age at first event (years)	53.17	53.76	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

8.86

3.04

1.4

1.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

9.67

2.65

1.0

1.4

—

(3044640) Blood type and Crossmatch panel - Blood

5.23

2.07

1.6

1.8

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

4.91

1.72

6.4

2.1

—

(3013512) EKG study

3.95

1.54

3.0

3.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

3.97

1.41

2.4

2.7

—

(3026008) Bacteria identified in Urine by Culture

2.69

0.85

6.2

3.0

—

(1761868) Lipid panel - Serum or Plasma

2.04

0.51

1.2

3.4

—

(40768804) Tissue Pathology biopsy report

2.06

0.47

2.7

2.2

—

(3003694) ABO and Rh group [Type] in Blood

1.66

0.29

1.2

1.5

—

(3001604) Monocytes [#/volume] in Blood

1.66

0.27

6.0

3.8

e9/l

0.5

0.6

—

(3006315) Basophils [#/volume] in Blood

1.66

0.27

6.0

3.8

e9/l

0.1

0.0

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.22

0.0

1.0

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

0.22

0.0

1.9

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.0

—

(3044889) 12 lead EKG panel

1.03

0.00

3.9

3.5

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

62.8

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

0.00

0.0

2.6

—

14.9

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.0

—

(3022621) pH of Urine by Test strip

0.00

0.0

4.0

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.0

1.1

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.00

0.0

1.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.8

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

1.14

0.00

15.5

7.2

e9/l

4.1

4.3

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.8

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.8

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.8

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.4

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.9

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.6

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.8

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.0

1.1

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.8

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.7

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.0

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.0

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.00

0.0

2.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_PROTRUSIOACETABULI and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_PROTRUSIOACETABULI.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: M13_PROTRUSIOACETABULI – Protrusioacetabuli

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Protrusioacetabuli

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints