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Aphakia

DOID EFO Endpoint Browser PheWeb

H7_APHAKIA

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H27.0
  • Hospital discharge: ICD-9 — 3793A
  • Hospital discharge: ICD-8 — 37872
  • Cause of death: ICD-10 — H27.0
  • Cause of death: ICD-9 — 3793A
  • Cause of death: ICD-8 — 37872

2 out of 7 registries used, show all original rules.

663

4. Check minimum number of events

None

663

5. Include endpoints

None

663

6. Filter based on genotype QC (FinnGen only)

634

Control definitions (FinnGen only)

Control exclude
H7_LENS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H27
Name in latin
Aphakia

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10286 5262 4814
Only index persons 5128 2468 2660
Unadjusted period prevalence (%)
Whole population 0.14 0.15 0.13
Only index persons 0.10 0.09 0.10
Median age at first event (years)
Whole population 63.75 67.32 59.82
Only index persons 53.87 59.58 48.57

-FinnGen-

Key figures

All Female Male
Number of individuals 634 239 395
Unadjusted period prevalence (%) 0.14 0.08 0.18
Median age at first event (years) 56.98 57.18 56.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
662
Matched controls
6614
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
58.9
307.7
205
50
H27.0
ICD-10 Finland
Aphakia
+∞
307.7
427
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
71.4
307.7
277
66
S01ED51
ATC
timolol, combinations; ophthalmic
23.4
278.7
227
144
H25.1
ICD-10 Finland
Senile nuclear cataract
37.9
275.0
179
64
WX140
NOMESCO Finland
Parabulbar anesthesy
42.1
230.0
143
43
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
+∞
209.8
190
*
S01ED01
ATC
timolol; ophthalmic
22.7
202.0
159
91
WX100
NOMESCO Finland
Conjunctival surface anesthesia
53.8
200.0
116
26
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
9.5
192.7
390
867
H33.0
ICD-10 Finland
Retinal detachment with retinal break
41.4
174.8
108
31
114
Kela drug reimbursment
Glaucoma
12.0
173.1
207
241
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
+∞
170.3
156
*
S01EC01
ATC
acetazolamide; systemic
35.1
145.7
94
31
S01EA05
ATC
brimonidine; ophthalmic
32.6
133.4
88
31
S01EE01
ATC
latanoprost; ophthalmic
12.2
118.8
130
130
CKD60
NOMESCO Finland
Anterior vitrectomy
542.6
97.0
94
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
8.6
92.2
132
186
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
1010.2
92.1
88
*
37402
ICD-8 Finland
Cataract, Senilis
+∞
91.8
86
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
122.9
89.6
95
9
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
33.2
84.6
55
18
H26.4
ICD-10 Finland
After-cataract
298.1
79.3
79
*
S01EA03
ATC
apraclonidine; ophthalmic
45.9
78.9
47
11
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
+∞
76.5
72
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
100.9
73.8
80
9
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.3
72.4
181
440
S01EC04
ATC
brinzolamide; ophthalmic
13.9
71.9
69
55
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
185.8
65.3
67
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
13.3
63.2
62
51
CJB10
NOMESCO Finland
Laser discission of secondary cataract
94.5
62.2
68
8
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
31.1
61.9
41
14
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
6.9
60.7
102
169
S01EX03, ,
ATC
13.1
59.8
59
49
3631
FHL
Setting up an artificial lens as the only procedure
+∞
59.2
56
*
H25.8
ICD-10 Finland
Other senile cataract
215.3
58.0
59
*
3661A
ICD-9 Finland
Cataract, Senile cataract
+∞
57.1
54
*
37401
ICD-8 Finland
Cataract, Praesenilis
+∞
57.1
54
*
XCH00
NOMESCO Finland
Eye pressure measurement
12.6
56.5
57
49
XCK00
NOMESCO Finland
Perimetry
8.6
55.4
75
97
37403
ICD-8 Finland
Cataract, Complicata
300.0
55.0
55
*
S01BC05
ATC
ketorolac; ophthalmic
15.5
54.9
49
34
S01BA07
ATC
fluorometholone; ophthalmic
19.1
53.7
43
24
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.5
53.7
324
1438
37404
ICD-8 Finland
Cataract, Secundaria
+∞
52.8
50
*
S01BC03
ATC
diclofenac; ophthalmic
16.0
51.5
45
30
H27.1
ICD-10 Finland
Dislocation of lens
+∞
48.5
46
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
16.9
47.2
40
25
S01BA04
ATC
prednisolone; ophthalmic
11.9
47.1
49
44
S01BA01
ATC
dexamethasone; ophthalmic
8.8
46.8
61
75
H40.0
ICD-10 Finland
Glaucoma suspect
6.1
46.7
87
159
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
7.6
44.8
67
97
XCK10
NOMESCO Finland
Photography of fundus of eye
5.2
42.2
96
210
TCG10
NOMESCO Finland
Removal of sutures from cornea
+∞
42.1
40
*
S01EE03
ATC
bimatoprost; ophthalmic
13.7
41.1
39
30
37405
ICD-8 Finland
Cataract, Traumatica
+∞
40.0
38
*
Z94.7
ICD-10 Finland
Corneal transplant status
410.4
39.5
39
*
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
15.3
39.3
35
24
S01EE05
ATC
tafluprost; ophthalmic
9.2
39.2
49
57
S01AX11
ATC
[U] ofloxacin
7.6
37.4
55
78
37520
ICD-8 Finland
Glaucoma, Secondary
195.4
36.1
37
*
Q12.0
ICD-10 Finland
Congenital cataract
354.2
34.2
34
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
97.8
34.1
37
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
97.8
34.1
37
*
H16.0
ICD-10 Finland
Corneal ulcer
6.3
32.6
57
97
ZXA05
NOMESCO Finland
Left side
3.0
31.8
181
739
S01FA01
ATC
atropine; ophthalmic
41.3
31.5
39
10
H18.1
ICD-10 Finland
Bullous keratopathy
327.3
31.1
31
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
37.5
30.9
39
11
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
315.9
30.0
30
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.2
29.6
52
89
3625
FHL
Extracapsular nuclear cataract removal
+∞
29.4
28
*
H26.2
ICD-10 Finland
Complicated cataract
304.4
29.0
29
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
156.7
28.9
30
*
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
11.2
28.8
31
29
WX002
NOMESCO Finland
Sedation and analgesia
3.1
28.5
141
529
CKD20
NOMESCO Finland
Removal of vitreous body substitute
104.5
27.9
30
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
6.5
27.9
47
77
Z3229
NOMESCO Finland
Other healthcare associate professional
3.9
27.7
90
258
S01EE04
ATC
travoprost; ophthalmic
10.4
27.5
31
31
H25.0
ICD-10 Finland
Senile incipient cataract
9.1
27.3
34
39
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
+∞
27.3
26
*
3642
FHL
Anterior vitrectomy
+∞
27.3
26
*
ZXA00
NOMESCO Finland
Right side
2.7
26.8
191
869
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
38.5
26.4
33
9
3643
FHL
Vitrectomy through pars Plana
+∞
26.2
25
*
74439
ICD-8 Finland
Congenital anomalies of eye, Cataracta NUD
+∞
26.2
25
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
26.2
25
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
10.8
25.5
28
27
WX142
NOMESCO Finland
Sub-tenon anesthesy
52.2
25.4
30
6
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
135.0
24.8
26
*
ZXA10
NOMESCO Finland
Bilateral
3.3
24.3
105
361
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
+∞
24.1
23
*
ZXD20
NOMESCO Finland
Day surgery
3.4
24.0
94
304
S01EB01
ATC
pilocarpine; ophthalmic
24.7
23.7
33
14
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
+∞
23.0
22
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
67.4
23.0
26
*
H54.4
ICD-10 Finland
Blindness, monocular
124.2
22.7
24
*
CJW99
NOMESCO Finland
Other operation on lens
+∞
22.0
21
*
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
227.0
21.7
22
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
44.9
21.5
26
6
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
79.4
20.8
23
*
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
113.5
20.7
22
*
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
26.5
20.6
28
11
S01EC03
ATC
dorzolamide; ophthalmic
15.9
19.9
32
21
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
19.9
19
*
3639
FHL
Other measure in this category
+∞
19.9
19
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
19.9
19
*
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
75.8
19.8
22
*
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
108.2
19.7
21
*
3745
FHL
Hard membrane girding, cerclage with coagulation
108.2
19.7
21
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
20.8
19.2
28
14
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.3
18.9
25
31
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
72.0
18.8
21
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
7.4
18.3
27
38
37601
ICD-8 Finland
Detachment of retina, Secundaria
+∞
17.8
17
*
CGF10
NOMESCO Finland
Suture of laceration of cornea
+∞
17.8
17
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
97.6
17.6
19
*
CKC70
NOMESCO Finland
Circular buckling of sclera
97.6
17.6
19
*
3619
FHL
Other operations in this group, such as corneal refractive surgery
184.6
17.6
18
*
H26.1
ICD-10 Finland
Traumatic cataract
184.6
17.6
18
*
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
184.6
17.6
18
*
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
+∞
16.7
16
*
37600
ICD-8 Finland
Detachment of retina, Primaria
174.1
16.6
17
*
H17.8
ICD-10 Finland
Other corneal scars and opacities
174.1
16.6
17
*
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
174.1
16.6
17
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
23.7
16.5
23
10
H57.1
ICD-10 Finland
Ocular pain
5.3
16.1
33
65
H50.1
ICD-10 Finland
Divergent concomitant strabismus
34.3
15.8
20
6
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
7.1
15.8
24
35
H04.10
ICD-10 Finland
Dry eye syndrome
3.2
15.7
67
227
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
+∞
15.7
15
*
CJE00
NOMESCO Finland
Phakoemulsification
+∞
15.7
15
*
3665A
ICD-9 Finland
Cataract, After-cataract
+∞
15.7
15
*
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
87.1
15.6
17
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.3
15.6
41
100
H17.1
ICD-10 Finland
Other central corneal opacity
58.0
14.8
17
*
37400
ICD-8 Finland
Cataract, Infantilis, juvenilis
+∞
14.6
14
*
H3603, E103,
ICD-10 Finland
81.9
14.6
16
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
81.9
14.6
16
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
81.9
14.6
16
*
H26.02
ICD-10 Finland
Presenil cataract
81.9
14.6
16
*
S01AD03
ATC
aciclovir; ophthalmic
5.0
14.6
32
67
S01FA04
ATC
cyclopentolate; ophthalmic
13.8
14.3
24
18
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
+∞
13.6
13
*
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
+∞
13.6
13
*
3660C
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA PRAESENILIS]
+∞
13.6
13
*
CJF20
NOMESCO Finland
Removal of artificial lens
+∞
13.6
13
*
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
+∞
13.6
13
*
S01AA01
ATC
chloramphenicol; ophthalmic
3.7
13.4
44
126
H40.9
ICD-10 Finland
Glaucoma, unspecified
10.0
13.3
26
27
S01ED02
ATC
betaxolol; ophthalmic
14.2
13.3
22
16
S01FA02
ATC
scopolamine; ophthalmic
15.4
13.2
21
14
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
29.0
13.0
17
6
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
4.0
12.9
37
96
XCW10
NOMESCO Finland
Assessment of vision
23.1
12.9
18
8
CKC30
NOMESCO Finland
Cryopexy of detached retina
51.0
12.9
15
*
CG2S4
NOMESCO Finland
Photography of cornea
51.0
12.9
15
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
12.7
219
1364
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
71.2
12.6
14
*
3621
FHL
In the aftermath of the dissection
+∞
12.5
12
*
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
+∞
12.5
12
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
12.3
75
309
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
9.5
12.1
24
26
H53.0
ICD-10 Finland
Amblyopia ex anopsia
21.7
12.0
17
8
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
11.8
84
372
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
30.6
11.7
15
5
CKC60
NOMESCO Finland
Local buckling of sclera using implant
30.6
11.7
15
5
A10AA01, ,
ATC
5.0
11.5
25
52
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
11.5
11
*
3624
FHL
Extracapsular soft cataract removal
+∞
11.5
11
*
H18.2
ICD-10 Finland
Other corneal oedema
+∞
11.5
11
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
121.9
11.5
12
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
15.4
11.4
18
12
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
11.3
223
1440
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
44.0
10.9
13
*
ZXE00
NOMESCO Finland
One hour or less
1.8
10.8
215
1389
H18.4
ICD-10 Finland
Corneal degeneration
60.9
10.6
12
*
36409
ICD-8 Finland
Iritis, Unspecified
60.9
10.6
12
*
87091
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Sequelae
60.9
10.6
12
*
CFD10
NOMESCO Finland
Repair of conjunctiva
60.9
10.6
12
*
3604
FHL
Penetration of the cornea
111.6
10.4
11
*
S05.2
ICD-10 Finland
Ocular laceration and rupture with prolapse or loss of intraocular tissue
+∞
10.4
10
*
37700
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia corporis vitrei
+∞
10.4
10
*
3627
FHL
Intracapsular cataract surgery
+∞
10.4
10
*
37409
ICD-8 Finland
Cataract, Unspecified
+∞
10.4
10
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
10.4
10
*
H18.6
ICD-10 Finland
Keratoconus
33.1
10.4
13
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
23.8
10.3
14
6
H40
ICD-10 Finland
Glaucoma
14.9
10.0
16
11
XCD10
NOMESCO Finland
Electrophysiological examination of eye
8.3
9.9
21
26
3503
FHL
Single muscle retroposition
55.8
9.7
11
*
H44.2
ICD-10 Finland
Degenerative myopia
55.8
9.7
11
*
A10AB01
ATC
insulin (human); parenteral
3.9
9.6
28
74
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
101.3
9.4
10
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
101.3
9.4
10
*
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
101.3
9.4
10
*
H33.5
ICD-10 Finland
Other retinal detachments
17.8
9.4
14
8
H33.4
ICD-10 Finland
Traction detachment of retina
30.5
9.4
12
*
Q87.4
ICD-10 Finland
Marfan syndrome
+∞
9.4
9
*
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
+∞
9.4
9
*
3623
FHL
Extracapsular cataract aspiration
+∞
9.4
9
*
3768
FHL
Eye examination under general anesthesia
+∞
9.4
9
*
Z3231
NOMESCO Finland
Registered nurse
1.8
9.4
164
1013
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
13.9
9.2
15
11
H16.9
ICD-10 Finland
Keratitis, unspecified
7.9
9.2
20
26
H25.9
ICD-10 Finland
Senile cataract, unspecified
18.9
9.0
13
7
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
4.6
8.9
21
47
H54.0
ICD-10 Finland
Blindness, binocular
50.6
8.7
10
*
87001
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Non complicata (sive NUD)
50.6
8.7
10
*
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
50.6
8.7
10
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
7.8
8.7
19
25
H53.1
ICD-10 Finland
Subjective visual disturbances
3.0
8.5
37
127
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
27.9
8.5
11
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
27.9
8.5
11
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
20.3
8.5
12
6
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
20.3
8.5
12
6
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
91.1
8.4
9
*
CA1ME
NOMESCO Finland
Ultrasound oculometry
91.1
8.4
9
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
8.4
336
2574
L84
ICD-10 Finland
Corns and callosities
4.1
8.4
23
58
CJF99
NOMESCO Finland
Other operation on artificial lens
+∞
8.3
8
*
3714A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Corneal degenerations
+∞
8.3
8
*
3719
FHL
Other measure in this category
+∞
8.3
8
*
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
+∞
8.3
8
*
3649
FHL
Other measure in this category
+∞
8.3
8
*
H17.0
ICD-10 Finland
Adherent leukoma
+∞
8.3
8
*
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
8.3
8
*
3662A
ICD-9 Finland
Cataract, Traumatic cataract
+∞
8.3
8
*
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
8.3
8
*
37100
ICD-8 Finland
Corneal opacity, Cicatrix (nubecula, macula, leucoma) cornea
+∞
8.3
8
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.8
8.2
25
68
E9179
ICD-8 Finland
Striking against or struck accidentally by objects
4.6
8.2
19
42
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
11.9
8.1
14
12
CHC05
NOMESCO Finland
Iridotomy
11.9
8.1
14
12
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
6.4
8.1
20
32
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.9
8.0
115
665
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.8
8.0
24
65
H18.8
ICD-10 Finland
Other specified disorders of cornea
13.2
7.9
13
10
H02AB06
ATC
prednisolone; systemic
1.6
7.9
264
1930
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
45.5
7.7
9
*
A10AC01
ATC
insulin (human); parenteral
2.3
7.6
59
272
3700A
ICD-9 Finland
Keratitis, Corneal ulcer
80.9
7.4
8
*
Z97.0
ICD-10 Finland
Presence of artificial eye
80.9
7.4
8
*
J01MA02
ATC
ciprofloxacin; systemic
1.6
7.4
235
1690
XCH05
NOMESCO Finland
Eye pressure longterm registration
11.0
7.3
13
12
3711
FHL
Cyclodiateria or cryocoagulation
+∞
7.3
7
*
T85.3
ICD-10 Finland
Mechanical complication of other ocular prosthetic devices, implants and grafts
+∞
7.3
7
*
CGF45
NOMESCO Finland
Suture of laceration of sclera
+∞
7.3
7
*
CJD30
NOMESCO Finland
Pars plana lensectomy
+∞
7.3
7
*
H26.00
ICD-10 Finland
Infantile, juvenile and presenile cataract
+∞
7.3
7
*
3660B
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA JUVENILIS]
+∞
7.3
7
*
3793B
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[DISLOCATIO LENTIS]
+∞
7.3
7
*
CHE30
NOMESCO Finland
Suture of iris
+∞
7.3
7
*
3660A
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA INFANTILIS]
+∞
7.3
7
*
3716A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Keratoconus
+∞
7.3
7
*
3852
FHL
Reoperation for another reason
+∞
7.3
7
*
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
15.9
7.2
11
7
H21.0
ICD-10 Finland
Hyphaema
30.3
7.2
9
*
H33.2
ICD-10 Finland
Serous retinal detachment
30.3
7.2
9
*
37898
ICD-8 Finland
Other diseases of eye, Disease of eyeball, ocular muscle and orbit NEC
20.3
7.1
10
5
H54.7
ICD-10 Finland
Unspecified visual loss
20.3
7.1
10
5
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
5.7
7.1
19
34
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
12.2
7.1
12
10
A10AE04
ATC
insulin glargine; parenteral
2.2
6.9
58
276
S01AA12
ATC
tobramycin; ophthalmic
11.1
6.8
12
11
CKC12
NOMESCO Finland
Photocoagulation of retina
3.7
6.8
21
58
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
40.4
6.8
8
*
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
40.4
6.8
8
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
16.9
6.8
10
6
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
12.4
6.6
11
9
EBA00
NOMESCO Finland
Extraction of tooth
1.6
6.6
167
1131
ZXD05
NOMESCO Finland
Urgent procedure
1.6
6.6
173
1182
A10AB05
ATC
insulin aspart; parenteral
2.5
6.6
42
177
XCD20
NOMESCO Finland
Photoangiography of eye
8.8
6.6
13
15
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
6.6
86
482
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
70.4
6.4
7
*
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.9
6.4
29
102
H31.4
ICD-10 Finland
Choroidal detachment
+∞
6.3
6
*
3606
FHL
Keratophakic corneal surgery
+∞
6.3
6
*
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
+∞
6.3
6
*
25001
ICD-8 Finland
Diabetes mellitus, Cataracta diabetica
+∞
6.3
6
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
+∞
6.3
6
*
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
+∞
6.3
6
*
3633
FHL
Cataract removal through pars Plana
+∞
6.3
6
*
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
6.3
6
*
3632
FHL
Artificial lens removal
+∞
6.3
6
*
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
+∞
6.3
6
*
CJF50
NOMESCO Finland
Removal and implantation of artificial lens in posterior chamber
+∞
6.3
6
*
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
+∞
6.3
6
*
37408
ICD-8 Finland
Cataract, Alia
+∞
6.3
6
*
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
+∞
6.3
6
*
E913A
ICD-9 Finland
Accidental mechanical suffocation
+∞
6.3
6
*
H44.5
ICD-10 Finland
Degenerated conditions of globe
26.9
6.2
8
*
R42
ICD-10 Finland
Dizziness and giddiness
1.7
6.2
129
828
C03CA01
ATC
furosemide; systemic
1.5
6.2
237
1765
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.0
6.1
67
353
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
6.1
189
1340
CD2S4
NOMESCO Finland
Photography of eye
12.7
6.1
10
8
127
Kela drug reimbursment
Transplant complication
6.8
6.1
14
21
A46
ICD-10 Finland
Erysipelas
1.8
6.0
90
526

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
270
1972
1.62
8.14
10.4
6.6
1.21
1.21
mmol/l
0.14
226
1676
315
2401
1.59
7.87
7.0
4.7
7.30
6.81
mmol/l
2.41
294
2245
141
882
1.76
7.57
3.2
2.6
7.46
4.74
e6/l
0.76
132
793
171
1159
1.64
6.75
6.1
3.9
7.40
7.40
ph
0.25
36
195
71
369
2.03
6.73
1.7
1.6
—
—
—
0
0
126
790
1.73
6.66
1.8
1.7
1071.52
1126.63
nmol/l
0.30
98
599
92
533
1.84
6.33
9.0
5.1
1.12
1.03
mmol/l
2.16
86
492
237
1757
1.54
6.32
5.7
4.6
34.56
35.06
g/l
0.60
217
1626
104
626
1.78
6.31
3.1
2.3
12.99
13.01
umol/l
0.01
93
577
348
2803
1.51
6.25
3.9
3.6
15.13
14.98
pmol/l
0.51
305
2531
171
1185
1.60
6.09
2.5
2.0
197.68
266.95
u/l
0.48
156
1104
22
68
3.31
6.04
5.4
3.8
1.98
2.56
mmol/l
0.57
11
42
168
1162
1.60
6.03
4.2
3.0
1081.95
277.59
mg/l
0.78
121
743
175
1224
1.58
5.98
4.3
2.9
6.46
7.75
mmol/l
4.52
150
1019
259
1977
1.51
5.94
6.7
5.5
0.21
0.20
e9/l
0.68
236
1735
237
1778
1.52
5.89
7.2
5.6
—
—
—
0
0
130
850
1.66
5.84
2.9
3.0
555.15
577.40
mosm/kgh2o
0.55
108
725
78
442
1.87
5.75
1.7
1.5
—
—
—
0
0
260
1997
1.50
5.74
16.3
16.1
1.28
1.35
inr
0.63
87
561
104
646
1.72
5.64
3.3
3.2
0.82
0.81
mmol/l
0.08
97
599
236
1783
1.50
5.62
9.0
5.9
1.20
1.21
mmol/l
0.50
214
1614
374
3106
1.47
5.46
8.4
7.1
84.49
80.10
u/l
0.50
345
2891
174
1239
1.55
5.44
4.8
3.6
18.56
8.60
mg/mmol
1.09
126
780
173
1232
1.55
5.40
3.1
2.5
100.45
120.98
u/l
0.10
163
1138
254
1965
1.47
5.31
6.2
5.4
1.87
1.90
e9/l
0.12
234
1738
147
1014
1.58
5.27
2.3
2.0
2.93
3.16
mg/l
0.59
126
846
88
533
1.75
5.21
3.2
2.4
21.17
23.28
%
0.92
72
460
325
2643
1.45
5.20
5.3
4.5
16.63
4365.30
e6/l
—
8
47
474
4146
1.50
5.17
22.4
17.0
139.42
139.68
mmol/l
1.36
465
4016
247
1915
1.46
5.05
6.2
5.3
0.64
0.60
e9/l
1.63
219
1653
414
3536
1.45
5.02
4.9
4.3
2.01
1.97
mu/l
0.27
366
3200
284
2265
1.44
4.98
9.8
8.6
4.56
4.19
e9/l
1.43
254
1967
247
1919
1.46
4.98
6.3
5.3
0.04
0.04
e9/l
0.88
219
1659
211
1590
1.48
4.98
4.0
3.6
45.11
69.34
ng/l
0.45
148
1134
474
4162
1.49
4.93
22.9
17.1
3.99
3.99
mmol/l
0.11
462
4027
91
568
1.70
4.84
3.2
2.3
2.20
2.30
g/l
0.91
83
524
78
470
1.75
4.71
2.2
1.6
—
—
—
0
0
334
2767
1.42
4.64
5.2
4.1
—
—
—
0
0
243
1909
1.43
4.52
4.5
3.6
0.00
0.00
estimate
0.50
54
386
164
1195
1.49
4.51
4.1
4.2
—
—
—
0
0
245
1928
1.43
4.51
4.5
3.6
0.00
0.00
estimate
-0.00
48
340
220
1700
1.44
4.47
10.8
8.8
0.00
0.00
e9/l
0.11
185
1381
453
3985
1.43
4.33
19.0
14.3
30.41
26.11
mg/l
0.81
387
3174
339
2845
1.39
4.22
5.0
3.7
14.52
13.02
mm/h
0.91
312
2612
54
302
1.86
4.18
4.6
3.7
1.23
1.22
mmol/l
0.16
48
257
22
86
2.61
4.08
5.5
3.5
7.41
7.42
ph
0.48
22
76
239
1903
1.40
4.02
5.8
4.9
0.00
0.00
estimate
-0.00
47
350
166
1238
1.45
4.02
3.4
3.1
—
—
—
0
0
76
478
1.66
3.94
2.9
2.1
1.86
1.81
%
0.11
70
438
190
1460
1.42
3.90
3.1
2.2
77.98
76.54
nmol/l
0.31
172
1293
18
65
2.82
3.87
6.1
2.8
—
—
—
0
0
18
65
2.82
3.87
3.3
2.2
16.84
16.50
%
—
7
36
49
273
1.86
3.85
3.7
2.5
—
—
—
0
0
176
1339
1.43
3.81
3.9
3.4
2.34
2.35
mmol/l
0.37
155
1171
335
2837
1.36
3.79
4.4
3.8
—
—
—
0
0
67
415
1.68
3.69
7.5
3.2
2.03
2.08
mmol/l
0.04
61
332
114
802
1.51
3.68
1.6
1.6
1.33
1.20
mg/l
0.19
87
624
141
1036
1.46
3.66
5.6
3.9
0.00
0.01
estimate
0.50
43
331
59
354
1.73
3.64
2.7
2.3
5.50
7.39
ug/l
0.67
48
308
220
1751
1.38
3.64
6.2
5.4
0.64
0.65
%
0.09
205
1640
148
1099
1.44
3.64
4.0
3.3
—
—
—
0
0
42
228
1.90
3.58
1.5
1.5
—
—
—
0
0
417
3674
1.36
3.56
7.0
5.6
42.16
40.28
mmol/mol
2.82
378
3372
224
1798
1.37
3.49
6.2
5.4
2.83
2.88
%
0.12
208
1688
165
1259
1.41
3.48
4.5
3.4
175.86
68.40
e6/l
0.36
138
970
24
107
2.29
3.42
4.2
2.7
24.22
24.95
mmol/l
0.27
24
107
30
147
2.09
3.41
5.2
4.6
—
—
—
0
0
226
1823
1.36
3.40
6.3
5.5
59.41
57.73
%
1.18
209
1720
184
1436
1.39
3.39
5.0
3.8
116.64
149.28
e6/l
0.20
146
1027
230
1861
1.36
3.39
6.3
5.6
25.50
27.00
%
1.17
213
1754
207
1648
1.37
3.38
2.2
2.0
91.62
94.56
pmol/l
0.51
116
857
163
1248
1.40
3.36
3.2
3.1
1737.69
1574.53
ng/l
0.23
142
1074
194
1532
1.38
3.32
4.3
3.5
5.57
5.82
ph
0.69
15
101
19
77
2.51
3.31
3.8
2.3
—
—
—
0
0
13
43
3.06
3.26
2.8
1.2
—
—
—
0
0
255
2109
1.34
3.22
6.7
6.1
14.55
11.91
umol/l
0.91
244
2004
165
1276
1.39
3.20
3.4
3.3
31.54
32.64
u/l
0.25
157
1216
111
799
1.47
3.19
3.2
3.1
2.45
2.46
mmol/l
0.09
89
692
85
579
1.54
3.19
2.2
1.9
—
—
—
0
0
223
1811
1.35
3.17
6.4
5.7
8.81
8.81
%
0.00
207
1703
464
4191
1.35
3.16
12.4
9.9
26.95
26.50
u/l
0.13
446
4025
77
515
1.56
3.13
1.9
1.8
—
—
—
0
0
195
1554
1.36
3.13
3.3
2.6
181.41
150.91
ug/l
0.61
178
1415
149
1147
1.38
2.95
4.0
3.4
0.81
0.60
e6/l
0.29
122
871
120
894
1.42
2.87
4.5
3.7
—
—
—
0
0
136
1037
1.39
2.85
3.9
3.2
—
—
—
0
0
482
4409
1.34
2.82
27.9
21.1
243.24
242.83
e9/l
0.04
470
4261
482
4410
1.34
2.80
28.1
21.3
39.10
39.92
%
1.63
446
4082
482
4410
1.34
2.80
27.8
21.0
91.48
91.27
fl
0.46
476
4314
482
4411
1.34
2.79
27.9
21.1
7.15
6.78
e9/l
2.68
470
4243
482
4411
1.34
2.79
27.7
21.0
30.41
30.40
pg
0.03
476
4315
482
4411
1.34
2.79
27.9
21.1
4.38
4.48
e12/l
3.73
470
4248
482
4412
1.34
2.78
28.1
21.2
132.35
135.38
g/l
3.87
477
4313
55
355
1.60
2.63
13.6
8.6
—
—
—
0
0
20
94
2.16
2.56
2.3
1.5
—
—
—
0
0
7
190
0.36
2.44
1.6
1.4
—
—
—
0
0
111
841
1.38
2.41
5.2
4.0
1.02
1.02
kg/l
0.27
14
123
53
349
1.56
2.35
3.8
2.1
77.91
71.08
e9/l
0.49
42
272
6
13
4.64
2.27
6.0
6.8
—
—
—
0
0
214
1801
1.28
2.22
5.0
4.9
7.76
4.00
ug/l
0.32
186
1612
20
100
2.03
2.22
2.4
1.4
—
—
—
0
0
20
100
2.03
2.22
2.4
1.4
—
—
—
0
0
20
100
2.03
2.22
2.4
1.4
—
—
—
0
0
55
371
1.52
2.20
2.0
2.1
0.21
0.21
g/l
0.23
50
347
226
1918
1.27
2.19
2.7
2.5
—
—
—
0
0
63
439
1.48
2.17
1.5
1.3
393.33
387.50
titre
0.02
18
80
23
123
1.90
2.13
3.8
3.3
83.86
94.56
mg/l
0.07
18
104
23
123
1.90
2.13
3.8
3.3
40.56
37.31
mg/l
0.12
18
106
14
62
2.28
2.08
2.6
1.6
—
—
—
0
0
88
658
1.39
2.08
1.4
1.4
2.30
2.50
g/l
0.53
63
390
36
223
1.65
2.06
6.9
3.0
26.06
25.08
mmol/l
0.71
36
214
427
3918
1.25
2.02
5.6
4.8
2.55
2.70
mmol/l
2.78
387
3574
104
803
1.35
2.02
4.1
4.0
256.29
344.09
ng/l
0.35
89
661
419
3837
1.25
2.01
4.9
4.3
4.37
4.57
mmol/l
3.55
380
3521
9
32
2.83
2.00
1.0
1.1
—
—
—
0
0
132
1057
1.31
1.99
3.0
3.0
0.82
0.81
ug/l
0.04
96
713
445
4110
1.25
1.95
17.8
13.5
—
—
—
0
0
96
737
1.35
1.93
1.3
1.2
3.64
1.02
u/ml
0.40
33
179
108
845
1.33
1.92
1.8
1.7
107954938.55
417.86
pmol/l
0.49
88
704
65
468
1.43
1.91
2.1
2.4
12.19
9.23
umol/l
0.25
59
412
19
100
1.92
1.86
2.4
1.4
—
—
—
0
0
5
12
4.19
1.82
2.2
1.1
—
—
—
0
0
5
12
4.19
1.82
2.0
1.3
—
—
—
0
0
12
53
2.29
1.81
4.1
1.6
—
—
—
0
0
31
192
1.64
1.80
1.1
1.2
260.20
171.31
iu/ml
0.21
14
71
7
23
3.06
1.80
1.3
1.2
—
—
—
0
0
63
457
1.42
1.79
1.5
1.4
—
—
—
0
0
43
291
1.51
1.74
6.9
3.7
128.50
86.04
ng/l
0.96
38
249
8
30
2.68
1.72
1.3
1.2
—
—
nmol/l
—
0
0
5
13
3.86
1.71
2.4
3.2
—
—
—
0
0
30
187
1.63
1.71
4.3
4.8
1.65
1.52
%
0.40
30
173
0
46
0.00
1.71
0.0
1.6
—
—
—
0
0
17
89
1.93
1.71
2.9
2.0
131.00
131.79
g/l
0.04
12
66
66
488
1.39
1.69
8.8
7.8
0.56
1.12
mmol/l
0.37
56
385
12
55
2.20
1.68
1.7
1.2
—
—
—
0
0
412
3807
1.22
1.65
4.8
4.3
1.39
1.43
mmol/l
1.15
369
3480
44
303
1.48
1.65
5.4
3.5
—
—
—
0
0
10
41
2.46
1.65
2.4
3.4
—
—
—
0
0
39
264
1.51
1.59
4.0
3.5
7.40
7.41
ph
—
6
28
6
20
3.01
1.58
1.2
1.6
—
—
—
0
0
15
78
1.94
1.55
2.5
1.2
—
—
—
0
0
20
115
1.76
1.53
1.1
1.1
—
—
—
0
0
399
3693
1.20
1.50
4.3
3.9
1.27
1.29
mmol/l
0.30
354
3354
16
87
1.86
1.46
3.4
3.8
—
—
—
0
0
54
397
1.39
1.46
9.9
8.7
118.46
120.28
g/l
0.22
54
381
53
389
1.39
1.44
3.0
2.9
272.25
206.42
ng/l
0.67
48
360
12
59
2.05
1.44
4.7
2.9
—
—
—
0
0
5
16
3.14
1.44
7.0
3.8
—
—
—
0
0
28
181
1.57
1.42
3.9
4.9
0.92
0.87
%
0.40
28
169
9
40
2.26
1.40
1.1
1.2
—
—
—
0
0
126
1051
1.24
1.38
1.4
1.3
—
—
—
0
0
120
998
1.25
1.35
3.7
2.6
11003.27
11342.66
umol/l
0.02
101
862
40
283
1.44
1.34
4.4
3.8
0.36
0.17
%
0.42
14
94
9
42
2.16
1.34
1.1
2.6
—
—
—
0
0
412
3847
1.19
1.33
5.4
4.4
6.24
6.00
mmol/l
2.21
366
3466
19
305
0.61
1.31
1.2
1.4
—
—
—
0
0
9
44
2.06
1.27
1.4
1.4
—
—
—
0
0
42
305
1.40
1.24
4.4
3.7
0.94
0.88
%
0.07
16
116
37
263
1.43
1.23
4.6
3.9
0.00
1.35
%
0.60
11
75
50
375
1.36
1.22
1.5
1.6
—
—
—
0
0
35
250
1.42
1.14
1.5
1.5
—
—
—
0
0
175
1542
1.18
1.10
2.3
2.1
—
—
—
0
0
27
187
1.46
1.05
1.5
1.9
1.81
1.37
ug/l
0.11
22
161
115
980
1.21
1.05
8.1
6.8
—
—
—
0
0
44
333
1.34
1.04
4.6
3.5
—
—
—
0
0
109
928
1.21
1.00
1.8
1.6
19.21
20.17
nmol/l
0.34
95
781
38
283
1.36
1.00
2.0
3.0
—
—
—
0
0
270
2485
1.14
0.95
3.2
3.1
58.62
52.00
u/l
0.56
257
2307
36
269
1.36
0.94
4.0
3.7
0.93
0.64
%
0.31
14
95
6
27
2.23
0.93
1.2
1.3
—
—
—
0
0
9
52
1.74
0.92
1.4
1.6
—
—
—
0
0
28
201
1.41
0.92
3.6
3.7
—
—
—
0
0
64
520
1.25
0.92
1.2
1.2
—
—
—
0
0
28
202
1.40
0.90
2.9
2.4
0.55
0.63
%
0.76
28
202
6
29
2.08
0.89
2.3
2.6
—
—
—
0
0
6
29
2.08
0.89
1.2
1.2
—
—
—
0
0
36
274
1.33
0.85
5.5
4.7
—
—
—
0
0
80
673
1.21
0.85
3.9
3.2
2.30
2.20
e6/l
0.05
42
377
6
31
1.94
0.84
1.3
1.3
—
—
—
0
0
6
31
1.94
0.84
1.0
1.1
—
—
—
0
0
35
266
1.33
0.84
6.7
6.8
24.55
24.40
mmol/l
0.06
35
246
27
197
1.39
0.83
2.6
2.4
—
—
—
0
0
6
32
1.88
0.82
1.5
1.2
—
—
—
0
0
51
411
1.26
0.80
1.2
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
15
98
1.54
0.78
4.3
2.5
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
8.25
—
0
8
135
1200
1.16
0.77
4.7
3.9
—
—
—
0
0
5
24
2.09
0.74
3.6
2.0
—
—
—
0
0
148
1328
1.15
0.74
2.6
2.3
—
—
—
0
0
13
84
1.56
0.72
2.0
1.4
14731.50
21172.10
e6/l
—
8
59
5
26
1.93
0.70
2.2
2.5
13.54
13.10
%
—
5
26
7
41
1.71
0.70
1.1
1.3
—
—
—
0
0
46
559
0.81
0.68
1.3
1.2
14.91
12.23
u/ml
0.11
20
208
5
27
1.86
0.68
1.0
1.6
14.38
19.05
u/l
—
5
22
5
27
1.86
0.68
1.2
1.4
—
—
—
0
0
17
119
1.44
0.67
1.9
1.5
205.50
254.11
ug/g
0.52
12
68
10
62
1.62
0.65
3.8
2.8
4.07
4.46
e9/l
—
10
62
28
216
1.31
0.64
1.3
1.3
—
—
—
0
0
5
29
1.73
0.64
1.2
1.0
0.40
1.73
u/ml
—
5
17
6
104
0.57
0.62
1.3
1.2
—
—
—
0
0
10
63
1.59
0.62
4.1
3.1
58.20
59.11
%
—
10
63
5
30
1.67
0.61
4.2
2.8
—
—
—
0
0
8
50
1.61
0.61
1.8
1.5
—
—
—
0
0
18
131
1.38
0.59
2.7
4.6
—
—
—
0
0
14
97
1.45
0.59
1.1
1.1
—
—
—
0
0
14
97
1.45
0.59
2.9
1.5
—
—
—
0
0
32
256
1.26
0.57
3.0
2.6
3.82
8.29
e9/l
1.02
25
194
16
115
1.40
0.57
5.2
2.9
—
—
—
0
0
60
515
1.18
0.56
1.4
1.3
—
—
—
0
0
9
60
1.51
0.54
1.2
1.2
—
—
—
0
0
9
60
1.51
0.54
1.4
1.4
—
—
—
0
0
28
223
1.27
0.53
2.3
3.9
—
—
—
0
0
10
66
1.52
0.52
2.0
1.3
—
—
—
0
0
9
63
1.43
0.52
1.1
1.1
—
—
—
0
0
34
282
1.22
0.47
3.5
2.9
127.41
127.81
g/l
0.04
34
275
28
229
1.23
0.44
13.9
10.3
—
—
—
0
0
118
1278
0.91
0.42
3.8
2.8
—
—
—
0
0
16
122
1.32
0.42
9.9
9.0
—
—
—
0
0
5
32
1.57
0.42
2.8
2.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
60.70
—
0
10
0
16
0.00
0.41
0.0
1.8
—
4143.00
—
0
9
8
59
1.36
0.41
1.7
1.7
—
—
—
0
0
5
34
1.47
0.40
2.6
1.7
11.62
10.94
%
—
5
34
8
60
1.34
0.40
2.1
3.3
0.81
1.21
%
—
8
51
8
60
1.34
0.40
1.0
1.0
—
—
—
0
0
8
60
1.34
0.40
2.9
3.5
124.75
18.26
u/ml
—
8
60
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
1.43
—
0
11
5
36
1.39
0.38
2.0
3.6
63.20
57.52
%
—
5
31
11
147
0.74
0.38
1.0
1.1
—
—
—
0
0
46
403
1.15
0.37
2.0
1.9
271.02
136.46
ug/g
0.49
35
317
12
90
1.34
0.36
1.7
3.1
31.50
33.80
umol/l
0.12
12
83
19
153
1.25
0.35
1.1
1.3
—
—
—
0
0
7
55
1.27
0.30
1.4
1.4
—
—
—
0
0
8
106
0.75
0.29
1.0
1.1
—
—
—
0
0
108
1011
1.08
0.28
2.8
2.2
—
—
—
0
0
12
94
1.28
0.28
5.4
7.4
11.08
11.23
mmol/l
0.06
12
82
12
94
1.28
0.28
5.4
7.4
105.08
105.37
mmol/l
0.12
12
82
24
279
0.85
0.27
1.0
1.4
—
—
—
0
0
8
67
1.20
0.26
1.1
1.4
67.63
232.16
pmol/l
—
8
67
20
171
1.17
0.23
1.2
1.3
—
—
—
0
0
5
40
1.25
0.22
1.2
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
1.30
—
0
10
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
10
80
1.25
0.20
3.5
2.1
77.14
59.22
%
—
10
80
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
42
384
1.10
0.20
9.2
4.1
—
—
—
0
0
19
165
1.15
0.19
1.6
2.0
—
—
—
0
0
16
137
1.17
0.18
2.6
3.1
0.35
0.20
g/l
—
10
58
18
156
1.16
0.18
6.5
3.1
58.17
89.94
u/ml
0.28
18
149
10
121
0.82
0.18
1.8
1.8
—
—
—
0
0
7
61
1.15
0.17
1.9
1.3
—
—
—
0
0
6
77
0.78
0.15
1.2
1.4
—
—
—
0
0
39
361
1.08
0.15
1.4
1.4
—
—
—
0
0
9
81
1.11
0.15
1.7
1.2
—
—
—
0
0
8
98
0.81
0.13
3.1
1.7
—
—
—
0
0
26
238
1.10
0.13
1.7
1.7
—
—
—
0
0
12
104
1.16
0.12
2.0
2.7
—
—
—
0
0
5
48
1.04
0.09
2.6
2.5
—
—
—
0
0
6
55
1.09
0.09
1.8
2.9
—
—
—
0
0
11
123
0.89
0.08
1.5
1.8
53.55
38.36
nmol/l
0.91
11
118
10
88
1.14
0.08
1.4
1.3
—
—
—
0
0
7
67
1.04
0.08
1.4
2.7
—
—
—
0
0
7
68
1.03
0.08
1.4
2.6
4.11
4.16
mmol/l
—
7
68
7
68
1.03
0.08
1.4
2.6
105.43
105.25
mmol/l
—
7
68
103
1006
1.03
0.07
1.9
1.6
1.29
1.40
mmol/l
0.91
88
845
58
561
1.04
0.06
1.3
1.2
29.10
43.58
iu/ml
0.82
16
171
47
455
1.03
0.05
3.0
4.2
5.49
21.83
ug/l
0.86
40
390
25
261
0.96
0.04
1.2
1.2
—
—
—
0
0
20
190
1.05
0.03
2.1
3.3
—
—
—
0
0
12
112
1.07
0.02
1.7
1.6
—
—
—
0
0
10
106
0.94
0.01
1.3
1.2
—
—
—
0
0
36
357
1.01
0.00
2.4
2.2
10.86
12.75
nmol/l
0.77
30
315
34
335
1.01
0.00
1.8
1.4
—
—
—
0
0
11
105
1.05
0.00
2.6
1.8
11.41
12.43
mg/l
0.11
11
97
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
90.00
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
2.01
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
18.52
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.8
—
9321.75
—
0
8
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_APHAKIA and mortality.

Females

Parameter HR [95% CI] p-value
H7_APHAKIA 1.166 [1.01, 1.34] 0.033
Birth year 0.994 [0.99, 1.0] 0.218

During the follow-up period (1.1.1998 — 31.12.2019), 474 out of 1272 females with H7_APHAKIA died.

Males

Parameter HR [95% CI] p-value
H7_APHAKIA 1.201 [1.03, 1.4] 0.021
Birth year 0.985 [0.97, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 451 out of 1466 males with H7_APHAKIA died.

Mortality risk

Mortality risk for people of age

years, who have H7_APHAKIA.

N-year risk Females Males
1 0.09% 0.206%
5 0.591% 1.283%
10 1.564% 3.269%
15 2.999% 6.2%
20 5.598% 10.411%

Relationships between endpoints

↥

Index endpoint: H7_APHAKIA – Aphakia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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