Villonodular synovitis (pigmented)

M13_VILLONODULAR

pigmented villonodular synovitis: Pigmented villonodular synovitis (PVNS) is a rare benign proliferative disorder of the synovial membrane primarily affecting young adults (with a peak age of onset in the second to fourth decade of life) characterized by proliferative, locally invasive tumor-like lesions, usually involving a single joint, tendon sheath or bursae (most commonly the joints of the knee and hip and rarely others such as the ankle, shoulder and temporomandibular joints). It presents with pain and limitation of motion along with swelling, heat and tenderness over the involved joint, eventually leading to arthritic degeneration and significant locomotor deficit, if left untreated. PVNS can recur in patients even after treatment.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M12.2
  • Hospital discharge: ICD-9 7192
  • Cause of death: ICD-10 M12.2
  • Cause of death: ICD-9 7192

2 out of 7 registries used, show all original rules.

298

4. Check minimum number of events

None

298

5. Include endpoints

None

298

6. Filter based on genotype QC (FinnGen only)

298

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M12
Name in latin
Synovitis villonodularis [pigmentata]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2060 1083 962
Only index persons 1901 1014 887
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.04 0.04 0.03
Median age at first event (years)
Whole population 39.12 40.66 37.21
Only index persons 38.21 39.93 36.25

-FinnGen-

Key figures

All Female Male
Number of individuals 298 183 115
Unadjusted period prevalence (%) 0.06 0.06 0.05
Median age at first event (years) 40.29 40.74 39.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
276
Matched controls
2760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M12.2
ICD-10 Finland
Villonodular synovitis (pigmented)
+∞
169.9
145
*
7192F
ICD-9 Finland
Other and unspecified disorder of joint, Villonodular synovitis[SYNOVITIS VILLONODULARIS, POLVI]
+∞
128.4
113
*
1220
FHL
Arthroscopy
79.8
72.6
80
14
M17.1
ICD-10 Finland
Other primary gonarthrosis
34.8
70.2
92
39
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
28.6
57.4
79
38
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
88.8
46.8
51
7
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
65.2
46.5
53
10
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
55.2
42.7
50
11
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
57.7
41.3
48
10
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
461.5
41.3
40
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
19.0
41.0
64
43
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
448.0
40.2
39
*
A07EC01
ATC
sulfasalazine; oral, rectal
20.7
38.4
58
35
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
421.1
38.0
37
*
M13.9
ICD-10 Finland
Arthritis, unspecified
40.1
37.7
47
14
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
70.4
37.4
42
7
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
21.8
37.2
55
31
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
36.5
36.1
46
15
P01BA02
ATC
hydroxychloroquine; oral
26.7
34.0
47
21
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
186.6
32.5
33
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
350.6
31.5
31
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
350.6
31.5
31
*
WX320
NOMESCO Finland
Spinalanesthesy
6.5
31.5
94
204
1222
FHL
Arthroscopy and synovial surgery
337.4
30.4
30
*
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
36.4
30.0
38
12
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
29.7
28
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
60.0
27.8
32
6
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
19.8
27.2
41
24
M25.5
ICD-10 Finland
Pain in joint
5.0
27.1
103
291
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
285.9
26.2
26
*
L88
ICPC
Rheumatoid/seropositive arthritis
77.4
25.3
28
*
L15
ICPC
Knee symptom/complaint
5.4
21.6
72
170
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
11.3
21.5
41
42
NGF10
NOMESCO Finland
Total synovectomy of knee, open
+∞
21.1
20
*
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
10.3
21.0
42
47
9311
FHL
Knee cleansing surgery (synovectomy, debridement)
+∞
19.0
18
*
1221
FHL
Arthroscopy and meniscus surgery
107.4
18.8
20
*
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
47.6
18.5
22
5
M19.0
ICD-10 Finland
Primary arthrosis of other joints
18.6
17.8
27
16
1225
FHL
Arthroscopy and other therapeutic procedure
191.8
17.7
18
*
ZXA00
NOMESCO Finland
Right side
3.7
17.2
89
314
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
16.8
16
*
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
+∞
16.8
16
*
N02AX02
ATC
tramadol; systemic, rectal
2.9
15.3
126
615
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
7.3
15.3
37
57
M09AX01
ATC
hyaluronic acid; parenteral
26.8
14.9
20
8
L04AA13
ATC
leflunomide; oral
84.7
14.7
16
*
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
+∞
14.7
14
*
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
14.7
14
*
H02AB06
ATC
prednisolone; systemic
2.8
14.3
133
688
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
146.9
13.6
14
*
M01AX05
ATC
glucosamine; oral
4.4
13.5
51
134
M01AH05
ATC
etoricoxib; oral
2.6
13.2
172
1067
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
30.0
13.1
17
6
M23.8
ICD-10 Finland
Other internal derangements of knee
18.4
12.7
19
11
B01AB05
ATC
enoxaparin; parenteral
3.0
12.6
85
353
TNG10
NOMESCO Finland
Puncture of knee
+∞
12.6
12
*
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
+∞
12.6
12
*
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
135.9
12.5
13
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
7.6
12.5
29
42
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
11.7
134
758
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
26.3
11.3
15
6
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
11.3
111
577
ZXA05
NOMESCO Finland
Left side
2.9
10.9
75
314
WX111
NOMESCO Finland
Local infiltration anesthesia
114.2
10.5
11
*
M01CB01
ATC
sodium aurothiomalate; parenteral
114.2
10.5
11
*
M17.5
ICD-10 Finland
Other secondary gonarthrosis
+∞
10.5
10
*
M22.4
ICD-10 Finland
Chondromalacia patellae
34.0
10.4
13
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
5.6
10.4
30
59
M01AH02
ATC
rofecoxib; oral
3.8
10.2
45
136
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
6.0
10.0
27
49
J01AA02
ATC
doxycycline; systemic
2.5
9.9
219
1663
M01AH01
ATC
celecoxib; oral (coxibs)
3.1
9.9
58
216
A02BC02
ATC
pantoprazole; systemic
2.3
9.9
174
1180
SPAT1202
SPAT
Intra-articular injection
31.2
9.5
12
*
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
103.4
9.5
10
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
+∞
9.4
9
*
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
9.4
9
*
M01AE02
ATC
naproxen; oral, rectal
2.2
9.2
164
1103
B01AF01
ATC
rivaroxaban; oral
4.8
9.2
30
68
S18
ICPC
Laceration/cut
2.3
9.1
107
593
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
38.0
9.1
11
*
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
38.0
9.1
11
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
38.0
9.1
11
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
51.7
8.7
10
*
N03AX16
ATC
pregabalin; oral
2.7
8.7
65
282
N02BE01
ATC
paracetamol; systemic, rectal
2.5
8.6
231
1849
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
11.3
8.4
15
14
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
+∞
8.4
8
*
M01AE11
ATC
tiaprofenic acid; oral, rectal
7.9
8.3
18
24
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
34.5
8.1
10
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
4.8
7.8
25
56
M16.1
ICD-10 Finland
Other primary coxarthrosis
12.3
7.7
13
11
TQW40
NOMESCO Finland
Remowal of suture of skin
4.5
7.7
26
62
R4110
NOMESCO Finland
Physiotherapy
2.3
7.6
78
398
9243
FHL
Plastic of the patella and its tendons
82.2
7.5
8
*
M24.2
ICD-10 Finland
Disorder of ligament
82.2
7.5
8
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
8.7
7.4
15
18
N03AX12
ATC
gabapentin; oral
3.1
7.4
41
147
ZX140
NOMESCO Finland
Intra articular
+∞
7.3
7
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
+∞
7.3
7
*
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
+∞
7.3
7
*
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
30.9
7.2
9
*
M25.4
ICD-10 Finland
Effusion of joint
20.7
7.2
10
5
M01AC06
ATC
meloxicam; systemic, rectal
2.1
7.0
100
592
M02AA07
ATC
piroxicam; topical
2.1
6.9
95
553
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
11.3
6.9
12
11
L90
ICPC
Osteoarthrosis of knee
7.5
6.8
15
21
L04AA01
ATC
[U] ciclosporin; systemic
41.1
6.8
8
*
M01AX17
ATC
nimesulide; oral
2.4
6.7
63
307
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
8.1
6.7
14
18
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
6.5
60
291
M79.6
ICD-10 Finland
Pain in limb
2.1
6.5
92
541
L40.5
ICD-10 Finland
Arthropathic psoriasis
71.4
6.5
7
*
M19.2
ICD-10 Finland
Other secondary arthrosis
71.4
6.5
7
*
SPAT1153
SPAT
Removal of sutures
2.1
6.4
77
422
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
6.4
106
658
M20.1
ICD-10 Finland
Hallux valgus (acquired)
9.6
6.4
12
13
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
18.5
6.3
9
5
L04AA17
ATC
[U] adalimumab; parenteral
+∞
6.3
6
*
7190F
ICD-9 Finland
Other and unspecified disorder of joint, Effusion of joint[HYDROPS (HYDRARTHRON), POLVI]
+∞
6.3
6
*
7174A
ICD-9 Finland
Internal derangement of knee, Derangement of lateral meniscus
+∞
6.3
6
*
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
6.3
6
*
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
+∞
6.3
6
*
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
27.4
6.3
8
*
H02AB04
ATC
methylprednisolone; systemic
2.7
6.2
42
171
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.0
6.1
23
62
J01FF01
ATC
clindamycin; systemic
2.1
6.0
76
424

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3000475) Leukocytes [#/volume] in Synovial fluid
41
13
36.41
64.00
1.7
1.0
e6/l
18649.7
7562.3
—
30
8
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
37
15
28.02
53.12
1.5
1.0
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
22
11
21.51
28.68
1.7
1.0
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
32
6
59.47
27.78
1.4
1.2
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
79
288
3.37
17.47
1.3
1.1
u/ml
5.9
1.4
0.75
31
130
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
75
314
2.86
12.71
1.3
1.2
iu/ml
68.0
17.1
0.56
27
96
(3013707) Erythrocyte sedimentation rate by Westergren method
224
1615
2.56
11.27
5.7
3.1
mm/h
10.3
10.3
0.02
215
1479
(3006315) Basophils [#/volume] in Blood
166
1091
2.18
9.81
8.9
5.1
e9/l
0.0
0.0
0.24
147
941
(3013115) Eosinophils [#/volume] in Blood
169
1132
2.14
9.35
9.2
5.5
e9/l
0.2
0.2
1.01
150
997
(3001604) Monocytes [#/volume] in Blood
163
1088
2.10
8.97
9.0
5.1
e9/l
0.6
0.6
0.12
146
936
(3013650) Neutrophils [#/volume] in Blood by Automated count
186
1314
2.11
8.68
11.6
9.3
e9/l
3.7
4.1
1.34
166
1135
(3019198) Lymphocytes [#/volume] in Blood
165
1123
2.05
8.43
9.1
5.1
e9/l
1.9
2.0
0.29
146
988
(42870588) Differential panel, method unspecified - Blood
113
672
2.10
8.33
8.5
4.9
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
154
1028
2.03
8.25
9.4
5.1
%
2.6
2.9
0.72
148
965
(3044640) Blood type and Crossmatch panel - Blood
110
658
2.06
7.90
2.0
2.3
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
20
49
4.30
7.66
1.5
1.5
iu/ml
0.0
0.1
—
5
7
(3037522) Nuclear Ab [Titer] in Serum
51
236
2.40
6.81
1.5
1.3
titre
240.0
565.0
—
6
40
(3021879) Hepatitis B virus core Ab [Presence] in Serum
36
143
2.73
6.56
1.3
1.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
52
251
2.30
6.30
1.9
2.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
272
2351
2.80
6.29
14.8
11.7
mg/l
17.8
23.8
3.25
222
1746
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
218
1729
1.97
6.27
8.8
7.2
u/l
74.5
77.7
0.73
207
1627
(3019225) pH of Specimen
41
184
2.42
5.84
3.6
4.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
23
76
3.20
5.78
1.8
1.9
—
—
—
0
0
(3008898) HLA-B27 [Presence]
19
56
3.56
5.68
1.1
1.1
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
84
505
1.92
5.67
2.2
2.4
umol/l
339.3
10164.2
3.39
79
446
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
128
879
1.80
5.66
2.3
2.2
nmol/l
73.0
74.0
0.18
117
804
(3002256) Pathology report gross observation
55
289
2.11
5.38
1.2
1.2
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
10
18
5.71
5.36
2.0
1.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
188
1481
1.73
4.86
5.9
3.7
—
—
—
0
0
(40758558) Short blood count panel - Blood
85
539
1.81
4.76
8.2
6.7
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
131
948
1.68
4.55
3.7
4.1
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
44
229
2.08
4.40
19.3
15.2
inr
1.3
1.2
0.26
13
37
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
20
72
2.91
4.38
1.9
1.7
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
76
478
1.79
4.34
2.3
2.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
128
930
1.66
4.33
2.2
1.9
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
100
693
1.67
4.00
3.5
3.4
e6/l
10.7
138.9
2.05
70
482
(3011397) Hemoglobin [Presence] in Urine by Test strip
72
461
1.74
3.83
4.2
3.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
54
321
1.83
3.67
1.6
1.9
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
70
454
1.71
3.54
1.4
1.3
g/l
2.1
2.3
1.23
45
281
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
73
479
1.69
3.54
1.4
1.6
mg/l
1.4
1.1
0.20
51
359
(3017143) Hepatitis C virus Ab [Presence] in Serum
43
244
1.89
3.38
1.4
1.6
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
131
1006
1.54
3.27
5.3
7.8
mmol/l
1.2
1.2
0.01
118
862
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
12
38
3.25
3.25
1.1
1.1
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
99
716
1.57
3.22
2.7
3.7
mmol/l
2.4
2.4
0.07
92
641
(3019550) Sodium [Moles/volume] in Serum or Plasma
269
2458
1.97
3.09
14.3
13.5
mmol/l
139.9
139.7
0.68
263
2394
(3023103) Potassium [Moles/volume] in Serum or Plasma
269
2467
1.93
2.91
14.2
13.6
mmol/l
4.0
4.0
0.01
260
2400
(3028772) Osteocalcin [Mass/volume] in Serum or Plasma
6
9
6.77
2.88
5.8
3.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
244
2183
1.65
2.81
4.9
4.4
mu/l
1.9
2.4
0.52
233
2006
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
50
316
1.70
2.76
1.2
1.6
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
47
292
1.72
2.76
1.2
1.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
77
1044
0.65
2.75
2.1
2.7
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
7
14
5.09
2.74
1.1
1.1
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
256
2329
1.70
2.64
12.5
10.5
ml/min/173m2
85.4
84.6
0.24
211
1898
(3013512) EKG study
82
592
1.53
2.63
3.5
3.3
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
14
57
2.53
2.48
1.1
1.2
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
114
895
1.44
2.38
4.2
4.9
g/l
37.1
36.1
1.34
109
841
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
5
8
6.33
2.38
2.8
2.0
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
94
721
1.44
2.20
3.1
3.0
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
58
403
1.55
2.19
2.4
2.3
e6/l
4.5
5.0
0.11
53
353
(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method
6
14
4.35
2.16
1.0
2.3
—
14.5
—
0
5
(3000494) Fungus identified in Specimen by Culture
39
247
1.67
2.15
1.2
1.5
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
101
788
1.43
2.15
1.8
1.8
pmol/l
95.3
96.7
0.10
61
411
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
189
1643
1.41
2.14
2.8
3.1
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
114
910
1.41
2.13
4.6
6.6
mmol/l
1.2
1.2
0.04
106
846
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
279
2632
1.94
2.12
14.0
8.7
u/l
26.5
27.3
0.42
273
2553
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
5
10
5.06
2.08
1.0
1.0
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
131
1075
1.39
2.07
3.8
3.2
estimate
0.0
0.0
0.00
11
193
(46235355) HIV 1 and 2 tests - Meaningful Use set
57
400
1.53
2.06
1.5
1.8
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
73
543
1.46
1.99
5.4
4.8
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
24
135
1.85
1.98
4.8
2.5
e9/l
3.5
4.1
0.75
18
118
(3002582) Erythrocytes [#/volume] in Urine
79
598
1.44
1.96
2.9
2.9
e6/l
19.3
58.1
1.48
64
448
(3052851) Hemolysis interference index of Serum or Plasma
12
52
2.36
1.90
2.2
2.6
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
138
1162
1.35
1.78
6.0
6.9
umol/l
9.9
11.7
1.60
127
1113
(3030467) Casts [#/volume] in Urine by Automated count
71
537
1.42
1.76
3.0
2.8
e6/l
0.2
0.6
1.79
54
383
(3009261) Glucose [Presence] in Urine by Test strip
130
1087
1.35
1.75
3.9
3.2
estimate
0.0
0.0
0.50
11
189
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
13
62
2.15
1.68
1.5
1.7
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
16
83
1.98
1.68
1.1
1.3
miu/ml
179.8
222.3
—
9
38
(3021601) Nitrite [Presence] in Urine by Test strip
129
1084
1.34
1.66
5.3
4.4
estimate
0.0
0.0
—
10
193
(3007853) Bacteria identified in Skin by Aerobe culture
34
224
1.58
1.63
1.8
1.6
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
5
14
3.61
1.62
1.4
1.2
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
57
421
1.44
1.61
1.5
1.4
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
78
610
1.38
1.59
1.9
2.1
u/l
303.0
193.4
0.54
73
583
(3025468) Yersinia sp identified in Specimen by Organism specific culture
7
26
2.73
1.59
1.9
1.5
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
241
2233
1.41
1.56
5.1
5.0
mmol/mol
38.4
39.5
1.26
232
2094
(40768443) Skin Pathology biopsy report
16
86
1.91
1.53
1.4
1.1
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
7
27
2.63
1.52
1.9
1.5
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
7
27
2.63
1.52
1.9
1.5
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
7
27
2.63
1.52
1.9
1.5
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
7
27
2.63
1.52
1.9
1.5
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
7
27
2.63
1.52
1.9
1.5
—
—
—
0
0
(3003338) MCHC [Mass/volume]
233
2150
1.38
1.52
19.7
14.9
g/l
331.9
333.2
1.56
233
2137
(3023368) Bacteria identified in Blood by Culture
68
525
1.38
1.50
3.3
4.1
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
52
384
1.43
1.47
2.7
3.9
ng/l
36.6
409.2
1.39
37
274
(4035726)
29
189
1.59
1.47
1.3
1.4
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
5
16
3.16
1.44
2.8
3.6
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
45
327
1.44
1.39
3.0
2.6
e6/l
0.9
1.0
0.23
25
169
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
36
250
1.50
1.39
1.4
1.9
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
37
259
1.49
1.38
3.6
3.8
%
32.0
31.8
0.03
31
182
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
67
527
1.35
1.31
2.7
3.2
ng/l
610.3
1080.3
2.24
57
439
(3013826) Glucose [Moles/volume] in Serum or Plasma
144
1259
1.28
1.30
3.7
5.1
mmol/l
6.7
6.7
0.05
138
1173
(3048689) Calprotectin [Mass/mass] in Stool
39
280
1.45
1.29
2.1
2.2
ug/g
81.3
112.6
0.91
33
218
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
19
115
1.70
1.28
1.2
1.3
—
25.4
—
0
6
(3022621) pH of Urine by Test strip
20
123
1.67
1.27
2.1
2.3
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
10
49
2.08
1.23
1.4
1.2
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
266
2534
1.46
1.23
12.0
10.9
—
—
—
0
0
(44806118)
6
26
2.33
1.19
1.2
1.5
—
—
—
0
0
(44790047)
6
26
2.33
1.19
1.2
1.5
—
—
—
0
0
(44790049)
6
26
2.33
1.19
1.2
1.5
—
—
—
0
0
(44790048)
6
26
2.33
1.19
1.2
1.5
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
199
1824
1.27
1.17
4.4
3.8
pmol/l
14.5
14.6
0.25
191
1680
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
35
0.00
1.16
0.0
2.2
—
12.9
—
0
35
(3016244) Insulin [Units/volume] in Serum or Plasma
5
20
2.52
1.15
1.4
3.4
mu/l
41.0
12.0
—
5
20
(3047181) Lactate [Moles/volume] in Blood
12
65
1.88
1.15
3.8
14.3
mmol/l
1.8
1.3
0.50
12
57
(3017181) Myelocytes/100 leukocytes in Blood
26
176
1.52
1.15
3.9
5.1
%
2.0
1.3
0.36
12
54
(3024731) MCV [Entitic volume]
285
2761
1.74
1.14
22.8
16.9
fl
91.2
90.7
1.14
285
2721
(3035941) MCH [Entitic mass]
285
2762
1.73
1.12
22.7
16.9
pg
30.3
30.3
0.19
285
2721
(3026361) Erythrocytes [#/volume] in Blood
285
2762
1.73
1.12
22.9
16.9
e12/l
4.5
4.6
0.12
280
2690
(36304419) Bacteria [Presence] in Urine
66
531
1.31
1.11
3.0
2.8
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
7
31
2.29
1.11
1.3
1.6
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
285
2763
1.72
1.11
22.9
17.0
e9/l
6.7
6.6
0.38
278
2686
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
5
21
2.40
1.09
1.4
2.0
—
—
—
0
0
(3000963) Hemoglobin [Mass/volume] in Blood
285
2764
1.71
1.09
23.0
17.0
g/l
137.0
137.2
0.07
285
2721
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
39
290
1.40
1.08
1.4
2.0
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
27
187
1.49
1.08
1.1
1.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
242
2285
1.31
1.05
14.3
12.3
%
40.4
40.8
0.30
187
1756
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
9
46
1.99
1.04
1.9
1.5
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
61
490
1.31
1.04
4.4
3.2
kg/l
1.0
1.0
—
9
53
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
5
22
2.29
1.04
1.2
2.0
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
5
22
2.29
1.04
1.2
2.0
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
5
22
2.29
1.04
1.2
2.0
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
258
2460
1.36
1.03
4.4
4.0
mmol/l
4.8
4.8
0.06
246
2306
(3028707) Methadone [Presence] in Urine by Screen method
9
47
1.94
1.03
6.3
1.6
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
9
47
1.94
1.03
1.2
1.6
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
15
91
1.68
1.02
1.8
2.3
—
—
—
0
0
(3000492) Spirometry study
31
224
1.43
1.01
1.2
1.4
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
31
225
1.42
0.99
1.4
2.0
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
5
23
2.19
0.98
1.0
1.1
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
5
23
2.19
0.98
1.4
1.9
—
—
—
0
0
(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal
5
23
2.19
0.98
1.2
1.3
—
12.8
—
0
5
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
10
54
1.88
0.97
1.2
1.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
16
101
1.62
0.95
1.5
1.8
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
7
37
1.91
0.94
1.3
1.6
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
7
37
1.91
0.94
2.7
2.2
—
—
—
0
0
(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay
7
37
1.91
0.94
1.1
1.4
u/l
31.8
32.3
—
7
32
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
7
37
1.91
0.94
1.1
1.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
12
195
0.60
0.94
3.6
2.8
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
6
27
2.25
0.94
1.2
1.0
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
10
55
1.85
0.93
1.9
1.7
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
9
52
1.75
0.93
1.1
1.5
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
10
170
0.57
0.93
4.6
3.2
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
6
28
2.17
0.92
1.2
1.2
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
13
79
1.68
0.89
1.6
1.8
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
20
136
1.50
0.89
2.1
2.3
—
11.0
—
0
6
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
30
2.02
0.87
2.2
2.7
%
56.8
57.8
—
6
30
(3003327) Ova and parasites identified in Stool by Light microscopy
12
72
1.69
0.86
1.1
1.5
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
256
2453
1.31
0.86
4.3
4.0
mmol/l
1.4
1.5
1.57
243
2285
(3017446) Testosterone [Moles/volume] in Serum or Plasma
23
163
1.45
0.85
2.0
2.3
nmol/l
14.1
14.0
0.01
23
148
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
6
31
1.95
0.85
1.2
1.3
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
81
693
1.23
0.83
3.0
2.5
u/l
60.4
54.9
0.37
75
645
(3000330) Specific gravity of Urine by Test strip
15
97
1.58
0.83
3.3
3.7
—
—
—
0
0
(40761535) Cells panel - Urine sediment
23
164
1.44
0.82
4.8
3.4
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
18
123
1.49
0.79
1.6
2.9
mmol/l
2.4
1.4
1.12
12
95
(3021589) Normoblasts [#/volume] in Blood
114
1014
1.20
0.79
10.6
8.1
e9/l
0.0
0.0
0.64
88
817
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
25
0.00
0.79
0.0
1.9
—
32.3
—
0
25
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
28
0.00
0.76
0.0
1.6
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
13
83
1.59
0.76
1.2
1.4
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
17
116
1.49
0.76
1.5
3.2
—
—
—
0
0
(1002224) Polysomnography panel
17
116
1.49
0.76
1.1
1.1
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
7
39
1.81
0.73
1.7
6.1
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
11
68
1.64
0.72
6.3
1.9
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
21
152
1.41
0.71
1.1
1.2
u/ml
145.5
326.7
0.55
21
137
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
40
321
1.28
0.71
2.3
1.9
%
1.5
1.4
0.42
32
286
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
26
1.94
0.71
1.2
1.0
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
22
161
1.40
0.70
4.1
5.3
%
0.1
0.2
—
9
47
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
32
250
1.31
0.69
8.8
6.4
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
21
153
1.40
0.69
4.0
5.3
%
0.0
0.2
—
8
38
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
63
538
1.22
0.66
1.2
1.3
u/ml
0.6
2.0
1.06
13
146
(3009343) pH of Capillary blood
18
129
1.42
0.65
1.8
3.0
—
7.4
—
0
12
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
29
226
1.31
0.64
1.3
1.9
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
5
29
1.74
0.64
2.4
2.0
e9/l
5.4
4.6
—
5
29
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
5
29
1.74
0.64
1.6
1.6
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
17
121
1.43
0.64
1.1
1.1
—
104.2
—
0
5
(3027944) Amphetamines [Presence] in Urine
14
96
1.48
0.62
1.6
1.4
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
8
50
1.62
0.62
1.1
1.3
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
8
51
1.58
0.61
1.9
1.4
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
14
97
1.47
0.60
4.4
1.4
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
14
97
1.47
0.60
4.4
1.5
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
31
247
1.28
0.59
1.9
3.1
umol/l
3.6
8.9
2.19
25
217
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
60
516
1.20
0.59
3.7
3.6
%
22.0
21.5
0.06
25
220
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
30
238
1.29
0.59
1.1
1.3
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
14
195
0.70
0.58
1.2
1.7
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
14
98
1.45
0.57
4.4
1.4
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
6
36
1.68
0.57
1.8
2.1
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
11
73
1.53
0.57
1.2
1.5
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
258
2502
1.23
0.56
4.8
4.4
mmol/l
2.9
2.9
0.52
244
2336
(3032080) INR in Blood by Coagulation assay
90
806
1.17
0.56
5.7
7.1
inr
1.3
1.2
0.21
13
260
(3026782) Osmolality of Urine
47
398
1.21
0.55
2.2
2.5
mosm/kgh2o
552.8
547.4
0.06
40
335
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
9
61
1.49
0.54
1.3
1.2
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
180
1701
1.15
0.53
3.6
3.0
u/l
59.5
45.8
0.90
165
1610
(3022313) Gas panel - Capillary blood
14
100
1.42
0.53
1.5
2.5
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
9
63
1.44
0.53
1.0
1.2
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
244
2359
1.19
0.52
4.5
4.0
mmol/l
5.9
5.9
0.09
230
2189
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
244
2361
1.18
0.50
4.0
3.6
mmol/l
1.4
1.3
1.58
231
2201
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
12
166
0.71
0.49
5.0
3.2
mmol/l
1.2
1.2
0.39
12
146
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
38
319
1.22
0.49
3.0
2.7
e6/l
3.6
2.5
0.42
19
160
(3019309) Folate [Moles/volume] in Red Blood Cells
39
329
1.21
0.48
2.5
1.7
nmol/l
933.5
1258.2
1.65
27
243
(3020891) Body temperature
11
77
1.44
0.46
4.7
4.8
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
53
464
1.17
0.44
2.4
1.9
mg/l
3.0
3.0
0.00
47
400
(3029937) Albumin [Presence] in Urine by Test strip
52
591
0.85
0.44
5.3
3.3
estimate
0.0
0.0
0.50
11
193
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
11
151
0.72
0.44
2.2
1.6
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
69
620
1.15
0.42
3.3
4.0
mg/mmol
8.6
7.6
0.08
44
400
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
33
1.52
0.41
1.4
1.6
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
11
79
1.41
0.41
2.7
2.6
—
—
—
0
0
(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose
0
16
0.00
0.41
0.0
1.6
—
7.3
—
0
7
(3016879) Cocaine [Presence] in Urine
12
88
1.38
0.40
5.0
1.5
—
—
—
0
0
(3008152) Bicarbonate [Moles/volume] in Arterial blood
16
124
1.31
0.39
6.7
11.5
mmol/l
23.9
24.6
0.20
16
117
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
19
0.00
0.39
0.0
2.3
—
17.6
—
0
19
(3002179) Metamyelocytes/100 leukocytes in Blood
20
161
1.26
0.38
3.8
5.0
%
0.1
0.7
—
8
35
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
8
113
0.70
0.38
6.4
8.4
mmol/l
24.0
25.2
—
8
113
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
11
81
1.37
0.36
1.4
1.4
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
6
42
1.44
0.35
1.0
1.3
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
10
73
1.38
0.35
5.6
1.5
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
6
44
1.37
0.34
1.0
1.4
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
21
173
1.23
0.34
2.6
2.5
ug/l
3.2
8.7
2.30
21
153
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
43
380
1.15
0.33
2.6
2.5
ug/l
0.5
0.7
1.76
28
221
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
24
201
1.21
0.33
4.8
2.4
g/l
0.2
0.2
0.81
24
192
(3012516) Albumin [Mass/volume] in Urine
64
583
1.12
0.32
3.0
3.3
mg/l
57.2
516.2
1.31
44
373
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
6
47
1.28
0.32
1.0
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
6
47
1.28
0.32
1.0
1.3
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
17
138
1.25
0.31
1.1
1.0
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
17
138
1.25
0.31
1.2
1.3
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
7
53
1.33
0.31
1.3
1.2
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
7
57
1.23
0.29
4.4
4.6
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
9
117
0.76
0.28
1.8
2.1
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
8
64
1.26
0.27
1.8
1.7
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
69
641
1.10
0.25
3.5
3.1
mmol/l
7.9
7.9
0.02
62
551
(3007930) Methemoglobin/Hemoglobin.total in Blood
9
76
1.19
0.25
4.4
12.3
%
1.1
1.0
—
9
70
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
25
218
1.16
0.24
5.5
11.3
kpa
5.0
5.1
0.19
25
208
(3027801) Oxygen [Partial pressure] in Arterial blood
25
218
1.16
0.24
5.4
11.3
kpa
13.0
12.6
0.11
25
210
(3019060) Gas panel - Arterial blood
15
125
1.21
0.23
4.9
8.8
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
5
41
1.22
0.22
1.2
1.2
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
25
220
1.15
0.22
5.5
11.3
mmol/l
1.2
1.5
0.08
17
172
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
86
813
1.08
0.22
3.0
3.2
ng/l
19.9
87.1
0.81
55
521
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3034426) Prothrombin time (PT)
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3047189) Immunofixation for 24 hour Urine
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
0
11
0.00
0.21
0.0
1.8
—
59.0
—
0
11
(3048518) aPTT.lupus sensitive actual/normal (normalized LA screen)
0
10
0.00
0.21
0.0
1.3
—
1.1
—
0
5
(3044007) Cell count panel - Peritoneal fluid
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
41
448
0.90
0.21
1.9
1.7
pmol/l
474.8
29124154.5
0.76
36
388
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
(3018418) pH of Serum or Plasma
65
608
1.09
0.21
3.2
4.0
ph
7.4
7.4
—
7
122
(3015183) Erythrocyte sedimentation rate
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3028679) Herpes simplex virus Ab [Presence] in Serum
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
6
48
1.26
0.20
1.3
3.1
—
39.0
—
0
28
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
4.5
—
811.9
—
0
14
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
0
14
0.00
0.20
0.0
1.4
—
2.0
—
0
14
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
6
51
1.18
0.19
1.3
1.4
pmol/l
63.2
278.8
—
6
51
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
25
223
1.13
0.18
4.8
4.5
ug/l
2.7
8.4
1.76
17
195
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
19
166
1.15
0.18
1.5
3.1
ml/min/173m2
84.4
71.7
—
5
72
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
7
59
1.19
0.18
1.7
4.5
mg/l
25.4
29.8
—
7
53
(3034860) Kappa light chains.free [Mass/volume] in Serum
7
59
1.19
0.18
1.7
4.5
mg/l
26.8
46.1
—
7
54
(3026008) Bacteria identified in Urine by Culture
65
613
1.08
0.18
2.6
2.8
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
21
186
1.14
0.17
6.2
12.2
g/l
122.8
121.4
0.12
21
179
(40768793) Breast Pathology biopsy report
8
73
1.10
0.16
1.5
1.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
60
634
0.93
0.15
3.2
2.7
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
23
207
1.12
0.15
1.6
1.4
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
28
306
0.91
0.15
1.6
1.7
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
36
334
1.09
0.14
1.3
1.4
—
—
—
0
0
(3044889) 12 lead EKG panel
169
1654
1.05
0.13
3.4
3.3
—
—
—
0
0
(3022145) Colonoscopy Study observation
27
250
1.09
0.11
1.6
1.3
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
38
403
0.93
0.11
1.6
1.4
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
16
144
1.12
0.10
1.4
1.2
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
5
44
1.14
0.10
1.0
1.3
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
10
87
1.15
0.09
2.3
1.9
—
—
—
0
0
(3018572) Chloride [Moles/volume] in Blood
5
47
1.06
0.09
6.8
17.3
mmol/l
104.6
104.8
—
5
42
(3039000) Anion gap in Blood
5
47
1.06
0.09
6.8
17.3
mmol/l
10.2
11.7
—
5
42
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
6
54
1.11
0.09
1.2
1.3
—
3.4
—
0
9
(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis
7
65
1.08
0.08
1.0
1.4
g/l
0.0
1.5
—
7
60
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
6
70
0.85
0.07
1.5
2.1
%
101.0
86.7
—
6
62
(3020779) Urea [Moles/volume] in Serum or Plasma
19
176
1.08
0.07
1.5
8.5
mmol/l
6.3
8.3
1.91
19
170
(3048929) Epstein Barr virus Ab [Presence] in Serum
8
74
1.08
0.07
1.0
1.3
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
13
143
0.90
0.07
1.8
2.1
—
—
—
0
0
(4034850)
8
76
1.05
0.07
7.8
6.4
—
—
—
0
0
(3036489) Thrombin time
9
84
1.07
0.07
1.4
2.0
s
20.4
21.7
—
9
77
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
90
882
1.03
0.06
4.2
3.2
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
11
100
1.10
0.05
1.1
1.0
—
—
—
0
0
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
11
101
1.09
0.04
1.4
2.8
u/l
37.2
39.2
0.12
11
93
(4010399)
17
162
1.05
0.02
1.3
1.3
—
—
—
0
0
(3000991) Gas panel - Venous blood
16
168
0.95
0.02
5.0
9.4
—
—
—
0
0
(3012544) pH of Venous blood
20
193
1.04
0.01
1.8
3.7
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
20
193
1.04
0.01
6.4
12.0
%
95.4
96.0
0.22
20
187
(3004716) Salmonella sp identified in Stool by Organism specific culture
13
136
0.95
0.00
1.7
1.3
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
25
244
1.03
0.00
1.5
1.7
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
12
119
1.01
0.00
7.5
11.2
%
1.5
1.5
0.03
12
119
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
12
121
0.99
0.00
7.5
11.1
%
0.9
0.7
1.68
12
121
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
13
129
1.01
0.00
1.3
1.4
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
17
171
0.99
0.00
1.8
1.7
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
65
646
1.01
0.00
1.3
1.4
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
11
106
1.04
0.00
1.5
2.5
%
1.1
1.2
0.31
11
106
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
5
51
0.98
0.00
1.0
3.7
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
5
52
0.96
0.00
1.6
1.3
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
8
79
1.01
0.00
4.9
12.0
%
1.5
1.7
—
8
72
(40768446) Kidney Pathology biopsy report
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3009876) Amylase isoenzyme 3 panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
5
49
1.02
0.00
1.0
1.3
—
35.0
—
0
6
(3008536) Aspergillus sp Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
4.6
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
9
0.00
0.00
0.0
8.6
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
330.3
—
0
5
(3013293) Extractable nuclear Ab [Presence] in Serum
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
7
74
0.94
0.00
1.1
1.1
—
—
—
0
0
(3006109) Coagulation factor IX activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.2
—
98.6
—
0
5
(3035544) Cardiolipin IgG Ab [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3004451) EKG impression Narrative
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
5
54
0.92
0.00
3.6
3.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
10
100
1.00
0.00
7.9
17.4
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
11
110
1.00
0.00
1.5
1.7
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
7
73
0.96
0.00
1.1
1.1
—
—
—
0
0
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3023183) Ammonium ion [Moles/volume] in Plasma
5
49
1.02
0.00
2.0
4.2
umol/l
35.6
35.1
—
5
44
(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
73
0.96
0.00
1.1
1.1
—
—
—
0
0
(3013803) Aspergillus fumigatus IgG Ab [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
20.5
—
0
5
(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005685) Amylase.salivary [Enzymatic activity/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
58.8
—
0
5
(3006441) Cardiolipin IgM Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
28.0
—
0
7
(3000213) Normetanephrine [Moles/time] in 24 hour Urine
0
5
0.00
0.00
0.0
1.4
—
1.6
—
0
5
(3013005) Retinol [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
1.9
—
0
7
(3036035) von Willebrand factor (vWf) Ag actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
0.00
0.0
2.9
—
149.1
—
0
7
(3008116) Ketones [Moles/volume] in Urine by Test strip
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3048522) Glucose [Moles/volume] in Serum or Plasma --pre dose glucose
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033888) Pepsinogen I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
85.0
—
0
5
(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868415) European tick borne encephalitis virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3003985) Beta hydroxybutyrate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
4.2
—
0.7
—
0
5
(42868417) European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3032868) Hemoglobin electrophoresis panel in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(4094501)
6
63
0.95
0.00
1.2
1.0
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
9
92
0.98
0.00
3.0
1.7
ug/l
5.4
2.5
—
9
84
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4211845)
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_VILLONODULAR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_VILLONODULAR.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_VILLONODULAR – Villonodular synovitis (pigmented)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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