No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
231 |
4. Check minimum number of eventsNone |
231 |
5. Include endpointsNone |
231 |
6. Filter based on genotype QC (FinnGen only) |
221 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Deformity of finger(s)
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1492 | 854 | 627 |
| Only index persons | 1395 | 803 | 592 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 50.52 | 50.87 | 49.88 |
| Only index persons | 50.09 | 50.51 | 49.51 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 221 | 127 | 94 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | 52.23 | 50.27 | 54.88 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 231
- Matched controls
- 2310
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M20.00
ICD-10 Finland
Buttonhole deformity of fingers
+∞
137.7
118
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
48.8
83.3
50
13
M19.0
ICD-10 Finland
Primary arthrosis of other joints
36.4
64.9
42
14
M20.01
ICD-10 Finland
Swan neck deformity of fingers
+∞
61.2
56
*
M20.08
ICD-10 Finland
Deformity of finger(s)
+∞
54.3
50
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
14.4
42.2
41
34
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
12.4
35.8
38
36
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
13.1
31.6
32
28
A07EC01
ATC
sulfasalazine; oral, rectal
12.6
29.0
30
27
L04AX03
ATC
methotrexate; systemic
12.2
28.4
30
28
R4120
NOMESCO Finland
Occupational therapy
9.5
28.2
36
44
M25.5
ICD-10 Finland
Pain in joint
4.5
25.0
83
256
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
24.4
23
*
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
97.3
24.2
26
*
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
23.3
22
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
6.8
22.7
39
67
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
9.1
22.3
29
36
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
35.1
22.1
28
9
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
10.0
21.6
26
29
P01BA02
ATC
hydroxychloroquine; oral
21.9
20.1
29
15
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
217.9
19.9
20
*
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
+∞
19.0
18
*
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
19.0
18
*
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
19.0
18
*
S66.3
ICD-10 Finland
Injury of extensor muscle and tendon of other finger at wrist and hand level
19.0
16.0
24
14
M16.1
ICD-10 Finland
Other primary coxarthrosis
19.0
16.0
24
14
NDG76
NOMESCO Finland
Fusion of DIP joint
+∞
15.8
15
*
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
+∞
15.8
15
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
31.1
15.5
20
7
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
14.7
14
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
+∞
14.7
14
*
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
25.7
14.0
19
8
M20.2
ICD-10 Finland
Hallux rigidus
57.0
14.0
16
*
L88
ICPC
Rheumatoid/seropositive arthritis
36.5
13.7
17
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.0
12.8
29
64
M01AX05
ATC
glucosamine; oral
3.8
11.9
40
120
73799
ICD-8 Finland
Hallux valgus and varus
+∞
11.6
11
*
L04AA13
ATC
[U] leflunomide
126.0
11.5
12
*
L01BA01
ATC
methotrexate; systemic
45.6
11.0
13
*
H02AB06
ATC
prednisolone; systemic
2.5
10.8
116
659
X58
ICD-10 Finland
Exposure to other specified factors
3.4
10.8
45
155
N02AX02
ATC
tramadol; systemic, rectal
2.5
10.8
105
570
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
10.7
106
579
NDL99
NOMESCO Finland
Other operation on muscle or tendon of wrist or hand
63.0
10.7
12
*
M79.6
ICD-10 Finland
Pain in limb
2.5
10.5
101
544
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
+∞
10.5
10
*
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
+∞
10.5
10
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
+∞
10.5
10
*
WX320
NOMESCO Finland
Spinalanesthesy
3.0
10.4
55
218
M01AH05
ATC
etoricoxib; oral
2.5
10.4
144
915
TQW40
NOMESCO Finland
Remowal of suture of skin
4.6
10.4
26
62
N03AX12
ATC
[U] gabapentin; oral
3.2
10.2
46
166
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.8
9.9
33
98
NH3EA
NOMESCO Finland
Feet X-ray examination with load
57.5
9.7
11
*
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
4.6
9.6
24
57
NF1AA
NOMESCO Finland
Hip X-ray examination
5.5
9.5
19
37
L04AB04
ATC
adalimumab; parenteral
31.5
9.5
12
*
T92.3
ICD-10 Finland
Sequelae of dislocation, sprain and strain of upper limb
104.1
9.5
10
*
L15
ICPC
Knee symptom/complaint
2.9
9.4
52
211
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.6
9.3
70
332
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
5.1
9.3
20
42
X59
ICD-10 Finland
Exposure to unspecified factor
2.9
8.9
47
185
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
8.7
76
385
N03AX16
ATC
[U] pregabalin
2.7
8.7
58
259
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
17.1
8.7
13
8
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
28.7
8.6
11
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.6
8.6
62
288
NF1DA
NOMESCO Finland
X-ray of hips
93.3
8.5
9
*
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
93.3
8.5
9
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
3.0
8.4
42
160
L12
ICPC
Hand/finger symptom/complaint
2.9
8.4
46
185
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
+∞
8.4
8
*
7362A
ICD-9 Finland
Other acquired deformities of limbs, Other acquired deformities of finger[DEFORMATIO BOUTONNIôRE]
+∞
8.4
8
*
M70.6
ICD-10 Finland
Trochanteric bursitis
3.3
8.3
34
115
WX702
NOMESCO Finland
Supraglottic ventilation device
4.1
8.2
23
60
B01AB05
ATC
enoxaparin; parenteral
2.4
8.2
71
358
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.0
8.2
40
151
M54.5
ICD-10 Finland
Low back pain
2.3
8.1
87
481
ZXA05
NOMESCO Finland
Left side
2.5
8.1
61
288
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
8.0
111
681
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
7.8
95
551
T92.5
ICD-10 Finland
Sequelae of injury of muscle and tendon of upper limb
46.6
7.8
9
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
46.6
7.8
9
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
7.7
72
374
S18
ICPC
Laceration/cut
2.2
7.7
109
673
SPAT1153
SPAT
Removal of sutures
2.3
7.6
77
413
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
26.0
7.6
10
*
ZXA00
NOMESCO Finland
Right side
2.4
7.4
63
313
M01AH01
ATC
celecoxib; oral
2.9
7.4
39
153
NDL32
NOMESCO Finland
Suture or reinsertion of tendon of wrist or hand, extensor tendon
11.4
7.4
13
12
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
7.3
57
272
M19.2
ICD-10 Finland
Other secondary arthrosis
+∞
7.3
7
*
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
+∞
7.3
7
*
NDL66
NOMESCO Finland
Transposition of tendon of wrist or hand, other tendon
+∞
7.3
7
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
+∞
7.3
7
*
D07AD01
ATC
clobetasol; topical
2.7
7.3
44
186
N06AA09
ATC
amitriptyline; systemic
3.4
7.3
27
86
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
31.1
7.2
9
*
L04AX01
ATC
azathioprine; systemic
6.2
7.1
18
31
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.9
7.0
35
133
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
41.3
6.8
8
*
R29
ICPC
Respiratory symptom/complaint other
3.8
6.8
21
59
NDM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of wrist or hand
23.3
6.7
9
*
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
10.5
6.6
12
12
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
71.8
6.5
7
*
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
71.8
6.5
7
*
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
71.8
6.5
7
*
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
8.5
6.4
13
16
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
6.4
81
471
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
18.6
6.3
9
5
M07.3
ICD-10 Finland
Other psoriatic arthropathies
+∞
6.3
6
*
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
+∞
6.3
6
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
6.3
6
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
6.3
6
*
L04AB01
ATC
etanercept; parenteral
+∞
6.3
6
*
NDL62
NOMESCO Finland
Shortening of tendon of hand
+∞
6.3
6
*
NG1DA
NOMESCO Finland
X-ray of knees
+∞
6.3
6
*
S63.4
ICD-10 Finland
Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
13.0
6.1
10
8
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
7.0
6.1
14
21
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
7.0
6.1
14
21
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
9.0
6.1
12
14
J01CF02
ATC
cloxacillin; systemic
10.4
6.1
11
11
M01AX17
ATC
nimesulide; oral
2.3
6.1
54
272
M67.4
ICD-10 Finland
Ganglion
3.4
6.0
22
69
C05AA08
ATC
fluocortolone; rectal, topical
2.6
6.0
37
157
W22
ICD-10 Finland
Striking against or struck by other object(s)
3.5
6.0
21
64
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
75
391
2.36
8.00
2.3
2.4
331.58
11849.68
umol/l
3.16
67
348
48
210
2.62
7.40
1.4
1.1
26.45
1.52
u/ml
0.59
16
83
51
234
2.51
7.12
1.4
1.2
57.71
13.78
iu/ml
1.15
23
81
11
9
12.75
6.65
1.8
1.1
—
—
—
0
0
167
1285
2.08
5.82
7.2
3.2
12.70
11.06
mm/h
0.69
158
1167
114
788
1.88
5.26
2.7
2.4
—
—
—
0
0
138
1046
1.79
4.44
11.1
9.5
4.24
4.13
e9/l
0.25
132
894
61
360
1.94
4.43
1.8
1.5
1.57
0.98
mg/l
0.69
45
270
94
648
1.76
4.11
4.2
3.4
16.66
32.59
ng/l
1.68
62
447
173
1425
1.85
4.00
4.0
3.8
15.32
14.81
pmol/l
1.10
157
1292
73
472
1.80
3.94
2.6
3.2
897.76
1081.53
ng/l
0.20
59
410
207
1832
2.25
3.60
19.2
12.6
21.41
24.79
mg/l
0.74
178
1386
117
885
1.65
3.48
5.7
7.2
1.22
1.22
mmol/l
0.00
101
766
110
821
1.65
3.43
17.5
10.9
1.30
1.24
inr
0.22
27
250
81
563
1.68
3.30
2.8
2.3
57.56
66.91
u/l
0.41
75
521
107
800
1.63
3.27
5.2
6.0
1.22
1.21
mmol/l
0.08
98
730
38
215
1.92
3.08
1.7
1.7
1.58
1.46
%
0.27
33
192
167
1407
1.67
3.06
10.3
7.4
75.39
78.27
u/l
0.57
161
1318
100
760
1.56
2.73
5.2
4.8
35.76
35.63
g/l
0.09
91
706
113
885
1.54
2.68
5.4
3.2
0.00
0.00
estimate
-0.00
20
144
32
184
1.86
2.48
1.8
4.3
225.78
235.25
u/l
0.30
32
177
109
866
1.49
2.32
5.3
3.2
0.00
0.00
estimate
-0.00
22
161
7
18
3.98
2.27
1.1
1.1
—
—
—
0
0
119
969
1.47
2.20
6.0
6.7
9.37
11.38
umol/l
2.85
113
926
192
1730
1.65
2.15
5.2
4.5
1.89
2.61
mu/l
0.52
175
1574
52
358
1.58
2.12
1.6
1.7
261905152.26
444.35
pmol/l
0.49
42
301
127
1053
1.46
2.11
5.1
4.7
6.85
6.67
mmol/l
0.27
120
976
88
685
1.46
2.01
5.8
3.3
—
—
—
0
0
7
21
3.40
1.98
1.0
1.0
—
—
—
0
0
63
460
1.51
1.97
5.9
3.4
0.00
0.00
estimate
-0.00
19
149
216
2023
2.04
1.97
21.3
14.8
77.34
77.02
umol/l
0.05
216
2023
33
206
1.70
1.96
2.8
2.3
11.84
8.47
umol/l
0.25
27
180
108
877
1.43
1.96
7.1
4.4
0.00
0.00
estimate
-0.00
21
154
9
33
2.80
1.95
1.3
1.2
—
—
—
0
0
44
297
1.59
1.94
1.5
1.5
—
—
—
0
0
90
712
1.43
1.86
1.8
1.9
90.09
96.10
pmol/l
0.40
44
363
23
132
1.82
1.81
2.0
1.4
—
—
—
0
0
16
81
2.05
1.79
3.1
2.6
0.58
0.63
%
0.52
16
81
6
18
3.39
1.76
1.2
1.1
—
—
—
0
0
199
1833
1.62
1.76
4.2
3.8
1.25
1.28
mmol/l
0.23
183
1680
17
89
1.98
1.75
4.5
3.3
24.89
25.26
mmol/l
0.25
17
89
65
490
1.45
1.72
3.9
2.1
198.68
188.02
u/l
0.05
60
467
12
55
2.25
1.70
1.2
1.1
—
—
—
0
0
145
1260
1.41
1.70
3.7
2.8
49.23
44.38
u/l
0.45
133
1184
16
83
2.00
1.69
3.2
2.6
1.24
1.18
%
0.06
16
83
54
394
1.48
1.68
1.2
1.2
4.17
1.29
u/ml
0.35
14
113
55
404
1.47
1.66
2.5
2.2
—
—
—
0
0
44
309
1.52
1.64
3.6
2.5
1.78
1.17
e6/l
0.23
35
156
89
716
1.40
1.64
2.6
2.2
78.99
75.52
nmol/l
0.49
80
637
10
42
2.44
1.64
1.3
1.3
—
—
—
0
0
7
26
2.74
1.59
1.4
1.3
—
—
—
0
0
32
212
1.59
1.54
5.9
7.4
—
—
—
0
0
26
164
1.66
1.51
1.8
2.1
—
—
—
0
0
6
22
2.77
1.44
3.7
3.0
105.67
105.14
mmol/l
—
6
22
7
29
2.46
1.40
1.3
1.3
—
—
—
0
0
7
29
2.46
1.40
1.3
1.3
—
—
—
0
0
207
1954
1.57
1.28
5.5
4.7
2.76
2.79
mmol/l
0.22
191
1803
9
44
2.09
1.28
1.1
1.4
—
—
—
0
0
64
506
1.37
1.27
3.7
2.8
0.23
0.62
e6/l
0.97
56
359
8
37
2.20
1.22
1.1
1.6
—
—
—
0
0
10
50
2.05
1.18
1.3
1.3
—
—
—
0
0
11
58
1.94
1.14
2.5
1.6
—
—
—
0
0
7
30
2.37
1.13
1.0
1.1
—
—
—
0
0
201
1901
1.44
1.07
4.9
4.2
1.49
1.48
mmol/l
0.11
185
1751
91
781
1.27
0.99
3.2
2.5
149.70
129.69
ug/l
0.28
84
714
31
227
1.42
0.97
2.8
2.4
2.32
2.32
g/l
0.01
31
214
8
44
1.85
0.87
1.5
1.5
—
—
—
0
0
12
189
0.61
0.85
2.0
1.7
—
—
—
0
0
201
1917
1.37
0.85
5.1
4.2
4.72
4.70
mmol/l
0.07
187
1779
213
2053
1.48
0.83
14.3
9.0
26.36
25.64
u/l
0.29
207
1973
59
491
1.27
0.81
1.8
1.6
1.35
1.39
mmol/l
0.13
50
406
128
1162
1.23
0.80
3.1
3.0
—
—
—
0
0
15
99
1.55
0.77
2.1
3.2
0.14
1.32
mmol/l
—
10
82
5
24
2.11
0.75
1.0
1.1
—
—
—
0
0
25
186
1.39
0.74
1.9
2.2
—
—
—
0
0
7
39
1.82
0.73
1.6
1.5
—
—
—
0
0
7
40
1.77
0.72
1.1
1.1
—
—
—
0
0
7
41
1.73
0.70
2.9
1.6
0.00
0.00
g/l
—
7
41
75
654
1.22
0.68
4.5
2.9
—
—
—
0
0
27
209
1.33
0.64
5.4
8.0
0.44
1.40
mmol/l
0.91
20
168
8
49
1.65
0.62
1.6
1.4
—
—
—
0
0
219
2136
1.49
0.61
28.1
18.3
39.88
40.24
%
0.31
208
1985
21
157
1.37
0.61
4.0
3.1
—
—
—
0
0
8
51
1.59
0.61
2.6
4.6
32.94
25.92
mg/l
—
8
43
8
51
1.59
0.61
2.8
4.6
35.56
41.35
mg/l
—
8
42
8
51
1.59
0.61
2.6
4.6
—
3.52
—
0
7
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
190
1820
1.25
0.60
15.8
11.7
80.61
81.70
ml/min/173m2
0.28
166
1498
6
37
1.64
0.56
1.3
1.2
—
—
—
0
0
6
37
1.64
0.56
1.7
1.6
—
—
—
0
0
6
37
1.64
0.56
1.8
7.2
—
121.75
—
0
8
195
1878
1.25
0.55
5.0
4.2
5.77
5.94
mmol/l
1.60
177
1720
9
60
1.52
0.55
1.3
2.1
2012.67
257.63
ug/l
—
9
54
37
308
1.24
0.52
1.5
1.6
1039.75
1214.64
nmol/l
0.68
26
232
25
308
0.79
0.48
1.3
1.4
—
—
—
0
0
184
1769
1.20
0.48
6.3
5.3
39.05
39.84
mmol/mol
0.66
172
1638
5
84
0.59
0.46
1.2
1.6
1.90
4.32
mg/l
—
5
65
7
51
1.38
0.44
1.3
1.3
—
—
—
0
0
33
277
1.22
0.44
2.6
1.9
—
—
—
0
0
14
104
1.37
0.44
1.8
1.6
—
—
—
0
0
28
231
1.24
0.44
5.3
4.3
32.06
31.95
%
0.01
18
150
0
15
0.00
0.41
0.0
1.0
—
34.44
—
0
9
0
15
0.00
0.41
0.0
1.0
—
476.30
—
0
10
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
4.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
5
34
1.48
0.40
1.2
1.9
—
—
—
0
0
48
423
1.17
0.39
1.6
1.5
23.08
20.99
nmol/l
0.34
38
353
68
625
1.12
0.31
5.6
5.0
1.97
3.58
ug/l
1.46
59
562
24
203
1.20
0.31
2.8
1.8
—
—
—
0
0
13
102
1.29
0.30
1.4
1.3
—
—
—
0
0
27
233
1.18
0.29
5.6
5.2
1.04
1.01
mmol/l
0.22
22
216
14
113
1.25
0.27
1.6
1.6
—
—
—
0
0
18
212
0.84
0.25
2.2
4.5
4.33
23.48
ug/l
0.96
12
189
8
102
0.78
0.21
1.1
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
33
298
1.13
0.21
4.1
2.6
2.02
2.05
e6/l
0.01
24
146
0
13
0.00
0.21
0.0
1.5
—
8.44
—
0
13
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
23
204
1.14
0.19
3.0
1.8
—
—
—
0
0
11
92
1.21
0.16
1.5
1.3
—
—
—
0
0
58
548
1.08
0.16
3.9
3.8
4.02
7.83
mg/mmol
1.10
33
352
38
353
1.09
0.15
4.8
3.7
304.18
266.53
ng/l
0.05
28
273
54
511
1.07
0.14
5.6
4.5
23.03
21.76
%
0.23
30
253
16
142
1.14
0.13
4.9
3.3
70.10
65.73
ml/min/173m2
—
10
60
5
62
0.80
0.08
2.0
2.1
—
—
—
0
0
6
72
0.83
0.07
1.5
1.5
—
—
—
0
0
36
371
0.96
0.03
3.3
2.9
0.61
0.83
ug/l
1.49
22
243
63
618
1.03
0.03
1.9
4.0
2.33
2.36
mmol/l
0.93
53
544
10
97
1.03
0.00
1.6
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.2
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.3
1.9
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.5
—
—
—
0
0
5
57
0.87
-0.00
2.6
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
8.71
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_FINGERDEFORM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_FINGERDEFORM | 1.24 [0.96, 1.6] | 0.096 |
| Birth year | 0.999 [0.99, 1.01] | 0.752 |
During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 690 females with M13_FINGERDEFORM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_FINGERDEFORM | 1.117 [0.87, 1.43] | 0.381 |
| Birth year | 0.991 [0.98, 1.0] | 0.189 |
During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 494 males with M13_FINGERDEFORM died.
Mortality risk
Mortality risk for people of age
years, who have M13_FINGERDEFORM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.155% | 0.254% |
| 5 | 0.81% | 1.674% |
| 10 | 2.038% | 3.989% |
| 15 | 3.924% | 7.081% |
| 20 | 6.915% | 11.933% |
Relationships between endpoints
↥Index endpoint: M13_FINGERDEFORM – Deformity of finger(s)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data