No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
226 |
4. Check minimum number of eventsNone |
226 |
5. Include endpointsNone |
226 |
6. Filter based on genotype QC (FinnGen only) |
226 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to Deformity of finger(s) based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1492 | 854 | 627 |
Only index persons | 1395 | 803 | 592 |
Unadjusted period prevalence (%) | |||
Whole population | 0.02 | 0.02 | 0.02 |
Only index persons | 0.03 | 0.03 | 0.02 |
Median age at first event (years) | |||
Whole population | 50.52 | 50.87 | 49.88 |
Only index persons | 50.09 | 50.51 | 49.51 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 226 | 133 | 93 |
Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.04 |
Median age at first event (years) | 52.14 | 50.39 | 54.63 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 207
- Matched controls
- 2068
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint M13_FINGERDEFORM and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_FINGERDEFORM | 1.24 [0.96, 1.6] | 0.096 |
Birth year | 0.999 [0.99, 1.01] | 0.752 |
During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 690 females with M13_FINGERDEFORM died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_FINGERDEFORM | 1.117 [0.87, 1.43] | 0.381 |
Birth year | 0.991 [0.98, 1.0] | 0.189 |
During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 494 males with M13_FINGERDEFORM died.
Mortality risk
Mortality risk for people of age
years, who have M13_FINGERDEFORM.N-year risk | Females | Males |
---|---|---|
1 | 0.155% | 0.254% |
5 | 0.81% | 1.674% |
10 | 2.038% | 3.989% |
15 | 3.924% | 7.081% |
20 | 6.915% | 11.933% |
Relationships between endpoints
↥Index endpoint: M13_FINGERDEFORM – Deformity of finger(s)
GWS hits: -