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This is a non-core endpoint: only basic statistics are computed.

Hand

Z21_HAND

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 ZA4.0
  • Cause of death: ICD-10 ZA4.0

2 out of 7 registries used, show all original rules.

203

4. Check minimum number of events

None

203

5. Include endpoints

None

203

6. Filter based on genotype QC (FinnGen only)

196

Control definitions (FinnGen only)

Control exclude
Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z[AB]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 196 122 74
Unadjusted period prevalence (%) 0.04 0.04 0.03
Median age at first event (years) 55.15 53.89 57.21

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
203
Matched controls
2030
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZA4.0
ICD-10 Finland
Hand
4503599627370496.0
286.3
202
*
SPAT1104
SPAT
Monitoring of emergency patient
6.8
19.4
33
56
-31
ICPC
Medical examin/health eval partial
6.8
18.9
32
54
L12
ICPC
Hand/finger symptom/complaint
4.2
18.7
64
200
-48
ICPC
Clarification/discussion RFE/demand
18.8
16.6
25
15
G56.0
ICD-10 Finland
Carpal tunnel syndrome
4.0
14.9
50
152
L11
ICPC
Wrist symptom/complaint
4.7
14.5
37
91
ACC51
NOMESCO Finland
Release of median nerve
5.3
14.1
31
67
-60
ICPC
Result test/procedure
6.1
13.4
25
46
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
3.9
12.8
43
130
Z01.8
ICD-10 Finland
Other specified special examinations
3.2
12.2
65
264
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.1
11.6
36
102
-57
ICPC
Physical medicine/rehabilitation
115.7
10.5
11
*
WYA00
NOMESCO Finland
Screening and health check-up
14.3
9.9
16
12
SPAT1097
SPAT
Recording of ECG
3.2
9.2
41
148
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.2
9.2
41
148
X58
ICD-10 Finland
Exposure to other specified factors
3.1
9.1
43
160
SPAT1254
SPAT
Administration of medicine
3.3
8.8
37
128
Z20.9
ICD-10 Finland
Contact with and exposure to unspecified communicable disease
7.5
8.8
20
29
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.6
8.7
69
338
R04
ICPC
Breathing problem other
5.0
8.5
19
41
L15
ICPC
Knee symptom/complaint
2.6
8.5
62
291
Z25.1
ICD-10 Finland
Need for immunization against influenza
4.4
8.5
22
54
L81
ICPC
Injury musculoskeletal NOS
12.4
8.2
14
12
N02AX02
ATC
tramadol; systemic, rectal
2.3
8.0
99
590
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
4.7
7.9
19
44
-35
ICPC
Urine test
46.8
7.8
9
*
-34
ICPC
Blood test
9.4
7.7
15
17
-56
ICPC
Dressing/pressure/compress/tamponade
19.3
7.7
11
6
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
3.1
7.7
36
133
R4120, ,
SPAT
+∞
7.3
7
*
L86
ICPC
Back syndrome with radiating pain
4.2
7.2
20
52
L01
ICPC
Neck symptom/complaint
2.7
7.2
43
182
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
7.0
87
511
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
7.0
39
159
S04
ICPC
Lump/swelling localized
3.1
6.9
32
117
-54
ICPC
Repair/fix-suture/cast/prosth device
11.5
6.9
12
11
-50
ICPC
Medication/prescr/renewal
5.9
6.8
18
33
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.3
6.8
18
45
-43
ICPC
Other diagnostic procedure
23.4
6.7
9
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
7.3
6.7
15
22
-42
ICPC
Electrical tracing
14.9
6.5
10
7
Z29.8
ICD-10 Finland
Other specified prophylactic measures
6.3
6.5
16
27
R4110, ,
SPAT
3.2
6.4
27
93
R5110, ,
SPAT
4.2
6.3
17
43
SPAT1249
SPAT
Treatment-related counselling outside office
2.1
6.3
89
546
A03
ICPC
Fever
2.5
6.3
46
214
L14
ICPC
Leg/thigh symptom/complaint
3.6
6.2
21
63
N17
ICPC
Vertigo/dizziness
2.9
6.1
31
119

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21
46
4.98
9.30
3.0
3.6
0.59
0.12
g/l
—
5
17
20
55
3.92
6.66
4.3
2.0
—
—
—
0
0
194
1689
4.35
6.56
16.3
11.5
18.52
21.79
mg/l
0.84
169
1319
13
17
8.09
6.23
2.3
1.8
—
—
—
0
0
72
423
2.09
5.58
3.8
3.3
—
—
—
0
0
31
131
2.61
5.12
4.4
3.7
—
—
—
0
0
159
1267
2.18
5.01
4.5
3.9
15.00
14.51
pmol/l
1.63
154
1164
156
1237
2.13
4.94
7.3
6.8
69.50
76.17
u/l
2.55
151
1156
104
729
1.87
4.63
9.9
6.7
1.22
1.22
mmol/l
0.22
95
628
84
550
1.90
4.62
3.7
3.2
32.45
34.57
ng/l
0.06
58
337
44
229
2.18
4.57
2.4
2.3
256.15
107.25
ug/g
0.67
34
179
29
128
2.48
4.38
1.2
1.1
—
—
—
0
0
27
116
2.53
4.31
3.3
2.1
—
—
—
0
0
113
829
1.82
4.21
4.8
5.7
9.60
10.69
umol/l
0.97
107
793
8
10
8.27
4.10
1.1
1.3
1.74
1.69
mmol/l
—
8
10
42
226
2.08
3.98
1.4
1.5
668.57
539.65
titre
—
7
57
177
1517
2.30
3.96
5.8
5.1
39.21
39.13
mmol/mol
0.04
172
1435
21
85
2.64
3.77
2.0
1.8
—
—
—
0
0
85
587
1.77
3.76
2.3
1.8
103.93
96.12
pmol/l
0.56
52
284
184
1615
2.49
3.69
4.7
4.1
5.83
5.84
mmol/l
0.06
178
1501
38
203
2.07
3.66
2.7
2.1
—
—
—
0
0
7
9
8.00
3.58
2.3
1.0
—
—
—
0
0
41
229
1.99
3.50
3.0
2.6
5.67
2.61
e6/l
1.04
30
124
120
929
1.71
3.43
4.4
4.6
6.36
6.53
mmol/l
0.39
113
853
58
366
1.82
3.43
3.4
3.5
1.01
1.02
kg/l
0.33
19
51
72
485
1.75
3.41
2.9
2.1
—
—
—
0
0
49
298
1.85
3.24
1.2
1.3
18.60
10.17
u/ml
0.21
18
119
145
1200
1.73
3.08
3.2
3.0
35.81
43.41
u/l
1.24
139
1144
185
1656
2.32
3.04
4.8
4.1
1.46
1.49
mmol/l
0.43
176
1558
57
370
1.75
3.03
1.2
1.2
0.49
1.82
u/ml
1.60
15
108
9
21
4.43
3.03
1.2
2.0
—
—
—
0
0
180
1597
2.12
2.98
4.6
3.7
1.27
1.26
mmol/l
0.05
172
1495
185
1660
2.29
2.95
4.9
4.2
4.68
4.74
mmol/l
0.28
179
1570
56
365
1.74
2.93
3.7
3.7
—
—
—
0
0
9
23
4.04
2.81
2.8
2.4
—
—
—
0
0
187
1692
2.33
2.80
5.1
4.5
2.81
2.82
mmol/l
0.04
181
1588
34
195
1.89
2.68
3.8
2.1
2.40
2.41
g/l
0.06
34
176
34
196
1.88
2.64
1.2
1.3
—
—
—
0
0
89
669
1.59
2.63
11.6
10.2
1.13
1.20
inr
0.36
28
198
25
130
2.05
2.59
5.9
4.1
0.64
0.87
%
0.17
14
42
23
116
2.11
2.58
4.5
4.1
0.65
0.44
%
0.25
13
32
6
11
5.58
2.56
1.0
1.1
—
—
—
0
0
193
1786
2.64
2.45
17.2
10.9
—
—
—
0
0
30
172
1.87
2.37
11.3
5.3
1.05
1.04
mmol/l
0.12
30
161
47
309
1.68
2.35
1.3
1.3
11.28
33.21
iu/ml
2.47
16
107
23
122
2.00
2.27
5.8
3.0
69.59
72.95
ng/l
0.07
23
112
73
541
1.55
2.23
4.8
3.3
39.62
58.16
e6/l
0.23
53
377
5
9
5.66
2.22
1.8
1.1
4.92
8.30
mmol/l
—
5
9
61
436
1.57
2.17
4.1
3.5
0.00
0.00
estimate
—
9
148
84
648
1.51
2.11
2.1
2.0
—
—
—
0
0
22
119
1.95
2.07
6.1
4.1
0.55
0.36
%
0.12
11
28
20
106
1.98
1.99
2.2
2.1
67.94
67.86
g/l
0.02
20
98
11
45
2.53
1.96
1.3
1.3
—
—
—
0
0
133
1137
1.49
1.95
4.9
3.9
—
—
—
0
0
22
122
1.90
1.93
6.5
4.2
0.00
0.12
%
1.36
11
33
37
244
1.63
1.82
1.9
1.6
986.86
1163.98
nmol/l
0.75
32
189
8
29
2.83
1.81
1.3
1.2
—
—
—
0
0
11
48
2.37
1.74
1.8
1.6
—
—
—
0
0
42
290
1.57
1.72
3.7
2.6
482.19
550.20
mosm/kgh2o
1.39
36
251
198
1900
2.71
1.70
23.9
17.3
40.50
40.52
%
0.02
180
1779
25
152
1.74
1.66
1.6
1.7
374.56
381.78
nmol/l
0.08
25
139
32
209
1.63
1.64
1.6
1.6
—
—
—
0
0
6
20
3.06
1.59
1.3
1.3
—
—
—
0
0
25
154
1.71
1.59
5.3
10.4
0.98
1.28
mmol/l
0.14
19
123
33
220
1.60
1.56
4.1
2.1
14.07
14.21
umol/l
0.04
33
201
59
452
1.43
1.46
2.8
2.6
—
—
—
0
0
5
16
3.18
1.44
3.0
2.2
—
—
—
0
0
61
471
1.42
1.44
4.0
2.8
—
—
—
0
0
40
287
1.49
1.38
1.6
1.8
393.91
466.62
pmol/l
0.58
33
255
6
23
2.66
1.37
1.0
1.2
—
—
—
0
0
6
23
2.66
1.37
1.0
1.1
—
—
—
0
0
13
68
1.97
1.36
1.2
1.4
—
1.92
—
0
5
15
83
1.87
1.35
2.4
10.7
—
—
—
0
0
8
34
2.41
1.30
1.0
1.1
—
—
—
0
0
5
18
2.82
1.29
1.4
1.2
—
—
—
0
0
21
134
1.63
1.20
1.4
1.4
—
—
—
0
0
6
26
2.35
1.19
3.2
3.3
57.50
61.04
%
—
6
26
6
26
2.35
1.19
3.2
3.2
3.94
4.77
e9/l
—
6
26
10
50
2.05
1.18
2.7
1.6
—
—
—
0
0
76
627
1.34
1.18
5.4
4.4
37.07
36.10
g/l
1.22
71
593
13
73
1.83
1.13
7.1
14.4
—
—
—
0
0
46
353
1.39
1.12
1.4
1.3
2.07
2.26
g/l
0.29
30
223
29
205
1.48
1.08
1.6
1.5
—
—
—
0
0
7
33
2.16
1.06
3.6
1.5
—
—
—
0
0
95
821
1.30
1.03
6.2
5.4
0.57
0.55
e9/l
0.24
90
726
95
822
1.29
1.02
6.3
5.4
0.04
0.04
e9/l
0.32
90
726
13
76
1.76
1.01
2.2
1.4
—
—
—
0
0
33
243
1.43
1.01
2.6
3.4
0.82
0.82
mmol/l
0.12
33
232
5
23
2.20
0.98
1.0
1.3
—
—
—
0
0
26
356
0.69
0.97
2.9
3.5
—
—
—
0
0
12
70
1.76
0.95
1.5
1.5
—
—
—
0
0
26
186
1.46
0.93
1.3
1.2
—
—
—
0
0
108
958
1.27
0.93
7.1
8.6
3.88
3.96
e9/l
0.15
101
848
14
87
1.65
0.90
1.4
1.3
294.10
484.16
u/ml
0.24
14
75
140
1506
0.77
0.90
18.6
15.0
333.93
333.07
g/l
0.51
140
1499
20
137
1.51
0.88
1.6
2.4
0.25
0.22
g/l
1.37
20
125
49
395
1.32
0.87
5.1
6.3
—
—
—
0
0
25
180
1.44
0.87
2.3
1.5
—
—
—
0
0
39
305
1.34
0.85
1.6
1.6
—
—
—
0
0
56
463
1.29
0.83
4.7
3.6
11.01
11.00
mg/mmol
0.00
38
287
96
848
1.25
0.83
6.2
5.5
1.94
1.96
e9/l
0.03
90
769
18
123
1.51
0.81
1.5
1.3
—
—
—
0
0
7
125
0.54
0.80
8.0
3.1
—
—
—
0
0
11
66
1.70
0.80
2.5
1.4
—
—
—
0
0
13
82
1.63
0.80
2.3
1.4
—
—
—
0
0
13
82
1.63
0.80
2.5
1.4
—
—
—
0
0
55
457
1.28
0.79
3.7
2.7
13.48
185.76
e6/l
0.66
46
353
25
184
1.41
0.78
1.5
1.4
—
—
—
0
0
95
843
1.24
0.77
6.3
5.8
0.20
0.18
e9/l
0.50
89
758
13
83
1.61
0.77
2.5
1.4
—
—
—
0
0
13
83
1.61
0.77
2.3
1.4
—
—
—
0
0
5
24
2.11
0.75
4.0
1.9
—
—
—
0
0
5
25
2.02
0.73
2.2
1.6
—
—
—
0
0
9
57
1.61
0.72
3.2
2.8
—
—
—
0
0
91
809
1.23
0.72
3.8
3.3
0.00
0.00
estimate
—
10
162
7
44
1.61
0.66
1.0
1.2
—
—
—
0
0
51
431
1.24
0.63
3.7
3.2
116.56
376.54
mg/l
0.62
40
283
14
96
1.49
0.63
3.2
3.8
4.56
4.57
pmol/l
0.01
14
87
87
779
1.20
0.62
7.5
5.8
—
—
—
0
0
8
51
1.59
0.61
1.0
1.2
—
—
—
0
0
14
98
1.46
0.58
1.1
1.2
—
—
—
0
0
54
465
1.22
0.57
1.4
1.5
—
—
—
0
0
12
82
1.49
0.55
1.0
1.1
—
—
—
0
0
121
1126
1.18
0.54
3.1
3.6
—
—
—
0
0
6
40
1.51
0.52
2.5
3.3
—
—
—
0
0
39
459
0.81
0.51
9.8
3.3
7.39
7.40
ph
—
5
76
10
68
1.49
0.48
1.3
1.2
—
—
—
0
0
41
352
1.21
0.45
2.4
1.6
1.16
1.00
mg/l
0.25
33
279
9
126
0.70
0.45
1.4
1.4
—
—
—
0
0
5
31
1.63
0.43
1.4
1.3
—
—
—
0
0
8
57
1.42
0.42
1.4
1.2
—
—
—
0
0
8
60
1.35
0.41
2.0
2.1
1.58
1.41
g/l
—
8
55
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
17
134
1.29
0.38
1.1
1.3
69.00
142.43
iu/ml
—
5
59
26
218
1.22
0.36
1.3
1.3
—
—
—
0
0
5
76
0.65
0.36
2.8
3.2
—
—
—
0
0
11
82
1.36
0.35
1.9
1.3
29.85
24.76
iu/l
0.20
11
70
6
44
1.37
0.34
1.2
3.8
—
—
—
0
0
33
287
1.18
0.32
3.9
3.4
12.41
234.45
ng/l
1.24
22
209
12
93
1.31
0.30
1.3
1.3
—
—
—
0
0
14
112
1.27
0.29
1.1
1.3
—
25.93
—
0
6
37
409
0.88
0.24
3.1
2.5
—
—
—
0
0
14
115
1.23
0.24
2.6
3.5
—
—
—
0
0
5
40
1.26
0.22
3.8
2.2
1134.04
97.68
ug/min
—
5
21
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
179.07
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
6
48
1.26
0.20
1.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
3.4
—
43.66
—
0
7
15
127
1.20
0.20
1.3
1.3
—
—
—
0
0
39
422
0.91
0.18
3.2
2.6
0.04
0.37
e6/l
2.84
32
320
22
197
1.13
0.16
1.5
1.8
—
—
—
0
0
8
72
1.12
0.16
2.1
2.2
—
—
—
0
0
10
83
1.22
0.15
10.9
5.7
23.65
25.02
mmol/l
—
10
83
29
269
1.09
0.12
3.2
2.7
0.68
0.70
ug/l
0.07
21
162
10
116
0.85
0.12
22.5
6.6
—
—
—
0
0
12
105
1.15
0.11
1.9
1.8
—
—
—
0
0
41
389
1.07
0.10
1.7
1.9
—
—
—
0
0
19
174
1.10
0.10
1.3
1.5
—
—
—
0
0
84
817
1.05
0.09
3.9
3.4
0.00
0.00
estimate
—
10
145
83
808
1.05
0.09
4.8
4.6
0.00
0.00
estimate
—
10
151
21
226
0.92
0.08
1.3
1.8
—
—
—
0
0
6
71
0.84
0.08
8.8
2.1
1.12
1.37
%
—
6
71
6
71
0.84
0.08
1.0
1.1
—
—
—
0
0
73
711
1.04
0.07
9.4
8.7
0.00
0.00
e9/l
0.53
66
585
64
623
1.04
0.06
2.7
2.6
—
—
—
0
0
22
210
1.05
0.04
1.7
1.4
—
—
—
0
0
18
171
1.06
0.03
9.0
6.2
105.44
104.20
mmol/l
0.74
18
171
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.6
279.67
278.00
mu/l
—
6
62
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
68
0.88
-0.00
8.8
2.2
0.55
0.68
%
—
6
68
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
58.33
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
10.6
—
24.06
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
3.36
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
6.32
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
1949.00
—
0
5
5
52
0.96
-0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_HAND – Hand

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).