Other protozoal intestinal diseases

AB1_OTHER_PROTOZOAL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A07
  • Hospital discharge: ICD-9 007.
  • Hospital discharge: ICD-8 00[7]
  • Cause of death: ICD-10 A07
  • Cause of death: ICD-9 007.
  • Cause of death: ICD-8 00[7]

2 out of 7 registries used, show all original rules.

561

4. Check minimum number of events

None

561

5. Include endpoints

None

561

6. Filter based on genotype QC (FinnGen only)

534

Control definitions (FinnGen only)

Control exclude
AB1_INTESTINAL_INFECTIONS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4130 2179 1912
Only index persons 3443 1892 1551
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.05
Only index persons 0.06 0.07 0.06
Median age at first event (years)
Whole population 32.48 34.90 29.57
Only index persons 34.41 35.94 32.55

-FinnGen-

Key figures

All Female Male
Number of individuals 534 347 187
Unadjusted period prevalence (%) 0.11 0.12 0.09
Median age at first event (years) 45.56 43.12 50.08

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
561
Matched controls
5610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A07.8
ICD-10 Finland
Other specified protozoal intestinal diseases
+∞
285.6
249
*
A07.1
ICD-10 Finland
Giardiasis [lambliasis]
1520.7
128.4
120
*
P01AB01
ATC
metronidazole; oral, rectal
6.9
103.6
408
1562
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
7.4
103.2
191
365
A07.9
ICD-10 Finland
Protozoal intestinal disease, unspecified
+∞
78.0
73
*
00710
ICD-8 Finland
Other protozoal intestinal diseases, Giardiasis
+∞
54.0
51
*
A07.2
ICD-10 Finland
Cryptosporidiosis
+∞
42.2
40
*
K59.1
ICD-10 Finland
Functional diarrhoea
6.5
34.1
59
100
D11
ICPC
Diarrhoea
3.4
26.7
111
377
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
26.0
261
1421
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
4.4
23.5
63
157
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
5.5
21.1
42
81
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
+∞
21.0
20
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
5.3
19.3
40
80
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
18.9
174
886
UJF30
NOMESCO Finland
Ileoscopy through colon
3.3
18.7
78
263
Z2221
NOMESCO Finland
Medical doctor
2.3
18.7
196
1055
A02BC05
ATC
esomeprazole; systemic
2.2
17.6
248
1497
D01
ICPC
Abdominal pain/cramps general
2.8
16.9
94
373
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.2
16.6
187
1029
A06AC01
ATC
ispaghula (psylla seeds); oral
2.3
16.3
160
830
UJF32
NOMESCO Finland
Coloscopy
2.3
15.9
153
786
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
6.7
15.5
25
39
C10AC01
ATC
colestyramine; oral
6.3
15.2
26
43
Z71.8
ICD-10 Finland
Other specified counselling
2.1
14.1
207
1245
A04
ICPC
Weakness/tiredness general
2.5
13.6
96
427
00799
ICD-8 Finland
Other protozoal intestinal diseases, Other and unspecified
+∞
13.6
13
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.5
13.0
94
423
J02AC01
ATC
fluconazole; systemic
1.9
11.9
243
1617
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
11.3
219
1425
R4110
NOMESCO Finland
Physiotherapy
2.0
11.3
162
954
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.6
11.1
66
269
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
11.1
154
896
R53
ICD-10 Finland
Malaise and fatigue
2.0
10.7
146
843
Z01.7
ICD-10 Finland
Laboratory examination
2.2
10.7
98
487
A04.9
ICD-10 Finland
Bacterial intestinal infection, unspecified
61.2
10.7
12
*
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
+∞
10.4
10
*
0071A
ICD-9 Finland
Other protozoal intestinal diseases, Giardiasis
+∞
10.4
10
*
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
+∞
10.4
10
*
J01MA02
ATC
ciprofloxacin; systemic
1.8
10.3
201
1303
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.5
10.1
65
276
ZXE00
NOMESCO Finland
One hour or less
1.8
10.0
226
1530
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.2
9.7
94
476
A02BC02
ATC
pantoprazole; systemic
1.8
9.6
353
2739
E0000UV, ,
ATC
1.8
9.4
235
1630
A06
ICD-10 Finland
Amoebiasis
+∞
9.4
9
*
A06.9
ICD-10 Finland
Amoebiasis, unspecified
+∞
9.4
9
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.3
9.1
72
336
D06
ICPC
Abdominal pain localized other
2.5
9.0
56
234
Z3231
NOMESCO Finland
Registered nurse
1.8
8.7
156
977
R51.80
ICD-10 Finland
Headache
2.0
8.6
106
587
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
6.6
8.6
21
33
A02BC01
ATC
omeprazole; systemic
1.8
8.4
146
904
J01MA06
ATC
norfloxacin; oral
2.2
8.4
75
367
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
8.4
104
577
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
8.2
142
879
UJF30, ,
SPAT
11.9
8.1
14
12
EB1AA, ,
SPAT
2.5
8.1
53
227
D96
ICPC
Worms/other parasites
22.4
8.0
11
5
L08
ICPC
Shoulder symptom/complaint
1.9
8.0
118
694
R19.4
ICD-10 Finland
Change in bowel habit
4.2
7.9
21
52
N02AX02
ATC
tramadol; systemic, rectal
1.7
7.7
215
1516
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.6
7.7
18
40
H01.0
ICD-10 Finland
Blepharitis
2.5
7.6
47
195
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
7.6
103
587
N06AX11
ATC
mirtazapine; oral
1.7
7.5
183
1245
A06.8
ICD-10 Finland
Amoebic infection of other sites
81.1
7.4
8
*
R03AC02
ATC
salbutamol; inhalant
1.6
7.4
311
2426
A07
ICD-10 Finland
Other protozoal intestinal diseases
+∞
7.3
7
*
00000, ,
ICD-8 Finland
+∞
7.3
7
*
A02BA02
ATC
ranitidine; systemic
1.9
7.2
95
537
Z3226
NOMESCO Finland
Physiotherapist
1.9
7.1
102
594
XQ800
NOMESCO Finland
Prick test
2.3
7.0
51
229
R83
ICPC
Respiratory infection other
1.7
6.9
167
1131
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.8
6.9
109
654
J01FA06
ATC
roxithromycin; oral
1.6
6.8
212
1528
L01
ICPC
Neck symptom/complaint
1.9
6.7
92
527
E61.1
ICD-10 Finland
Iron deficiency
3.7
6.6
21
59
K30
ICD-10 Finland
Functional dyspepsia
2.1
6.6
65
331
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.5
6.5
22
65
M79.6
ICD-10 Finland
Pain in limb
1.6
6.5
219
1606
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.1
6.4
60
299
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
6.4
84
473
R42
ICD-10 Finland
Dizziness and giddiness
1.8
6.4
109
667
UJF92
NOMESCO Finland
Capsular endoscopy
5.3
6.4
18
35
JN3AE, ,
SPAT
3.4
6.3
22
66
A07.0
ICD-10 Finland
Balantidiasis
+∞
6.3
6
*
0078A
ICD-9 Finland
Other protozoal intestinal diseases, Other specified protozoal intestinal diseases[CRYPTOSPORIDIOSIS]
+∞
6.3
6
*
N03AX16
ATC
[U] pregabalin
1.7
6.1
113
707
L92
ICPC
Shoulder syndrome
4.2
6.1
16
39
A06AC51
ATC
ispaghula, combinations; oral
2.7
6.1
31
117

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
305
141
46.21
307.65
4.2
1.6
—
—
—
0
0
234
568
6.35
98.54
2.4
2.4
79.57
100.05
ug/g
0.79
191
443
84
120
8.06
57.51
1.3
1.2
—
—
—
0
0
107
219
5.80
51.56
1.5
1.2
—
—
—
0
0
258
1079
3.58
47.64
1.5
1.3
2.49
1.94
u/ml
0.13
41
268
237
997
3.38
42.37
1.6
1.4
2.11
2.26
g/l
0.67
114
618
146
452
4.01
41.65
1.3
1.3
—
—
—
0
0
134
393
4.17
41.17
1.2
1.2
—
—
—
0
0
58
103
6.17
31.96
1.6
1.3
302.24
311.46
ug/g
0.11
42
53
347
2044
2.83
31.09
6.2
6.0
0.74
0.68
%
1.35
327
1912
377
2329
2.89
30.62
6.1
5.9
2.12
1.99
e9/l
0.27
307
2082
359
2167
2.82
30.41
6.2
5.8
53.94
56.80
%
5.10
342
2045
368
2252
2.84
30.31
6.1
5.9
0.55
0.56
e9/l
0.45
285
1963
361
2191
2.82
30.15
6.4
6.0
30.86
28.80
%
3.25
344
2071
352
2121
2.77
29.61
6.5
6.2
8.50
8.38
%
0.37
333
1996
367
2261
2.80
29.51
6.1
5.9
0.04
0.04
e9/l
0.26
285
1970
141
527
3.24
29.23
1.3
1.2
—
—
—
0
0
350
2112
2.75
29.20
6.3
5.9
3.15
2.83
%
1.32
331
1984
372
2343
2.74
28.01
6.2
6.1
0.20
0.19
e9/l
0.57
300
2072
344
2128
2.59
26.15
5.7
6.4
—
—
—
0
0
391
2582
2.70
25.78
7.7
9.0
3.63
4.01
e9/l
3.30
310
2261
216
1096
2.58
24.67
2.4
1.9
—
—
—
0
0
108
388
3.21
23.55
1.9
2.4
29.66
35.32
u/l
0.84
98
336
325
2019
2.45
23.54
8.6
8.9
0.00
0.00
e9/l
0.29
217
1642
448
3315
2.74
20.97
7.6
6.8
70.86
78.43
u/l
3.17
428
3106
81
285
3.15
18.07
1.4
1.2
—
—
—
0
0
270
1678
2.17
17.88
4.4
4.4
36.40
36.26
g/l
0.17
252
1584
255
1578
2.13
16.78
2.2
1.8
95.67
95.33
pmol/l
0.04
136
834
200
1135
2.18
16.36
2.5
2.7
—
—
—
0
0
248
1531
2.11
16.29
3.4
3.4
21.91
70.48
e6/l
3.50
150
1010
194
1101
2.16
15.76
5.6
6.7
—
—
—
0
0
200
1152
2.14
15.62
2.9
2.8
0.20
0.37
e6/l
1.39
132
841
68
254
2.91
13.57
1.1
1.2
—
147.00
titre
—
0
8
305
2133
1.94
13.21
5.6
6.0
11.57
10.77
umol/l
0.77
290
2030
422
3320
2.09
12.77
4.5
3.8
8.28
10.83
mm/h
5.49
403
3066
102
480
2.38
12.74
2.4
2.7
7.07
7.11
umol/l
0.01
84
419
203
1263
1.95
12.23
2.9
2.9
42.37
63.91
e6/l
0.54
136
930
130
701
2.11
11.59
2.6
2.6
0.42
0.93
e6/l
3.97
61
396
52
187
2.96
11.08
2.4
2.4
—
—
—
0
0
129
709
2.06
10.87
2.7
2.8
2.41
2.44
mmol/l
1.63
108
624
290
2100
1.79
10.29
3.8
2.7
78.70
99.86
ug/l
2.19
274
1956
253
1764
1.79
10.17
2.1
2.0
—
—
—
0
0
520
4584
2.84
10.09
15.3
11.5
20.27
21.67
mg/l
0.44
389
3521
166
1028
1.87
9.76
2.8
2.1
2.51
2.94
mg/l
1.74
146
877
119
668
1.99
9.34
2.7
2.7
1.20
2.36
e6/l
2.72
52
367
208
1396
1.78
9.32
2.6
2.9
2.35
2.35
mmol/l
0.17
183
1246
113
626
2.01
9.20
2.5
2.2
14.72
13.92
umol/l
0.38
107
579
182
1192
1.78
8.77
3.2
3.6
7.38
7.40
ph
0.85
25
214
477
4115
2.06
8.68
17.2
14.0
14.03
14.65
%
2.19
471
4061
386
3119
1.76
8.64
5.0
3.8
—
—
—
0
0
252
1821
1.70
8.47
2.5
2.2
80.45
75.09
nmol/l
2.14
224
1658
103
571
1.98
8.32
2.6
2.1
2.33
2.41
g/l
0.67
95
523
136
830
1.84
8.21
2.1
2.3
6.17
6.67
e6/l
0.10
114
732
70
342
2.20
7.88
2.8
2.6
11.00
10.15
g/l
1.00
57
317
145
914
1.79
7.83
1.5
1.5
22.83
21.30
nmol/l
0.67
133
786
485
4256
2.03
7.71
5.3
4.5
1.73
2.12
mu/l
0.77
463
3936
96
533
1.97
7.69
2.7
2.2
25.63
23.22
%
0.62
87
463
265
1999
1.62
7.16
5.6
6.7
1.21
1.21
mmol/l
0.02
238
1710
28
91
3.19
7.11
1.1
1.2
—
—
—
0
0
510
4589
2.22
7.11
14.8
12.9
139.52
139.72
mmol/l
1.21
505
4458
155
1024
1.71
7.01
3.2
3.2
—
—
—
0
0
19
48
4.06
6.94
1.1
1.0
—
—
—
0
0
420
3573
1.70
6.78
4.4
3.8
14.40
14.56
pmol/l
0.80
391
3279
510
4605
2.18
6.78
15.2
13.0
3.88
3.95
mmol/l
8.82
505
4464
127
801
1.76
6.75
3.3
2.7
546.21
554.72
mosm/kgh2o
0.15
98
675
70
368
2.03
6.51
1.4
1.5
—
—
—
0
0
14
20
7.15
6.25
1.1
1.2
—
—
—
0
0
240
1816
1.56
6.11
4.3
6.1
1.21
1.22
mmol/l
0.10
230
1666
360
2984
1.58
6.09
3.5
3.3
—
—
—
0
0
144
966
1.66
6.04
1.8
1.9
1.52
1.06
mg/l
0.57
105
731
38
162
2.44
5.87
1.9
1.6
—
—
—
0
0
21
67
3.22
5.52
1.2
1.1
—
—
—
0
0
55
284
2.04
5.38
1.7
1.7
1.21
1.46
g/l
0.70
49
266
199
1481
1.53
5.28
3.2
3.0
32.47
29.98
u/l
0.34
191
1414
112
728
1.67
5.24
3.2
3.6
1367.26
366.71
ng/l
0.37
75
521
98
615
1.72
5.22
3.1
3.6
0.83
0.82
mmol/l
0.44
93
592
173
1264
1.53
4.94
2.9
2.3
55.25
62.01
u/l
0.87
162
1173
16
47
3.47
4.78
1.6
1.3
—
—
—
0
0
119
815
1.58
4.48
1.2
1.3
31.65
35.21
iu/ml
0.13
25
265
24
96
2.57
4.27
1.2
1.3
230.40
242.52
u/ml
0.06
15
50
33
155
2.20
4.14
1.5
2.4
1.21
1.35
g/l
0.44
27
137
156
1155
1.49
4.07
1.6
1.6
1.10
1.37
mmol/l
6.24
133
979
95
637
1.59
3.89
1.4
1.3
367.50
400.94
titre
0.12
16
128
180
1383
1.44
3.86
2.1
2.2
—
—
—
0
0
270
2232
1.40
3.83
5.6
4.5
0.00
0.00
estimate
0.50
45
430
10
20
5.07
3.70
2.4
2.4
—
—
—
0
0
10
20
5.07
3.70
1.0
1.2
158.08
153.32
nmol/l
—
10
20
271
2255
1.39
3.63
3.9
3.3
0.00
0.01
estimate
0.50
44
418
78
507
1.63
3.63
1.4
1.4
—
—
—
0
0
225
1816
1.40
3.61
3.6
3.0
6.17
5.90
ph
0.72
23
148
52
303
1.79
3.59
1.2
1.2
193.77
153.48
u/ml
0.29
45
273
34
175
2.00
3.41
1.2
1.3
—
—
—
0
0
12
32
3.81
3.40
2.5
2.4
—
—
—
0
0
13
42
3.14
3.39
1.1
1.2
—
—
—
0
0
111
794
1.50
3.39
1.2
1.3
5.36
11.84
u/ml
0.91
38
298
266
2230
1.37
3.30
3.9
3.3
0.02
0.00
estimate
0.43
43
454
55
335
1.71
3.28
1.7
1.4
—
—
—
0
0
86
587
1.55
3.26
2.0
1.5
—
—
—
0
0
24
111
2.21
3.17
2.9
2.7
—
—
—
0
0
63
402
1.64
3.16
2.1
3.0
1.48
1.73
%
2.62
53
369
67
439
1.60
3.03
1.4
1.4
—
—
—
0
0
9
21
4.34
3.00
1.1
1.5
—
—
—
0
0
139
1063
1.41
2.97
2.1
2.2
—
—
—
0
0
351
3104
1.35
2.93
3.5
2.9
38.56
42.55
u/l
0.39
330
2933
93
661
1.49
2.92
1.9
1.7
1065.77
1163.89
nmol/l
0.50
65
499
21
96
2.23
2.87
1.2
1.5
—
—
—
0
0
18
78
2.35
2.77
2.6
3.0
—
—
—
0
0
514
4878
1.64
2.73
11.7
9.2
24.25
26.01
u/l
2.13
507
4718
248
2102
1.32
2.70
2.5
2.5
—
—
—
0
0
17
73
2.37
2.67
3.7
2.6
2.54
2.75
mmol/l
—
8
43
64
428
1.56
2.67
1.9
2.0
372.14
370.26
nmol/l
0.03
58
399
46
284
1.68
2.64
3.0
3.3
4.47
4.58
pmol/l
0.42
36
248
30
164
1.88
2.58
1.2
1.2
—
—
—
0
0
16
68
2.39
2.58
1.2
1.0
—
—
—
0
0
5
7
7.19
2.55
1.8
1.3
—
—
—
0
0
15
64
2.38
2.40
2.4
2.7
16.94
16.27
%
—
9
38
8
22
3.67
2.37
1.4
1.2
20.75
22.79
umol/l
—
8
22
19
91
2.13
2.35
1.2
2.0
—
—
—
0
0
53
351
1.56
2.32
2.8
4.4
3.21
19.67
ug/l
0.74
37
285
147
1182
1.33
2.25
2.3
2.0
128.99
256.92
u/l
1.45
138
1108
83
609
1.43
2.22
1.6
2.3
30.26
29.37
s
1.01
83
597
11
41
2.72
2.21
1.0
1.1
—
—
—
0
0
36
220
1.68
2.18
1.2
1.1
—
—
—
0
0
125
986
1.34
2.17
4.2
3.9
—
—
—
0
0
278
2445
1.27
2.12
4.0
4.7
6.18
6.56
mmol/l
2.48
260
2241
126
1006
1.33
2.01
2.7
3.0
730.91
1203.04
ng/l
2.05
97
853
9
32
2.84
2.01
3.2
1.6
—
—
—
0
0
16
77
2.11
1.98
1.4
1.1
—
—
—
0
0
113
891
1.34
1.96
1.8
1.6
—
—
—
0
0
67
485
1.43
1.95
2.1
1.5
—
—
—
0
0
5
11
4.58
1.94
1.2
2.9
—
—
—
0
0
46
310
1.53
1.90
1.9
2.4
3.87
6.68
e9/l
1.23
41
262
7
22
3.21
1.88
1.4
1.0
—
—
—
0
0
16
79
2.06
1.87
2.3
1.7
—
—
—
0
0
8
28
2.88
1.87
1.0
1.3
—
—
—
0
0
19
102
1.89
1.78
1.1
1.1
1.52
0.67
u/ml
0.59
13
50
6
18
3.36
1.75
1.0
1.0
—
—
—
0
0
47
325
1.49
1.74
4.2
9.4
—
—
—
0
0
5
13
3.87
1.72
1.0
1.5
—
—
—
0
0
17
89
1.94
1.71
3.8
2.7
7.42
7.42
ph
0.08
17
74
52
369
1.45
1.70
1.1
1.2
137.81
157.92
iu/ml
0.10
11
165
8
31
2.60
1.66
1.9
1.5
188.88
181.38
pmol/l
—
8
31
19
106
1.82
1.60
1.1
1.1
—
—
—
0
0
11
50
2.22
1.58
2.5
1.3
—
—
—
0
0
458
4351
1.29
1.52
4.3
4.1
5.65
5.80
mmol/l
1.94
418
4007
7
28
2.52
1.45
2.3
1.4
—
—
—
0
0
7
28
2.52
1.45
1.7
1.2
—
—
—
0
0
164
1407
1.23
1.45
1.6
1.5
—
—
—
0
0
5
16
3.14
1.44
1.0
1.0
—
—
—
0
0
505
4874
1.36
1.40
12.6
10.7
—
—
—
0
0
26
166
1.59
1.40
1.6
3.5
0.16
0.21
g/l
0.61
13
73
41
567
0.70
1.39
1.2
1.3
—
—
—
0
0
13
67
1.96
1.39
1.2
1.2
—
—
—
0
0
42
299
1.44
1.38
2.0
3.0
59.04
71.60
e9/l
1.92
29
229
9
41
2.21
1.37
1.0
2.8
—
—
—
0
0
6
23
2.63
1.37
1.2
1.2
—
—
—
0
0
40
283
1.45
1.36
1.9
1.4
17.06
22.91
iu/l
0.79
33
234
18
105
1.74
1.34
2.8
2.4
—
—
—
0
0
0
39
0.00
1.34
0.0
3.1
—
19.22
—
0
27
534
5209
1.52
1.33
22.2
17.2
252.73
254.78
e9/l
0.32
524
5078
21
129
1.65
1.31
2.0
2.6
—
—
—
0
0
71
557
1.31
1.31
1.2
1.2
—
—
—
0
0
6
24
2.52
1.30
1.0
1.4
1.61
1.54
g/l
—
6
24
534
5212
1.51
1.29
22.2
17.2
4.49
4.52
e12/l
1.05
522
5066
148
1705
0.82
1.27
2.8
2.5
—
—
—
0
0
83
668
1.28
1.27
2.3
1.6
—
—
—
0
0
534
5214
1.50
1.26
22.3
17.2
6.48
6.66
e9/l
0.69
523
5065
47
351
1.37
1.20
3.7
5.1
1.46
2.08
mmol/l
0.72
41
287
533
5208
1.47
1.18
22.2
17.4
40.42
40.31
%
0.23
519
4927
11
57
1.95
1.17
5.0
2.7
—
—
—
0
0
10
50
2.02
1.17
1.0
2.7
—
—
—
0
0
0
36
0.00
1.14
0.0
17.3
—
1654.97
—
0
36
0
36
0.00
1.14
0.0
13.3
—
906.67
—
0
36
14
80
1.77
1.14
1.7
7.7
—
—
—
0
0
22
143
1.56
1.13
1.5
1.8
0.80
3.28
ug/l
0.68
17
128
168
1480
1.19
1.11
3.6
3.0
23.87
41.25
ng/l
1.52
90
930
13
73
1.80
1.11
1.2
1.3
0.58
0.52
nmol/l
0.31
13
68
5
21
2.39
1.09
1.2
1.0
—
—
—
0
0
38
280
1.38
1.07
2.2
2.6
—
—
—
0
0
25
170
1.49
1.06
1.4
1.3
—
—
—
0
0
126
1086
1.21
1.06
2.0
2.6
308.52
7317.62
umol/l
4.81
108
962
33
238
1.41
1.05
2.0
2.5
—
—
—
0
0
25
171
1.48
1.04
1.4
1.3
—
—
—
0
0
9
46
1.97
1.04
3.4
3.3
—
—
—
0
0
5
22
2.28
1.03
1.0
1.5
—
—
—
0
0
23
155
1.50
1.02
1.4
2.2
—
—
—
0
0
5
110
0.45
1.01
1.4
3.8
3.42
3.92
mmol/l
—
5
110
81
671
1.24
1.00
3.0
2.9
0.51
0.72
ug/l
4.19
62
431
57
453
1.29
0.99
5.6
8.0
105.23
104.06
mmol/l
1.18
57
453
14
85
1.66
0.95
1.9
1.6
198.29
234.10
pmol/l
0.46
14
78
140
1233
1.18
0.93
2.9
2.7
—
—
—
0
0
25
176
1.44
0.92
1.4
1.4
—
—
—
0
0
6
30
2.01
0.87
1.0
1.5
0.84
0.97
g/l
—
6
30
39
300
1.32
0.87
1.5
1.6
—
—
—
0
0
19
130
1.48
0.82
1.3
1.1
—
—
—
0
0
25
181
1.40
0.81
1.2
1.2
—
2.18
—
0
13
38
295
1.31
0.81
2.9
2.1
4.64
7.77
ug/l
0.88
30
265
14
211
0.65
0.80
4.1
8.9
23.16
24.59
mmol/l
0.66
14
203
26
193
1.36
0.74
1.4
1.4
354.00
254.25
miu/ml
0.53
12
101
5
26
1.93
0.71
1.2
1.0
401.00
219.13
ng/l
—
5
15
11
69
1.61
0.69
1.9
7.5
53.36
62.13
%
0.64
11
69
31
395
0.77
0.68
5.9
9.4
0.47
1.26
mmol/l
0.65
25
327
31
395
0.77
0.68
6.0
9.4
4.84
5.21
kpa
1.03
31
383
5
27
1.86
0.68
2.2
2.9
325.60
717.22
u/ml
—
5
27
10
156
0.63
0.68
5.6
7.9
—
—
—
0
0
189
1743
1.13
0.66
14.2
11.7
1.22
1.20
inr
0.10
54
536
5
29
1.73
0.64
1.2
1.3
17.90
33.07
nmol/l
—
5
23
26
199
1.32
0.63
7.0
3.3
—
—
—
0
0
103
1154
0.87
0.63
3.8
3.6
8.25
10.27
mg/mmol
0.18
65
721
27
345
0.77
0.62
5.7
9.9
123.85
120.62
g/l
0.30
27
337
36
290
1.26
0.61
2.0
2.7
66.17
66.94
g/l
0.29
31
268
14
97
1.45
0.59
1.5
2.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
6.28
—
0
23
13
89
1.47
0.58
1.3
1.1
—
—
—
0
0
13
89
1.47
0.58
1.3
1.1
—
—
—
0
0
8
54
1.49
0.57
1.4
1.4
—
—
—
0
0
8
54
1.49
0.57
1.4
1.2
—
—
—
0
0
18
240
0.74
0.56
6.3
9.7
1.24
1.38
%
0.26
18
240
18
240
0.74
0.56
6.7
9.8
0.81
0.67
%
0.51
18
240
28
221
1.28
0.56
1.0
1.1
—
—
—
0
0
11
73
1.52
0.56
3.0
3.1
—
—
—
0
0
8
124
0.64
0.55
1.1
1.3
—
—
—
0
0
29
360
0.79
0.54
5.4
9.8
96.12
95.99
%
0.07
29
351
17
125
1.37
0.54
1.3
2.2
11.56
11.95
mg/l
0.07
17
114
11
74
1.50
0.53
1.2
1.1
—
—
—
0
0
416
4039
1.12
0.52
4.9
5.0
37.14
38.71
mmol/mol
4.46
391
3787
21
162
1.31
0.50
1.5
1.4
9.90
9.75
u/l
0.02
14
125
39
326
1.21
0.50
2.7
3.2
—
—
—
0
0
7
46
1.53
0.48
2.1
2.6
—
—
—
0
0
7
47
1.50
0.47
1.9
6.4
7.21
6.75
mmol/l
—
7
38
123
1131
1.11
0.46
3.3
3.4
—
—
—
0
0
65
576
1.15
0.44
1.9
1.8
—
—
—
0
0
19
149
1.28
0.42
1.1
1.2
—
—
—
0
0
36
305
1.19
0.42
5.6
4.9
0.38
0.53
%
0.38
17
95
420
4297
0.91
0.41
3.7
3.6
1.11
1.25
mmol/l
5.96
393
3984
0
16
0.00
0.41
0.0
1.0
—
15.09
—
0
11
30
251
1.21
0.40
2.0
2.2
6417.61
2870.31
u/l
0.24
13
105
10
71
1.42
0.39
2.0
2.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.2
1.2
—
—
—
0
0
6
42
1.43
0.35
1.3
1.1
—
—
—
0
0
117
1254
0.92
0.35
2.7
3.0
8.09
7.78
mmol/l
0.25
106
1066
38
330
1.16
0.35
1.3
1.4
—
—
—
0
0
43
378
1.15
0.34
4.5
3.3
—
—
—
0
0
133
1252
1.08
0.31
3.8
2.9
—
—
—
0
0
7
53
1.32
0.31
1.0
1.3
—
—
—
0
0
18
218
0.82
0.31
3.2
6.8
—
—
—
0
0
11
84
1.32
0.30
1.3
1.2
—
—
—
0
0
10
130
0.77
0.29
2.9
4.2
—
—
—
0
0
77
832
0.91
0.28
1.9
1.6
456.57
33522361.20
pmol/l
1.30
67
707
102
1087
0.92
0.28
2.9
3.1
58.16
370.98
mg/l
1.60
60
691
36
319
1.14
0.27
5.8
5.1
0.00
0.15
%
3.08
15
98
64
589
1.10
0.26
2.2
1.9
—
—
—
0
0
9
73
1.24
0.25
1.0
1.6
—
—
—
0
0
38
340
1.13
0.25
5.6
4.9
0.50
0.99
%
1.13
18
120
26
228
1.15
0.23
1.5
1.6
—
—
—
0
0
26
229
1.14
0.22
1.5
1.6
—
—
—
0
0
26
229
1.14
0.22
1.5
1.6
—
—
—
0
0
5
41
1.22
0.22
1.4
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
7.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
26
230
1.14
0.21
1.5
1.6
—
—
—
0
0
24
211
1.14
0.21
1.5
1.6
—
—
—
0
0
6
48
1.25
0.20
2.2
2.3
—
—
—
0
0
95
999
0.94
0.19
3.4
3.3
1.02
1.02
kg/l
0.03
16
134
20
176
1.14
0.17
1.6
1.7
—
—
—
0
0
17
194
0.87
0.17
6.9
12.5
—
—
—
0
0
5
69
0.72
0.17
1.4
1.4
—
—
—
0
0
458
4536
1.05
0.16
4.8
4.4
2.80
2.82
mmol/l
0.24
435
4225
6
78
0.77
0.15
3.5
4.6
—
—
—
0
0
6
79
0.76
0.15
1.2
1.6
—
—
—
0
0
12
102
1.18
0.15
1.3
1.1
—
—
—
0
0
9
82
1.10
0.15
2.8
3.2
3.82
4.09
e9/l
—
9
82
33
304
1.09
0.14
5.9
5.2
0.00
0.11
%
0.82
13
84
10
84
1.19
0.14
2.7
3.6
58.80
56.74
%
—
10
84
20
180
1.12
0.13
2.4
1.8
—
—
—
0
0
11
127
0.86
0.12
1.2
1.4
44.09
192.95
pmol/l
0.92
11
121
10
85
1.18
0.12
1.6
1.2
3.15
2.73
ug/l
—
10
76
450
4468
1.04
0.10
4.2
4.0
4.63
4.71
mmol/l
0.96
428
4182
5
44
1.14
0.10
1.6
1.1
—
—
—
0
0
5
44
1.14
0.10
3.4
4.4
—
—
—
0
0
5
44
1.14
0.10
1.4
1.1
—
—
—
0
0
115
1181
0.97
0.10
4.1
3.5
0.00
0.01
estimate
0.88
43
423
6
54
1.11
0.09
5.0
3.3
0.83
1.13
%
—
6
47
443
4457
0.97
0.08
4.2
3.9
1.50
1.47
mmol/l
0.55
419
4155
7
64
1.09
0.08
1.0
1.3
—
—
nmol/l
—
0
0
7
64
1.09
0.08
1.0
1.2
—
—
—
0
0
40
382
1.05
0.07
4.7
3.9
—
—
—
0
0
24
255
0.94
0.07
2.3
2.4
18.88
55.15
u/ml
1.31
24
243
9
102
0.88
0.06
10.3
4.2
—
—
—
0
0
27
260
1.04
0.03
2.7
3.2
7.44
7.41
ph
—
5
28
113
1118
1.01
0.02
5.0
4.6
1.55
2.61
ug/l
2.01
106
1003
18
172
1.05
0.02
2.9
3.5
24.95
24.84
mmol/l
0.06
18
166
20
196
1.02
0.00
2.7
3.1
—
—
—
0
0
30
299
1.00
0.00
1.5
1.4
—
—
—
0
0
60
601
1.00
0.00
1.5
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
3.37
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
55.57
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
21.5
—
0.42
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
78
0.90
-0.00
1.4
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
4.52
—
0
5
7
78
0.90
-0.00
4.3
12.4
105.29
104.99
mmol/l
—
7
70
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
-0.00
4.3
12.4
10.57
11.01
mmol/l
—
7
70
6
68
0.88
-0.00
1.5
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
9.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
199.00
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
72.66
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
7154.38
—
0
8
0
8
0.00
-0.00
0.0
1.5
—
1.19
—
0
8
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
7.67
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_OTHER_PROTOZOAL and mortality.

Females

Parameter HR [95% CI] p-value
AB1_OTHER_PROTOZOAL 1.862 [1.43, 2.42] < 0.001
Birth year 0.997 [0.99, 1.01] 0.498

During the follow-up period (1.1.1998 — 31.12.2019), 137 out of 1428 females with AB1_OTHER_PROTOZOAL died.

Males

Parameter HR [95% CI] p-value
AB1_OTHER_PROTOZOAL 1.772 [1.39, 2.27] < 0.001
Birth year 0.987 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 128 out of 1146 males with AB1_OTHER_PROTOZOAL died.

Mortality risk

Mortality risk for people of age

years, who have AB1_OTHER_PROTOZOAL.

N-year risk Females Males
1 0.177% 0.302%
5 1.094% 1.879%
10 2.787% 4.981%
15 5.699% 9.485%
20 9.974% 15.868%

Relationships between endpoints

Index endpoint: AB1_OTHER_PROTOZOAL – Other protozoal intestinal diseases

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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