Other and unspecified epidermal thickening

L12_EPIDERMTHICKNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L85.80, L85.81, L85.89, L85.9
  • Hospital discharge: ICD-9 7018G
  • Hospital discharge: ICD-8 70119
  • Cause of death: ICD-10 L85.80, L85.81, L85.89, L85.9
  • Cause of death: ICD-9 7018G
  • Cause of death: ICD-8 70119

2 out of 7 registries used, show all original rules.

1033

4. Check minimum number of events

None

1033

5. Include endpoints

None

1033

6. Filter based on genotype QC (FinnGen only)

991

Control definitions (FinnGen only)

Control exclude
L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7347 3872 3440
Only index persons 6683 3612 3071
Unadjusted period prevalence (%)
Whole population 0.10 0.11 0.10
Only index persons 0.13 0.13 0.12
Median age at first event (years)
Whole population 51.27 51.51 50.95
Only index persons 51.20 51.44 50.92

-FinnGen-

Key figures

All Female Male
Number of individuals 991 548 443
Unadjusted period prevalence (%) 0.20 0.19 0.20
Median age at first event (years) 55.13 51.71 59.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1033
Matched controls
10330
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L85.9
ICD-10 Finland
Epidermal thickening, unspecified
+∞
307.7
370
*
L85.89
ICD-10 Finland
Other specified epidermal thickening
+∞
303.6
276
*
L85.81
ICD-10 Finland
Keratosis pilaris
2738.9
247.0
229
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.9
234.5
296
367
L85.80
ICD-10 Finland
Hudhorn
259.3
173.1
173
8
D05BB02
ATC
acitretin; oral
20.1
158.6
126
71
D07XC01
ATC
betamethasone; topical
6.4
149.4
309
645
D02AE01
ATC
carbamide; topical
8.6
147.7
212
300
E0000UV, ,
ATC
4.8
131.6
681
2955
L84
ICD-10 Finland
Corns and callosities
15.3
130.8
119
87
L30.9
ICD-10 Finland
Dermatitis, unspecified
4.9
128.8
404
1196
TQW80
NOMESCO Finland
Local dermatologic skincare
15.9
118.4
105
73
L85.3
ICD-10 Finland
Xerosis cutis
33.5
107.0
69
22
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
12.7
102.1
103
89
R4180
NOMESCO Finland
Podiatric therapy
24.5
101.5
73
32
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
22.7
81.2
60
28
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
26.5
76.2
53
21
D07AD01
ATC
clobetasol; topical
3.8
72.0
271
874
E000003, ,
ATC
6.6
70.5
121
203
D07AC01
ATC
betamethasone; topical
3.1
68.5
500
2408
L57.0
ICD-10 Finland
Actinic keratosis
4.3
61.9
186
507
B07.9
ICD-10 Finland
Verruca simplex
7.0
58.8
94
146
E000001, ,
ATC
3.0
54.0
311
1282
L40.0
ICD-10 Finland
Psoriasis vulgaris
6.1
52.9
97
173
E000006, ,
ATC
4.7
51.9
131
310
L30.4
ICD-10 Finland
Erythema intertrigo
13.1
51.5
50
40
L04AA06
ATC
mycophenolic acid; systemic
11.4
47.1
50
46
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
8.0
45.8
64
85
B35.3
ICD-10 Finland
Tinea pedis
5.7
45.4
88
165
127
Kela drug reimbursment
Transplant complication
11.7
45.1
47
42
D07AC13
ATC
mometasone; topical
2.6
44.0
378
1885
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.7
43.7
153
460
L04AA01
ATC
[U] ciclosporin
11.5
40.9
43
39
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.2
40.7
185
655
A12AA04
ATC
calcium carbonate; oral
12.2
40.5
41
35
D05AX02
ATC
calcipotriol; topical
5.7
39.8
77
144
D05AX52
ATC
calcipotriol, combinations; topical
4.8
39.8
96
218
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.5
39.5
80
156
D07BC01
ATC
betamethasone and antiseptics; topical
3.2
39.3
178
628
L04AD01
ATC
ciclosporin; systemic
8.6
38.3
50
61
D09AB01
ATC
zinc bandage without supplements; topical
10.4
38.2
43
43
D07AB08
ATC
desonide; topical
3.2
36.9
167
588
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
8.2
36.5
49
62
A46
ICD-10 Finland
Erysipelas
3.0
36.1
192
741
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.9
35.2
191
745
Z94.0
ICD-10 Finland
Kidney transplant status
14.3
34.9
32
23
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.9
34.6
48
63
L04AX01
ATC
azathioprine; systemic
5.0
32.9
74
158
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
7.8
32.0
45
60
XQ848
NOMESCO Finland
Dermatological photography
6.0
31.8
57
99
70119
ICD-8 Finland
Other hypertrophic and atrophic conditions of the skin, Keratosis, hyperkeratosis alia sive NUD
+∞
31.4
30
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.3
30.4
126
419
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.7
29.8
101
295
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.3
28.9
276
1402
S18
ICPC
Laceration/cut
2.1
28.3
508
3296
E000002, ,
ATC
2.8
28.2
157
617
TK800
NOMESCO Finland
Hemodialysis
7.7
28.2
40
54
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
6.5
28.0
46
73
A11CC03
ATC
alfacalcidol; systemic
6.1
28.0
49
83
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.6
27.1
173
729
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
26.9
332
1864
E000004, ,
ATC
6.3
26.9
46
76
C03CA01
ATC
furosemide; systemic
2.2
26.7
328
1837
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
26.6
505
3320
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.8
26.6
144
557
ZXC50
NOMESCO Finland
Cryotherapy
5.6
26.4
51
95
S97
ICPC
Chronic ulcer skin
3.9
26.2
82
226
J01FF01
ATC
clindamycin; systemic
2.2
26.0
309
1707
SPAT1153
SPAT
Removal of sutures
2.1
25.6
353
2061
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
24.5
173
763
H02AB06
ATC
prednisolone; systemic
1.9
23.7
502
3385
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.1
23.5
41
69
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
7.2
23.4
35
50
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
23.2
260
1395
L30.8
ICD-10 Finland
Other specified dermatitis
5.2
23.0
48
96
J01DB01
ATC
cefalexin; oral
2.4
22.6
871
7182
B35.1
ICD-10 Finland
Tinea unguium
3.2
22.6
93
307
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.5
22.5
152
655
D01AE15
ATC
terbinafine; topical
3.1
22.4
97
330
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
6.6
21.5
35
55
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
21.4
332
1998
L89
ICD-10 Finland
Decubitus ulcer and pressure area
24.8
20.9
29
12
D02AX
ATC
Other emollients and protectives
4.5
20.8
52
121
-, ,
ICD-10 Finland
5.1
20.8
44
89
E000007, ,
ATC
3.2
20.6
84
275
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.2
19.9
41
81
D07AA02
ATC
hydrocortisone; topical
2.3
19.9
179
875
D05AX03
ATC
calcitriol; topical
7.9
19.6
27
35
A10AB05
ATC
insulin aspart; parenteral
2.9
19.6
96
350
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
7.5
19.6
28
38
UJF32
NOMESCO Finland
Coloscopy
2.0
19.1
280
1643
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
4.6
18.8
45
101
XQ802
NOMESCO Finland
Epicutan test
3.7
18.8
62
177
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
5.3
18.7
38
74
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.0
18.7
89
319
S20
ICPC
Corn/callosity
5.5
18.6
36
67
TQW99
NOMESCO Finland
Other minor procedure on skin
3.4
18.3
68
210
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
7.3
18.3
27
38
L30.3
ICD-10 Finland
Infective dermatitis
3.8
18.0
55
149
A10AE04
ATC
insulin glargine; parenteral
2.5
17.7
117
497
L20.0
ICD-10 Finland
Besnier prurigo
2.7
17.7
104
417
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
7.5
17.4
25
34
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
17.4
130
584
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
19.0
17.4
26
14
D01BA02
ATC
terbinafine; oral
1.9
17.1
271
1624
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.5
17.1
59
174
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
17.0
127
570
A10AC01
ATC
insulin (human); parenteral
2.7
17.0
95
371
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
16.7
330
2119
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.0
16.6
77
272
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.3
16.6
65
208
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.6
16.6
105
437
L85.1
ICD-10 Finland
Acquired keratosis [keratoderma] palmaris et plantaris
172.7
16.5
17
*
R50.9
ICD-10 Finland
Fever, unspecified
2.1
16.4
173
897
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.3
16.4
33
64
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.0
16.3
208
1156
RJ411, ,
NOMESCO Finland
17.1
16.1
25
15
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
21.3
16.0
23
11
A10AB04
ATC
insulin lispro; parenteral
3.8
16.0
49
133
SPAT1301
SPAT
No procedures
1.8
16.0
331
2149
SPAT1312
SPAT
General health counselling
1.8
15.8
343
2255
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
17.5
15.7
24
14
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.7
15.6
50
140
L82
ICD-10 Finland
Seborrhoeic keratosis
2.1
15.6
171
898
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.4
15.6
39
91
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.1
15.4
43
109
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
15.3
122
563
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.3
15.1
59
188
A07AA09
ATC
vancomycin; oral
6.4
15.1
25
40
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
15.0
196
1096
L40.9
ICD-10 Finland
Psoriasis, unspecified
5.9
15.0
27
47
D01AC02
ATC
miconazole; topical
2.6
14.9
94
390
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
14.8
422
2983
S76
ICPC
Skin infection other
3.0
14.7
65
223
ZZA00
NOMESCO Finland
Split skin graft
4.2
14.7
39
95
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
5.4
14.7
29
55
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
21.4
14.7
21
10
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
14.6
69
246
R06AE07
ATC
cetirizine; oral
1.7
14.6
448
3228
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
14.5
60
198
A10AA01, ,
ATC
4.0
14.5
41
105
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
14.5
403
2826
G47.3
ICD-10 Finland
Sleep apnoea
1.9
14.4
234
1405
J01DA01
ATC
[U] cefalexin
1.7
14.4
620
4873
SPAT1263
SPAT
Sampling
1.7
14.3
432
3093
L20.8
ICD-10 Finland
Other atopic dermatitis
5.8
14.2
26
46
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
14.2
292
1882
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.5
14.1
34
77
137
Kela drug reimbursment
Uraemia requiring dialysis
14.7
14.1
23
16
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
6.8
14.1
22
33
A10AA02, ,
ATC
3.6
14.0
46
131
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
14.0
256
1593
ZXC15
NOMESCO Finland
Use of photodynamic technique
6.1
13.9
24
40
A10AE05
ATC
insulin detemir; parenteral
2.8
13.9
70
259
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
17.8
13.9
21
12
D07CC01
ATC
betamethasone and antibiotics; topical
2.1
13.8
143
733
H02AB09
ATC
hydrocortisone; systemic
4.2
13.8
37
91
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
13.7
410
2919
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
13.4
311
2066
S29
ICPC
Skin symptom/complaint other
1.9
13.4
197
1142
L91.0
ICD-10 Finland
Hypertrophic scar
18.5
13.4
20
11
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
13.4
371
2588
L04AX03
ATC
methotrexate; systemic
2.3
13.3
105
482
SPAT1262
SPAT
Handing over of treatment supplies
1.9
13.3
180
1015
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
13.3
245
1524
J02AC01
ATC
fluconazole; systemic
1.7
13.2
375
2628
N18.8
ICD-10 Finland
Other chronic renal failure
4.4
13.2
33
77
L30.0
ICD-10 Finland
Nummular dermatitis
3.3
13.2
50
157
XQ800
NOMESCO Finland
Prick test
2.5
13.0
88
377
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.1
12.9
55
185
H02AB04
ATC
methylprednisolone; systemic
2.0
12.9
145
767
SPAT1101
SPAT
Orthostatic test
3.2
12.8
51
165
J01CE08
ATC
benzathine benzylpenicillin; parenteral
9.8
12.8
25
26
N02AX02
ATC
tramadol; systemic, rectal
1.6
12.7
417
3026
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
12.7
170
955
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
5.6
12.6
24
44
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
12.6
264
1701
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
12.6
167
935
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
12.5
252
1605
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
12.4
235
1470
ZX120
NOMESCO Finland
Intravenous
2.2
12.4
107
510
D01AE16
ATC
amorolfine; topical
2.1
12.4
122
613
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
12.3
109
525
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.0
12.3
141
750
Z49.1
ICD-10 Finland
Extracorporeal dialysis
9.8
12.3
24
25
R60.0
ICD-10 Finland
Localized oedema
2.1
12.2
124
631
L17
ICPC
Foot/toe symptom/complaint
1.7
12.2
291
1942
WW200
NOMESCO Finland
Immunization
3.9
12.2
35
91
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.6
12.1
39
110
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
18.3
12.1
18
10
L01BA01
ATC
methotrexate; systemic
3.5
12.0
41
120
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
12.0
559
4395
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
4.6
11.9
28
62
E66.01
ICD-10 Finland
Obesity due to excess calories
2.2
11.9
100
471
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.9
11.9
56
200
R06.0
ICD-10 Finland
Dyspnoea
1.7
11.7
265
1739
RJ420, ,
NOMESCO Finland
16.6
11.7
18
11
SPAT1229
SPAT
Assessment of need for aid
2.4
11.7
83
364
D06BB10
ATC
imiquimod; topical
2.7
11.7
63
242
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
12.7
11.7
20
16
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.5
11.6
73
302
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
11.6
103
497
L04AD02
ATC
tacrolimus; systemic
8.7
11.6
24
28
B03XA01
ATC
erythropoietin; parenteral
8.7
11.6
24
28
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
10.2
11.5
22
22
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.1
11.5
49
165
Q82.82
ICD-10 Finland
Inherited keratosis palmaris et plantaris
121.3
11.4
12
*
A10AB01
ATC
insulin (human); parenteral
3.2
11.4
45
145
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.9
11.4
53
188
NH3BG
NOMESCO Finland
MRI of foot
12.0
11.4
20
17
C02AC05
ATC
moxonidine; oral
2.8
11.3
55
200
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
11.3
96
455
L50.3
ICD-10 Finland
Dermatographic urticaria
4.1
11.3
31
78
H03AA01
ATC
levothyroxine sodium; systemic
1.7
11.2
230
1467
C08CA02
ATC
felodipine; oral
2.2
11.2
95
450
SPAT1234
SPAT
Support of social functional capacity
2.7
11.2
60
230
SPAT1147
SPAT
Destruction of skin lesion with external methods
4.4
11.0
27
62
QDB10, ,
SPAT
4.6
11.0
26
58
N05AH04
ATC
quetiapine; oral
1.8
11.0
185
1115
J45.1
ICD-10 Finland
Nonallergic asthma
2.3
10.9
81
363
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.9
10.8
32
85
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
18.0
10.7
16
9
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
10.7
132
719
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
10.7
96
465
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.8
10.6
32
86
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
10.5
191
1176
J45.8
ICD-10 Finland
Mixed asthma
3.4
10.5
37
111
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.2
10.4
94
457
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.5
10.4
35
102
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.0
10.4
29
74
C07AB07
ATC
bisoprolol; oral
1.5
10.3
450
3445
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
10.2
177
1074
J02AC02
ATC
itraconazole; systemic
1.8
10.2
167
996
205
Kela drug reimbursment
Chronic hypertension
1.7
10.2
243
1611
N02BE01
ATC
paracetamol; systemic, rectal
1.8
10.1
886
7941
K92.1
ICD-10 Finland
Melaena
2.5
10.1
63
260
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
11.4
10.1
18
16
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.4
10.1
35
104
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.7
10.1
54
207
T82
ICPC
Obesity
2.9
10.0
48
173
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.1
10.0
27
67
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.4
10.0
66
280
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.2
10.0
40
130
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
40.5
10.0
12
*
C07AB02
ATC
metoprolol; systemic
1.7
10.0
192
1201
C08CA05
ATC
nifedipine; systemic
2.5
9.9
62
257
E66.8
ICD-10 Finland
Other obesity
2.6
9.8
58
233
C03DA01
ATC
spironolactone; oral
2.0
9.8
119
644
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
9.7
9.8
19
20
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
9.8
110
580
J01CF05
ATC
flucloxacillin; systemic
2.4
9.7
68
296
SPAT1325
SPAT
Vaccination
1.6
9.7
329
2370
B03XA02
ATC
darbepoetin alfa; parenteral
4.0
9.6
27
69
B01AC04
ATC
clopidogrel; oral
1.8
9.6
158
943
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
9.5
89
438
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
9.5
40
134
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.3
9.5
69
306
A41.9
ICD-10 Finland
Sepsis, unspecified
2.9
9.5
44
156
C09AA02
ATC
enalapril; systemic
1.7
9.4
177
1098
A05AA02
ATC
ursodeoxycholic acid; oral
4.3
9.4
24
57
N91.1
ICD-10 Finland
Secondary amenorrhoea
4.3
9.4
24
57
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
9.4
66
288
S21
ICPC
Skin texture symptom/complaint
1.8
9.4
138
796
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.2
9.4
82
393
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
9.4
182
1140
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
9.4
80
380
M04AA01
ATC
allopurinol; systemic
1.9
9.3
121
671
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
9.6
9.3
18
19
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
9.3
47
175
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
9.3
108
577
H04AA01
ATC
glucagon; nasal, parenteral
3.5
9.2
31
90
N05BA04
ATC
oxazepam; oral
1.6
9.2
250
1707
L73.8
ICD-10 Finland
Other specified follicular disorders
7.8
9.2
20
26
N03AX12
ATC
[U] gabapentin; oral
1.8
9.1
160
973
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
9.1
198
1278
C09CA01
ATC
losartan; oral
1.6
9.1
232
1560
QDA10
NOMESCO Finland
Incision of skin of lower limb
11.6
9.1
16
14
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
11.6
9.1
16
14
R42
ICD-10 Finland
Dizziness and giddiness
1.7
9.1
210
1378
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.8
9.1
140
820
R03BA02
ATC
budesonide; inhalant
1.7
9.0
178
1120
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.4
9.0
59
250
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
9.0
127
724
A06AD11
ATC
lactulose; oral
1.8
8.9
139
816
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
12.7
8.9
15
12
B05DA
ATC
Isotonic solutions
12.7
8.9
15
12
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.8
8.9
44
162
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
8.8
231
1561
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.2
8.8
73
342
N03AX16
ATC
[U] pregabalin
1.6
8.8
214
1420
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
9.6
8.8
17
18
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
8.8
184
1176
CKC12
NOMESCO Finland
Photocoagulation of retina
2.7
8.7
45
169
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
14.2
8.7
14
10
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.5
8.7
29
84
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.1
8.6
78
379
J01MA14
ATC
moxifloxacin; systemic
2.1
8.6
87
441
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
8.6
88
448
J01FA06
ATC
roxithromycin; oral
1.5
8.6
368
2776
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
8.6
128
741
A02BC02
ATC
pantoprazole; systemic
1.5
8.6
638
5373
SPAT1254
SPAT
Administration of medicine
1.8
8.6
151
919
SPAT1255
SPAT
Intravenous administration of medicine
2.2
8.6
69
320
V03AE02
ATC
sevelamer; oral
16.4
8.6
13
8
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
16.4
8.6
13
8
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
8.5
190
1233
AA1AD
NOMESCO Finland
CT of head and brain
1.6
8.5
247
1711
M05BA04
ATC
alendronic acid; oral
2.1
8.5
76
368
NHQ40
NOMESCO Finland
Amputation of toe
7.4
8.5
19
26
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
8.4
95
501
J01MA02
ATC
ciprofloxacin; systemic
1.5
8.4
352
2639
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.2
8.4
33
106
R03AC02
ATC
salbutamol; inhalant
1.5
8.4
529
4302
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
8.4
242
1671
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
3.2
8.4
32
101
Z49.2
ICD-10 Finland
Other dialysis
12.9
8.4
14
11
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
12.9
8.4
14
11
D06BX02
ATC
ingenol mebutate; topical
4.9
8.4
18
37
L60.0
ICD-10 Finland
Ingrowing nail
2.5
8.4
54
227
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
8.4
406
3138
D06AX01
ATC
fusidic acid; topical
2.0
8.3
95
503
L85.8
ICD-10 Finland
Other specified epidermal thickening
+∞
8.3
8
*
L88
ICD-10 Finland
Pyoderma gangrenosum
+∞
8.3
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
8.3
208
1388
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.2
8.3
33
107
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
8.3
301
2190
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
8.2
258
1816
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
8.2
45
175
C08CA01
ATC
amlodipine; oral
1.5
8.2
335
2499
XCK10
NOMESCO Finland
Photography of fundus of eye
2.0
8.2
94
500
J01AA02
ATC
doxycycline; systemic
1.5
8.1
726
6307
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.0
8.1
96
515
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.4
8.1
28
83
T90
ICPC
Diabetes non-insulin dependent
1.6
8.1
213
1439
XQ845
NOMESCO Finland
Dermatoscopy
4.1
8.1
22
55
377
Kela drug reimbursment
Apremilast and dimethyl fumarate (psoriasis)
17.3
8.1
12
7
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
17.3
8.1
12
7
SPAT1310
SPAT
Counselling related to known health issue
1.5
8.1
302
2209
A07AA02
ATC
nystatin; oral
2.3
8.1
60
269
B35.6
ICD-10 Finland
Tinea inguinalis [Tinea cruris]
3.7
8.0
25
69
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
22.2
8.0
11
5
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.0
346
2607
R06AX22
ATC
ebastine; oral
1.7
8.0
159
1000
SPAT1211
SPAT
Application of soft bandage
2.0
8.0
90
475
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.4
8.0
28
84
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
8.0
135
812
T89
ICPC
Diabetes insulin dependent
2.6
7.9
46
184
SPAT1210
SPAT
Application of cast or individual aid
2.6
7.9
46
184
B05DB
ATC
Hypertonic solutions
13.1
7.9
13
10
NH3CG
NOMESCO Finland
Extensive MRI of foot
8.5
7.8
16
19
AN1
HP
Coronary angiography
1.9
7.8
105
588
I50.0
ICD-10 Finland
Congestive heart failure
2.2
7.8
68
326
A10BA02
ATC
metformin; oral
1.5
7.8
259
1846
SPAT1260
SPAT
Consultation of another employee
1.7
7.8
160
1016
R03BB04
ATC
tiotropium bromide; inhalant
1.9
7.7
102
568
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
15.2
7.7
12
8
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
7.7
63
294
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
7.7
141
867
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
7.7
136
828
V03AE01
ATC
polystyrene sulfonate; oral
6.8
7.6
18
27
V03AE03
ATC
lanthanum carbonate; oral
25.2
7.6
10
*
EBA00
NOMESCO Finland
Extraction of tooth
1.5
7.6
347
2639
K83.0
ICD-10 Finland
Cholangitis
4.1
7.6
20
49
H3603, E103,
ICD-10 Finland
8.9
7.6
15
17
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
7.5
661
5675
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
7.5
214
1471
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.2
7.5
62
291
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
3.7
7.5
23
63
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.9
7.5
21
54
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.5
7.4
25
73
NH3DG
NOMESCO Finland
Very extensive MRI of foot
80.7
7.4
8
*
H3600, E103,
ICD-10 Finland
6.0
7.4
19
32
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.0
7.4
31
104
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.1
7.4
65
313
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.2
7.4
62
293
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.5
7.4
305
2271
A08
ICPC
Swelling
2.3
7.4
54
241
M54.5
ICD-10 Finland
Low back pain
1.5
7.3
334
2536
QBA50
NOMESCO Finland
Cryotherapy of skin of trunk
+∞
7.3
7
*
QCA50
NOMESCO Finland
Cryotherapy of skin of upper limb
+∞
7.3
7
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.6
7.3
199
1355
C09BA02
ATC
enalapril and diuretics; systemic
2.1
7.3
72
363
P01AB01
ATC
metronidazole; oral, rectal
1.5
7.2
362
2795
R03AC03
ATC
terbutaline; inhalant
1.7
7.2
128
779
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
4.3
7.2
18
42
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
7.2
154
987
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
7.2
204
1401
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
30.2
7.2
9
*
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
30.2
7.2
9
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.2
7.2
27
85
L20
ICD-10 Finland
Atopic dermatitis
2.7
7.1
36
134
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.3
7.1
51
225
L04AA32
ATC
apremilast; oral
20.2
7.1
10
5
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
20.2
7.1
10
5
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
7.1
116
689
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
7.1
281
2072
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.9
7.1
94
525
C10AX09
ATC
ezetimibe; oral
1.7
7.1
141
887
SPAT1216
SPAT
Assessment of functional ability
1.7
7.1
145
919
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
10.1
7.0
13
13
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
3.5
7.0
23
66
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
3.5
7.0
23
66
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.6
7.0
38
147
L40.8
ICD-10 Finland
Other psoriasis
7.0
7.0
16
23
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.9
7.0
90
497
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.4
7.0
48
208
J04AB02
ATC
rifampicin; systemic
5.9
6.9
18
31
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
3.1
6.9
28
92
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.1
6.9
28
92
A05
ICPC
Feeling ill
2.0
6.9
72
370
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
13.9
6.9
11
8
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.7
6.9
35
131
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
6.9
100
575
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.8
461
3748
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
6.8
266
1952
B35.4
ICD-10 Finland
Tinea corporis
4.1
6.8
18
44
M48.0
ICD-10 Finland
Spinal stenosis
1.8
6.8
112
668
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.9
6.8
91
510
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
6.8
60
290
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.3
6.8
17
40
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.3
6.8
17
40
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
40.3
6.8
8
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
40.3
6.8
8
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
6.8
95
540
A02BC01
ATC
omeprazole; systemic
1.5
6.8
245
1772
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
2.8
6.8
33
121
196
Kela drug reimbursment
Paricalcitol and cinacalcet
16.8
6.7
10
6
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
16.8
6.7
10
6
H26.4
ICD-10 Finland
After-cataract
1.9
6.7
85
467
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.1
6.7
60
291
S06
ICPC
Rash localized
2.2
6.7
55
258
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
6.7
172
1153
TGC00
NOMESCO Finland
Bronchial lavation
3.0
6.6
29
100
M79.6
ICD-10 Finland
Pain in limb
1.4
6.6
374
2943
C44.72
ICD-10 Finland
Spinocellular carcinoma of the skin of the lower extremity including the hip
12.3
6.6
11
9
TNH31
NOMESCO Finland
Prefabricated orthosis, ankle or foot
4.2
6.6
17
41
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
6.5
92
523
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.9
6.5
87
486
N05AF03
ATC
chlorprothixene; systemic
3.1
6.5
27
90
K29.7
ICD-10 Finland
Gastritis, unspecified
2.6
6.5
37
147
A02BC05
ATC
esomeprazole; systemic
1.4
6.4
361
2834
RJ511, ,
NOMESCO Finland
70.3
6.4
7
*
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
70.3
6.4
7
*
R03DC03
ATC
montelukast; oral
1.6
6.4
151
990
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.0
6.4
27
91
RJ421, ,
NOMESCO Finland
14.4
6.4
10
7
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.8
6.4
90
512
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
6.4
163
1090
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
3.1
6.4
26
86
H36.01
ICD-10 Finland
Diabetic maculopathy
4.1
6.4
17
42
R13
ICD-10 Finland
Dysphagia
2.0
6.4
66
339
S20.2
ICD-10 Finland
Contusion of thorax
2.2
6.3
49
224
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.3
6.3
44
192
CKD40
NOMESCO Finland
Endophotocoagulation of retina
3.6
6.3
20
56
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
11.1
6.3
11
10
8070/3-C44.2
ICD-O-3
Squamous cell carcinoma, NOS, of external ear
18.1
6.3
9
5
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.6
6.3
34
132
N06AX16
ATC
venlafaxine; oral
1.7
6.3
130
826
Q82.80
ICD-10 Finland
Benign familial pemphigus [Hailey-Hailey]
+∞
6.3
6
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
6.3
6
*
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.5
6.2
243
1780
N06AX21
ATC
duloxetine; oral
1.7
6.2
107
646
K10.3
ICD-10 Finland
Alveolitis of jaws
2.3
6.2
47
213
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.2
6.2
48
220
L43.8
ICD-10 Finland
Other lichen planus
4.0
6.2
17
43
C10AA01
ATC
simvastatin; oral
1.4
6.2
360
2841
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.8
6.2
30
110
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
6.2
100
594
R06.5
ICD-10 Finland
Mouth breathing
1.8
6.1
85
481
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
3.8
6.1
18
48
S03
ICPC
Warts
3.1
6.1
25
83
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
3.1
6.1
25
83
J01CA04
ATC
amoxicillin; systemic
1.5
6.1
801
7249
R04.2
ICD-10 Finland
Haemoptysis
2.6
6.1
34
134
C09CA06
ATC
candesartan; oral
1.5
6.1
204
1449
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
8.7
6.1
12
14
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
10.1
6.0
11
11
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.0
6.0
67
353
E66.00
ICD-10 Finland
Metabolic syndrome
2.1
6.0
53
256
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.0
320
2483
SPAT1104
SPAT
Monitoring of emergency patient
2.0
6.0
60
304
104
Kela drug reimbursment
Thyroid insufficiency
2.0
6.0
62
318
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
3.9
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
244
926
3.14
48.35
2.4
1.5
—
—
—
0
0
116
287
4.43
43.28
1.2
1.2
—
—
—
0
0
178
631
3.20
39.01
5.4
3.1
—
—
—
0
0
618
4069
2.29
36.16
9.1
5.7
0.63
0.58
e9/l
0.44
569
3506
619
4081
2.29
36.07
9.1
5.7
0.04
0.04
e9/l
0.63
572
3520
632
4204
2.30
36.02
9.2
5.7
1.93
1.94
e9/l
0.05
590
3721
592
3845
2.26
35.59
9.1
6.1
—
—
—
0
0
684
4761
2.29
34.11
12.3
8.9
4.35
4.07
e9/l
2.61
636
4137
628
4233
2.23
33.73
9.5
5.9
0.20
0.19
e9/l
0.39
584
3704
222
958
2.68
33.61
1.8
1.4
—
—
—
0
0
381
2162
2.21
30.85
5.9
3.7
0.00
0.00
estimate
0.50
94
732
329
1784
2.24
29.58
5.9
3.7
1.02
1.02
kg/l
0.01
36
246
336
1850
2.21
29.00
5.6
3.5
—
—
—
0
0
179
749
2.68
28.47
5.3
4.3
2.13
2.01
mmol/l
0.17
149
609
499
3239
2.05
27.52
5.1
3.2
5.76
5.85
ph
0.23
19
248
512
3384
2.02
26.54
8.1
4.7
35.34
35.73
g/l
0.87
489
3153
176
758
2.59
26.29
5.4
4.2
6.01
5.85
kpa
1.14
171
736
581
4033
2.01
26.00
5.4
3.5
0.03
0.00
estimate
0.69
108
802
579
4029
1.99
25.56
6.7
4.8
0.00
0.00
estimate
-0.00
100
755
582
4075
1.98
25.03
5.4
3.5
0.00
0.00
estimate
-0.00
93
733
94
305
3.29
23.46
7.4
4.4
—
—
—
0
0
151
646
2.57
22.70
4.9
3.8
4.76
4.54
kpa
0.72
146
625
217
1124
2.18
20.96
2.7
1.9
—
—
—
0
0
484
3338
1.85
20.25
3.1
2.3
74.82
76.04
nmol/l
0.41
438
2983
349
2184
1.90
19.73
3.9
3.1
1984.82
1266.23
ng/l
1.19
312
1855
364
2330
1.87
19.04
2.7
2.1
189.02
265.76
u/l
0.90
344
2204
632
4787
1.82
18.93
7.0
4.8
7.09
6.62
mmol/l
4.34
597
4452
138
619
2.42
18.60
3.2
2.6
10.21
10.57
g/l
0.53
126
566
146
674
2.36
18.44
7.2
8.9
—
—
—
0
0
138
637
2.35
17.40
3.0
2.4
5.01
7.44
ug/l
1.61
126
564
779
6396
1.89
16.87
4.9
3.9
14.83
14.73
pmol/l
0.51
735
5803
79
281
2.96
16.83
1.5
1.2
1.38
1.79
u/ml
—
6
16
324
2073
1.82
16.52
3.0
2.2
3.40
2.95
mg/l
2.12
296
1759
752
6129
1.83
16.39
6.2
3.9
13.82
11.78
mm/h
3.09
719
5641
336
2182
1.80
16.26
5.9
4.0
—
—
—
0
0
766
6293
1.84
16.08
11.4
7.1
82.30
78.48
u/l
1.15
736
5903
428
3001
1.73
15.73
5.2
3.5
50.22
58.87
ng/l
0.22
315
2018
194
1065
2.01
15.68
1.5
1.3
569.23
494.53
titre
0.20
39
223
533
3973
1.71
15.60
11.4
6.6
1.20
1.21
mmol/l
4.56
469
3378
372
2514
1.75
15.55
4.1
2.4
56.02
59.60
u/l
0.44
350
2327
218
1251
1.94
15.49
4.2
2.2
11.64
13.50
umol/l
3.82
209
1160
352
2353
1.75
15.23
8.1
3.7
7.40
7.40
ph
0.06
64
435
316
2048
1.78
15.21
4.2
2.6
4730.10
7621.64
umol/l
0.59
289
1800
112
502
2.38
15.04
5.4
5.7
—
—
—
0
0
284
1792
1.81
14.92
2.1
1.7
1.07
1.14
mg/l
0.21
216
1355
498
3676
1.68
14.87
18.3
14.2
1.27
1.26
inr
0.16
158
1083
113
512
2.36
14.80
1.4
1.2
254.00
266.47
u/ml
0.05
105
467
187
1034
1.99
14.75
14.2
5.3
1.09
1.05
mmol/l
1.40
182
944
493
3637
1.68
14.70
10.2
5.9
1.20
1.21
mmol/l
4.82
468
3307
149
760
2.12
14.63
2.0
2.1
359.72
375.50
nmol/l
0.36
135
701
217
1272
1.89
14.37
6.2
3.7
0.81
0.82
mmol/l
0.36
202
1199
352
2395
1.71
14.06
4.7
3.7
18.33
9.48
mg/mmol
0.92
253
1504
550
4213
1.65
13.88
8.8
6.1
10.69
11.52
umol/l
1.38
531
3999
444
3224
1.66
13.80
2.5
2.0
—
—
—
0
0
364
2513
1.69
13.70
4.0
3.1
7.18
7.72
mmol/l
1.60
317
2128
198
1147
1.90
13.53
4.2
2.2
2.28
2.36
g/l
1.12
189
1061
187
1065
1.92
13.44
4.2
2.3
21.63
23.42
%
1.04
167
906
335
2274
1.70
13.36
4.2
3.2
78.87
284.46
mg/l
1.92
247
1452
306
2037
1.71
13.07
8.2
6.7
—
—
—
0
0
122
603
2.16
12.94
6.3
3.8
123.71
81.66
ng/l
2.80
112
534
488
3683
1.62
12.65
3.9
2.7
124.74
120.45
ug/l
0.17
466
3386
668
5452
1.64
12.46
5.8
4.2
69.80
2966.92
e6/l
—
10
84
98
454
2.28
12.16
1.5
1.2
—
—
—
0
0
874
7698
1.88
12.04
5.9
4.6
1.91
1.90
mu/l
0.11
824
7047
262
1708
1.72
11.92
3.6
2.4
6.25
5.77
e6/l
0.16
242
1537
928
8348
2.10
11.90
24.1
13.1
22.19
24.26
mg/l
1.29
795
6546
137
730
2.01
11.87
3.5
2.4
0.22
0.21
g/l
0.15
127
682
160
910
1.90
11.45
4.0
2.7
1.80
1.78
%
0.13
147
816
127
669
2.02
11.35
2.5
2.6
72.45
71.13
e9/l
0.17
111
520
377
2728
1.60
11.28
3.7
3.2
2.34
2.35
mmol/l
0.82
342
2410
100
489
2.16
10.87
1.8
1.7
0.99
1.38
g/l
2.65
92
450
228
1463
1.72
10.87
1.9
1.7
1356.61
1175.49
nmol/l
1.76
195
1109
431
3256
1.56
10.51
2.1
1.9
91.89
94.47
pmol/l
0.59
258
1695
255
1702
1.66
10.44
1.7
1.7
450.18
32702180.71
pmol/l
1.92
215
1425
480
3725
1.54
10.30
9.6
5.8
0.66
0.66
%
0.04
461
3476
493
3857
1.53
10.14
9.6
5.8
2.66
2.85
%
1.35
472
3605
681
5718
1.56
10.09
6.1
4.1
—
—
—
0
0
495
3881
1.53
10.05
10.0
6.0
8.39
8.55
%
0.59
473
3639
843
7460
1.71
9.95
7.7
5.4
41.63
39.49
mmol/mol
6.26
791
6905
149
868
1.84
9.83
6.7
8.4
1.46
1.27
mmol/l
0.27
121
686
316
2257
1.58
9.70
4.0
3.0
0.29
0.48
e6/l
1.68
262
1726
49
182
2.78
9.69
2.3
2.4
211.88
97.42
ug/min
0.82
29
113
505
3998
1.51
9.66
9.7
5.8
27.30
28.21
%
1.00
484
3755
497
3940
1.50
9.33
9.4
5.6
58.10
56.91
%
1.39
478
3697
211
1379
1.67
9.26
3.2
2.7
1.74
1.12
e6/l
0.62
144
798
212
1391
1.66
9.15
1.3
1.3
32.80
32.12
iu/ml
0.03
74
448
221
1474
1.64
8.93
3.0
3.0
2.44
2.44
mmol/l
0.07
201
1288
468
3687
1.49
8.93
13.1
9.0
0.00
0.00
e9/l
0.02
416
2981
117
653
1.89
8.80
4.4
4.0
0.73
0.94
%
0.50
53
228
383
2903
1.51
8.78
4.8
3.6
44.75
113.36
e6/l
1.61
292
2058
334
2478
1.51
8.41
3.7
2.9
—
—
—
0
0
102
559
1.92
8.11
6.0
3.8
5.20
5.15
kpa
0.20
95
538
927
8545
1.83
8.00
26.3
15.0
139.41
139.63
mmol/l
1.84
914
8304
186
1219
1.64
7.99
3.3
2.1
29.47
29.68
s
0.21
181
1184
41
154
2.73
7.98
6.3
4.1
—
—
—
0
0
665
5692
1.47
7.90
5.2
3.6
—
—
—
0
0
928
8565
1.82
7.86
26.5
15.1
4.00
3.97
mmol/l
3.34
914
8303
235
1639
1.56
7.77
2.1
1.9
—
—
—
0
0
300
2207
1.51
7.75
3.9
3.0
—
—
—
0
0
77
389
2.06
7.71
2.6
2.3
—
—
—
0
0
100
555
1.89
7.65
6.1
3.8
7.42
7.41
ph
0.20
13
53
353
2690
1.47
7.65
5.0
3.2
38.27
31.92
u/l
0.73
342
2555
156
993
1.67
7.48
2.3
1.5
—
—
—
0
0
268
1945
1.51
7.33
1.4
1.3
1.43
1.51
u/ml
0.06
81
499
34
121
2.87
7.32
2.2
1.4
—
—
—
0
0
38
144
2.70
7.29
3.5
2.7
—
—
—
0
0
107
617
1.82
7.26
4.5
4.1
0.14
0.11
%
0.19
44
192
104
599
1.82
7.09
4.2
3.8
0.31
0.63
%
1.49
42
197
41
166
2.53
6.91
6.7
4.4
2.48
2.46
mmol/l
0.01
36
118
195
1340
1.56
6.81
1.3
1.3
6.14
12.20
u/ml
1.00
75
511
262
1921
1.49
6.75
1.6
1.5
18.76
20.82
nmol/l
1.31
232
1626
101
587
1.80
6.68
4.5
4.1
0.03
0.12
%
0.85
38
160
947
8875
1.81
6.49
16.3
9.7
26.48
26.11
u/l
0.30
926
8552
323
2485
1.44
6.44
4.5
3.1
30.68
86.03
e6/l
1.32
265
1931
472
3885
1.40
6.38
2.9
2.5
—
—
—
0
0
236
1712
1.49
6.37
1.8
1.4
2.31
2.35
g/l
0.14
161
1046
870
7995
1.56
6.27
5.7
4.3
6.14
5.89
mmol/l
4.75
811
7287
50
232
2.21
6.25
5.5
3.8
8.48
8.55
kpa
0.11
44
225
939
8798
1.74
6.17
22.3
12.3
—
—
—
0
0
67
350
1.98
6.16
1.3
2.2
1.55
1.51
g/l
0.14
59
312
851
7798
1.52
6.05
5.2
3.8
1.40
1.28
mmol/l
4.58
791
7153
634
5514
1.39
5.98
4.6
3.1
57.98
47.23
u/l
1.82
588
5162
20
59
3.44
5.88
1.9
2.3
930.67
465.41
e6/l
0.46
15
46
65
342
1.96
5.86
2.6
2.3
3723.48
4063.61
u/l
0.04
22
140
14
23
6.15
5.70
1.0
1.0
—
—
—
0
0
891
8273
1.56
5.67
5.9
4.7
2.66
2.76
mmol/l
2.40
828
7638
27
98
2.80
5.66
1.0
1.1
1.57
1.51
g/l
0.24
27
88
151
1024
1.56
5.55
3.0
2.3
113.51
119.94
ug/g
0.12
121
809
86
506
1.76
5.48
1.8
2.6
—
—
—
0
0
23
78
2.99
5.44
1.3
1.3
0.35
0.40
g/l
0.27
16
55
23
78
2.99
5.44
1.3
1.3
5.73
7.56
g/l
1.41
15
56
23
78
2.99
5.44
1.3
1.3
2.38
2.75
g/l
0.73
15
55
38
167
2.32
5.43
1.7
1.4
266.10
234.64
u/ml
0.29
20
99
35
149
2.40
5.36
3.4
2.4
15.52
16.41
%
0.53
19
72
99
617
1.67
5.14
2.7
3.0
65.21
66.95
g/l
1.53
93
568
23
81
2.88
5.11
1.3
1.3
—
—
—
0
0
92
565
1.69
5.05
1.9
1.4
—
—
—
0
0
82
489
1.74
5.01
6.6
8.5
24.85
24.98
mmol/l
0.11
82
484
870
8095
1.47
4.88
5.4
4.2
1.39
1.46
mmol/l
6.03
815
7478
15
33
4.60
4.87
1.1
1.1
1790.53
1825.64
miu/ml
0.04
15
33
254
1959
1.39
4.79
2.5
2.2
—
—
—
0
0
785
7187
1.38
4.69
31.2
17.1
332.07
332.79
g/l
1.42
778
7131
34
153
2.26
4.64
1.9
1.5
136.89
99.19
u/ml
—
9
26
99
635
1.62
4.61
3.6
2.8
190.48
188.04
ng/l
0.02
92
582
980
9394
1.84
4.60
34.9
19.4
40.13
40.20
%
0.13
929
8770
28
116
2.45
4.58
2.7
2.7
—
—
—
0
0
981
9408
1.85
4.58
35.1
19.4
134.50
135.46
g/l
1.19
974
9255
25
98
2.59
4.57
1.4
1.7
—
—
—
0
0
980
9398
1.83
4.54
34.9
19.3
253.43
250.11
e9/l
0.80
968
9147
980
9402
1.83
4.47
34.7
19.2
30.16
30.24
pg
0.68
973
9252
980
9402
1.83
4.47
34.7
19.2
90.76
90.72
fl
0.09
973
9254
12
23
5.27
4.46
1.1
1.1
—
—
—
0
0
12
23
5.27
4.46
4.2
2.3
—
—
—
0
0
54
294
1.88
4.46
1.6
1.3
—
—
—
0
0
980
9403
1.82
4.45
34.9
19.3
4.49
4.51
e12/l
0.47
963
9131
872
8151
1.45
4.45
5.8
4.2
4.50
4.65
mmol/l
4.31
821
7571
58
324
1.84
4.43
4.7
6.6
0.87
0.91
%
0.45
58
305
219
1670
1.40
4.38
4.3
2.8
513.37
555.47
mosm/kgh2o
2.25
196
1437
43
219
2.01
4.31
1.4
1.5
228.74
292.02
ug/g
1.09
25
127
11
20
5.55
4.29
5.6
4.7
—
—
—
0
0
979
9401
1.79
4.29
35.0
19.3
7.01
6.71
e9/l
2.71
964
9125
19
67
2.87
4.24
2.5
2.6
38.28
37.52
%
0.07
19
67
13
30
4.38
4.13
2.6
1.5
—
—
—
0
0
57
328
1.78
3.98
4.7
6.5
1.98
1.58
%
1.43
57
308
316
2587
1.32
3.95
2.7
2.3
—
—
—
0
0
180
1352
1.40
3.92
2.0
1.6
—
—
—
0
0
9
15
6.04
3.82
1.2
1.3
—
—
—
0
0
14
38
3.72
3.80
1.1
1.1
110.07
622.66
u/l
1.03
14
32
34
167
2.07
3.79
2.7
2.2
125.09
129.90
g/l
0.38
23
123
40
210
1.94
3.72
1.2
1.3
48.33
97.50
titre
—
6
16
39
203
1.96
3.72
1.5
1.2
7.72
2.50
u/ml
—
6
19
45
247
1.86
3.67
1.3
1.1
—
—
—
0
0
284
2312
1.31
3.65
4.6
3.7
—
—
—
0
0
16
56
2.89
3.64
2.6
2.7
35.77
39.60
%
—
9
29
130
934
1.45
3.62
4.6
2.8
8.71
8.11
umol/l
0.13
113
805
76
487
1.61
3.59
1.4
1.3
39.92
45.99
au/ml
—
8
32
34
171
2.02
3.57
1.9
1.5
—
—
—
0
0
27
126
2.17
3.44
1.6
1.5
0.22
0.38
nmol/l
1.45
22
100
10
22
4.58
3.43
2.2
2.4
—
—
—
0
0
33
170
1.97
3.27
1.6
1.2
46.36
49.84
u/ml
—
5
10
138
1023
1.40
3.24
1.3
1.3
—
—
—
0
0
39
214
1.85
3.22
1.7
1.5
492.54
489.90
mg/l
0.02
39
201
82
550
1.53
3.21
2.7
2.4
12.26
23.03
au/ml
—
5
40
788
7355
1.30
3.20
24.2
16.0
14.77
14.79
%
0.03
778
7220
20
85
2.38
3.16
1.2
1.2
—
—
—
0
0
27
131
2.09
3.14
1.3
1.7
0.49
0.86
g/l
1.10
19
102
35
188
1.89
3.09
1.9
1.7
11.21
30.19
e6/l
0.54
29
155
35
188
1.89
3.09
1.9
1.8
81.93
698.97
e6/l
0.57
30
158
44
255
1.76
3.06
15.4
10.1
—
—
—
0
0
49
293
1.71
3.05
3.9
2.4
23.65
21.33
s
1.14
43
264
23
106
2.20
3.04
3.8
2.6
—
—
—
0
0
22
100
2.23
3.01
1.5
1.5
—
—
—
0
0
26
127
2.07
2.99
10.1
3.2
—
—
—
0
0
66
429
1.58
2.98
7.0
3.8
—
—
—
0
0
5
5
10.04
2.98
1.8
1.0
—
—
—
0
0
91
638
1.47
2.90
10.1
3.4
1.21
1.23
mmol/l
1.20
81
539
44
260
1.72
2.87
1.5
1.4
11.71
8.16
u/l
0.60
35
206
28
144
1.97
2.82
1.1
1.1
—
13.23
—
0
10
30
538
0.54
2.81
1.6
1.4
—
—
—
0
0
146
1122
1.35
2.76
1.3
1.2
—
—
—
0
0
20
91
2.22
2.75
2.3
2.5
—
—
—
0
0
18
79
2.30
2.68
2.3
2.4
1.38
1.64
g/24h
—
6
40
21
100
2.12
2.60
1.0
1.2
—
—
—
0
0
32
178
1.82
2.58
1.4
2.0
0.78
0.81
nmol/l
0.10
25
153
12
44
2.75
2.55
1.3
1.2
146.17
140.07
nmol/l
0.09
12
44
17
75
2.29
2.52
2.4
2.7
17.56
24.58
nmol/l
2.34
17
68
247
2063
1.26
2.51
5.8
3.8
89.91
90.36
%
0.10
238
2008
11
37
2.99
2.49
3.1
2.7
552.55
1047.03
u/ml
0.78
11
37
14
57
2.48
2.45
1.4
1.5
—
—
—
0
0
31
174
1.81
2.44
6.3
9.9
12.35
11.31
mmol/l
0.79
31
158
18
83
2.19
2.42
1.8
2.2
—
—
—
0
0
31
175
1.80
2.40
6.3
9.9
103.06
105.70
mmol/l
1.27
31
159
266
2256
1.24
2.35
4.3
3.1
—
—
—
0
0
21
105
2.02
2.32
3.4
2.3
—
—
—
0
0
10
34
2.96
2.28
2.3
1.9
130.00
67.18
ug/l
—
10
34
48
311
1.57
2.26
4.8
3.8
0.22
0.28
g/l
0.30
27
130
32
187
1.73
2.23
1.7
1.8
7410.19
15886.93
e6/l
1.25
27
139
29
166
1.77
2.17
1.9
1.8
—
—
—
0
0
14
61
2.31
2.15
1.4
2.5
5.80
2.57
u/field
—
5
28
122
950
1.32
2.14
1.5
1.7
—
—
—
0
0
13
55
2.38
2.12
1.2
1.0
—
—
—
0
0
25
138
1.83
2.10
3.0
4.3
71.08
62.23
%
1.13
25
138
8
25
3.22
2.09
3.3
1.9
—
—
—
0
0
95
715
1.36
2.09
5.1
3.5
—
—
—
0
0
118
920
1.32
2.06
1.9
1.7
—
—
—
0
0
23
125
1.86
2.03
1.6
1.6
—
—
—
0
0
12
50
2.42
2.03
1.5
1.2
—
—
—
0
0
85
632
1.38
2.02
1.6
1.4
—
—
—
0
0
182
1505
1.25
2.01
4.4
3.7
416.13
547.04
ng/l
0.21
134
1126
10
39
2.58
1.94
1.3
1.3
—
—
—
0
0
58
811
0.70
1.93
1.3
1.4
—
—
—
0
0
68
491
1.41
1.93
3.2
3.3
4.42
4.59
pmol/l
0.74
62
435
13
60
2.18
1.78
1.7
1.3
51.01
32.43
mmol/l
0.99
13
55
74
552
1.37
1.75
2.9
2.8
7.14
6.55
e9/l
0.08
63
462
37
241
1.56
1.75
4.3
3.3
—
—
—
0
0
28
442
0.62
1.70
1.2
1.6
—
—
—
0
0
249
2167
1.20
1.67
2.1
1.6
1.56
1.37
mmol/l
2.21
204
1825
50
352
1.44
1.66
2.3
1.8
—
—
—
0
0
7
25
2.81
1.65
4.7
4.5
57.93
50.36
%
—
7
25
7
25
2.81
1.65
4.4
4.4
—
34.83
—
0
6
263
2983
0.84
1.65
3.5
2.7
—
—
—
0
0
15
77
1.96
1.59
1.5
1.9
—
—
—
0
0
41
281
1.48
1.56
1.2
1.3
181.64
269.52
miu/ml
0.67
16
136
88
688
1.31
1.55
1.5
1.4
—
—
—
0
0
112
906
1.26
1.52
1.4
1.3
—
—
—
0
0
10
45
2.23
1.46
1.1
1.2
—
—
—
0
0
9
38
2.38
1.46
1.8
1.7
0.97
1.22
nmol/l
—
9
29
15
80
1.89
1.45
7.8
3.2
—
—
—
0
0
5
16
3.13
1.44
1.0
1.2
—
—
—
0
0
5
16
3.13
1.44
2.6
1.9
—
—
—
0
0
55
407
1.37
1.41
8.7
11.8
—
—
—
0
0
24
150
1.61
1.39
3.3
3.7
126.18
765.91
u/ml
0.68
24
143
22
135
1.64
1.36
1.0
1.1
—
—
—
0
0
27
175
1.56
1.35
2.5
3.9
—
—
—
0
0
19
113
1.69
1.32
2.3
1.7
—
—
—
0
0
20
121
1.67
1.31
1.2
1.0
—
—
—
0
0
16
91
1.77
1.29
1.5
1.2
—
—
—
0
0
5
18
2.79
1.28
1.6
1.1
—
—
—
0
0
67
520
1.31
1.28
3.2
2.7
—
—
—
0
0
8
158
0.50
1.25
1.5
1.2
—
—
—
0
0
11
201
0.54
1.22
1.5
1.5
—
—
—
0
0
20
124
1.63
1.21
1.3
1.2
—
—
—
0
0
6
26
2.32
1.19
1.0
1.5
—
—
—
0
0
6
26
2.32
1.19
1.7
1.4
64.83
97.04
nmol/24h
—
6
26
8
39
2.06
1.15
1.1
1.0
—
—
—
0
0
13
72
1.82
1.15
1.3
1.1
—
—
—
0
0
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
33
233
1.43
1.14
1.3
1.8
44.06
40.13
nmol/l
0.38
33
221
11
196
0.56
1.13
1.4
1.4
—
—
—
0
0
49
371
1.34
1.13
1.4
1.4
27.93
25.63
iu/l
0.18
43
307
11
195
0.56
1.11
1.4
1.4
—
—
—
0
0
129
1503
0.84
1.10
3.1
3.1
0.71
0.76
ug/l
0.36
87
979
11
59
1.87
1.07
10.1
3.5
—
—
—
0
0
52
402
1.31
1.05
7.3
10.4
24.35
24.53
mmol/l
0.16
52
390
52
402
1.31
1.05
5.9
3.5
—
—
—
0
0
106
892
1.21
1.05
1.4
1.4
—
—
—
0
0
15
90
1.68
1.04
2.7
2.1
—
—
—
0
0
22
146
1.52
1.04
1.1
1.0
1.69
1.35
u/ml
0.20
13
78
7
35
2.01
1.00
4.7
2.1
28.71
31.29
umol/l
—
7
35
14
84
1.68
0.98
1.1
1.0
—
—
—
0
0
10
54
1.86
0.96
1.0
1.1
304.60
285.15
mg/l
—
10
47
13
77
1.70
0.95
1.6
1.5
284.31
284.05
mosm/kgh2o
0.01
13
59
20
133
1.51
0.95
1.2
1.5
—
—
—
0
0
11
62
1.78
0.94
1.6
1.5
—
—
—
0
0
30
217
1.39
0.94
7.0
4.4
—
—
—
0
0
45
348
1.31
0.93
1.7
1.6
—
—
—
0
0
9
52
1.74
0.92
3.7
1.8
—
—
—
0
0
8
42
1.91
0.88
1.1
1.0
—
—
—
0
0
10
56
1.79
0.88
1.0
1.1
—
—
—
0
0
8
43
1.87
0.87
1.1
1.5
—
—
—
0
0
23
161
1.44
0.87
2.0
2.0
—
—
—
0
0
18
121
1.50
0.83
1.1
1.0
6.70
4.17
u/ml
0.29
11
58
8
46
1.74
0.82
2.0
3.0
—
—
—
0
0
11
65
1.70
0.82
1.5
1.1
—
—
—
0
0
24
173
1.40
0.79
1.2
1.2
—
—
—
0
0
9
149
0.60
0.79
2.8
1.7
—
—
—
0
0
6
34
1.77
0.76
1.2
1.3
—
—
—
0
0
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
7
38
1.85
0.73
2.1
3.3
—
—
—
0
0
7
38
1.85
0.73
2.3
2.2
56.41
42.81
umol/l
—
7
29
5
25
2.00
0.72
2.8
1.3
—
—
—
0
0
5
25
2.00
0.72
1.0
1.7
—
—
—
0
0
13
84
1.55
0.72
1.4
1.1
—
—
—
0
0
7
40
1.76
0.71
1.9
2.9
35208.14
44747.50
ug/l
—
7
40
7
40
1.76
0.71
1.0
1.4
184.86
173.27
mmol/24h
—
7
40
10
61
1.65
0.68
2.9
6.5
12.15
11.08
%
—
10
61
30
231
1.31
0.68
1.1
1.2
—
—
—
0
0
23
170
1.36
0.68
1.4
1.3
—
—
—
0
0
92
803
1.16
0.66
3.2
4.3
11.56
28.09
ug/l
0.77
72
659
19
137
1.39
0.65
1.4
1.2
—
—
—
0
0
20
146
1.38
0.64
1.2
1.1
3.43
6.76
u/ml
0.58
14
82
93
815
1.16
0.64
1.7
1.4
—
—
—
0
0
46
378
1.23
0.64
1.7
1.6
—
—
—
0
0
30
234
1.29
0.63
2.4
3.8
48.60
78.34
mg/l
0.56
24
197
12
79
1.53
0.62
1.6
1.4
—
—
—
0
0
38
307
1.25
0.61
3.2
3.6
5932.78
1324.43
u/ml
0.36
33
265
36
289
1.25
0.61
1.6
1.7
—
—
—
0
0
46
380
1.22
0.61
1.7
1.6
—
—
—
0
0
146
1324
1.12
0.60
3.9
2.9
4.58
2.62
e6/l
0.43
83
744
23
174
1.33
0.60
3.2
4.4
—
—
—
0
0
23
174
1.33
0.60
1.2
1.8
—
—
—
0
0
15
105
1.43
0.60
1.1
1.0
9.07
4.04
u/ml
—
8
41
12
80
1.51
0.60
1.0
1.1
—
—
—
0
0
12
80
1.51
0.60
1.4
1.6
—
—
—
0
0
69
595
1.17
0.59
1.1
1.2
124.03
145.94
iu/ml
0.14
19
238
46
383
1.21
0.58
1.7
1.6
—
—
—
0
0
8
55
1.46
0.56
2.3
1.5
76.13
81.71
umol/l
—
8
55
62
533
1.17
0.56
1.1
1.2
—
—
—
0
0
6
37
1.63
0.55
1.3
1.5
5.28
6.27
mmol/l
—
6
37
32
258
1.25
0.54
1.9
2.2
—
—
—
0
0
73
638
1.16
0.54
2.2
2.1
13.50
12.73
nmol/l
0.31
65
562
45
377
1.20
0.54
1.7
1.5
—
—
—
0
0
275
2590
1.08
0.54
4.4
5.0
4.67
2.95
ug/l
0.27
250
2308
6
96
0.62
0.52
1.3
1.9
13.38
13.16
%
—
6
96
14
100
1.41
0.52
1.5
1.8
—
—
—
0
0
18
135
1.34
0.51
1.9
1.2
—
—
—
0
0
14
191
0.73
0.51
1.1
1.3
—
—
—
0
0
9
65
1.39
0.50
1.3
1.2
—
—
—
0
0
9
65
1.39
0.50
1.9
1.6
0.91
1.02
g/l
—
9
65
29
235
1.24
0.48
2.4
3.8
31.96
93.10
mg/l
0.64
23
198
12
85
1.42
0.47
5.3
3.8
—
—
—
0
0
25
200
1.26
0.46
1.5
1.2
—
—
—
0
0
40
339
1.19
0.44
1.1
1.1
—
—
—
0
0
10
69
1.45
0.44
1.1
1.3
—
—
—
0
0
10
140
0.71
0.43
1.1
1.1
—
—
—
0
0
10
139
0.72
0.42
1.1
1.1
—
—
—
0
0
5
33
1.52
0.41
14.6
11.5
—
—
—
0
0
26
213
1.23
0.41
2.1
1.8
2.30
5.13
iu/l
—
10
75
0
17
0.00
0.40
0.0
7.6
—
—
—
0
0
36
306
1.18
0.40
1.8
1.7
—
—
—
0
0
5
37
1.35
0.37
2.2
1.6
—
—
—
0
0
21
171
1.23
0.36
1.2
1.1
1.29
2.35
u/ml
0.51
12
96
6
43
1.40
0.35
1.5
1.7
—
—
—
0
0
30
351
0.85
0.34
1.1
1.1
—
—
—
0
0
6
46
1.31
0.33
1.5
1.3
—
—
—
0
0
6
47
1.28
0.32
1.7
1.6
8.33
9.78
mmol/l
—
6
47
18
146
1.24
0.32
1.2
1.1
1.41
1.23
u/ml
—
8
70
250
2394
1.06
0.32
1.3
1.5
—
—
—
0
0
7
56
1.25
0.29
1.0
1.4
121.20
183.09
pmol/l
—
7
56
33
288
1.15
0.29
2.8
2.7
—
—
—
0
0
20
167
1.20
0.28
1.3
1.8
195.90
211.37
pmol/l
0.18
20
158
22
186
1.19
0.28
6.1
3.4
31.91
27.47
mg/l
0.21
16
108
81
750
1.09
0.27
3.1
2.2
33.69
33.63
u/l
0.00
72
637
9
73
1.23
0.25
1.0
1.2
—
—
—
0
0
9
75
1.20
0.25
1.4
1.4
6.74
6.99
mmol/l
—
9
69
6
82
0.73
0.24
3.0
2.5
—
—
—
0
0
72
670
1.08
0.23
1.2
1.2
—
—
—
0
0
14
116
1.21
0.22
1.7
1.2
2.63
5.73
u/ml
—
8
49
0
11
0.00
0.21
0.0
3.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.92
—
0
7
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
17
197
0.86
0.19
1.1
1.1
—
—
—
0
0
7
58
1.21
0.18
3.3
2.1
3.16
2.21
ug/l
—
7
47
11
91
1.21
0.17
1.6
2.0
—
—
—
0
0
7
89
0.79
0.14
1.3
1.1
—
—
—
0
0
7
90
0.78
0.14
1.0
1.3
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
10
108
0.93
0.03
1.1
1.3
0.53
0.59
nmol/l
—
10
103
14
132
1.06
0.02
1.6
1.7
—
—
—
0
0
10
102
0.98
0.00
1.1
1.3
—
—
—
0
0
77
772
1.00
0.00
6.2
3.8
—
—
—
0
0
10
99
1.01
0.00
1.1
1.3
—
—
nmol/l
—
0
0
20
205
0.98
0.00
3.2
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
15.89
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.74
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
188.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
142.40
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
4.52
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
3.0
2.2
414.20
490.27
min
—
5
33

Mortality – FinRegistry

Association

Association between endpoint L12_EPIDERMTHICKNAS and mortality.

Females

Parameter HR [95% CI] p-value
L12_EPIDERMTHICKNAS 1.228 [1.06, 1.42] 0.007
Birth year 0.994 [0.99, 1.0] 0.146

During the follow-up period (1.1.1998 — 31.12.2019), 517 out of 3191 females with L12_EPIDERMTHICKNAS died.

Males

Parameter HR [95% CI] p-value
L12_EPIDERMTHICKNAS 1.233 [1.05, 1.44] 0.009
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 555 out of 2752 males with L12_EPIDERMTHICKNAS died.

Mortality risk

Mortality risk for people of age

years, who have L12_EPIDERMTHICKNAS.

N-year risk Females Males
1 0.112% 0.254%
5 0.796% 1.429%
10 1.809% 3.74%
15 3.451% 7.347%
20 6.151% 12.246%

Relationships between endpoints

Index endpoint: L12_EPIDERMTHICKNAS – Other and unspecified epidermal thickening

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data