No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
111 |
4. Check minimum number of eventsNone |
111 |
5. Include endpointsNone |
111 |
6. Filter based on genotype QC (FinnGen only) |
106 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Epileptic seizures related to drugs
based on the number of shared cases.
Similar with more cases:
- Epilepsy
- Episodal and paroxysmal disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 693 | 270 | 422 |
| Only index persons | 667 | 264 | 403 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 34.78 | 37.41 | 33.12 |
| Only index persons | 34.73 | 37.19 | 33.12 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 106 | 47 | 59 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 40.17 | 41.74 | 38.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 111
- Matched controls
- 1110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G40.52
ICD-10 Finland
Epileptic seizures related to drugs
+∞
160.1
111
*
N05AH02
ATC
clozapine; systemic
83.9
117.7
71
23
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
62.0
110.5
84
53
R56.8
ICD-10 Finland
Other and unspecified convulsions
61.5
105.9
70
30
N03AG01
ATC
valproic acid; systemic, rectal
44.5
93.3
70
41
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
54.6
81.8
51
17
N05AH03
ATC
olanzapine; systemic
31.5
78.6
69
55
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
36.9
71.4
51
25
N05AA02
ATC
levomepromazine; systemic
36.3
66.7
47
22
T36
ICD-10 Finland
Poisoning by systemic antibiotics
31.7
65.1
49
27
N05AX08
ATC
risperidone; systemic
22.6
61.6
59
53
F29
ICD-10 Finland
Unspecified nonorganic psychosis
25.1
61.5
53
39
F20.9
ICD-10 Finland
Schizophrenia, unspecified
34.5
60.8
43
20
N05AX12
ATC
aripiprazole; systemic
24.6
59.4
51
37
N05BA06
ATC
lorazepam; systemic, sublingual
29.7
58.3
44
24
N03AX09
ATC
lamotrigine; oral
24.9
57.3
48
33
N05BA01
ATC
diazepam; systemic, rectal
15.0
47.1
59
78
N05AH04
ATC
quetiapine; oral
15.1
46.5
79
156
N05CD07
ATC
temazepam; oral
19.9
46.2
42
33
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
22.9
41.9
34
21
AA1AD
NOMESCO Finland
CT of head and brain
10.5
35.8
63
123
G40.9
ICD-10 Finland
Epilepsy, unspecified
47.1
31.7
38
12
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
11.8
30.6
38
47
N04AA02
ATC
biperiden; systemic
77.1
30.1
33
6
N05AF03
ATC
chlorprothixene; systemic
43.6
29.5
36
12
N06AB04
ATC
citalopram; systemic
8.8
29.3
55
112
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
40.2
29.0
36
13
N05BA04
ATC
oxazepam; oral
8.4
28.8
68
176
N06AB06
ATC
sertraline; oral
8.7
26.5
45
81
N03AE01
ATC
clonazepam; systemic
13.5
26.5
28
27
P72
ICPC
Schizophrenia
28.7
24.4
33
16
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
10.1
23.9
32
43
A06AD11
ATC
lactulose; oral
9.2
21.6
31
45
N05AB03
ATC
perphenazine; systemic, rectal
19.9
21.1
32
22
C07AA05
ATC
propranolol; systemic
6.0
19.9
56
161
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.2
19.8
37
72
N05BA12
ATC
alprazolam; oral
7.9
19.5
32
54
N05AD01
ATC
haloperidol; systemic
47.7
19.4
23
6
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
8.2
19.1
30
48
P29
ICPC
Psychological sympt/compl other
7.4
18.7
33
60
N05CF01
ATC
zopiclone; oral
5.5
18.1
59
190
N06AX16
ATC
venlafaxine; oral
6.1
18.1
43
105
N06AX11
ATC
mirtazapine; oral
5.4
17.8
66
236
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
9.0
17.3
24
33
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
7.5
17.2
29
50
N06AB03
ATC
fluoxetine; oral
6.5
16.5
33
68
N07BB01
ATC
disulfiram; oral
8.2
16.0
24
36
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
6.0
15.8
35
79
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.2
15.5
45
129
188
Kela drug reimbursment
Psychosis requiring demanding treatment
92.7
15.0
16
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
6.3
14.8
30
62
N05AA01
ATC
chlorpromazine; systemic, rectal
35.3
14.4
18
6
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
35.3
14.4
18
6
K08.3
ICD-10 Finland
Retained dental root
6.8
14.3
26
48
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
5.4
14.2
36
91
Z2446
NOMESCO Finland
Social worker
7.8
14.2
22
34
N05AF05
ATC
zuclopenthixol; systemic
46.1
13.6
16
*
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
46.1
13.6
16
*
R42
ICD-10 Finland
Dizziness and giddiness
5.1
13.5
36
95
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
22.6
13.5
19
10
N05BE01
ATC
buspirone; oral
14.1
13.0
22
19
F20
ICD-10 Finland
Schizophrenia
36.9
13.0
16
5
B18.2
ICD-10 Finland
Chronic viral hepatitis C
23.5
13.0
18
9
F20.0
ICD-10 Finland
Paranoid schizophrenia
79.2
12.9
14
*
C07AB07
ATC
bisoprolol; oral
4.2
12.9
59
235
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
18.8
12.7
19
12
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
30.7
12.4
16
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
12.3
64
277
K59.09
ICD-10 Finland
Constipation, unspecified
14.9
12.2
20
16
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
6.4
11.9
22
41
P99
ICPC
Psychological disorders other
10.4
11.8
23
27
A28
ICPC
Limited function/disability NOS
6.3
11.6
22
42
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
28.6
11.5
15
6
ZY010
NOMESCO Finland
Hospital outpatient
6.8
11.5
20
35
EBA00
NOMESCO Finland
Extraction of tooth
3.8
11.1
64
291
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
11.9
11.1
20
20
AA400
NOMESCO Finland
Electroconvulsive therapy
31.7
11.0
14
5
N03AX16
ATC
[U] pregabalin
4.2
10.5
37
119
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.9
10.5
21
42
OAB43, ,
SPAT
0.1
10.2
5
339
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
9.3
10.2
21
27
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
9.9
10.1
20
24
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
29.1
10.1
13
5
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
29.1
10.1
13
5
N05AN01
ATC
lithium; oral
11.7
10.0
18
18
SPAT1240
SPAT
Therapeutic discussion
4.3
9.9
31
91
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
60.4
9.8
11
*
P19
ICPC
Drug abuse
60.4
9.8
11
*
N03AF02
ATC
oxcarbazepine; oral
12.3
9.7
17
16
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.8
9.7
25
63
F20.3
ICD-10 Finland
Undifferentiated schizophrenia
33.3
9.6
12
*
G40
ICD-10 Finland
Epilepsy
24.3
9.6
13
6
F13.29
ICD-10 Finland
Addiction caused by sedative and hypnotic UNS
108.9
9.6
10
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
9.3
9.3
19
24
ZY000
NOMESCO Finland
Hospital inpatient
17.6
9.3
14
9
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
5.5
9.2
20
43
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
40.3
9.2
11
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
14.2
9.2
15
12
R41.0
ICD-10 Finland
Disorientation, unspecified
26.6
9.1
12
5
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
13.1
8.9
15
13
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
7.9
8.9
20
30
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.1
8.8
21
49
IEV99
NOMESCO Finland
Other psychiatric network intervention
54.4
8.8
10
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
5.2
8.8
20
45
A46
ICD-10 Finland
Erysipelas
4.8
8.7
22
54
IGV01
NOMESCO Finland
Psychiatric network contact
22.2
8.7
12
6
N05CF02
ATC
zolpidem; oral
3.7
8.6
34
117
R25.1
ICD-10 Finland
Tremor, unspecified
14.3
8.6
14
11
N05AE03
ATC
sertindole; oral
97.1
8.5
9
*
N05AX15
ATC
cariprazine; oral
97.1
8.5
9
*
R53
ICD-10 Finland
Malaise and fatigue
3.6
8.5
37
136
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
16.1
8.4
13
9
N88
ICPC
Epilepsy
+∞
8.4
8
*
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
+∞
8.4
8
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
4.0
8.4
29
91
F10.24
ICD-10 Finland
Alcohol depence active use
19.0
8.3
12
7
N06AA12
ATC
doxepin; systemic
8.9
8.2
17
22
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
36.3
8.2
10
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
36.3
8.2
10
*
P98
ICPC
Psychosis NOS/other
24.2
8.2
11
5
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
24.2
8.2
11
5
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
7.4
8.2
19
30
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
10.6
8.1
15
16
P15
ICPC
Chronic alcohol abuse
10.6
8.1
15
16
N05AC02
ATC
thioridazine; oral
16.6
7.9
12
8
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
5.0
7.8
18
41
183
Kela drug reimbursment
Lamotrigin and topiramate
27.2
7.7
10
*
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
27.2
7.7
10
*
G72.8
ICD-10 Finland
Other specified myopathies
27.2
7.7
10
*
N03AX14
ATC
levetiracetam; systemic
14.8
7.6
12
9
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
14.8
7.6
12
9
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
10.5
7.5
14
15
WYA20
NOMESCO Finland
Home visit
85.6
7.5
8
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
8.3
7.5
16
22
K02.1
ICD-10 Finland
Caries of dentine
3.7
7.5
89
581
IGY02
NOMESCO Finland
Psychiatric monitoring contact
7.5
7.5
17
26
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
+∞
7.4
7
*
SFA10
NOMESCO Finland
One-surface restoration
3.4
7.3
84
533
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.7
7.3
18
31
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
21.8
7.3
10
5
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
13.3
7.3
12
10
ZXY60
NOMESCO Finland
2-person team, nurses
32.3
7.3
9
*
N05BA02
ATC
chlordiazepoxide; systemic
32.3
7.3
9
*
IGY02, ,
SPAT
32.3
7.3
9
*
XF400
NOMESCO Finland
ECG with 12 standard connections
3.8
7.2
25
78
SPAT1254
SPAT
Administration of medicine
4.0
7.2
23
68
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
7.1
30
107
F61.0
ICD-10 Finland
Mixed personality disorders
15.1
7.1
11
8
SFA30
NOMESCO Finland
Three-surface restoration
2.9
7.0
60
321
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.5
7.0
29
102
A10BA02
ATC
metformin; oral
3.3
7.0
32
120
F10.20
ICD-10 Finland
Alcohol dependence currently independent
12.1
7.0
12
11
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
12.1
7.0
12
11
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
18.1
6.9
10
6
N06AX03
ATC
mianserin; oral
8.7
6.9
14
18
N06AX12
ATC
bupropion; oral
4.1
6.8
21
60
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
7.7
6.8
15
22
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
13.4
6.7
11
9
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
11.0
6.7
12
12
WX110
NOMESCO Finland
Infiltration anesthesia
4.0
6.7
95
666
S04
ICPC
Lump/swelling localized
4.1
6.7
20
56
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
6.3
6.6
17
31
EBA05
NOMESCO Finland
Complicated extraction of tooth
3.0
6.6
38
163
SPAT1301
SPAT
No procedures
2.9
6.6
42
191
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.4
6.6
18
47
EBA15
NOMESCO Finland
Extraction of multiple teeth
9.0
6.5
13
16
Z72.2
ICD-10 Finland
Drug use
73.9
6.5
7
*
N05AL01
ATC
sulpiride; systemic
12.0
6.5
11
10
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
6.5
6.4
16
28
SPAT1243
SPAT
Psychiatric/psychological examination
7.0
6.4
15
24
N03AX12
ATC
[U] gabapentin; oral
3.4
6.4
27
96
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
28.5
6.3
8
*
R40.2
ICD-10 Finland
Coma, unspecified
+∞
6.3
6
*
2959A
ICD-9 Finland
Schizophrenic psychoses, Unspecified schizophrenia[ERILAISTUMATON SKITSOFRENIA,TARKEMMIN MÄÄRITTELEMÄT]
+∞
6.3
6
*
IFC01, ,
SPAT
+∞
6.3
6
*
F12.1
ICD-10 Finland
Mental and behavioural disorders due to use of cannabinoids, harmful use
+∞
6.3
6
*
F13.24
ICD-10 Finland
Addiction relationship caused by sedative and hypnotic active addiction
+∞
6.3
6
*
F13.21
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but staying in a controlling environment
+∞
6.3
6
*
N05AE04
ATC
ziprasidone; systemic
13.6
6.2
10
8
S29
ICPC
Skin symptom/complaint other
3.2
6.2
30
116
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
10.9
6.2
11
11
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
10.9
6.2
11
11
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
6.2
34
142
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
16.1
6.0
9
6
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.6
6.0
22
71
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
84
303
8.29
24.32
7.0
7.5
1.19
1.22
mmol/l
3.11
76
284
83
340
6.71
19.51
7.9
8.6
1.20
1.22
mmol/l
1.53
72
299
24
35
8.47
16.42
1.6
1.3
—
—
—
0
0
24
35
8.47
16.42
3.8
2.3
0.64
0.75
%
0.69
24
35
36
82
6.02
16.15
7.1
9.6
103.19
103.57
mmol/l
0.15
36
82
38
92
5.76
15.94
1.7
1.6
1435.91
1278.16
nmol/l
0.30
33
73
73
302
5.14
15.94
4.8
5.1
34.65
37.27
g/l
2.65
67
289
24
38
7.78
15.26
6.2
14.3
0.80
0.74
%
0.19
24
38
36
87
5.64
15.06
2.1
1.5
—
—
—
0
0
24
39
7.58
14.90
6.2
14.0
1.96
1.88
%
0.05
24
39
35
84
5.63
14.73
1.9
1.5
—
—
—
0
0
65
258
4.67
14.66
3.8
2.8
43.39
55.26
u/l
3.52
59
243
63
250
4.51
14.08
2.3
1.7
100.41
93.63
pmol/l
0.77
42
125
42
124
4.84
13.77
2.1
1.8
—
—
—
0
0
61
245
4.31
13.22
2.9
3.5
2.33
2.35
mmol/l
0.69
52
223
16
5
36.94
12.97
1.7
1.6
14.97
18.24
umol/l
—
16
5
22
38
6.97
12.83
6.5
14.5
91.37
93.09
%
0.42
22
38
80
411
4.39
11.84
7.3
6.6
7.66
10.46
umol/l
4.16
75
392
19
20
11.21
10.26
6.4
4.3
3.74
3.93
mmol/l
0.67
19
20
19
24
9.31
9.32
6.4
7.0
1.23
1.18
mmol/l
0.13
19
24
34
113
3.90
9.14
2.2
2.8
2.43
2.42
mmol/l
0.30
26
104
64
319
3.38
9.12
2.5
2.5
64.98
74.62
nmol/l
1.89
58
290
13
9
16.14
8.44
2.2
1.6
—
—
—
0
0
28
93
3.69
7.41
16.3
6.4
—
—
—
0
0
94
640
4.06
7.28
5.7
3.9
14.28
14.61
pmol/l
0.66
88
596
54
270
2.95
7.23
3.9
2.8
—
—
—
0
0
53
271
2.83
6.69
5.3
3.1
52.48
23.47
ng/l
0.48
41
158
102
786
4.67
6.55
7.2
4.5
1.85
1.78
mu/l
0.25
94
736
86
607
2.85
5.21
3.9
3.6
10.92
8.31
mm/h
0.71
78
569
18
56
3.64
5.16
1.4
1.7
—
—
—
0
0
51
284
2.47
5.11
12.7
9.8
1.12
1.18
inr
0.16
14
85
10
14
7.72
4.77
1.3
1.4
—
—
—
0
0
10
14
7.72
4.77
1.3
1.4
—
—
—
0
0
35
169
2.56
4.68
2.1
1.8
1.03
0.91
mg/l
0.12
28
128
14
41
3.76
4.35
2.1
1.5
—
—
—
0
0
30
139
2.59
4.34
2.8
2.1
0.56
0.79
e6/l
0.28
16
74
40
219
2.29
3.99
3.6
2.5
0.17
0.31
e6/l
0.62
31
166
92
712
2.71
3.95
8.0
2.9
50.89
40.47
u/l
0.96
87
684
101
839
3.26
3.43
6.7
3.5
6.27
5.74
mmol/l
2.79
94
780
8
14
6.06
3.40
1.1
1.1
—
—
—
0
0
105
914
3.75
3.38
29.5
11.7
22.60
21.34
mg/l
0.20
97
684
6
7
8.97
3.30
1.2
1.0
1122.67
1826.14
miu/ml
—
6
7
8
15
5.65
3.25
1.1
1.1
—
—
—
0
0
6
8
7.84
3.09
5.2
1.1
—
—
—
0
0
28
149
2.18
2.90
3.1
3.3
656.62
662.55
ng/l
0.01
21
119
32
185
2.03
2.66
3.8
4.1
17.67
5.70
mg/mmol
0.58
24
127
8
20
4.22
2.62
1.1
1.3
—
—
—
0
0
36
223
1.91
2.44
7.2
3.1
0.00
0.00
estimate
—
5
82
5
8
6.48
2.39
6.6
3.3
33480.00
34562.50
ug/l
—
5
8
23
123
2.10
2.33
3.5
2.2
1.73
3.19
e6/l
—
10
59
5
9
5.75
2.23
1.4
1.4
—
—
—
0
0
5
9
5.75
2.23
1.4
1.4
—
—
—
0
0
24
133
2.03
2.22
4.3
3.1
13.30
118.97
ng/l
1.36
17
86
57
423
1.71
2.06
6.0
3.0
0.00
0.00
estimate
—
7
87
7
21
3.48
2.00
1.1
1.7
—
—
—
0
0
14
66
2.28
1.91
3.5
3.3
—
—
—
0
0
57
431
1.66
1.87
6.0
3.0
0.00
0.00
estimate
—
6
80
98
863
2.16
1.86
21.5
10.1
97.64
93.11
ml/min/173m2
1.15
76
694
6
17
3.67
1.86
7.7
1.6
23.38
23.76
mmol/l
—
6
17
5
12
4.31
1.84
1.8
2.4
—
—
—
0
0
6
18
3.46
1.77
1.5
1.4
—
—
—
0
0
6
19
3.28
1.68
1.2
1.1
—
—
—
0
0
55
422
1.60
1.64
7.1
4.2
0.00
0.00
estimate
—
7
85
7
26
2.80
1.61
1.0
2.4
166.43
177.50
%
—
7
26
7
27
2.70
1.54
1.3
2.3
89.43
96.33
%
—
7
27
5
15
3.44
1.54
1.4
1.9
—
—
—
0
0
5
15
3.44
1.54
1.4
1.9
—
—
—
0
0
5
15
3.44
1.54
1.2
1.1
—
—
—
0
0
12
220
0.49
1.53
2.1
2.3
—
—
—
0
0
14
73
2.05
1.52
1.6
2.0
346.71
400.83
nmol/l
0.46
14
66
6
24
2.58
1.32
1.3
1.6
—
—
—
0
0
6
24
2.58
1.32
1.3
1.6
—
—
—
0
0
12
206
0.53
1.24
2.1
2.2
—
—
—
0
0
5
19
2.71
1.23
1.0
1.1
—
—
—
0
0
8
40
2.08
1.14
1.4
1.3
—
—
—
0
0
30
217
1.52
1.09
1.3
1.3
2.00
2.01
u/ml
0.00
12
62
43
337
1.45
1.06
6.6
2.9
—
—
—
0
0
69
782
0.69
1.05
3.8
3.6
—
—
—
0
0
0
29
0.00
0.99
0.0
1.5
—
—
—
0
0
0
29
0.00
0.99
0.0
1.5
—
—
—
0
0
0
29
0.00
0.99
0.0
1.5
—
—
—
0
0
99
918
1.73
0.97
6.0
3.8
2.74
2.91
mmol/l
1.20
90
869
98
911
1.65
0.89
5.5
3.6
1.24
1.42
mmol/l
5.16
92
862
6
31
1.99
0.86
1.3
1.1
—
—
—
0
0
22
157
1.50
0.85
2.9
3.7
18.46
23.40
%
—
7
58
98
914
1.62
0.84
5.7
3.6
4.52
4.77
mmol/l
1.77
92
864
13
82
1.66
0.82
2.1
2.0
—
—
—
0
0
43
351
1.37
0.81
2.8
2.8
—
—
—
0
0
0
24
0.00
0.80
0.0
1.3
—
—
—
0
0
95
884
1.52
0.77
5.1
3.3
1.63
1.33
mmol/l
2.27
89
829
14
96
1.52
0.65
2.1
2.2
—
—
—
0
0
6
40
1.53
0.52
1.2
1.8
7.37
2.54
mg/l
—
6
28
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.9
—
—
—
0
0
0
17
0.00
0.41
0.0
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
3.89
—
0
8
0
18
0.00
0.40
0.0
1.6
—
220.43
—
0
18
5
36
1.41
0.38
3.0
1.4
—
—
—
0
0
11
144
0.74
0.36
1.6
1.3
—
—
—
0
0
20
167
1.24
0.31
3.5
2.6
—
—
—
0
0
5
41
1.23
0.22
1.0
1.7
35.40
41.97
u/l
—
5
34
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
0.12
—
0
10
5
66
0.75
0.17
1.0
1.3
—
—
—
0
0
23
225
1.03
0.00
1.6
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.0
—
172.45
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
6.03
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
5
54
0.92
-0.00
1.4
3.9
2.66
6.94
ug/l
—
5
44
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.4
—
74.57
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
54
0.92
-0.00
2.2
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
12.33
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint EPILEPTIC_SEIZU_RELATED_DRUGS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| EPILEPTIC_SEIZU_RELATED_DRUGS | 5.024 [2.97, 8.51] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 360 males with EPILEPTIC_SEIZU_RELATED_DRUGS died.
Mortality risk
Mortality risk for people of age
years, who have EPILEPTIC_SEIZU_RELATED_DRUGS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 1.073% |
| 5 | No data | 6.186% |
| 10 | No data | 14.248% |
| 15 | No data | 25.592% |
| 20 | No data | 40.267% |
Relationships between endpoints
↥Index endpoint: EPILEPTIC_SEIZU_RELATED_DRUGS – Epileptic seizures related to drugs
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data