Urethritis and urethral syndrome

N14_URETHRITISANDURSYNDR

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N34
  • Hospital discharge: ICD-8 597
  • Cause of death: ICD-10 N34
  • Cause of death: ICD-8 597

2 out of 7 registries used, show all original rules.

865

4. Check minimum number of events

None

865

5. Include endpoints

None

865

6. Filter based on genotype QC (FinnGen only)

865

Control definitions (FinnGen only)

Control exclude
N14_URINOTH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N30-N39
Name in latin
Urethritis et syndroma urethrale

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7952 4797 3097
Only index persons 6830 4132 2698
Unadjusted period prevalence (%)
Whole population 0.12 0.14 0.09
Only index persons 0.13 0.15 0.10
Median age at first event (years)
Whole population 41.23 46.64 32.80
Only index persons 38.67 43.51 31.27

-FinnGen-

Key figures

All Female Male
Number of individuals 865 567 298
Unadjusted period prevalence (%) 0.17 0.19 0.13
Median age at first event (years) 41.41 43.61 37.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
790
Matched controls
7899
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N34.3
ICD-10 Finland
Urethral syndrome, unspecified
+∞
323.0
312
*
UKC02
NOMESCO Finland
Cystoscopy
20.0
230.3
380
349
N30.0
ICD-10 Finland
Acute cystitis
+∞
202.0
185
*
N34.1
ICD-10 Finland
Nonspecific urethritis
1193.7
196.6
184
*
TKD00
NOMESCO Finland
Dilatation of urethra
286.4
180.7
178
8
N34.2
ICD-10 Finland
Other urethritis
295.5
103.4
103
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
14.5
102.4
182
160
N30
ICD-10 Finland
Cystitis
+∞
100.2
94
*
N30.9
ICD-10 Finland
Cystitis, unspecified
+∞
96.9
91
*
R30.0
ICD-10 Finland
Dysuria
26.4
93.1
131
59
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
+∞
87.1
82
*
XKD00
NOMESCO Finland
Uroflowmetry
8.3
82.4
200
309
J01EA01
ATC
trimethoprim; systemic
5.0
79.8
321
948
59709
ICD-8 Finland
Urethritis (non-venereal), Unspecified
+∞
76.3
72
*
KCV04
NOMESCO Finland
Distension of bladder with fluid
167.8
73.4
76
5
J01MA02
ATC
ciprofloxacin; systemic
3.8
66.5
404
1689
J01CA08
ATC
pivmecillinam; oral
3.6
60.3
417
1888
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
7.3
59.3
154
254
59700
ICD-8 Finland
Urethritis (non-venereal), Acuta
+∞
55.9
53
*
G04BD07
ATC
tolterodine; oral
13.3
54.0
97
82
R35
ICD-10 Finland
Polyuria
10.0
52.7
110
126
J02AC01
ATC
fluconazole; systemic
3.0
44.7
403
2057
G04BD04
ATC
oxybutynin; oral, transdermal
8.8
41.5
92
116
N39.4
ICD-10 Finland
Other specified urinary incontinence
12.2
41.1
76
68
N39.3
ICD-10 Finland
Stress incontinence
25.0
39.8
56
24
U01
ICPC
Dysuria/painful urination
7.0
39.4
102
163
G04BD12
ATC
mirabegron; oral
6.3
38.8
109
195
N34.0
ICD-10 Finland
Urethral abscess
+∞
37.8
36
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
3.3
37.7
235
908
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.8
37.7
342
1697
XKC03
NOMESCO Finland
Water cystometry
37.5
36.3
46
13
U02
ICPC
Urinary frequency/urgency
4.3
34.7
141
379
J01MA06
ATC
norfloxacin; oral
3.9
34.2
157
472
G04BD08
ATC
solifenacin; oral
7.7
33.8
81
115
N30.2
ICD-10 Finland
Other chronic cystitis
+∞
32.5
31
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.2
31.9
131
354
R33
ICD-10 Finland
Retention of urine
6.6
31.9
85
141
U07
ICPC
Urine symptom/complaint other
6.8
31.4
82
132
59702
ICD-8 Finland
Urethritis (non-venereal), Chronica
+∞
29.3
28
*
N03AX16
ATC
pregabalin; oral
2.8
27.7
221
975
A02BC05
ATC
esomeprazole; systemic
2.3
27.2
350
1999
XKD06
NOMESCO Finland
Physiologic investigation of micturition
21.5
26.7
39
19
XKD03
NOMESCO Finland
Urethral pressure profilometry
75.0
25.9
29
*
U05
ICPC
Urination problems other
7.3
25.6
63
93
P01AB01
ATC
metronidazole; oral, rectal
2.3
25.6
341
1965
TKC20
NOMESCO Finland
Catheterisation of bladder
5.0
24.9
83
180
J01DB01
ATC
cefalexin; oral
2.6
24.9
661
5241
A02BC02
ATC
pantoprazole; systemic
2.2
24.8
524
3707
N02AX02
ATC
tramadol; systemic, rectal
2.2
24.2
346
2046
J01MA01
ATC
ofloxacin; systemic
4.1
24.0
100
272
A06AC01
ATC
ispaghula (psylla seeds); oral
2.5
23.8
221
1050
R53
ICD-10 Finland
Malaise and fatigue
2.7
23.4
187
814
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
23.3
248
1264
J01MA12
ATC
levofloxacin; systemic
2.9
22.9
160
643
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.4
22.4
233
1168
G04CA02
ATC
tamsulosin; oral
2.9
22.3
154
613
A02BC03
ATC
lansoprazole; oral
2.3
22.3
255
1344
R30.1
ICD-10 Finland
Vesical tenesmus
14.4
21.5
36
26
G04AC01
ATC
NA
8.0
21.4
49
65
N06AA09
ATC
amitriptyline; systemic
3.4
21.0
111
366
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.3
21.0
251
1344
KDW96
NOMESCO Finland
Other operations on urethra
+∞
20.9
20
*
R10.2
ICD-10 Finland
Pelvic and perineal pain
8.6
20.7
45
55
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
215.4
20.7
21
*
R30.9
ICD-10 Finland
Painful micturition, unspecified
23.1
20.5
29
13
U13
ICPC
Bladder symptom/complaint other
10.5
20.1
39
39
N35.9
ICD-10 Finland
Urethral stricture, unspecified
+∞
19.9
19
*
J01XE01
ATC
nitrofurantoin; oral
11.4
19.9
37
34
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.0
19.8
371
2394
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.1
19.6
119
432
TKW99
NOMESCO Finland
Other minor surgical procedure in urology
41.2
19.6
24
6
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
19.5
153
654
N03AX12
ATC
gabapentin; oral
2.7
19.2
143
592
U29
ICPC
Urinary symptom/complaint other
11.8
19.1
35
31
R31
ICD-10 Finland
Unspecified haematuria
3.8
18.3
81
231
U71
ICPC
Cystitis/urinary infection other
4.6
17.9
63
145
1530
FHL
Urethrocystoscopy
10.1
17.8
35
36
A02BA02
ATC
ranitidine; systemic
2.4
17.8
174
834
M79.6
ICD-10 Finland
Pain in limb
2.0
17.7
284
1700
A02BC01
ATC
omeprazole; systemic
2.2
17.7
226
1231
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.5
17.5
52
99
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
17.5
220
1188
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
5.6
17.4
51
96
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
17.2
150
677
ZX136
NOMESCO Finland
Intravesicalis
32.3
17.1
22
7
UJF32
NOMESCO Finland
Coloscopy
2.2
17.1
211
1128
J01AA02
ATC
doxycycline; systemic
2.0
17.0
607
4885
LEG10
NOMESCO Finland
Vaginal urethrocystopexy
+∞
16.7
16
*
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
+∞
16.7
16
*
M01AH05
ATC
etoricoxib; oral
1.9
16.5
459
3349
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
16.2
118
479
N06AX11
ATC
mirtazapine; oral
2.0
16.0
262
1566
R03BA05
ATC
fluticasone; inhalant
2.4
16.0
154
728
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
3.8
15.9
70
199
S01GX01
ATC
cromoglicic acid; ophthalmic
2.3
15.8
170
847
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.8
15.6
108
424
L03
ICPC
Low back symptom/complaint
2.1
15.5
199
1076
G04BD11
ATC
fesoterodine; oral
8.6
15.4
33
40
SPAT1167
SPAT
Insertion of urinary catheter
7.7
15.3
35
47
R01AD09
ATC
mometasone; nasal
1.9
15.3
360
2454
N06AX16
ATC
venlafaxine; oral
2.5
15.2
127
555
204
Kela drug reimbursment
Leukemia lymphatica
4.5
15.1
54
127
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
14.8
317
2082
N05BA04
ATC
oxazepam; oral
2.1
14.8
210
1181
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
14.8
342
2306
M54.5
ICD-10 Finland
Low back pain
1.9
14.7
264
1626
N36.1
ICD-10 Finland
Urethral diverticulum
+∞
14.6
14
*
7362
FHL
Urethral dilatation in anesthesia or operating room
+∞
14.6
14
*
59708
ICD-8 Finland
Urethritis (non-venereal), Alia definita
+∞
14.6
14
*
7325
FHL
Bladder stretching
152.7
14.5
15
*
D01
ICPC
Abdominal pain/cramps general
2.7
14.5
106
431
G04CA01
ATC
alfuzosin; oral
3.1
14.5
82
283
N06AX21
ATC
duloxetine; oral
2.8
14.3
95
365
R03AC02
ATC
salbutamol; inhalant
1.8
14.2
404
2906
N76.0
ICD-10 Finland
Acute vaginitis
3.8
14.1
61
171
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
14.1
291
1878
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.8
14.1
333
2250
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
14.0
203
1149
J01DA01
ATC
[U] cefalexin; systemic
1.8
13.7
490
3773
N30.8
ICD-10 Finland
Other cystitis
+∞
13.6
13
*
H02AB06
ATC
prednisolone; systemic
1.8
13.5
357
2493
K30
ICD-10 Finland
Functional dyspepsia
2.8
13.5
91
353
N05AH04
ATC
quetiapine; oral
2.3
13.5
138
668
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.9
13.4
83
305
R06AX27
ATC
desloratadine; oral
1.9
13.4
223
1329
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
13.3
395
2857
G03CA04
ATC
estriol; systemic, vaginal
3.2
13.2
72
243
R06.0
ICD-10 Finland
Dyspnoea
2.0
13.2
188
1052
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.2
13.1
71
238
G04BD09
ATC
trospium; oral
8.5
13.1
28
34
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
28.9
13.0
17
6
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.8
13.0
43
94
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.2
12.9
139
691
R51.80
ICD-10 Finland
Headache
2.3
12.8
127
607
G44.2
ICD-10 Finland
Tension-type headache
2.4
12.7
115
524
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.2
12.6
66
216
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
+∞
12.5
12
*
G04AB05
ATC
NA
5.8
12.5
35
63
C05AA08
ATC
fluocortolone; rectal, topical
2.3
12.4
122
577
J01FA10
ATC
azithromycin; systemic
1.7
12.4
446
3392
J01XX05
ATC
methenamine; oral
14.6
12.3
20
14
R4110
NOMESCO Finland
Physiotherapy
1.9
12.3
203
1199
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.5
12.3
58
176
J02AC02
ATC
itraconazole; systemic
2.1
12.2
156
832
N94.1
ICD-10 Finland
Dyspareunia
7.1
12.2
29
42
N02BE01
ATC
paracetamol; systemic, rectal
1.9
12.1
654
5630
M03BC01
ATC
orphenadrine (citrate); systemic
2.0
12.0
190
1102
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
12.0
174
978
M79.1
ICD-10 Finland
Myalgia
2.4
11.9
109
499
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.2
11.8
134
680
WX320
NOMESCO Finland
Spinalanesthesy
2.0
11.8
173
975
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.7
11.8
81
318
F45.8
ICD-10 Finland
Other somatoform disorders
3.0
11.8
71
254
M25.5
ICD-10 Finland
Pain in joint
1.9
11.7
219
1348
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
11.7
90
377
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
65.9
11.6
13
*
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.8
11.6
48
131
K10.3
ICD-10 Finland
Alveolitis of jaws
4.0
11.5
46
121
5951A
ICD-9 Finland
Cystitis, Chronic interstitial cystitis
+∞
11.5
11
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
11.4
105
483
JAH01
NOMESCO Finland
Laparoscopy
3.6
11.4
51
148
R52.2
ICD-10 Finland
Other chronic pain
5.1
11.4
35
71
R52.9
ICD-10 Finland
Pain, unspecified
2.8
11.3
74
281
G01AF05
ATC
econazole; vaginal
2.7
11.3
81
326
R07.0
ICD-10 Finland
Pain in throat
3.3
11.3
56
177
A06AD11
ATC
lactulose; oral
2.3
11.1
107
501
A07AA02
ATC
nystatin; oral
3.2
11.1
58
190
R39.1
ICD-10 Finland
Other difficulties with micturition
6.0
11.1
30
52
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.7
11.1
412
3121
KDV12
NOMESCO Finland
Urethroscopic internal urethrotomy
43.9
10.9
13
*
J01MA04
ATC
enoxacin; oral
7.9
10.9
24
31
A02BC04
ATC
rabeprazole; oral
2.7
10.8
74
288
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.5
10.8
87
373
M01AH01
ATC
celecoxib; oral (coxibs)
2.0
10.8
148
812
R32
ICD-10 Finland
Unspecified urinary incontinence
6.5
10.7
27
43
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
10.6
84
357
N06AB04
ATC
citalopram; systemic
1.9
10.6
171
997
X15
ICPC
Vaginal symptom/complaint other
4.3
10.6
38
91
R30
ICD-10 Finland
Pain associated with micturition
111.4
10.4
11
*
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
+∞
10.4
10
*
6256A
ICD-9 Finland
Pain and other symptoms associated with female genital organs, Stress incontinence, female
+∞
10.4
10
*
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
10.2
138
748
M79.7
ICD-10 Finland
Fibromyalgia
4.6
10.2
34
76
M01AB05
ATC
diclofenac; systemic, rectal
1.6
10.1
487
3911
N05CF01
ATC
zopiclone; oral
1.7
10.1
235
1542
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.8
10.1
64
240
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
14.8
10.0
16
11
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
9.8
522
4289
N06AB06
ATC
sertraline; oral
2.3
9.8
91
419
A04
ICPC
Weakness/tiredness general
2.2
9.8
103
504
M03BX02
ATC
tizanidine; oral
1.6
9.8
453
3587
G01AA10
ATC
clindamycin; vaginal
2.1
9.7
116
600
A03CA02
ATC
clidinium and psycholeptics; oral
3.0
9.7
55
191
R01AD08
ATC
fluticasone; nasal
1.7
9.6
218
1414
TKC22
NOMESCO Finland
Catheterisation instruction
11.6
9.6
17
15
R01AD12
ATC
fluticasone furoate; nasal
1.7
9.5
221
1445
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
9.5
123
656
359
Kela drug reimbursment
Mirabegroni
101.2
9.4
10
*
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
101.2
9.4
10
*
G04BD
ATC
Drugs for urinary frequency and incontinence
101.2
9.4
10
*
KCW96
NOMESCO Finland
Other operations on bladder
30.4
9.4
12
*
J05AB01
ATC
aciclovir; systemic
1.9
9.4
163
969
J01CA04
ATC
amoxicillin; systemic
1.7
9.4
618
5342
Z71.8
ICD-10 Finland
Other specified counselling
1.8
9.4
182
1124
59701
ICD-8 Finland
Urethritis (non-venereal), Recidivans
+∞
9.4
9
*
N94.2
ICD-10 Finland
Vaginismus
22.0
9.4
13
6
C07AA05
ATC
propranolol; systemic
1.9
9.4
156
914
WX110
NOMESCO Finland
Local anesthesy
1.6
9.3
512
4210
J01FA06
ATC
roxithromycin; oral
1.6
9.3
302
2167
M01AH02
ATC
rofecoxib; oral
2.1
9.3
106
535
SPAT1254
SPAT
Administration of medicine
2.1
9.3
114
593
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.6
9.2
65
260
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.3
9.0
45
144
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
9.0
79
355
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.3
9.0
82
376
A03FA02
ATC
cisapride; oral, rectal
2.6
8.9
66
269
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
8.9
152
898
M70.6
ICD-10 Finland
Trochanteric bursitis
2.2
8.8
94
460
R20.2
ICD-10 Finland
Paraesthesia of skin
2.8
8.8
55
204
R12
ICD-10 Finland
Heartburn
2.7
8.8
59
229
M01AE02
ATC
naproxen; oral, rectal
1.6
8.7
421
3323
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
8.7
161
978
R42
ICD-10 Finland
Dizziness and giddiness
1.8
8.7
154
923
M01AE01
ATC
ibuprofen; systemic, rectal
1.8
8.7
678
6071
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.6
8.7
37
105
U04
ICPC
Incontinence urine
4.1
8.6
32
80
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.8
8.6
54
200
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
4.5
8.6
29
66
A01
ICPC
Pain general/multiple sites
2.6
8.6
63
258
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
8.5
212
1409
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
8.5
154
928
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.3
8.5
80
370
D11
ICPC
Diarrhoea
2.2
8.4
85
408
N04BC05
ATC
pramipexole; oral
2.6
8.4
61
248
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
8.4
161
988
H02AB07
ATC
prednisone; oral
2.0
8.4
113
611
M54
ICD-10 Finland
Dorsalgia
2.2
8.4
89
438
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
+∞
8.3
8
*
59504
ICD-8 Finland
Cystitis, Interstitialis (Hunner)
+∞
8.3
8
*
N35.8
ICD-10 Finland
Other urethral stricture
+∞
8.3
8
*
7434
FHL
Abdominal urethrocystopexy
+∞
8.3
8
*
N07AA03
ATC
distigmine; systemic
+∞
8.3
8
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
8.3
97
495
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.8
8.3
156
952
N05CD07
ATC
temazepam; oral
2.2
8.3
88
430
G43.9
ICD-10 Finland
Migraine, unspecified
2.7
8.3
54
207
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.2
8.2
88
434
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
3.0
8.2
47
165
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
5.8
8.2
22
39
D19
ICPC
Teeth/gum symptom/complaint
1.7
8.2
189
1227
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.3
8.1
71
319
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.2
8.1
83
402
AA1AD
NOMESCO Finland
CT of head and brain
1.8
8.1
160
991
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
8.1
93
471
K08.80
ICD-10 Finland
Toothache NOS
2.5
8.1
64
271
Z01.2
ICD-10 Finland
Dental examination
1.6
8.1
298
2192
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.2
8.1
85
417
K59.09
ICD-10 Finland
Constipation, unspecified
3.0
8.1
46
161
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
8.0
289
2114
K07.60
ICD-10 Finland
Snapping jaw
3.1
7.9
42
141
D06
ICPC
Abdominal pain localized other
2.4
7.9
67
297
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
6.2
7.9
20
33
H02AB04
ATC
methylprednisolone; systemic
2.0
7.9
111
610
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
10.9
7.8
14
13
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
7.7
269
1944
UKD02
NOMESCO Finland
Urethroscopy
45.4
7.7
9
*
A01AB09
ATC
miconazole; local oral
2.2
7.7
75
353
SPAT1263
SPAT
Sampling
1.5
7.7
311
2333
TAC99
NOMESCO Finland
Other blockade for chronic pain
18.6
7.6
11
6
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.4
7.6
61
261
L28
ICPC
Limited function/disability (L)
2.0
7.6
104
569
N03AG01
ATC
valproic acid; systemic, rectal
2.7
7.6
50
194
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
7.6
169
1083
L02
ICPC
Back symptom/complaint
2.2
7.6
72
337
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
7.6
123
712
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.9
7.5
44
158
N36.8
ICD-10 Finland
Other specified disorders of urethra
80.8
7.4
8
*
N94.8
ICD-10 Finland
Other specified conditions associated with female genital organs and menstrual cycle
80.8
7.4
8
*
N02AA05
ATC
oxycodone; systemic
2.0
7.4
93
491
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.0
7.4
99
536
R07.3
ICD-10 Finland
Other chest pain
2.3
7.4
68
311
D07AD01
ATC
clobetasol; topical
1.9
7.4
113
640
J01FF01
ATC
clindamycin; systemic
1.6
7.4
196
1317
R02
ICPC
Shortness of breath/dyspnoea
2.1
7.4
84
424
R96
ICPC
Asthma
2.3
7.4
68
313
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.4
7.3
34
104
N32.0
ICD-10 Finland
Bladder-neck obstruction
+∞
7.3
7
*
N36.2
ICD-10 Finland
Urethral caruncle
15.9
7.2
11
7
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
7.2
344
2665
N95.0
ICD-10 Finland
Postmenopausal bleeding
2.3
7.2
63
284
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
7.4
7.2
16
22
N05CF02
ATC
zolpidem; oral
1.8
7.2
130
780
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
7.2
201
1372
Y6099
ICD-8 Finland
Prenatal care and observation
2.9
7.2
41
144
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
7.2
164
1059
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.1
7.1
36
118
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
7.1
111
637
R50.9
ICD-10 Finland
Fever, unspecified
2.0
7.0
96
523
R05
ICD-10 Finland
Cough
1.8
7.0
132
801
J01FA09
ATC
clarithromycin; systemic
1.6
7.0
230
1631
SPAT1312
SPAT
General health counselling
1.6
7.0
230
1634
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
7.0
117
684
N05BA01
ATC
diazepam; systemic, rectal
1.9
7.0
101
562
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
2.6
7.0
48
189
N17
ICPC
Vertigo/dizziness
2.1
7.0
81
412
N76.8
ICD-10 Finland
Other specified inflammation of vagina and vulva
6.4
7.0
17
27
LEB00
NOMESCO Finland
Biopsy of vagina
6.4
7.0
17
27
N77.1*B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
5.9
6.9
18
31
SPAT1211
SPAT
Application of soft bandage
2.2
6.9
68
324
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
13.9
6.9
11
8
J01MA14
ATC
moxifloxacin; systemic
2.2
6.9
67
315
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
6.8
102
575
G01AF04
ATC
miconazole; vaginal
2.8
6.8
41
151
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
9.4
6.8
13
14
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
6.8
382
3054
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
6.8
217
1527
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.3
6.8
32
100
N32.9
ICD-10 Finland
Bladder disorder, unspecified
40.4
6.8
8
*
LWW96
NOMESCO Finland
Other reoperation in gynaecological surgery
40.4
6.8
8
*
L13
ICPC
Hip symptom/complaint
1.8
6.7
111
646
S18
ICPC
Laceration/cut
1.5
6.7
274
2045
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
5.0
6.7
20
41
R05
ICPC
Cough
1.7
6.7
158
1026
R06AE07
ATC
cetirizine; oral
1.5
6.7
315
2424
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
6.7
200
1384
WX002
NOMESCO Finland
Sedation and analgesia
1.7
6.7
132
815
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
6.6
205
1432
R03BA01
ATC
beclometasone; inhalant
1.9
6.6
102
581
N05BA12
ATC
alprazolam; oral
2.0
6.6
81
423
Z00.0
ICD-10 Finland
General medical examination
1.7
6.6
130
804
J20
ICD-10 Finland
Acute bronchitis
2.1
6.6
68
332
J01DC02
ATC
cefuroxime; systemic
2.5
6.6
49
203
N41.9
ICD-10 Finland
Inflammatory disease of prostate, unspecified
10.1
6.5
12
12
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
6.5
69
338
D07AC13
ATC
mometasone; topical
1.6
6.5
207
1456
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.1
6.4
23
57
N34
ICD-10 Finland
Urethritis and urethral syndrome
70.4
6.4
7
*
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
7.5
6.4
14
19
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.3
6.4
55
247
KED33
NOMESCO Finland
Transurethral incision of prostate
14.4
6.4
10
7
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
6.4
54
239
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
5.0
6.4
19
39
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
6.4
57
261
N76.3
ICD-10 Finland
Subacute and chronic vulvitis
6.6
6.4
15
23
U08
ICPC
Urinary retention
6.6
6.4
15
23
J01FA01
ATC
erythromycin; systemic
1.9
6.3
101
579
WX290
NOMESCO Finland
Other blockade of nerve
1.5
6.3
313
2427
R11
ICD-10 Finland
Nausea and vomiting
2.2
6.3
61
288
N89.9
ICD-10 Finland
Noninflammatory disorder of vagina, unspecified
18.2
6.3
9
5
P01BA02
ATC
hydroxychloroquine; oral
2.2
6.3
63
302
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
6.3
119
725
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
+∞
6.3
6
*
M01AC06
ATC
meloxicam; systemic, rectal
1.5
6.2
248
1830
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
6.2
97
554
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
6.2
233
1697
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
4.2
6.2
22
54
LEG12
NOMESCO Finland
Transobturatoric tape
26.9
6.2
8
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
6.2
109
648
R09
ICPC
Sinus symptom/complaint
2.2
6.2
63
304
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
6.2
74
384
E0000UV
ATC
NA
1.5
6.2
274
2070
L29.2
ICD-10 Finland
Pruritus vulvae
5.4
6.2
17
32
K59.1
ICD-10 Finland
Functional diarrhoea
2.7
6.2
40
154
A01AB04
ATC
amphotericin B; local oral
2.5
6.1
44
180
ULA02
NOMESCO Finland
Kolposcopy
2.1
6.1
67
335
M01AB55
ATC
diclofenac, combinations; oral
2.3
6.1
52
230
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
6.1
92
518
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.1
6.1
64
312
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.3
6.1
53
240
N03AE01
ATC
clonazepam; systemic
2.4
6.1
47
200
N06AX26
ATC
vortioxetine; oral
2.4
6.1
49
211
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.1
6.1
64
313
M01AG02
ATC
tolfenamic acid; oral, rectal
1.8
6.1
111
669
WX400
NOMESCO Finland
Inhalation anesthesy
2.9
6.1
35
125
N03AX09
ATC
lamotrigine; oral
2.9
6.1
35
125
L01
ICPC
Neck symptom/complaint
1.8
6.0
97
559
G04BD01
ATC
emepronium; systemic
10.1
6.0
11
11
X23
ICPC
Fear sexually transm dis female
2.7
6.0
37
139
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
6.0
109
656
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.9
6.0
86
477
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
2.2
6.0
59
281

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
368
1623
3.21
59.36
5.6
2.1
—
—
—
0
0
643
4127
3.17
49.46
9.8
3.2
2283.0
1880.4
e6/l
—
8
56
392
2053
2.66
42.66
6.1
2.8
151.6
56.4
e6/l
0.71
293
1382
651
4421
2.91
41.03
8.3
3.5
—
—
—
0
0
340
1703
2.64
39.95
5.4
2.5
28.2
101.5
e6/l
1.11
277
1271
261
1150
2.82
39.45
4.0
2.1
5.2
7.2
e6/l
1.17
236
1011
77
151
5.50
37.94
2.2
2.5
—
—
—
0
0
242
1082
2.72
35.02
4.7
2.3
543.7
554.6
mosm/kgh2o
0.31
213
918
306
1539
2.53
34.73
5.2
2.4
—
—
—
0
0
302
1568
2.42
31.41
5.3
2.5
0.2
0.4
e6/l
1.53
247
1142
486
3110
2.28
30.71
6.3
2.9
0.0
0.0
estimate
0.00
93
587
490
3157
2.27
30.31
6.5
2.9
0.0
0.0
estimate
0.50
97
570
485
3115
2.27
30.19
8.4
4.0
0.0
0.0
estimate
0.39
96
591
190
856
2.56
26.29
4.4
2.3
3.7
3.2
e6/l
0.22
106
437
355
2141
2.12
24.35
6.5
5.5
—
—
—
0
0
661
5067
2.29
23.63
8.5
6.9
76.1
77.2
u/l
0.23
624
4729
182
853
2.44
22.87
1.3
1.2
—
—
—
0
0
466
3157
2.03
22.81
7.2
5.4
56.9
56.9
%
0.03
436
2950
468
3199
2.01
22.07
7.5
5.6
28.7
28.5
%
0.13
436
2975
456
3102
1.99
21.66
7.7
5.9
8.2
8.5
%
1.08
425
2901
486
3386
1.99
21.48
7.0
5.4
2.0
1.9
e9/l
0.17
433
2988
474
3277
1.99
21.39
6.9
5.4
0.6
0.6
e9/l
0.23
415
2839
475
3292
1.98
21.22
7.0
5.4
0.0
0.0
e9/l
0.53
418
2850
323
1963
2.03
20.98
3.0
2.5
54.8
58.3
u/l
1.06
296
1809
451
3087
1.96
20.71
7.4
5.5
2.9
2.8
%
0.65
417
2869
483
3413
1.94
19.88
7.3
5.6
0.2
0.2
e9/l
0.21
430
3009
387
2543
1.94
19.77
2.1
1.8
99.1
96.1
pmol/l
0.52
201
1273
252
1429
2.08
19.56
2.0
1.7
0.8
1.2
mg/l
2.71
192
1069
210
1112
2.17
19.48
1.8
1.7
1146.0
1167.4
nmol/l
0.12
161
828
435
2986
1.92
19.36
7.5
5.6
0.7
0.7
%
0.54
403
2771
443
3063
1.91
19.24
7.6
6.4
1.2
1.2
mmol/l
0.90
373
2583
525
3847
1.93
19.01
10.1
8.4
4.0
4.0
e9/l
0.29
464
3358
466
3312
1.88
18.23
5.8
6.0
10.2
11.0
umol/l
1.46
442
3138
629
4968
1.98
17.37
5.4
3.8
11.6
11.5
mm/h
0.08
586
4582
398
2737
1.84
16.85
2.5
2.2
77.6
76.5
nmol/l
0.32
352
2456
402
2789
1.82
16.41
7.0
5.8
1.2
1.2
mmol/l
0.30
358
2521
239
1407
1.97
16.27
5.7
2.9
—
—
—
0
0
277
1722
1.90
15.97
5.7
2.6
—
—
—
0
0
158
814
2.15
15.41
2.6
2.3
81.9
118.9
ug/g
1.59
128
643
413
2951
1.76
14.76
3.4
2.6
120.1
113.6
ug/l
0.19
381
2712
782
6851
2.47
14.35
21.1
11.7
20.2
22.5
mg/l
1.25
646
5321
118
557
2.30
14.20
2.2
2.1
357.4
389.9
nmol/l
1.14
110
505
373
2626
1.74
13.75
2.3
2.0
—
—
—
0
0
494
3761
1.73
13.70
5.8
4.6
6.5
6.6
mmol/l
1.11
467
3473
138
707
2.13
13.55
1.7
1.5
—
—
—
0
0
789
6988
2.47
13.27
20.7
13.5
139.7
139.7
mmol/l
0.34
770
6793
647
5346
1.83
13.23
5.1
3.9
14.8
14.7
pmol/l
0.18
592
4864
791
7018
2.49
13.17
20.8
13.5
4.0
4.0
mmol/l
0.04
771
6809
189
1099
1.92
13.01
1.4
1.2
13.8
11.5
u/ml
0.15
71
420
243
1562
1.77
12.00
4.3
3.5
93.8
92.1
%
0.53
232
1522
244
1577
1.76
11.80
2.5
2.0
2.8
3.0
mg/l
0.91
211
1329
729
6338
1.96
11.65
6.1
4.6
1.8
1.9
mu/l
1.22
675
5819
190
1144
1.85
11.62
1.4
1.2
17.5
33.8
iu/ml
3.18
63
365
277
1872
1.71
11.34
2.6
2.0
144.5
188.7
u/l
1.15
261
1764
293
2022
1.68
11.04
2.6
2.2
—
—
—
0
0
308
2157
1.66
10.95
3.3
3.3
2.4
2.4
mmol/l
0.40
256
1888
364
2663
1.63
10.87
5.2
4.5
36.1
35.9
g/l
0.33
345
2451
254
1696
1.70
10.78
3.1
3.0
1078.0
1188.7
ng/l
0.24
207
1403
236
1552
1.72
10.56
5.1
3.7
—
—
—
0
0
240
1587
1.71
10.52
7.7
6.4
—
—
—
0
0
108
556
2.08
10.38
3.6
2.4
30.3
46.7
u/l
1.16
96
466
148
853
1.89
10.29
1.5
1.3
667.9
514.8
titre
0.37
33
177
147
851
1.88
10.07
2.1
1.9
—
—
—
0
0
114
614
1.99
9.66
4.2
3.9
—
—
—
0
0
181
1132
1.76
9.59
4.5
3.8
210.8
415.7
ng/l
0.92
129
855
248
1697
1.65
9.39
7.6
3.1
0.0
0.0
estimate
1.08
95
575
121
681
1.90
9.00
1.3
1.3
—
—
—
0
0
81
396
2.15
8.89
5.0
2.2
—
—
—
0
0
402
3123
1.54
8.66
4.0
3.8
—
—
—
0
0
206
1371
1.66
8.60
2.3
1.9
—
—
—
0
0
72
341
2.21
8.55
5.1
3.0
7.4
7.4
ph
0.85
13
43
59
259
2.37
8.36
2.3
1.5
—
—
—
0
0
703
6219
1.70
8.35
6.4
5.3
39.2
39.4
mmol/mol
0.19
653
5772
258
1827
1.59
8.33
4.5
3.6
7.4
7.4
ph
0.22
48
349
152
939
1.75
8.32
2.4
2.2
13.7
13.3
umol/l
0.22
143
862
199
1326
1.65
8.23
1.4
1.4
2.1
2.4
g/l
1.84
125
802
140
850
1.77
8.13
2.3
2.2
2.5
2.4
g/l
0.92
132
777
200
1339
1.64
8.10
1.7
1.7
52663138.2
7424402.0
pmol/l
0.40
169
1118
329
2481
1.53
7.95
8.2
8.1
1.2
1.2
inr
0.01
92
712
132
793
1.78
7.94
2.3
2.2
21.6
22.7
%
0.39
110
668
120
706
1.81
7.73
2.4
2.6
5.8
7.6
umol/l
0.68
97
620
207
1413
1.61
7.72
1.6
1.5
21.9
20.8
nmol/l
0.37
171
1193
124
741
1.79
7.58
1.5
1.4
—
—
—
0
0
33
116
2.92
7.28
4.7
3.1
—
—
—
0
0
253
1836
1.53
7.16
4.6
3.5
—
—
—
0
0
94
527
1.88
7.05
1.2
1.2
—
—
—
0
0
81
433
1.96
7.00
3.6
3.5
77.6
78.3
ng/l
0.03
70
375
785
7252
1.89
6.94
17.4
11.3
—
—
—
0
0
72
371
2.03
6.90
1.5
1.8
1.1
1.3
g/l
0.98
65
340
226
1611
1.55
6.90
2.6
2.3
3902.7
7545.6
umol/l
0.67
195
1394
547
4655
1.48
6.87
4.0
3.6
—
—
—
0
0
314
2402
1.48
6.84
4.6
3.2
38.9
51.5
ng/l
0.24
196
1564
82
444
1.94
6.83
3.2
2.4
19.0
16.3
au/ml
—
9
22
151
981
1.65
6.80
4.6
3.1
0.8
0.8
mmol/l
0.31
145
915
43
181
2.45
6.72
1.3
1.5
404.3
274.7
ug/g
3.07
24
108
51
232
2.27
6.70
1.1
1.2
4.2
1.8
u/ml
—
5
16
76
405
1.96
6.63
1.6
1.3
81.2
31.6
au/ml
—
6
22
202
1418
1.55
6.57
7.1
3.0
1.0
1.0
kg/l
0.82
35
198
793
7371
1.91
6.56
12.7
9.4
25.1
26.6
u/l
1.84
772
7106
115
702
1.74
6.52
17.7
24.0
1.3
1.3
inr
0.23
14
103
85
475
1.88
6.45
3.4
2.8
9.7
10.4
g/l
1.25
80
426
124
786
1.67
6.12
1.9
1.5
—
—
—
0
0
16
39
4.16
6.11
2.2
1.4
5.6
5.7
u/l
0.02
11
32
98
583
1.77
6.07
2.5
2.2
0.2
0.2
g/l
0.15
91
552
729
6653
1.61
6.04
5.1
4.2
5.9
5.9
mmol/l
0.07
666
6057
216
1565
1.51
6.02
2.5
2.1
—
—
—
0
0
210
1513
1.51
6.01
1.3
1.2
2.7
1.4
u/ml
0.36
47
401
75
420
1.86
5.66
1.1
1.2
—
—
—
0
0
78
445
1.83
5.56
2.9
2.8
3.9
4.1
e9/l
0.33
61
342
29
112
2.64
5.43
3.0
2.4
17.3
16.4
%
0.57
18
58
359
2924
1.39
5.18
12.1
8.3
0.0
0.0
e9/l
0.11
297
2381
27
104
2.65
5.10
1.6
1.3
—
—
—
0
0
17
50
3.45
5.04
1.4
1.3
7.4
7.4
g/l
—
10
36
43
206
2.14
5.04
1.4
1.2
—
—
—
0
0
22
77
2.91
4.95
1.5
1.2
—
—
nmol/l
—
0
0
82
493
1.73
4.91
1.5
1.2
99.8
146.0
iu/ml
0.85
29
193
75
441
1.77
4.86
6.8
9.4
—
—
—
0
0
64
359
1.85
4.83
1.5
1.2
—
—
—
0
0
27
107
2.57
4.83
1.8
1.4
95.8
111.8
u/ml
—
9
18
25
96
2.65
4.76
3.0
2.5
—
—
—
0
0
80
484
1.72
4.69
4.6
3.0
2.3
2.1
mmol/l
0.29
63
379
17
53
3.25
4.63
1.4
1.2
—
—
—
0
0
28
116
2.46
4.59
1.5
1.2
185.7
226.6
u/ml
0.57
20
68
47
242
2.00
4.58
1.6
1.9
22.3
21.5
s
0.22
39
219
42
208
2.07
4.55
3.6
2.9
0.6
0.3
g/l
0.39
14
82
29
123
2.40
4.53
2.7
2.5
137.0
129.5
g/l
0.94
22
96
231
1779
1.41
4.52
3.3
3.2
525.3
189.5
mg/l
0.45
142
1096
249
1944
1.39
4.50
3.3
3.0
7.6
7.7
mmol/l
0.20
202
1638
72
430
1.74
4.43
4.1
3.2
4.5
4.6
pmol/l
0.55
64
376
24
94
2.60
4.41
1.2
1.3
—
—
—
0
0
11
26
4.27
4.36
2.9
2.9
—
—
—
0
0
155
1116
1.47
4.35
1.6
1.6
—
—
—
0
0
16
50
3.24
4.35
1.4
1.3
0.4
0.4
g/l
—
9
35
16
50
3.24
4.35
1.4
1.3
2.5
2.7
g/l
—
9
36
15
45
3.37
4.34
1.5
3.4
77.1
110.2
nmol/l
0.67
15
45
77
472
1.69
4.32
5.3
2.8
—
—
—
0
0
28
120
2.38
4.29
5.0
3.1
3.5
2.6
mmol/l
0.80
22
80
638
5796
1.38
4.21
22.7
14.6
13.6
13.6
%
0.40
624
5655
28
122
2.34
4.14
1.9
1.4
—
—
—
0
0
72
440
1.69
4.10
2.3
2.1
12.3
12.8
nmol/l
0.23
66
398
14
42
3.37
4.05
1.7
1.2
—
—
—
0
0
117
808
1.52
4.02
1.3
1.3
—
—
—
0
0
78
490
1.65
4.00
4.7
2.9
5.9
5.8
kpa
0.20
73
474
21
81
2.63
4.00
2.1
1.8
1.7
1.6
mmol/l
0.38
21
81
814
7781
1.78
3.98
28.9
17.6
253.9
253.3
e9/l
0.10
801
7584
814
7785
1.77
3.91
28.7
17.5
91.0
90.7
fl
1.31
808
7669
814
7786
1.77
3.90
28.6
17.5
30.3
30.2
pg
0.70
808
7670
238
1883
1.36
3.89
4.0
3.8
7.5
6.8
mg/mmol
0.09
150
1152
814
7787
1.77
3.88
28.8
17.6
4.5
4.5
e12/l
1.45
797
7568
814
7788
1.77
3.86
28.8
17.6
6.8
6.6
e9/l
0.94
797
7567
45
243
1.90
3.86
6.2
3.1
—
—
—
0
0
21
83
2.57
3.82
1.5
1.2
—
0.8
nmol/l
—
0
6
814
7791
1.76
3.82
29.0
17.7
134.8
135.5
g/l
0.85
809
7676
112
775
1.51
3.81
2.0
1.7
—
—
—
0
0
26
114
2.32
3.81
1.2
1.2
—
—
—
0
0
73
457
1.65
3.81
3.5
2.7
66.5
67.2
g/l
0.45
65
422
106
728
1.52
3.74
1.6
1.4
—
—
—
0
0
106
728
1.52
3.74
8.2
4.9
1.0
1.0
mmol/l
0.56
95
676
42
225
1.91
3.70
2.2
2.1
0.5
1.4
ug/l
1.18
34
200
697
6472
1.40
3.67
20.7
13.0
39.4
39.9
%
0.61
532
4786
21
85
2.51
3.65
1.6
1.2
0.5
0.6
nmol/l
0.46
21
79
196
1518
1.38
3.64
5.3
4.2
—
—
—
0
0
50
287
1.79
3.56
4.8
2.9
—
—
—
0
0
43
236
1.87
3.53
1.4
2.1
1.6
1.5
g/l
0.27
35
206
8
13
6.20
3.50
1.4
1.2
—
—
—
0
0
26
119
2.22
3.47
2.6
1.7
—
—
—
0
0
61
374
1.68
3.46
1.8
2.6
—
—
—
0
0
31
153
2.06
3.44
1.8
1.2
—
—
—
0
0
71
454
1.61
3.43
2.4
2.6
70.0
71.9
e9/l
0.17
53
360
21
88
2.42
3.41
1.5
1.3
—
—
—
0
0
51
299
1.75
3.40
5.3
11.7
24.5
24.5
mmol/l
0.04
46
277
22
96
2.33
3.29
1.4
1.6
0.5
0.8
g/l
1.54
15
75
17
66
2.61
3.23
1.7
1.3
—
—
—
0
0
18
72
2.53
3.22
1.9
1.3
—
—
—
0
0
83
559
1.54
3.22
7.9
2.9
—
—
—
0
0
41
232
1.81
3.09
1.5
1.7
—
—
—
0
0
11
34
3.26
3.06
1.3
1.2
—
—
—
0
0
18
74
2.46
3.06
1.6
1.6
54.2
54.3
%
0.00
13
50
13
45
2.92
3.03
1.2
1.2
—
—
—
0
0
88
609
1.50
3.02
2.5
2.6
1.8
1.8
%
0.04
75
541
219
1772
1.32
3.00
1.7
1.6
1.3
1.4
mmol/l
0.40
186
1513
75
503
1.54
2.98
1.7
1.4
—
—
—
0
0
94
662
1.47
2.96
7.1
9.3
1.3
1.0
mmol/l
0.32
81
520
46
274
1.72
2.93
2.7
2.2
1784.4
2372.6
u/l
0.24
16
109
18
76
2.40
2.91
3.9
2.6
—
—
—
0
0
18
76
2.40
2.91
1.6
1.2
—
—
—
0
0
73
497
1.51
2.72
2.9
2.2
5.8
7.5
ug/l
0.29
61
442
21
99
2.15
2.66
1.1
1.1
0.4
1.0
u/ml
—
10
35
23
113
2.06
2.63
3.1
2.9
—
—
—
0
0
42
252
1.70
2.63
1.1
1.1
—
—
—
0
0
730
6924
1.35
2.61
5.2
4.6
2.7
2.8
mmol/l
1.39
675
6399
24
122
1.99
2.52
4.8
3.4
5.0
4.2
e9/l
0.66
24
122
149
1169
1.33
2.51
2.9
2.9
2.4
2.4
mmol/l
0.69
122
1036
68
466
1.50
2.48
3.4
3.3
110.9
192.5
ng/l
2.65
56
422
33
189
1.78
2.44
1.2
1.1
—
—
—
0
0
25
131
1.94
2.42
2.8
4.3
—
—
—
0
0
24
125
1.95
2.37
5.5
3.7
60.2
57.1
%
0.50
24
125
30
169
1.80
2.35
1.3
1.2
1.4
3.3
u/ml
—
5
20
48
310
1.58
2.29
2.4
2.3
—
—
—
0
0
56
375
1.53
2.29
6.9
6.6
—
—
—
0
0
192
1579
1.28
2.28
5.0
4.2
2.0
2.1
ug/l
0.15
166
1422
8
23
3.50
2.27
9.4
2.3
—
—
—
0
0
21
106
2.01
2.27
1.1
1.1
4.0
10.3
u/ml
1.30
14
52
717
6820
1.30
2.23
4.8
4.2
4.7
4.7
mmol/l
1.19
680
6339
89
658
1.39
2.20
1.4
1.4
—
—
—
0
0
11
42
2.64
2.19
2.5
1.9
398.3
574.8
e6/l
—
6
16
6
14
4.31
2.15
1.8
1.4
—
—
—
0
0
49
324
1.54
2.13
1.4
1.4
36.5
28.9
iu/l
0.66
40
278
20
102
1.98
2.11
6.0
2.5
—
—
—
0
0
74
534
1.42
2.10
1.4
1.4
—
—
—
0
0
29
168
1.75
2.10
2.6
4.0
40.9
79.0
mg/l
0.47
17
131
40
254
1.60
2.07
3.4
2.1
1.1
1.3
%
0.43
40
254
5
10
5.02
2.07
1.4
1.6
—
—
—
0
0
29
169
1.74
2.06
2.6
3.9
38.1
46.9
mg/l
0.17
17
132
49
328
1.52
2.03
9.8
12.9
—
—
—
0
0
15
70
2.16
1.99
1.9
1.7
91.3
89.7
%
0.47
15
70
7
21
3.35
1.97
1.1
1.7
—
—
—
0
0
14
64
2.21
1.95
1.7
1.6
—
—
—
0
0
5
11
4.56
1.94
1.8
2.0
—
—
—
0
0
8
27
2.98
1.94
9.4
2.1
—
—
—
0
0
56
391
1.46
1.91
1.7
1.6
—
—
—
0
0
19
99
1.94
1.91
1.1
1.0
—
—
—
0
0
24
136
1.79
1.89
1.4
1.7
1710.6
14668.8
e6/l
2.14
16
100
12
52
2.33
1.88
2.4
2.1
0.7
1.2
e9/l
—
5
29
15
72
2.10
1.87
1.2
1.5
—
—
—
0
0
15
72
2.10
1.87
1.2
1.5
—
—
—
0
0
15
72
2.10
1.87
1.2
1.5
—
—
—
0
0
15
72
2.10
1.87
1.2
1.5
—
—
—
0
0
19
100
1.92
1.86
1.3
1.2
—
—
—
0
0
18
93
1.96
1.86
2.4
1.7
—
—
—
0
0
41
270
1.54
1.85
1.3
1.6
—
—
—
0
0
29
175
1.68
1.85
1.2
1.1
—
—
—
0
0
20
108
1.87
1.83
1.4
1.2
—
—
—
0
0
7
23
3.06
1.80
1.3
1.2
—
—
—
0
0
41
272
1.53
1.80
1.3
1.7
—
—
—
0
0
41
272
1.53
1.80
1.3
1.7
—
—
—
0
0
38
248
1.56
1.79
3.4
2.1
0.7
0.7
%
0.01
38
239
18
95
1.91
1.76
2.3
1.8
61.6
62.0
%
0.02
18
95
38
249
1.55
1.76
1.3
1.8
—
—
—
0
0
685
6531
1.23
1.75
4.3
3.7
1.3
1.3
mmol/l
0.02
633
6008
41
274
1.52
1.74
1.3
1.7
—
—
—
0
0
9
36
2.52
1.74
2.1
1.2
6.8
6.3
ug/l
—
9
28
5
13
3.86
1.71
4.2
2.8
—
—
—
0
0
5
13
3.86
1.71
8.4
5.7
—
—
—
0
0
21
118
1.80
1.71
1.2
1.1
5.8
1.8
u/ml
—
9
43
15
75
2.02
1.70
1.1
1.0
0.2
0.8
u/ml
—
6
11
10
42
2.40
1.68
2.5
1.9
10.2
10.7
%
—
10
42
7
25
2.81
1.65
1.0
1.6
—
—
—
0
0
73
551
1.35
1.64
5.4
3.8
0.8
0.8
%
0.04
23
157
94
738
1.31
1.62
5.9
7.0
104.0
104.4
mmol/l
0.41
94
710
30
190
1.60
1.62
1.8
1.7
45.7
40.2
nmol/l
0.71
30
184
13
63
2.08
1.60
1.0
1.0
—
—
—
0
0
707
6783
1.23
1.59
4.8
4.1
1.5
1.5
mmol/l
0.49
662
6266
63
468
1.37
1.57
1.4
1.5
—
—
—
0
0
69
521
1.35
1.55
5.6
3.8
0.0
0.1
%
3.09
22
142
67
505
1.35
1.53
5.0
3.7
0.3
0.4
%
0.50
15
109
11
51
2.17
1.51
1.2
1.2
—
—
—
0
0
5
16
3.14
1.44
1.4
1.0
—
—
—
0
0
5
16
3.14
1.44
2.6
1.4
—
—
—
0
0
98
789
1.27
1.41
1.6
1.7
—
—
—
0
0
40
280
1.45
1.40
1.2
1.1
—
—
—
0
0
17
96
1.79
1.39
1.5
1.5
—
—
—
0
0
20
119
1.70
1.38
1.4
1.3
—
—
—
0
0
113
929
1.25
1.37
3.3
2.7
0.6
0.7
ug/l
0.50
69
562
31
207
1.52
1.37
1.4
1.8
—
—
—
0
0
19
112
1.71
1.36
1.5
2.1
—
—
—
0
0
6
24
2.51
1.30
36.0
9.8
—
—
—
0
0
17
99
1.73
1.28
1.1
1.1
—
—
—
0
0
15
84
1.80
1.27
1.2
1.1
1.6
5.3
u/ml
—
6
32
24
154
1.57
1.27
6.6
3.5
—
—
—
0
0
6
25
2.41
1.24
1.0
1.0
145.3
152.2
nmol/l
—
6
25
10
49
2.05
1.22
1.3
1.1
—
—
—
0
0
10
49
2.05
1.22
1.8
2.5
—
—
—
0
0
18
109
1.67
1.19
1.3
1.4
33.9
24.4
u/l
0.50
13
90
12
64
1.89
1.18
2.9
3.9
—
—
—
0
0
10
50
2.01
1.17
1.3
1.3
—
—
—
0
0
35
249
1.42
1.16
1.3
1.3
194.7
229.0
miu/ml
0.31
20
126
5
20
2.51
1.15
1.0
2.0
—
—
—
0
0
233
2585
0.86
1.12
2.8
2.6
—
—
—
0
0
15
88
1.72
1.12
2.1
2.3
—
—
—
0
0
5
21
2.39
1.09
4.0
3.5
—
—
—
0
0
19
121
1.58
1.06
1.2
1.1
—
—
—
0
0
7
33
2.13
1.05
4.0
2.8
—
—
—
0
0
15
90
1.68
1.04
1.3
1.0
2.0
4.2
u/ml
—
6
33
21
138
1.53
1.03
1.2
1.2
—
—
—
0
0
19
122
1.57
1.03
1.2
1.1
—
—
—
0
0
20
131
1.54
1.00
1.8
1.8
170.6
216.7
pmol/l
1.53
20
123
13
76
1.72
0.99
1.5
1.3
32.3
38.9
mu/l
0.18
13
69
11
61
1.81
0.98
1.5
1.2
1.5
1.3
u/ml
—
6
28
61
488
1.27
0.98
5.9
3.9
0.0
0.8
%
0.50
19
116
20
132
1.53
0.97
1.3
1.2
3.6
3.8
mmol/l
0.42
20
125
7
37
1.90
0.94
1.1
1.0
—
—
—
0
0
14
87
1.62
0.88
1.4
2.5
—
—
—
0
0
6
32
1.88
0.82
2.0
2.5
2027.3
1880.2
ml
—
6
27
61
502
1.23
0.80
4.8
3.5
1.2
1.2
mmol/l
0.24
55
439
8
48
1.67
0.79
1.1
1.3
—
—
—
0
0
12
75
1.61
0.75
3.6
2.2
—
—
—
0
0
7
38
1.85
0.73
1.1
1.1
—
—
—
0
0
9
55
1.64
0.73
1.3
1.3
—
—
—
0
0
26
194
1.35
0.72
2.5
1.8
4.1
5.3
iu/l
0.33
11
68
12
76
1.59
0.72
3.6
2.3
105.8
106.0
mmol/l
0.03
12
76
12
76
1.59
0.72
3.6
2.3
4.0
4.0
mmol/l
0.07
12
76
20
143
1.41
0.70
14.7
11.0
105.6
105.2
mmol/l
0.15
20
129
20
143
1.41
0.70
14.7
11.0
10.5
11.3
mmol/l
0.89
20
129
7
41
1.71
0.70
1.1
1.4
0.8
1.2
promille
—
7
32
9
59
1.53
0.68
1.0
1.2
—
—
—
0
0
15
103
1.46
0.65
1.7
1.5
—
—
—
0
0
7
44
1.60
0.65
1.3
1.2
—
—
—
0
0
5
29
1.73
0.64
1.6
1.5
—
—
—
0
0
24
182
1.33
0.62
1.1
1.1
—
—
—
0
0
15
106
1.42
0.58
1.1
1.1
—
—
—
0
0
31
247
1.26
0.57
10.7
7.8
1.0
1.0
%
0.02
31
231
24
185
1.31
0.56
3.6
3.0
—
—
—
0
0
17
229
0.74
0.56
18.6
9.2
—
—
—
0
0
11
74
1.49
0.53
1.0
1.2
—
—
—
0
0
9
62
1.46
0.53
1.4
1.1
368.4
402.2
nmol/l
—
9
52
66
755
0.86
0.52
1.4
1.4
—
—
—
0
0
23
181
1.28
0.48
1.4
1.3
—
—
—
0
0
16
119
1.35
0.48
1.3
1.3
2.3
4.2
u/ml
—
7
41
14
187
0.74
0.46
1.4
1.5
—
—
—
0
0
10
69
1.45
0.44
1.7
1.9
32.4
32.6
pg
—
10
69
32
267
1.21
0.42
1.2
1.2
—
—
—
0
0
17
131
1.30
0.42
7.6
3.5
26.8
26.9
mg/l
—
10
85
14
184
0.76
0.42
1.4
1.4
—
—
—
0
0
5
34
1.47
0.40
4.8
6.1
—
—
—
0
0
14
182
0.77
0.39
1.4
1.4
—
—
—
0
0
71
639
1.12
0.38
3.4
4.2
3.1
27.8
ug/l
1.25
58
512
8
114
0.70
0.37
1.6
1.6
—
—
—
0
0
207
1962
1.07
0.37
1.6
1.5
—
—
—
0
0
6
43
1.40
0.35
1.0
1.3
—
—
—
0
0
11
82
1.35
0.34
2.6
2.3
—
—
—
0
0
22
182
1.21
0.33
1.6
2.5
—
—
—
0
0
6
47
1.28
0.32
1.8
1.7
7.2
6.5
mmol/l
—
6
33
7
52
1.35
0.31
1.1
1.1
73.9
35.6
mg/l
—
7
39
7
55
1.27
0.30
1.4
1.3
—
—
—
0
0
7
56
1.25
0.29
3.3
3.7
—
—
—
0
0
8
62
1.29
0.28
1.0
1.1
—
—
—
0
0
5
38
1.32
0.23
2.2
4.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
26
229
1.14
0.22
4.7
4.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
15
126
1.19
0.21
1.5
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
6
48
1.25
0.20
2.0
2.8
—
—
—
0
0
6
52
1.15
0.19
1.8
1.6
—
—
—
0
0
15
128
1.17
0.18
2.6
2.4
197.1
55.7
ug/min
—
9
72
15
130
1.16
0.15
4.2
2.1
1.3
0.8
nmol/l
—
10
110
7
87
0.80
0.14
1.0
1.2
—
—
—
0
0
10
84
1.19
0.14
1.4
1.3
—
—
—
0
0
50
472
1.06
0.13
1.3
1.4
—
—
—
0
0
42
395
1.07
0.12
1.7
3.2
28.5
53.8
u/ml
1.44
42
383
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
63
0.79
0.08
1.2
1.3
6.5
6.9
mmol/l
—
5
58
7
67
1.05
0.08
2.6
2.5
—
—
—
0
0
8
74
1.08
0.07
1.0
1.1
—
—
—
0
0
5
49
1.02
0.00
2.0
1.5
—
—
—
0
0
5
53
0.94
0.00
1.8
1.5
1.0
1.0
g/l
—
5
53
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
13.7
—
0
7
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
16.8
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
38.4
—
0
7
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.0
1.2
—
—
—
0
0
7
72
0.97
0.00
1.6
1.3
37.8
32.9
g/l
—
7
65
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
191.6
—
0
5

Mortality – FinRegistry

Association

Association between endpoint N14_URETHRITISANDURSYNDR and mortality.

Females

Parameter HR [95% CI] p-value
N14_URETHRITISANDURSYNDR 1.345 [1.17, 1.54] < 0.001
Birth year 0.997 [0.99, 1.01] 0.536

During the follow-up period (1.1.1998 — 31.12.2019), 608 out of 3107 females with N14_URETHRITISANDURSYNDR died.

Males

Parameter HR [95% CI] p-value
N14_URETHRITISANDURSYNDR 1.552 [1.27, 1.89] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 327 out of 1942 males with N14_URETHRITISANDURSYNDR died.

Mortality risk

Mortality risk for people of age

years, who have N14_URETHRITISANDURSYNDR.

N-year risk Females Males
1 0.172% 0.323%
5 0.933% 1.761%
10 2.163% 4.378%
15 4.029% 8.145%
20 7.197% 14.021%

Relationships between endpoints

Index endpoint: N14_URETHRITISANDURSYNDR – Urethritis and urethral syndrome

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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