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Benign neoplasm: Lip

DOID Endpoint Browser PheWeb

CD2_BENIGN_LIP

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D10.0
  • Hospital discharge: ICD-9 — 2100
  • Hospital discharge: ICD-8 — 2100
  • Cause of death: ICD-10 — D10.0
  • Cause of death: ICD-9 — 2100
  • Cause of death: ICD-8 — 2100

2 out of 7 registries used, show all original rules.

776

4. Check minimum number of events

None

776

5. Include endpoints

None

776

6. Filter based on genotype QC (FinnGen only)

776

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum labii (oris)

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5939 2865 3040
Only index persons 5167 2575 2592
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.10 0.09 0.10
Median age at first event (years)
Whole population 56.86 56.25 57.39
Only index persons 55.08 55.45 54.71

-FinnGen-

Key figures

All Female Male
Number of individuals 776 391 385
Unadjusted period prevalence (%) 0.15 0.13 0.17
Median age at first event (years) 59.23 55.57 62.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
710
Matched controls
7099
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.09
ICD-10 Finland
Benign tumor of the lip UNS
3362.3
269.5
243
*
EAA10
NOMESCO Finland
Excision of lesion of lip
215.1
213.4
212
14
D10.04
ICD-10 Finland
Lower lip tumor in the lower lip mucosa
+∞
196.2
179
*
D10.00
ICD-10 Finland
Upper lip tumor in upper lip on lip lip border
+∞
114.8
107
*
D10.01
ICD-10 Finland
Uper lip tumor in the upper lip mucosa
+∞
64.6
61
*
TEA00
NOMESCO Finland
Biopsy of lip
34.5
61.5
80
26
D10.03
ICD-10 Finland
Lower lip tumor in the lower lip at the lip red border
+∞
52.8
50
*
D10.0
ICD-10 Finland
Benign neoplasm: Lip
386.6
37.4
37
*
21000
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Lip
+∞
34.7
33
*
8070/3-C00.1
ICD-O-3
Squamous cell carcinoma, NOS, of external lower lip
107.9
28.9
31
*
2100A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Lip
+∞
28.3
27
*
C00.1
ICD-10 Finland
Malignant neoplasm: External lower lip
237.3
22.7
23
*
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
82.8
21.8
24
*
EAA30
NOMESCO Finland
Partial excision of lower lip
108.0
19.7
21
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.3
18.0
97
326
D10.05
ICD-10 Finland
Lower lip tumor in lower lip mucosa and on lip lip border
+∞
15.7
15
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.5
15.4
40
65
4381
FHL
Exemption of local change
46.0
15.1
18
*
D20
ICPC
Mouth/tongue/lip symptom/complaint
3.8
10.5
44
122
K11.69
ICD-10 Finland
Mukocele UNS
33.0
10.4
13
*
D18.0
ICD-10 Finland
Haemangioma, any site
5.0
9.7
30
62
C00.9
ICD-10 Finland
Malignant neoplasm: Lip, unspecified
101.3
9.4
10
*
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
4.5
9.0
31
72
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.0
9.0
51
177
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
8.2
157
965
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.8
8.1
33
90
D23.0
ICD-10 Finland
Benign neoplasm: Skin of lip
17.4
8.1
12
7
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
8.1
127
733
D83
ICPC
Mouth/tongue/lip disease
13.2
7.9
13
10
R01AD09
ATC
mometasone; nasal
1.6
7.5
278
2058
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.3
6.9
32
99
K13.03
ICD-10 Finland
Keilit UNS
16.9
6.8
10
6
SXA10
NOMESCO Finland
Epithel biopsy of mouth
6.0
6.6
17
29
J01DB01
ATC
cefalexin; oral
1.6
6.5
541
4755
SPAT1153
SPAT
Removal of sutures
1.6
6.4
219
1576
N05CF01
ATC
zopiclone; oral
1.6
6.3
217
1562
EKB00
NOMESCO Finland
Excision of lesion of cheek
11.1
6.3
11
10
L57.0
ICD-10 Finland
Actinic keratosis
2.0
6.3
76
395
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
6.0
439
3707

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
384
2483
2.08
21.92
2.5
2.1
—
—
—
0
0
117
648
1.95
9.22
4.0
4.4
—
—
—
0
0
515
4364
1.54
7.17
4.7
4.4
—
—
—
0
0
366
2907
1.49
6.85
5.2
5.8
1.2
1.2
mmol/l
0.26
305
2611
277
2089
1.51
6.62
5.8
5.5
—
—
—
0
0
391
3179
1.46
6.32
5.9
6.6
1.2
1.2
mmol/l
0.02
323
2674
557
4869
1.51
6.12
7.9
7.6
79.4
79.3
u/l
0.01
518
4562
391
3206
1.44
5.89
5.8
5.9
0.2
0.2
e9/l
0.02
333
2817
254
1934
1.47
5.60
4.3
4.0
—
—
—
0
0
129
864
1.59
5.15
24.8
25.4
1.3
1.3
inr
0.01
18
117
53
276
1.99
5.00
1.2
1.3
—
—
—
0
0
372
3081
1.40
5.00
5.6
5.6
0.6
0.6
e9/l
0.40
318
2665
354
2911
1.40
4.95
5.7
5.7
2.8
2.9
%
0.18
321
2720
380
3163
1.39
4.94
5.7
5.7
1.8
1.9
e9/l
0.18
330
2774
345
2827
1.40
4.91
5.9
5.7
0.6
0.7
%
1.19
311
2647
373
3097
1.39
4.91
5.7
5.6
0.0
0.0
e9/l
2.01
322
2684
328
2680
1.39
4.69
2.2
2.0
94.7
94.6
pmol/l
0.01
158
1384
353
2922
1.38
4.65
6.2
6.0
8.6
8.8
%
0.45
321
2748
527
4660
1.41
4.65
4.9
4.2
12.9
12.7
mm/h
0.11
464
4270
359
2984
1.38
4.59
6.0
5.9
27.7
27.2
%
0.43
321
2786
609
5540
1.46
4.48
18.2
16.0
39.8
39.7
%
0.09
388
3823
354
2945
1.37
4.47
5.6
5.6
57.5
57.7
%
0.07
321
2766
438
3770
1.37
4.46
4.6
4.7
6.9
6.7
mmol/l
0.55
409
3540
18
60
3.05
4.42
1.6
1.5
13.9
29.1
u/l
1.26
11
48
421
3613
1.36
4.30
8.8
9.1
3.9
4.1
e9/l
1.66
365
3181
14
41
3.46
4.20
2.6
1.4
—
—
—
0
0
272
2186
1.38
4.19
3.0
3.4
2.4
2.4
mmol/l
0.27
220
1900
69
419
1.71
4.04
3.0
2.8
3.9
4.0
e9/l
0.19
36
321
84
545
1.61
3.83
1.4
1.4
—
—
—
0
0
13
39
3.37
3.77
3.3
2.1
—
—
—
0
0
614
5652
1.41
3.73
5.5
4.7
1.9
2.1
mu/l
0.60
535
5115
200
1560
1.38
3.63
2.5
2.3
—
—
—
0
0
659
6165
1.46
3.47
17.1
15.0
22.7
24.7
mg/l
0.96
543
4963
82
543
1.57
3.44
3.0
3.0
122.6
212.0
ng/l
3.70
71
495
18
70
2.61
3.40
1.9
1.5
41.1
65.7
%
1.62
13
51
646
6044
1.41
3.19
5.1
4.7
6.0
6.0
mmol/l
0.05
558
5472
248
2036
1.32
3.16
2.6
2.4
—
—
—
0
0
111
800
1.45
3.13
1.3
1.3
—
—
—
0
0
52
322
1.66
2.89
3.5
3.7
—
—
—
0
0
626
5861
1.35
2.79
4.3
4.0
1.3
1.3
mmol/l
0.19
537
5321
342
2973
1.27
2.71
4.0
4.0
—
—
—
0
0
661
6249
1.39
2.71
5.4
5.0
2.7
2.7
mmol/l
0.24
575
5706
160
1258
1.34
2.71
1.9
1.8
1086.8
1180.8
nmol/l
0.53
100
946
678
6440
1.42
2.68
19.8
17.6
4.0
4.0
mmol/l
1.53
651
6264
66
442
1.54
2.68
1.2
1.2
—
—
—
0
0
62
410
1.56
2.66
2.7
3.0
—
—
—
0
0
202
1647
1.31
2.65
2.4
2.2
2.9
3.1
mg/l
0.59
156
1389
676
6422
1.41
2.63
19.7
17.4
139.7
139.7
mmol/l
0.02
652
6252
67
454
1.52
2.58
1.4
1.4
—
—
—
0
0
648
6120
1.36
2.56
4.9
4.5
4.6
4.6
mmol/l
0.56
570
5625
310
2681
1.26
2.52
8.3
9.6
1.2
1.3
inr
0.26
61
762
235
1969
1.28
2.48
2.3
2.1
179.3
266.6
u/l
1.15
213
1853
99
732
1.40
2.45
2.7
2.8
7.7
8.7
umol/l
0.18
88
655
116
881
1.37
2.45
1.1
1.2
—
—
—
0
0
43
270
1.63
2.31
3.5
4.1
25.0
25.1
mmol/l
0.06
35
255
688
6584
1.40
2.29
12.1
10.7
27.8
26.1
u/l
0.68
657
6338
642
6080
1.32
2.29
5.0
4.5
1.4
1.5
mmol/l
0.49
561
5553
37
224
1.68
2.28
1.0
1.1
—
—
—
0
0
173
2091
0.78
2.23
3.1
3.0
—
—
—
0
0
80
580
1.42
2.22
2.7
2.5
5.8
6.8
ug/l
0.27
63
512
506
4664
1.24
2.20
4.4
3.9
14.9
14.8
pmol/l
0.07
424
4200
161
1307
1.29
2.16
1.2
1.2
2.4
1.4
u/ml
0.34
31
347
710
6845
1.44
2.13
25.3
21.9
91.1
91.2
fl
0.43
695
6728
376
3369
1.23
2.11
6.2
6.2
11.9
11.3
umol/l
0.29
350
3202
710
6847
1.43
2.11
25.4
22.0
6.9
6.7
e9/l
0.31
686
6645
710
6847
1.43
2.11
25.4
22.0
4.5
4.5
e12/l
0.04
686
6647
710
6849
1.43
2.08
25.5
22.1
134.5
134.9
g/l
0.29
695
6728
611
5770
1.28
2.08
6.4
6.1
40.3
40.1
mmol/mol
0.22
535
5311
235
2012
1.24
2.01
2.6
2.4
60.2
56.5
u/l
0.76
210
1857
316
2793
1.22
1.99
4.7
4.7
35.5
35.3
g/l
0.30
286
2598
709
6846
1.41
1.98
25.3
21.9
30.3
30.4
pg
0.29
695
6727
193
1622
1.25
1.94
1.7
1.6
21.6
20.6
nmol/l
0.31
149
1361
6
16
3.77
1.94
2.5
1.1
0.6
2.8
mmol/l
—
6
16
82
613
1.38
1.93
3.8
3.7
—
—
—
0
0
8
28
2.88
1.86
1.0
1.0
—
0.2
—
0
6
48
327
1.50
1.86
2.6
3.8
—
—
—
0
0
11
46
2.41
1.86
3.5
2.7
—
—
—
0
0
91
701
1.34
1.79
2.6
4.3
4.4
25.2
ug/l
1.16
67
590
24
139
1.75
1.77
2.5
2.2
—
—
—
0
0
61
441
1.42
1.76
3.9
3.5
4.9
5.1
kpa
1.40
54
408
707
6843
1.37
1.75
25.4
22.0
248.4
246.2
e9/l
0.38
688
6661
79
598
1.36
1.74
3.5
3.6
2.3
1.9
mmol/l
0.44
63
483
13
61
2.15
1.72
1.5
1.3
4224.3
309760.7
e6/l
—
8
40
5
13
3.86
1.71
4.2
2.3
0.8
1.1
ug/l
—
5
13
188
1597
1.23
1.71
4.0
3.9
91.9
89.1
%
0.77
179
1562
668
6419
1.29
1.70
16.4
14.1
—
—
—
0
0
39
260
1.53
1.69
2.1
1.9
—
—
—
0
0
225
1951
1.22
1.67
3.4
3.2
—
—
—
0
0
72
543
1.36
1.63
3.6
3.0
66.5
66.7
g/l
0.10
56
489
141
1166
1.26
1.63
1.5
1.5
2.4
2.5
g/l
0.21
78
712
213
1842
1.22
1.62
3.8
4.1
—
—
—
0
0
5
14
3.59
1.61
1.0
1.0
—
—
—
0
0
258
2278
1.20
1.58
5.5
5.0
4.1
2.8
ug/l
0.37
220
2028
20
114
1.77
1.57
2.4
1.8
187.9
222.1
pmol/l
0.65
20
107
76
582
1.34
1.57
1.4
1.4
—
—
—
0
0
281
2505
1.19
1.54
4.2
3.8
43.0
53.4
ng/l
0.25
207
1814
46
327
1.43
1.48
2.4
2.4
—
—
—
0
0
228
2002
1.20
1.47
3.1
3.1
1420.2
1414.9
ng/l
0.01
189
1717
73
562
1.33
1.47
4.5
2.5
75.0
69.7
e9/l
0.65
56
434
296
2660
1.18
1.47
3.1
2.7
144.1
130.2
ug/l
0.23
258
2429
160
1360
1.22
1.44
1.9
1.7
430.9
4513066.9
pmol/l
0.50
116
1108
24
149
1.63
1.42
1.7
1.6
339.7
298.5
mu/l
0.24
24
136
13
67
1.96
1.39
1.7
2.8
—
—
—
0
0
12
60
2.02
1.38
2.7
1.3
—
—
—
0
0
103
838
1.26
1.38
4.7
5.4
1.0
1.0
mmol/l
1.06
86
770
43
307
1.42
1.37
1.4
1.9
1.4
1.5
g/l
0.43
35
268
9
41
2.21
1.37
1.2
1.0
—
—
—
0
0
53
393
1.37
1.37
1.2
1.2
—
—
—
0
0
61
463
1.34
1.36
2.5
2.6
—
—
—
0
0
5
17
2.95
1.36
5.2
2.6
—
—
—
0
0
115
951
1.25
1.35
2.4
2.3
2.3
2.3
g/l
0.05
102
878
67
517
1.32
1.34
6.3
8.1
—
—
—
0
0
72
562
1.31
1.33
2.9
1.9
360.6
375.0
nmol/l
0.24
65
517
0
40
0.00
1.33
0.0
1.2
—
—
—
0
0
216
1904
1.19
1.33
3.3
3.9
7.4
7.4
ph
0.08
28
361
20
121
1.67
1.32
1.8
1.5
—
—
—
0
0
0
41
0.00
1.31
0.0
1.7
—
9.1
—
0
36
224
1989
1.18
1.26
3.0
3.1
7.3
7.6
mmol/l
0.30
171
1637
249
2760
0.86
1.24
9.3
9.4
0.0
0.0
e9/l
0.33
202
2258
95
777
1.25
1.23
1.7
1.4
—
—
—
0
0
180
1573
1.19
1.22
5.5
6.6
—
—
—
0
0
5
19
2.64
1.21
5.4
2.3
—
—
—
0
0
13
71
1.85
1.20
1.2
1.3
—
—
—
0
0
25
165
1.53
1.19
1.8
1.6
7178.4
16949.8
e6/l
1.14
18
119
31
215
1.46
1.17
1.8
2.4
36.9
37.9
g/l
0.30
17
181
10
50
2.01
1.17
1.8
1.3
39.6
28.5
%
—
5
34
107
896
1.23
1.13
2.5
2.4
22.6
22.6
%
0.01
86
770
145
1251
1.20
1.13
2.7
3.1
2.5
2.4
mmol/l
0.36
128
1100
14
80
1.76
1.13
1.0
1.2
—
—
—
0
0
111
935
1.22
1.11
2.2
2.0
—
—
—
0
0
7
31
2.27
1.10
7.1
6.3
—
—
—
0
0
91
752
1.24
1.10
2.1
1.7
—
—
—
0
0
85
699
1.24
1.07
2.6
2.2
97.5
129.2
ug/g
0.95
59
543
5
22
2.28
1.03
2.6
2.8
—
—
—
0
0
331
3069
1.14
1.00
3.2
3.8
0.0
0.0
estimate
0.00
40
572
67
541
1.26
1.00
2.7
3.5
—
—
—
0
0
86
715
1.23
0.99
1.4
1.3
—
—
—
0
0
142
1240
1.18
0.98
5.4
3.9
61.6
298.5
ng/l
4.28
112
991
121
1043
1.19
0.97
3.0
3.0
3.4
2.2
e6/l
0.69
59
589
153
1346
1.17
0.97
1.7
1.7
1.1
1.2
mg/l
0.22
113
1040
6
119
0.50
0.94
1.3
1.4
—
—
—
0
0
6
27
2.23
0.93
11.2
17.7
—
—
—
0
0
97
824
1.20
0.92
1.4
1.3
946.7
485.0
titre
0.72
21
183
6
28
2.15
0.91
1.0
1.1
—
0.2
—
0
10
14
86
1.64
0.91
1.0
1.2
0.6
0.6
nmol/l
0.15
14
78
44
341
1.31
0.91
6.4
9.1
—
—
—
0
0
26
185
1.42
0.90
1.6
1.5
254.9
282.3
ug/g
0.30
15
112
334
3118
1.13
0.88
3.3
3.8
0.0
0.0
estimate
0.50
40
554
41
317
1.31
0.87
1.4
1.3
—
—
—
0
0
161
1435
1.15
0.86
3.3
3.8
—
—
—
0
0
210
1908
1.14
0.86
3.2
3.2
289.7
231.7
mg/l
0.10
135
1216
330
3083
1.12
0.86
4.6
5.2
0.0
0.0
estimate
0.00
43
572
15
96
1.57
0.85
2.6
3.1
2.5
1.4
%
—
8
80
6
31
1.94
0.84
1.5
1.5
—
—
—
0
0
56
454
1.25
0.83
3.1
2.1
11.3
13.0
nmol/l
0.67
46
400
74
619
1.22
0.83
1.5
1.5
—
—
—
0
0
42
329
1.29
0.82
2.5
3.3
25.7
25.1
mmol/l
0.53
42
321
184
1665
1.14
0.80
2.8
2.8
6553.4
7178.8
umol/l
0.06
148
1429
0
25
0.00
0.79
0.0
1.1
—
37.4
—
0
5
0
25
0.00
0.79
0.0
2.3
—
4713.4
—
0
14
8
48
1.67
0.79
1.1
1.1
—
—
—
0
0
118
1037
1.16
0.77
2.5
2.4
13.0
12.8
umol/l
0.09
103
955
0
28
0.00
0.76
0.0
2.4
—
365.3
—
0
22
9
53
1.71
0.75
1.3
1.4
—
—
—
0
0
9
54
1.67
0.74
2.2
2.4
—
—
—
0
0
5
24
2.09
0.74
2.6
3.4
28.6
33.4
umol/l
—
5
19
196
1791
1.13
0.73
3.5
3.2
0.3
0.5
e6/l
0.51
142
1368
189
1725
1.13
0.72
3.5
3.2
—
—
—
0
0
48
391
1.24
0.71
1.3
1.4
—
—
—
0
0
35
274
1.29
0.71
3.1
3.4
459.7
1181.2
u/ml
0.53
28
234
245
2273
1.11
0.70
4.0
3.9
55.2
137.5
e6/l
1.36
166
1639
150
1658
0.88
0.70
3.7
4.1
0.0
0.0
estimate
0.69
39
556
20
144
1.40
0.68
1.6
1.3
—
—
—
0
0
88
765
1.17
0.67
3.1
2.5
2.1
1.8
%
1.60
70
687
218
2018
1.11
0.65
3.8
3.9
18.9
9.3
mg/mmol
0.48
130
1265
7
44
1.60
0.65
2.9
1.7
13.0
10.3
%
—
7
44
19
137
1.40
0.65
5.1
4.1
1.5
2.8
mmol/l
—
10
94
5
29
1.73
0.64
3.0
2.4
40.0
47.0
umol/l
—
5
22
16
112
1.44
0.64
3.4
2.0
69.5
59.9
%
1.33
16
112
99
874
1.15
0.63
1.7
1.8
—
—
—
0
0
44
532
0.82
0.62
3.7
3.9
—
—
—
0
0
150
1363
1.12
0.62
2.8
2.6
3.9
5.4
e6/l
1.17
131
1204
0
20
0.00
0.60
0.0
1.2
—
17.1
—
0
13
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
4.5
—
0
17
0
23
0.00
0.58
0.0
2.1
—
—
—
0
0
14
98
1.44
0.57
1.3
1.3
—
—
—
0
0
116
1045
1.13
0.56
3.8
3.2
0.8
0.8
mmol/l
0.33
103
973
35
284
1.24
0.56
3.5
3.5
14.5
67.2
u/ml
2.32
35
270
6
37
1.63
0.55
2.0
1.8
—
—
—
0
0
26
205
1.28
0.53
1.8
2.0
21.1
21.3
s
0.08
20
184
57
491
1.17
0.52
3.3
4.0
76.9
86.7
ng/l
0.62
45
438
13
92
1.42
0.50
1.8
2.8
—
—
—
0
0
39
464
0.83
0.50
3.5
4.3
0.0
0.8
%
—
10
122
209
1962
1.09
0.47
3.6
3.3
63.2
109.7
e6/l
0.56
158
1530
85
763
1.13
0.45
5.4
6.9
1.4
1.4
mmol/l
0.01
65
599
11
152
0.72
0.44
3.0
3.9
31.2
27.7
mg/l
—
6
95
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
8
56
1.43
0.42
1.4
1.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
11
79
1.40
0.41
1.5
1.1
—
—
—
0
0
46
528
0.86
0.41
3.6
3.5
1.2
1.2
mmol/l
1.01
40
456
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
2.4
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
8
60
1.34
0.40
1.0
1.1
—
—
—
0
0
8
61
1.31
0.39
1.3
1.2
—
—
—
0
0
14
106
1.33
0.39
1.3
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
22
180
1.23
0.36
2.2
4.9
—
—
—
0
0
16
201
0.79
0.36
10.9
9.6
—
—
—
0
0
84
767
1.11
0.36
5.5
6.8
5.1
5.1
kpa
0.04
77
730
84
768
1.11
0.35
5.5
6.8
12.4
12.1
kpa
0.30
77
734
146
1370
1.08
0.35
3.5
4.1
1.0
1.0
kg/l
0.21
30
191
14
109
1.29
0.33
1.6
1.6
—
—
—
0
0
10
74
1.36
0.32
1.1
1.1
0.7
1.3
u/ml
—
5
25
18
146
1.24
0.32
1.8
1.7
—
—
—
0
0
17
137
1.25
0.32
1.1
1.2
—
—
—
0
0
137
1288
1.08
0.32
2.8
2.8
538.4
556.7
mosm/kgh2o
0.47
110
1100
105
977
1.09
0.31
1.3
1.3
6.3
12.1
u/ml
0.56
35
369
69
629
1.11
0.31
1.8
1.6
—
—
—
0
0
496
5061
0.94
0.31
20.4
18.3
13.7
13.7
%
0.04
490
4958
45
400
1.13
0.31
2.8
2.5
—
19.0
—
0
16
7
53
1.32
0.31
1.1
1.1
—
—
—
0
0
7
55
1.28
0.30
1.1
1.1
—
—
—
0
0
41
461
0.88
0.29
1.5
1.4
—
—
—
0
0
17
139
1.23
0.29
3.1
2.6
—
—
—
0
0
15
121
1.24
0.28
2.7
2.4
—
—
—
0
0
14
112
1.25
0.28
1.1
1.6
—
—
—
0
0
18
215
0.83
0.27
1.1
1.1
—
—
—
0
0
14
113
1.24
0.26
1.1
1.2
—
—
—
0
0
141
1338
1.07
0.26
4.9
4.7
—
—
—
0
0
5
73
0.68
0.26
2.2
1.2
—
—
—
0
0
125
1320
0.94
0.25
3.3
3.0
0.8
0.8
ug/l
0.10
71
877
9
73
1.24
0.25
1.7
2.5
—
—
—
0
0
9
74
1.22
0.25
2.7
3.5
—
—
—
0
0
9
76
1.19
0.24
1.0
1.2
—
—
nmol/l
—
0
0
23
265
0.86
0.24
1.1
1.1
—
28.5
—
0
6
32
285
1.13
0.23
3.2
2.8
—
—
—
0
0
436
4442
0.96
0.22
4.2
3.9
—
—
—
0
0
42
381
1.11
0.22
1.6
1.6
—
—
—
0
0
10
79
1.27
0.22
1.6
1.2
—
—
—
0
0
22
191
1.16
0.22
3.0
3.2
—
—
—
0
0
0
11
0.00
0.21
0.0
7.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
7.2
—
—
—
0
0
22
251
0.87
0.21
1.9
1.7
—
—
—
0
0
161
1675
0.95
0.21
1.8
1.6
1.3
1.4
mmol/l
0.42
130
1400
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
162
1684
0.95
0.20
3.0
3.5
—
—
—
0
0
6
48
1.25
0.20
1.2
1.1
—
2.4
—
0
9
0
14
0.00
0.20
0.0
1.6
—
1.2
—
0
14
0
14
0.00
0.20
0.0
1.5
—
34.7
—
0
8
0
14
0.00
0.20
0.0
1.9
—
18.2
—
0
14
109
1037
1.06
0.20
1.3
1.3
18.1
37.5
iu/ml
3.91
34
324
6
49
1.23
0.20
1.2
1.2
—
—
—
0
0
9
115
0.78
0.20
4.6
3.7
54.0
57.7
%
—
9
115
78
734
1.07
0.20
1.6
1.6
—
—
—
0
0
6
52
1.16
0.19
1.0
1.0
—
—
—
0
0
10
81
1.24
0.19
1.0
1.1
—
—
—
0
0
28
310
0.90
0.18
1.7
1.4
—
—
—
0
0
7
62
1.13
0.17
1.6
3.0
—
—
—
0
0
5
66
0.76
0.17
1.4
1.6
—
—
—
0
0
6
77
0.78
0.15
1.3
1.6
—
—
—
0
0
9
80
1.13
0.15
1.3
1.3
11.1
49.6
mu/l
—
9
72
9
81
1.11
0.15
1.4
1.5
—
—
—
0
0
9
81
1.11
0.15
1.4
1.5
—
—
—
0
0
9
81
1.11
0.15
1.4
1.5
—
—
—
0
0
9
81
1.11
0.15
1.4
1.5
—
—
—
0
0
9
82
1.10
0.15
1.0
1.1
—
—
—
0
0
10
84
1.19
0.14
1.0
1.4
33.3
32.1
g/l
—
10
75
8
99
0.81
0.13
2.6
2.6
—
—
—
0
0
19
170
1.12
0.13
5.1
3.9
7.4
7.4
ph
0.37
19
136
45
479
0.94
0.13
1.4
1.4
—
—
—
0
0
17
151
1.13
0.13
3.8
3.4
0.8
0.9
nmol/l
0.33
12
121
17
151
1.13
0.13
1.5
1.3
205.9
241.4
miu/ml
—
7
75
14
159
0.88
0.13
1.2
1.3
—
—
—
0
0
9
108
0.83
0.13
1.1
1.2
—
—
—
0
0
9
110
0.82
0.13
4.2
3.3
2.6
4.3
e9/l
—
9
110
14
158
0.88
0.12
1.5
1.8
—
—
—
0
0
36
337
1.07
0.11
4.8
3.3
4.5
4.6
pmol/l
0.17
28
291
30
280
1.07
0.10
2.0
1.8
0.9
2.6
ug/l
0.97
22
248
11
96
1.15
0.10
1.3
1.0
—
—
—
0
0
24
223
1.08
0.09
1.5
1.6
—
—
—
0
0
6
54
1.11
0.09
1.3
1.2
—
—
—
0
0
6
56
1.07
0.08
2.7
1.9
—
1.7
—
0
5
6
57
1.05
0.08
1.0
1.4
—
—
—
0
0
7
66
1.06
0.08
1.7
2.5
—
—
—
0
0
11
98
1.12
0.07
1.3
1.1
—
—
—
0
0
6
71
0.84
0.07
1.8
2.2
—
—
—
0
0
8
74
1.08
0.07
1.0
1.2
—
—
—
0
0
9
84
1.07
0.07
3.0
2.7
—
—
—
0
0
44
458
0.96
0.07
4.1
4.4
—
—
—
0
0
9
105
0.86
0.06
1.6
2.9
—
—
—
0
0
48
497
0.96
0.06
3.4
4.3
0.1
0.1
%
0.03
15
144
17
158
1.08
0.06
1.1
1.2
—
—
—
0
0
38
394
0.96
0.05
1.2
1.2
180.5
126.6
iu/ml
—
8
157
51
525
0.97
0.05
3.4
4.2
1.1
1.0
%
0.15
16
160
17
180
0.94
0.04
1.3
1.2
—
—
—
0
0
16
151
1.06
0.03
3.4
4.3
—
—
—
0
0
15
159
0.94
0.03
1.5
1.6
—
—
—
0
0
15
159
0.94
0.03
1.5
1.8
—
—
—
0
0
10
108
0.92
0.03
1.3
1.1
—
—
—
0
0
13
122
1.07
0.02
1.5
2.0
—
—
—
0
0
15
158
0.95
0.02
1.5
1.8
—
—
—
0
0
25
242
1.03
0.02
2.2
3.2
0.6
0.2
g/l
—
10
94
10
107
0.93
0.02
1.1
1.4
—
—
—
0
0
14
133
1.05
0.01
6.9
3.2
—
—
—
0
0
25
257
0.97
0.01
1.0
1.1
—
—
—
0
0
17
176
0.97
0.00
2.2
2.4
51.9
91.9
ug/min
—
9
104
25
256
0.98
0.00
4.7
4.5
—
—
—
0
0
161
1616
1.00
0.00
1.3
1.4
—
—
—
0
0
15
147
1.02
0.00
1.5
1.9
—
—
—
0
0
15
152
0.99
0.00
1.0
1.1
—
—
—
0
0
47
471
1.00
0.00
3.1
4.2
0.6
0.4
%
—
9
116
0
5
0.00
0.00
0.0
1.6
—
330.6
—
0
5
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
0.00
1.2
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.2
1.1
—
—
—
0
0
6
63
0.95
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
8
79
1.01
0.00
1.3
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
18.1
—
0
7
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.0
1.3
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_LIP and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_LIP 1.028 [0.9, 1.17] 0.68
Birth year 0.996 [0.99, 1.0] 0.394

During the follow-up period (1.1.1998 — 31.12.2019), 393 out of 2264 females with CD2_BENIGN_LIP died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_LIP 1.101 [0.97, 1.24] 0.126
Birth year 0.988 [0.98, 1.0] 0.021

During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 2302 males with CD2_BENIGN_LIP died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_LIP.

N-year risk Females Males
1 0.092% 0.172%
5 0.595% 1.164%
10 1.653% 3.209%
15 3.195% 6.197%
20 5.499% 10.545%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_LIP – Benign neoplasm: Lip

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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