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Benign neoplasm: Lip

DOID Endpoint Browser PheWeb

CD2_BENIGN_LIP

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D10.0
  • Hospital discharge: ICD-9 — 2100
  • Hospital discharge: ICD-8 — 2100
  • Cause of death: ICD-10 — D10.0
  • Cause of death: ICD-9 — 2100
  • Cause of death: ICD-8 — 2100

2 out of 7 registries used, show all original rules.

800

4. Check minimum number of events

None

800

5. Include endpoints

None

800

6. Filter based on genotype QC (FinnGen only)

766

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum labii (oris)

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5939 2865 3040
Only index persons 5167 2575 2592
Unadjusted period prevalence (%)
Whole population 0.08 0.08 0.08
Only index persons 0.10 0.09 0.10
Median age at first event (years)
Whole population 56.86 56.25 57.39
Only index persons 55.08 55.45 54.71

-FinnGen-

Key figures

All Female Male
Number of individuals 766 390 376
Unadjusted period prevalence (%) 0.15 0.14 0.17
Median age at first event (years) 59.34 55.85 62.96

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
800
Matched controls
8000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EAA10
NOMESCO Finland
Excision of lesion of lip
99.8
307.7
234
33
D10.09
ICD-10 Finland
Benign tumor of the lip UNS
+∞
295.7
265
*
D10.04
ICD-10 Finland
Lower lip tumor in the lower lip mucosa
+∞
222.6
203
*
TEA00
NOMESCO Finland
Biopsy of lip
50.0
159.1
93
21
D10.00
ICD-10 Finland
Upper lip tumor in upper lip on lip lip border
+∞
130.9
122
*
D10.01
ICD-10 Finland
Uper lip tumor in the upper lip mucosa
+∞
74.1
70
*
D10.03
ICD-10 Finland
Lower lip tumor in the lower lip at the lip red border
+∞
59.1
56
*
21000
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Lip
+∞
43.1
41
*
D10.0
ICD-10 Finland
Benign neoplasm: Lip
+∞
43.1
41
*
8070/3-C00.1
ICD-O-3
Squamous cell carcinoma, NOS, of external lower lip
188.2
35.0
36
*
2100A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Lip
+∞
30.4
29
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.5
27.7
46
74
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
268.9
25.8
26
*
C00.1
ICD-10 Finland
Malignant neoplasm: External lower lip
72.3
24.9
28
*
D18.0
ICD-10 Finland
Haemangioma, any site
6.5
24.2
40
64
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.9
22.1
113
425
EAA30
NOMESCO Finland
Partial excision of lower lip
64.4
22.0
25
*
4381
FHL
Exemption of local change
204.9
19.6
20
*
D10.05
ICD-10 Finland
Lower lip tumor in lower lip mucosa and on lip lip border
+∞
17.8
17
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.4
13.7
35
83
EKA10
NOMESCO Finland
iopsy of buccal mucosa
4.5
13.2
32
73
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
5.1
12.0
25
50
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.7
11.9
38
107
D20
ICPC
Mouth/tongue/lip symptom/complaint
3.0
11.8
52
179
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.9
11.0
32
84
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
10.8
154
888
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.4
10.5
37
111
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
10.1
59
237
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.4
9.5
34
103
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
3.6
9.4
31
89
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.8
9.2
158
962
K13.78
ICD-10 Finland
Other change in the oral mucosa
3.8
8.7
26
70
SPAT1153
SPAT
Removal of sutures
1.6
8.3
251
1775
K13.03
ICD-10 Finland
Keilit UNS
14.7
8.2
13
9
C00.9
ICD-10 Finland
Malignant neoplasm: Lip, unspecified
33.7
8.1
10
*
K13.09
ICD-10 Finland
Disease of the lips UNS
33.7
8.1
10
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
7.8
210
1439
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
25.3
7.6
10
*
L57.0
ICD-10 Finland
Actinic keratosis
1.9
7.4
97
541
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
7.3
470
3884
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
7.3
89
486
SXA10
NOMESCO Finland
Oral mucosal sampling
5.7
7.1
19
34
D83
ICPC
Mouth/tongue/lip disease
10.1
7.0
13
13
J01DB01
ATC
cefalexin; oral
1.6
6.8
628
5563
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.9
6.8
81
438
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
2.6
6.8
38
150
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
6.8
98
565
K13.29
ICD-10 Finland
Indefinite leukoplakia
5.6
6.6
18
33
D23.0
ICD-10 Finland
Benign neoplasm: Skin of lip
8.8
6.6
13
15
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
6.6
511
4346
EKB00
NOMESCO Finland
Excision of tumour or other lesion of cheek
10.1
6.5
12
12
H02AB07
ATC
prednisone; oral
1.7
6.5
112
681
R01AD09
ATC
mometasone; nasal
1.5
6.4
321
2503
TQW99
NOMESCO Finland
Other minor procedure on skin
2.3
6.4
49
224
S18
ICPC
Laceration/cut
1.5
6.4
348
2758
K11.69
ICD-10 Finland
Mukocele UNS
6.6
6.4
15
23
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
6.3
102
607
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
6.3
257
1919
D10.07
ICD-10 Finland
Lip tumor in both lips of the mucous membrane
+∞
6.3
6
*
EJB00
NOMESCO Finland
Excision of ranula
+∞
6.3
6
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
6.2
356
2842
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
3.8
6.1
18
48
Z01.2
ICD-10 Finland
Dental examination
1.5
6.1
313
2445

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
399
2561
2.11
23.51
2.5
2.1
—
—
—
0
0
120
675
1.92
9.00
3.9
4.3
—
—
—
0
0
531
4510
1.53
7.21
4.7
4.4
—
—
—
0
0
577
5030
1.53
6.58
7.8
7.6
79.11
79.43
u/l
0.05
536
4715
373
2999
1.46
6.31
5.1
5.8
1.21
1.21
mmol/l
0.11
312
2703
373
3010
1.45
6.13
6.2
6.1
—
—
—
0
0
403
3309
1.44
5.98
5.7
5.8
0.19
0.19
e9/l
0.09
344
2909
399
3276
1.43
5.89
5.8
6.6
1.21
1.21
mmol/l
0.01
330
2773
55
283
2.01
5.35
1.2
1.3
—
—
—
0
0
394
3271
1.40
5.24
5.7
5.6
1.84
1.87
e9/l
0.24
346
2891
385
3187
1.40
5.20
5.6
5.6
0.58
0.59
e9/l
0.38
332
2761
260
2011
1.43
5.16
4.3
4.0
—
—
—
0
0
339
2754
1.40
5.07
2.2
2.0
94.78
94.65
pmol/l
0.02
165
1415
385
3198
1.39
5.04
5.6
5.6
0.04
0.04
e9/l
1.85
333
2775
365
3013
1.39
4.92
5.7
5.7
2.81
2.87
%
0.19
331
2823
73
425
1.79
4.90
2.9
2.8
3.80
6.13
e9/l
1.44
40
341
355
2919
1.39
4.89
5.8
5.7
0.62
0.66
%
0.93
320
2732
371
3087
1.38
4.69
5.9
5.8
27.47
27.22
%
0.16
337
2903
452
3884
1.38
4.67
4.5
4.6
6.84
6.73
mmol/l
0.49
423
3654
544
4822
1.40
4.64
4.8
4.2
12.74
12.74
mm/h
0.00
478
4421
364
3024
1.37
4.63
6.2
6.0
8.61
8.74
%
0.35
331
2841
365
3048
1.36
4.43
5.6
5.6
57.58
57.61
%
0.02
332
2870
18
60
3.05
4.42
1.6
1.5
13.91
29.21
u/l
1.27
11
48
434
3733
1.36
4.31
8.7
9.0
3.92
4.15
e9/l
1.67
378
3287
14
42
3.37
4.06
2.6
1.4
—
—
—
0
0
87
563
1.61
3.99
1.4
1.4
—
—
—
0
0
278
2257
1.36
3.93
3.0
3.4
2.36
2.35
mmol/l
0.31
224
1973
206
1604
1.38
3.76
2.5
2.3
—
—
—
0
0
374
3194
1.32
3.69
15.9
15.5
1.27
1.28
inr
0.06
81
926
19
73
2.64
3.66
1.9
1.5
41.08
65.67
%
1.62
13
51
682
6378
1.47
3.66
16.8
15.0
22.87
24.65
mg/l
0.77
559
5115
634
5861
1.39
3.55
5.4
4.7
1.89
2.14
mu/l
0.64
551
5303
116
833
1.46
3.32
1.3
1.3
—
—
—
0
0
255
2091
1.32
3.26
2.6
2.4
—
—
—
0
0
667
6245
1.41
3.24
5.0
4.7
5.99
5.98
mmol/l
0.06
576
5649
13
40
3.29
3.15
3.3
2.0
—
—
—
0
0
70
462
1.56
3.00
1.1
1.2
—
—
—
0
0
53
329
1.65
2.91
3.5
3.7
—
—
—
0
0
82
565
1.50
2.90
3.0
3.1
122.59
207.65
ng/l
3.50
71
517
121
904
1.40
2.80
1.1
1.2
—
—
—
0
0
307
2627
1.27
2.76
2.4
2.2
77.29
77.74
nmol/l
0.10
251
2321
64
424
1.55
2.71
2.8
3.0
—
—
—
0
0
351
3059
1.26
2.69
2.7
2.6
—
—
—
0
0
645
6059
1.33
2.64
4.3
4.0
1.27
1.29
mmol/l
0.25
553
5491
207
1694
1.30
2.62
2.4
2.1
2.91
3.10
mg/l
0.58
159
1427
681
6457
1.37
2.56
5.4
5.0
2.70
2.71
mmol/l
0.14
592
5889
699
6656
1.40
2.55
19.5
17.5
3.96
3.98
mmol/l
1.40
670
6474
163
1295
1.32
2.55
1.9
1.8
1076.17
1179.47
nmol/l
0.61
102
971
525
4813
1.26
2.54
4.4
3.9
14.88
14.84
pmol/l
0.14
439
4330
697
6637
1.39
2.52
19.4
17.4
139.65
139.69
mmol/l
0.15
672
6462
464
4199
1.25
2.49
3.2
3.1
46.96
50.27
u/l
0.42
418
3901
170
1364
1.31
2.48
1.2
1.2
2.29
1.40
u/ml
0.33
33
360
668
6326
1.34
2.44
4.9
4.5
4.57
4.61
mmol/l
0.33
587
5810
246
2079
1.26
2.39
2.5
2.4
59.91
60.93
u/l
0.10
220
1924
390
3472
1.24
2.39
6.1
6.2
11.86
11.30
umol/l
0.27
362
3301
101
753
1.39
2.38
2.7
2.8
7.79
8.90
umol/l
0.21
89
672
44
276
1.63
2.37
3.5
4.1
24.98
25.11
mmol/l
0.07
36
260
67
464
1.48
2.34
1.4
1.5
—
—
—
0
0
201
1670
1.27
2.23
1.6
1.6
21.45
20.60
nmol/l
0.28
154
1401
710
6807
1.38
2.22
11.9
10.6
27.67
26.03
u/l
0.66
677
6549
29
165
1.79
2.22
2.4
2.6
—
—
—
0
0
327
2873
1.23
2.22
4.6
4.7
35.59
35.27
g/l
0.50
295
2674
51
338
1.54
2.20
2.9
3.9
—
—
—
0
0
662
6286
1.31
2.18
5.0
4.5
1.45
1.46
mmol/l
0.22
578
5733
239
2036
1.25
2.14
2.2
2.1
178.38
262.71
u/l
1.14
216
1917
733
7074
1.43
2.12
25.0
22.0
40.01
40.02
%
0.02
676
6591
733
7075
1.43
2.11
25.0
21.9
6.89
6.75
e9/l
0.29
708
6866
733
7075
1.43
2.11
24.9
21.8
91.09
91.23
fl
0.38
717
6955
733
7077
1.43
2.08
25.0
21.9
4.47
4.47
e12/l
0.01
708
6870
81
597
1.40
2.06
2.7
2.5
5.76
6.82
ug/l
0.29
64
527
733
7079
1.42
2.06
25.2
22.0
134.62
134.93
g/l
0.21
717
6955
629
5954
1.26
1.99
6.4
6.0
40.27
40.06
mmol/mol
0.21
550
5474
732
7076
1.41
1.96
24.9
21.8
30.31
30.35
pg
0.20
717
6954
238
2049
1.23
1.91
3.5
3.2
—
—
—
0
0
37
236
1.60
1.90
1.0
1.1
—
—
—
0
0
8
28
2.88
1.86
1.0
1.0
—
0.18
—
0
6
6
17
3.55
1.84
2.5
1.1
0.60
2.61
mmol/l
—
6
17
81
612
1.36
1.80
1.4
1.4
—
—
—
0
0
11
47
2.36
1.78
3.5
2.6
—
—
—
0
0
40
265
1.54
1.77
2.1
1.9
—
—
—
0
0
730
7072
1.37
1.74
25.0
21.9
248.41
246.49
e9/l
0.34
710
6883
185
2165
0.81
1.74
3.2
3.0
—
—
—
0
0
81
616
1.35
1.73
3.4
3.7
2.37
1.93
mmol/l
0.53
67
512
690
6635
1.29
1.72
16.2
14.1
—
—
—
0
0
21
118
1.80
1.71
2.4
1.8
191.10
224.54
pmol/l
0.67
21
111
62
453
1.40
1.69
3.8
3.5
4.87
5.16
kpa
1.62
56
437
13
62
2.11
1.66
1.5
1.3
4224.25
309760.68
e6/l
—
8
40
14
69
2.05
1.65
1.6
2.8
—
—
—
0
0
290
2581
1.19
1.62
4.1
3.8
42.02
52.75
ng/l
0.26
214
1871
146
1213
1.25
1.61
1.5
1.5
2.37
2.54
g/l
0.28
81
737
5
14
3.59
1.61
4.2
2.2
0.81
0.99
ug/l
—
5
14
265
2342
1.20
1.59
5.5
5.0
4.08
2.81
ug/l
0.36
224
2080
75
572
1.34
1.59
4.4
2.5
74.45
69.54
e9/l
0.61
58
442
37
248
1.52
1.58
2.5
2.3
11.44
10.55
g/l
0.33
25
217
287
2561
1.19
1.54
2.9
3.5
5.79
5.85
ph
0.10
14
172
0
42
0.00
1.53
0.0
1.2
—
—
—
0
0
0
44
0.00
1.51
0.0
1.7
—
9.47
—
0
44
21
124
1.71
1.48
1.8
1.5
—
—
—
0
0
165
1404
1.22
1.47
1.9
1.7
431.08
4374883.69
pmol/l
0.50
119
1143
91
723
1.29
1.46
2.6
4.3
4.32
28.33
ug/l
1.40
68
608
217
1897
1.20
1.46
3.7
4.1
—
—
—
0
0
55
406
1.38
1.44
1.3
1.2
—
—
—
0
0
190
1643
1.21
1.43
4.0
3.9
91.87
89.16
%
0.75
181
1608
47
338
1.41
1.43
2.5
2.4
—
—
—
0
0
15
81
1.87
1.41
1.0
1.2
—
—
—
0
0
233
2061
1.18
1.37
3.1
3.1
1404.39
1438.86
ng/l
0.06
192
1763
119
987
1.24
1.35
2.4
2.3
2.34
2.32
g/l
0.14
105
912
72
561
1.31
1.34
3.6
3.0
66.47
66.75
g/l
0.10
56
505
9
42
2.16
1.34
1.2
1.0
—
—
—
0
0
221
1951
1.18
1.32
3.3
3.9
7.40
7.40
ph
0.19
29
372
12
62
1.95
1.28
2.3
1.3
—
—
—
0
0
98
801
1.25
1.27
1.7
1.4
—
—
—
0
0
68
531
1.31
1.26
6.2
8.0
—
—
—
0
0
62
478
1.32
1.26
2.5
2.5
—
—
—
0
0
346
3176
1.16
1.26
3.3
3.8
0.00
0.00
estimate
0.50
50
634
257
2847
0.86
1.26
9.2
9.4
0.00
0.00
e9/l
0.34
209
2332
43
313
1.40
1.25
1.4
1.9
1.39
1.50
g/l
0.43
35
273
76
604
1.29
1.24
3.5
2.3
35.97
32.58
u/l
0.35
58
506
73
579
1.29
1.21
2.9
1.9
361.44
375.72
nmol/l
0.24
66
533
24
156
1.56
1.21
1.7
1.5
339.67
298.06
mu/l
0.25
24
143
302
2752
1.16
1.20
3.1
2.7
145.44
129.06
ug/l
0.28
263
2512
229
2047
1.17
1.17
3.0
3.1
7.38
7.57
mmol/l
0.26
174
1693
15
87
1.74
1.15
1.0
1.2
0.68
0.59
nmol/l
0.42
15
79
111
931
1.22
1.15
2.4
2.4
22.38
22.42
%
0.01
89
798
5
20
2.51
1.15
5.4
2.2
—
—
—
0
0
149
1287
1.19
1.15
2.8
3.1
2.46
2.45
mmol/l
0.25
132
1131
133
1137
1.20
1.14
2.9
2.8
1.32
1.16
e6/l
0.18
70
665
25
167
1.51
1.13
1.8
1.6
7178.39
16809.37
e6/l
1.12
18
120
344
3178
1.14
1.11
4.7
5.2
0.00
0.00
estimate
-0.00
45
595
104
871
1.22
1.10
4.7
5.4
0.97
1.02
mmol/l
1.02
87
798
348
3219
1.14
1.10
3.3
3.8
0.00
0.01
estimate
0.50
42
576
114
964
1.21
1.10
2.2
2.0
—
—
—
0
0
10
52
1.93
1.06
1.8
1.3
39.60
28.53
%
—
5
34
31
220
1.43
1.06
1.8
2.3
36.98
38.08
g/l
0.36
18
190
7
33
2.13
1.05
7.1
6.0
—
—
—
0
0
183
1622
1.17
1.04
5.5
6.6
—
—
—
0
0
75
611
1.25
1.03
2.1
2.3
0.22
0.21
g/l
0.34
70
569
69
557
1.26
1.02
2.7
3.5
—
—
—
0
0
93
777
1.22
1.02
2.1
1.7
—
—
—
0
0
87
722
1.23
1.02
2.6
2.2
103.43
127.51
ug/g
0.60
61
560
5
23
2.18
0.98
2.6
3.1
—
—
—
0
0
59
472
1.27
0.95
3.2
2.1
11.69
13.07
nmol/l
0.55
49
418
88
738
1.22
0.94
1.5
1.3
—
—
—
0
0
158
1400
1.16
0.91
1.7
1.7
1.08
1.21
mg/l
0.25
118
1075
6
29
2.08
0.89
1.0
1.1
—
0.22
—
0
11
6
29
2.08
0.89
11.2
16.6
—
—
—
0
0
124
1080
1.18
0.89
3.0
3.0
3.39
2.17
e6/l
0.78
62
609
6
31
1.94
0.84
1.2
1.4
—
—
—
0
0
165
1476
1.15
0.84
3.2
3.8
—
—
—
0
0
215
1959
1.13
0.83
3.2
3.2
286.78
224.98
mg/l
0.10
137
1261
42
329
1.29
0.82
1.4
1.3
—
—
—
0
0
191
1731
1.14
0.80
2.7
2.7
6193.22
7119.93
umol/l
0.10
157
1497
43
339
1.28
0.80
2.5
3.4
25.73
25.17
mmol/l
0.54
43
331
17
114
1.50
0.80
3.3
2.0
68.45
59.92
%
1.16
17
114
0
25
0.00
0.79
0.0
2.3
—
4713.36
—
0
14
0
25
0.00
0.79
0.0
1.1
—
37.40
—
0
5
8
48
1.67
0.79
1.1
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
2.4
—
365.27
—
0
22
75
636
1.20
0.75
1.5
1.5
—
—
—
0
0
5
24
2.09
0.74
2.6
3.4
28.60
33.42
umol/l
—
5
19
253
2344
1.12
0.74
3.9
3.8
63.82
133.42
e6/l
1.06
170
1693
26
193
1.36
0.74
1.6
1.5
254.87
284.73
ug/g
0.33
15
114
44
354
1.26
0.72
6.4
9.0
—
—
—
0
0
97
845
1.17
0.72
1.4
1.3
946.67
473.30
titre
0.74
21
191
529
5474
0.90
0.71
19.8
17.7
14.60
15.11
%
1.59
523
5382
121
1074
1.15
0.70
2.4
2.4
12.93
12.86
umol/l
0.04
106
998
202
1855
1.12
0.69
3.5
3.2
0.47
0.48
e6/l
0.02
150
1431
90
782
1.17
0.69
3.0
2.5
2.08
1.79
%
1.59
72
702
5
27
1.86
0.68
2.0
3.6
—
—
—
0
0
224
2071
1.11
0.68
3.7
3.8
18.48
9.32
mg/mmol
0.47
133
1299
120
1068
1.15
0.67
3.7
3.2
0.82
0.82
mmol/l
0.27
107
994
7
121
0.57
0.67
1.3
1.4
—
—
—
0
0
7
43
1.63
0.67
1.3
1.4
209.59
153.15
pmol/l
—
7
43
142
1280
1.13
0.66
5.4
3.9
61.57
292.56
ng/l
4.30
112
1024
20
146
1.38
0.64
1.6
1.3
—
—
—
0
0
194
1786
1.11
0.64
3.5
3.2
—
—
—
0
0
49
406
1.22
0.63
1.3
1.4
—
—
—
0
0
156
1707
0.89
0.61
3.7
4.1
0.00
0.01
estimate
0.69
41
579
5
30
1.67
0.61
3.0
2.4
40.00
44.86
umol/l
—
5
24
155
1413
1.12
0.61
2.8
2.6
3.76
5.44
e6/l
1.43
138
1278
0
20
0.00
0.60
0.0
1.2
—
17.08
—
0
13
102
907
1.14
0.59
1.7
1.8
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
4.51
—
0
17
19
140
1.37
0.58
5.1
4.1
1.51
2.87
mmol/l
—
10
96
0
23
0.00
0.58
0.0
2.1
—
—
—
0
0
35
283
1.25
0.57
3.1
3.5
459.61
1417.40
u/ml
0.73
28
241
14
98
1.44
0.56
1.3
1.3
—
—
—
0
0
24
185
1.31
0.56
2.9
5.0
—
—
—
0
0
149
1364
1.11
0.55
2.9
3.0
541.19
548.22
mosm/kgh2o
0.15
122
1178
9
62
1.46
0.53
1.2
1.2
—
—
—
0
0
27
215
1.26
0.51
1.7
2.0
21.14
21.27
s
0.06
21
193
13
92
1.42
0.50
1.1
1.1
—
8.82
—
0
6
13
92
1.42
0.50
1.8
2.8
—
—
—
0
0
222
2084
1.09
0.50
3.5
3.2
29.68
32.72
u/l
1.27
208
1984
7
46
1.53
0.48
2.9
1.6
13.03
10.46
%
—
7
46
15
111
1.36
0.47
1.5
1.6
—
—
—
0
0
11
77
1.43
0.45
1.1
1.1
0.65
1.63
u/ml
—
6
37
5
84
0.59
0.45
1.4
1.2
—
—
—
0
0
58
509
1.15
0.43
3.2
4.0
76.91
87.88
ng/l
0.72
45
455
215
2029
1.08
0.43
3.5
3.3
61.71
106.51
e6/l
0.56
163
1585
48
552
0.86
0.43
3.7
3.8
—
—
—
0
0
5
32
1.57
0.42
1.0
1.0
—
—
—
0
0
8
57
1.41
0.42
1.4
1.9
—
—
—
0
0
41
476
0.85
0.41
3.4
4.3
0.00
0.74
%
0.59
12
134
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
2.4
—
—
—
0
0
16
205
0.78
0.40
10.9
9.6
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
35
297
1.19
0.40
3.5
3.4
14.46
66.13
u/ml
2.41
35
283
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
18
142
1.27
0.38
2.9
2.5
—
—
—
0
0
11
80
1.38
0.38
1.5
1.1
—
—
—
0
0
163
1735
0.92
0.38
1.7
1.6
1.32
1.39
mmol/l
0.47
130
1448
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
446
4583
0.94
0.37
4.2
3.9
—
—
—
0
0
18
223
0.80
0.36
1.1
1.1
—
—
—
0
0
14
108
1.30
0.35
1.3
1.5
—
—
—
0
0
34
293
1.17
0.34
3.1
2.8
—
—
—
0
0
12
155
0.77
0.33
3.6
3.9
31.17
28.19
mg/l
—
6
98
127
1355
0.93
0.32
3.3
3.0
0.79
0.78
ug/l
0.08
72
900
150
1414
1.07
0.32
3.4
4.1
1.02
1.02
kg/l
0.25
30
199
71
648
1.10
0.31
1.7
1.6
—
—
—
0
0
86
793
1.09
0.31
5.3
6.8
1.39
1.35
mmol/l
0.03
66
624
13
102
1.28
0.30
4.1
2.8
—
—
—
0
0
7
55
1.28
0.30
1.1
1.1
—
—
—
0
0
49
545
0.89
0.30
3.5
3.4
1.21
1.23
mmol/l
1.00
42
469
43
481
0.89
0.29
1.5
1.4
—
—
—
0
0
7
57
1.23
0.29
1.1
1.1
—
—
—
0
0
8
62
1.29
0.28
1.0
1.1
—
—
—
0
0
9
116
0.77
0.27
1.6
2.8
—
—
—
0
0
17
141
1.21
0.26
1.1
1.2
—
—
—
0
0
10
77
1.30
0.26
1.0
1.2
—
—
nmol/l
—
0
0
5
75
0.66
0.26
1.2
9.3
6.30
6.87
mmol/l
—
5
61
44
397
1.11
0.25
1.7
1.6
—
—
—
0
0
18
151
1.20
0.25
1.8
1.7
—
—
—
0
0
14
114
1.23
0.25
1.1
1.6
—
—
—
0
0
9
75
1.20
0.25
2.7
3.5
—
—
—
0
0
14
168
0.83
0.23
1.5
1.9
—
—
—
0
0
28
247
1.14
0.23
2.1
3.2
0.65
0.24
g/l
—
10
96
107
1012
1.07
0.23
1.3
1.3
6.14
12.34
u/ml
0.62
36
379
10
79
1.27
0.22
1.6
1.2
—
—
—
0
0
85
798
1.07
0.22
5.4
6.7
5.13
5.12
kpa
0.05
78
759
85
799
1.07
0.21
5.4
6.7
12.41
12.05
kpa
0.31
78
763
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
11.3
—
6.08
—
0
10
8
102
0.78
0.21
2.6
2.8
—
—
—
0
0
0
12
0.00
0.21
0.0
6.5
—
—
—
0
0
5
43
1.16
0.21
1.2
1.7
104.80
80.79
umol/l
—
5
43
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
6.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
18.19
—
0
14
0
14
0.00
0.20
0.0
1.5
—
34.74
—
0
8
0
14
0.00
0.20
0.0
1.6
—
1.19
—
0
14
6
49
1.23
0.20
1.2
1.1
—
2.37
—
0
9
46
499
0.92
0.19
1.4
1.4
—
—
—
0
0
6
51
1.18
0.19
1.2
1.2
—
—
—
0
0
14
118
1.19
0.19
1.1
1.2
—
—
—
0
0
15
128
1.18
0.18
2.7
2.4
—
—
—
0
0
7
63
1.11
0.17
1.6
2.8
—
—
—
0
0
5
68
0.73
0.17
1.4
1.6
—
—
—
0
0
80
759
1.06
0.17
1.6
1.6
—
—
—
0
0
24
266
0.90
0.16
1.8
1.7
—
—
—
0
0
8
73
1.10
0.15
1.6
2.2
—
—
—
0
0
6
79
0.76
0.15
1.3
1.6
—
—
—
0
0
44
472
0.93
0.15
4.1
4.4
—
—
—
0
0
10
119
0.84
0.15
4.4
3.7
54.00
57.79
%
—
10
119
9
78
1.16
0.15
1.7
2.5
—
—
—
0
0
9
81
1.11
0.15
1.3
1.3
11.12
49.17
mu/l
—
9
73
22
198
1.11
0.14
3.0
3.0
—
—
—
0
0
111
1070
1.04
0.13
1.3
1.3
17.83
37.47
iu/ml
4.13
35
342
15
169
0.89
0.12
1.5
1.6
—
—
—
0
0
15
169
0.89
0.12
1.5
1.9
—
—
—
0
0
15
168
0.89
0.11
1.5
1.9
—
—
—
0
0
40
376
1.07
0.11
1.5
1.3
137.53
287.58
u/ml
1.01
35
339
10
86
1.16
0.11
1.0
1.1
—
—
—
0
0
18
163
1.11
0.11
1.1
1.2
—
—
—
0
0
15
167
0.90
0.10
1.2
1.3
—
—
—
0
0
17
187
0.91
0.10
1.3
1.2
—
—
—
0
0
26
279
0.93
0.10
1.2
1.1
—
28.50
—
0
6
10
114
0.88
0.09
1.1
1.2
—
—
—
0
0
10
114
0.88
0.09
4.1
3.3
2.94
4.31
e9/l
—
10
114
19
174
1.09
0.09
5.1
3.8
7.42
7.42
ph
0.21
19
150
17
155
1.10
0.09
1.5
1.3
205.86
242.80
miu/ml
—
7
76
6
54
1.11
0.09
1.0
1.0
—
—
—
0
0
6
56
1.07
0.08
1.3
1.3
—
—
—
0
0
10
113
0.88
0.08
1.3
1.1
—
—
—
0
0
5
60
0.83
0.08
1.2
1.1
—
—
—
0
0
5
62
0.81
0.08
1.2
1.2
—
—
—
0
0
10
88
1.14
0.08
1.0
1.4
33.25
31.95
g/l
—
10
79
17
156
1.09
0.08
3.8
3.4
0.78
0.88
nmol/l
0.31
12
124
7
68
1.03
0.08
1.7
2.4
—
—
—
0
0
25
266
0.94
0.07
1.0
1.1
—
—
—
0
0
8
76
1.05
0.07
1.0
1.2
—
—
—
0
0
9
87
1.03
0.07
1.0
1.1
—
—
—
0
0
172
1745
0.98
0.06
3.1
3.5
—
—
—
0
0
25
263
0.95
0.05
4.7
4.5
—
—
—
0
0
13
141
0.92
0.05
3.0
2.0
127.13
129.73
g/l
—
8
102
11
100
1.10
0.05
1.3
1.1
—
—
—
0
0
10
110
0.91
0.05
1.1
1.2
210.00
288.17
u/ml
—
5
63
17
181
0.94
0.05
2.1
2.3
51.89
89.10
ug/min
—
9
109
165
1670
0.98
0.04
1.3
1.4
—
—
—
0
0
11
101
1.09
0.04
6.4
1.7
—
—
—
0
0
11
102
1.08
0.03
1.3
1.0
—
—
—
0
0
24
231
1.04
0.03
1.5
1.6
—
—
—
0
0
30
291
1.03
0.02
2.0
1.9
0.85
2.58
ug/l
0.97
22
257
50
510
0.98
0.02
3.4
4.3
0.11
0.13
%
0.07
19
165
53
539
0.98
0.02
3.3
4.2
1.14
0.97
%
0.24
22
196
15
157
0.95
0.01
1.0
1.1
—
—
—
0
0
49
482
1.02
0.01
3.0
4.2
0.47
0.54
%
0.16
19
160
15
156
0.96
0.00
1.5
1.9
—
—
—
0
0
36
354
1.02
0.00
4.8
3.4
4.51
4.55
pmol/l
0.12
28
306
16
157
1.02
0.00
3.4
4.2
—
—
—
0
0
11
112
0.98
0.00
1.1
1.4
—
—
—
0
0
13
132
0.98
0.00
1.5
2.0
—
—
—
0
0
41
413
0.99
0.00
1.2
1.2
161.66
127.44
iu/ml
—
9
169
32
321
1.00
0.00
1.6
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.04
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
330.60
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
18.11
—
0
7
8
83
0.96
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
7.6
2.4
14.22
13.18
%
—
5
54
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
1.9
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.4
—
—
—
0
0
14
140
1.00
-0.00
6.9
3.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_LIP and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_LIP 1.028 [0.9, 1.17] 0.68
Birth year 0.996 [0.99, 1.0] 0.394

During the follow-up period (1.1.1998 — 31.12.2019), 393 out of 2264 females with CD2_BENIGN_LIP died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_LIP 1.101 [0.97, 1.24] 0.126
Birth year 0.988 [0.98, 1.0] 0.021

During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 2302 males with CD2_BENIGN_LIP died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_LIP.

N-year risk Females Males
1 0.092% 0.172%
5 0.595% 1.164%
10 1.653% 3.209%
15 3.195% 6.197%
20 5.499% 10.545%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_LIP – Benign neoplasm: Lip

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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