Viral encephalitis, not elsewhere classified/unspecified

AB1_VIRAL_ENCEPHALITIS_NOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A85, A86
  • Hospital discharge: ICD-9 06[4]
  • Hospital discharge: ICD-8 06[4]
  • Cause of death: ICD-10 A85, A86
  • Cause of death: ICD-9 06[4]
  • Cause of death: ICD-8 06[4]

2 out of 7 registries used, show all original rules.

767

4. Check minimum number of events

None

767

5. Include endpoints

None

767

6. Filter based on genotype QC (FinnGen only)

740

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_CNS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6491 3070 3393
Only index persons 5729 2699 3030
Unadjusted period prevalence (%)
Whole population 0.09 0.09 0.09
Only index persons 0.11 0.10 0.12
Median age at first event (years)
Whole population 52.94 56.53 49.53
Only index persons 52.07 55.63 48.89

-FinnGen-

Key figures

All Female Male
Number of individuals 740 381 359
Unadjusted period prevalence (%) 0.15 0.14 0.16
Median age at first event (years) 57.15 54.30 60.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
767
Matched controls
7670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A86
ICD-10 Finland
Unspecified viral encephalitis
+∞
307.7
710
*
TAB00
NOMESCO Finland
Lumbar puncture
19.9
263.0
227
159
N03AX14
ATC
levetiracetam; systemic
14.9
110.5
103
79
AA1AD
NOMESCO Finland
CT of head and brain
5.0
108.2
390
1311
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.3
106.8
182
312
R41.0
ICD-10 Finland
Disorientation, unspecified
12.1
99.9
106
100
XA800
NOMESCO Finland
Neuropsychological investigation
10.2
98.9
120
137
R56.8
ICD-10 Finland
Other and unspecified convulsions
9.0
97.2
132
174
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.3
90.0
130
184
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
11.4
81.5
89
87
A87.9
ICD-10 Finland
Viral meningitis, unspecified
+∞
74.2
70
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
9.3
73.4
94
114
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
12.7
71.5
72
62
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
180.2
64.1
66
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
12.0
58.6
61
55
F05.9
ICD-10 Finland
Delirium, unspecified
11.8
57.0
60
55
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.7
55.1
147
369
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
51.4
224
796
N03AF02
ATC
oxcarbazepine; oral
7.8
50.4
73
102
Z2445
NOMESCO Finland
Psychologist
6.3
45.6
82
144
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
10.1
45.6
53
56
A85.8
ICD-10 Finland
Other specified viral encephalitis
+∞
44.2
42
*
5AB01, ,
NOMESCO Finland
159.1
43.3
45
*
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
+∞
42.1
40
*
R50.9
ICD-10 Finland
Fever, unspecified
3.3
38.7
182
667
XF400
NOMESCO Finland
ECG with 12 standard connections
3.2
38.1
188
708
N03AG01
ATC
valproic acid; systemic, rectal
4.3
33.0
91
231
R4120
NOMESCO Finland
Occupational therapy
4.1
30.8
91
243
R51.80
ICD-10 Finland
Headache
2.9
30.6
174
703
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.5
30.4
118
380
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
29.8
180
750
183
Kela drug reimbursment
Lamotrigin and topiramate
11.5
28.6
30
27
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
28.5
130
462
XA400
NOMESCO Finland
EEG
28.1
26.0
35
13
G03.9
ICD-10 Finland
Meningitis, unspecified
75.1
26.0
29
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
25.0
248
1296
N03AX18
ATC
lacosamide; systemic
24.4
25.0
35
15
A41.9
ICD-10 Finland
Sepsis, unspecified
5.1
24.7
54
113
ZX120
NOMESCO Finland
Intravenous
3.2
24.5
110
386
WX892
NOMESCO Finland
Monitored bed care
3.4
23.8
93
299
G41.9
ICD-10 Finland
Status epilepticus, unspecified
29.3
23.3
31
11
B94.1
ICD-10 Finland
Sequelae of viral encephalitis
+∞
23.0
22
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
6.9
22.3
35
53
N03AB02
ATC
phenytoin; systemic
7.2
21.3
32
46
N71
ICPC
Meningitis/encephalitis
215.6
20.7
21
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
19.5
20.1
30
16
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
8.6
19.4
25
30
A84.8
ICD-10 Finland
Other tick-borne viral encephalitis
+∞
18.8
18
*
TKC20
NOMESCO Finland
Catheterisation of bladder
3.2
18.8
79
265
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
18.7
375
2502
G05.1*A85.0
ICD-10 Finland
Encephalitis, myelitis or encephalomyelitis (in) enteroviral
+∞
17.8
17
*
B00.4
ICD-10 Finland
Herpesviral encephalitis
+∞
17.8
17
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
17.4
195
1051
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
16.8
124
559
WX730
NOMESCO Finland
Conventional respirator
12.0
16.1
29
25
A84.9
ICD-10 Finland
Tick-borne viral encephalitis, unspecified
+∞
15.7
15
*
N05BA09
ATC
clobazam; oral
16.5
15.3
24
15
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
14.9
97
411
R11
ICD-10 Finland
Nausea and vomiting
2.7
14.9
87
350
Z3231
NOMESCO Finland
Registered nurse
1.9
14.8
228
1369
R4150
NOMESCO Finland
Neuropsychological rehabilitation
12.2
14.7
26
22
N03AF01
ATC
carbamazepine; oral, rectal
3.3
14.6
57
183
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
14.5
80
312
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
14.5
136
678
R42
ICD-10 Finland
Dizziness and giddiness
2.0
14.4
185
1041
J05AB11
ATC
valaciclovir; oral
2.2
14.3
130
640
G04.8
ICD-10 Finland
Other encephalitis, myelitis and encephalomyelitis
+∞
13.6
13
*
G05.1
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
+∞
13.6
13
*
N03AX09
ATC
lamotrigine; oral
3.3
13.3
52
167
N29
ICPC
Neurological sympt/complt other
5.2
13.2
27
53
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.6
13.1
25
46
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.0
12.9
28
58
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
12.7
155
852
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.6
12.7
43
126
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
+∞
12.5
12
*
N05BA01
ATC
diazepam; systemic, rectal
2.2
12.5
115
567
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.6
12.4
77
319
G41.0
ICD-10 Finland
Grand mal status epilepticus
38.2
12.2
15
*
N28
ICPC
Limited function/disability (N)
5.6
12.2
23
42
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
12.1
70
280
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.3
12.1
98
459
R47.0
ICD-10 Finland
Dysphasia and aphasia
10.3
12.1
23
23
H02AB06
ATC
prednisolone; systemic
1.7
12.0
359
2595
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.5
12.0
29
66
N05AH04
ATC
quetiapine; oral
2.0
12.0
151
839
E86
ICD-10 Finland
Volume depletion
4.3
11.9
31
75
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
11.8
106
517
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
9.8
11.8
23
24
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
11.7
133
711
F05.8
ICD-10 Finland
Other delirium
12.8
11.7
20
16
Z2221
NOMESCO Finland
Medical doctor
1.8
11.7
214
1343
N03AX16
ATC
[U] pregabalin
1.9
11.6
181
1079
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
23.3
11.6
16
7
G02.0*B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
11.5
11
*
Z3226
NOMESCO Finland
Physiotherapist
2.0
11.4
149
836
R53
ICD-10 Finland
Malaise and fatigue
1.8
11.3
198
1225
R4110
NOMESCO Finland
Physiotherapy
1.8
11.1
214
1359
N03AE01
ATC
clonazepam; systemic
2.9
11.1
53
191
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.2
11.0
43
138
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.7
10.7
58
224
ZXD05
NOMESCO Finland
Urgent procedure
1.7
10.6
238
1578
F07.1
ICD-10 Finland
Postencephalitic syndrome
+∞
10.4
10
*
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
+∞
10.4
10
*
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.2
10.4
21
41
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.0
10.3
22
45
C03CA01
ATC
furosemide; systemic
1.7
10.3
233
1547
N30.0
ICD-10 Finland
Acute cystitis
2.0
10.2
123
670
A28
ICPC
Limited function/disability NOS
1.9
10.2
136
768
R25.1
ICD-10 Finland
Tremor, unspecified
3.9
10.1
30
80
N05CF01
ATC
zopiclone; oral
1.7
10.0
244
1649
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
10.0
80
371
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
40.6
10.0
12
*
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.5
10.0
34
100
Z2446
NOMESCO Finland
Social worker
2.5
10.0
63
263
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.2
10.0
26
63
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
9.9
269
1871
L28
ICPC
Limited function/disability (L)
1.9
9.8
137
785
F03
ICD-10 Finland
Unspecified dementia
3.1
9.7
41
138
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
9.6
54
213
N06AX11
ATC
mirtazapine; oral
1.7
9.4
254
1760
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
9.4
106
564
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
9.4
213
1410
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
9.3
142
835
5CM18, ,
NOMESCO Finland
13.9
9.2
15
11
N06AB04
ATC
citalopram; systemic
1.8
9.2
160
981
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.6
9.2
53
212
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.6
9.1
30
86
R4130
NOMESCO Finland
Speech therapy
3.6
9.0
29
82
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
9.0
327
2434
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.0
8.9
19
39
JN4BD
NOMESCO Finland
Extensive body CT
2.1
8.9
84
418
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.4
8.8
62
272
J01DB01
ATC
cefalexin; oral
1.8
8.8
615
5348
B02.0
ICD-10 Finland
Zoster encephalitis
50.6
8.7
10
*
N05AX08
ATC
risperidone; systemic
2.2
8.6
78
381
N05AA02
ATC
levomepromazine; systemic
2.9
8.6
39
137
R1260
NOMESCO Finland
Evaluation of communicative skills
4.1
8.6
23
57
N05BA04
ATC
oxazepam; oral
1.7
8.4
197
1308
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.0
8.4
18
37
A87.8
ICD-10 Finland
Other viral meningitis
+∞
8.3
8
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
8.2
165
1051
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
6.6
8.2
20
31
J01MA12
ATC
levofloxacin; systemic
1.8
8.2
142
867
G40
ICD-10 Finland
Epilepsy
7.7
8.2
18
24
B34.9
ICD-10 Finland
Viral infection, unspecified
3.3
8.2
31
98
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.0
8.1
36
125
H02AB09
ATC
hydrocortisone; systemic
3.7
8.1
25
69
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.4
8.1
20
32
SPAT1254
SPAT
Administration of medicine
1.9
8.0
117
678
C07AB07
ATC
bisoprolol; oral
1.5
8.0
347
2667
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
8.0
84
435
N06AX16
ATC
venlafaxine; oral
1.9
7.9
106
598
J01MA02
ATC
ciprofloxacin; systemic
1.6
7.8
279
2050
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.8
7.8
39
145
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
15.2
7.7
12
8
N03AX11
ATC
topiramate; oral
3.5
7.7
26
76
G41.2
ICD-10 Finland
Complex partial status epilepticus
45.4
7.7
9
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
7.7
106
602
A02BC02
ATC
pantoprazole; systemic
1.5
7.6
481
3995
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
12.0
7.6
13
11
TK800
NOMESCO Finland
Hemodialysis
3.9
7.6
22
58
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
7.6
73
366
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.5
258
1875
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.8
7.5
36
131
A06AD11
ATC
lactulose; oral
1.8
7.2
112
660
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
7.2
66
325
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
7.1
84
453
R55
ICD-10 Finland
Syncope and collapse
1.9
7.1
88
483
ZXY02
NOMESCO Finland
Neuropsychologist
10.1
7.1
13
13
H02AB07
ATC
prednisone; oral
1.8
6.9
102
592
N03AX12
ATC
[U] gabapentin; oral
1.8
6.9
119
725
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
6.9
74
387
N99
ICPC
Neurological disease other
6.8
6.8
16
24
H02AB04
ATC
methylprednisolone; systemic
1.8
6.8
106
625
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
6.8
52
237
WX882
NOMESCO Finland
High dependency care
3.1
6.7
27
89
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
6.0
6.6
17
29
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
6.0
6.6
17
29
H3603, E103,
ICD-10 Finland
8.8
6.6
13
15
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
6.5
231
1683
F43.1
ICD-10 Finland
Post-traumatic stress disorder
3.2
6.5
25
80
N06AX21
ATC
duloxetine; oral
1.9
6.5
84
468
G05.1*B02.0
ICD-10 Finland
Zoster encephalitis
70.4
6.4
7
*
N02AA05
ATC
oxycodone; systemic
1.7
6.4
128
812
A10AC01
ATC
insulin (human); parenteral
2.0
6.4
65
333
WX002
NOMESCO Finland
Sedation and analgesia
1.7
6.3
135
871
G40.89
ICD-10 Finland
Other epilepsy
11.1
6.3
11
10
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.1
6.3
58
286
A10AB05
ATC
insulin aspart; parenteral
2.0
6.3
63
321
G05.1*B01.1
ICD-10 Finland
Varicella encephalitis
+∞
6.3
6
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.9
6.2
29
104
A69.2
ICD-10 Finland
Lyme disease
2.3
6.1
45
202
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.0
6.1
62
317
U08
ICPC
Urinary retention
3.8
6.1
18
48
G93.4
ICD-10 Finland
Encephalopathy, unspecified
12.6
6.1
10
8
N03AX23
ATC
brivaracetam; systemic
12.6
6.1
10
8
N02AX02
ATC
tramadol; systemic, rectal
1.5
6.1
300
2331

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
248
139
25.89
322.46
1.6
1.4
705.58
454.70
mg/l
6.72
238
132
229
107
30.09
320.82
1.6
1.5
—
—
—
0
0
206
51
54.86
307.65
1.3
1.3
—
—
—
0
0
244
123
28.63
307.65
1.6
1.4
3.86
3.77
mmol/l
0.31
227
116
195
123
20.92
237.05
1.7
1.4
46.15
10.77
e6/l
3.40
167
95
195
123
20.92
237.05
1.8
1.5
560.91
1008.66
e6/l
0.21
171
100
141
52
33.00
212.22
1.6
1.7
—
—
—
0
0
107
55
22.45
140.78
1.8
1.8
—
—
—
0
0
193
385
6.36
97.01
2.6
2.4
25.71
26.80
au/ml
—
7
29
177
349
6.29
89.62
1.5
1.3
62.83
50.84
au/ml
—
8
25
58
24
26.06
82.42
1.3
1.3
—
—
—
0
0
102
145
7.96
69.82
1.9
3.3
29.14
33.91
umol/l
0.91
84
131
358
1655
3.18
53.49
5.6
4.2
—
—
—
0
0
59
66
9.60
48.67
1.2
1.2
—
—
—
0
0
343
1801
2.64
37.00
3.2
2.1
207.29
290.54
u/l
0.62
329
1700
33
24
14.32
35.84
1.4
1.5
—
—
—
0
0
41
43
10.02
35.32
1.5
1.1
65.18
46.11
mg/l
0.77
36
34
211
937
2.73
31.01
2.4
2.1
30.01
29.66
s
0.34
204
906
33
35
9.81
28.13
2.2
1.4
—
—
—
0
0
437
2838
2.25
26.39
8.5
6.2
8.69
8.61
%
0.17
405
2681
435
2827
2.24
26.12
7.8
5.9
2.40
2.87
%
4.52
401
2666
510
3543
2.31
25.95
7.0
4.9
6.93
6.68
mmol/l
1.35
487
3294
173
771
2.61
24.67
8.2
6.2
1.01
1.05
mmol/l
1.19
160
713
421
2742
2.19
24.61
7.9
5.9
0.60
0.66
%
1.65
388
2578
198
943
2.48
24.53
3.7
3.5
0.80
0.82
mmol/l
1.40
181
885
458
3098
2.19
24.13
7.5
6.1
0.17
0.19
e9/l
2.34
398
2738
448
3007
2.18
24.04
7.3
5.8
0.04
0.04
e9/l
0.48
389
2614
438
2917
2.17
23.94
8.2
6.0
26.74
27.97
%
1.25
404
2759
433
2883
2.15
23.53
7.6
5.8
58.30
57.09
%
1.14
402
2731
445
2996
2.16
23.47
7.4
5.8
0.62
0.58
e9/l
2.23
385
2598
420
2783
2.13
22.88
16.6
14.8
1.28
1.27
inr
0.06
110
838
451
3086
2.12
22.37
7.7
5.9
1.84
1.98
e9/l
0.96
402
2747
120
473
2.82
21.59
3.9
2.6
9.56
10.64
g/l
1.98
112
437
125
511
2.73
20.95
9.9
7.8
8.00
9.76
mmol/l
2.79
115
485
539
4012
2.16
20.59
6.2
4.4
5072.10
2755.26
e6/l
—
10
68
231
1256
2.20
20.57
2.9
2.6
4.86
5.41
e6/l
0.23
208
1128
282
1659
2.11
20.48
3.7
3.1
0.33
0.43
e6/l
0.58
224
1232
450
3140
2.05
20.39
7.0
6.2
10.09
11.59
umol/l
4.10
426
2968
133
572
2.60
20.11
4.7
4.2
5.84
5.73
kpa
0.71
128
552
429
2957
2.02
19.95
9.6
7.0
1.21
1.21
mmol/l
0.42
369
2516
275
1618
2.09
19.84
3.6
3.0
—
—
—
0
0
31
19
16.94
19.77
1.3
1.0
1768.10
1444.37
miu/ml
0.54
31
19
131
569
2.57
19.37
4.8
4.3
1.64
1.68
mmol/l
0.04
115
459
409
2827
1.96
18.27
8.9
6.3
—
—
—
0
0
255
1498
2.05
18.18
5.2
3.9
88.25
89.62
%
0.37
244
1467
376
2538
1.94
17.89
6.2
4.9
34.37
35.62
g/l
3.99
352
2384
393
2698
1.94
17.72
9.3
6.2
1.21
1.21
mmol/l
0.44
363
2454
295
1839
1.98
17.69
3.9
3.0
—
—
—
0
0
209
1157
2.11
17.36
1.8
1.9
—
—
—
0
0
218
1227
2.09
17.32
3.2
2.9
529.85
551.44
mosm/kgh2o
0.73
191
1046
32
61
5.43
16.20
1.3
1.1
—
—
—
0
0
289
1837
1.92
16.01
4.1
3.2
31.79
82.30
e6/l
0.75
230
1394
107
465
2.51
15.65
3.5
2.9
65.98
66.74
g/l
0.39
94
424
467
3478
1.88
15.57
11.2
9.3
4.46
4.11
e9/l
2.14
411
3051
40
97
4.30
15.27
4.7
5.3
359.31
377.87
umol/l
0.33
35
86
112
510
2.40
14.78
7.8
8.4
—
—
—
0
0
319
2143
1.84
14.51
4.7
3.7
50.34
92.69
e6/l
1.24
244
1498
18
6
30.66
13.92
1.0
1.0
—
—
—
0
0
338
2335
1.80
13.84
5.4
3.7
30.48
41.53
ng/l
1.52
251
1612
191
1109
1.96
13.48
1.8
1.7
1138.52
1174.03
nmol/l
0.20
147
837
531
4212
1.85
13.47
6.0
4.2
—
—
—
0
0
567
4621
1.87
12.81
9.7
7.4
76.66
78.93
u/l
0.64
538
4330
58
204
2.99
12.71
2.6
1.4
0.22
0.23
g/l
0.73
52
197
112
558
2.18
11.86
2.0
1.9
371.18
373.78
nmol/l
0.05
107
513
21
36
5.97
11.85
1.0
1.0
345.86
273.43
ng/l
0.37
14
23
21
36
5.97
11.85
1.0
1.0
694.17
606.25
ng/l
0.29
12
24
275
1863
1.74
11.52
2.9
2.5
58.50
102.07
u/l
0.51
254
1731
286
1974
1.72
11.12
3.8
3.4
2.33
2.35
mmol/l
1.44
245
1751
57
214
2.80
11.11
2.6
1.4
1.10
1.18
g/l
0.82
52
205
291
2021
1.71
11.04
3.6
3.3
33.65
32.10
u/l
0.21
275
1928
36
103
3.62
10.99
1.2
1.1
—
12.98
—
0
9
230
1506
1.75
10.73
7.2
6.7
—
—
—
0
0
170
1017
1.86
10.71
3.2
2.7
1.53
1.06
e6/l
1.09
101
556
35
102
3.55
10.40
1.4
1.4
82.57
61.77
mmol/l
1.57
28
88
147
859
1.88
9.90
3.1
2.4
2.24
2.32
g/l
0.75
130
795
129
723
1.94
9.85
1.8
1.6
—
—
—
0
0
81
382
2.25
9.77
2.2
1.6
1.21
1.52
g/l
0.59
72
355
105
555
2.03
9.46
2.8
2.4
30.00
32.38
u/l
0.30
87
479
36
114
3.26
9.43
2.1
2.2
—
—
—
0
0
135
786
1.87
9.15
1.5
1.3
640.00
496.97
titre
0.38
35
165
252
1756
1.65
9.06
3.2
3.1
1346.96
1406.58
ng/l
0.11
211
1495
24
59
4.17
9.03
1.3
1.3
0.29
0.38
g/l
0.79
15
44
24
59
4.17
9.03
1.3
1.3
2.08
2.92
g/l
1.19
15
44
24
59
4.17
9.03
1.3
1.3
5.13
7.18
g/l
2.68
15
45
38
129
3.05
8.89
4.8
5.2
—
—
—
0
0
24
61
4.03
8.65
1.3
1.3
—
—
—
0
0
353
2697
1.57
8.52
13.6
9.4
0.00
0.00
e9/l
0.03
284
2203
136
811
1.82
8.51
3.2
2.5
21.18
22.84
%
0.82
110
700
251
1770
1.62
8.50
6.3
4.0
7.40
7.40
ph
0.11
50
328
18
23
7.99
8.40
1.1
1.7
—
—
—
0
0
267
1919
1.60
8.33
3.2
2.4
—
—
—
0
0
63
287
2.30
8.25
5.3
3.5
0.70
0.64
%
0.70
63
287
494
4099
1.58
8.12
4.0
3.1
55.13
46.93
u/l
1.13
459
3834
321
2420
1.56
8.09
2.3
2.0
90.74
94.20
pmol/l
0.67
175
1271
116
675
1.85
7.83
7.9
8.3
0.42
1.05
mmol/l
0.67
96
539
36
128
2.90
7.79
5.2
3.7
—
—
—
0
0
40
151
2.74
7.76
1.4
1.2
24.33
2.73
u/ml
—
6
16
40
152
2.72
7.66
1.3
1.2
8.77
12.82
u/ml
—
7
25
77
394
2.06
7.56
3.3
2.6
—
—
—
0
0
115
678
1.82
7.43
7.7
8.2
12.58
12.18
kpa
0.26
108
650
115
678
1.82
7.43
7.7
8.2
5.06
5.07
kpa
0.02
108
647
147
931
1.72
7.43
3.1
2.4
11.50
13.11
umol/l
2.15
130
864
81
426
2.01
7.38
4.5
3.9
7.41
7.39
ph
0.53
11
47
24
69
3.56
7.32
1.4
1.5
273.50
280.36
mosm/kgh2o
0.62
18
45
11
7
15.91
7.24
2.3
5.6
—
—
—
0
0
524
4460
1.55
7.23
5.3
4.0
13.82
11.79
mm/h
2.01
489
4109
30
101
3.05
7.15
1.3
1.6
0.46
0.82
g/l
1.32
21
81
57
265
2.24
7.13
1.5
2.0
1.74
1.50
g/l
0.96
48
234
81
432
1.98
7.10
4.5
3.9
5.13
5.10
kpa
0.08
74
414
313
2398
1.52
7.07
4.6
3.3
5.88
5.78
ph
0.23
21
185
115
688
1.79
7.07
3.7
2.8
1.86
1.80
%
0.21
101
622
52
235
2.30
6.96
2.2
2.0
0.68
2.94
ug/l
1.07
44
204
46
198
2.41
6.86
3.4
1.9
—
—
—
0
0
171
1151
1.63
6.80
4.2
3.7
82.04
294.88
ng/l
2.85
134
893
35
133
2.71
6.73
6.3
3.9
2.88
2.60
mmol/l
0.21
24
85
97
562
1.83
6.62
2.3
2.5
0.22
0.21
g/l
0.44
89
528
104
617
1.79
6.56
1.4
1.7
—
—
—
0
0
114
695
1.75
6.56
3.0
2.9
8.86
8.78
umol/l
0.01
94
610
215
1541
1.55
6.51
2.2
2.1
2.88
3.06
mg/l
0.61
181
1316
84
469
1.89
6.43
1.4
1.4
—
—
—
0
0
24
76
3.23
6.34
10.3
9.3
7.82
6.81
mmol/l
0.73
19
61
148
977
1.64
6.33
3.6
2.9
4.02
2.27
e6/l
0.71
82
518
29
105
2.83
6.11
4.3
3.2
52.72
57.90
%
1.05
29
105
177
1237
1.56
5.94
1.8
1.4
2.21
2.43
g/l
0.91
116
762
9
6
15.15
5.91
1.0
1.0
—
—
—
0
0
144
963
1.61
5.82
1.8
1.6
—
—
—
0
0
371
3024
1.44
5.75
5.1
3.6
0.00
0.01
estimate
0.80
80
551
367
2986
1.44
5.74
5.0
3.6
0.00
0.00
estimate
0.50
91
609
86
505
1.79
5.62
4.0
2.8
70.94
71.30
e9/l
0.03
65
393
207
1517
1.50
5.53
3.5
2.7
2526.06
6355.82
umol/l
0.88
184
1323
155
1071
1.56
5.43
3.3
3.1
2.45
2.45
mmol/l
0.42
132
955
36
155
2.39
5.41
1.5
2.3
12.26
11.93
mg/l
0.05
31
141
24
85
2.88
5.29
1.8
3.0
—
—
—
0
0
64
352
1.89
5.15
1.3
1.2
—
—
—
0
0
39
179
2.24
5.09
4.7
3.8
65.53
92.22
mg/l
0.28
31
142
39
179
2.24
5.09
4.7
3.8
30.65
31.37
mg/l
0.03
31
142
92
567
1.71
5.08
6.0
4.2
—
—
—
0
0
18
55
3.33
5.05
4.1
3.5
—
—
—
0
0
26
99
2.68
5.03
1.0
1.1
—
—
—
0
0
30
123
2.50
5.02
1.3
1.3
—
—
—
0
0
192
1411
1.48
5.00
1.7
1.5
21.22
20.72
nmol/l
0.17
167
1201
36
161
2.30
4.99
6.5
3.7
7.40
7.42
ph
0.77
36
140
38
174
2.25
4.99
4.7
3.8
3.34
1.94
ratio
—
5
21
31
130
2.44
4.95
4.3
4.1
—
—
—
0
0
362
2991
1.40
4.94
6.9
4.8
0.00
0.00
estimate
-0.00
86
571
75
440
1.78
4.92
5.1
4.8
0.06
0.11
%
0.22
32
138
197
1462
1.47
4.87
2.8
2.3
—
—
—
0
0
47
237
2.05
4.85
3.6
1.8
—
—
—
0
0
76
450
1.76
4.84
4.6
3.9
89.85
82.66
ng/l
0.24
59
406
37
171
2.22
4.76
3.3
2.5
—
—
—
0
0
19
63
3.07
4.70
1.6
1.4
59.54
58.64
%
0.03
13
47
110
725
1.60
4.69
1.9
1.6
—
—
—
0
0
42
206
2.10
4.67
1.3
1.3
—
—
—
0
0
323
2640
1.39
4.60
3.0
2.8
129.36
123.79
ug/l
0.18
294
2441
76
458
1.73
4.56
5.3
4.8
0.03
0.11
%
1.23
34
156
74
444
1.74
4.51
4.9
4.6
0.53
0.51
%
0.05
34
157
10
15
6.74
4.48
1.4
1.3
—
—
—
0
0
29
124
2.39
4.46
1.2
1.3
393.48
268.00
u/ml
0.59
21
68
184
1369
1.45
4.45
2.0
1.7
0.83
1.23
mg/l
3.01
145
1044
48
253
1.96
4.41
3.6
1.8
—
—
—
0
0
79
487
1.69
4.37
5.5
4.7
0.84
0.83
%
0.02
37
186
68
402
1.76
4.37
4.1
2.8
4.45
5.84
e9/l
0.67
58
331
48
254
1.95
4.36
3.6
1.7
—
—
—
0
0
16
50
3.25
4.35
1.3
1.1
—
—
—
0
0
298
2423
1.38
4.31
2.8
2.3
76.73
76.02
nmol/l
0.17
268
2158
48
255
1.94
4.31
3.7
1.7
—
—
—
0
0
18
61
3.00
4.30
1.2
1.3
—
—
—
0
0
25
102
2.50
4.25
1.1
1.1
—
—
—
0
0
126
877
1.52
4.23
2.2
2.0
—
—
—
0
0
35
167
2.15
4.19
1.3
1.2
—
—
—
0
0
20
75
2.71
4.02
2.6
1.7
90.59
90.26
%
0.12
20
75
22
87
2.57
3.99
1.5
1.5
—
—
—
0
0
28
126
2.27
3.87
3.7
2.5
16.01
15.79
%
0.11
14
68
235
1866
1.37
3.86
4.1
3.2
7.21
7.76
mmol/l
1.02
209
1583
75
473
1.65
3.83
9.2
3.8
1.22
1.23
mmol/l
0.22
66
412
9
15
6.06
3.82
3.9
1.6
—
—
—
0
0
80
516
1.61
3.74
2.7
2.5
4.62
7.25
ug/l
1.46
66
457
335
2820
1.33
3.72
3.2
2.6
—
—
—
0
0
58
344
1.74
3.71
2.5
3.2
4.12
4.58
pmol/l
3.19
50
304
39
204
1.96
3.69
3.5
2.5
10.01
10.58
g/l
0.28
32
182
18
67
2.73
3.68
2.3
2.6
—
—
—
0
0
46
255
1.86
3.67
3.8
1.6
—
—
—
0
0
165
1244
1.42
3.66
1.7
1.7
426.77
25462048.91
pmol/l
1.17
137
1029
657
6140
1.49
3.65
27.1
14.0
24.44
23.91
mg/l
0.16
594
4852
12
30
4.05
3.60
1.1
1.0
—
—
—
0
0
7
9
7.84
3.56
2.4
1.8
—
—
—
0
0
27
125
2.20
3.52
2.9
2.3
128.10
128.21
g/l
0.01
20
99
75
484
1.61
3.51
4.6
3.4
—
—
—
0
0
28
132
2.16
3.49
1.6
1.5
12962.86
12566.73
e6/l
0.02
22
98
214
1699
1.36
3.47
3.6
3.2
343.08
241.59
mg/l
0.14
145
1113
113
802
1.48
3.45
1.2
1.2
—
—
—
0
0
211
1675
1.36
3.41
4.8
3.2
—
—
—
0
0
42
234
1.84
3.32
9.5
4.3
—
—
—
0
0
79
524
1.57
3.30
4.6
3.5
—
—
—
0
0
24
109
2.24
3.28
6.4
4.7
62.58
61.95
%
0.04
24
109
13
39
3.37
3.23
4.3
3.6
—
—
—
0
0
12
34
3.57
3.20
1.1
1.0
—
—
—
0
0
52
316
1.69
3.09
4.9
4.0
—
—
—
0
0
505
4571
1.31
3.06
4.5
3.8
14.88
14.79
pmol/l
0.34
465
4128
8
16
5.04
3.05
1.0
1.6
—
—
—
0
0
13
46
2.86
2.93
1.2
1.5
1.56
1.27
promille
—
8
35
32
171
1.91
2.90
4.7
3.2
—
—
—
0
0
33
180
1.87
2.82
1.2
1.4
306.06
303.44
ug/g
0.02
17
109
178
2196
0.75
2.78
2.9
2.8
—
—
—
0
0
168
1327
1.34
2.76
5.8
3.9
1.02
1.02
kg/l
0.13
35
189
9
24
3.78
2.68
5.3
3.7
—
—
—
0
0
24
120
2.03
2.63
3.7
3.1
—
—
—
0
0
20
93
2.18
2.63
1.2
1.2
6.73
6.50
u/ml
0.02
11
42
658
6233
1.39
2.62
29.0
16.1
138.95
139.63
mmol/l
7.05
641
6056
103
759
1.41
2.59
2.3
2.3
171.13
127.40
ug/g
0.31
89
601
32
178
1.83
2.59
3.9
2.6
36.83
37.92
g/l
0.29
25
157
20
94
2.16
2.56
1.6
1.5
—
—
—
0
0
72
497
1.50
2.55
1.3
1.4
—
—
—
0
0
197
1617
1.29
2.44
5.6
3.8
0.00
0.01
estimate
0.88
78
557
658
6251
1.37
2.42
28.9
16.2
3.96
3.98
mmol/l
0.56
639
6059
6
12
5.03
2.40
1.2
1.4
—
—
—
0
0
216
1798
1.28
2.40
4.4
3.8
11.76
10.03
mg/mmol
0.22
144
1150
22
111
2.01
2.37
4.2
3.0
0.81
0.91
nmol/l
0.40
16
88
12
46
2.63
2.36
1.0
1.1
—
—
—
0
0
36
214
1.72
2.36
5.1
4.0
0.66
0.23
g/l
0.78
21
92
47
301
1.60
2.33
2.5
2.4
—
—
—
0
0
20
98
2.07
2.33
5.5
3.0
—
—
—
0
0
20
380
0.51
2.33
1.3
1.4
—
—
—
0
0
21
105
2.03
2.32
2.3
1.6
—
—
—
0
0
59
399
1.52
2.32
6.0
5.8
—
—
—
0
0
13
53
2.48
2.28
1.3
1.2
—
—
—
0
0
8
23
3.50
2.27
1.0
1.0
—
—
—
0
0
88
647
1.41
2.26
1.2
1.3
—
—
—
0
0
98
734
1.38
2.26
1.5
1.4
—
—
—
0
0
591
5549
1.28
2.22
5.4
4.6
1.86
2.12
mu/l
0.63
544
5066
6
14
4.31
2.15
2.2
2.2
23.68
17.10
umol/l
—
6
14
25
138
1.84
2.11
1.2
1.2
—
—
—
0
0
17
82
2.10
2.08
3.5
2.7
—
—
—
0
0
6
15
4.02
2.04
1.2
1.1
—
—
—
0
0
17
84
2.05
1.97
3.5
2.7
4.08
4.04
mmol/l
0.17
17
84
17
84
2.05
1.97
3.5
2.7
106.53
105.50
mmol/l
0.44
17
84
166
1370
1.27
1.95
4.6
3.6
—
—
—
0
0
6
16
3.77
1.94
1.0
1.0
—
—
—
0
0
28
165
1.72
1.93
1.3
1.2
—
89.17
—
0
12
204
1727
1.25
1.93
4.6
3.8
—
—
—
0
0
47
317
1.51
1.91
9.9
11.3
—
—
—
0
0
22
122
1.83
1.86
1.4
1.7
—
—
—
0
0
123
984
1.30
1.85
1.3
1.3
34.03
34.20
iu/ml
0.00
33
311
63
455
1.42
1.82
1.2
1.2
—
—
—
0
0
6
18
3.35
1.75
1.8
1.6
—
—
—
0
0
11
48
2.31
1.71
10.8
7.9
12.19
11.01
%
0.37
11
48
116
934
1.29
1.67
1.3
1.3
11.58
10.65
u/ml
0.05
42
367
451
4174
1.20
1.65
4.2
3.8
—
—
—
0
0
6
140
0.42
1.53
1.5
1.5
—
—
—
0
0
14
72
1.96
1.49
4.9
4.6
—
—
—
0
0
7
28
2.51
1.45
1.7
1.3
—
—
—
0
0
14
73
1.93
1.44
1.1
1.4
—
—
—
0
0
6
136
0.44
1.41
1.5
1.4
—
—
—
0
0
32
214
1.52
1.40
2.2
2.4
182.86
3198.72
u/l
—
8
89
12
60
2.02
1.38
5.0
2.4
—
—
—
0
0
5
17
2.95
1.36
1.2
1.4
—
—
—
0
0
25
159
1.59
1.36
1.9
2.3
63.78
89.66
ug/min
0.19
14
96
13
68
1.93
1.34
1.8
1.3
—
—
—
0
0
20
121
1.67
1.32
1.4
1.3
—
—
—
0
0
13
69
1.90
1.29
1.7
1.3
—
—
—
0
0
6
135
0.44
1.28
1.5
1.4
—
—
—
0
0
25
162
1.56
1.27
5.3
4.3
—
—
—
0
0
159
1371
1.20
1.25
1.3
1.3
3.25
1.51
u/ml
0.36
36
375
8
36
2.23
1.24
2.9
2.3
—
—
—
0
0
260
2340
1.17
1.24
2.2
2.1
—
—
—
0
0
660
6395
1.23
1.20
22.5
13.0
—
—
—
0
0
50
377
1.35
1.19
4.7
2.8
—
—
—
0
0
16
95
1.70
1.14
1.4
1.4
—
—
—
0
0
75
604
1.27
1.12
1.3
1.5
—
—
—
0
0
7
31
2.27
1.10
1.0
1.1
161.43
149.77
nmol/l
—
7
31
8
41
1.96
1.09
1.0
1.2
—
—
—
0
0
14
83
1.70
1.02
2.7
1.9
—
—
—
0
0
588
6080
0.86
1.00
5.0
4.8
2.63
2.74
mmol/l
2.08
533
5597
39
293
1.35
0.98
5.1
3.5
—
—
—
0
0
7
36
1.95
0.97
1.0
1.3
—
—
—
0
0
12
69
1.75
0.97
1.1
1.2
—
—
—
0
0
26
185
1.42
0.90
1.3
1.3
11.61
9.14
u/l
0.26
21
146
574
5927
0.87
0.86
4.5
4.3
1.36
1.45
mmol/l
5.42
517
5463
32
239
1.35
0.85
2.5
1.8
—
—
—
0
0
16
104
1.55
0.85
1.0
1.5
—
—
—
0
0
6
31
1.94
0.84
1.2
1.5
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
6.74
—
0
26
10
59
1.70
0.76
1.1
1.1
—
—
—
0
0
73
617
1.20
0.75
1.4
1.4
—
—
—
0
0
666
6515
1.17
0.75
14.7
10.0
26.85
26.51
u/l
0.20
643
6288
49
599
0.81
0.74
1.2
1.4
—
—
—
0
0
14
92
1.53
0.72
1.1
1.1
13.42
4.50
u/ml
—
9
51
9
57
1.59
0.71
1.1
1.1
—
—
—
0
0
5
26
1.93
0.70
1.8
1.0
29.60
68.13
mg/l
—
5
16
15
101
1.49
0.70
1.1
1.2
0.11
2.00
u/ml
—
9
53
9
58
1.56
0.70
6.2
2.1
13.17
13.06
%
—
9
58
5
27
1.86
0.68
1.2
1.1
192.20
187.65
mmol/24h
—
5
27
25
188
1.34
0.67
1.2
1.4
211.16
253.01
miu/ml
0.22
13
93
13
86
1.52
0.66
1.1
1.2
0.40
2.37
u/ml
—
8
38
10
62
1.62
0.65
1.6
1.4
—
—
—
0
0
5
29
1.73
0.64
3.6
6.3
—
—
—
0
0
5
29
1.73
0.64
2.4
2.8
66640.00
36103.62
ug/l
—
5
29
10
63
1.60
0.62
1.7
2.2
—
—
—
0
0
0
21
0.00
0.60
0.0
5.8
—
—
—
0
0
0
21
0.00
0.60
0.0
2.9
—
—
—
0
0
41
337
1.23
0.58
3.9
2.9
0.35
0.25
e6/l
0.30
41
327
26
203
1.29
0.56
1.2
1.2
—
—
—
0
0
583
5966
0.90
0.55
4.5
4.3
4.49
4.62
mmol/l
1.94
529
5528
85
751
1.15
0.55
1.2
1.3
—
—
—
0
0
19
142
1.35
0.55
5.1
2.5
—
—
—
0
0
9
60
1.51
0.54
3.0
2.9
—
—
—
0
0
6
38
1.58
0.54
2.2
2.0
—
—
—
0
0
548
5333
1.10
0.54
27.1
16.8
15.03
14.79
%
0.43
539
5246
23
293
0.78
0.53
1.5
1.6
—
—
—
0
0
10
66
1.52
0.52
2.1
1.6
—
—
—
0
0
9
63
1.43
0.52
1.2
1.2
—
—
—
0
0
19
145
1.32
0.49
1.8
1.7
3.35
6.26
iu/l
—
6
45
7
46
1.53
0.48
1.7
1.4
—
—
—
0
0
23
184
1.26
0.43
4.2
8.8
1.28
1.27
mmol/l
0.02
18
158
59
666
0.88
0.41
1.5
1.7
—
—
—
0
0
11
79
1.40
0.41
4.7
1.7
34.00
33.10
pg
0.28
11
79
17
132
1.29
0.40
1.6
1.2
—
—
—
0
0
68
609
1.13
0.39
3.3
4.4
3.93
30.21
ug/l
1.28
57
515
5
35
1.43
0.39
2.2
3.5
—
—
—
0
0
9
67
1.35
0.38
1.3
2.8
4.06
5.77
nmol/l
—
9
67
13
98
1.33
0.37
1.1
1.1
—
—
—
0
0
13
98
1.33
0.37
1.1
1.1
—
—
—
0
0
5
37
1.35
0.37
2.2
3.3
—
—
—
0
0
22
180
1.23
0.36
12.0
10.3
—
—
—
0
0
6
42
1.43
0.35
1.2
1.3
—
—
—
0
0
28
236
1.19
0.35
1.5
1.3
26.52
23.24
iu/l
0.17
21
191
20
242
0.82
0.33
2.0
2.5
—
—
—
0
0
47
418
1.13
0.32
1.3
1.4
—
—
—
0
0
514
5237
0.94
0.30
29.8
17.9
332.43
332.82
g/l
0.38
503
5200
12
93
1.29
0.30
3.8
2.8
—
—
—
0
0
7
55
1.28
0.30
1.0
1.2
—
—
—
0
0
8
63
1.27
0.28
1.1
1.2
—
—
—
0
0
567
5744
0.95
0.23
4.1
3.8
1.41
1.28
mmol/l
2.46
507
5266
21
241
0.87
0.21
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
9.00
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
11
89
1.24
0.21
1.2
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
5981.62
—
0
13
24
213
1.13
0.18
1.6
1.7
—
—
—
0
0
112
1169
0.95
0.17
3.6
2.9
0.68
0.76
ug/l
0.59
82
748
39
361
1.08
0.15
1.2
1.2
—
—
—
0
0
27
245
1.11
0.15
3.3
3.5
898.82
1587.90
u/ml
0.32
22
214
9
78
1.16
0.15
1.9
1.8
—
—
—
0
0
178
1732
1.04
0.14
1.5
1.4
—
—
—
0
0
161
1564
1.04
0.14
1.6
1.7
1.43
1.39
mmol/l
0.24
134
1310
22
199
1.11
0.13
1.5
1.8
45.86
38.41
nmol/l
0.65
22
188
26
239
1.09
0.12
1.3
1.2
—
—
—
0
0
558
5536
1.03
0.12
6.6
5.6
41.92
39.79
mmol/mol
4.20
513
5152
23
250
0.92
0.11
1.1
1.1
—
—
—
0
0
682
6847
0.96
0.09
35.6
20.5
39.27
40.28
%
3.59
645
6400
6
56
1.07
0.08
1.0
1.0
—
—
—
0
0
683
6855
0.97
0.08
35.3
20.5
133.14
135.82
g/l
4.99
669
6749
683
6852
0.97
0.07
35.1
20.4
4.44
4.51
e12/l
3.52
663
6662
683
6852
0.97
0.07
35.1
20.4
7.16
6.76
e9/l
4.94
664
6659
205
2021
1.02
0.07
4.8
4.8
2.57
2.53
ug/l
0.03
189
1805
10
89
1.13
0.07
1.2
1.2
—
—
—
0
0
683
6851
0.97
0.06
34.9
20.3
30.23
30.27
pg
0.17
669
6748
683
6850
0.97
0.06
35.0
20.3
90.81
90.80
fl
0.03
669
6747
683
6847
0.98
0.05
35.1
20.4
254.03
248.32
e9/l
1.26
666
6672
583
5845
0.99
0.03
4.8
4.4
6.16
5.93
mmol/l
2.74
522
5311
15
156
0.96
0.00
1.3
1.1
—
—
—
0
0
11
114
0.96
0.00
1.0
1.2
—
—
—
0
0
14
136
1.03
0.00
1.3
1.3
—
—
—
0
0
41
408
1.01
0.00
1.2
1.2
95.20
158.32
iu/ml
1.06
13
156
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
18.30
—
0
8

Mortality – FinRegistry

Association

Association between endpoint AB1_VIRAL_ENCEPHALITIS_NOS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_VIRAL_ENCEPHALITIS_NOS 2.464 [2.09, 2.9] < 0.001
Birth year 0.992 [0.98, 1.0] 0.08

During the follow-up period (1.1.1998 — 31.12.2019), 682 out of 2632 females with AB1_VIRAL_ENCEPHALITIS_NOS died.

Males

Parameter HR [95% CI] p-value
AB1_VIRAL_ENCEPHALITIS_NOS 2.368 [2.0, 2.8] < 0.001
Birth year 0.989 [0.98, 1.0] 0.027

During the follow-up period (1.1.1998 — 31.12.2019), 697 out of 2910 males with AB1_VIRAL_ENCEPHALITIS_NOS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_VIRAL_ENCEPHALITIS_NOS.

N-year risk Females Males
1 0.192% 0.38%
5 1.417% 2.691%
10 3.442% 7.213%
15 6.084% 13.363%
20 10.659% 21.966%

Relationships between endpoints

Index endpoint: AB1_VIRAL_ENCEPHALITIS_NOS – Viral encephalitis, not elsewhere classified/unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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