Pathological resorption of teeth

K11_RESORPTION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K03.3
  • Hospital discharge: ICD-10 K03.3
  • Hospital discharge: ICD-9 5214
  • Hospital discharge: ICD-8 5214
  • Cause of death: ICD-10 K03.3
  • Cause of death: ICD-9 5214
  • Cause of death: ICD-8 5214

3 out of 7 registries used, show all original rules.

1172

4. Check minimum number of events

None

1172

5. Include endpoints

None

1172

6. Filter based on genotype QC (FinnGen only)

1172

Control definitions (FinnGen only)

Control exclude
K11_ORAL

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8173 4096 4025
Only index persons 7807 3965 3842
Unadjusted period prevalence (%)
Whole population 0.11 0.12 0.11
Only index persons 0.15 0.15 0.15
Median age at first event (years)
Whole population 43.95 45.06 42.96
Only index persons 45.30 45.97 44.61

-FinnGen-

Key figures

All Female Male
Number of individuals 1172 649 523
Unadjusted period prevalence (%) 0.23 0.22 0.23
Median age at first event (years) 56.08 53.00 59.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
979
Matched controls
9791
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K03.39
ICD-10 Finland
Pathological resorption of teeth UNS
+∞
323.0
332
*
K03.30
ICD-10 Finland
Internal granuloma of pulp
+∞
323.0
536
*
EB1AA
NOMESCO Finland
Tooth X-ray examination
17.6
288.6
863
2907
SAA01
NOMESCO Finland
Simple examination of mouth
16.9
215.3
911
4328
K05.30
ICD-10 Finland
Periodontitis complex
+∞
211.3
195
*
SAA02
NOMESCO Finland
Basic examination of mouth
9.1
183.8
826
3648
SAA03
NOMESCO Finland
Extended examination of mouth
7.6
183.1
609
1739
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
7.6
181.6
596
1663
K03.3
ICD-10 Finland
Pathological resorption of teeth
+∞
176.5
164
*
WX110
NOMESCO Finland
Local anesthesy
10.5
174.6
877
4399
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
+∞
173.2
161
*
K02.1
ICD-10 Finland
Caries of dentine
7.2
167.1
755
3119
SFA10
NOMESCO Finland
Fillning on one surface of tooth
7.0
166.7
733
2912
EBA00
NOMESCO Finland
Extraction of tooth
6.4
142.8
493
1340
K04.5
ICD-10 Finland
Chronic apical periodontitis
7.4
139.7
400
839
EBA10
NOMESCO Finland
Surgical removal of tooth
14.5
137.9
247
223
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
5.8
137.2
730
3270
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
6.0
135.9
503
1468
K05.31
ICD-10 Finland
Periodontitis pronounced
+∞
135.6
127
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
5.6
126.3
488
1465
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
5.3
124.6
558
1971
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
16.2
123.8
209
161
WX290
NOMESCO Finland
Other blockade of nerve
4.9
115.8
590
2325
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
4.8
115.8
638
2727
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
4.4
103.4
591
2506
SDA02
NOMESCO Finland
Parodonthologic therapy
4.7
98.0
431
1391
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
5.6
95.6
329
807
Z01.2
ICD-10 Finland
Dental examination
4.2
95.0
531
2141
WZA90
NOMESCO Finland
Other doctors statement
5.2
87.5
320
829
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
3.9
82.8
486
1971
K05.32
ICD-10 Finland
Periodontitis NOS
+∞
80.3
76
*
K05.1
ICD-10 Finland
Chronic gingivitis
+∞
79.2
75
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
4.3
78.2
359
1153
D82
ICPC
Teeth/gum disease
3.8
77.1
440
1714
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
4.2
73.4
340
1089
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
50.1
72.2
87
19
KMAK
NOMESCO Finland
NA
3.4
71.3
584
2969
EBA05
NOMESCO Finland
Complicated extraction of tooth
4.9
70.3
268
703
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
3.9
61.9
305
1008
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
13.0
61.7
112
96
SFA40
NOMESCO Finland
Replacement of krone of tooth
4.2
60.4
268
803
SAA04
NOMESCO Finland
Special inverstigation of mouth
13.9
59.6
105
84
K05.18
ICD-10 Finland
Chronic gingivitis
+∞
57.9
55
*
D19
ICPC
Teeth/gum symptom/complaint
3.6
57.6
319
1148
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
5.4
56.4
187
411
K03.64
ICD-10 Finland
Dental calculus supragingival
3.5
55.6
328
1238
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
106.4
55.5
60
6
K05.3
ICD-10 Finland
Chronic periodontitis
+∞
52.6
50
*
K03.00
ICD-10 Finland
Approximal wear
69.6
51.8
59
9
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
4.9
51.6
188
456
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
29.6
51.1
69
25
SGC00
NOMESCO Finland
Local medication of root channels of tooth
5.1
50.9
176
403
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
5.9
50.5
153
300
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
18.3
49.8
78
46
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
4.0
48.5
223
675
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
3.2
47.7
321
1307
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
6.2
46.7
134
244
SBB10
NOMESCO Finland
Teeth copy
7.7
46.7
113
162
SGB30
NOMESCO Finland
Other demanding filling of root channel of tooth
4.4
45.4
180
472
SDA01
NOMESCO Finland
Simple parodonthologic therapy
3.2
45.0
286
1109
K01.0
ICD-10 Finland
Embedded teeth
+∞
44.1
42
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
9.1
44.0
96
116
EBB10
NOMESCO Finland
Insertion of dental implant
65.7
43.6
50
8
SGA01
NOMESCO Finland
Tooth opening as first aid
3.7
43.3
214
683
K03.31
ICD-10 Finland
Resorption of teeth (external)
+∞
43.0
41
*
K04.1
ICD-10 Finland
Necrosis of pulp
4.7
41.1
151
364
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
3.1
40.4
274
1102
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
10.9
39.9
78
77
EMAK
NOMESCO Finland
NA
12.9
39.0
70
58
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
12.9
39.0
70
58
SGA05
NOMESCO Finland
Very demanding and lengthy opening and dilatation of root canal of tooth
6.2
38.3
108
191
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
+∞
37.7
36
*
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
4.5
37.3
141
349
-1
NOMESCO Finland
NA
2.6
37.2
360
1788
K05.22
ICD-10 Finland
Acute pericoronitis
+∞
36.7
35
*
SGA03
NOMESCO Finland
Demanding opening and dilatation of root canal of tooth
4.5
36.1
136
335
SGA04
NOMESCO Finland
Very demanding opening and dilatation of root canal of tooth
4.1
35.6
151
416
K02.0
ICD-10 Finland
Caries limited to enamel
4.0
34.4
150
423
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
4.6
32.9
123
299
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
18.3
31.7
49
28
EBB15
NOMESCO Finland
Insertion of dental implant abutment
88.0
30.9
34
*
K03.66
ICD-10 Finland
Tooth plaque
7.4
30.8
75
108
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
159.8
29.8
31
*
ECA50
NOMESCO Finland
Parodontal operation
149.2
27.8
29
*
SXC03
NOMESCO Finland
Other oral or dental procedure
48.6
27.6
33
7
VALMI
NOMESCO Finland
NA
2.5
27.2
248
1156
SFA00
NOMESCO Finland
Small filling
3.4
26.5
141
465
SXC05
NOMESCO Finland
Other oral or dental procedure
5.2
25.7
82
168
EB1AA
SPAT
NA
5.8
24.9
72
131
K08.80
ICD-10 Finland
Toothache NOS
4.4
24.5
92
224
K03.0
ICD-10 Finland
Excessive attrition of teeth
47.9
23.4
28
6
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
53.3
22.2
26
5
SFC92
NOMESCO Finland
Other demanding adjuvant procedure of filling therapy
4.7
22.1
77
174
K08.3
ICD-10 Finland
Retained dental root
5.2
21.8
69
140
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
20.6
21.8
32
16
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
3.7
21.4
98
285
K04.62
ICD-10 Finland
Periradicular abscess with fistula to mouth
9.7
21.2
43
46
K02.2
ICD-10 Finland
Caries of cementum
7.5
21.0
50
70
SDA05
NOMESCO Finland
Very demanding and lengthy parodonthologic therapy
6.0
21.0
59
104
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.4
21.0
107
340
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
24.0
20.0
28
12
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
24.0
20.0
28
12
K05.0
ICD-10 Finland
Acute gingivitis
+∞
19.9
19
*
SGB20
NOMESCO Finland
Filling of root of tooth with 2 root channels
4.1
19.7
79
205
ECB00
NOMESCO Finland
Suture of gingiva
7.6
19.6
46
63
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.9
19.6
84
231
SGC10
NOMESCO Finland
Covering pulpa of tooth
3.1
19.4
112
389
K05.39
ICD-10 Finland
Periodontitis UNS
+∞
18.8
18
*
K05.08
ICD-10 Finland
Another acute gingivitis
+∞
18.8
18
*
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
3.6
18.1
84
248
K07.60
ICD-10 Finland
Snapping jaw
6.2
18.0
49
83
F45.8
ICD-10 Finland
Other somatoform disorders
3.9
18.0
75
202
K04.7
ICD-10 Finland
Periapical abscess without sinus
4.9
17.8
59
127
K01.16
ICD-10 Finland
Retained molar with obstruction in the upper jaw
+∞
17.8
17
*
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
3.3
17.5
90
288
J01CE02
ATC
phenoxymethylpenicillin; oral
1.8
17.2
658
5181
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
11.8
17.1
31
27
SDC10
NOMESCO Finland
Parodontological fixation
32.1
17.1
22
7
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
64.4
16.8
19
*
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
7.3
16.7
40
57
K03.11
ICD-10 Finland
Abrasion dentifrice of teeth
35.7
16.7
21
6
EBA40
NOMESCO Finland
Excision of apex of root of tooth
28.1
16.5
22
8
SDA
NOMESCO Finland
Treatment of periodontitis and gingival lesions
172.7
16.5
17
*
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
17.1
16.1
25
15
K04.0
ICD-10 Finland
Pulpitis
2.9
15.8
103
386
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
+∞
15.7
15
*
K05.38
ICD-10 Finland
Other chronic periodontitis
+∞
15.7
15
*
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
3.9
15.6
65
175
SGC20
NOMESCO Finland
Correction of rooth channel perforation or inside resorption through rooth channel of tooth
162.4
15.5
16
*
SPC01
NOMESCO Finland
Fixed dental crown
13.3
15.2
26
20
S02.51
ICD-10 Finland
Fracture of tooth, open
2.9
15.2
95
346
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
8.3
15.1
33
41
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
45.7
15.1
18
*
WX110
SPAT
NA
4.5
15.0
53
122
K10.3
ICD-10 Finland
Alveolitis of jaws
5.0
14.8
47
97
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
7.9
14.7
33
43
ECA55
NOMESCO Finland
Complicated parodontal operation
152.1
14.5
15
*
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
2.7
14.5
103
408
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
7.5
14.3
33
45
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
4.8
13.8
46
100
K03.18
ICD-10 Finland
Other abrasion of the teeth
76.2
13.6
15
*
S02.54
ICD-10 Finland
Fracture of both the crown and the root
5.1
13.5
42
85
EB1MA
NOMESCO Finland
Cephalometry with X-ray
6.6
13.5
34
53
K04.09
ICD-10 Finland
Pulpit UNS
4.2
13.3
50
123
SPA02
NOMESCO Finland
Preparation for dental prosthetics
10.2
13.0
25
25
SFC00
NOMESCO Finland
Pillar of fillings material
5.8
12.9
36
64
N02BE01
ATC
paracetamol; systemic, rectal
1.8
12.9
778
6685
K03.08
ICD-10 Finland
Other wear and tear of the teeth
50.7
12.9
15
*
HMAK
NOMESCO Finland
NA
2.4
12.8
111
490
SBA00
NOMESCO Finland
Microbiological examinations
8.0
12.7
28
36
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
70.8
12.6
14
*
K05
ICD-10 Finland
Gingivitis and periodontal diseases
+∞
12.5
12
*
EBA00
SPAT
NA
9.5
12.5
25
27
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
4.1
12.5
48
121
ECA70
NOMESCO Finland
Regenerative parodontal operation or gingiva and alveolus transplantation
131.5
12.5
13
*
K03.09
ICD-10 Finland
Abrasion of the teeth UNS
131.5
12.5
13
*
SXA20
NOMESCO Finland
Local application of medicine to mouth
4.0
12.4
49
127
SPB30
NOMESCO Finland
Temporary partial teeth prothesis
38.0
12.2
15
*
P01AB01
ATC
metronidazole; oral, rectal
1.7
12.2
328
2233
SPC35
NOMESCO Finland
Production and attachment of single tooth bridge
10.2
12.0
23
23
K05.20
ICD-10 Finland
Periodontal abscess without fistula
+∞
11.5
11
*
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
121.3
11.4
12
*
EEC05
NOMESCO Finland
Le Fort I osteotomy
121.3
11.4
12
*
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
6.2
11.4
30
50
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
2.9
11.2
66
234
SPB20
NOMESCO Finland
Temporary bridge between two or more teeth
25.3
11.2
15
6
K07.13
ICD-10 Finland
Retrognaty, mandibular
25.3
11.2
15
6
SPF40
NOMESCO Finland
Removal and reattachment with cement of tooth crone or short bridge
8.7
11.1
23
27
S02.53
ICD-10 Finland
Fracture of tooth root
6.4
11.0
28
45
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
43.8
10.9
13
*
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
60.6
10.6
12
*
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
11.4
10.6
19
17
K05.2
ICD-10 Finland
Acute periodontitis
+∞
10.4
10
*
K07.14
ICD-10 Finland
Retrognaty, maxillary
+∞
10.4
10
*
K05.09
ICD-10 Finland
Acute gingivitis, UNS
+∞
10.4
10
*
K05.21
ICD-10 Finland
Periodontal abscess with fistula
+∞
10.4
10
*
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
12.2
10.4
18
15
EB1WA
NOMESCO Finland
NA
32.9
10.3
13
*
K07.23
ICD-10 Finland
Deep bite
5.8
10.3
28
49
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
14.7
10.0
16
11
K00.00
ICD-10 Finland
Hypodontia
14.7
10.0
16
11
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
16.9
9.9
15
9
SPC30
NOMESCO Finland
Tooth bridge attacment with resins
20.2
9.8
14
7
K04.9
ICD-10 Finland
Other and unspecified diseases of pulp and periapical tissues
10.8
9.8
18
17
EFA50
NOMESCO Finland
Excision of cyst of jaws
55.5
9.7
11
*
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.2
9.7
103
503
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
+∞
9.4
9
*
K03.19
ICD-10 Finland
Abrasion of the teeth UNS
+∞
9.4
9
*
L01
ICPC
Neck symptom/complaint
2.0
9.3
117
610
J01CA04
ATC
amoxicillin; systemic
1.6
9.3
754
6607
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
5.0
9.2
28
57
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
6.0
9.1
24
41
SPF41
NOMESCO Finland
Repair of dental crown, bridge or implant structure, standard
10.1
9.0
17
17
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
6.6
9.0
22
34
K03.1
ICD-10 Finland
Abrasion of teeth
18.8
8.9
13
7
SDC30
NOMESCO Finland
Strong parodontological fixation of 2-3 teeth
18.8
8.9
13
7
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
24.2
8.9
12
5
A98
ICPC
Health maint/preventive medicine
2.5
8.9
941
8887
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
8.0
8.9
19
24
K02
ICD-10 Finland
Dental caries
2.7
8.8
60
233
EB1SA
SPAT
NA
4.1
8.8
33
83
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
5.7
8.8
24
43
WX290
SPAT
NA
4.6
8.7
29
65
Z48.8
ICD-10 Finland
Other specified surgical follow-up care
14.2
8.7
14
10
TUPEI
NOMESCO Finland
NA
3.8
8.7
35
94
K03.2
ICD-10 Finland
Erosion of teeth
7.7
8.7
19
25
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
7.7
8.7
19
25
EBA15
NOMESCO Finland
Extraction of large number of teeth
5.3
8.6
25
48
SPE02
NOMESCO Finland
Metal-framed partial denture
11.7
8.6
15
13
K04.00
ICD-10 Finland
Hyperemia of pulp
3.4
8.5
40
122
SAAPA
NOMESCO Finland
NA
20.2
8.5
12
6
ECB20
NOMESCO Finland
Oral alveoplasty
20.2
8.5
12
6
M79.1
ICD-10 Finland
Myalgia
2.0
8.4
105
547
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
90.8
8.4
9
*
SDA10
NOMESCO Finland
Parodonthologic therapy of advnaced and complicated changes of alveolar bone
90.8
8.4
9
*
S18
ICPC
Laceration/cut
1.5
8.3
328
2415
K05.28
ICD-10 Finland
Another acute periodontitis
+∞
8.3
8
*
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
+∞
8.3
8
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
8.3
182
1152
K04.08
ICD-10 Finland
Other specified pulpit
2.7
8.1
55
213
SPC36
NOMESCO Finland
Direct fibre-reinforced dental bridge
11.8
8.1
14
12
L17
ICPC
Foot/toe symptom/complaint
1.7
8.1
195
1268
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
8.0
308
2256
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
4.8
8.0
25
53
K07.24
ICD-10 Finland
Open bite
13.1
7.9
13
10
K03.29
ICD-10 Finland
Erosion of teeth occupational
13.1
7.9
13
10
K08.88
ICD-10 Finland
Other specified disorders of teeth and supporting structures
8.5
7.8
16
19
K03.88
ICD-10 Finland
Other specified diseases of hard tissues of teeth
4.9
7.8
24
50
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
7.0
7.8
18
26
SPF10
NOMESCO Finland
Demanding repatation of teeth prosthesis
7.5
7.7
17
23
S21
ICPC
Skin texture symptom/complaint
2.0
7.7
99
522
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
8.1
7.6
16
20
EB1CA
SPAT
NA
18.5
7.6
11
6
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
6.8
7.6
18
27
L15
ICPC
Knee symptom/complaint
1.7
7.5
153
947
S03.22
ICD-10 Finland
Exarticulation of tooth
80.6
7.4
8
*
SJC00
NOMESCO Finland
Bracket with fixed attachment
80.6
7.4
8
*
SPC08
NOMESCO Finland
Implant crown
80.6
7.4
8
*
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
11.0
7.3
13
12
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
5.0
7.3
22
45
K03.5
ICD-10 Finland
Ankylosis of teeth
+∞
7.3
7
*
SGC30
NOMESCO Finland
Correction of rooth channel perforation or inside resorption through rooth channel of tooth, demanding
+∞
7.3
7
*
SPB10
NOMESCO Finland
Production of temporary crone to tooth
15.9
7.2
11
7
H01
ICPC
Ear pain/earache
2.0
7.1
87
450
SPA40
NOMESCO Finland
Precision impression for dental prosthesis
10.1
7.0
13
13
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
7.0
376
2939
N01
ICPC
Headache
2.0
6.9
92
493
K13.78
ICD-10 Finland
Other change in the oral mucosa
7.6
6.9
15
20
L82
ICD-10 Finland
Seborrhoeic keratosis
1.8
6.8
117
686
K07.61
ICD-10 Finland
Cracking jaw joint
8.3
6.8
14
17
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
5.4
6.8
19
36
S02.52
ICD-10 Finland
Tooth fracture to pulp
5.7
6.8
18
32
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
40.3
6.8
8
*
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
40.3
6.8
8
*
A97
ICPC
No disease
1.8
6.7
112
648
H29
ICPC
Ear symptom/complaint other
2.1
6.6
75
376
SPA50
NOMESCO Finland
Determination of bite and dental arch location
10.1
6.5
12
12
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
6.9
6.5
15
22
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.5
213
1491
SPE00
NOMESCO Finland
Fitting and preparation of metal structure partial teeth prosthesis
6.2
6.5
16
26
KAY60
NOMESCO Finland
NA
5.7
6.5
17
30
R05
ICPC
Cough
1.6
6.5
171
1138
R74
ICPC
Upper respiratory infection acute
1.5
6.4
239
1723
N03AX16
ATC
pregabalin; oral
1.6
6.4
169
1119
N03AX12
ATC
gabapentin; oral
1.8
6.4
106
611
T84.62
ICD-10 Finland
Osteitis associated with dental implants
70.2
6.4
7
*
SPA47
NOMESCO Finland
Precision impression for denture
7.5
6.4
14
19
SCA03
NOMESCO Finland
Preventive oral health care, extensive
2.7
6.4
41
154
L12
ICPC
Hand/finger symptom/complaint
1.8
6.4
116
693
L02
ICPC
Back symptom/complaint
2.1
6.4
73
369
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.4
6.3
51
219
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
6.3
165
1093
K05.6
ICD-10 Finland
Periodontal disease, unspecified
+∞
6.3
6
*
SGC50
NOMESCO Finland
Closure of open top of rooth of tooth
+∞
6.3
6
*
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
+∞
6.3
6
*
K07.10
ICD-10 Finland
Asymmetry of jaw
+∞
6.3
6
*
SPB06
NOMESCO Finland
Production of temporary clinic-made tooth- or implant-retained crown or bridge unit
26.8
6.2
8
*
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
26.8
6.2
8
*
C07AA05
ATC
propranolol; systemic
1.6
6.2
155
1014
R21
ICPC
Throat symptom/complaint
1.6
6.2
168
1121
SAALT
NOMESCO Finland
NA
5.4
6.2
17
32
M79.6
ICD-10 Finland
Pain in limb
1.5
6.2
266
1977
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
6.1
836
7714
Z01.9
ICD-10 Finland
Special examination, unspecified
2.5
6.1
46
191
K03.80
ICD-10 Finland
Irradiated enamel
2.7
6.1
39
147
K04.6
ICD-10 Finland
Periapical abscess with sinus
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
809
6679
1.68
14.67
8.9
6.7
78.3
77.5
u/l
0.18
778
6304
451
3254
1.63
13.85
1.9
1.8
105.9
94.9
pmol/l
3.86
235
1756
567
4329
1.60
13.74
7.1
5.7
10.8
11.7
umol/l
1.16
545
4130
472
3451
1.62
13.69
2.1
2.0
—
—
—
0
0
840
7068
1.67
13.48
4.2
3.7
14.8
14.7
pmol/l
0.34
772
6477
399
2815
1.63
13.29
7.4
5.4
—
—
—
0
0
966
8492
1.78
12.62
5.1
4.3
1.9
2.1
mu/l
0.51
898
7849
469
3507
1.56
11.91
2.6
2.1
75.9
74.8
nmol/l
0.40
435
3205
1047
9504
1.95
11.40
17.1
12.8
139.8
139.7
mmol/l
0.63
1023
9234
431
3206
1.54
10.98
9.6
7.7
1.3
1.2
inr
0.35
108
943
1048
9543
1.93
10.91
17.4
12.9
4.0
4.0
mmol/l
0.58
1023
9258
467
3544
1.53
10.80
7.9
5.4
1.2
1.2
mmol/l
1.27
426
3232
1099
10187
2.27
10.76
11.7
8.7
26.2
26.9
u/l
0.48
1070
9848
623
5053
1.50
10.31
5.9
4.3
6.5
6.7
mmol/l
1.03
579
4681
536
4219
1.50
10.25
7.7
5.2
56.8
56.9
%
0.08
505
3972
265
1787
1.62
10.18
1.6
1.5
21.7
20.6
nmol/l
0.38
226
1545
553
4386
1.49
10.16
7.8
5.2
0.6
0.6
e9/l
0.53
491
3804
554
4400
1.49
10.08
7.8
5.2
0.0
0.0
e9/l
0.25
490
3820
524
4140
1.48
9.65
8.4
5.6
8.8
8.5
%
0.79
495
3896
769
6557
1.50
9.64
4.5
3.6
11.3
10.9
mm/h
0.31
721
6095
520
4115
1.47
9.43
7.9
5.3
2.9
2.9
%
0.01
488
3848
565
4550
1.47
9.33
8.4
5.5
0.2
0.2
e9/l
0.43
510
4008
507
3998
1.47
9.33
7.9
5.4
0.7
0.7
%
0.01
481
3747
538
4293
1.47
9.31
7.9
5.4
28.7
28.4
%
0.22
505
4027
564
4545
1.46
9.26
7.9
5.3
2.2
2.0
e9/l
0.53
505
4028
499
3942
1.46
9.00
9.0
5.9
1.2
1.2
mmol/l
0.66
426
3324
1029
9439
1.74
8.78
15.1
11.3
22.6
23.3
mg/l
0.30
818
7191
718
6119
1.45
8.41
4.8
3.7
—
—
—
0
0
365
2742
1.48
8.38
2.9
3.1
2.3
2.4
mmol/l
0.12
322
2445
616
5107
1.43
8.37
10.5
8.0
4.0
4.0
e9/l
0.15
559
4470
157
970
1.71
8.34
1.7
1.4
—
—
—
0
0
104
567
1.92
8.34
4.0
3.0
3.5
4.2
e9/l
2.24
81
460
1083
10116
1.93
8.29
17.2
13.0
78.2
75.3
umol/l
1.67
1083
10111
205
1361
1.61
8.25
1.7
1.7
1051.9
1198.7
nmol/l
1.34
151
1041
194
1271
1.63
8.24
3.2
2.9
0.8
0.8
mmol/l
0.09
179
1195
447
3506
1.44
8.15
6.3
4.4
36.3
35.9
g/l
0.98
424
3284
1078
10091
1.85
7.65
14.0
10.7
—
—
—
0
0
180
1179
1.62
7.62
1.5
1.3
519.1
487.9
titre
0.11
45
229
348
2631
1.46
7.60
3.2
2.4
58.1
58.4
u/l
0.03
327
2458
97
547
1.84
7.03
5.1
3.3
97.3
81.2
ng/l
0.94
87
484
1137
10884
2.50
7.01
22.5
16.5
90.6
90.5
fl
0.19
1123
10727
1137
10884
2.50
7.01
22.4
16.5
30.2
30.2
pg
0.12
1124
10725
676
5798
1.39
7.00
4.6
3.9
1403.4
1940.0
e6/l
0.13
16
87
160
1039
1.63
7.00
7.5
4.5
1.0
1.0
mmol/l
0.06
147
968
1137
10885
2.49
6.99
22.5
16.5
4.5
4.6
e12/l
0.37
1113
10582
1136
10874
2.46
6.94
22.5
16.6
251.3
252.2
e9/l
0.17
1108
10599
1137
10889
2.48
6.91
22.6
16.6
6.7
6.7
e9/l
0.23
1111
10583
1137
10889
2.48
6.91
22.7
16.6
136.5
136.9
g/l
0.35
1124
10726
181
1231
1.56
6.50
3.0
2.2
12.9
14.0
umol/l
1.08
166
1137
977
8996
1.52
6.50
4.4
4.0
5.8
5.9
mmol/l
0.15
901
8292
274
2041
1.45
6.31
1.3
1.2
1.1
1.9
u/ml
0.80
71
532
169
1141
1.56
6.26
2.2
1.9
—
—
—
0
0
300
2276
1.43
6.25
1.7
1.6
1.5
1.4
mmol/l
0.81
257
1926
165
1112
1.56
6.16
2.4
2.4
170.6
121.5
ug/g
0.46
127
903
158
1056
1.57
6.12
3.2
2.2
22.5
24.5
%
1.01
135
901
167
1132
1.55
6.08
3.0
2.1
2.3
2.4
g/l
0.48
152
1043
117
727
1.68
6.08
3.4
2.3
0.2
0.2
g/l
0.05
111
684
278
2092
1.43
6.03
5.1
4.0
—
—
—
0
0
119
752
1.65
5.80
4.1
3.8
—
—
—
0
0
71
386
1.89
5.79
2.4
2.2
—
—
—
0
0
922
8456
1.42
5.68
5.6
5.0
38.6
39.2
mmol/mol
1.44
865
7902
485
4039
1.34
5.59
3.3
2.6
115.1
114.1
ug/l
0.04
447
3770
289
2238
1.39
5.24
2.7
2.3
1313.0
6757.6
umol/l
3.77
255
1987
266
2033
1.40
5.21
2.5
2.1
3.1
2.9
mg/l
0.65
239
1720
109
696
1.62
5.11
9.5
5.6
9.6
8.8
mmol/l
0.52
104
661
96
595
1.67
5.06
1.8
2.2
65.3
67.0
g/l
1.29
87
552
126
838
1.56
4.99
2.3
2.5
1.6
1.8
%
1.50
116
748
300
2355
1.37
4.97
4.7
3.4
—
—
—
0
0
1014
9525
1.48
4.95
4.9
4.4
2.8
2.8
mmol/l
0.03
949
8880
237
1793
1.40
4.91
1.6
1.4
2.5
2.4
g/l
0.28
150
1138
155
1092
1.48
4.70
1.9
1.5
—
—
—
0
0
18
58
3.14
4.65
2.8
2.3
1.3
1.1
e9/l
—
8
30
272
2126
1.36
4.60
9.3
5.9
—
—
—
0
0
108
707
1.58
4.58
1.4
1.4
—
—
—
0
0
290
2292
1.35
4.56
5.3
3.4
7.4
7.4
ph
0.01
55
469
999
9397
1.43
4.46
4.5
4.0
4.7
4.7
mmol/l
0.62
942
8811
30
130
2.34
4.46
1.3
1.6
—
—
—
0
0
12
30
4.03
4.44
1.4
1.6
—
—
—
0
0
9
12
7.55
4.36
4.3
3.2
—
—
—
0
0
101
661
1.58
4.30
3.5
2.4
10.9
10.5
g/l
0.30
95
596
170
1241
1.43
4.28
2.0
2.0
30.7
29.6
s
0.56
164
1199
18
62
2.93
4.18
1.1
1.1
—
—
—
0
0
247
1929
1.36
4.16
1.7
1.6
1.0
1.1
mg/l
0.33
190
1489
960
9001
1.37
4.10
4.0
3.6
1.3
1.3
mmol/l
0.01
900
8389
992
9352
1.40
4.08
4.5
3.9
1.4
1.5
mmol/l
0.44
930
8727
106
712
1.54
4.04
1.4
1.4
—
—
—
0
0
364
3017
1.30
4.03
3.7
3.2
47.1
82.1
e6/l
0.80
259
2090
169
1246
1.42
4.03
3.1
2.6
4.9
2.3
e6/l
1.05
105
651
339
2789
1.30
3.96
2.7
2.1
—
—
—
0
0
77
482
1.64
3.95
1.2
1.2
—
—
—
0
0
136
968
1.46
3.92
1.5
1.6
—
—
—
0
0
308
2505
1.31
3.91
3.3
2.9
26.8
98.5
e6/l
1.75
242
1917
115
793
1.50
3.89
2.3
1.9
348.3
383.2
nmol/l
1.10
108
735
56
323
1.77
3.87
1.5
1.8
1.5
1.5
g/l
0.23
48
273
496
4295
1.27
3.84
4.4
3.8
—
—
—
0
0
147
1069
1.43
3.78
1.3
1.3
—
—
—
0
0
465
4008
1.27
3.71
11.6
8.1
0.0
0.0
e9/l
2.31
385
3292
45
248
1.85
3.62
1.5
1.4
268.1
281.9
ug/g
0.14
21
139
291
2371
1.30
3.62
2.9
2.7
—
—
—
0
0
153
1142
1.39
3.40
1.5
1.2
—
—
—
0
0
505
4427
1.25
3.40
3.4
3.2
0.0
0.0
estimate
0.50
84
798
261
2113
1.30
3.38
2.4
2.1
—
—
—
0
0
278
2277
1.29
3.29
3.2
2.8
0.4
0.5
e6/l
0.41
217
1697
865
8069
1.27
3.29
19.2
13.7
13.6
13.5
%
0.21
851
7877
77
508
1.55
3.22
2.1
1.6
1.2
1.3
g/l
0.65
72
464
104
735
1.46
3.14
4.2
2.2
35.2
44.5
u/l
0.65
90
644
288
2385
1.28
3.11
2.0
2.1
157.9
225.3
u/l
1.12
269
2233
260
2130
1.28
3.06
3.0
2.8
1396.6
1107.3
ng/l
0.40
227
1801
506
4480
1.23
2.99
3.5
3.2
0.0
0.0
estimate
0.50
83
777
342
2903
1.25
2.99
5.2
4.4
4.4
2.5
ug/l
0.68
314
2625
41
235
1.77
2.96
1.9
2.3
10.2
11.5
mg/l
0.93
41
218
21
95
2.23
2.91
1.7
1.3
—
—
—
0
0
122
902
1.39
2.89
4.5
2.5
7.7
7.9
umol/l
0.06
106
790
82
565
1.49
2.84
1.2
1.2
—
—
—
0
0
98
700
1.44
2.82
3.9
3.7
0.7
0.9
%
0.27
26
198
16
65
2.48
2.79
1.6
1.4
—
—
—
0
0
5
6
8.36
2.75
1.2
1.0
5.7
4.6
nmol/l
—
5
6
89
628
1.45
2.74
4.0
3.7
0.4
0.4
%
0.06
22
144
7
14
5.02
2.73
6.7
2.5
—
—
—
0
0
13
48
2.73
2.72
3.5
2.5
804.0
882.0
e6/l
—
7
22
29
153
1.92
2.72
1.4
2.4
—
—
—
0
0
28
146
1.94
2.72
1.1
1.0
—
—
—
0
0
177
1401
1.31
2.70
2.7
2.9
2.4
2.4
mmol/l
0.38
158
1249
128
966
1.36
2.69
1.4
1.3
—
—
—
0
0
74
506
1.49
2.67
1.6
1.9
—
—
—
0
0
89
633
1.44
2.64
4.0
3.8
0.0
0.6
%
0.56
23
153
60
394
1.55
2.61
4.1
3.3
—
—
—
0
0
93
672
1.42
2.54
4.0
3.8
0.1
0.1
%
0.07
24
181
268
2254
1.25
2.50
3.2
2.7
—
—
—
0
0
243
2022
1.25
2.49
2.0
1.8
—
—
—
0
0
85
608
1.43
2.46
2.2
2.7
62.4
70.3
e9/l
1.35
61
462
205
1677
1.27
2.43
3.0
2.8
0.7
0.8
ug/l
0.66
136
1028
76
535
1.45
2.40
3.0
3.4
4.4
4.6
pmol/l
0.77
66
470
495
4443
1.20
2.39
4.9
4.5
0.0
0.0
estimate
0.50
86
817
36
213
1.71
2.38
4.3
4.1
—
—
—
0
0
392
3445
1.21
2.37
3.2
3.0
—
5.6
—
0
5
359
3134
1.21
2.32
3.8
3.2
28.6
69.0
ng/l
1.33
237
1999
94
692
1.39
2.32
7.7
3.1
1.6
2.1
mmol/l
0.87
80
541
96
710
1.38
2.31
1.2
1.1
—
—
—
0
0
51
334
1.55
2.28
1.4
1.7
—
—
—
0
0
7
18
3.91
2.25
1.3
1.6
1.1
1.2
mmol/l
—
7
18
49
319
1.56
2.25
1.2
1.2
—
—
—
0
0
303
2609
1.22
2.25
3.3
3.0
7.5
8.0
mmol/l
0.96
253
2224
50
328
1.55
2.22
1.4
1.8
—
—
—
0
0
185
1511
1.27
2.22
1.3
1.2
32.6
28.6
iu/ml
0.14
53
475
84
613
1.40
2.20
12.2
8.4
—
—
—
0
0
27
151
1.81
2.17
7.3
2.6
—
—
—
0
0
25
138
1.83
2.10
1.8
1.8
0.9
0.9
g/l
0.07
18
105
29
168
1.74
2.09
1.5
1.2
—
—
—
0
0
17
82
2.09
2.07
2.5
3.4
—
—
—
0
0
18
89
2.04
2.06
1.6
1.6
—
—
—
0
0
44
287
1.55
2.03
1.7
1.4
11.4
9.1
u/l
0.40
38
236
12
51
2.37
1.95
1.0
1.1
—
—
—
0
0
35
219
1.62
1.92
1.4
1.2
2.7
2.5
u/ml
—
6
18
69
500
1.40
1.91
3.4
3.3
7.4
7.4
ph
—
9
69
946
9082
1.22
1.90
16.8
12.0
40.1
40.3
%
0.18
682
6931
7
22
3.19
1.88
1.4
2.1
—
—
—
0
0
76
562
1.38
1.87
1.4
1.4
—
—
—
0
0
11
46
2.40
1.85
3.9
2.9
966.7
719.4
u/ml
0.25
11
46
6
17
3.54
1.84
1.0
1.1
—
—
—
0
0
6
17
3.54
1.84
1.0
1.0
—
—
—
0
0
6
17
3.54
1.84
1.8
1.6
—
—
—
0
0
5
12
4.18
1.82
1.2
1.3
—
—
—
0
0
195
1640
1.23
1.82
2.9
2.4
561.0
550.3
mosm/kgh2o
0.25
160
1389
18
94
1.93
1.80
1.4
1.7
47.2
59.9
%
—
10
65
7
23
3.06
1.80
1.4
1.1
—
—
—
0
0
21
116
1.83
1.79
1.2
1.4
—
—
—
0
0
57
407
1.42
1.73
1.4
1.8
—
—
—
0
0
52
366
1.44
1.71
3.4
3.3
—
—
—
0
0
197
1670
1.22
1.70
1.8
1.6
—
—
—
0
0
38
251
1.53
1.70
1.2
1.1
—
—
—
0
0
61
446
1.39
1.64
1.4
1.8
—
—
—
0
0
61
446
1.39
1.64
1.4
1.8
—
—
—
0
0
11
49
2.26
1.64
1.0
1.0
—
—
—
0
0
35
230
1.54
1.61
2.0
2.4
88.0
68.7
mg/l
0.19
26
183
35
230
1.54
1.61
2.0
2.4
37.4
53.9
mg/l
0.28
27
183
23
136
1.71
1.59
4.0
2.7
—
—
—
0
0
14
70
2.01
1.59
1.0
1.1
—
—
—
0
0
168
1412
1.22
1.59
1.3
1.2
4.2
8.1
u/ml
0.88
63
612
29
183
1.60
1.58
1.3
1.7
1889.6
13319.7
e6/l
5.03
20
136
6
20
3.01
1.58
1.5
1.7
—
—
—
0
0
17
92
1.86
1.56
1.3
1.1
—
—
—
0
0
86
669
1.31
1.56
1.3
1.2
125.7
154.0
iu/ml
0.36
38
256
60
443
1.37
1.53
1.4
1.8
—
—
—
0
0
664
6247
1.15
1.52
3.7
3.4
—
—
—
0
0
67
508
1.34
1.46
12.1
5.1
—
—
—
0
0
281
2495
1.17
1.44
4.4
3.9
19.3
8.4
mg/mmol
0.74
168
1618
6
22
2.74
1.43
2.0
2.3
—
—
—
0
0
202
1747
1.19
1.43
1.7
1.6
434.6
48815589.8
pmol/l
2.64
163
1477
58
433
1.36
1.40
1.4
1.8
—
—
—
0
0
109
889
1.25
1.38
29.7
19.8
1.5
1.3
inr
—
8
139
202
1754
1.18
1.37
2.6
2.3
3.9
6.5
e6/l
3.01
176
1548
17
285
0.59
1.36
1.3
1.5
—
—
—
0
0
30
199
1.52
1.36
1.3
1.2
—
—
—
0
0
287
2565
1.16
1.35
3.3
2.9
—
—
—
0
0
10
195
0.51
1.33
1.0
1.1
—
—
—
0
0
56
737
0.75
1.33
1.4
1.4
—
—
—
0
0
12
61
1.98
1.33
1.7
1.4
—
—
—
0
0
33
225
1.48
1.32
2.4
3.2
—
—
—
0
0
10
194
0.51
1.32
1.0
1.1
—
—
—
0
0
6
24
2.51
1.30
1.0
1.0
—
—
—
0
0
17
280
0.60
1.28
1.2
1.5
—
—
—
0
0
10
48
2.09
1.28
2.2
3.5
—
—
—
0
0
108
889
1.24
1.27
11.7
7.8
0.8
1.2
mmol/l
0.76
87
692
38
269
1.43
1.27
2.0
2.3
109.8
465.0
ug/l
1.43
32
253
9
44
2.05
1.27
1.7
1.2
128.1
137.3
nmol/l
—
9
44
14
77
1.83
1.25
1.3
1.4
54.7
36.0
%
—
7
50
14
77
1.83
1.25
1.1
1.1
249.3
286.2
mg/l
1.69
14
68
17
277
0.61
1.23
1.2
1.5
—
—
—
0
0
265
2375
1.15
1.20
3.5
3.2
666.1
216.3
mg/l
0.53
152
1540
15
86
1.75
1.19
1.2
1.3
2.9
3.1
g/l
—
10
56
31
214
1.46
1.19
1.1
1.9
38.2
38.2
g/l
0.01
25
188
10
50
2.01
1.16
2.6
4.4
125.1
122.5
nmol/l
—
10
50
14
235
0.59
1.15
1.6
1.7
—
—
—
0
0
15
87
1.73
1.15
1.2
1.3
—
—
—
0
0
5
20
2.51
1.15
1.6
1.1
—
—
—
0
0
48
362
1.34
1.13
1.6
1.6
—
—
—
0
0
24
159
1.52
1.12
2.1
2.7
16.4
16.4
%
0.01
13
86
11
58
1.91
1.12
1.5
1.4
0.5
1.0
u/ml
—
5
29
55
424
1.31
1.12
19.2
10.5
—
—
—
0
0
10
51
1.97
1.11
9.2
10.1
0.6
0.6
mmol/l
—
10
46
97
803
1.23
1.11
3.8
4.3
3.2
12.8
ug/l
2.00
74
656
43
320
1.36
1.11
1.1
1.1
—
—
—
0
0
25
168
1.50
1.10
2.3
2.3
—
—
—
0
0
45
338
1.34
1.09
2.2
1.9
21.7
20.8
s
0.65
39
305
5
21
2.39
1.09
1.4
2.4
—
—
—
0
0
14
81
1.74
1.09
3.3
2.4
—
—
—
0
0
81
659
1.25
1.09
3.0
2.9
—
—
—
0
0
346
3753
0.89
1.07
2.9
2.6
—
—
—
0
0
18
113
1.60
1.06
1.8
1.4
—
—
—
0
0
105
882
1.21
1.05
12.0
7.8
5.1
5.2
kpa
0.24
99
840
105
882
1.21
1.05
12.0
7.8
12.4
12.4
kpa
0.02
100
839
71
573
1.25
1.03
2.4
2.7
—
—
—
0
0
38
281
1.36
1.03
2.3
3.0
0.5
0.2
g/l
0.82
14
113
25
171
1.47
1.03
1.8
1.3
—
—
—
0
0
51
395
1.30
1.02
1.0
1.1
—
—
—
0
0
26
180
1.45
1.01
1.2
1.1
352.9
275.0
u/ml
0.32
16
96
95
796
1.21
0.99
12.9
8.2
96.6
95.4
%
1.53
89
766
15
92
1.64
0.97
1.2
1.2
—
—
—
0
0
40
302
1.34
0.96
4.1
3.4
149.5
4093.3
u/ml
0.66
33
265
43
329
1.32
0.95
1.3
1.2
—
—
—
0
0
19
125
1.53
0.94
1.2
1.1
1.6
1.5
g/l
0.28
19
113
22
151
1.47
0.91
1.1
1.1
—
—
—
0
0
6
29
2.07
0.89
2.7
2.6
—
—
—
0
0
25
177
1.42
0.89
1.8
2.4
133.3
130.7
g/l
0.21
18
139
6
30
2.01
0.87
1.0
1.0
—
—
—
0
0
79
661
1.21
0.86
3.6
3.3
1.2
1.2
mmol/l
0.21
72
583
13
80
1.63
0.84
1.2
1.1
—
—
—
0
0
215
1949
1.13
0.84
3.3
3.5
1.0
1.0
kg/l
0.33
39
308
40
310
1.30
0.83
2.3
2.0
1.3
1.4
ug/l
0.06
35
280
37
285
1.31
0.81
2.4
2.4
—
—
—
0
0
10
58
1.73
0.79
1.1
1.1
—
—
—
0
0
9
147
0.61
0.79
1.0
1.2
—
—
—
0
0
8
48
1.67
0.79
3.6
7.0
—
—
—
0
0
88
753
1.18
0.77
2.0
2.3
13.0
12.9
nmol/l
0.03
79
675
23
168
1.38
0.72
1.2
1.5
0.2
0.4
nmol/l
1.69
17
132
5
26
1.93
0.70
3.0
2.5
—
—
—
0
0
5
26
1.93
0.70
3.4
17.4
—
—
—
0
0
14
93
1.51
0.69
1.0
1.3
—
—
—
0
0
12
77
1.56
0.68
2.2
3.1
—
—
—
0
0
166
1503
1.12
0.68
3.6
3.3
363.5
643.7
ng/l
0.65
128
1105
22
162
1.36
0.66
2.0
1.8
—
—
—
0
0
7
44
1.59
0.65
1.3
1.2
—
—
—
0
0
15
103
1.46
0.65
1.7
2.2
—
—
—
0
0
19
137
1.39
0.65
1.0
1.2
—
—
—
0
0
24
181
1.33
0.63
1.0
1.1
2.2
6.0
u/ml
2.17
14
101
21
155
1.36
0.63
1.4
1.4
—
—
—
0
0
42
342
1.24
0.63
5.1
2.3
0.6
0.7
%
0.51
42
332
227
2102
1.10
0.62
4.4
4.1
—
—
—
0
0
13
88
1.48
0.60
1.0
1.2
—
—
—
0
0
8
51
1.57
0.60
2.8
1.5
11.2
11.3
%
—
8
51
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
24
310
0.77
0.59
4.9
4.3
—
—
—
0
0
27
210
1.29
0.59
1.5
1.3
—
—
—
0
0
51
429
1.20
0.57
1.7
1.4
27.1
25.2
iu/l
0.14
45
370
13
90
1.45
0.55
1.5
2.0
90.7
89.7
%
0.26
13
90
15
107
1.41
0.55
1.7
2.2
107.5
105.8
mmol/l
0.60
15
107
15
107
1.41
0.55
1.7
2.2
4.0
4.0
mmol/l
0.03
15
107
9
60
1.50
0.54
2.4
1.2
—
—
—
0
0
210
1957
1.09
0.51
3.3
3.2
—
—
—
0
0
6
40
1.50
0.51
1.0
1.1
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
11
75
1.47
0.50
1.6
1.4
7399.4
1963.2
e6/l
—
5
54
9
65
1.39
0.50
1.4
1.3
—
—
—
0
0
13
92
1.42
0.50
1.2
2.7
33.4
32.3
pg
0.59
13
92
6
41
1.47
0.50
1.0
1.2
194.8
218.1
iu/ml
—
6
41
14
101
1.39
0.49
5.9
2.7
—
—
—
0
0
108
1191
0.90
0.48
1.3
1.3
—
—
—
0
0
10
68
1.47
0.47
1.0
1.1
—
—
—
0
0
7
48
1.46
0.47
1.0
1.4
—
—
—
0
0
42
356
1.19
0.46
4.7
3.0
26.3
25.0
mmol/l
1.39
42
351
50
431
1.17
0.46
2.2
2.2
4147.0
3659.5
u/l
0.09
20
186
101
1113
0.90
0.45
1.7
1.7
—
—
—
0
0
22
174
1.27
0.45
5.6
3.0
35.9
36.2
umol/l
0.02
17
149
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
25
204
1.23
0.41
1.0
1.1
0.1
2.5
u/ml
—
9
86
12
88
1.37
0.40
1.2
1.1
—
—
nmol/l
—
0
0
10
71
1.41
0.39
1.6
1.8
—
1.8
—
0
6
10
71
1.41
0.39
1.6
1.5
—
—
—
0
0
22
178
1.24
0.39
1.0
1.1
0.2
0.7
u/ml
—
9
78
5
36
1.39
0.38
2.2
1.8
—
—
—
0
0
13
98
1.33
0.37
2.1
2.4
—
—
—
0
0
5
37
1.35
0.37
2.4
1.9
156.4
153.0
nmol/l
—
5
30
22
180
1.23
0.36
2.7
4.4
2.6
2.5
mmol/l
0.01
14
102
15
117
1.29
0.35
1.5
1.1
—
—
—
0
0
6
44
1.37
0.34
1.8
1.8
—
—
—
0
0
22
265
0.83
0.34
1.1
1.1
—
—
—
0
0
6
86
0.70
0.33
1.8
1.5
—
—
—
0
0
6
86
0.70
0.33
1.8
1.5
—
—
—
0
0
6
86
0.70
0.33
1.8
1.5
—
—
—
0
0
6
86
0.70
0.33
1.8
1.5
—
—
—
0
0
120
1119
1.08
0.32
1.3
1.4
—
—
—
0
0
26
222
1.18
0.29
1.2
1.4
515.4
574.7
mg/l
0.30
26
205
861
8500
1.05
0.29
19.5
14.2
332.6
333.3
g/l
1.45
855
8441
274
2844
0.95
0.28
1.5
1.5
—
—
—
0
0
11
85
1.30
0.28
1.5
1.7
—
—
—
0
0
18
149
1.21
0.28
1.3
1.3
—
—
—
0
0
8
63
1.27
0.27
1.6
1.9
—
—
—
0
0
21
177
1.19
0.27
2.6
3.8
321.5
523.6
u/ml
0.17
21
168
247
2377
1.05
0.26
3.7
3.4
0.0
0.0
estimate
1.08
83
786
64
588
1.09
0.26
1.9
1.6
—
—
—
0
0
15
123
1.22
0.25
1.3
1.7
—
—
—
0
0
20
233
0.86
0.24
1.7
2.0
3.0
5.5
iu/l
—
8
78
21
180
1.17
0.24
1.2
1.6
—
—
—
0
0
13
106
1.23
0.23
1.8
2.7
—
—
—
0
0
61
565
1.08
0.22
1.5
1.3
184.0
192.1
u/ml
0.03
56
529
0
10
0.00
0.21
0.0
1.0
—
10.8
—
0
5
0
10
0.00
0.21
0.0
1.4
—
57.1
—
0
10
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
1.7
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
5.4
—
1.2
—
0
14
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
32
288
1.11
0.20
1.4
2.3
—
—
—
0
0
6
50
1.20
0.19
1.2
1.0
383.8
281.5
ng/l
—
6
30
17
146
1.17
0.19
1.2
1.1
99.8
195.3
iu/ml
—
6
37
6
53
1.13
0.18
1.0
1.1
—
—
—
0
0
28
253
1.11
0.17
1.3
1.1
—
—
—
0
0
20
177
1.13
0.16
3.3
3.5
3.6
4.1
e9/l
1.05
20
177
100
956
1.05
0.16
1.6
1.4
—
—
—
0
0
13
151
0.86
0.15
1.0
1.0
3.1
4.6
u/ml
—
6
51
9
80
1.13
0.15
1.1
1.8
—
—
—
0
0
20
223
0.90
0.14
1.4
1.3
—
—
—
0
0
11
93
1.18
0.14
1.2
1.4
11.4
12.1
mmol/l
—
5
19
22
199
1.11
0.13
4.0
3.4
23.2
25.4
mg/l
0.12
14
129
81
775
1.05
0.13
3.8
3.3
—
—
—
0
0
11
94
1.17
0.13
1.4
1.2
—
—
—
0
0
11
94
1.17
0.13
1.1
1.1
—
—
—
0
0
15
169
0.89
0.12
1.2
1.2
—
—
—
0
0
24
220
1.09
0.12
2.1
2.5
590.9
99.9
ug/min
—
9
140
16
143
1.12
0.11
1.4
1.2
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.2
1.0
1536.4
1884.1
miu/ml
—
5
46
5
46
1.09
0.09
1.4
1.5
—
—
—
0
0
6
57
1.05
0.08
1.2
1.2
—
—
—
0
0
5
62
0.81
0.08
2.0
2.3
483.0
488.1
min
—
5
43
7
67
1.05
0.08
2.1
1.5
1.0
1.0
g/l
—
7
67
7
68
1.03
0.08
1.1
1.1
—
—
—
0
0
20
186
1.08
0.07
3.7
3.7
54.3
57.6
%
0.59
20
186
29
306
0.95
0.07
13.0
9.3
—
—
—
0
0
9
104
0.86
0.06
2.0
2.3
—
—
—
0
0
117
1186
0.99
0.03
1.8
1.6
—
—
—
0
0
16
151
1.06
0.03
1.1
1.3
2.5
4.5
u/ml
—
6
70
16
151
1.06
0.03
3.8
2.7
—
—
—
0
0
13
123
1.06
0.01
3.8
2.5
3.9
145.6
u/ml
0.70
13
110
35
343
1.02
0.01
1.3
1.3
305.8
231.4
miu/ml
0.43
17
175
15
144
1.04
0.00
2.5
3.6
14.5
25.6
u/ml
1.35
15
139
13
134
0.97
0.00
1.0
1.0
2.1
6.0
u/ml
—
5
55
14
136
1.03
0.00
1.6
1.7
—
4.6
—
0
5
17
174
0.98
0.00
4.2
4.0
—
—
—
0
0
13
128
1.02
0.00
1.6
1.6
—
—
—
0
0
13
128
1.02
0.00
1.5
1.4
40.9
59.2
mmol/l
—
8
100
17
169
1.01
0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
34.5
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
18
180
1.00
0.00
1.0
1.0
0.2
3.9
u/ml
—
5
44
0
6
0.00
0.00
0.0
5.8
—
—
—
0
0
5
55
0.91
0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
9
94
0.96
0.00
1.3
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.0
1.1
—
7.2
—
0
16
0
5
0.00
0.00
0.0
1.0
—
15.1
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
7
78
0.90
0.00
1.1
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
3.7
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_RESORPTION and mortality.

Females

Parameter HR [95% CI] p-value
K11_RESORPTION 1.033 [0.75, 1.43] 0.847
Birth year 0.994 [0.99, 1.0] 0.146

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 2965 females with K11_RESORPTION died.

Males

Parameter HR [95% CI] p-value
K11_RESORPTION 0.871 [0.65, 1.17] 0.356
Birth year 0.989 [0.98, 1.0] 0.019

During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 2882 males with K11_RESORPTION died.

Mortality risk

Mortality risk for people of age

years, who have K11_RESORPTION.

N-year risk Females Males
1 0.108% 0.166%
5 0.522% 1.078%
10 1.429% 2.797%
15 2.818% 5.232%
20 4.904% 9.057%

Relationships between endpoints

Index endpoint: K11_RESORPTION – Pathological resorption of teeth

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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