This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Lack of expected normal physiological development
R18_LACK_EXPEC_NORMAL_PHYSIO_DEVELOPMENT
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1091 |
4. Check minimum number of eventsNone |
1091 |
5. Include endpoints |
1091 |
6. Filter based on genotype QC (FinnGen only) |
1091 |
Control definitions (FinnGen only)
- Control exclude
- R18_GENERAL_SYMPTOMS_SIGNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- R[5-6]
- Name in latin
- Absentia progressus physiologici normalis exspectati
Similar endpoints
↥List of similar endpoints to
Lack of expected normal physiological development
based on the number of shared cases.
Similar with more cases:
- General symptoms and signs
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1091 | 564 | 527 |
| Unadjusted period prevalence (%) | 0.21 | 0.19 | 0.23 |
| Median age at first event (years) | 3.50 | 3.86 | 3.12 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 726
- Matched controls
- 6962
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
+∞
323.0
326
*
R62.0
ICD-10 Finland
Delayed milestone
933.0
323.0
395
9
R56.8
ICD-10 Finland
Other and unspecified convulsions
845.5
80.8
79
*
F83
ICD-10 Finland
Mixed specific developmental disorders
18.5
69.7
111
67
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
9.7
53.9
116
134
Z3226
NOMESCO Finland
Physiotherapist
4.6
51.2
211
573
XA800
NOMESCO Finland
Neuropsychological investigation
10.9
47.5
95
95
R50.9
ICD-10 Finland
Fever, unspecified
6.6
47.0
131
224
F80.1
ICD-10 Finland
Expressive language disorder
17.0
45.5
74
46
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.1
44.9
134
250
F82
ICD-10 Finland
Specific developmental disorder of motor function
15.3
43.7
74
51
Z2446
NOMESCO Finland
Social worker
5.0
43.1
155
359
R4110
NOMESCO Finland
Physiotherapy
4.0
42.2
196
583
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.4
41.6
172
458
Z2445
NOMESCO Finland
Psychologist
5.0
40.3
144
329
ZXE10
NOMESCO Finland
More than one and less than three hours
3.4
40.2
241
880
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
12.5
37.4
69
58
Z3231
NOMESCO Finland
Registered nurse
3.1
37.2
272
1134
Z2221
NOMESCO Finland
Medical doctor
3.3
37.2
229
844
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
17.5
36.9
59
35
ZXD10
NOMESCO Finland
Scheduled procedure
3.0
36.5
271
1140
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
9.0
35.1
77
90
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.6
34.2
180
582
RL140
NOMESCO Finland
NA
39.7
34.0
43
11
RT150
NOMESCO Finland
NA
27.6
33.4
46
17
R62.9
ICD-10 Finland
Lack of expected normal physiological development, unspecified
+∞
33.0
32
*
ZXE20
NOMESCO Finland
More than three and less than five hours
5.3
32.4
106
217
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
26.3
31.5
44
17
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
27.3
31.1
43
16
Z3229
NOMESCO Finland
Other healthcare associate professional
5.3
30.9
101
206
H01AC01
ATC
somatropin; parenteral
12.0
30.0
56
48
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.1
29.9
86
150
XF400
NOMESCO Finland
ECG with 12 standard connections
3.9
28.8
133
382
602
Kela drug reimbursment
Children's severe malnutrition
11.6
28.0
53
47
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.4
27.9
152
498
N03AG01
ATC
valproic acid; systemic, rectal
7.8
27.7
66
88
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.0
27.1
93
200
G40.9
ICD-10 Finland
Epilepsy, unspecified
18.8
26.6
41
22
Z31.5
ICD-10 Finland
Genetic counselling
5.2
26.4
86
174
R1260
NOMESCO Finland
Evaluation of communicative skills
24.8
26.2
37
15
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
24.9
130
410
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.1
24.8
83
173
TPH04
NOMESCO Finland
Cathetrisation of vein
3.6
24.7
122
368
N03AF02
ATC
oxcarbazepine; oral
15.3
24.7
41
27
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
23.4
24.4
35
15
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
15.5
24.2
40
26
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
11.1
24.0
46
42
F80.2
ICD-10 Finland
Receptive language disorder
10.2
23.9
48
48
R4120
NOMESCO Finland
Occupational therapy
6.9
23.8
61
91
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.2
23.8
59
84
TPH07
NOMESCO Finland
Cathetrisation of artery
6.1
23.7
67
114
ZXE00
NOMESCO Finland
One hour or less
2.4
23.7
286
1504
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
23.5
203
890
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.5
22.6
116
360
E34.35
ICD-10 Finland
Abnormal growth retardation
8.3
22.5
51
63
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
22.1
173
714
N03AX14
ATC
levetiracetam; systemic
15.0
21.6
36
24
R51.80
ICD-10 Finland
Headache
3.9
21.6
96
264
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
21.3
135
486
101
Kela drug reimbursment
Anterior pituitary hypofunction
12.7
21.3
38
30
N05BA01
ATC
diazepam; systemic, rectal
5.6
20.9
63
116
N05CD08
ATC
midazolam; nasal, systemic
23.0
20.9
30
13
R55
ICD-10 Finland
Syncope and collapse
11.9
20.6
38
32
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.9
19.7
85
227
R56.0
ICD-10 Finland
Febrile convulsions
+∞
19.6
19
*
Z50.5
ICD-10 Finland
Speech therapy
5.5
19.4
59
110
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
4.5
19.1
71
165
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
7.6
19.0
45
60
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.2
18.7
60
119
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
14.7
18.6
31
21
FM2CE
NOMESCO Finland
NA
5.2
18.4
59
117
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
98.4
18.3
20
*
RT490
NOMESCO Finland
NA
37.9
18.3
23
6
RT160
NOMESCO Finland
NA
14.0
18.2
31
22
ZXD20
NOMESCO Finland
Day surgery
3.4
17.6
92
288
N05AX08
ATC
risperidone; systemic
4.1
17.5
70
175
H50.31
ICD-10 Finland
Intermittent exotropia
7.1
17.4
43
61
N05BA09
ATC
clobazam; oral
19.8
17.4
26
13
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.2
17.3
97
319
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.3
17.3
34
33
H02AB09
ATC
hydrocortisone; systemic
6.6
17.3
45
69
EBA15
NOMESCO Finland
Extraction of large number of teeth
9.7
17.3
35
36
WX882
NOMESCO Finland
High dependency care
4.8
17.2
59
126
H50.30
ICD-10 Finland
Intermittent esotropy
11.4
17.2
32
28
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
13.1
16.6
29
22
P85
ICPC
Mental retardation
25.2
16.6
23
9
RD210
NOMESCO Finland
NA
4.6
16.5
59
132
WX892
NOMESCO Finland
Monitored bed care
4.9
16.2
54
112
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
16.1
173
831
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.3
15.9
85
270
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.5
15.9
57
128
ZX114
NOMESCO Finland
Intramuscular
18.2
15.7
24
13
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.0
15.6
96
334
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.1
15.4
61
151
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
5.3
15.2
47
90
ZXA10
NOMESCO Finland
Bilateral
2.6
15.0
118
481
183
Kela drug reimbursment
Lamotrigin and topiramate
15.8
14.9
24
15
RS222
NOMESCO Finland
NA
10.7
14.7
28
26
RL130
NOMESCO Finland
NA
12.2
14.6
26
21
R68.1
ICD-10 Finland
Nonspecific symptoms peculiar to infancy
55.5
14.5
17
*
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
5.5
14.4
43
79
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
7.1
14.4
35
49
M41.4
ICD-10 Finland
Neuromuscular scoliosis
+∞
14.4
14
*
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
78.3
14.3
16
*
R4130
NOMESCO Finland
Speech therapy
9.9
14.1
28
28
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
26.6
14.0
19
7
N03AX09
ATC
lamotrigine; oral
4.3
14.0
53
126
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
21.8
13.9
20
9
XF600
NOMESCO Finland
Bloodpressure measurement
3.3
13.9
72
223
C03DA01
ATC
spironolactone; oral
6.7
13.9
35
52
ZXD05
NOMESCO Finland
Urgent procedure
2.1
13.8
173
883
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
13.4
135
625
G40.89
ICD-10 Finland
Other epilepsy
+∞
13.4
13
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.5
13.2
64
189
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
25.2
13.1
18
7
A11CC03
ATC
alfacalcidol; systemic
12.6
13.1
23
18
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
17.9
13.1
20
11
A28
ICPC
Limited function/disability NOS
4.9
13.0
43
89
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
10.3
12.9
25
24
ZY010
NOMESCO Finland
Hospital outpatient
2.7
12.9
90
341
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
4.1
12.9
50
122
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.0
12.7
181
972
H50.0
ICD-10 Finland
Convergent concomitant strabismus
6.6
12.6
32
48
ZX120
NOMESCO Finland
Intravenous
3.8
12.5
54
145
C03CA01
ATC
furosemide; systemic
5.4
12.5
37
68
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.9
12.5
79
280
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
12.5
72
242
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.7
12.3
31
46
ZXA00
NOMESCO Finland
Right side
2.6
12.3
92
362
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.7
12.3
28
36
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
12.3
136
657
RT190
NOMESCO Finland
NA
23.8
12.2
17
7
201
Kela drug reimbursment
Chronic cardiac insufficiency
8.6
12.2
26
30
127
Kela drug reimbursment
Transplant complication
12.9
12.2
21
16
ZX199
NOMESCO Finland
Other rote
36.6
12.0
15
*
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
6.4
12.0
31
48
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.3
11.9
61
188
TAB00
NOMESCO Finland
Lumbar puncture
5.6
11.9
34
60
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
20.8
11.8
17
8
RS220
NOMESCO Finland
NA
7.4
11.6
27
36
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.9
11.5
37
75
J45.1
ICD-10 Finland
Nonallergic asthma
2.7
11.5
79
297
205
Kela drug reimbursment
Chronic hypertension
6.2
11.4
30
48
XX4AW
NOMESCO Finland
NA
10.9
11.3
21
19
XF404
NOMESCO Finland
Ambulatory ECG
3.7
11.3
49
133
RT274
NOMESCO Finland
NA
116.7
11.3
12
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
8.4
11.2
24
28
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
34.1
11.1
14
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.5
11.0
32
58
E34.30
ICD-10 Finland
Short stature NOS
8.7
11.0
23
26
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
9.4
11.0
22
23
V03AG01
ATC
sodium cellulose phosphate; systemic
16.6
11.0
17
10
TJD20
NOMESCO Finland
Change of gastrostomy tube
24.4
10.9
15
6
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.5
10.9
85
344
N05AH04
ATC
quetiapine; oral
2.2
10.8
126
617
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
7.9
10.8
24
30
R5140
NOMESCO Finland
Monitoring the use of the aid
6.3
10.8
28
44
B01AA03
ATC
warfarin; systemic
6.0
10.7
29
48
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
42.2
10.7
13
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
10.7
449
3391
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.5
10.6
50
145
E34.31
ICD-10 Finland
Short stature, prenatal disorder
11.6
10.6
19
16
JDB10
NOMESCO Finland
Percutaneous gastrostomy
27.3
10.5
14
5
SPAT1229
SPAT
Assessment of need for aid
6.4
10.5
27
42
P94.2
ICD-10 Finland
Congenital hypotonia
58.3
10.4
12
*
Q99.8
ICD-10 Finland
Other specified chromosome abnormalities
58.3
10.4
12
*
H66.9
ICD-10 Finland
Otitis media, unspecified
2.0
10.3
145
769
XF602
NOMESCO Finland
Bloodpressure monitoring
11.0
10.3
19
17
H03AA01
ATC
levothyroxine sodium; systemic
2.5
10.3
81
329
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.3
10.3
52
160
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
13.9
10.2
17
12
K03.66
ICD-10 Finland
Tooth plaque
2.2
10.2
105
489
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.3
10.1
51
157
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
10.3
10.0
19
18
C08CA01
ATC
amlodipine; oral
4.1
10.0
38
92
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
9.9
94
420
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.0
9.9
58
198
UDC00
NOMESCO Finland
Ear microscopy
2.6
9.8
72
281
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
14.2
9.8
16
11
P07.3
ICD-10 Finland
Other preterm infants
3.6
9.7
43
119
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
16.3
9.7
15
9
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.9
9.6
39
100
XF622
NOMESCO Finland
Measurement of minute volume of heart
25.3
9.6
13
5
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
4.7
9.6
32
68
C09AA02
ATC
enalapril; systemic
4.7
9.6
32
68
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
7.9
9.6
21
26
R1250
NOMESCO Finland
Evaluation of functional capability
7.9
9.6
21
26
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
7.9
9.6
21
26
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.7
9.5
41
111
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
9.5
146
799
A03FA02
ATC
cisapride; oral, rectal
4.0
9.5
37
92
E23.00
ICD-10 Finland
Panhypopituitarism
53.4
9.5
11
*
F79.1
ICD-10 Finland
Unspecified mental retardation, significant impairment of behaviour requiring attention or treatment
53.4
9.5
11
*
N03AX16
ATC
pregabalin; oral
3.3
9.3
46
139
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
14.6
9.3
15
10
R63.4
ICD-10 Finland
Abnormal weight loss
8.9
9.3
19
21
XKD00
NOMESCO Finland
Uroflowmetry
3.5
9.3
42
119
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
9.2
9
*
5AB14
NOMESCO Finland
NA
+∞
9.2
9
*
RT130
NOMESCO Finland
NA
17.1
9.2
14
8
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.8
9.1
20
25
C01AA05
ATC
digoxin; systemic
13.3
9.0
15
11
Z94.0
ICD-10 Finland
Kidney transplant status
13.3
9.0
15
11
H52.0
ICD-10 Finland
Hypermetropia
3.7
9.0
38
102
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
8.9
238
1555
N03AX11
ATC
topiramate; oral
6.5
8.9
22
33
KAC00
NOMESCO Finland
Nephrectomy
35.6
8.9
11
*
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
35.6
8.9
11
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
35.6
8.9
11
*
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
11.2
8.8
16
14
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
6.1
8.8
23
37
WX002
NOMESCO Finland
Sedation and analgesia
2.4
8.7
74
313
F90.0
ICD-10 Finland
Disturbance of activity and attention
2.4
8.6
76
327
AA1AD
NOMESCO Finland
CT of head and brain
2.9
8.6
50
170
N99
ICPC
Neurological disease other
48.5
8.5
10
*
XF402
NOMESCO Finland
ECG with work load test
4.1
8.4
32
78
A41.9
ICD-10 Finland
Sepsis, unspecified
6.0
8.3
22
36
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.9
8.3
50
174
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
8.7
8.3
17
19
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
87.2
8.3
9
*
N03AG04
ATC
vigabatrin; oral
+∞
8.2
8
*
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
8.2
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
8.2
87
407
XG413
NOMESCO Finland
Spirometry with oscillometry
9.2
8.1
16
17
WX722
NOMESCO Finland
PEEP
6.1
8.1
21
34
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.1
8.0
43
139
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
8.0
48
167
G40.10
ICD-10 Finland
Simple partial seizures
14.1
8.0
13
9
B34.9
ICD-10 Finland
Viral infection, unspecified
2.8
8.0
50
177
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
4.3
7.9
28
64
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
7.9
40
124
J96.1
ICD-10 Finland
Chronic respiratory failure
32.3
7.9
10
*
WX730
NOMESCO Finland
Conventional respirator
16.7
7.9
12
7
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
11.4
7.9
14
12
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
21.4
7.9
11
5
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
3.9
7.8
31
79
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
4.7
7.8
25
52
E30.09
ICD-10 Finland
Delayed puberty NOS
7.0
7.7
18
25
R11
ICD-10 Finland
Nausea and vomiting
2.4
7.7
65
274
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
7.5
7.7
17
22
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
7.6
113
609
K59.0
ICD-10 Finland
Constipation
3.0
7.6
41
134
UGC02
NOMESCO Finland
Rigid bronchoscopy
9.1
7.6
15
16
BC00A
NOMESCO Finland
NA
43.5
7.6
9
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.6
7.5
32
87
H52.2
ICD-10 Finland
Astigmatism
3.6
7.5
32
87
K59.09
ICD-10 Finland
Constipation, unspecified
3.3
7.5
36
108
301
Kela drug reimbursment
Growth hormone
7.2
7.5
17
23
A02BC01
ATC
omeprazole; systemic
2.1
7.4
84
405
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
5.8
7.4
20
34
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
24.2
7.4
10
*
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
24.2
7.4
10
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
7.8
7.4
16
20
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.8
7.3
23
47
ZXA05
NOMESCO Finland
Left side
2.2
7.3
70
315
JDB00
NOMESCO Finland
Gastrostomy
77.4
7.3
8
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
77.4
7.3
8
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.9
7.3
28
70
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.9
7.3
28
70
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
6.9
7.3
17
24
R62
ICD-10 Finland
Lack of expected normal physiological development
+∞
7.2
7
*
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
5.8
7.1
19
32
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.2
7.1
35
107
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
4.1
7.1
26
62
61
HP
Catheterization and pressure measurement of the left side of the heart
15.3
7.1
11
7
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.7
7.1
29
77
Q93.8
ICD-10 Finland
Other deletions from the autosomes
29.0
7.0
9
*
UKC02
NOMESCO Finland
Cystoscopy
3.3
7.0
33
98
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
19.4
7.0
10
5
137
Kela drug reimbursment
Uraemia requiring dialysis
19.4
7.0
10
5
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.8
7.0
28
73
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
11.7
6.9
12
10
RK110
NOMESCO Finland
NA
11.7
6.9
12
10
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.8
6.9
44
159
F80.0
ICD-10 Finland
Specific speech articulation disorder
4.7
6.9
22
46
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
6.9
103
555
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.7
6.9
44
160
31
HP
Congenital heart failure surgery
8.5
6.9
14
16
Q62.7
ICD-10 Finland
Congenital vesico-uretero-renal reflux
9.7
6.8
13
13
DFF20
NOMESCO Finland
Audiometry for children
9.7
6.8
13
13
F98.00
ICD-10 Finland
Nonorganic enuresis nocturna
3.9
6.8
26
65
F98.02
ICD-10 Finland
Non-organic nocturnal and diurnal enuresis
6.1
6.7
17
27
N03AX12
ATC
gabapentin; oral
3.4
6.7
31
91
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
6.7
58
247
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.0
6.7
36
118
DFF00
NOMESCO Finland
Pure tone audiometry
3.2
6.7
33
102
G91.1
ICD-10 Finland
Obstructive hydrocephalus
38.6
6.6
8
*
Q93.5
ICD-10 Finland
Other deletions of part of a chromosome
38.6
6.6
8
*
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
10.6
6.6
12
11
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
10.6
6.6
12
11
RS224
NOMESCO Finland
NA
6.5
6.6
16
24
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
16.2
6.6
10
6
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
16.2
6.6
10
6
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.6
6.6
28
77
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
4.3
6.6
23
53
B05DA
ATC
Isotonic solutions
21.8
6.5
9
*
G04BE03
ATC
sildenafil; oral
21.8
6.5
9
*
P05.1
ICD-10 Finland
Small for gestational age
7.0
6.5
15
21
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.2
6.5
23
54
N06BA04
ATC
methylphenidate; oral
2.3
6.5
57
247
N05AH03
ATC
olanzapine; systemic
2.5
6.5
48
189
WW500
NOMESCO Finland
Blood transfusion
6.2
6.4
16
25
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
7.6
6.4
14
18
R03BA02
ATC
budesonide; inhalant
1.8
6.4
110
624
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
5.7
6.4
17
29
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.0
6.4
34
111
XW000
NOMESCO Finland
Bone marrow biopsy
5.3
6.4
18
33
R04.0
ICD-10 Finland
Epistaxis
3.2
6.4
31
95
A12AA04
ATC
calcium carbonate; oral
9.7
6.4
12
12
KA1AE
NOMESCO Finland
Kidney ultrasound examination
6.6
6.3
15
22
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
67.5
6.3
7
*
N03AX15
ATC
zonisamide; oral
13.8
6.2
10
7
XG410
NOMESCO Finland
Flow-volume spirometry
3.0
6.2
34
113
N05AN01
ATC
lithium; oral
5.5
6.2
17
30
H02AB04
ATC
methylprednisolone; systemic
2.8
6.2
38
136
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
6.2
6
*
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
+∞
6.2
6
*
4AA09
NOMESCO Finland
NA
+∞
6.2
6
*
R51
NOMESCO Finland
Aids services
+∞
6.2
6
*
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
6.2
6
*
N06AX11
ATC
mirtazapine; oral
1.8
6.1
109
622
BF20A
NOMESCO Finland
NA
17.4
6.1
9
5
H47.2
ICD-10 Finland
Optic atrophy
17.4
6.1
9
5
Q21.10
ICD-10 Finland
Persistent ostium secundum
3.8
6.1
24
62
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
9.0
6.1
12
13
R5599
NOMESCO Finland
Other rehabilitation service
3.5
6.1
26
72
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
25.8
6.1
8
*
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
25.8
6.1
8
*
L28
ICPC
Limited function/disability (L)
2.5
6.1
44
173
C07AB07
ATC
bisoprolol; oral
2.2
6.1
60
275
H50.1
ICD-10 Finland
Divergent concomitant strabismus
5.8
6.1
16
27
IGY99
NOMESCO Finland
Other psychiatric treatment contact
2.5
6.1
44
174
ZYC01
NOMESCO Finland
Remote contact by phone
2.5
6.1
46
185
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_LACK_EXPEC_NORMAL_PHYSIO_DEVELOPMENT – Lack of expected normal physiological development
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).