No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- KRA_PSY_ANYMENTAL
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F80-F89
- Name in latin
- Perturbatio specifica progressus functionis motoricae
Similar endpoints
↥List of similar endpoints to
Motor disorders, excluding more controls
based on the number of shared cases.
Similar with more cases:
- Specific developmental disorder of motor function
- Motor disorders
- Disorders of psychological development
- Any mental disorder
- Psychiatric diseases
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19285 | 5193 | 14091 |
| Only index persons | 14350 | 3746 | 10604 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.33 | 0.15 | 0.39 |
| Only index persons | 0.34 | 0.14 | 0.40 |
| Median age at first event (years) | |||
| Whole population | 5.64 | 5.23 | 5.79 |
| Only index persons | 6.01 | 5.73 | 6.11 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 612 | 255 | 357 |
| Unadjusted period prevalence (%) | 0.13 | 0.09 | 0.16 |
| Median age at first event (years) | 6.12 | 6.05 | 6.17 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 539
- Matched controls
- 5187
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F82
ICD-10 Finland
Specific developmental disorder of motor function
9844.3
323.0
504
5
F83
ICD-10 Finland
Mixed specific developmental disorders
1812.6
149.4
140
*
F80.1
ICD-10 Finland
Expressive language disorder
309.1
104.3
104
*
XA800
NOMESCO Finland
Neuropsychological investigation
28.7
103.2
144
65
R62.0
ICD-10 Finland
Delayed milestone
36.8
97.6
127
43
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
13.3
91.6
174
179
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
16.5
81.4
138
106
F90.0
ICD-10 Finland
Disturbance of activity and attention
20.6
80.2
124
74
N05AH04
ATC
quetiapine; oral
21.8
75.4
114
63
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
33.6
73.9
98
34
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
72.6
69
*
F80.2
ICD-10 Finland
Receptive language disorder
270.1
72.2
73
*
R4120
NOMESCO Finland
Occupational therapy
18.4
69.7
112
73
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
9.4
69.0
158
220
N05AX08
ATC
risperidone; systemic
248.9
66.9
68
*
N05AH03
ATC
olanzapine; systemic
364.7
66.1
66
*
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
128.7
65.6
70
6
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
224.1
60.5
62
*
N05AX12
ATC
aripiprazole; systemic
597.5
56.9
56
*
R4110
NOMESCO Finland
Physiotherapy
5.3
55.7
211
565
F29
ICD-10 Finland
Unspecified nonorganic psychosis
561.8
53.7
53
*
N06BA04
ATC
methylphenidate; oral
19.7
52.3
81
46
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
+∞
51.2
49
*
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
20.8
49.4
75
40
F32.9
ICD-10 Finland
Depressive episode, unspecified
11.5
46.0
90
89
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
129.3
45.9
49
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.9
43.5
167
435
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
11.0
42.6
85
87
RT150
NOMESCO Finland
NA
94.3
40.8
45
5
F93.89
ICD-10 Finland
Other childhood emotional disorders
213.0
39.8
41
*
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
109.3
38.7
42
*
IGY99
NOMESCO Finland
Other psychiatric treatment contact
35.2
38.5
50
15
3154A
ICD-9 Finland
Specific delays in development, Coördination disorder
+∞
38.5
37
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
17.3
37.9
61
38
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.0
37.3
184
597
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
72.7
36.9
42
6
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.9
36.9
99
164
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
190.7
35.7
37
*
N03AX09
ATC
lamotrigine; oral
49.8
35.6
43
9
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
14.6
34.9
60
44
RL140
NOMESCO Finland
NA
67.2
33.9
39
6
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
345.3
33.8
34
*
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
26.7
33.1
46
18
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
334.3
32.8
33
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.1
32.2
148
443
R1260
NOMESCO Finland
Evaluation of communicative skills
63.5
31.9
37
6
Z50.5
ICD-10 Finland
Speech therapy
8.1
31.7
75
102
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
89.9
31.6
35
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
6.8
31.4
84
137
F81.0
ICD-10 Finland
Specific reading disorder
71.7
30.7
35
5
N06AB03
ATC
fluoxetine; oral
16.1
29.8
49
32
N03AG01
ATC
valproic acid; systemic, rectal
11.7
29.5
56
51
R5599
NOMESCO Finland
Other rehabilitation service
31.0
29.3
39
13
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
81.8
28.6
32
*
RT160
NOMESCO Finland
NA
28.0
27.8
38
14
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
6.1
27.5
79
141
Z01.8
ICD-10 Finland
Other specified special examinations
4.0
27.4
126
371
602
Kela drug reimbursment
Children's severe malnutrition
9.1
27.3
59
69
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
+∞
26.9
26
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
+∞
26.9
26
*
N05AH02
ATC
clozapine; systemic
+∞
26.9
26
*
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
63.1
26.8
31
5
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
46.6
26.3
32
7
RL130
NOMESCO Finland
NA
46.6
26.3
32
7
R4130
NOMESCO Finland
Speech therapy
14.8
26.0
44
31
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
+∞
25.9
25
*
TPH04
NOMESCO Finland
Cathetrisation of vein
4.1
25.7
112
313
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
73.4
25.6
29
*
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
50.8
25.1
30
6
N06AB10
ATC
escitalopram; oral
4.8
24.9
90
209
F20.9
ICD-10 Finland
Schizophrenia, unspecified
+∞
24.8
24
*
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
58.8
24.8
29
5
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.4
24.7
79
160
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
251.7
24.5
25
*
IGY02
NOMESCO Finland
Psychiatric monitoring contact
10.5
24.2
48
48
IGP01
NOMESCO Finland
Psychiatric family contact
22.4
24.1
35
16
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
56.7
23.8
28
5
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
+∞
23.8
23
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
6.8
23.7
62
97
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
4.7
23.7
87
205
N05AA02
ATC
levomepromazine; systemic
241.2
23.5
24
*
N06AX16
ATC
venlafaxine; oral
9.6
23.1
48
52
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
47.2
23.1
28
6
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.3
22.4
62
105
R1250
NOMESCO Finland
Evaluation of functional capability
27.7
22.0
30
11
G40.9
ICD-10 Finland
Epilepsy, unspecified
11.1
22.0
42
39
P07.2
ICD-10 Finland
Extreme immaturity
52.4
21.9
26
5
RS222
NOMESCO Finland
NA
21.0
21.0
31
15
F84.5
ICD-10 Finland
Asperger syndrome
60.3
20.7
24
*
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
+∞
20.7
20
*
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
77.0
20.5
23
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
15.1
20.5
34
23
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
20.3
184
852
XF400
NOMESCO Finland
ECG with 12 standard connections
3.1
20.3
125
454
T36
ICD-10 Finland
Poisoning by systemic antibiotics
17.5
19.8
31
18
183
Kela drug reimbursment
Lamotrigin and topiramate
57.6
19.7
23
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
19.7
167
741
N03AX14
ATC
levetiracetam; systemic
13.3
19.5
34
26
Z31.5
ICD-10 Finland
Genetic counselling
4.9
19.2
65
140
RF120
NOMESCO Finland
NA
31.4
19.0
25
8
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
19.0
120
439
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
+∞
18.6
18
*
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
+∞
18.6
18
*
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
5.9
18.5
53
94
N06AB06
ATC
sertraline; oral
6.9
18.5
47
71
H52.2
ICD-10 Finland
Astigmatism
7.2
18.2
45
65
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.8
18.2
53
96
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
44.0
18.0
22
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.2
18.0
107
374
ZXA00
NOMESCO Finland
Right side
3.3
17.7
98
328
IGV01
NOMESCO Finland
Psychiatric network contact
66.4
17.5
20
*
N06AX11
ATC
mirtazapine; oral
4.1
17.5
73
193
N05BA04
ATC
oxazepam; oral
5.5
17.4
53
101
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
9.4
17.4
36
39
IEV99
NOMESCO Finland
Other psychiatric network intervention
63.0
16.6
19
*
F88
ICD-10 Finland
Other disorders of psychological development
63.0
16.6
19
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
+∞
16.5
16
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
16.5
95
325
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.9
16.4
72
199
F41.1
ICD-10 Finland
Generalized anxiety disorder
8.1
16.3
37
47
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
168.6
16.3
17
*
A28
ICPC
Limited function/disability NOS
5.4
16.2
50
97
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.4
16.0
49
94
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
15.9
81
254
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
18.5
15.8
24
13
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.3
15.8
35
43
XX4AW
NOMESCO Finland
NA
8.7
15.7
34
40
H01AC01
ATC
somatropin; parenteral
6.2
15.7
43
72
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
+∞
15.5
15
*
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
+∞
15.5
15
*
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
22.0
15.3
22
10
N05CD08
ATC
midazolam; nasal, systemic
7.5
15.2
36
49
N05BA09
ATC
clobazam; oral
14.8
15.1
25
17
IEP99
NOMESCO Finland
Other psychiatric family intervention
44.7
14.9
18
*
RD210
NOMESCO Finland
NA
4.4
14.7
54
127
F99
ICD-10 Finland
Mental disorder, not otherwise specified
56.2
14.6
17
*
K03.66
ICD-10 Finland
Tooth plaque
2.9
14.6
97
364
WX882
NOMESCO Finland
High dependency care
3.4
14.6
76
242
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
18.3
14.5
22
12
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
13.2
14.5
25
19
SPAT1307
SPAT
Psychosocial counselling and guidance
3.2
14.4
82
278
RT490
NOMESCO Finland
NA
79.3
14.4
16
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
148.2
14.3
15
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
35.7
14.3
18
5
ZXA05
NOMESCO Finland
Left side
3.1
13.8
81
278
ZXA10
NOMESCO Finland
Bilateral
2.8
13.8
99
388
R11
ICD-10 Finland
Nausea and vomiting
3.4
13.6
68
210
RS220
NOMESCO Finland
NA
9.1
13.5
28
31
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
74.2
13.4
15
*
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
+∞
13.4
13
*
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
+∞
13.4
13
*
F54
ICD-10 Finland
Psychological and behavioural factors associated with disorders or diseases classified elsewhere
138.0
13.3
14
*
L02AE02
ATC
leuprorelin; implant, parenteral
16.1
13.2
21
13
WX730
NOMESCO Finland
Conventional respirator
18.1
13.2
20
11
RS211
NOMESCO Finland
NA
13.7
13.0
22
16
N05BA06
ATC
lorazepam; systemic, sublingual
39.6
13.0
16
*
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
39.6
13.0
16
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.5
12.9
46
105
FM2CE
NOMESCO Finland
NA
3.5
12.8
62
186
SPAT1234
SPAT
Support of social functional capacity
10.9
12.8
24
22
F98.00
ICD-10 Finland
Nonorganic enuresis nocturna
10.9
12.8
24
22
EBA15
NOMESCO Finland
Extraction of large number of teeth
8.8
12.8
27
31
F39
ICD-10 Finland
Unspecified mood [affective] disorder
18.9
12.7
19
10
H50.0
ICD-10 Finland
Convergent concomitant strabismus
8.1
12.6
28
35
SPAT1229
SPAT
Assessment of need for aid
10.5
12.5
24
23
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
31.7
12.4
16
5
F90.1
ICD-10 Finland
Hyperkinetic conduct disorder
+∞
12.4
12
*
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
+∞
12.4
12
*
P72
ICPC
Schizophrenia
+∞
12.4
12
*
Z63.8
ICD-10 Finland
Other specified problems related to primary support group
+∞
12.4
12
*
RT422
NOMESCO Finland
NA
+∞
12.4
12
*
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
3.9
12.4
52
139
F98.02
ICD-10 Finland
Non-organic nocturnal and diurnal enuresis
127.9
12.3
13
*
H50.31
ICD-10 Finland
Intermittent exotropia
6.7
12.3
31
47
N05BA01
ATC
diazepam; systemic, rectal
4.4
12.2
45
106
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
13.1
12.2
21
16
WX002
NOMESCO Finland
Sedation and analgesia
3.2
12.2
67
219
RF420
NOMESCO Finland
NA
26.4
11.9
16
6
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.3
11.9
61
192
F43.1
ICD-10 Finland
Post-traumatic stress disorder
14.5
11.6
19
13
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.3
11.5
60
191
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
16.2
11.5
18
11
P85
ICPC
Mental retardation
29.6
11.5
15
5
JDB10
NOMESCO Finland
Percutaneous gastrostomy
29.6
11.5
15
5
F50.9
ICD-10 Finland
Eating disorder, unspecified
29.6
11.5
15
5
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.4
11.5
105
472
P74
ICPC
Anxiety disorder/anxiety state
5.4
11.4
34
64
F84.8
ICD-10 Finland
Other pervasive developmental disorders
+∞
11.3
11
*
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
+∞
11.3
11
*
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
+∞
11.3
11
*
F93.1
ICD-10 Finland
Phobic anxiety disorder of childhood
+∞
11.3
11
*
F93.80
ICD-10 Finland
Generalized anxiety in the bardom age
+∞
11.3
11
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
11.3
11
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
8.6
11.3
24
28
RT130
NOMESCO Finland
NA
117.9
11.3
12
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.0
11.2
171
964
WX722
NOMESCO Finland
PEEP
6.1
11.1
30
50
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
24.7
11.0
15
6
C07AA05
ATC
propranolol; systemic
3.0
10.9
66
232
F40.1
ICD-10 Finland
Social phobias
8.0
10.9
24
30
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.4
10.8
32
60
H53.0
ICD-10 Finland
Amblyopia ex anopsia
5.8
10.8
30
52
F40.2
ICD-10 Finland
Specific (isolated) phobias
42.6
10.8
13
*
C03CA01
ATC
furosemide; systemic
5.1
10.7
33
65
SPAT1240
SPAT
Therapeutic discussion
2.7
10.6
75
290
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
10.6
59
195
H35.1
ICD-10 Finland
Retinopathy of prematurity
27.6
10.6
14
5
SPAT1389
SPAT
Visit based on need for special support
2.8
10.5
71
266
TJD20
NOMESCO Finland
Change of gastrostomy tube
21.2
10.5
15
7
N06AB04
ATC
citalopram; systemic
5.8
10.5
29
50
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
58.9
10.5
12
*
RS312
NOMESCO Finland
NA
58.9
10.5
12
*
Z07
ICPC
Education problem
7.5
10.5
24
32
AA1AD
NOMESCO Finland
CT of head and brain
3.5
10.4
49
145
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.5
10.4
30
55
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
+∞
10.3
10
*
F98.9
ICD-10 Finland
Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
+∞
10.3
10
*
RT420
NOMESCO Finland
NA
+∞
10.3
10
*
IEY01
NOMESCO Finland
Psychoeducation, individual
+∞
10.3
10
*
F89
ICD-10 Finland
Unspecified disorder of psychological development
+∞
10.3
10
*
F91.9
ICD-10 Finland
Conduct disorder, unspecified
+∞
10.3
10
*
P98
ICPC
Psychosis NOS/other
+∞
10.3
10
*
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
+∞
10.3
10
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
107.9
10.3
11
*
R4140
NOMESCO Finland
Psychotherapy
107.9
10.3
11
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.4
10.2
50
152
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
4.1
10.2
39
96
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
32.0
10.2
13
*
H50.30
ICD-10 Finland
Intermittent esotropy
6.8
10.2
25
37
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.7
10.1
44
122
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
23.0
10.1
14
6
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
8.7
10.1
21
24
N03AX16
ATC
pregabalin; oral
4.2
10.0
38
93
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
12.9
10.0
17
13
R5140
NOMESCO Finland
Monitoring the use of the aid
6.2
9.9
26
42
P29
ICPC
Psychological sympt/compl other
3.4
9.9
47
140
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
9.8
115
577
E66.01
ICD-10 Finland
Obesity due to excess calories
3.7
9.8
42
115
J45.1
ICD-10 Finland
Nonallergic asthma
2.6
9.7
73
294
Q99.8
ICD-10 Finland
Other specified chromosome abnormalities
19.7
9.6
14
7
G47.3
ICD-10 Finland
Sleep apnoea
3.8
9.4
39
104
WX704
NOMESCO Finland
Intubation
4.2
9.3
35
85
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
9.0
9.3
19
21
H47.2
ICD-10 Finland
Optic atrophy
97.9
9.3
10
*
P07.01
ICD-10 Finland
Extremely low birth weight 500-749 g
97.9
9.3
10
*
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
97.9
9.3
10
*
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
+∞
9.3
9
*
N05AN01
ATC
lithium; oral
+∞
9.3
9
*
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
+∞
9.3
9
*
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
+∞
9.3
9
*
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
+∞
9.3
9
*
F92.0
ICD-10 Finland
Depressive conduct disorder
+∞
9.3
9
*
N03AE01
ATC
clonazepam; systemic
29.5
9.3
12
*
K92.0
ICD-10 Finland
Haematemesis
17.2
9.2
14
8
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
21.3
9.2
13
6
W0A12
NOMESCO Finland
Planned therapy visit for psychiatric disease
21.3
9.2
13
6
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
3.5
9.2
43
127
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
9.4
9.1
18
19
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
9.0
67
268
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
13.5
9.0
15
11
101
Kela drug reimbursment
Anterior pituitary hypofunction
5.4
9.0
26
48
H52.0
ICD-10 Finland
Hypermetropia
3.8
9.0
37
98
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.8
8.9
29
61
RF210
NOMESCO Finland
NA
7.6
8.9
20
26
RS311
NOMESCO Finland
NA
35.9
8.9
11
*
WX892
NOMESCO Finland
Monitored bed care
3.2
8.7
45
143
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
6.0
8.7
23
38
N88
ICPC
Epilepsy
12.3
8.7
15
12
Z63.5
ICD-10 Finland
Disruption of family by separation and divorce
48.9
8.6
10
*
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
48.9
8.6
10
*
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
48.9
8.6
10
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
3.6
8.5
38
108
SPAT1243
SPAT
Psychiatric/psychological examination
3.9
8.5
34
88
Z71.8
ICD-10 Finland
Other specified counselling
1.9
8.4
135
763
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.1
8.4
32
79
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
8.4
87
410
XF404
NOMESCO Finland
Ambulatory ECG
3.4
8.4
39
115
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
6.8
8.4
20
29
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
26.9
8.3
11
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.4
8.3
29
66
BF20A
NOMESCO Finland
NA
19.6
8.3
12
6
F81.1
ICD-10 Finland
Specific spelling disorder
88.0
8.3
9
*
IGY02
SPAT
NA
88.0
8.3
9
*
FDE00
NOMESCO Finland
Closure of patent ductus arteriosus
88.0
8.3
9
*
XCK00
NOMESCO Finland
Perimetry
6.3
8.3
21
33
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.1
8.3
99
500
T90
ICPC
Diabetes non-insulin dependent
5.1
8.3
25
49
K59.09
ICD-10 Finland
Constipation, unspecified
3.5
8.2
37
106
Q93.5
ICD-10 Finland
Other deletions of part of a chromosome
+∞
8.2
8
*
F94.8
ICD-10 Finland
Other childhood disorders of social functioning
+∞
8.2
8
*
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
+∞
8.2
8
*
IBA03
NOMESCO Finland
Psychotherapy evaluation
+∞
8.2
8
*
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
+∞
8.2
8
*
XA820
NOMESCO Finland
NA
+∞
8.2
8
*
F84.0
ICD-10 Finland
Childhood autism
+∞
8.2
8
*
F91.3
ICD-10 Finland
Oppositional defiant disorder
+∞
8.2
8
*
N05AF03
ATC
chlorprothixene; systemic
+∞
8.2
8
*
F20
ICD-10 Finland
Schizophrenia
+∞
8.2
8
*
X78
ICD-10 Finland
Intentional self-harm by sharp object
+∞
8.2
8
*
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
3.7
8.2
35
96
P01
ICPC
Feeling anxious/nervous/tense
2.1
8.2
95
474
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
8.1
123
681
P99
ICPC
Psychological disorders other
9.3
8.1
16
17
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
5.8
8.1
22
38
N03AX11
ATC
topiramate; oral
7.0
8.1
19
27
IEP03
NOMESCO Finland
Focused parental counselling
7.0
8.1
19
27
R4190
NOMESCO Finland
Nutritional therapy
2.5
8.0
64
267
R06.5
ICD-10 Finland
Mouth breathing
2.8
8.0
50
180
XKD00
NOMESCO Finland
Uroflowmetry
4.2
8.0
29
69
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
7.4
8.0
18
24
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.2
8.0
40
125
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.1
8.0
24
47
N06BA09
ATC
atomoxetine; oral
32.6
8.0
10
*
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
5.3
7.9
23
43
N28
ICPC
Limited function/disability (N)
16.8
7.9
12
7
E22.80
ICD-10 Finland
Central precocious puberty
16.8
7.9
12
7
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
3.6
7.9
34
94
K07.24
ICD-10 Finland
Open bite
3.8
7.9
32
84
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
21.6
7.9
11
5
H50.1
ICD-10 Finland
Divergent concomitant strabismus
8.8
7.9
16
18
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
9.9
7.9
15
15
SPAT1262
SPAT
Handing over of treatment supplies
2.9
7.9
47
166
SPAT1396
SPAT
Meeting with multidisciplinary group of experts
4.6
7.8
26
57
N03AF02
ATC
oxcarbazepine; oral
4.4
7.7
27
62
RS120
NOMESCO Finland
NA
12.8
7.7
13
10
ZX120
NOMESCO Finland
Intravenous
2.8
7.7
48
173
301
Kela drug reimbursment
Growth hormone
6.0
7.7
20
33
E66.8
ICD-10 Finland
Other obesity
6.0
7.7
20
33
ZX108
NOMESCO Finland
Inhalation
8.3
7.6
16
19
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
8.3
7.6
16
19
N06AX12
ATC
bupropion; oral
5.3
7.6
22
41
TAB00
NOMESCO Finland
Lumbar puncture
3.9
7.6
30
77
N29
ICPC
Neurological sympt/complt other
10.6
7.6
14
13
L28
ICPC
Limited function/disability (L)
3.3
7.6
37
113
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
4.3
7.6
27
63
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
14.7
7.6
12
8
C03DA01
ATC
spironolactone; oral
4.8
7.6
24
50
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
4.4
7.5
26
59
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
7.3
7.5
17
23
E34.31
ICD-10 Finland
Short stature, prenatal disorder
7.3
7.5
17
23
DFF20
NOMESCO Finland
Audiometry for children
5.2
7.5
22
42
P07.02
ICD-10 Finland
Extremely low birth weight 750-999 g
24.4
7.4
10
*
RS140
NOMESCO Finland
NA
24.4
7.4
10
*
H03AA01
ATC
levothyroxine sodium; systemic
2.7
7.4
50
189
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
5.7
7.3
20
35
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
78.1
7.3
8
*
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
78.1
7.3
8
*
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
78.1
7.3
8
*
ICC01
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric outpatient clinic
78.1
7.3
8
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.9
7.3
43
151
F28
ICD-10 Finland
Other nonorganic psychotic disorders
+∞
7.2
7
*
N05AE05
ATC
lurasidone; oral
+∞
7.2
7
*
RT121
NOMESCO Finland
NA
+∞
7.2
7
*
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
+∞
7.2
7
*
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
+∞
7.2
7
*
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
+∞
7.2
7
*
AA400
NOMESCO Finland
Electroconvulsive therapy
+∞
7.2
7
*
3153X
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[PUHEEN KEHITYKSEN ERITYISVAIKEUS]
+∞
7.2
7
*
3159X
ICD-9 Finland
Specific delays in development, Unspecified delay in development
+∞
7.2
7
*
IER01
NOMESCO Finland
Psychoeducation, group
+∞
7.2
7
*
P07.3
ICD-10 Finland
Other preterm infants
3.2
7.2
36
113
SPAT1395
SPAT
Health check-up of persons outside student and working life
10.6
7.1
13
12
H50.2
ICD-10 Finland
Vertical strabismus
15.4
7.1
11
7
N05CF01
ATC
zopiclone; oral
3.5
7.1
32
93
H66.9
ICD-10 Finland
Otitis media, unspecified
1.8
7.1
126
737
RT190
NOMESCO Finland
NA
29.3
7.0
9
*
DFF00
NOMESCO Finland
Pure tone audiometry
3.4
7.0
33
99
A02BC02
ATC
pantoprazole; systemic
1.9
7.0
119
684
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
6.9
223
1554
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.3
6.9
24
55
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
11.8
6.9
12
10
G40.10
ICD-10 Finland
Simple partial seizures
11.8
6.9
12
10
NE1AA
NOMESCO Finland
Pelvis X-ray examination
5.0
6.9
21
42
A11CC03
ATC
alfacalcidol; systemic
5.9
6.9
18
30
RK220
NOMESCO Finland
NA
8.6
6.9
14
16
SPAT1281
SPAT
Other administrative function
2.4
6.8
59
256
ZX114
NOMESCO Finland
Intramuscular
6.2
6.8
17
27
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.8
6.8
27
71
G40.89
ICD-10 Finland
Other epilepsy
13.5
6.8
11
8
C07AB07
ATC
bisoprolol; oral
2.7
6.7
46
174
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.5
6.7
29
82
XG413
NOMESCO Finland
Spirometry with oscillometry
3.9
6.7
26
67
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.8
6.7
129
775
TLC00
NOMESCO Finland
Insertion of intrauterine device
4.7
6.7
21
44
N05AB03
ATC
perphenazine; systemic, rectal
38.9
6.7
8
*
XX4BW
NOMESCO Finland
NA
9.1
6.6
13
14
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
9.1
6.6
13
14
BC00A
NOMESCO Finland
NA
16.3
6.6
10
6
P24
ICPC
Specific learning problem
3.3
6.6
31
93
M79.6
ICD-10 Finland
Pain in limb
1.9
6.6
111
636
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
22.0
6.6
9
*
D09
ICPC
Nausea
2.3
6.5
59
260
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
4.0
6.5
24
59
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.8
6.5
26
69
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.7
6.5
14
18
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
5.8
6.4
17
29
Q38.1
ICD-10 Finland
Ankyloglossia
4.2
6.4
23
55
NF1DA
NOMESCO Finland
X-ray of hips
9.8
6.4
12
12
R51.80
ICD-10 Finland
Headache
2.0
6.4
89
477
F80.0
ICD-10 Finland
Specific speech articulation disorder
6.7
6.4
15
22
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
6.7
6.4
15
22
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.7
6.4
15
22
Z11
ICPC
Compliance/being ill problem
68.0
6.3
7
*
RS231
NOMESCO Finland
NA
68.0
6.3
7
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
68.0
6.3
7
*
Q04.8
ICD-10 Finland
Other specified congenital malformations of brain
68.0
6.3
7
*
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
68.0
6.3
7
*
RT120
NOMESCO Finland
NA
68.0
6.3
7
*
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
68.0
6.3
7
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.1
6.3
23
56
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
14.0
6.3
10
7
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
14.0
6.3
10
7
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.0
6.2
35
118
ZX121
NOMESCO Finland
Central venous catheter
8.0
6.2
13
16
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
8.0
6.2
13
16
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
8.0
6.2
13
16
RT320
NOMESCO Finland
NA
+∞
6.2
6
*
RT250
NOMESCO Finland
NA
+∞
6.2
6
*
IEY19
NOMESCO Finland
Psychiatric health counselling and guidance
+∞
6.2
6
*
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
+∞
6.2
6
*
Z72.8
ICD-10 Finland
Other problems related to lifestyle
+∞
6.2
6
*
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
+∞
6.2
6
*
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
+∞
6.2
6
*
IEY15
NOMESCO Finland
Acute psychiatry, stabilising intervention
+∞
6.2
6
*
N05AE04
ATC
ziprasidone; systemic
+∞
6.2
6
*
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
+∞
6.2
6
*
RL720
NOMESCO Finland
NA
+∞
6.2
6
*
IEY08
NOMESCO Finland
Psychiatric coaching, domestic and community skills
+∞
6.2
6
*
F21
ICD-10 Finland
Schizotypal disorder
+∞
6.2
6
*
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
+∞
6.2
6
*
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
10.8
6.2
11
10
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.4
6.1
49
204
S03.22
ICD-10 Finland
Exarticulation of tooth
17.6
6.1
9
5
F41.8
ICD-10 Finland
Other specified anxiety disorders
5.4
6.1
17
31
Z61.7
ICD-10 Finland
Personal frightening experience in childhood
26.0
6.1
8
*
R27.0
ICD-10 Finland
Ataxia, unspecified
26.0
6.1
8
*
Z61.8
ICD-10 Finland
Other negative life events in childhood
26.0
6.1
8
*
RF430
NOMESCO Finland
NA
26.0
6.1
8
*
H02AB09
ATC
hydrocortisone; systemic
3.1
6.1
31
100
H81
ICPC
Excessive ear wax
2.6
6.0
42
161
F43.8
ICD-10 Finland
Other reactions to severe stress
6.2
6.0
15
24
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
328
1524
3.27
45.43
15.4
10.5
1.2
1.2
mmol/l
1.73
308
1416
317
1456
3.24
44.54
17.4
11.8
1.2
1.2
mmol/l
1.83
308
1388
276
1237
3.06
39.27
4.7
3.1
68.5
69.1
nmol/l
0.13
263
1181
376
2000
3.06
39.23
7.2
5.6
123.8
113.5
u/l
1.43
357
1880
174
647
3.19
33.47
3.1
3.0
2.4
2.4
mmol/l
1.48
160
578
104
285
3.99
31.87
14.2
17.5
1.3
1.5
mmol/l
0.46
95
264
29
0
+∞
29.93
14.6
0.0
18725.7
—
nmol/l
—
29
0
222
1028
2.67
27.74
9.4
8.6
37.9
38.1
g/l
0.14
210
980
426
2736
2.60
25.89
4.5
3.0
14.6
14.5
pmol/l
0.35
396
2435
200
905
2.65
25.89
4.8
4.7
40.8
34.6
u/l
0.46
195
866
147
567
2.94
25.85
1.8
1.4
98.5
99.3
pmol/l
0.07
70
283
506
3553
3.09
25.57
20.4
9.5
139.6
139.4
mmol/l
2.32
495
3413
241
1204
2.50
25.26
8.7
7.3
21.3
20.7
umol/l
0.08
226
1101
505
3558
3.04
25.03
20.3
9.5
4.0
3.9
mmol/l
0.66
493
3399
161
663
2.79
24.98
13.7
10.1
1.3
1.4
mmol/l
0.71
153
630
320
1891
2.29
22.08
10.7
6.7
5.9
6.2
mmol/l
2.45
304
1717
466
3237
2.57
22.06
5.0
3.2
2.0
2.0
mu/l
0.56
442
3025
114
425
2.92
21.00
15.4
12.2
0.8
0.8
mmol/l
0.49
108
407
88
285
3.27
20.63
1.4
1.2
20.2
19.8
nmol/l
0.09
81
261
389
2557
2.24
19.88
14.3
9.7
3.6
3.5
e9/l
0.54
343
2119
163
747
2.48
19.85
8.6
9.5
0.8
1.1
mmol/l
0.75
132
591
365
2350
2.20
19.49
3.8
1.8
5.7
5.4
mmol/l
3.72
343
2156
523
3971
2.78
18.28
11.7
7.3
32.8
27.1
u/l
2.18
511
3821
99
379
2.78
17.19
2.2
1.3
1.7
1.2
%
1.20
92
346
333
2146
2.06
16.75
4.5
2.9
36.5
36.6
mmol/mol
0.01
322
2037
141
661
2.35
15.97
4.1
3.3
4.5
1.6
e6/l
2.14
86
367
150
727
2.28
15.70
3.2
2.7
1.0
1.0
kg/l
0.05
27
145
103
421
2.61
15.66
5.6
7.3
6.0
6.6
umol/l
0.17
89
346
18
17
10.38
15.63
3.7
3.9
1.2
1.0
umol/l
0.90
18
17
81
300
2.82
14.89
2.8
2.0
4.6
5.8
u/l
1.16
60
202
61
192
3.26
14.87
19.6
14.5
-0.4
0.0
mmol/l
0.26
49
158
31
63
4.89
13.71
3.5
4.4
1.7
1.8
umol/l
0.20
31
63
15
14
10.46
13.07
4.6
2.2
26.7
28.6
umol/l
0.17
15
14
104
469
2.34
12.67
3.8
2.7
12.9
14.3
umol/l
1.11
95
452
143
739
2.10
12.47
17.3
7.7
5.0
5.0
kpa
0.10
138
713
346
2407
1.86
12.38
10.2
8.0
51.1
49.9
%
1.00
334
2301
97
430
2.37
12.27
3.8
2.7
2.6
2.5
g/l
0.24
86
415
142
736
2.10
12.27
17.3
7.7
0.4
0.9
mmol/l
1.25
105
533
117
564
2.21
12.15
1.8
1.9
1.6
1.2
mmol/l
2.67
108
518
79
320
2.56
12.13
2.6
1.8
9.5
12.0
nmol/l
1.16
65
276
349
2453
1.83
11.88
10.5
8.2
34.0
35.0
%
0.90
337
2340
210
1261
1.90
11.86
5.9
3.8
—
—
—
0
0
370
2650
1.84
11.82
3.9
2.4
4.3
4.4
mmol/l
2.30
354
2528
131
669
2.11
11.72
4.2
3.2
0.5
0.7
e6/l
0.59
75
368
514
4134
2.17
11.24
22.9
12.0
13.3
13.1
%
5.31
506
4054
364
2618
1.81
11.21
3.8
2.3
2.7
2.7
mmol/l
0.20
350
2474
351
2498
1.80
11.19
3.6
2.3
1.3
1.1
mmol/l
4.56
335
2386
75
314
2.46
10.72
14.1
5.9
868.1
801.7
ng/l
0.11
58
254
69
281
2.51
10.45
2.9
2.0
6.0
6.3
iu/l
0.13
51
188
88
405
2.25
10.14
4.2
2.8
19.7
23.4
%
1.89
83
383
358
2607
1.75
10.11
3.7
2.3
1.2
1.4
mmol/l
13.24
345
2476
15
20
7.31
10.00
1.8
1.1
—
—
—
0
0
336
2418
1.72
9.76
8.9
5.3
113.8
109.6
ml/min/173m2
2.82
229
1663
42
137
3.07
9.65
1.5
1.6
990.6
1027.3
nmol/l
0.09
32
101
146
827
1.90
9.57
3.4
2.8
—
—
—
0
0
114
599
2.00
9.29
6.4
4.0
1.2
1.7
mg/l
0.59
85
404
89
429
2.15
9.12
5.1
3.0
759.9
1562.8
ng/l
1.00
56
243
125
689
1.92
8.84
17.0
7.6
9.8
9.8
kpa
0.17
119
669
40
134
2.98
8.79
26.3
18.5
92.4
96.2
%
0.91
40
134
32
94
3.37
8.71
14.7
13.4
22.3
23.0
mmol/l
0.70
32
86
33
99
3.31
8.69
3.3
2.9
11.1
11.0
%
0.03
28
91
176
1090
1.76
8.52
5.7
3.4
0.2
0.2
e6/l
0.41
131
810
60
256
2.37
8.21
2.1
2.7
23.0
37.8
u/l
3.51
49
213
39
134
2.90
8.20
26.8
18.5
0.6
0.7
%
1.61
39
134
297
2134
1.64
8.13
5.0
3.4
35.5
27.3
u/l
1.87
290
2052
52
209
2.50
8.09
2.4
2.5
2.4
2.4
mmol/l
0.04
40
173
108
585
1.93
8.00
9.1
6.1
31.0
30.8
s
0.08
108
577
66
306
2.19
7.44
2.4
1.8
—
—
—
0
0
31
99
3.09
7.40
3.2
2.7
0.3
0.2
e9/l
0.30
24
62
31
99
3.09
7.40
3.2
2.7
657.8
527.2
e6/l
0.49
24
60
41
155
2.63
7.23
4.7
2.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
24
67
3.52
7.07
26.0
25.7
0.3
0.4
u/ml
0.90
15
38
65
306
2.15
7.05
2.7
1.9
—
—
—
0
0
31
103
2.97
6.94
5.1
8.5
24.2
24.2
mmol/l
0.02
31
98
30
98
3.02
6.91
3.4
3.0
—
—
—
0
0
303
2252
1.56
6.76
5.4
3.2
163.4
52.1
e6/l
—
10
24
28
89
3.10
6.75
4.9
5.6
88.1
94.5
%
0.62
28
89
9
5
17.40
6.12
1.0
1.2
—
—
—
0
0
211
1485
1.54
5.78
5.4
4.2
—
—
—
0
0
137
872
1.64
5.74
3.8
3.5
2.8
2.5
mg/l
0.80
125
782
35
138
2.51
5.71
1.7
1.3
—
—
—
0
0
77
417
1.87
5.66
2.6
1.9
—
—
—
0
0
510
4357
1.71
5.65
16.0
8.6
22.6
23.6
mg/l
0.24
387
2953
13
27
4.67
5.61
2.2
1.7
20.8
20.0
nmol/l
—
5
8
11
20
5.33
5.47
8.4
7.8
—
—
—
0
0
48
222
2.15
5.47
2.3
1.7
—
—
—
0
0
323
2520
1.47
5.21
5.1
3.9
8.1
7.0
mm/h
0.99
307
2331
83
473
1.78
5.18
1.5
1.4
228.5
403.3
u/ml
0.86
77
449
32
127
2.48
5.17
2.5
4.4
9.3
7.3
e6/l
0.09
24
88
32
128
2.46
5.09
2.6
4.4
35.9
90.2
e6/l
0.46
26
91
90
529
1.73
5.05
3.1
2.0
74.5
42.8
ng/l
0.38
45
181
32
130
2.42
4.93
1.5
1.4
—
—
—
0
0
21
71
2.89
4.61
1.5
1.4
—
—
—
0
0
31
129
2.36
4.55
2.3
4.1
3.3
3.4
mmol/l
0.55
31
122
18
56
3.13
4.54
4.2
5.1
24.0
24.7
umol/l
0.13
18
56
28
112
2.45
4.47
2.1
3.2
85.2
97.5
ml/min/173m2
—
7
31
233
1745
1.44
4.45
4.0
2.9
0.0
0.0
estimate
0.00
20
311
32
137
2.30
4.41
3.8
2.4
14.5
14.9
mu/l
0.08
32
127
8
255
0.29
4.23
1.5
1.7
—
—
—
0
0
23
87
2.58
4.12
2.5
1.5
—
—
—
0
0
11
26
4.09
4.08
5.5
6.2
—
—
—
0
0
11
26
4.09
4.08
6.4
6.3
—
—
—
0
0
20
71
2.74
4.04
5.7
6.0
2.6
1.9
ug/l
0.49
20
71
230
1744
1.41
4.01
5.7
4.3
0.0
0.0
estimate
0.00
25
329
243
1862
1.41
3.98
3.9
2.9
65.0
64.2
ug/l
0.03
235
1775
476
4904
0.67
3.98
3.7
3.8
—
—
—
0
0
8
245
0.30
3.95
1.4
1.5
—
—
—
0
0
229
1756
1.39
3.67
4.1
3.0
0.0
0.0
estimate
0.00
25
322
30
136
2.16
3.65
3.9
2.2
—
—
—
0
0
11
30
3.54
3.39
1.2
1.1
—
—
—
0
0
11
30
3.54
3.39
9.6
8.9
—
—
—
0
0
9
17
5.11
3.38
1.4
1.6
651.3
292.2
mu/l
—
9
17
23
98
2.29
3.25
2.7
1.8
—
—
—
0
0
9
18
4.83
3.24
1.4
1.6
72.7
74.4
%
—
9
18
58
343
1.68
3.21
1.6
1.3
137.8
154.1
iu/ml
0.09
12
121
22
93
2.30
3.17
2.2
1.9
—
—
—
0
0
22
93
2.30
3.17
3.2
1.8
—
—
—
0
0
14
47
2.89
3.15
17.2
9.3
9.6
8.2
mg/l
0.30
14
42
26
119
2.13
3.12
1.7
1.4
5.8
8.0
ug/l
0.41
26
114
28
132
2.07
3.12
3.5
2.0
—
—
—
0
0
9
19
4.57
3.11
27.1
8.0
1.2
1.2
mmol/l
—
9
14
8
15
5.14
3.07
3.4
4.0
—
—
—
0
0
122
863
1.44
3.04
3.7
3.0
0.0
0.0
estimate
0.50
25
309
20
83
2.34
3.01
1.5
1.4
—
—
—
0
0
12
39
2.97
2.86
2.4
2.0
164.1
115.2
%
1.19
12
39
13
45
2.79
2.79
3.3
2.6
1.5
1.6
mmol/l
0.55
13
45
11
267
0.38
2.73
1.5
1.7
—
—
—
0
0
523
4682
1.46
2.72
22.7
11.1
40.1
40.2
%
0.03
459
4201
9
23
3.77
2.65
3.1
5.3
167.6
211.7
ug/l
—
9
23
22
402
0.50
2.62
1.1
1.2
—
—
—
0
0
11
36
2.95
2.60
1.5
1.1
—
—
—
0
0
52
317
1.62
2.60
9.2
6.5
252.3
309.8
u/l
1.39
52
307
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
42
2.76
2.53
1.5
1.1
—
—
—
0
0
11
37
2.87
2.48
2.5
4.8
18.2
25.0
ug/l
1.23
11
37
13
49
2.56
2.40
4.5
5.2
—
—
—
0
0
7
16
4.21
2.37
2.0
2.0
—
—
—
0
0
210
1678
1.30
2.35
1.5
1.8
0.4
3.5
u/ml
7.15
39
308
10
33
2.92
2.33
1.2
1.1
—
—
—
0
0
31
170
1.78
2.29
3.2
1.8
30.3
33.2
%
0.66
21
126
17
75
2.20
2.27
3.9
1.9
1.5
2.2
mmol/l
—
10
59
12
45
2.58
2.25
1.1
1.1
—
—
—
0
0
17
318
0.50
2.20
1.7
1.9
—
—
—
0
0
24
123
1.90
2.19
1.4
1.3
—
—
—
0
0
24
123
1.90
2.19
1.4
1.3
—
—
—
0
0
12
46
2.52
2.16
1.1
1.1
—
—
—
0
0
187
2110
0.78
2.16
2.0
1.9
—
—
—
0
0
19
90
2.05
2.15
2.7
1.8
—
—
—
0
0
15
65
2.23
2.10
2.5
1.6
—
—
—
0
0
11
41
2.59
2.09
1.5
1.1
—
—
—
0
0
13
53
2.37
2.07
3.1
2.8
17.5
18.4
%
—
7
28
6
14
4.12
2.06
2.3
2.6
—
—
—
0
0
5
10
4.80
1.99
4.2
3.5
—
—
—
0
0
34
506
0.62
1.99
1.5
1.6
—
—
—
0
0
9
32
2.71
1.89
1.0
1.2
262.9
268.7
mg/l
—
9
26
11
44
2.41
1.83
3.2
1.3
—
—
—
0
0
11
44
2.41
1.83
1.0
1.1
—
—
—
0
0
8
27
2.85
1.83
2.0
1.4
—
—
—
0
0
8
28
2.75
1.76
1.0
1.1
—
—
—
0
0
35
498
0.65
1.70
1.4
1.5
—
—
—
0
0
11
46
2.31
1.68
3.1
1.7
—
—
—
0
0
35
219
1.56
1.64
2.8
1.9
—
92.7
—
0
19
16
82
1.88
1.51
2.4
1.8
2.4
6.5
iu/l
—
6
31
6
20
2.88
1.50
1.3
1.7
—
—
—
0
0
6
20
2.88
1.50
1.3
1.7
—
—
—
0
0
6
20
2.88
1.50
1.3
1.7
—
—
—
0
0
155
1258
1.24
1.45
3.4
2.7
—
—
—
0
0
54
382
1.38
1.40
2.7
2.6
7591.8
4837.7
u/l
0.19
13
159
14
71
1.90
1.37
1.6
1.4
9.0
1.9
u/ml
—
8
31
27
169
1.55
1.30
1.4
1.1
—
—
—
0
0
5
17
2.82
1.29
1.0
1.4
—
—
—
0
0
15
80
1.81
1.28
3.1
1.6
—
—
—
0
0
5
18
2.66
1.22
1.2
2.1
—
—
—
0
0
14
75
1.80
1.18
1.1
1.1
—
—
—
0
0
8
38
2.02
1.12
3.4
1.8
—
—
—
0
0
7
31
2.17
1.07
1.3
1.7
7.1
9.3
umol/l
—
7
31
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
7
31
2.17
1.07
2.1
1.2
79.7
89.2
%
—
7
31
6
27
2.13
0.91
1.0
2.1
—
—
—
0
0
28
193
1.40
0.90
2.4
1.9
—
—
—
0
0
6
28
2.05
0.88
2.2
1.2
—
—
—
0
0
8
45
1.71
0.80
1.8
1.8
—
—
—
0
0
11
63
1.68
0.78
3.1
1.7
—
—
—
0
0
13
188
0.65
0.76
1.0
1.1
—
8.1
—
0
32
5
22
2.18
0.76
1.0
1.8
—
—
—
0
0
35
260
1.30
0.73
1.9
2.2
—
11.2
—
0
23
135
1428
0.87
0.69
2.7
2.4
—
—
—
0
0
7
42
1.60
0.65
2.1
1.3
—
—
—
0
0
67
548
1.19
0.62
1.1
1.1
—
—
—
0
0
38
295
1.24
0.59
2.7
1.7
—
—
—
0
0
10
61
1.57
0.58
1.4
1.5
—
—
—
0
0
6
33
1.74
0.58
1.2
1.1
—
—
—
0
0
6
33
1.74
0.58
1.3
1.3
—
—
—
0
0
6
34
1.69
0.57
1.3
1.2
—
—
—
0
0
128
1340
0.89
0.56
2.4
2.2
—
—
—
0
0
6
35
1.64
0.56
1.3
1.3
—
—
—
0
0
37
289
1.24
0.55
2.8
1.8
165.2
150.1
u/ml
0.13
20
138
17
217
0.74
0.54
2.1
2.0
—
—
—
0
0
9
58
1.49
0.54
1.1
1.2
—
—
—
0
0
14
182
0.73
0.51
1.9
1.5
0.0
0.1
iu/ml
—
7
49
8
111
0.68
0.46
1.3
1.3
—
—
—
0
0
7
47
1.43
0.46
1.3
1.8
8.4
6.6
mmol/l
—
7
35
5
30
1.60
0.42
1.0
1.4
—
—
—
0
0
5
30
1.60
0.42
1.0
1.4
—
—
—
0
0
5
30
1.60
0.42
1.0
1.4
—
—
—
0
0
6
90
0.63
0.42
1.7
1.7
—
—
—
0
0
5
31
1.54
0.42
2.8
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
32
1.49
0.41
1.0
1.1
2497.4
1823.7
miu/ml
—
5
32
5
32
1.49
0.41
1.0
1.5
—
—
—
0
0
5
32
1.49
0.41
1.0
1.5
—
—
—
0
0
25
195
1.23
0.40
1.3
1.3
—
—
—
0
0
0
18
0.00
0.39
0.0
1.4
—
—
—
0
0
26
298
0.83
0.39
1.4
1.3
—
—
—
0
0
29
326
0.84
0.36
1.4
1.4
—
—
—
0
0
10
126
0.75
0.32
1.3
1.2
—
—
—
0
0
21
167
1.21
0.30
1.0
1.0
10.2
9.5
mu/l
0.19
15
135
11
80
1.32
0.30
1.9
2.4
—
—
—
0
0
7
54
1.24
0.29
1.1
1.1
—
—
—
0
0
14
108
1.24
0.26
5.2
2.6
—
—
—
0
0
46
397
1.11
0.25
1.5
1.3
—
—
—
0
0
11
83
1.27
0.24
2.7
3.0
134.2
135.4
g/l
0.07
11
69
22
242
0.86
0.23
1.5
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
9.3
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
25
211
1.14
0.20
1.1
1.1
4.1
9.9
u/ml
0.93
12
133
89
806
1.06
0.18
2.5
2.2
—
—
—
0
0
29
305
0.90
0.17
1.2
1.4
—
—
—
0
0
5
63
0.76
0.17
1.6
1.3
—
—
—
0
0
5
63
0.76
0.17
1.8
1.4
—
—
—
0
0
5
65
0.73
0.17
9.0
2.6
—
—
—
0
0
8
67
1.14
0.16
1.3
1.2
—
—
—
0
0
29
303
0.91
0.15
1.2
1.2
—
—
—
0
0
6
75
0.76
0.15
1.3
1.9
8.3
6.9
mmol/l
—
6
47
26
226
1.10
0.14
1.2
1.1
3.7
9.4
u/ml
1.46
14
136
17
180
0.90
0.11
1.1
1.1
—
—
—
0
0
75
687
1.05
0.11
2.1
2.0
—
—
—
0
0
16
167
0.91
0.08
1.4
1.2
—
—
—
0
0
5
58
0.82
0.08
1.0
1.4
—
—
—
0
0
46
422
1.04
0.07
1.2
1.3
3.4
1.9
u/ml
0.33
28
277
9
96
0.89
0.06
1.0
1.5
—
—
—
0
0
9
97
0.88
0.06
1.7
1.8
—
—
—
0
0
43
423
0.97
0.04
1.2
1.2
13.8
16.6
iu/ml
—
8
100
40
373
1.02
0.02
1.1
1.2
3.9
4.7
u/ml
0.11
14
125
13
131
0.95
0.02
1.6
1.1
—
—
—
0
0
21
206
0.97
0.00
1.5
1.4
—
—
—
0
0
21
206
0.97
0.00
1.5
1.5
—
—
—
0
0
27
263
0.98
0.00
1.7
1.8
—
—
—
0
0
28
269
0.99
0.00
1.4
1.3
330.1
252.2
miu/ml
0.39
11
141
13
127
0.98
0.00
1.6
1.1
—
—
—
0
0
12
115
1.00
0.00
1.2
1.4
52.4
15.7
u/ml
—
7
95
18
172
1.00
0.00
3.2
1.9
—
—
—
0
0
13
128
0.97
0.00
1.0
1.0
6.7
7.3
kpa
—
7
100
42
397
1.01
0.00
1.2
1.2
0.9
8.8
u/ml
1.90
14
121
21
204
0.98
0.00
1.5
1.4
—
—
—
0
0
21
205
0.98
0.00
1.5
1.4
—
—
—
0
0
13
123
1.01
0.00
1.1
1.1
—
—
—
0
0
13
126
0.98
0.00
1.0
1.0
3.5
3.4
kpa
—
7
98
21
198
1.01
0.00
1.0
1.1
0.9
0.4
u/ml
—
9
91
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
9
89
0.96
0.00
1.0
2.0
41.0
39.0
u/l
—
9
84
6
58
0.99
0.00
1.0
1.5
—
1.3
—
0
5
0
7
0.00
0.00
0.0
2.0
—
2.1
—
0
7
5
53
0.90
0.00
3.2
2.0
—
—
—
0
0
7
72
0.93
0.00
1.0
1.4
—
40.7
—
0
9
5
52
0.92
0.00
1.0
1.0
175.6
163.1
g/l
—
5
52
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
48
0.99
0.00
1.4
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint KRA_PSY_MOTOR_EXMORE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| KRA_PSY_MOTOR_EXMORE | 5.423 [3.53, 8.32] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.718 |
During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 4619 females with KRA_PSY_MOTOR_EXMORE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| KRA_PSY_MOTOR_EXMORE | 1.391 [1.09, 1.78] | 0.009 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 12381 males with KRA_PSY_MOTOR_EXMORE died.
Mortality risk
Mortality risk for people of age
years, who have KRA_PSY_MOTOR_EXMORE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.535% | 0.22% |
| 5 | 3.684% | 1.348% |
| 10 | 8.492% | 3.597% |
| 15 | 15.025% | 6.466% |
| 20 | 25.122% | 10.711% |
Relationships between endpoints
↥Index endpoint: KRA_PSY_MOTOR_EXMORE – Motor disorders, excluding more controls
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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