Mixed specific developmental disorders

F5_MIXEDDEV

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F83
  • Cause of death: ICD-10 F83

2 out of 7 registries used, show all original rules.

908

4. Check minimum number of events

None

908

5. Include endpoints

None

908

6. Filter based on genotype QC (FinnGen only)

817

Control definitions (FinnGen only)

Control exclude
F5_PSYCHDEV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F80-F89
Name in latin
Perturbationes progressus specificae mixtae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 32334 9898 22428
Only index persons 24048 7389 16659
Unadjusted period prevalence (%)
Whole population 0.52 0.28 0.63
Only index persons 0.52 0.27 0.64
Median age at first event (years)
Whole population 5.94 6.11 5.86
Only index persons 6.45 6.68 6.35

-FinnGen-

Key figures

All Female Male
Number of individuals 817 353 464
Unadjusted period prevalence (%) 0.17 0.13 0.21
Median age at first event (years) 6.71 7.46 6.15

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
900
Matched controls
8309
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F83
ICD-10 Finland
Mixed specific developmental disorders
+∞
307.7
900
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
165.6
305.0
162
11
R62.0
ICD-10 Finland
Delayed milestone
26.0
279.3
218
101
XA800
NOMESCO Finland
Neuropsychological investigation
18.6
270.3
250
168
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
19.5
185.3
160
91
Z2445
NOMESCO Finland
Psychologist
8.3
158.4
259
386
F82
ICD-10 Finland
Specific developmental disorder of motor function
298.8
157.3
160
6
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.9
128.4
246
429
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
20.2
118.1
98
50
N05AX08
ATC
risperidone; systemic
8.6
117.4
172
221
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
255.2
116.3
120
5
F80.1
ICD-10 Finland
Expressive language disorder
311.2
114.5
117
*
F80.2
ICD-10 Finland
Receptive language disorder
270.9
100.9
104
*
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
180.6
98.4
104
6
P85
ICPC
Mental retardation
20.9
94.8
77
37
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
44.8
92.7
59
13
N03AG01
ATC
valproic acid; systemic, rectal
7.4
92.1
153
225
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.8
89.8
161
257
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.6
89.6
286
766
Z2446
NOMESCO Finland
Social worker
4.8
88.6
256
633
RL140, ,
NOMESCO Finland
26.2
82.3
61
23
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
216.3
81.2
85
*
R4120
NOMESCO Finland
Occupational therapy
7.1
80.0
136
204
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
5.1
80.0
207
464
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.6
77.5
141
227
Z31.5
ICD-10 Finland
Genetic counselling
5.7
76.5
165
314
Z50.5
ICD-10 Finland
Speech therapy
7.8
76.4
117
156
RL130, ,
NOMESCO Finland
25.5
76.2
57
22
F84.5
ICD-10 Finland
Asperger syndrome
36.7
73.4
49
13
Z3226
NOMESCO Finland
Physiotherapist
3.9
73.1
299
944
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
6.5
71.9
132
214
F90.0
ICD-10 Finland
Disturbance of activity and attention
4.3
70.1
224
590
RT150, ,
NOMESCO Finland
17.8
66.9
58
32
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
6.1
65.9
128
219
R1260
NOMESCO Finland
Evaluation of communicative skills
16.6
65.7
59
35
N05AX12
ATC
aripiprazole; systemic
5.7
62.6
132
244
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
161.5
60.8
65
*
N05BA09
ATC
clobazam; oral
10.9
60.6
70
64
N06BA04
ATC
methylphenidate; oral
4.1
58.2
195
527
183
Kela drug reimbursment
Lamotrigin and topiramate
13.2
58.0
59
44
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
32.2
57.7
40
12
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.4
57.2
276
952
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.9
56.6
84
107
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.4
53.5
259
891
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
11.4
52.1
58
50
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.6
51.5
107
194
R1250
NOMESCO Finland
Evaluation of functional capability
15.0
51.0
48
31
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
8.4
50.8
71
84
EBA15
NOMESCO Finland
Extraction of multiple teeth
7.5
50.5
78
104
R4130
NOMESCO Finland
Speech therapy
7.9
50.4
74
93
N05BA01
ATC
diazepam; systemic, rectal
4.8
50.0
127
275
N03AX09
ATC
lamotrigine; oral
5.4
49.2
108
206
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
14.3
48.6
47
32
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.3
47.3
140
342
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
101.8
46.7
52
5
N03AX14
ATC
levetiracetam; systemic
7.3
45.7
72
98
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.5
45.7
191
594
F84.8
ICD-10 Finland
Other pervasive developmental disorders
444.9
45.3
46
*
N05CD08
ATC
midazolam; nasal, systemic
6.7
44.9
77
115
F84.0
ICD-10 Finland
Childhood autism
+∞
44.9
44
*
N03AF02
ATC
oxcarbazepine; oral
6.0
44.1
85
143
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.1
43.4
99
195
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
218.4
42.9
45
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
42.7
271
1074
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
42.5
224
800
A28
ICPC
Limited function/disability NOS
4.8
41.9
104
220
RT160, ,
NOMESCO Finland
12.2
41.5
44
35
N05AH03
ATC
olanzapine; systemic
4.2
41.4
122
296
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.8
41.1
145
401
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.7
40.5
147
414
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
5.3
40.3
89
170
P24
ICPC
Specific learning problem
5.5
39.8
84
154
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
18.1
39.7
34
18
IGV01
NOMESCO Finland
Psychiatric network contact
6.1
38.2
71
115
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
9.9
37.8
46
45
DFF20
NOMESCO Finland
Audiometry for children
7.7
35.8
53
67
H50.31
ICD-10 Finland
Intermittent exotropia
6.7
34.7
58
84
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.3
33.6
95
222
R5599
NOMESCO Finland
Other rehabilitation service
6.7
33.5
56
81
Z3231
NOMESCO Finland
Registered nurse
2.4
33.5
357
1788
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.6
33.2
126
364
RS222, ,
NOMESCO Finland
8.8
32.6
43
47
Z3229
NOMESCO Finland
Other healthcare associate professional
3.5
32.5
129
383
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
32.4
291
1345
Z2221
NOMESCO Finland
Medical doctor
2.5
31.8
269
1208
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
10.4
31.7
37
34
N03AX11
ATC
topiramate; oral
6.0
31.5
59
96
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
31.1
341
1717
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.0
30.5
96
243
N05AH02
ATC
clozapine; systemic
6.8
30.4
50
71
ZY010
NOMESCO Finland
Hospital outpatient
3.2
30.1
137
442
N05AH04
ATC
quetiapine; oral
2.6
29.7
217
905
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
28.9
129
411
P22
ICPC
Child behaviour symptom/complaint
3.8
28.6
94
245
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
9.6
28.3
35
35
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.3
27.7
115
350
R4110
NOMESCO Finland
Physiotherapy
2.4
27.5
251
1157
H01AC01
ATC
somatropin; parenteral
4.9
26.5
62
124
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
3.3
26.5
108
325
F88
ICD-10 Finland
Other disorders of psychological development
51.0
26.3
32
6
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.1
25.8
124
412
RT490, ,
NOMESCO Finland
26.6
25.8
36
13
XX4AW, ,
NOMESCO Finland
6.1
25.2
46
73
R5140
NOMESCO Finland
Monitoring the use of the aid
5.3
25.0
53
97
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
88.9
24.9
28
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.3
24.8
104
318
F20.9
ICD-10 Finland
Schizophrenia, unspecified
7.5
24.8
37
47
K03.66
ICD-10 Finland
Tooth plaque
2.5
24.5
187
789
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.4
24.4
95
277
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
24.1
83
223
ZXE00
NOMESCO Finland
One hour or less
2.1
24.0
371
2095
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
5.2
23.9
51
94
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.1
23.8
69
164
F70
ICD-10 Finland
Mild mental retardation
+∞
23.3
23
*
SPAT1229
SPAT
Assessment of need for aid
6.2
23.1
41
63
N05AA02
ATC
levomepromazine; systemic
5.8
23.0
44
73
F79.1
ICD-10 Finland
Unspecified mental retardation, significant impairment of behaviour requiring attention or treatment
39.4
22.8
29
7
IEV99
NOMESCO Finland
Other psychiatric network intervention
5.3
22.6
48
88
L28
ICPC
Limited function/disability (L)
3.3
22.5
93
282
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
6.1
22.4
41
65
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.2
22.4
98
307
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
4.6
21.8
55
117
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
0.2
21.8
41
1424
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
4.0
21.5
64
155
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
21.2
274
1434
P99
ICPC
Psychological disorders other
4.3
21.1
58
132
F89
ICD-10 Finland
Unspecified disorder of psychological development
36.7
21.0
27
7
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.5
20.9
78
221
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.1
20.8
92
290
T82
ICPC
Obesity
4.6
20.8
51
106
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
19.7
20.4
31
15
IGY99
NOMESCO Finland
Other psychiatric treatment contact
3.2
20.3
87
269
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
4.7
20.2
49
101
OAB43, ,
SPAT
0.4
20.0
92
1995
Z02.7
ICD-10 Finland
Issue of medical certificate
3.2
19.9
85
262
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.9
19.9
62
155
H50.0
ICD-10 Finland
Convergent concomitant strabismus
5.0
19.8
44
84
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
6.6
19.6
33
48
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
4.1
19.5
56
132
SPAT1389
SPAT
Visit based on need for special support
2.5
19.4
146
608
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
27.4
18.9
26
9
H52.2
ICD-10 Finland
Astigmatism
3.8
18.8
61
157
N06BA09
ATC
atomoxetine; oral
6.7
18.8
31
44
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
18.6
134
546
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.2
18.6
51
116
SPAT1396
SPAT
Meeting with multidisciplinary group of experts
3.9
18.6
57
141
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
3.3
18.5
75
224
N06AB04
ATC
citalopram; systemic
3.0
18.5
91
305
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
6.3
18.5
32
48
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
18.4
170
774
RS220, ,
NOMESCO Finland
5.3
18.4
38
68
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.7
18.1
43
87
H81
ICPC
Excessive ear wax
2.8
18.1
97
341
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.9
18.1
94
325
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
18.0
275
1514
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.8
17.9
101
365
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
7.7
17.9
26
32
ZYC01
NOMESCO Finland
Remote contact by phone
3.0
17.8
86
285
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
5.6
17.7
35
60
C03CA01
ATC
furosemide; systemic
3.6
17.6
60
160
XCK00
NOMESCO Finland
Perimetry
5.4
17.5
36
64
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
49.5
17.4
21
*
N05BA06
ATC
lorazepam; systemic, sublingual
6.1
17.4
31
48
101
Kela drug reimbursment
Anterior pituitary hypofunction
4.8
17.3
40
79
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.7
17.2
57
149
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
6.0
17.0
31
49
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
4.6
17.0
42
88
G47.3
ICD-10 Finland
Sleep apnoea
2.9
16.9
88
304
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
6.6
16.9
28
40
H52.0
ICD-10 Finland
Hypermetropia
3.4
16.9
65
188
SPAT1234
SPAT
Support of social functional capacity
4.6
16.8
41
85
WX002
NOMESCO Finland
Sedation and analgesia
2.5
16.8
112
440
H50.30
ICD-10 Finland
Intermittent esotropy
4.9
16.7
38
74
Q99.8
ICD-10 Finland
Other specified chromosome abnormalities
16.0
16.7
27
16
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.2
16.6
69
209
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
6.3
16.6
29
44
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
6.3
16.6
29
44
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
7.0
16.5
26
35
SPAT1395
SPAT
Health check-up of persons outside student and working life
6.5
16.5
28
41
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
3.8
16.3
51
128
IGP01
NOMESCO Finland
Psychiatric family contact
3.3
16.3
66
197
H53.0
ICD-10 Finland
Amblyopia ex anopsia
4.3
16.3
44
99
N03AX18
ATC
lacosamide; systemic
12.5
16.2
29
22
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
5.7
16.0
31
52
SCA02
NOMESCO Finland
Preventive oral health care
1.8
15.9
335
2033
A06AD11
ATC
lactulose; oral
3.1
15.9
72
230
N29
ICPC
Neurological sympt/complt other
6.4
15.8
27
40
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.1
15.8
71
226
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
15.6
166
797
WZB00, ,
SPAT
0.3
15.6
42
1211
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.5
15.5
56
155
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.3
15.5
130
566
N05AD01
ATC
haloperidol; systemic
7.5
15.5
23
29
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
17.5
15.4
24
13
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.9
15.3
287
1676
RT190, ,
NOMESCO Finland
16.2
15.0
24
14
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
3.7
14.8
49
128
F93.89
ICD-10 Finland
Other childhood emotional disorders
3.5
14.7
52
142
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
2.9
14.7
71
235
DFF00
NOMESCO Finland
Pure tone audiometry
3.1
14.7
63
195
H50.1
ICD-10 Finland
Divergent concomitant strabismus
7.0
14.6
23
31
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
14.6
195
1016
N03AX22
ATC
perampanel; oral
22.0
14.5
21
9
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.9
14.4
70
233
UDC00
NOMESCO Finland
Ear microscopy
2.5
14.1
97
385
EBA05
NOMESCO Finland
Complicated extraction of tooth
2.1
14.1
146
692
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.9
14.1
42
102
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.5
14.0
95
375
F81.0
ICD-10 Finland
Specific reading disorder
13.4
13.9
24
17
R32
ICD-10 Finland
Unspecified urinary incontinence
5.4
13.9
28
49
JDB10
NOMESCO Finland
Percutaneous gastrostomy
6.9
13.8
22
30
WYA20
NOMESCO Finland
Home visit
6.6
13.8
23
33
RT420, ,
NOMESCO Finland
14.5
13.8
23
15
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.7
13.6
80
294
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
5.7
13.6
26
43
F80.0
ICD-10 Finland
Specific speech articulation disorder
6.1
13.5
24
37
RS211, ,
NOMESCO Finland
6.4
13.4
23
34
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
13.6
13.4
23
16
R62.9
ICD-10 Finland
Lack of expected normal physiological development, unspecified
28.2
13.4
18
6
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.4
13.3
49
138
RS314, ,
NOMESCO Finland
22.4
13.2
19
8
3159X
ICD-9 Finland
Specific delays in development, Unspecified delay in development
+∞
13.2
13
*
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
6.0
13.1
24
38
RS140, ,
NOMESCO Finland
10.8
13.1
25
22
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
31.9
13.0
17
5
602
Kela drug reimbursment
Children's severe malnutrition
3.2
13.0
52
154
KAY40, ,
NOMESCO Finland
0.1
12.9
8
484
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
12.9
211
1170
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
12.8
148
730
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
37.5
12.7
16
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
4.3
12.5
33
73
Q93.5
ICD-10 Finland
Other deletions of part of a chromosome
46.9
12.4
15
*
N03AG04
ATC
vigabatrin; oral
10.3
12.4
24
22
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
17.9
12.4
19
10
FM2CE, ,
NOMESCO Finland
2.6
12.4
76
286
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
12.3
168
877
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.7
12.3
67
237
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.6
12.3
41
108
SPAT1216
SPAT
Assessment of functional ability
2.5
12.3
80
310
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
+∞
12.1
12
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.9
12.1
36
87
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.7
12.1
69
250
RL720, ,
NOMESCO Finland
121.7
12.1
13
*
T90
ICPC
Diabetes non-insulin dependent
3.2
12.0
49
147
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
12.0
80
313
AA1AD
NOMESCO Finland
CT of head and brain
2.3
12.0
101
439
N03AX15
ATC
zonisamide; oral
18.8
11.9
18
9
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
4.0
11.9
35
84
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.4
11.9
24
42
F91.9
ICD-10 Finland
Conduct disorder, unspecified
12.4
11.9
21
16
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
12.4
11.9
21
16
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
3.8
11.6
36
90
RS312, ,
NOMESCO Finland
16.9
11.5
18
10
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.9
11.5
54
176
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.1
11.5
124
595
ZXY82
NOMESCO Finland
Nurse in multidisciplinary team
5.4
11.5
23
40
IHZ04, ,
SPAT
4.4
11.5
29
62
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
2.6
11.3
69
259
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
13.8
11.3
19
13
G40.10
ICD-10 Finland
Simple partial seizures
11.0
11.3
21
18
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.0
11.3
50
158
K05.18
ICD-10 Finland
Chronic gingivitis
2.3
11.2
87
365
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.4
11.2
41
115
WX402
NOMESCO Finland
General anaesthesia
1.8
11.2
211
1218
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
5.3
11.2
23
41
RS122, ,
NOMESCO Finland
15.4
11.2
18
11
H47.2
ICD-10 Finland
Optic atrophy
15.4
11.2
18
11
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
11.2
80
324
3153X
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[PUHEEN KEHITYKSEN ERITYISVAIKEUS]
+∞
11.1
11
*
3141A
ICD-9 Finland
Hyperkinetic syndrome of childhood, Hyperkinesis with developmental delay
+∞
11.1
11
*
U04
ICPC
Incontinence urine
4.7
11.1
26
52
G40.89
ICD-10 Finland
Other epilepsy
11.8
11.1
20
16
181
Kela drug reimbursment
Retigabine and vigabatrin
10.4
11.0
21
19
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
11.0
60
213
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.1
10.9
113
533
IGY02, ,
SPAT
4.6
10.9
26
53
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
4.0
10.8
31
73
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
2.6
10.8
65
242
F98.00
ICD-10 Finland
Nonorganic enuresis nocturna
3.3
10.8
41
118
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.5
10.7
87
1559
K59.09
ICD-10 Finland
Constipation, unspecified
2.6
10.7
63
232
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.2
10.7
44
133
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
10.6
148
776
K08.3
ICD-10 Finland
Retained dental root
3.6
10.6
36
96
SPAT1262
SPAT
Handing over of treatment supplies
2.3
10.6
80
332
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
10.5
438
3096
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
5.7
10.5
20
33
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.8
10.5
32
79
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
10.5
130
655
N03AF01
ATC
carbamazepine; oral, rectal
5.3
10.3
21
37
XKD00
NOMESCO Finland
Uroflowmetry
2.8
10.3
53
182
IEP03
NOMESCO Finland
Focused parental counselling
3.3
10.3
39
112
F80
ICD-10 Finland
Specific developmental disorders of speech and language
56.1
10.3
12
*
N06AB03
ATC
fluoxetine; oral
2.2
10.3
92
410
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
4.7
10.3
24
48
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
20.1
10.3
15
7
RF120, ,
NOMESCO Finland
9.0
10.2
21
22
EB1VA, ,
NOMESCO Finland
2.2
10.2
86
374
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.6
10.2
387
2672
SFA30
NOMESCO Finland
Three-surface restoration
1.7
10.2
203
1188
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
10.2
83
356
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
102.7
10.1
11
*
P72
ICPC
Schizophrenia
4.8
10.1
23
45
Z29
ICPC
Social problem NOS
3.2
10.1
41
123
301
Kela drug reimbursment
Growth hormone
4.6
10.0
24
49
SPAT1240
SPAT
Therapeutic discussion
1.9
10.0
143
756
N05AF03
ATC
chlorprothixene; systemic
4.9
9.9
22
42
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.6
9.9
33
87
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.8
9.9
30
74
KAY60, ,
NOMESCO Finland
0.0
9.8
*
256
201
Kela drug reimbursment
Chronic cardiac insufficiency
4.7
9.8
23
46
P07.2
ICD-10 Finland
Extreme immaturity
17.6
9.8
15
8
EJC20
NOMESCO Finland
Operation on frenulum of tongue
3.9
9.8
29
70
UKC02
NOMESCO Finland
Cystoscopy
2.9
9.8
46
150
N06BA12
ATC
lisdexamfetamine; oral
3.3
9.8
37
106
ZXA00
NOMESCO Finland
Right side
2.0
9.8
110
535
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
5.1
9.8
21
39
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
9.9
9.8
19
18
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
9.7
165
920
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
9.7
96
445
SPAT1139
SPAT
Nutrition survey
3.8
9.7
30
75
F90.1
ICD-10 Finland
Hyperkinetic conduct disorder
12.3
9.7
17
13
XF404
NOMESCO Finland
Ambulatory ECG
2.6
9.6
56
205
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
5.2
9.6
20
36
R5110, ,
SPAT
4.4
9.6
24
51
N03AD01
ATC
ethosuximide; oral
13.6
9.5
16
11
N88
ICPC
Epilepsy
7.4
9.5
22
28
TJD20
NOMESCO Finland
Change of gastrostomy tube
5.4
9.5
19
33
RT130, ,
NOMESCO Finland
15.6
9.4
15
9
N03AF03
ATC
rufinamide; oral
18.7
9.4
14
7
A10BA02
ATC
metformin; oral
2.5
9.4
61
236
M41.4
ICD-10 Finland
Neuromuscular scoliosis
11.4
9.4
17
14
G91.1
ICD-10 Finland
Obstructive hydrocephalus
11.4
9.4
17
14
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.3
9.4
76
325
N03AE01
ATC
clonazepam; systemic
3.7
9.3
30
77
Z72.8
ICD-10 Finland
Other problems related to lifestyle
7.2
9.3
22
29
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
7.6
9.3
21
26
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.7
9.3
52
187
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.7
9.2
51
182
K59.0
ICD-10 Finland
Constipation
2.6
9.2
55
204
D12
ICPC
Constipation
3.4
9.2
34
96
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
5.2
9.2
19
34
SPAT1281
SPAT
Other administrative function
2.1
9.2
91
422
EBA30
NOMESCO Finland
Extraction of root of tooth
4.6
9.2
22
45
RL710, ,
NOMESCO Finland
+∞
9.1
9
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.9
9.1
42
136
UJD02
NOMESCO Finland
Gastroscopy
3.8
9.1
28
70
Q93.8
ICD-10 Finland
Other deletions from the autosomes
28.0
9.1
12
*
ZXD20
NOMESCO Finland
Day surgery
2.1
9.0
87
399
OAA43, ,
SPAT
2.4
9.0
66
270
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
9.0
513
3842
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
9.0
98
471
P29
ICPC
Psychological sympt/compl other
1.9
8.9
122
634
E11
ICD-10 Finland
Type 2 diabetes mellitus
4.2
8.9
24
54
ZXD05
NOMESCO Finland
Urgent procedure
1.7
8.9
203
1227
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
11.5
8.9
16
13
ZXY80
NOMESCO Finland
Doctor in multidisciplinary team
4.6
8.8
21
43
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
2.4
8.7
62
250
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
4.4
8.7
22
47
T16
ICD-10 Finland
Foreign body in ear
4.4
8.7
22
47
F40.2
ICD-10 Finland
Specific (isolated) phobias
4.1
8.7
24
55
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
6.8
8.7
21
29
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.3
8.7
65
269
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
5.0
8.6
19
36
Z29.8
ICD-10 Finland
Other specified prophylactic measures
2.4
8.6
58
228
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
14.6
8.6
14
9
N03AX23
ATC
brivaracetam; systemic
10.7
8.6
16
14
EMB30
NOMESCO Finland
Adenotomy
1.8
8.6
155
877
OAA62, ,
SPAT
0.3
8.6
26
718
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.7
8.6
20
40
R33
ICD-10 Finland
Retention of urine
4.5
8.5
21
44
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.8
8.5
147
822
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
3.0
8.5
38
121
ZXA05
NOMESCO Finland
Left side
1.9
8.4
104
522
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
7.4
8.4
19
24
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
10.0
8.4
16
15
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
8.3
51
192
W0A12
NOMESCO Finland
Planned therapy visit for psychiatric disease
8.1
8.3
18
21
RS120, ,
NOMESCO Finland
8.9
8.3
17
18
A41.9
ICD-10 Finland
Sepsis, unspecified
3.1
8.2
35
108
Z71.8
ICD-10 Finland
Other specified counselling
1.6
8.2
293
1969
H61.2
ICD-10 Finland
Impacted cerumen
2.5
8.2
50
188
Z03
ICPC
Housing/neighbourhood problem
15.2
8.2
13
8
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
3.4
8.2
29
80
F60.9
ICD-10 Finland
Personality disorder, unspecified
4.7
8.1
19
38
KAY20, ,
NOMESCO Finland
0.1
8.1
*
286
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
8.1
72
320
ZYC02, ,
SPAT
0.3
8.1
18
588
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.6
8.1
48
178
R11
ICD-10 Finland
Nausea and vomiting
1.9
8.1
108
557
H66.9
ICD-10 Finland
Otitis media, unspecified
1.6
8.1
212
1326
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.1
8.1
79
365
WYA30, ,
SPAT
6.5
8.0
20
29
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
3.7
8.0
25
63
T74.1
ICD-10 Finland
Physical abuse
3.1
8.0
34
105
SPAT1321
SPAT
Health examination of person liable for military service
0.5
8.0
72
1257
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
8.0
134
742
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.4
8.0
55
219
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
11.9
8.0
14
11
N92.2
ICD-10 Finland
Excessive menstruation at puberty
4.8
8.0
18
35
SCA03
NOMESCO Finland
Preventive oral health care, extensive
1.9
7.9
100
507
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.6
7.9
47
175
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.1
7.8
32
97
R13
ICD-10 Finland
Dysphagia
3.1
7.8
32
97
199
Kela drug reimbursment
Rufinamide
16.0
7.7
12
7
SPAT1254
SPAT
Administration of medicine
1.6
7.7
190
1168
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
7.7
78
365
ICB06, ,
NOMESCO Finland
4.0
7.7
22
52
IEP01
NOMESCO Finland
Psychoeducation, family
4.0
7.7
22
52
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.8
7.7
136
765
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
4.5
7.7
19
40
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
4.5
7.7
19
40
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
4.1
7.7
21
48
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
2.9
7.7
36
118
SPAT1303
SPAT
Counselling and guidance related to growth and development
1.9
7.7
95
478
F22.0
ICD-10 Finland
Delusional disorder
9.4
7.6
15
15
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.3
7.6
55
224
T83
ICPC
Overweight
3.7
7.6
24
61
N05BE01
ATC
buspirone; oral
3.7
7.6
24
61
N07BB01
ATC
disulfiram; oral
3.5
7.6
26
70
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.5
7.6
26
70
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.5
7.6
26
70
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
7.5
652
5238
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
3.4
7.5
27
75
Q21.10
ICD-10 Finland
Persistent ostium secundum
3.0
7.5
34
109
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
12.2
7.5
13
10
WX882
NOMESCO Finland
High dependency care
2.0
7.5
82
395
TDA90, ,
SPAT
3.3
7.5
28
80
OAB48, ,
SPAT
0.4
7.4
40
849
RT422, ,
NOMESCO Finland
41.9
7.4
9
*
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
3.6
7.4
24
62
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
7.2
7.4
17
22
N06AX16
ATC
venlafaxine; oral
1.9
7.4
95
483
H13
ICPC
Plugged feeling ear
1.9
7.4
103
538
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.0
7.4
83
403
P98
ICPC
Psychosis NOS/other
6.2
7.4
19
29
N05BA04
ATC
oxazepam; oral
1.8
7.4
128
715
K07.24
ICD-10 Finland
Open bite
2.6
7.4
43
158
W11
ICPC
Contraception oral
0.5
7.4
89
1417
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
7.3
366
2629
SPAT1307
SPAT
Psychosocial counselling and guidance
1.7
7.3
133
754
R56.0
ICD-10 Finland
Febrile convulsions
2.7
7.3
38
132
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
4.1
7.2
20
46
G03DC03
ATC
lynestrenol; oral
4.1
7.2
20
46
ZXY60
NOMESCO Finland
2-person team, nurses
4.4
7.2
18
38
C03DA01
ATC
spironolactone; oral
2.8
7.2
36
122
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.4
7.2
49
194
C01AA05
ATC
digoxin; systemic
11.0
7.2
13
11
H02AB09
ATC
hydrocortisone; systemic
2.3
7.2
52
212
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
7.2
47
183
SPAT1097
SPAT
Recording of ECG
2.5
7.2
44
166
R27.0
ICD-10 Finland
Ataxia, unspecified
74.5
7.2
8
*
F91.3
ICD-10 Finland
Oppositional defiant disorder
9.4
7.1
14
14
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.5
7.1
24
64
IEY01
NOMESCO Finland
Psychoeducation, individual
3.9
7.1
21
51
F98.9
ICD-10 Finland
Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
5.8
7.1
19
31
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
7.1
78
377
S18
ICPC
Laceration/cut
1.5
7.0
284
1949
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
7.0
88
445
E66.8
ICD-10 Finland
Other obesity
2.9
6.9
33
109
P94.2
ICD-10 Finland
Congenital hypotonia
14.7
6.9
11
7
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
5.6
6.9
19
32
K02.1
ICD-10 Finland
Caries of dentine
1.5
6.9
566
4455
E23.00
ICD-10 Finland
Panhypopituitarism
18.6
6.8
10
5
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
18.6
6.8
10
5
N04AA02
ATC
biperiden; systemic
5.8
6.8
18
29
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.5
6.8
41
154
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
3.3
6.8
25
71
ZXA10
NOMESCO Finland
Bilateral
1.7
6.8
133
770
R02
ICPC
Shortness of breath/dyspnoea
1.9
6.7
85
430
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
11.2
6.7
12
10
SPAT1167
SPAT
Insertion of urinary catheter
11.2
6.7
12
10
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
6.7
72
344
SPAT1312
SPAT
General health counselling
1.5
6.7
377
2757
Z61.8
ICD-10 Finland
Other negative life events in childhood
6.1
6.7
17
26
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.7
217
1420
Z50.1
ICD-10 Finland
Other physical therapy
3.4
6.7
24
67
Z07
ICPC
Education problem
2.7
6.7
34
117
EBA00
NOMESCO Finland
Extraction of tooth
1.4
6.6
396
2926
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.0
6.6
19
45
WW200, ,
SPAT
1.7
6.6
125
715
A08.0
ICD-10 Finland
Rotaviral enteritis
3.3
6.6
25
72
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
4.3
6.6
17
37
SPAT1154
SPAT
Insertion or removal of subcutaneous medicine capsule
3.2
6.6
26
77
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
6.6
42
162
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.6
6.5
158
964
SPAT1210
SPAT
Application of cast or individual aid
2.6
6.5
38
140
Q02
ICD-10 Finland
Microcephaly
37.2
6.5
8
*
N05AL05
ATC
amisulpride; oral
37.2
6.5
8
*
R2210
NOMESCO Finland
Guidance to educational rehabilitation
37.2
6.5
8
*
R49.2
ICD-10 Finland
Hypernasality and hyponasality
37.2
6.5
8
*
N05AX13
ATC
paliperidone; systemic
5.9
6.5
17
27
S29
ICPC
Skin symptom/complaint other
1.6
6.5
161
989
A11CC03
ATC
alfacalcidol; systemic
3.2
6.5
25
73
Q75.3
ICD-10 Finland
Macrocephaly
15.5
6.5
10
6
RS231, ,
NOMESCO Finland
15.5
6.5
10
6
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
2.9
6.4
29
93
R4190
NOMESCO Finland
Nutritional therapy
1.8
6.4
103
562
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
6.4
59
266
RS311, ,
NOMESCO Finland
8.7
6.4
13
14
Z13.4
ICD-10 Finland
Special screening examination for certain developmental disorders in childhood
21.0
6.4
9
*
Q87.14
ICD-10 Finland
Noonan's syndrome
21.0
6.4
9
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
6.4
76
377
Z01.2
ICD-10 Finland
Dental examination
1.4
6.3
531
4162
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
5.3
6.3
18
32
SPAT1301
SPAT
No procedures
1.5
6.3
251
1712
OAB95, ,
SPAT
0.3
6.3
13
443
C07AB02
ATC
metoprolol; systemic
2.5
6.3
40
154
C09AA02
ATC
enalapril; systemic
2.7
6.3
32
110
F79
ICD-10 Finland
Unspecified mental retardation
11.4
6.3
11
9
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
6.0
6.2
16
25
Q87.19
ICD-10 Finland
Congenital malformation syndromes predominantly associated with short stature
64.9
6.2
7
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.5
6.2
37
138
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.4
6.2
314
2243
SPAT1360
SPAT
Extensive global examination
2.3
6.2
46
190
E22.80
ICD-10 Finland
Central precocious puberty
9.3
6.2
12
12
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.0
6.2
27
85
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.4
6.2
41
161
R2110
NOMESCO Finland
Giving the first information
2.4
6.2
41
161
U07
ICPC
Urine symptom/complaint other
2.4
6.2
42
167
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
2.1
6.2
57
258
IEP02
NOMESCO Finland
Child-centred family therapy
2.5
6.1
37
139
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.9
6.1
72
356
ZXY58
NOMESCO Finland
2-person team, nurse-occupational therapist
13.3
6.1
10
7
Q04.8
ICD-10 Finland
Other specified congenital malformations of brain
13.3
6.1
10
7
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.5
6.1
215
1429
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
2.9
6.1
28
91
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
3.5
6.1
21
57
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.1
312
2233
F80.3
ICD-10 Finland
Acquired aphasia with epilepsy [Landau-Kleffner]
+∞
6.1
6
*
Q87.31
ICD-10 Finland
Syndrome Sotos
+∞
6.1
6
*
N28
ICPC
Limited function/disability (N)
5.8
6.1
16
26
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
3.8
6.0
18
44
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
5.3
6.0
17
30
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
5.3
6.0
17
30
XX4BW, ,
NOMESCO Finland
5.3
6.0
17
30
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
16.8
6.0
9
5

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
231
937
2.72
33.88
2.9
2.3
262.30
416.18
u/l
0.92
226
906
435
2481
2.20
28.78
15.5
11.4
1.22
1.23
mmol/l
1.32
424
2360
450
2613
2.18
28.31
13.4
10.8
1.22
1.22
mmol/l
0.45
418
2393
401
2229
2.19
28.13
3.8
3.2
67.11
68.22
nmol/l
0.36
388
2114
533
3431
2.06
24.08
6.9
5.9
120.23
106.63
u/l
3.22
499
3236
264
1311
2.22
23.76
2.5
2.9
2.38
2.39
mmol/l
0.57
245
1194
757
5645
2.50
22.70
17.8
10.8
139.68
139.47
mmol/l
1.81
739
5457
756
5656
2.46
22.09
17.6
10.8
3.95
3.93
mmol/l
1.37
734
5440
134
507
2.69
21.82
13.0
14.3
1.61
1.36
mmol/l
1.55
127
496
709
5210
2.21
20.77
4.7
3.8
2.02
1.89
mu/l
2.46
669
4905
315
1785
1.97
19.20
6.4
7.8
38.05
38.35
g/l
0.42
301
1698
259
1378
2.03
18.82
5.9
5.0
1.09
1.07
inr
0.25
79
411
217
1095
2.09
18.11
11.1
10.5
1.30
1.33
mmol/l
0.96
209
1044
629
4541
1.93
17.54
4.2
3.4
14.42
14.52
pmol/l
0.41
587
4120
475
3141
1.84
17.49
8.8
6.7
5.94
6.10
mmol/l
0.95
448
2879
217
1121
2.04
16.86
4.9
4.0
7.38
7.39
ph
0.70
49
192
779
6114
2.31
16.65
10.5
8.1
30.53
27.59
u/l
2.14
760
5910
348
2126
1.83
16.24
9.2
7.1
19.73
19.57
umol/l
0.02
324
1958
29
45
6.11
16.20
2.6
2.6
—
—
—
0
0
259
1455
1.90
15.63
4.8
4.6
8.40
8.72
mmol/l
0.38
242
1363
209
1092
2.00
15.61
14.5
8.9
7.40
7.40
ph
0.27
13
41
46
111
3.98
15.53
5.0
6.0
—
—
—
0
0
384
2478
1.75
14.45
2.7
2.1
—
—
—
0
0
555
3986
1.74
14.11
3.8
2.3
5.66
5.40
mmol/l
3.47
516
3669
199
1056
1.95
14.06
14.0
10.1
—
—
—
0
0
156
769
2.06
13.53
12.7
10.9
0.81
0.81
mmol/l
0.18
151
739
214
1179
1.89
13.45
7.9
9.3
1.19
1.21
mmol/l
0.03
169
948
148
718
2.08
13.39
3.2
2.2
—
—
—
0
0
112
486
2.29
13.38
8.9
5.5
885.00
1051.99
ng/l
0.17
93
384
211
1167
1.87
13.06
4.2
3.0
562.96
592.59
mosm/kgh2o
0.82
184
1011
57
181
3.04
12.71
7.5
11.4
22.88
23.37
mmol/l
0.63
57
172
24
21
10.81
12.66
1.1
1.4
—
—
—
0
0
282
1728
1.74
12.30
4.4
4.4
35.72
32.94
u/l
0.35
272
1635
496
3530
1.66
12.28
4.4
3.1
36.51
36.29
mmol/mol
0.17
462
3349
43
118
3.48
12.11
6.4
6.1
7.40
7.40
ph
0.09
38
108
210
1188
1.82
11.99
4.4
3.1
9.23
6.42
e6/l
1.16
183
1052
342
2223
1.68
11.93
6.5
4.6
114.41
59.26
e6/l
0.58
242
1444
115
529
2.15
11.89
14.9
18.3
1.09
1.03
mg/l
0.87
115
522
220
1269
1.79
11.75
3.4
2.3
—
—
—
0
0
295
1850
1.70
11.73
5.6
3.9
24.57
51.75
e6/l
0.79
228
1377
140
700
2.00
11.58
3.0
2.7
325.51
351.49
nmol/l
0.90
132
667
85
352
2.36
11.28
1.5
1.6
1093.16
1081.15
nmol/l
0.04
74
268
65
241
2.61
10.90
3.4
3.3
—
—
—
0
0
43
128
3.21
10.69
2.1
1.4
—
—
—
0
0
271
1713
1.66
10.21
5.6
3.8
0.12
0.23
e6/l
1.90
211
1256
172
968
1.79
9.82
15.3
8.4
—
—
—
0
0
496
3653
1.56
9.66
9.7
8.6
0.04
0.04
e9/l
0.10
428
3050
496
3655
1.56
9.62
9.7
8.6
0.60
0.56
e9/l
2.19
428
3054
271
1735
1.63
9.61
5.5
3.7
—
—
—
0
0
304
2007
1.60
9.48
9.5
8.5
—
—
—
0
0
73
306
2.31
9.43
6.7
8.4
0.33
0.41
g/l
0.37
45
241
36
104
3.29
9.41
6.7
6.7
2.20
1.83
mmol/l
0.33
22
55
250
1578
1.64
9.34
6.6
7.0
88.42
87.45
%
0.26
244
1559
505
3752
1.55
9.32
10.6
9.2
0.21
0.21
e9/l
0.17
439
3202
471
3448
1.55
9.28
11.1
10.0
0.00
0.00
e9/l
0.42
380
2620
173
992
1.76
9.22
15.3
8.1
23.92
24.03
mmol/l
0.28
173
986
74
315
2.27
9.22
17.9
14.2
0.04
0.34
mmol/l
0.25
55
258
132
697
1.88
9.22
1.7
1.3
17.24
18.96
nmol/l
0.79
121
617
9
0
+∞
9.11
4.1
0.0
334.00
—
umol/l
—
9
0
21
27
7.32
9.07
2.2
2.8
21.21
13.82
umol/l
1.31
21
27
167
953
1.76
9.04
3.0
2.1
28.84
31.41
ng/l
0.06
84
332
117
603
1.91
8.79
3.4
4.7
0.22
0.22
g/l
0.17
110
579
115
595
1.90
8.53
3.3
3.9
790.46
108.33
mg/l
0.63
90
463
34
103
3.13
8.26
3.1
3.3
17.70
18.26
%
0.28
20
60
201
1239
1.64
8.11
1.7
1.5
100.18
98.97
pmol/l
0.14
113
649
18
22
7.69
8.10
1.0
1.3
—
—
—
0
0
115
605
1.87
8.10
4.1
4.6
12.05
38.09
mg/mmol
0.54
89
465
62
259
2.30
8.09
3.5
3.8
—
—
—
0
0
462
3448
1.49
7.76
9.8
9.2
—
—
—
0
0
31
748
0.36
7.74
1.2
1.2
—
—
—
0
0
45
167
2.57
7.58
1.6
2.0
12.87
6.68
ug/l
0.63
38
140
178
1086
1.64
7.43
4.6
3.3
0.92
0.76
e6/l
0.39
113
591
221
1425
1.57
7.33
4.0
3.1
—
—
—
0
0
35
116
2.86
7.31
6.5
7.8
—
—
—
0
0
32
101
3.00
7.28
13.7
5.2
—
—
—
0
0
520
4003
1.47
7.27
15.1
10.5
3.84
3.58
e9/l
1.83
447
3339
211
1352
1.58
7.17
4.1
3.3
0.03
0.00
estimate
0.44
74
495
86
429
1.94
7.11
4.3
3.0
—
—
—
0
0
196
1238
1.59
7.07
3.0
2.8
52.92
56.37
u/l
0.62
185
1149
177
1091
1.62
7.07
4.7
3.5
5.15
2.05
e6/l
2.19
114
601
96
498
1.87
7.06
2.5
2.1
6.13
5.79
u/l
0.18
69
329
95
492
1.88
7.02
1.7
1.4
433.95
15056633.25
pmol/l
0.50
86
445
498
3820
1.46
6.96
9.8
8.4
2.35
2.29
e9/l
0.53
434
3300
99
521
1.85
6.96
1.5
1.8
—
—
—
0
0
11
437
0.22
6.86
1.2
1.2
—
—
—
0
0
56
244
2.19
6.64
5.5
13.5
0.72
0.66
%
0.46
56
244
44
173
2.42
6.60
3.0
3.9
—
—
—
0
0
170
1058
1.60
6.49
4.0
4.1
—
—
—
0
0
33
115
2.71
6.32
3.8
2.0
—
—
—
0
0
453
3463
1.42
6.14
9.2
8.7
0.57
0.63
%
1.27
437
3316
204
1339
1.53
6.13
3.3
2.8
—
—
—
0
0
133
792
1.65
6.05
2.2
1.6
—
—
—
0
0
49
211
2.21
6.00
2.0
1.8
—
—
—
0
0
74
378
1.88
5.72
5.9
5.7
0.14
0.05
%
0.52
28
129
323
2352
1.42
5.63
4.1
3.0
6.48
6.10
ph
1.46
24
252
463
3589
1.39
5.59
9.3
8.8
8.25
8.24
%
0.04
447
3435
235
1616
1.46
5.57
3.4
2.9
—
—
—
0
0
459
3556
1.39
5.54
9.2
8.6
2.95
3.15
%
0.90
444
3400
94
522
1.74
5.54
2.5
2.2
8.57
11.29
nmol/l
2.43
83
471
32
118
2.56
5.52
3.7
8.9
—
—
—
0
0
192
1270
1.50
5.52
4.0
2.9
1.02
1.02
kg/l
0.15
21
204
49
219
2.13
5.49
25.0
15.9
93.78
95.55
%
0.74
49
219
770
6562
1.58
5.40
13.5
7.5
—
—
—
0
0
75
401
1.79
5.04
6.1
5.5
1.07
0.66
%
0.43
30
151
123
1645
0.64
4.95
1.9
1.8
—
—
—
0
0
120
736
1.58
4.83
6.7
6.2
1.45
1.43
%
0.09
115
705
525
4211
1.36
4.82
3.8
2.6
2.67
2.71
mmol/l
0.61
496
3990
43
194
2.10
4.74
25.8
17.6
—
—
—
0
0
70
374
1.79
4.72
6.0
5.7
0.00
0.07
%
1.92
23
123
84
476
1.69
4.62
1.8
2.2
2.38
2.40
mmol/l
0.69
68
401
520
4180
1.35
4.62
3.6
2.6
1.24
1.39
mmol/l
18.04
489
3978
210
2504
0.71
4.60
2.4
2.2
—
—
—
0
0
527
4248
1.35
4.58
3.8
2.7
4.27
4.43
mmol/l
4.16
502
4064
19
59
3.02
4.51
3.2
2.8
37632.74
41096.61
ug/l
0.37
19
59
154
1018
1.48
4.39
1.7
1.8
1.50
1.31
mmol/l
1.10
139
936
452
3583
1.33
4.28
6.2
3.6
242.64
159.89
e6/l
0.20
11
38
68
372
1.74
4.25
4.7
4.9
0.81
0.49
%
0.46
27
136
117
735
1.54
4.24
3.3
3.0
2.61
2.56
g/l
0.34
112
702
61
324
1.79
4.22
1.9
1.3
—
—
—
0
0
77
438
1.68
4.19
2.0
1.7
434.55
318.73
mu/l
1.92
69
393
29
119
2.29
4.05
3.3
7.4
—
—
—
0
0
354
2728
1.33
4.00
4.4
3.2
0.05
0.00
estimate
0.49
77
509
123
792
1.50
3.98
3.3
3.0
13.22
14.37
umol/l
0.97
117
765
79
459
1.65
3.98
2.5
2.0
6.62
7.67
iu/l
0.47
57
308
355
2748
1.32
3.85
4.3
3.2
0.00
0.00
estimate
-0.00
72
502
19
65
2.74
3.84
1.2
1.3
1.61
1.25
promille
—
10
51
29
122
2.23
3.84
6.0
8.2
61.77
530.77
g/mol
0.65
24
115
723
6191
1.40
3.83
21.7
13.6
14.06
13.39
%
3.78
709
6077
118
1517
0.68
3.83
2.5
1.8
—
—
—
0
0
469
3777
1.31
3.79
9.3
8.4
33.56
34.71
%
1.27
455
3634
18
61
2.76
3.70
1.2
1.1
269.44
291.16
mg/l
0.45
18
55
490
3988
1.29
3.57
3.6
2.5
1.30
1.14
mmol/l
3.83
463
3795
459
3706
1.29
3.54
9.1
8.2
51.43
50.27
%
1.12
444
3564
349
2724
1.30
3.47
5.8
4.6
0.00
0.00
estimate
-0.00
76
518
150
1033
1.41
3.42
4.4
3.8
1.23
1.45
mg/l
0.30
118
693
109
709
1.48
3.37
4.9
6.3
4.99
6.84
umol/l
1.45
94
584
164
1951
0.73
3.37
1.8
1.7
—
—
—
0
0
848
7535
1.68
3.28
25.8
14.9
40.23
41.07
%
0.71
816
7237
849
7547
1.68
3.26
24.5
14.2
29.02
29.22
pg
2.08
838
7446
849
7548
1.68
3.25
24.5
14.2
86.60
86.76
fl
0.41
838
7445
848
7537
1.67
3.25
24.7
14.4
271.26
265.05
e9/l
1.87
819
7215
20
77
2.43
3.24
3.9
5.6
—
—
—
0
0
849
7549
1.68
3.23
24.6
14.3
4.70
4.68
e12/l
0.29
815
7213
849
7551
1.67
3.20
24.8
14.3
7.20
6.86
e9/l
2.66
818
7221
7
10
6.50
3.17
4.4
12.7
—
—
—
0
0
849
7554
1.66
3.15
25.9
14.5
135.97
136.41
g/l
0.37
840
7449
21
85
2.31
3.07
3.7
5.2
—
—
—
0
0
202
1492
1.32
2.95
2.4
3.2
3.08
2.60
mg/l
2.67
178
1338
29
138
1.97
2.87
3.9
4.4
48.52
50.77
%
0.47
29
138
12
35
3.19
2.83
3.9
3.5
184.40
211.41
umol/l
—
5
17
13
287
0.41
2.75
1.3
1.4
—
—
—
0
0
75
473
1.51
2.72
3.9
3.5
—
—
—
0
0
443
3636
1.25
2.71
4.7
3.6
36.93
28.42
u/l
3.63
428
3497
80
513
1.48
2.68
5.3
4.6
69.43
62.71
e9/l
0.82
58
311
29
142
1.91
2.66
1.1
1.4
394.22
382.15
ug/g
0.12
18
67
16
64
2.33
2.43
1.1
1.6
—
—
—
0
0
76
493
1.46
2.43
2.2
2.6
27.97
31.69
u/l
0.59
65
402
94
635
1.41
2.42
2.0
2.0
—
—
—
0
0
5
7
6.62
2.41
15.2
4.7
48.14
46.14
umol/l
—
5
7
462
3849
1.22
2.33
5.6
3.9
—
—
—
0
0
37
205
1.69
2.32
2.2
1.8
—
—
—
0
0
18
78
2.15
2.30
7.3
8.3
—
—
—
0
0
17
73
2.17
2.22
2.2
2.7
4.73
3.24
ug/l
0.13
17
63
17
73
2.17
2.22
4.4
4.0
12.64
2.27
%
—
7
27
10
32
2.91
2.21
2.7
2.3
—
—
—
0
0
16
68
2.19
2.15
1.6
1.5
—
—
—
0
0
38
545
0.63
2.11
1.5
1.4
—
—
—
0
0
740
6510
1.28
2.10
15.3
9.8
22.18
22.44
mg/l
0.07
570
4497
8
23
3.23
2.08
3.3
2.9
—
—
—
0
0
21
101
1.94
2.07
3.8
2.2
1.60
2.13
mmol/l
0.54
14
81
26
137
1.77
1.96
3.2
4.2
3.58
3.26
e9/l
0.28
26
137
38
223
1.60
1.95
1.8
4.2
7.97
6.94
e6/l
0.05
32
154
38
223
1.60
1.95
1.9
4.2
140.79
370.66
e6/l
0.56
33
159
9
30
2.79
1.95
1.0
1.0
—
19.31
—
0
6
6
15
3.71
1.89
3.5
3.3
—
—
—
0
0
11
42
2.44
1.87
2.1
2.5
32.18
31.88
pg
0.07
11
42
12
48
2.33
1.86
1.0
1.0
—
—
—
0
0
11
40
2.56
1.85
2.6
7.7
—
—
—
0
0
20
99
1.88
1.84
1.2
1.0
—
—
—
0
0
12
50
2.23
1.71
1.0
1.1
—
—
—
0
0
6
17
3.27
1.69
1.7
1.8
—
—
—
0
0
25
137
1.70
1.68
2.3
2.8
136.64
138.39
g/l
0.14
25
109
14
63
2.07
1.67
1.8
1.5
222.57
507.43
pmol/l
1.02
14
58
32
188
1.59
1.67
1.4
1.8
—
—
—
0
0
39
524
0.67
1.64
1.1
1.2
2.69
2.95
u/ml
0.08
23
384
21
111
1.76
1.60
1.0
1.1
1.46
1.38
g/l
0.51
21
103
21
111
1.76
1.60
2.3
1.6
—
—
—
0
0
28
162
1.61
1.56
8.6
18.2
—
—
—
0
0
8
30
2.47
1.55
1.6
1.9
—
—
—
0
0
8
30
2.47
1.55
1.3
1.5
—
—
—
0
0
14
66
1.97
1.50
1.6
1.7
68.46
247.80
mu/l
0.66
14
60
7
25
2.60
1.50
1.6
1.9
3.91
3.88
mmol/l
—
7
25
5
14
3.31
1.49
3.0
2.0
—
—
—
0
0
25
361
0.63
1.49
1.1
1.1
—
—
—
0
0
23
128
1.68
1.49
1.6
1.1
—
—
—
0
0
30
179
1.57
1.49
1.3
1.3
—
—
—
0
0
13
60
2.01
1.47
1.2
1.1
—
—
—
0
0
19
292
0.59
1.46
1.3
1.5
—
—
—
0
0
19
292
0.59
1.46
1.4
1.5
—
—
—
0
0
16
257
0.57
1.45
1.2
1.1
—
—
—
0
0
17
87
1.82
1.45
3.1
3.9
2.24
0.77
%
0.77
17
76
6
20
2.78
1.44
1.0
1.2
—
—
—
0
0
468
4010
1.16
1.44
4.3
3.9
7.84
7.06
mm/h
1.26
438
3726
309
2565
1.17
1.44
1.6
1.8
2.37
3.08
u/ml
0.20
68
499
26
153
1.59
1.38
3.5
3.0
274.50
360.30
e6/l
0.49
20
99
6
21
2.65
1.37
1.7
1.2
67.83
71.67
umol/l
—
6
21
16
252
0.58
1.37
1.6
1.1
—
—
—
0
0
20
110
1.69
1.36
11.3
23.5
11.40
11.64
%
0.17
20
110
172
1836
0.83
1.36
1.9
1.7
—
—
—
0
0
38
245
1.45
1.34
1.7
1.7
0.82
0.94
ug/l
0.64
32
225
14
69
1.89
1.34
1.4
1.8
—
—
—
0
0
16
250
0.58
1.33
1.6
1.1
—
—
—
0
0
70
821
0.77
1.31
2.0
1.6
—
—
—
0
0
47
579
0.74
1.25
1.1
1.3
4.81
2.84
u/ml
0.29
27
409
29
180
1.50
1.24
3.0
2.1
—
—
—
0
0
6
23
2.42
1.24
1.7
2.0
—
—
—
0
0
12
58
1.92
1.22
2.8
2.1
—
—
—
0
0
93
700
1.25
1.22
5.7
4.2
327.64
2265.16
umol/l
1.31
86
667
21
299
0.64
1.21
1.3
1.5
—
—
—
0
0
43
533
0.73
1.20
1.1
1.2
0.26
1.11
u/ml
2.58
22
373
6
24
2.32
1.18
1.7
2.0
105.17
106.54
mmol/l
—
6
24
19
108
1.64
1.17
2.9
4.9
25.42
24.45
umol/l
0.22
19
108
278
2322
1.15
1.17
3.5
3.0
—
—
—
0
0
94
715
1.24
1.13
4.7
3.2
3058.74
1151.69
ng/l
0.49
54
371
85
644
1.24
1.07
3.1
2.6
13926.92
4694.82
u/l
0.51
21
243
14
75
1.73
1.07
1.9
2.8
36.00
32.93
mmol/l
0.20
14
75
136
1449
0.84
1.06
1.6
1.6
—
—
—
0
0
45
541
0.76
1.04
1.1
1.2
4.49
6.97
u/ml
0.50
26
407
78
590
1.24
1.01
1.3
1.3
71.22
118.42
iu/ml
0.56
21
197
101
791
1.20
0.94
4.0
2.2
—
—
—
0
0
31
209
1.38
0.92
1.9
4.4
—
—
—
0
0
13
72
1.68
0.91
2.5
2.3
—
—
—
0
0
10
52
1.78
0.85
4.2
3.4
—
—
—
0
0
23
149
1.44
0.85
1.9
1.9
8.23
4.67
iu/l
—
8
54
86
672
1.20
0.84
4.4
3.0
—
—
—
0
0
27
181
1.39
0.84
1.3
1.1
93.17
231.85
iu/ml
—
6
56
6
30
1.85
0.80
4.0
6.0
87.83
214.10
ug/l
—
6
30
280
2399
1.11
0.76
1.7
1.6
1.72
1.70
g/l
0.09
152
1304
46
341
1.26
0.75
1.6
1.2
—
—
—
0
0
7
35
1.85
0.74
1.6
2.5
8.71
204.66
ug/min
—
7
29
5
23
2.01
0.73
1.8
1.3
—
—
—
0
0
26
313
0.76
0.66
1.1
1.1
—
9.04
—
0
14
7
40
1.62
0.66
3.3
3.9
45.21
49.30
%
—
7
33
7
40
1.62
0.66
1.3
1.2
—
—
nmol/l
—
0
0
7
40
1.62
0.66
1.3
2.1
—
—
—
0
0
60
466
1.20
0.66
1.3
1.3
—
—
—
0
0
5
26
1.78
0.65
1.2
1.2
—
—
—
0
0
7
41
1.58
0.64
2.0
1.1
—
—
—
0
0
7
41
1.58
0.64
2.0
1.1
—
—
—
0
0
7
41
1.58
0.64
2.0
1.1
—
—
—
0
0
87
700
1.16
0.64
1.4
1.4
135.60
359.64
u/ml
3.52
81
661
20
248
0.74
0.63
1.5
1.3
—
—
—
0
0
10
140
0.66
0.60
2.1
1.4
—
—
—
0
0
0
19
0.00
0.60
0.0
2.8
—
—
—
0
0
130
1327
0.89
0.60
2.7
3.3
93.27
112.77
ug/g
0.34
99
1062
29
211
1.28
0.57
1.0
1.0
3.58
3.31
kpa
0.39
23
182
6
33
1.68
0.57
1.0
1.2
—
—
—
0
0
6
35
1.59
0.54
1.5
1.3
—
—
—
0
0
29
214
1.26
0.53
1.0
1.0
—
—
—
0
0
29
214
1.26
0.53
1.0
1.0
6.70
7.36
kpa
1.04
23
184
29
214
1.26
0.53
1.0
1.0
-0.44
-2.86
mmol/l
—
7
44
70
737
0.87
0.52
1.7
1.4
—
—
—
0
0
6
37
1.50
0.51
1.0
1.1
—
—
—
0
0
5
77
0.60
0.46
5.6
3.1
7.00
31.33
u/ml
—
5
65
62
650
0.87
0.45
1.3
1.2
1.20
7.56
u/ml
2.70
22
219
67
698
0.88
0.45
1.3
1.2
36.07
14.67
iu/ml
—
10
160
37
287
1.20
0.45
1.4
1.5
—
—
—
0
0
19
136
1.30
0.44
2.7
2.3
—
—
—
0
0
25
283
0.81
0.43
5.4
4.3
12.52
8.88
umol/l
0.63
20
238
8
51
1.45
0.43
1.4
1.2
—
—
—
0
0
8
53
1.40
0.42
2.1
3.5
19.52
32.70
ug/l
—
8
48
0
14
0.00
0.41
0.0
8.1
—
—
—
0
0
0
14
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
21
156
1.25
0.38
2.1
5.4
—
—
—
0
0
17
198
0.79
0.38
1.0
1.1
6.44
6.27
u/ml
—
5
74
18
207
0.80
0.37
1.6
1.7
—
—
—
0
0
13
156
0.77
0.37
1.1
1.1
—
—
—
0
0
31
336
0.85
0.36
1.1
1.1
13.22
7.67
u/ml
0.57
16
215
5
70
0.66
0.36
1.0
1.2
—
—
—
0
0
9
114
0.73
0.35
1.1
1.4
—
242.86
—
0
7
9
114
0.73
0.35
1.1
1.4
—
198.85
—
0
26
41
432
0.87
0.34
1.2
1.2
—
—
—
0
0
54
445
1.13
0.33
1.9
2.0
—
—
—
0
0
18
134
1.25
0.33
1.4
1.1
—
—
—
0
0
45
368
1.14
0.32
3.4
2.0
4.73
4.67
e9/l
0.03
39
339
15
110
1.26
0.31
1.3
1.4
4.22
5.31
u/ml
—
9
54
15
110
1.26
0.31
1.2
1.3
—
—
—
0
0
7
50
1.29
0.30
1.1
1.7
—
—
—
0
0
32
257
1.16
0.29
1.8
1.5
0.19
0.21
g/l
0.43
32
245
27
214
1.17
0.29
1.4
1.1
—
—
—
0
0
35
284
1.14
0.28
2.4
2.2
—
—
—
0
0
37
385
0.88
0.28
1.5
1.3
89.00
252.85
miu/ml
—
5
188
28
297
0.87
0.27
1.1
1.1
2.29
0.35
u/ml
0.39
11
144
8
60
1.23
0.27
1.1
1.1
—
—
—
0
0
109
946
1.07
0.26
3.4
2.1
—
—
—
0
0
18
139
1.20
0.25
1.1
1.1
—
—
—
0
0
9
69
1.21
0.25
1.7
1.7
—
—
—
0
0
6
78
0.71
0.24
1.8
1.6
—
—
—
0
0
22
175
1.16
0.23
1.2
1.2
—
—
—
0
0
5
36
1.28
0.23
1.4
1.3
—
—
—
0
0
7
85
0.76
0.22
1.0
1.3
—
40.40
—
0
5
5
37
1.25
0.22
1.4
1.3
—
—
—
0
0
22
176
1.16
0.22
1.2
1.1
3.44
7.89
iu/ml
—
7
24
17
133
1.18
0.21
2.1
3.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
80.63
—
0
11
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
3.1
—
12.37
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
6
45
1.23
0.20
1.2
1.2
134.20
232.96
iu/ml
—
6
45
164
1456
1.05
0.20
3.7
2.7
—
—
—
0
0
110
1066
0.95
0.19
1.2
1.2
—
—
—
0
0
37
373
0.91
0.18
1.4
1.2
—
—
—
0
0
41
348
1.09
0.18
2.5
2.0
—
—
—
0
0
13
101
1.19
0.18
1.0
1.1
—
—
—
0
0
93
818
1.06
0.17
1.5
1.5
527.27
510.00
titre
0.02
11
116
8
63
1.17
0.16
1.4
1.2
—
—
—
0
0
8
66
1.12
0.16
1.4
1.1
—
—
—
0
0
37
315
1.09
0.15
1.7
1.6
—
—
—
0
0
17
138
1.14
0.15
1.1
1.1
—
—
—
0
0
7
80
0.81
0.14
1.4
1.1
—
—
—
0
0
26
218
1.10
0.14
1.2
1.2
—
—
—
0
0
338
3068
1.03
0.13
3.3
3.1
63.34
60.41
ug/l
0.22
316
2907
135
1213
1.03
0.11
1.9
1.6
—
—
—
0
0
5
44
1.05
0.09
1.2
1.0
—
—
—
0
0
5
45
1.03
0.09
1.0
1.1
1508.60
1594.09
miu/ml
—
5
45
237
2222
0.98
0.08
1.6
1.7
—
—
—
0
0
7
63
1.03
0.08
1.6
1.2
—
—
—
0
0
7
63
1.03
0.08
1.3
1.2
—
—
—
0
0
6
67
0.83
0.07
1.3
1.1
—
—
—
0
0
6
67
0.83
0.07
1.0
1.0
—
—
—
0
0
32
311
0.95
0.07
1.1
1.1
9.45
10.53
u/ml
0.08
15
189
13
109
1.10
0.07
2.9
3.4
1.89
2.05
ug/l
—
7
60
9
82
1.01
0.07
1.4
2.3
11.81
8.93
mg/l
—
9
77
107
1008
0.98
0.06
3.7
2.0
—
—
—
0
0
14
140
0.92
0.06
1.6
2.2
28.71
37.32
u/ml
0.31
14
135
15
148
0.93
0.04
1.2
1.4
89.41
13.51
u/ml
—
9
120
34
303
1.04
0.04
1.1
1.1
—
—
—
0
0
25
222
1.04
0.03
1.1
1.4
3.13
3.86
u/ml
0.09
19
158
20
177
1.04
0.02
2.1
1.4
—
—
—
0
0
12
117
0.95
0.01
3.3
2.6
11.67
24.18
mg/l
—
7
74
47
441
0.98
0.01
2.3
1.8
195.27
166.07
u/ml
0.42
30
219
13
126
0.95
0.01
2.2
4.2
—
—
—
0
0
15
133
1.04
0.00
1.3
1.3
—
—
—
0
0
24
227
0.98
0.00
1.8
1.7
29.38
35.71
nmol/l
1.14
24
221
42
392
0.99
0.00
1.5
1.5
—
—
—
0
0
17
154
1.02
0.00
2.7
2.3
—
—
—
0
0
11
106
0.96
0.00
1.2
1.2
—
—
—
0
0
20
186
0.99
0.00
1.3
1.7
—
12.06
—
0
5
110
1015
1.00
0.00
3.7
2.1
—
—
—
0
0
15
141
0.98
0.00
2.5
2.6
—
—
—
0
0
111
1022
1.00
0.00
3.7
2.1
—
—
—
0
0
111
1024
1.00
0.00
3.8
2.1
—
—
—
0
0
6
56
0.99
0.00
1.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
2.64
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
4.00
—
0
5
5
49
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
5
50
0.92
-0.00
2.0
3.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
28.40
—
0
8
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
58
0.95
-0.00
2.0
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
49
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
62.02
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
18.14
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.88
-0.00
1.2
1.8
7633.67
12362.07
e6/l
—
6
46

Mortality – FinRegistry

Association

Association between endpoint F5_MIXEDDEV and mortality.

Females

Parameter HR [95% CI] p-value
F5_MIXEDDEV 3.661 [2.58, 5.2] < 0.001
Birth year 0.99 [0.98, 1.0] 0.032

During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 8685 females with F5_MIXEDDEV died.

Males

Parameter HR [95% CI] p-value
F5_MIXEDDEV 2.156 [1.77, 2.62] < 0.001
Birth year 0.987 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 146 out of 19887 males with F5_MIXEDDEV died.

Mortality risk

Mortality risk for people of age

years, who have F5_MIXEDDEV.

N-year risk Females Males
1 0.259% 0.317%
5 1.439% 2.249%
10 4.139% 6.384%
15 8.235% 11.432%
20 14.601% 18.666%

Relationships between endpoints

Index endpoint: F5_MIXEDDEV – Mixed specific developmental disorders

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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