tongue neoplasm: A neoplasm (disease) that involves the tongue.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
986 |
4. Check minimum number of eventsNone |
986 |
5. Include endpointsNone |
986 |
6. Filter based on genotype QC (FinnGen only) |
986 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10
- Name in latin
- Neoplasma benignum linguae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Tongue
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Tongue
- Benign neoplasm of mouth and pharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6857 | 3760 | 3044 |
| Only index persons | 6202 | 3455 | 2747 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.09 |
| Only index persons | 0.12 | 0.13 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 57.60 | 58.88 | 56.04 |
| Only index persons | 57.19 | 58.39 | 55.69 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 986 | 561 | 425 |
| Unadjusted period prevalence (%) | 0.19 | 0.19 | 0.19 |
| Median age at first event (years) | 57.83 | 56.69 | 59.32 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 884
- Matched controls
- 8841
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.19
ICD-10 Finland
Benign tumor of the tongue UNS
+∞
323.0
413
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
60.5
266.4
310
78
D10.12
ICD-10 Finland
Bone tumor of the tip of the tongue
+∞
191.8
177
*
D10.10
ICD-10 Finland
Benign tumor at the base of the tongue
+∞
167.1
155
*
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
191.9
155.2
158
10
D10.11
ICD-10 Finland
Benign tumor in the back of the tongue
+∞
79.4
75
*
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
50.5
58.3
70
15
D10.1
ICD-10 Finland
Benign neoplasm: Tongue
+∞
55.8
53
*
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
181.9
34.0
35
*
8070/3-C02.1
ICD-O-3
Squamous cell carcinoma, NOS, of border of tongue
93.7
33.0
36
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
18.0
32.7
51
30
21010
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Tongue
+∞
30.4
29
*
EJB40
NOMESCO Finland
Hemiglossectomy
110.5
29.8
32
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
15.2
29.5
49
34
D10.14
ICD-10 Finland
Lingual tonsil
155.0
28.8
30
*
D20
ICPC
Mouth/tongue/lip symptom/complaint
5.2
25.1
81
169
K14.9
ICD-10 Finland
Disease of tongue, unspecified
53.5
22.2
26
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
21.9
392
2476
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
10.7
21.8
42
41
A07AA02
ATC
nystatin; oral
3.6
21.7
102
305
SAA03
NOMESCO Finland
Extended examination of mouth
2.1
21.6
361
2215
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.2
21.0
82
208
K13.29
ICD-10 Finland
Indefinite leukoplakia
14.5
21.0
35
25
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
20.0
20.9
31
16
EJB20
NOMESCO Finland
Excision of lesion of base of tongue
112.7
20.6
22
*
D10.13
ICD-10 Finland
Benign tumor under the tongue
+∞
19.9
19
*
UJC01
NOMESCO Finland
Scopy of lower throat
11.0
19.0
36
34
R13
ICD-10 Finland
Dysphagia
3.7
18.9
87
256
8070/3-C01.9
ICD-O-3
Squamous cell carcinoma, NOS, of base of tongue, NOS
+∞
18.8
18
*
K14.61
ICD-10 Finland
Glossodynia
13.5
17.5
30
23
WX110
NOMESCO Finland
Local anesthesy
1.9
17.4
608
4750
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.6
17.1
80
238
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.9
17.1
319
1995
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
16.0
269
1610
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
12.6
15.4
27
22
SXA10
NOMESCO Finland
Epithel biopsy of mouth
8.9
15.3
32
37
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
13.3
15.2
26
20
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.8
15.1
65
181
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
15.4
14.9
24
16
C02.9
ICD-10 Finland
Malignant neoplasm: Tongue, unspecified
57.7
14.8
17
*
2101A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Tongue
+∞
14.6
14
*
C02.10
ICD-10 Finland
Malignant neoplasm of tip of tongue
81.5
14.6
16
*
SAA04
NOMESCO Finland
Special inverstigation of mouth
3.3
14.5
74
237
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.0
13.8
220
1280
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.9
13.4
82
297
ENA10
NOMESCO Finland
Biopsy of pharynx
21.5
13.4
19
9
A01AB09
ATC
miconazole; local oral
2.5
13.2
105
444
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.0
13.1
79
282
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
12.5
266
1704
A02BC05
ATC
esomeprazole; systemic
1.7
12.1
357
2521
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
3.6
12.1
54
156
D37.08
ICD-10 Finland
Tumor of uncertain or unknown nature in other part of lip, oral cavity and pharynx
27.1
12.1
16
6
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
47.3
11.9
14
*
J01DB01
ATC
cefalexin; oral
1.8
11.9
705
6060
A02BC02
ATC
pantoprazole; systemic
1.7
11.7
567
4578
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
11.6
389
2838
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
11.3
94
409
GBB00
NOMESCO Finland
Tracheostomy
6.0
11.3
30
51
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.2
11.1
29
48
K02.1
ICD-10 Finland
Caries of dentine
1.6
11.1
472
3656
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.5
10.9
89
383
J02AC01
ATC
fluconazole; systemic
1.7
10.5
328
2327
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.0
10.2
59
207
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
10.0
581
4810
ZXC10
NOMESCO Finland
Use of laser
4.2
10.0
37
91
N06AX11
ATC
mirtazapine; oral
1.7
10.0
272
1852
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
7.7
9.9
22
29
8070/3-C02.9
ICD-O-3
Squamous cell carcinoma, NOS, of tongue, NOS
20.3
9.8
14
7
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
9.8
394
2971
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
9.8
190
1169
EDB00
NOMESCO Finland
Partial excision of mandible
55.6
9.7
11
*
WF002
NOMESCO Finland
Radical radiotherapy
3.0
9.5
55
193
SDA02
NOMESCO Finland
Parodonthologic therapy
1.7
9.5
271
1864
130
Kela drug reimbursment
Malignant tumour
2.3
9.3
86
393
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
9.3
239
1598
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.9
9.2
36
94
K13.78
ICD-10 Finland
Other change in the oral mucosa
4.4
9.2
32
75
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
37.1
9.0
11
*
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
9.6
8.8
17
18
N02BE01
ATC
paracetamol; systemic, rectal
1.7
8.8
744
6661
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.1
8.8
47
158
D10.39
ICD-10 Finland
Benign tumor in other or unspecified part of oral cavity UNS
16.5
8.6
13
8
D02
ICPC
Abdominal pain epigastric
2.7
8.4
55
211
N05BA04
ATC
oxazepam; oral
1.7
8.4
217
1449
4399
FHL
Other measure in this category
+∞
8.3
8
*
C02.1
ICD-10 Finland
Malignant neoplasm: Border of tongue
+∞
8.3
8
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
8.3
211
1401
R4110
NOMESCO Finland
Physiotherapy
1.6
8.3
230
1565
J01FA10
ATC
azithromycin; systemic
1.5
8.2
463
3722
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
8.2
290
2096
N05CF01
ATC
zopiclone; oral
1.6
8.2
281
2016
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
11.8
8.1
14
12
PJD51
NOMESCO Finland
Block dissection of cervical lymph nodes
33.7
8.1
10
*
S29
ICPC
Skin symptom/complaint other
1.8
8.1
150
907
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
8.0
450
3607
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.6
8.0
298
2177
D07AC13
ATC
mometasone; topical
1.6
8.0
239
1655
WX402
NOMESCO Finland
General anaesthesia
1.8
7.9
142
849
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
7.9
427
3394
Z01.9
ICD-10 Finland
Special examination, unspecified
2.6
7.9
57
230
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
7.8
197
1304
N02AA05
ATC
oxycodone; systemic
1.8
7.7
134
791
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
7.7
509
4207
ZX095
NOMESCO Finland
Combined chemoradiotherapy
12.0
7.6
13
11
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.3
7.4
35
108
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
7.4
169
1082
EJB00
NOMESCO Finland
Excision of ranula
80.7
7.4
8
*
4392
FHL
Tongue and / or Mouth resection or excision
80.7
7.4
8
*
EJW99
NOMESCO Finland
Other operation on tongue or floor of mouth
+∞
7.3
7
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
7.3
100
543
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
7.3
312
2344
EBA10
NOMESCO Finland
Surgical removal of tooth
2.0
7.2
92
487
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
7.2
171
1111
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
30.3
7.2
9
*
K13.2
ICD-10 Finland
Leukoplakia and other disturbances of oral epithelium, including tongue
20.2
7.1
10
5
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.4
7.1
56
238
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
7.1
206
1409
R01AD09
ATC
mometasone; nasal
1.5
7.1
350
2708
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
7.0
100
552
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.5
7.0
52
214
S18
ICPC
Laceration/cut
1.5
6.9
352
2737
SBA00
NOMESCO Finland
Microbiological examinations
3.3
6.9
33
104
R01AD08
ATC
fluticasone; nasal
1.6
6.8
227
1605
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
6.8
328
2519
K14.09
ICD-10 Finland
Glossit UNS
40.3
6.8
8
*
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
40.3
6.8
8
*
K14.5
ICD-10 Finland
Plicated tongue
16.8
6.8
10
6
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
6.5
6.7
16
25
UJF32
NOMESCO Finland
Coloscopy
1.6
6.6
214
1501
L14
ICPC
Leg/thigh symptom/complaint
2.2
6.5
67
324
D10.2
ICD-10 Finland
Benign neoplasm: Floor of mouth
70.3
6.4
7
*
A02BC01
ATC
omeprazole; systemic
1.5
6.4
229
1642
J01MA12
ATC
levofloxacin; systemic
1.6
6.4
155
1011
UJD02
NOMESCO Finland
Gastroscopy
2.5
6.4
48
199
K05.31
ICD-10 Finland
Periodontitis pronounced
1.9
6.4
91
502
L02
ICPC
Back symptom/complaint
2.0
6.3
73
372
Z50.5
ICD-10 Finland
Speech therapy
6.0
6.3
16
27
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
6.3
546
4674
C02.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tongue
+∞
6.3
6
*
C02.0
ICD-10 Finland
Malignant neoplasm: Dorsal surface of tongue
26.9
6.2
8
*
K14.88
ICD-10 Finland
Other diseases of tongue
26.9
6.2
8
*
B37.0
ICD-10 Finland
Candidal stomatitis
6.3
6.2
15
24
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
6.2
334
2614
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.1
133
841
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
6.1
67
333
E0000UV
ATC
NA
1.5
6.1
309
2383
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.1
347
2739
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
6.1
223
1607
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
8.7
6.1
12
14
R03BA05
ATC
fluticasone; inhalant
1.6
6.0
144
933
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.7
6.0
37
139
N06AA09
ATC
amitriptyline; systemic
1.9
6.0
90
506
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
583
4371
1.82
18.10
7.4
6.3
11.2
11.2
umol/l
0.04
545
4141
43
97
4.59
17.90
2.3
1.3
—
—
—
0
0
772
6337
2.01
17.87
9.9
7.7
78.2
78.7
u/l
0.17
728
5949
490
3548
1.76
16.56
5.8
4.8
35.4
35.4
g/l
0.07
455
3292
546
4106
1.74
15.89
8.0
6.7
1.2
1.2
mmol/l
0.26
461
3487
607
4719
1.74
15.52
11.5
9.1
4.1
4.1
e9/l
0.18
534
4150
503
3769
1.68
14.22
7.0
5.9
1.2
1.2
mmol/l
0.21
448
3406
170
924
2.01
14.10
3.1
2.7
9.0
8.4
umol/l
0.11
143
812
662
5368
1.71
13.59
5.6
4.5
2923.3
2941.2
e6/l
0.00
14
89
356
2489
1.67
12.72
3.4
3.3
236.7
82.2
e6/l
0.35
258
1928
143
763
2.02
12.41
2.6
2.4
32.7
40.3
u/l
0.63
120
644
216
1327
1.80
12.20
2.9
2.9
1.4
2.3
e6/l
1.81
116
723
603
4841
1.63
12.18
5.7
4.7
6.7
6.7
mmol/l
0.00
576
4541
331
2293
1.67
12.13
3.4
3.1
0.3
0.4
e6/l
1.54
236
1735
716
6074
1.65
10.92
4.7
4.1
13.1
12.6
mm/h
0.38
651
5600
214
1352
1.74
10.86
5.0
3.2
0.8
0.8
mmol/l
1.30
200
1263
222
1421
1.73
10.74
2.8
2.7
0.7
1.1
e6/l
2.73
123
816
91
433
2.21
10.61
7.5
9.8
25.0
24.5
mmol/l
1.05
86
405
239
1568
1.69
10.54
3.8
3.8
379.8
404.8
ng/l
0.05
185
1226
359
2621
1.58
10.25
4.0
3.2
32.9
32.4
u/l
0.07
331
2494
115
608
2.01
10.18
2.0
1.6
—
—
—
0
0
888
8077
2.00
9.80
22.2
14.5
27.5
24.0
mg/l
1.73
735
6405
380
2837
1.55
9.71
4.8
3.4
2.4
2.4
mmol/l
0.69
327
2462
443
3423
1.53
9.67
2.3
2.0
95.7
95.5
pmol/l
0.03
200
1757
282
1978
1.60
9.40
2.9
2.3
—
—
—
0
0
717
6198
1.57
8.99
4.6
3.9
14.8
14.9
pmol/l
0.31
647
5604
129
747
1.84
8.68
6.8
6.6
1.3
1.4
mmol/l
0.44
122
715
910
8425
2.04
8.36
24.0
16.8
139.4
139.7
mmol/l
2.87
891
8210
430
3389
1.48
8.07
3.2
2.7
132.0
133.8
ug/l
0.05
398
3108
172
1108
1.67
7.94
2.6
2.4
21.4
22.8
%
0.57
153
958
910
8451
2.00
7.88
24.4
16.9
3.9
4.0
mmol/l
2.56
888
8223
426
3368
1.47
7.78
2.6
2.2
79.4
77.6
nmol/l
0.57
375
2988
345
2628
1.48
7.56
2.7
2.5
55.8
56.4
u/l
0.07
310
2426
126
757
1.76
7.48
2.9
2.1
380.5
374.0
nmol/l
0.12
108
693
50
216
2.39
7.34
3.1
2.9
1.3
1.6
mg/l
1.77
45
197
278
2039
1.51
7.30
2.7
2.1
2.7
3.1
mg/l
1.79
233
1737
189
1275
1.60
7.22
1.9
2.0
29.8
29.6
s
0.24
183
1229
178
1184
1.61
7.20
2.5
2.3
2.3
2.3
g/l
0.04
165
1105
223
1565
1.55
7.17
4.0
3.1
2.5
2.5
mmol/l
0.84
197
1369
820
7439
1.61
7.13
5.7
4.7
1.9
2.1
mu/l
0.46
745
6768
164
1074
1.63
7.06
25.3
24.8
1.3
1.3
inr
0.09
23
138
471
3846
1.43
7.00
4.5
3.9
—
—
—
0
0
330
2530
1.46
6.86
2.2
2.1
185.4
250.4
u/l
0.81
311
2384
239
1718
1.52
6.85
2.7
2.6
5.5
6.1
e6/l
0.25
197
1525
145
928
1.66
6.82
5.0
4.2
245.8
247.0
u/l
0.02
140
874
268
1986
1.48
6.59
1.8
1.6
22.6
20.9
nmol/l
1.13
220
1673
73
385
1.97
6.53
3.4
3.5
25.4
24.2
mmol/l
2.20
67
346
195
1356
1.55
6.48
2.1
1.9
—
—
—
0
0
556
4730
1.40
6.26
3.0
2.8
—
—
—
0
0
40
169
2.42
6.20
1.4
1.4
12.9
10.5
u/l
0.40
35
133
175
1202
1.55
6.12
1.5
1.4
—
—
—
0
0
185
1288
1.54
6.09
2.6
2.3
12.5
13.0
umol/l
0.41
169
1188
79
442
1.86
5.94
2.7
3.4
4.5
4.5
pmol/l
0.09
69
379
11
20
5.55
5.81
2.0
1.3
0.2
0.4
ug/l
—
6
12
144
958
1.59
5.78
2.0
1.8
—
—
—
0
0
116
736
1.65
5.63
7.3
6.7
8.5
9.8
mmol/l
1.38
110
698
86
506
1.77
5.50
2.0
1.7
—
—
—
0
0
124
807
1.61
5.45
2.9
2.2
0.2
0.2
g/l
1.30
115
752
834
7711
1.53
5.44
20.3
13.5
80.0
79.6
ml/min/173m2
0.25
708
6364
45
213
2.17
5.40
1.2
1.2
—
—
—
0
0
913
8631
1.78
5.40
13.9
10.7
25.8
26.4
u/l
0.66
885
8315
92
556
1.72
5.36
2.4
2.2
13.0
12.9
nmol/l
0.04
82
493
475
4004
1.36
5.30
5.9
5.2
0.0
0.0
estimate
0.00
84
757
477
4045
1.35
5.03
4.2
3.8
0.0
0.0
estimate
0.80
81
731
240
1822
1.42
5.03
1.9
1.6
1.1
1.2
mg/l
0.10
184
1397
14
36
3.93
5.00
4.7
4.4
—
—
—
0
0
791
7270
1.45
4.99
23.6
15.7
39.5
39.7
%
0.15
580
5109
855
7981
1.54
4.97
5.3
4.7
6.0
6.0
mmol/l
0.01
763
7238
209
1554
1.44
4.90
1.9
1.7
1151.6
1215.1
nmol/l
0.37
144
1150
469
3985
1.34
4.80
4.2
3.8
0.0
0.0
estimate
0.00
82
751
140
966
1.52
4.77
2.0
1.9
—
—
—
0
0
118
784
1.57
4.76
3.8
3.3
2.6
2.0
mmol/l
0.99
106
620
155
1098
1.49
4.65
7.1
5.4
1.0
1.0
mmol/l
0.29
150
1008
25
98
2.59
4.58
3.0
3.7
—
—
—
0
0
32
142
2.30
4.51
1.2
1.3
—
—
—
0
0
24
94
2.59
4.41
1.2
1.2
52.7
50.7
u/l
0.08
18
70
733
6698
1.37
4.38
25.9
17.8
13.8
13.7
%
0.50
722
6552
600
5328
1.32
4.32
3.9
3.2
51.9
51.4
u/l
0.04
548
4954
149
1066
1.47
4.25
7.7
6.7
104.3
104.2
mmol/l
0.19
142
1038
225
1735
1.38
4.24
1.3
1.2
0.7
1.4
u/ml
1.86
58
464
306
2486
1.33
4.10
3.0
3.0
1257.9
1217.6
ng/l
0.07
266
2110
7
7
10.06
4.01
1.3
1.1
—
—
—
0
0
136
967
1.47
4.00
7.1
7.4
1.0
1.2
mmol/l
0.13
113
767
13
38
3.45
3.91
1.0
1.0
—
—
—
0
0
131
930
1.47
3.89
2.4
1.8
1.6
1.5
%
0.24
110
810
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
46
250
1.88
3.86
2.3
2.6
0.3
0.4
u/ml
0.22
20
145
121
854
1.48
3.70
3.5
3.2
—
—
—
0
0
34
169
2.05
3.68
1.6
1.4
—
—
—
0
0
34
169
2.05
3.68
1.6
1.4
—
—
—
0
0
134
969
1.44
3.62
7.2
7.4
5.2
5.1
kpa
0.36
127
930
134
969
1.44
3.62
7.2
7.4
12.5
12.1
kpa
0.34
126
933
933
8988
1.71
3.60
31.0
21.5
133.3
135.2
g/l
3.35
921
8842
13
42
3.12
3.38
2.1
2.3
—
—
—
0
0
44
248
1.81
3.33
1.5
1.5
253.6
284.8
ug/g
0.49
26
147
61
387
1.61
3.04
1.8
1.9
1.6
1.5
g/l
0.25
51
338
19
83
2.31
2.85
1.9
1.6
—
—
—
0
0
14
53
2.67
2.80
1.1
1.5
—
217.5
—
0
8
37
210
1.79
2.78
2.0
1.7
16325.7
15799.5
e6/l
0.03
28
155
27
138
1.98
2.77
5.0
3.9
1.0
1.4
%
0.34
21
118
42
248
1.72
2.76
1.7
1.7
—
—
—
0
0
35
197
1.81
2.71
1.2
1.3
—
—
—
0
0
6
10
6.03
2.70
1.0
1.1
—
—
—
0
0
6
10
6.03
2.70
1.0
1.1
—
—
—
0
0
37
213
1.77
2.66
1.9
2.6
3.7
3.6
g/l
0.13
37
203
13
49
2.68
2.63
1.3
1.3
—
—
—
0
0
28
149
1.90
2.58
1.6
1.7
—
—
—
0
0
120
906
1.37
2.56
3.9
4.3
8.2
25.9
ug/l
1.08
102
752
20
96
2.11
2.44
1.4
1.7
—
—
—
0
0
33
189
1.77
2.44
1.4
1.7
2.7
4.7
iu/l
—
9
56
6
12
5.02
2.40
1.3
1.5
—
—
—
0
0
83
595
1.43
2.40
2.9
1.9
—
—
—
0
0
29
161
1.83
2.37
2.6
2.0
980.2
4143.3
u/l
—
8
56
22
111
2.00
2.37
1.4
1.2
3.5
7.8
u/ml
0.77
11
46
16
71
2.27
2.35
1.4
1.2
—
—
—
0
0
46
292
1.60
2.35
2.5
2.9
—
—
—
0
0
10
35
2.88
2.31
2.4
3.0
226.5
197.3
u/l
—
10
35
38
231
1.67
2.29
1.5
1.6
—
—
—
0
0
307
2654
1.23
2.29
4.5
4.8
1.8
2.4
ug/l
1.95
277
2370
48
310
1.58
2.29
4.0
2.4
3.1
3.1
g/l
0.02
38
243
16
72
2.24
2.28
1.0
1.4
—
—
—
0
0
6
13
4.64
2.27
1.3
1.3
—
—
—
0
0
49
320
1.56
2.23
2.0
1.9
—
—
—
0
0
75
536
1.43
2.22
2.7
1.8
—
—
—
0
0
22
114
1.95
2.21
1.6
1.4
—
—
—
0
0
70
494
1.45
2.21
1.7
1.5
—
—
—
0
0
5
9
5.58
2.21
2.8
1.1
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
8
24
3.35
2.18
1.4
2.3
202.6
135.9
%
—
8
24
798
7601
1.26
2.18
6.5
5.9
40.1
40.1
mmol/mol
0.01
726
7034
21
108
1.96
2.16
1.1
1.1
—
—
—
0
0
30
174
1.75
2.15
1.2
1.4
—
—
—
0
0
21
109
1.95
2.11
1.3
1.2
1.3
1.8
u/ml
0.90
11
31
143
1141
1.30
2.11
1.6
1.4
—
—
—
0
0
255
2179
1.23
2.11
2.7
2.6
2876.3
6577.4
umol/l
1.10
221
1875
12
49
2.47
2.11
1.3
1.3
—
—
—
0
0
34
206
1.67
2.10
1.5
1.6
—
—
—
0
0
44
285
1.57
2.09
4.4
3.8
25.8
41.9
mg/l
0.81
30
230
40
254
1.60
2.06
1.5
1.2
—
—
—
0
0
15
69
2.19
2.05
1.1
1.1
—
—
u/ml
—
0
0
365
3242
1.20
2.02
4.4
3.7
40.0
47.0
ng/l
0.19
254
2317
17
83
2.07
2.02
1.1
1.3
5468.3
222258.2
e6/l
1.13
11
58
13
57
2.30
1.98
1.1
1.1
—
—
—
0
0
13
57
2.30
1.98
1.1
1.1
—
—
—
0
0
21
112
1.89
1.97
1.7
1.4
—
—
—
0
0
5
11
4.56
1.94
1.2
1.3
144.8
103.9
%
—
5
11
260
2245
1.21
1.93
1.7
1.6
1.4
1.4
mmol/l
0.27
215
1887
67
483
1.42
1.92
1.2
1.3
192.6
251.0
u/ml
0.32
62
440
13
58
2.26
1.91
1.1
1.1
—
—
—
0
0
13
58
2.26
1.91
1.2
1.2
—
—
—
0
0
13
58
2.26
1.91
1.1
1.1
—
—
—
0
0
13
58
2.26
1.91
1.1
1.1
—
—
—
0
0
17
85
2.02
1.91
2.0
2.2
—
—
—
0
0
21
114
1.86
1.88
1.7
1.4
—
—
—
0
0
204
1723
1.23
1.87
1.8
1.7
93293143.1
16842539.4
pmol/l
0.57
164
1425
43
285
1.53
1.87
4.4
3.8
90.4
70.9
mg/l
0.12
30
229
31
190
1.65
1.86
1.6
1.4
—
—
—
0
0
10
40
2.52
1.84
1.4
1.3
—
—
—
0
0
10
40
2.52
1.84
1.4
1.3
—
—
—
0
0
5
12
4.18
1.82
1.0
1.0
—
—
—
0
0
32
199
1.63
1.82
1.6
1.7
—
—
—
0
0
48
330
1.48
1.78
3.9
2.4
3.8
3.8
g/l
0.03
38
238
48
330
1.48
1.78
4.0
2.4
—
—
—
0
0
48
330
1.48
1.78
4.0
2.4
7.2
7.4
g/l
0.25
40
250
10
41
2.45
1.76
2.1
3.2
616.2
1148.7
u/ml
—
10
41
87
666
1.34
1.75
2.7
2.9
261.7
190.3
ng/l
0.43
80
606
26
157
1.67
1.67
2.5
3.6
58.3
57.7
%
0.10
26
157
20
112
1.80
1.65
1.6
1.4
—
—
—
0
0
20
112
1.80
1.65
1.6
1.4
—
—
—
0
0
70
525
1.36
1.62
1.3
1.2
158.2
151.6
iu/ml
0.04
22
211
85
657
1.32
1.62
3.0
2.7
68.4
64.9
ml/min/173m2
0.39
39
270
20
113
1.79
1.61
1.6
1.4
—
—
—
0
0
10
43
2.34
1.60
1.1
1.1
—
—
—
0
0
43
297
1.47
1.58
1.9
1.7
—
—
—
0
0
7
26
2.70
1.58
1.6
1.1
10.5
8.9
ug/l
—
7
26
25
153
1.65
1.54
2.4
3.2
4.1
4.3
e9/l
0.13
25
153
8
33
2.44
1.54
2.0
2.0
—
—
—
0
0
8
33
2.44
1.54
2.0
2.0
—
—
—
0
0
20
115
1.75
1.53
3.9
2.1
441.0
38.3
u/ml
0.43
20
110
46
640
0.70
1.53
2.1
1.7
—
—
—
0
0
71
541
1.34
1.50
2.5
2.5
—
17.6
—
0
21
12
58
2.08
1.49
1.3
1.4
—
21.0
—
0
9
21
124
1.71
1.48
1.4
1.6
—
—
—
0
0
6
22
2.74
1.43
2.7
1.5
—
—
—
0
0
19
110
1.74
1.43
1.2
1.1
0.3
2.1
u/ml
—
6
42
89
706
1.29
1.43
3.9
2.9
66.1
67.0
g/l
0.53
83
641
10
46
2.19
1.40
2.3
1.4
—
—
—
0
0
10
46
2.19
1.40
2.3
1.4
—
—
—
0
0
54
400
1.37
1.38
1.0
1.0
—
—
—
0
0
43
309
1.41
1.32
4.1
2.4
9.6
10.8
g/l
0.95
38
261
8
34
2.36
1.29
2.0
2.0
—
—
—
0
0
8
36
2.23
1.24
1.0
1.3
—
—
—
0
0
13
71
1.84
1.19
1.6
1.7
—
—
—
0
0
24
158
1.53
1.15
1.8
1.9
169.6
211.1
pmol/l
1.26
24
147
28
191
1.48
1.15
2.0
2.1
136.1
131.2
g/l
0.41
18
146
82
666
1.25
1.12
4.6
3.7
1.2
1.2
mmol/l
0.85
70
583
33
234
1.42
1.12
1.5
1.4
—
—
—
0
0
7
32
2.20
1.08
1.1
1.4
—
—
—
0
0
36
263
1.38
1.05
1.6
2.0
—
—
—
0
0
23
154
1.51
1.04
1.3
1.5
—
—
—
0
0
9
46
1.97
1.03
1.2
1.4
—
—
—
0
0
9
46
1.97
1.03
1.4
1.4
11.7
14.6
u/l
—
9
41
17
106
1.61
1.03
1.1
1.1
—
—
—
0
0
9
47
1.92
1.02
1.4
1.2
—
—
—
0
0
33
239
1.39
1.01
1.2
1.2
—
—
—
0
0
12
68
1.77
1.00
1.1
1.0
288.7
298.3
mg/l
0.19
12
58
9
48
1.88
1.00
2.2
3.1
—
—
—
0
0
9
49
1.84
0.98
1.6
1.6
—
—
—
0
0
9
49
1.84
0.98
1.6
1.6
—
—
—
0
0
30
215
1.41
0.98
1.9
1.6
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
5
23
2.18
0.98
2.2
1.3
1.5
2.5
mmol/l
—
5
23
9
51
1.77
0.94
4.2
1.6
—
—
—
0
0
30
217
1.39
0.94
1.4
1.2
5.8
10.7
u/ml
—
5
34
6
27
2.23
0.93
1.3
1.3
—
—
—
0
0
238
2161
1.13
0.93
4.5
4.1
0.0
0.0
estimate
0.88
84
737
79
656
1.22
0.92
4.1
3.7
89.7
85.1
ng/l
0.09
63
580
49
385
1.29
0.91
1.4
1.3
—
—
—
0
0
8
43
1.87
0.87
2.0
1.8
—
—
—
0
0
8
43
1.87
0.87
2.0
1.8
—
—
—
0
0
8
43
1.87
0.87
2.0
1.8
—
—
—
0
0
8
43
1.87
0.87
2.0
1.8
—
—
—
0
0
20
136
1.48
0.87
1.4
1.2
533.5
303.5
u/ml
0.53
14
80
32
238
1.36
0.87
1.2
1.2
—
—
—
0
0
21
145
1.46
0.85
1.3
1.2
—
—
—
0
0
22
308
0.71
0.84
3.8
4.0
1.8
1.3
mmol/l
0.63
22
301
24
171
1.41
0.83
2.0
3.6
68.4
2143.0
u/ml
0.81
24
163
842
8239
1.15
0.83
5.6
5.1
2.8
2.8
mmol/l
0.69
762
7545
8
46
1.75
0.82
1.0
1.1
70.2
88.2
u/l
—
8
35
8
46
1.75
0.82
1.0
1.1
33.9
28.8
u/l
—
8
34
6
32
1.88
0.82
1.2
3.5
—
63687.9
—
0
7
27
199
1.37
0.79
1.5
1.4
—
—
—
0
0
44
349
1.27
0.78
2.2
1.9
1.8
2.2
ug/l
0.09
36
312
18
123
1.47
0.78
1.3
1.5
—
—
—
0
0
0
27
0.00
0.77
0.0
1.0
—
1630.5
—
0
27
27
200
1.36
0.77
1.4
1.3
156.9
237.8
miu/ml
0.57
14
89
10
59
1.70
0.76
1.1
1.2
—
—
—
0
0
330
3091
1.10
0.74
4.6
4.0
—
—
—
0
0
10
60
1.67
0.72
1.1
1.2
—
—
—
0
0
7
40
1.76
0.71
1.0
1.1
—
—
—
0
0
7
41
1.71
0.70
28.4
19.1
1615.7
1602.0
nmol/l
—
7
41
64
539
1.20
0.69
5.5
3.3
1.9
1.9
mmol/l
0.04
48
416
43
347
1.25
0.69
3.8
3.3
256.4
4034.7
u/ml
0.72
38
298
9
59
1.53
0.68
1.6
1.5
—
—
—
0
0
819
8028
1.12
0.66
5.0
4.5
1.5
1.5
mmol/l
0.40
739
7350
24
180
1.34
0.65
2.8
2.4
19.0
16.4
%
—
10
102
230
2129
1.10
0.65
3.7
4.2
20.0
21.3
%
0.62
89
998
30
233
1.30
0.65
1.6
1.4
—
—
—
0
0
156
1415
1.12
0.64
1.3
1.3
37.4
34.6
iu/ml
0.10
49
464
8
127
0.63
0.64
1.0
1.1
—
155.5
—
0
24
823
8080
1.11
0.60
5.1
4.5
4.7
4.7
mmol/l
0.28
749
7450
192
1771
1.10
0.59
3.9
4.1
1.0
1.0
kg/l
0.08
23
241
170
1559
1.11
0.58
2.7
2.9
0.7
0.7
ug/l
0.71
116
1022
7
116
0.60
0.57
1.0
1.1
—
—
—
0
0
21
158
1.34
0.57
2.1
1.6
—
—
—
0
0
34
274
1.25
0.57
2.6
1.8
—
—
—
0
0
12
81
1.49
0.57
1.6
1.3
33820.0
48941.8
e6/l
—
6
46
5
88
0.57
0.56
2.0
1.5
—
—
—
0
0
5
81
0.62
0.46
1.0
1.1
—
—
—
0
0
7
50
1.40
0.45
1.4
1.4
—
—
—
0
0
7
51
1.38
0.44
1.6
1.8
—
—
—
0
0
144
1339
1.09
0.40
1.2
1.3
1.8
14.0
u/ml
7.47
34
516
14
106
1.33
0.39
1.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.8
1.1
5.9
6.5
mmol/l
—
5
36
9
70
1.29
0.36
1.1
1.1
—
—
—
0
0
26
217
1.20
0.35
2.7
1.7
—
—
—
0
0
46
404
1.15
0.35
5.2
3.4
47.8
48.6
%
0.07
46
399
10
73
1.37
0.34
3.5
2.5
—
—
—
0
0
17
136
1.25
0.33
1.4
1.5
—
—
—
0
0
112
1041
1.09
0.33
7.6
7.2
—
—
—
0
0
17
209
0.81
0.32
1.3
1.3
576.5
518.4
mg/l
0.20
17
195
10
74
1.35
0.32
1.0
1.0
—
—
—
0
0
40
351
1.15
0.32
2.4
2.1
40.8
40.5
u/l
0.03
35
307
12
92
1.31
0.32
1.8
1.8
—
—
—
0
0
7
52
1.35
0.31
1.1
1.0
169.0
332.7
ng/l
—
7
30
7
52
1.35
0.31
1.1
1.0
14.7
51.0
ng/l
—
7
28
7
52
1.35
0.31
1.1
1.0
849.9
635.4
ng/l
—
7
30
7
54
1.30
0.30
2.4
1.4
0.9
1.0
g/l
—
7
54
80
738
1.09
0.29
2.3
2.5
8.7
7.0
ug/l
0.27
65
648
11
85
1.30
0.28
1.8
1.8
—
—
—
0
0
15
122
1.23
0.27
1.4
1.5
—
—
—
0
0
8
67
1.20
0.26
1.1
1.5
—
—
—
0
0
10
77
1.30
0.26
1.8
1.6
—
—
—
0
0
10
77
1.30
0.26
1.8
1.6
—
—
—
0
0
10
77
1.30
0.26
1.8
1.6
—
—
—
0
0
5
72
0.69
0.26
1.2
1.2
1.2
1.4
nmol/l
—
5
64
12
96
1.25
0.24
1.0
1.4
—
—
—
0
0
12
96
1.25
0.24
1.0
1.4
—
—
—
0
0
12
96
1.25
0.24
1.0
1.4
—
—
—
0
0
12
96
1.25
0.24
1.0
1.4
—
—
—
0
0
6
85
0.70
0.24
3.7
2.1
13.2
13.2
%
—
6
85
23
199
1.16
0.23
1.3
1.1
—
—
—
0
0
270
2616
1.04
0.23
3.6
3.1
7.3
7.5
mmol/l
0.31
226
2200
5
38
1.32
0.23
1.6
1.7
67.8
53.8
ug/l
—
5
38
5
41
1.22
0.22
1.2
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.6
—
0.6
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
51
1.18
0.19
1.3
1.3
4.8
6.5
u/l
—
6
39
782
7753
1.04
0.19
4.5
4.1
1.4
1.3
mmol/l
1.14
701
7058
22
194
1.14
0.18
4.4
3.6
37.6
24.9
mg/l
0.67
17
121
7
59
1.19
0.18
1.3
1.2
—
—
—
0
0
22
247
0.89
0.17
1.8
1.8
—
—
—
0
0
16
139
1.15
0.16
1.3
1.1
—
—
—
0
0
111
1065
1.05
0.16
4.8
4.5
32.1
32.5
%
0.11
68
707
268
2627
1.03
0.13
4.7
4.0
17.1
8.1
mg/mmol
0.61
173
1656
5
44
1.14
0.10
5.2
2.1
732.8
639.9
e6/l
—
5
39
5
46
1.09
0.09
1.2
1.3
0.9
2.8
ug/l
—
5
37
26
245
1.06
0.07
1.7
1.6
0.3
0.1
iu/ml
—
9
39
9
84
1.07
0.07
1.2
1.1
—
—
—
0
0
9
88
1.02
0.07
1.2
1.1
—
—
—
0
0
12
109
1.10
0.06
1.8
1.7
—
—
—
0
0
39
402
0.97
0.04
4.6
3.5
18.8
54.2
u/ml
2.25
39
387
11
119
0.92
0.04
1.1
1.6
—
—
—
0
0
17
179
0.95
0.03
1.4
1.2
1.2
32.8
e6/l
—
9
141
17
179
0.95
0.03
1.5
1.3
2736.3
794.7
e6/l
0.30
11
144
11
102
1.08
0.03
1.1
1.5
—
—
—
0
0
30
293
1.02
0.01
1.5
1.8
3.4
5.0
mg/l
0.34
22
231
18
186
0.97
0.00
1.4
1.5
—
—
—
0
0
18
177
1.02
0.00
1.3
1.8
0.8
0.9
nmol/l
0.24
13
150
21
215
0.98
0.00
1.3
1.4
—
—
—
0
0
20
205
0.98
0.00
1.9
2.5
24.7
86.9
ug/min
2.08
11
122
7
72
0.97
0.00
1.1
1.0
—
—
—
0
0
5
50
1.00
0.00
1.2
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
5.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
15.8
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
7
71
0.99
0.00
3.7
1.7
—
2.2
—
0
29
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_TONGUE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TONGUE | 1.22 [1.08, 1.38] | 0.002 |
| Birth year | 1.0 [0.99, 1.01] | 0.949 |
During the follow-up period (1.1.1998 — 31.12.2019), 623 out of 3101 females with CD2_BENIGN_TONGUE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TONGUE | 1.408 [1.23, 1.62] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 571 out of 2502 males with CD2_BENIGN_TONGUE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_TONGUE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.111% | 0.245% |
| 5 | 0.783% | 1.485% |
| 10 | 2.157% | 3.893% |
| 15 | 4.34% | 7.444% |
| 20 | 7.575% | 12.598% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_TONGUE – Benign neoplasm: Tongue
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data