This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Problems related to education and literacy
Z21_PROBL_RELATED_EDUCATION_LITER
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
94 |
4. Check minimum number of eventsNone |
94 |
5. Include endpointsNone |
94 |
6. Filter based on genotype QC (FinnGen only) |
94 |
Control definitions (FinnGen only)
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Z5[5-9]|Z6
Similar endpoints
↥List of similar endpoints to
Problems related to education and literacy
based on the number of shared cases.
Similar with more cases:
- Persons with potential health hazards related to socioeconomic and psychosocial circumstances
- Factors influencing health status and contact with health services
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 94 | 52 | 42 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 15.49 | 15.81 | 15.08 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 85
- Matched controls
- 847
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z55.4
ICD-10 Finland
Educational maladjustment and discord with teachers and classmates
+∞
31.2
28
*
Z55.9
ICD-10 Finland
Problem related to education and literacy, unspecified
+∞
17.3
16
*
Z55.8
ICD-10 Finland
Other problems related to education and literacy
+∞
13.9
13
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
7.2
13.5
38
86
N05AH04
ATC
quetiapine; oral
6.2
11.6
36
90
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
6.0
10.7
33
81
Z55.0
ICD-10 Finland
Illiteracy and low-level literacy
+∞
10.6
10
*
Z55.3
ICD-10 Finland
Underachievement in school
+∞
10.6
10
*
N06AB03
ATC
fluoxetine; oral
6.6
8.7
23
45
F93.89
ICD-10 Finland
Other childhood emotional disorders
17.8
7.5
11
7
N06AB10
ATC
escitalopram; oral
3.8
7.1
36
137
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
5.3
7.1
22
52
N05AX12
ATC
aripiprazole; systemic
6.2
6.8
18
35
WX290
NOMESCO Finland
Other blockade of nerve
3.5
6.5
62
370
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
+∞
6.3
6
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
9.8
6.3
12
14
N06AX12
ATC
bupropion; oral
6.1
6.1
16
31
N06AB04
ATC
citalopram; systemic
4.4
6.0
22
62
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
10
20
5.48
4.90
28.1
16.0
94.32
94.36
%
—
10
20
10
20
5.48
4.90
28.1
16.1
0.87
0.76
%
—
10
20
10
20
5.48
4.90
27.8
16.1
1.64
1.64
%
—
10
20
35
184
2.44
3.95
2.7
4.6
36.71
38.20
g/l
0.50
30
174
9
15
6.51
3.92
1.3
1.1
—
—
—
0
0
9
17
5.73
3.61
1.3
1.1
—
—
—
0
0
38
238
2.00
2.62
8.7
7.5
1.20
1.22
mmol/l
0.94
32
197
85
744
2.49
2.18
14.4
9.1
26.63
20.89
mg/l
0.71
66
552
40
272
1.82
2.06
2.3
1.7
—
—
—
0
0
53
400
1.75
1.87
9.4
8.0
4.40
4.07
e9/l
0.45
45
352
5
12
4.33
1.84
1.0
1.0
—
—
—
0
0
5
12
4.33
1.84
1.0
1.0
—
—
—
0
0
75
631
1.93
1.78
3.3
2.8
5.52
5.48
mmol/l
0.14
70
576
6
18
3.49
1.77
1.0
1.2
307.67
331.28
mg/l
—
6
18
13
65
2.16
1.57
1.7
1.4
371.08
417.27
nmol/l
0.35
13
56
30
202
1.71
1.53
2.1
2.9
—
—
—
0
0
20
123
1.80
1.38
1.3
1.3
4.77
6.64
u/ml
—
9
51
5
18
2.87
1.30
1.0
1.5
11.20
78.44
e6/l
—
5
18
14
78
1.93
1.29
1.4
2.4
5.07
3.45
e6/l
—
6
38
6
25
2.49
1.26
19.7
5.6
25.08
25.94
mmol/l
—
6
25
39
294
1.56
1.25
3.6
3.0
—
—
—
0
0
46
361
1.54
1.22
3.6
2.9
0.00
0.00
estimate
—
7
84
28
196
1.61
1.22
2.8
2.4
99.78
56.52
u/l
0.45
23
183
47
371
1.53
1.21
3.6
3.0
0.00
0.00
estimate
—
9
80
65
734
0.63
1.18
3.8
4.0
—
—
—
0
0
26
180
1.61
1.18
1.5
1.5
82.49
93.66
pmol/l
1.17
14
99
46
364
1.52
1.16
4.8
3.9
0.00
0.00
estimate
—
9
85
10
52
2.03
1.11
2.0
1.2
—
—
—
0
0
30
219
1.54
1.08
3.6
3.3
0.00
0.01
estimate
—
9
82
10
53
1.99
1.06
2.1
1.2
—
—
—
0
0
11
61
1.91
1.03
1.1
1.0
—
—
—
0
0
7
35
2.08
1.02
1.4
1.5
—
—
—
0
0
73
648
1.57
0.99
10.1
7.0
103.10
101.94
ml/min/173m2
0.17
56
497
13
81
1.70
0.86
1.9
1.7
—
—
—
0
0
5
99
0.48
0.83
1.0
1.4
—
—
—
0
0
6
34
1.82
0.77
4.2
1.5
—
—
—
0
0
5
24
2.14
0.76
1.0
1.1
—
—
—
0
0
7
42
1.72
0.70
1.4
1.4
—
—
—
0
0
5
29
1.76
0.64
1.2
1.4
22.00
34.03
nmol/l
—
5
29
27
334
0.73
0.64
5.0
4.2
—
—
—
0
0
18
132
1.45
0.63
2.8
1.6
0.78
0.68
mg/l
0.16
13
92
5
30
1.70
0.62
1.2
1.3
—
—
—
0
0
12
81
1.55
0.60
3.7
3.0
24.40
122.82
ng/l
—
5
44
30
246
1.32
0.55
1.4
1.3
0.38
1.05
u/ml
—
9
65
10
66
1.58
0.55
1.5
1.2
—
—
—
0
0
8
55
1.50
0.44
2.1
1.7
—
—
—
0
0
8
56
1.47
0.44
3.6
3.9
—
—
—
0
0
8
58
1.41
0.43
4.4
2.3
—
—
—
0
0
5
33
1.54
0.42
1.0
1.2
—
—
—
0
0
5
34
1.50
0.41
1.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
13
165
0.75
0.35
1.2
1.5
—
—
—
0
0
20
168
1.24
0.30
6.0
2.9
14.05
17.77
ng/l
0.36
13
72
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
6
49
1.24
0.20
3.8
3.6
5.09
4.56
pmol/l
—
6
44
13
151
0.84
0.17
2.5
1.9
—
—
—
0
0
7
87
0.79
0.15
1.3
1.5
—
—
—
0
0
69
669
1.12
0.13
3.1
2.8
2.86
2.80
mmol/l
0.17
60
636
33
310
1.10
0.12
2.7
2.5
—
—
—
0
0
7
81
0.85
0.07
1.3
1.4
—
—
—
0
0
7
81
0.85
0.07
1.3
1.4
—
—
—
0
0
7
81
0.85
0.07
1.3
1.4
—
—
—
0
0
30
286
1.07
0.07
2.7
2.3
—
—
—
0
0
64
630
1.05
0.03
2.6
2.7
1.43
1.23
mmol/l
0.89
57
605
16
166
0.96
0.00
1.5
1.5
—
—
—
0
0
17
176
0.96
0.00
2.5
2.0
—
—
—
0
0
67
664
1.03
0.00
2.9
2.7
1.28
1.42
mmol/l
2.25
59
632
67
668
1.01
0.00
3.1
2.8
4.58
4.58
mmol/l
0.00
60
638
11
113
0.97
0.00
1.4
1.4
—
—
—
0
0
15
145
1.04
0.00
1.9
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
41.00
—
0
6
6
66
0.90
0.00
4.3
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
99.38
—
0
8
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
0.00
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
0.00
—
0
7
0
5
0.00
0.00
0.0
3.2
—
97.60
—
0
5
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
15.24
—
0
5
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: Z21_PROBL_RELATED_EDUCATION_LITER – Problems related to education and literacy
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).