No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1220 |
4. Check minimum number of eventsNone |
1220 |
5. Include endpointsNone |
1220 |
6. Filter based on genotype QC (FinnGen only) |
1189 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D14
- Name in latin
- Neoplasma benignum laryngis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Larynx
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7637 | 2657 | 4895 |
| Only index persons | 6316 | 2327 | 3989 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.08 | 0.14 |
| Only index persons | 0.13 | 0.09 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 55.93 | 55.72 | 55.94 |
| Only index persons | 54.31 | 54.47 | 54.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1189 | 389 | 800 |
| Unadjusted period prevalence (%) | 0.29 | 0.14 | 0.37 |
| Median age at first event (years) | 56.64 | 52.63 | 58.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1220
- Matched controls
- 12200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
247.7
307.7
472
31
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
4503599627370496.0
307.7
1034
*
DQA10
NOMESCO Finland
Biopsy of larynx
119.8
307.7
217
22
UDQ12
NOMESCO Finland
Flexible laryngoscopy
16.1
307.7
373
324
UDQ22
NOMESCO Finland
Microlaryngoscopy
106.2
307.7
298
37
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
121.1
293.3
149
14
ZXC10
NOMESCO Finland
Use of laser
23.9
284.6
213
107
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
80.9
267.7
143
20
J38.3
ICD-10 Finland
Other diseases of vocal cords
34.8
237.8
153
50
J38.1
ICD-10 Finland
Polyp of vocal cord and larynx
53.5
217.5
125
26
J37.0
ICD-10 Finland
Chronic laryngitis
14.0
193.1
189
158
1420
FHL
Laryngomicroscopy
26.7
175.7
123
51
UDQ02
NOMESCO Finland
Direct laryngoscopy
32.1
145.2
95
32
UJC01
NOMESCO Finland
Scopy of lower throat
22.8
128.3
95
45
21210
ICD-8 Finland
Benign neoplasm of respiratory system, Larynx
+∞
126.3
119
*
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
233.9
124.3
126
6
2121A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Larynx
+∞
112.2
106
*
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
34.9
99.1
63
19
R49.0
ICD-10 Finland
Dysphonia
11.2
74.1
80
76
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
16.7
73.1
62
39
R49.08
ICD-10 Finland
Other specified dysphonia
10.2
69.6
80
83
8070/3-C32.0
ICD-O-3
Squamous cell carcinoma, NOS, of glottis
95.6
65.7
72
8
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
18.1
63.9
52
30
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
9.5
59.5
72
80
J38.2
ICD-10 Finland
Nodules of vocal cords
26.5
59.1
41
16
8070/3-C32.9
ICD-O-3
Squamous cell carcinoma, NOS, of larynx, NOS
106.9
56.4
61
6
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.2
52.9
155
410
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
52.8
433
2113
J38.7
ICD-10 Finland
Other diseases of larynx
17.4
50.7
42
25
UJC02
NOMESCO Finland
Rigid oesophagoscopy
15.2
49.6
44
30
C32.9
ICD-10 Finland
Malignant neoplasm: Larynx, unspecified
464.4
45.6
45
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.3
44.2
59
74
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.4
43.8
180
597
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
43.4
314
1421
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
12.8
42.8
42
34
R07.0
ICD-10 Finland
Pain in throat
4.3
42.2
115
287
R49.01
ICD-10 Finland
Functional dysphonia
5.8
41.7
78
141
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
9.7
40.0
47
50
WX734
NOMESCO Finland
JET-ventilation
54.2
39.8
47
9
A02BC05
ATC
esomeprazole; systemic
2.2
39.5
558
3363
R49.09
ICD-10 Finland
Unspecified dysphonia
11.4
39.0
41
37
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.9
38.7
121
334
C32.1
ICD-10 Finland
Malignant neoplasm: Supraglottis
87.0
38.0
42
5
B977, D141,
ICD-10 Finland
+∞
37.7
36
*
ZXE00
NOMESCO Finland
One hour or less
2.2
37.3
546
3317
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.4
36.5
48
59
DQB30
NOMESCO Finland
Laryngectomy
190.6
36.0
37
*
WX402
NOMESCO Finland
General anaesthesia
2.4
34.1
299
1462
C32.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of larynx
123.6
33.9
36
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
32.3
524
3262
DQE00
NOMESCO Finland
Implantation of prosthetic replacement for larynx
116.5
31.8
34
*
R13
ICD-10 Finland
Dysphagia
3.2
31.3
134
452
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.9
30.5
156
583
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.5
28.6
71
164
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
6.8
27.8
44
67
DQB70
NOMESCO Finland
Total excision of vocal cord
102.5
27.8
30
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
26.7
399
2374
GBB00
NOMESCO Finland
Tracheostomy
6.5
26.2
43
68
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.4
25.7
206
958
GB3AV, ,
NOMESCO Finland
88.6
23.7
26
*
A02BC02
ATC
pantoprazole; systemic
1.9
23.7
836
6494
H02AB06
ATC
prednisolone; systemic
1.8
23.4
611
4315
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
7.8
23.0
32
42
WF002
NOMESCO Finland
Radical radiotherapy
2.9
21.5
107
392
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
19.2
413
2711
R03BB04
ATC
tiotropium bromide; inhalant
2.2
18.7
176
870
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
17.6
451
3093
1430
FHL
Laryngoscopy (direct)
96.5
17.6
19
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.7
17.3
97
378
Z50.5
ICD-10 Finland
Speech therapy
6.2
16.9
29
48
UDC00
NOMESCO Finland
Ear microscopy
2.5
16.7
109
458
J39.2
ICD-10 Finland
Other diseases of pharynx
7.4
16.6
24
33
ZXD20
NOMESCO Finland
Day surgery
2.1
16.1
167
854
R03AC02
ATC
salbutamol; inhalant
1.6
15.9
619
4700
A07AA02
ATC
nystatin; oral
2.7
15.8
87
336
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.6
15.3
88
348
130
Kela drug reimbursment
Malignant tumour
2.2
15.2
145
718
N07BA03
ATC
varenicline; oral
3.0
14.6
67
235
R21
ICPC
Throat symptom/complaint
1.9
14.5
191
1063
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
14.5
194
1086
4509
FHL
Other measure in this category
151.8
14.5
15
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.9
14.5
67
236
J04.0
ICD-10 Finland
Acute laryngitis
3.8
14.4
44
119
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.6
14.3
86
347
A02BC01
ATC
omeprazole; systemic
1.7
14.3
337
2237
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.5
14.2
90
373
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
14.2
574
4358
J01DA01
ATC
[U] cefalexin
1.6
14.0
724
5817
UJF32
NOMESCO Finland
Coloscopy
1.7
13.9
326
2157
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
13.9
304
1975
A02BC03
ATC
lansoprazole; oral
1.7
13.8
356
2416
8070/3-C32.1
ICD-O-3
Squamous cell carcinoma, NOS, of supraglottis
141.5
13.5
14
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
13.4
400
2811
UJC12
NOMESCO Finland
Flexible oesophagoscopy
6.1
13.4
23
38
J01AA02
ATC
doxycycline; systemic
1.7
13.4
911
7783
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
5.2
13.2
27
53
ZXB10
NOMESCO Finland
Medial
11.1
13.0
24
22
DQE10
NOMESCO Finland
Injection of foreign material into vocal cord
19.3
12.9
19
10
R04.2
ICD-10 Finland
Haemoptysis
2.9
12.9
62
223
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
12.8
456
3336
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
12.7
582
4508
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
70.6
12.6
14
*
C14.1
ICD-10 Finland
Malignant neoplasm of laryngopharynx unspecified
+∞
12.5
12
*
R4130
NOMESCO Finland
Speech therapy
3.5
12.4
43
127
J02AC01
ATC
fluconazole; systemic
1.6
12.3
352
2440
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
4.2
12.3
32
77
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
5.9
12.3
22
38
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.7
12.0
63
238
R23
ICPC
Voice symptom/complaint
3.9
12.0
35
92
H02AB04
ATC
methylprednisolone; systemic
1.9
11.9
176
1014
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
11.8
211
1288
ENA10
NOMESCO Finland
Biopsy of pharynx
14.8
11.8
19
13
GBB13
NOMESCO Finland
Revision of tracheostomy
65.6
11.6
13
*
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
11.5
250
1611
50808
ICD-8 Finland
Other diseases of upper respiratory tract, Alii definiti
11.9
11.3
20
17
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.9
11.3
143
784
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
5.0
11.2
24
49
UGB02
NOMESCO Finland
Tracheoscopy
25.3
11.1
15
6
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
11.1
121
628
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
11.0
211
1314
R95
ICPC
Chron obstructive pulmonary disease
2.9
10.8
51
182
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
5.0
10.8
23
47
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
10.5
343
2440
D02.0
ICD-10 Finland
Carcinoma in situ: Larynx
+∞
10.4
10
*
C320, 8077, 2
ICD-O-3
+∞
10.4
10
*
D10.7
ICD-10 Finland
Benign neoplasm: Hypopharynx
19.0
10.3
15
8
4784A
ICD-9 Finland
Other diseases of upper respiratory tract, Polyp of vocal cord or larynx[POLYPUS PLICAE VOCALIS]
13.2
10.2
17
13
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
10.1
81
373
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
8.0
10.1
22
28
R01AD08
ATC
fluticasone; nasal
1.6
10.0
289
1993
ZXA05
NOMESCO Finland
Left side
1.6
10.0
293
2030
J01FA10
ATC
azithromycin; systemic
1.5
9.9
575
4596
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
5.2
9.9
20
39
4760A
ICD-9 Finland
Chronic laryngitis and laryngotracheitis, Chronic laryngitis
9.6
9.8
19
20
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
9.7
124
680
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
9.7
252
1693
DQW99
NOMESCO Finland
Other operation on larynx
55.4
9.7
11
*
N02AA05
ATC
oxycodone; systemic
1.6
9.6
227
1490
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
9.4
55
220
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.4
318
2271
8070/2-C32.0
ICD-O-3
Squamous cell carcinoma in situ, NOS, of glottis
+∞
9.4
9
*
H02AB07
ATC
prednisone; oral
1.7
9.4
166
1008
J01MA12
ATC
levofloxacin; systemic
1.6
9.4
237
1582
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
9.3
228
1509
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
9.6
9.3
18
19
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
3.4
9.2
32
95
J01DB01
ATC
cefalexin; oral
1.5
9.1
929
8234
N02AX02
ATC
tramadol; systemic, rectal
1.5
9.1
505
3980
ZXA10
NOMESCO Finland
Bilateral
1.6
9.1
210
1368
N05BA01
ATC
diazepam; systemic, rectal
1.8
9.1
156
938
R02
ICPC
Shortness of breath/dyspnoea
1.8
9.1
148
878
D10.5
ICD-10 Finland
Benign neoplasm: Other parts of oropharynx
15.7
9.0
14
9
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
10.1
9.0
17
17
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.1
8.9
86
428
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
6.9
8.9
21
31
C13.9
ICD-10 Finland
Malignant neoplasm: Hypopharynx, unspecified
50.4
8.7
10
*
J38.4
ICD-10 Finland
Oedema of larynx
9.1
8.5
17
19
R03BA05
ATC
fluticasone; inhalant
1.7
8.5
188
1210
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
2.6
8.5
49
195
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
8.4
213
1418
J01FA06
ATC
roxithromycin; oral
1.5
8.4
430
3324
C32.2
ICD-10 Finland
Malignant neoplasm: Subglottis
90.7
8.4
9
*
A02BA02
ATC
ranitidine; systemic
1.6
8.4
228
1545
DQB00
NOMESCO Finland
Excision of lesion of larynx
+∞
8.3
8
*
R49.03
ICD-10 Finland
Atrophic dysphonia
4.1
8.3
22
54
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
8.3
54
228
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
4.4
8.2
20
46
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
2.8
8.2
41
152
SPAT1301
SPAT
No procedures
1.5
8.0
335
2491
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
7.9
124
726
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
3.1
7.7
31
101
H03AA01
ATC
levothyroxine sodium; systemic
1.6
7.7
214
1456
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.5
7.7
26
76
ZX070
NOMESCO Finland
Intensity modified radiotherapy
3.1
7.5
30
98
N03AX16
ATC
[U] pregabalin
1.5
7.5
249
1763
J31.0
ICD-10 Finland
Chronic rhinitis
1.9
7.5
89
478
K08.3
ICD-10 Finland
Retained dental root
1.9
7.4
93
509
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.8
7.4
35
126
WX400
NOMESCO Finland
Inhalation anesthesy
2.4
7.3
48
203
C32
ICD-10 Finland
Malignant neoplasm of larynx
+∞
7.3
7
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
7.3
131
798
J45
ICD-10 Finland
Asthma
1.8
7.3
101
570
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
15.8
7.2
11
7
J01FA09
ATC
clarithromycin; systemic
1.5
7.2
306
2272
R53
ICD-10 Finland
Malaise and fatigue
1.5
7.2
258
1853
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
7.1
154
985
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
3.4
7.1
25
75
GD6AD
NOMESCO Finland
CT of chest and neck
12.1
7.1
12
10
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.9
7.0
31
107
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
10.1
7.0
13
13
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
7.0
160
1037
N05CF01
ATC
zopiclone; oral
1.4
7.0
359
2759
N06AX16
ATC
venlafaxine; oral
1.7
7.0
131
808
A01AB09
ATC
miconazole; local oral
1.9
7.0
93
519
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
6.9
126
770
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
6.9
93
520
Z72.0
ICD-10 Finland
Tobacco use
2.8
6.9
34
125
M02AA07
ATC
piroxicam; topical
1.4
6.9
387
3023
WX002
NOMESCO Finland
Sedation and analgesia
1.5
6.8
217
1518
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.8
1000
9171
R05
ICD-10 Finland
Cough
1.5
6.8
207
1435
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
6.8
313
2360
J01CA04
ATC
amoxicillin; systemic
1.4
6.7
883
7917
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.7
407
3218
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
22.6
6.7
9
*
J20
ICD-10 Finland
Acute bronchitis
1.8
6.6
105
618
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
10.1
6.5
12
12
ZXA00
NOMESCO Finland
Right side
1.4
6.5
297
2232
E0000UV, ,
ATC
1.4
6.4
409
3257
R03DC03
ATC
montelukast; oral
1.6
6.4
153
1005
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.3
191
1320
R01AD09
ATC
mometasone; nasal
1.4
6.3
433
3486
J05.1
ICD-10 Finland
Acute epiglottitis
11.1
6.3
11
10
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
6.3
719
6266
C13.1
ICD-10 Finland
Malignant neoplasm: Aryepiglottic fold, hypopharyngeal aspect
+∞
6.3
6
*
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
3.0
6.3
26
87
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.2
391
3102
SPAT1263
SPAT
Sampling
1.4
6.2
426
3432
WZC30
NOMESCO Finland
Teaching
1.6
6.1
167
1132
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
6.0
989
9108
UJD02
NOMESCO Finland
Gastroscopy
2.0
6.0
59
296
EBA10
NOMESCO Finland
Operative extraction of tooth
1.7
6.0
111
681
R03BA02
ATC
budesonide; inhalant
1.5
6.0
179
1234
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
260
1627
1.76
13.52
4.5
3.5
0.80
0.82
mmol/l
1.92
250
1524
674
5406
1.55
12.49
8.9
9.3
4.29
4.21
e9/l
0.36
599
4696
546
4212
1.54
11.87
4.9
5.2
34.87
35.08
g/l
0.34
506
3933
417
3039
1.57
11.67
3.6
3.4
35.25
92.65
e6/l
1.66
328
2373
608
4834
1.51
11.27
15.5
16.5
1.27
1.31
inr
0.64
198
1392
480
3644
1.52
11.00
3.6
3.3
—
—
—
0
0
858
7368
1.55
10.87
8.7
7.8
83.23
79.58
u/l
0.51
811
6915
458
3466
1.51
10.54
3.9
3.8
43.81
125.60
e6/l
2.11
347
2537
628
5090
1.48
10.21
6.6
6.6
12.44
12.06
umol/l
0.13
596
4836
304
2129
1.57
9.85
2.9
2.6
4.41
4.43
e6/l
0.01
268
1917
568
4537
1.47
9.80
6.4
6.2
26.39
26.98
%
0.56
534
4252
252
1700
1.61
9.54
2.1
1.9
—
—
—
0
0
557
4456
1.46
9.40
6.3
6.0
58.88
57.78
%
1.25
526
4179
556
4464
1.45
9.12
2.7
2.7
—
—
—
0
0
42
150
2.86
8.92
1.1
1.1
—
—
—
0
0
693
5827
1.44
8.69
5.0
5.2
6.66
6.82
mmol/l
1.45
674
5485
80
393
2.11
8.55
2.6
2.9
—
—
—
0
0
589
4833
1.42
8.31
7.1
7.2
1.21
1.21
mmol/l
0.27
490
4106
799
6939
1.44
8.12
4.8
4.0
13.61
12.65
mm/h
0.91
747
6374
778
6733
1.43
7.99
4.2
3.7
14.99
14.85
pmol/l
0.74
700
6033
723
6180
1.42
7.93
5.5
4.4
369.14
1452.07
e6/l
0.69
14
98
364
2766
1.45
7.68
3.4
3.3
0.31
0.52
e6/l
1.95
282
2127
624
5261
1.38
7.07
2.9
2.7
—
—
—
0
0
539
4449
1.38
6.90
5.8
6.4
1.20
1.21
mmol/l
0.34
502
4056
492
4004
1.38
6.86
2.1
2.0
95.17
93.22
pmol/l
0.40
265
2127
76
406
1.93
6.50
2.2
1.9
—
—
—
0
0
386
3041
1.39
6.45
2.8
2.6
56.48
85.24
u/l
0.56
357
2823
157
1058
1.56
5.84
4.6
3.7
—
—
—
0
0
318
2466
1.39
5.73
2.4
2.1
3.03
3.06
mg/l
0.08
284
2091
245
1816
1.44
5.71
2.8
3.2
2.46
2.45
mmol/l
0.72
214
1598
399
3217
1.36
5.63
3.3
3.5
2.35
2.35
mmol/l
0.14
354
2821
915
8356
1.38
5.49
5.2
4.4
2.07
2.12
mu/l
0.13
838
7549
145
978
1.55
5.37
2.9
2.3
168.90
142.86
ug/g
0.23
111
786
260
1969
1.41
5.35
4.1
4.0
305.09
356.52
ng/l
0.22
198
1626
318
2499
1.37
5.22
3.7
4.1
87.33
86.84
%
0.11
311
2448
67
375
1.83
5.02
2.3
1.8
—
—
—
0
0
46
231
2.03
4.75
1.5
1.5
—
—
—
0
0
44
218
2.06
4.71
1.3
1.2
—
—
—
0
0
1002
9365
1.39
4.63
20.4
15.8
24.79
26.42
mg/l
0.92
873
7532
221
1666
1.40
4.63
1.4
1.4
2.78
2.60
g/l
0.30
148
1027
39
186
2.13
4.61
1.1
1.2
—
36.00
—
0
5
165
1189
1.45
4.44
2.1
2.6
1.84
1.79
%
0.27
153
1073
298
2371
1.34
4.44
2.4
2.5
—
—
—
0
0
224
1708
1.38
4.37
2.8
2.9
1.08
0.95
e6/l
0.20
125
1007
25
103
2.46
4.15
1.9
1.3
—
—
—
0
0
95
619
1.58
4.12
6.5
8.7
25.56
24.77
mmol/l
1.36
95
614
184
1372
1.40
4.10
2.4
2.6
20.96
23.19
%
1.22
162
1184
102
677
1.55
4.09
5.5
3.7
1.95
1.83
mmol/l
0.12
85
507
193
1454
1.39
4.04
2.3
2.5
2.36
2.27
g/l
1.31
187
1357
211
1622
1.36
3.90
3.2
3.1
1.80
1.42
e6/l
0.27
113
927
130
918
1.47
3.89
2.9
2.5
5.08
7.18
ug/l
1.44
119
810
108
738
1.51
3.80
2.1
2.7
10.11
10.89
g/l
0.95
101
675
204
1570
1.36
3.74
2.3
2.6
11.82
13.03
umol/l
1.54
195
1475
153
1124
1.41
3.71
2.5
2.9
11.53
8.93
umol/l
0.26
134
1002
181
1369
1.38
3.70
5.5
6.1
1.06
1.04
mmol/l
0.36
169
1264
449
3851
1.26
3.68
3.0
2.7
154.70
155.88
ug/l
0.02
425
3526
362
3027
1.28
3.65
2.4
2.2
202.59
244.75
u/l
0.56
346
2847
258
2065
1.32
3.63
1.7
1.7
0.94
1.30
mg/l
3.11
205
1609
1030
9761
1.35
3.61
21.8
18.4
139.48
139.68
mmol/l
1.77
1014
9506
1047
9965
1.36
3.42
12.2
10.7
27.46
27.41
u/l
0.03
1019
9597
165
1246
1.37
3.41
1.7
1.4
—
—
—
0
0
362
3055
1.26
3.34
3.3
3.1
1129.23
1685.66
ng/l
3.00
315
2610
423
3635
1.25
3.34
2.2
2.2
75.19
76.30
nmol/l
0.32
388
3210
1029
9786
1.33
3.24
22.1
18.6
3.99
4.00
mmol/l
0.19
1013
9521
201
1578
1.33
3.22
1.8
2.1
29.59
30.00
s
0.50
195
1526
521
4596
1.23
3.20
3.8
3.6
0.00
0.00
estimate
0.50
105
822
159
1208
1.36
3.17
2.1
1.8
—
—
—
0
0
34
179
1.93
3.17
3.5
3.1
4.38
4.45
e9/l
0.05
34
179
514
4532
1.23
3.16
4.7
4.8
0.00
0.00
estimate
-0.00
108
865
236
1902
1.30
3.13
1.7
1.8
1260.97
1157.26
nmol/l
0.86
187
1411
159
1211
1.36
3.12
2.2
1.9
—
—
—
0
0
299
2485
1.27
3.11
4.3
3.9
0.00
0.00
estimate
0.69
103
828
186
1452
1.33
3.10
1.2
1.3
47.97
35.30
iu/ml
0.28
56
463
35
188
1.89
3.08
3.8
3.5
60.23
57.70
%
0.54
35
188
120
881
1.40
2.95
3.2
3.0
399.80
221.00
ng/l
0.46
108
798
514
4557
1.22
2.94
3.7
3.6
0.00
0.00
estimate
0.50
116
914
159
1224
1.34
2.92
5.5
8.2
5.14
5.13
kpa
0.04
154
1171
48
289
1.69
2.92
4.8
3.1
25.55
24.72
mmol/l
0.65
48
284
159
1225
1.34
2.90
5.5
8.2
12.00
11.88
kpa
0.11
153
1175
939
8866
1.26
2.85
17.7
14.5
80.21
78.81
ml/min/173m2
1.20
819
7350
446
3909
1.22
2.83
4.8
3.8
42.55
58.11
ng/l
0.53
329
2866
158
1224
1.33
2.78
5.6
8.3
1.38
1.17
mmol/l
0.29
129
967
29
154
1.90
2.67
2.0
1.7
—
—
—
0
0
361
3112
1.23
2.67
3.7
3.5
30.82
34.75
u/l
1.48
342
2960
103
754
1.40
2.60
1.9
1.6
—
—
—
0
0
43
261
1.67
2.57
1.8
1.8
—
—
—
0
0
85
605
1.44
2.51
1.6
1.4
—
—
—
0
0
32
181
1.79
2.45
1.9
1.6
—
—
—
0
0
65
443
1.49
2.40
1.8
2.0
2.83
2.00
ug/l
0.25
59
396
9
27
3.35
2.39
1.4
1.0
—
—
—
0
0
5
8
6.27
2.37
1.4
1.1
—
—
—
0
0
103
767
1.37
2.37
3.2
2.8
80.68
65.69
ml/min/173m2
0.68
50
316
23
119
1.95
2.31
2.2
1.8
—
—
—
0
0
25
134
1.88
2.28
4.1
2.3
384.07
7095.94
u/l
—
9
43
173
1400
1.27
2.23
1.2
1.2
16.17
10.82
u/ml
0.27
56
513
42
265
1.61
2.20
1.2
1.6
—
—
—
0
0
664
6140
1.18
2.16
3.8
3.3
64.60
55.37
u/l
0.72
618
5710
216
1807
1.24
2.10
1.3
1.2
1.23
1.38
u/ml
0.14
64
483
124
970
1.31
2.08
3.4
3.9
1.86
1.97
mmol/l
0.11
108
793
14
62
2.27
2.08
1.1
1.3
—
—
—
0
0
309
2684
1.20
2.06
3.1
2.9
4775.86
5969.26
umol/l
0.18
268
2334
87
648
1.37
2.03
2.0
1.6
—
—
—
0
0
39
249
1.58
1.97
1.9
1.8
—
—
—
0
0
17
84
2.04
1.96
2.1
1.7
—
—
—
0
0
67
483
1.41
1.90
1.5
1.9
1.71
1.51
g/l
0.94
57
427
35
220
1.61
1.89
3.6
2.7
15.49
16.01
%
0.21
16
117
41
268
1.55
1.89
1.1
1.2
—
—
—
0
0
27
159
1.71
1.86
1.7
1.5
—
—
—
0
0
54
376
1.46
1.85
1.0
1.1
—
—
—
0
0
1070
10377
1.25
1.84
28.4
22.8
7.06
6.82
e9/l
1.97
1048
10058
1069
10367
1.25
1.84
28.3
23.0
40.04
40.37
%
0.88
1007
9654
122
971
1.28
1.82
3.2
3.9
5.86
5.86
kpa
0.00
116
943
18
94
1.93
1.80
1.9
1.9
—
—
—
0
0
1069
10373
1.25
1.78
28.5
22.8
245.96
241.85
e9/l
1.13
1050
10086
20
109
1.85
1.78
7.0
4.4
—
—
—
0
0
1069
10377
1.24
1.75
28.4
22.8
4.47
4.51
e12/l
1.45
1046
10058
1069
10379
1.24
1.73
28.7
22.9
134.98
136.39
g/l
2.11
1057
10203
25
148
1.70
1.71
1.1
1.3
—
—
—
0
0
29
179
1.64
1.70
2.0
1.9
—
—
—
0
0
120
964
1.27
1.68
2.8
2.3
0.20
0.21
g/l
0.97
115
896
41
277
1.50
1.66
2.0
2.4
105.95
99.77
ug/min
0.04
21
167
24
142
1.70
1.65
2.0
1.6
—
—
—
0
0
953
9165
1.18
1.64
5.2
4.7
6.05
6.05
mmol/l
0.05
868
8287
10
41
2.45
1.64
1.0
1.3
191.70
184.85
mmol/24h
—
10
41
40
270
1.50
1.63
1.1
1.2
—
—
—
0
0
10
43
2.34
1.59
3.4
4.0
—
—
—
0
0
120
973
1.26
1.57
7.4
7.8
9.54
10.28
mmol/l
0.57
114
929
838
7998
1.15
1.52
20.9
18.6
15.17
15.11
%
0.11
830
7854
0
44
0.00
1.51
0.0
2.2
—
50.88
—
0
36
388
3519
1.15
1.49
4.1
3.8
—
—
—
0
0
19
109
1.75
1.47
1.2
1.9
—
—
—
0
0
25
156
1.62
1.44
2.3
1.8
4.83
5.16
mmol/24h
0.16
25
137
912
8784
1.15
1.36
6.6
6.0
40.17
40.41
mmol/mol
0.37
844
8075
97
782
1.26
1.36
4.7
3.9
1.21
1.22
mmol/l
0.88
90
681
23
143
1.62
1.36
1.8
1.5
—
—
—
0
0
54
402
1.36
1.34
2.6
2.5
—
—
—
0
0
54
402
1.36
1.34
2.6
2.5
6.99
7.29
g/l
0.81
48
363
54
402
1.36
1.34
2.6
2.5
3.58
3.70
g/l
0.27
48
363
19
114
1.68
1.28
1.1
1.1
0.45
2.41
u/ml
—
8
67
51
380
1.36
1.27
2.6
2.5
2.71
2.96
g/l
1.23
45
341
27
178
1.53
1.27
1.6
1.8
—
—
—
0
0
27
178
1.53
1.27
1.6
1.8
—
—
—
0
0
6
25
2.41
1.24
2.8
3.0
—
—
—
0
0
50
373
1.36
1.24
2.6
2.6
10.00
10.82
g/l
0.66
44
333
87
702
1.26
1.23
3.0
3.9
83.58
93.73
ng/l
0.58
77
616
5
19
2.64
1.21
1.0
1.2
—
—
—
0
0
26
172
1.52
1.21
1.2
1.1
—
—
—
0
0
111
928
1.22
1.15
2.3
2.5
29.71
36.71
u/l
0.69
82
794
343
3138
1.13
1.13
4.0
3.2
7.31
7.88
mmol/l
1.71
291
2595
14
80
1.76
1.13
1.4
1.4
—
—
—
0
0
17
103
1.66
1.13
1.2
2.0
—
—
—
0
0
31
219
1.43
1.07
1.3
1.2
1.84
5.82
u/ml
—
5
30
13
74
1.76
1.07
1.2
1.6
75.62
84.07
umol/l
0.91
13
74
5
22
2.28
1.03
1.4
1.5
—
—
—
0
0
44
333
1.33
1.03
2.7
3.7
52.41
76.39
mg/l
0.60
32
272
44
333
1.33
1.03
2.7
3.7
27.57
46.88
mg/l
1.25
33
273
75
612
1.24
1.00
2.3
2.5
16.62
23.61
au/ml
—
6
44
0
31
0.00
0.96
0.0
3.9
—
71.81
—
0
26
502
4733
1.10
0.94
5.1
4.9
3.25
3.71
ug/l
0.17
449
4217
39
295
1.33
0.93
1.6
1.7
—
—
—
0
0
13
78
1.67
0.91
1.5
1.1
—
—
—
0
0
6
28
2.15
0.91
1.8
2.2
—
—
—
0
0
19
126
1.52
0.91
1.8
1.7
—
—
—
0
0
19
126
1.52
0.91
1.8
1.7
—
—
—
0
0
8
44
1.82
0.86
1.0
1.1
520.77
250.04
iu/ml
—
8
44
323
2991
1.11
0.86
3.5
3.3
258.43
283.94
mg/l
0.04
223
1975
57
462
1.25
0.83
2.9
3.4
4.33
4.52
pmol/l
0.73
52
402
18
121
1.49
0.83
1.5
1.5
—
—
—
0
0
137
1206
1.15
0.83
10.6
7.7
—
—
—
0
0
132
1160
1.15
0.82
2.0
1.9
1.51
1.55
%
0.22
116
992
6
34
1.77
0.76
2.5
2.2
11.25
263.71
ug/l
—
6
28
9
53
1.70
0.75
2.1
1.4
—
—
—
0
0
14
91
1.54
0.75
1.1
1.3
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
9
54
1.67
0.74
2.8
1.6
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
5
25
2.00
0.72
1.0
1.1
—
—
—
0
0
7
39
1.80
0.72
1.4
2.8
170.71
211.38
u/l
—
7
39
13
84
1.55
0.72
1.6
1.4
191.82
156.96
pmol/l
1.00
13
84
105
1197
0.87
0.72
5.0
4.6
31.44
31.64
%
0.07
78
794
35
273
1.29
0.72
1.8
1.6
0.07
22.31
iu/ml
—
7
54
71
601
1.19
0.71
2.1
1.8
—
—
—
0
0
965
9449
1.10
0.70
5.4
5.1
2.67
2.69
mmol/l
0.18
892
8627
940
9196
1.10
0.68
4.7
4.5
1.36
1.40
mmol/l
2.18
870
8400
5
27
1.86
0.68
1.2
1.1
—
—
—
0
0
5
27
1.86
0.68
1.2
1.2
—
—
—
0
0
5
27
1.86
0.68
1.2
1.8
—
—
—
0
0
11
69
1.60
0.68
1.2
1.0
0.32
0.51
u/ml
—
6
28
17
119
1.43
0.67
1.5
1.5
—
—
—
0
0
336
3158
1.09
0.65
4.2
3.9
9.24
9.14
mg/mmol
0.02
229
2044
97
850
1.15
0.65
2.2
2.8
66.37
66.35
g/l
0.01
88
774
7
44
1.59
0.65
2.6
1.7
—
—
—
0
0
10
62
1.62
0.65
1.3
1.4
—
—
—
0
0
10
62
1.62
0.65
1.3
1.4
—
—
—
0
0
92
804
1.16
0.64
2.5
3.2
4.59
4.56
kpa
0.05
86
778
17
121
1.41
0.62
1.5
1.5
—
—
—
0
0
23
173
1.34
0.62
1.1
1.1
198.93
289.18
u/ml
1.35
15
100
63
737
0.85
0.62
1.9
1.8
—
—
—
0
0
24
182
1.33
0.61
1.1
1.1
—
—
—
0
0
8
52
1.54
0.59
1.3
1.3
—
—
—
0
0
48
400
1.21
0.59
1.4
1.3
—
—
—
0
0
28
219
1.29
0.59
3.2
3.1
0.75
0.88
nmol/l
1.11
21
172
8
53
1.51
0.58
1.3
1.9
—
—
—
0
0
8
53
1.51
0.58
1.3
1.9
—
—
—
0
0
7
114
0.61
0.58
1.1
2.0
—
1552.00
—
0
5
945
9271
1.09
0.57
4.8
4.6
4.52
4.54
mmol/l
0.26
882
8529
59
503
1.18
0.57
1.2
1.2
46.16
140.61
iu/ml
3.33
19
195
8
54
1.48
0.57
3.0
1.6
—
—
—
0
0
8
54
1.48
0.57
4.1
2.3
—
—
—
0
0
8
54
1.48
0.57
1.4
1.3
145.25
459.04
u/l
—
8
49
10
149
0.67
0.56
1.3
1.5
—
—
—
0
0
9
63
1.43
0.52
1.2
1.2
0.50
1.99
u/ml
—
9
40
6
40
1.50
0.51
1.2
1.3
—
—
—
0
0
35
288
1.22
0.50
1.7
1.5
254.50
277.48
ug/g
0.25
21
166
46
390
1.19
0.49
3.3
3.7
1.34
1.42
mmol/l
0.33
46
385
39
326
1.20
0.49
3.0
2.5
38.85
37.62
g/l
0.64
33
287
907
8906
1.07
0.48
4.3
4.1
1.42
1.32
mmol/l
2.95
836
8081
223
2090
1.08
0.48
1.7
1.7
54144080.24
34151032.50
pmol/l
0.14
181
1713
7
46
1.52
0.48
1.3
1.3
—
—
—
0
0
13
93
1.40
0.48
1.2
1.7
—
—
—
0
0
13
93
1.40
0.48
1.2
1.7
—
—
—
0
0
13
93
1.40
0.48
1.2
1.7
—
—
—
0
0
115
1046
1.11
0.47
3.4
4.3
12.88
25.67
ug/l
0.54
95
877
41
349
1.18
0.44
3.0
2.6
1.01
1.35
g/l
0.24
34
308
25
202
1.24
0.43
6.9
7.0
112.00
921.00
iu/ml
—
5
35
104
946
1.11
0.43
2.3
2.3
11.62
13.16
nmol/l
1.33
91
842
250
2364
1.07
0.43
1.7
1.6
19.06
20.04
nmol/l
0.50
223
2008
9
130
0.69
0.43
1.0
1.0
—
—
—
0
0
28
230
1.22
0.42
1.3
1.5
34.99
26.72
iu/l
0.58
21
201
8
56
1.43
0.42
1.4
1.6
—
—
—
0
0
16
122
1.32
0.42
1.5
1.5
—
—
—
0
0
16
122
1.32
0.42
1.5
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
28.63
—
0
10
266
2527
1.07
0.41
1.6
1.7
1.41
1.41
mmol/l
0.03
217
2101
31
259
1.20
0.41
2.5
2.0
9.16
11.72
mg/l
1.19
31
238
16
123
1.30
0.40
1.5
1.5
—
—
—
0
0
8
61
1.31
0.39
1.4
1.2
—
—
—
0
0
9
66
1.37
0.38
2.7
1.5
—
—
—
0
0
26
215
1.21
0.38
1.5
1.4
—
—
—
0
0
9
70
1.29
0.36
1.0
1.8
16.32
19.44
nmol/l
—
9
63
5
78
0.64
0.35
1.4
1.4
—
—
—
0
0
5
78
0.64
0.35
1.4
1.4
—
—
—
0
0
5
78
0.64
0.35
1.4
1.4
—
—
—
0
0
392
3785
1.05
0.35
4.8
4.3
24.02
21.34
%
2.72
178
1832
16
126
1.27
0.35
1.9
2.3
12.17
23.56
mg/l
—
6
29
6
44
1.37
0.34
1.2
1.0
—
—
—
0
0
36
312
1.16
0.33
1.8
1.8
4.83
3.22
mg/l
0.33
23
235
6
88
0.68
0.33
1.3
1.5
—
—
—
0
0
25
211
1.19
0.31
3.8
3.8
45.77
1431.72
u/ml
0.64
20
199
73
668
1.10
0.30
2.2
1.9
—
—
—
0
0
25
212
1.18
0.30
3.2
3.6
28.85
28.10
mg/l
0.03
17
132
212
2023
1.06
0.30
4.9
4.0
1.01
1.02
kg/l
1.10
30
283
11
84
1.31
0.30
1.1
1.1
—
—
—
0
0
36
316
1.14
0.29
1.2
1.3
—
—
—
0
0
264
2745
0.95
0.29
2.9
3.1
0.70
0.76
ug/l
0.82
171
1815
27
232
1.17
0.28
1.3
1.5
10.52
7.79
u/l
0.38
21
191
8
62
1.29
0.28
1.1
1.7
—
—
—
0
0
8
62
1.29
0.28
1.1
1.7
—
—
—
0
0
79
847
0.93
0.24
1.4
1.4
—
—
—
0
0
15
179
0.84
0.23
1.1
1.4
—
—
—
0
0
12
97
1.24
0.23
1.1
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
41
371
1.11
0.22
2.8
2.5
0.30
0.35
u/ml
0.43
24
208
24
210
1.15
0.22
1.9
2.0
—
—
—
0
0
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
7.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
5
43
1.16
0.21
2.6
2.4
79.00
100.07
%
—
5
43
30
268
1.12
0.21
1.3
1.6
—
—
—
0
0
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
6
48
1.25
0.20
1.2
1.1
—
—
—
0
0
30
269
1.12
0.20
1.3
1.4
—
—
—
0
0
19
165
1.15
0.19
1.5
1.4
—
—
—
0
0
22
248
0.89
0.18
1.6
1.6
8771.47
13761.99
e6/l
0.34
15
184
11
91
1.21
0.17
1.0
1.2
1.24
1.55
nmol/l
0.94
11
83
24
214
1.12
0.17
1.2
1.1
—
—
—
0
0
29
262
1.11
0.17
2.0
2.0
—
—
—
0
0
7
63
1.11
0.17
1.1
1.6
—
—
—
0
0
5
67
0.75
0.17
1.0
1.4
—
290.00
—
0
5
18
203
0.89
0.15
1.6
1.4
11.31
49.35
e6/l
0.69
13
161
18
203
0.89
0.15
1.7
1.5
2815.00
686.78
e6/l
0.65
13
167
9
83
1.08
0.14
1.0
1.0
—
—
—
0
0
7
90
0.78
0.14
1.1
1.0
—
—
—
0
0
13
113
1.15
0.13
3.5
2.7
—
—
—
0
0
11
94
1.17
0.13
1.1
1.1
—
—
—
0
0
12
104
1.16
0.12
1.1
1.1
—
—
—
0
0
20
181
1.11
0.12
1.3
1.3
285.80
229.94
miu/ml
—
5
80
17
155
1.10
0.09
1.0
1.1
9.00
71.41
iu/ml
—
5
32
5
61
0.82
0.08
10.2
18.0
1465.80
1521.25
nmol/l
—
5
61
5
64
0.78
0.08
1.0
1.3
—
69.00
—
0
10
7
66
1.06
0.08
1.0
1.0
—
—
—
0
0
7
68
1.03
0.08
1.0
1.2
—
—
—
0
0
7
68
1.03
0.08
1.0
1.2
—
—
—
0
0
6
70
0.86
0.07
1.7
1.7
—
—
—
0
0
9
87
1.03
0.07
2.3
2.3
—
—
—
0
0
29
276
1.05
0.06
1.4
1.9
—
—
—
0
0
14
129
1.09
0.05
1.4
1.2
2.25
5.81
u/ml
—
8
57
21
198
1.06
0.05
2.2
1.7
5.67
5.22
iu/l
—
9
58
30
287
1.05
0.05
1.6
1.7
—
—
—
0
0
24
229
1.05
0.04
1.4
1.4
—
—
—
0
0
24
229
1.05
0.04
1.4
1.4
—
—
—
0
0
19
180
1.06
0.04
1.1
1.2
102.55
41.88
u/l
0.54
12
155
21
219
0.96
0.03
1.9
1.5
—
—
—
0
0
26
251
1.04
0.02
1.3
1.3
—
—
—
0
0
12
128
0.94
0.02
1.2
1.1
—
—
—
0
0
21
202
1.04
0.02
3.7
3.4
7.55
7.61
mmol/l
0.04
21
197
16
153
1.05
0.01
1.3
1.5
—
—
—
0
0
10
104
0.96
0.00
1.4
1.3
7.61
7.70
mmol/l
—
10
88
10
102
0.98
0.00
3.6
2.5
—
—
—
0
0
13
128
1.02
0.00
1.2
1.1
—
—
—
0
0
21
213
0.99
0.00
3.7
3.3
1.38
1.53
mmol/l
0.58
21
207
22
217
1.01
0.00
1.3
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.8
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
9
92
0.98
0.00
1.6
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
65
0.92
-0.00
2.2
1.6
—
—
—
0
0
5
54
0.93
-0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.4
1.4
—
—
—
0
0
7
73
0.96
-0.00
1.0
1.1
—
—
—
0
0
7
70
1.00
-0.00
1.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.6
4.12
7.60
u/l
—
6
48
5
56
0.89
-0.00
2.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_LARYNX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LARYNX | 1.44 [1.24, 1.67] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.792 |
During the follow-up period (1.1.1998 — 31.12.2019), 365 out of 1646 females with CD2_BENIGN_LARYNX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LARYNX | 1.766 [1.57, 1.99] | < 0.001 |
| Birth year | 0.985 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 973 out of 3146 males with CD2_BENIGN_LARYNX died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_LARYNX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.172% | 0.328% |
| 5 | 1.02% | 1.903% |
| 10 | 2.305% | 4.549% |
| 15 | 4.399% | 8.697% |
| 20 | 7.596% | 14.442% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_LARYNX – Benign neoplasm: Larynx
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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