No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1032 |
4. Check minimum number of eventsNone |
1032 |
5. Include endpointsNone |
1032 |
6. Filter based on genotype QC (FinnGen only) |
1009 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
Oral leukoplakia, including avohilmo
based on the number of shared cases.
Similar with more cases:
- Oral leukoplakia and other epithelial disorders of tongue and oral cavity , including avohilmo
- Other diseases of lip and oral mucosa
- Diseases of oral cavity, salivary glands and jaws
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5452 | 2705 | 2719 |
| Only index persons | 5235 | 2615 | 2620 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | 0.08 |
| Only index persons | 0.10 | 0.10 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 57.42 | 59.83 | 55.09 |
| Only index persons | 57.24 | 59.67 | 54.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1009 | 521 | 488 |
| Unadjusted period prevalence (%) | 0.20 | 0.18 | 0.22 |
| Median age at first event (years) | 58.36 | 58.44 | 58.27 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1032
- Matched controls
- 10320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K13.21
ICD-10 Finland
Leukoplakia caused by tobacco
+∞
307.7
388
*
K13.20
ICD-10 Finland
Idiopathic leukoplakia
+∞
307.7
677
*
EKA10
NOMESCO Finland
iopsy of buccal mucosa
37.2
307.7
246
86
K13.29
ICD-10 Finland
Indefinite leukoplakia
71.2
307.7
206
36
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
66.2
307.7
318
69
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
21.5
269.3
214
124
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
18.0
199.3
170
112
ECA20
NOMESCO Finland
Biopsy of gingiva
46.5
195.4
116
28
K13.78
ICD-10 Finland
Other change in the oral mucosa
18.0
159.4
134
85
SXA10
NOMESCO Finland
Oral mucosal sampling
27.9
159.3
110
44
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
76.1
155.9
84
12
SAA03
NOMESCO Finland
Extended examination of mouth
4.9
134.3
664
2798
EJ2S1
NOMESCO Finland
Photography of oral mucosa
38.0
114.2
71
20
EJB10
NOMESCO Finland
Excision of tumor or other lesion of apex or body of tongue
51.5
109.0
63
13
L43.8
ICD-10 Finland
Other lichen planus
14.3
104.6
98
75
SBA00
NOMESCO Finland
Microbiological examinations
12.0
104.3
110
102
EHA10
NOMESCO Finland
Biopsy of palate
32.4
98.3
64
21
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
39.4
91.0
56
15
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
14.0
88.8
84
65
WZC00
NOMESCO Finland
Treatment plan or consultation
3.4
82.9
550
2578
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
3.3
74.1
454
1997
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
6.2
67.9
125
225
A07AA02
ATC
nystatin; oral
5.4
67.1
145
303
SAA02
NOMESCO Finland
Basic examination of mouth
3.5
62.3
811
5290
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.9
61.6
118
220
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.8
57.7
564
3096
B37.08
ICD-10 Finland
Other candidal stomatitis
17.5
56.8
47
28
SAA04
NOMESCO Finland
Special examination of mouth
5.1
55.6
125
269
L43.9
ICD-10 Finland
Lichen planus, unspecified
8.0
51.5
72
96
TEA00
NOMESCO Finland
Biopsy of lip
14.0
50.5
47
35
K05.31
ICD-10 Finland
Periodontitis pronounced
3.4
49.8
215
744
SAA01
NOMESCO Finland
Simple examination of mouth
3.3
49.5
843
5965
WX110
NOMESCO Finland
Infiltration anesthesia
2.8
41.4
819
5936
SDA03
NOMESCO Finland
Periodontal treatment
2.4
40.5
500
2916
N07BA03
ATC
varenicline; oral
4.5
37.7
98
236
SDA04
NOMESCO Finland
Demanding periodontal treatment
2.4
37.0
363
1897
K13.2
ICD-10 Finland
Leukoplakia and other disturbances of oral epithelium, including tongue
47.3
34.0
41
9
K13.22
ICD-10 Finland
Erythroplakia of oral epithelium, including tongue
65.7
33.2
38
6
Z01.2
ICD-10 Finland
Dental examination
2.2
32.6
521
3290
Z72.0
ICD-10 Finland
Tobacco use
5.7
32.6
62
114
SFA10
NOMESCO Finland
One-surface restoration
2.2
32.2
631
4308
D20
ICPC
Mouth/tongue/lip symptom/complaint
4.3
31.9
86
213
A01AC01
ATC
triamcinolone; local oral
8.0
31.2
43
56
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
2.2
31.0
632
4354
K02.1
ICD-10 Finland
Caries of dentine
2.2
30.7
658
4615
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.7
29.6
180
741
K13.6
ICD-10 Finland
Irritative hyperplasia of oral mucosa
9.7
29.0
34
36
EBA00
NOMESCO Finland
Extraction of tooth
2.1
27.4
419
2556
A01AB09
ATC
miconazole; local oral
3.0
27.3
133
485
SFA20
NOMESCO Finland
Two-surface restoration
2.1
26.8
647
4638
WZA90
NOMESCO Finland
Other medical or dental certificate
2.2
25.8
288
1552
K05.30
ICD-10 Finland
Periodontitis complex
2.4
25.5
201
934
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
6.2
25.3
44
74
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
3.2
24.9
104
346
WX290
NOMESCO Finland
Other blockage of nerve
2.0
24.6
510
3428
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.2
24.5
260
1369
GBB00
NOMESCO Finland
Tracheostomy
7.4
23.9
35
49
SXC03
NOMESCO Finland
Other oral or dental procedure
7.4
23.4
34
47
8070/3-C02.1
ICD-O-3
Squamous cell carcinoma, NOS, of border of tongue
55.4
23.1
27
5
SFA30
NOMESCO Finland
Three-surface restoration
1.9
22.9
491
3311
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
85.4
22.8
25
*
K03.64
ICD-10 Finland
Dental calculus supragingival
2.0
22.3
342
2055
ZXC10
NOMESCO Finland
Use of laser
5.1
22.2
47
95
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
22.2
518
3578
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.8
22.2
35
53
D82
ICPC
Teeth/gum disease
1.9
21.7
403
2579
P17
ICPC
Tobacco abuse
7.1
21.3
32
46
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.9
21.1
385
2445
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.9
21.0
495
3413
EBA10
NOMESCO Finland
Operative extraction of tooth
2.5
20.8
141
607
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
2.0
20.5
286
1654
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.1
20.2
89
305
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
7.4
20.0
29
40
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.8
19.1
485
3388
K03.66
ICD-10 Finland
Tooth plaque
2.8
18.8
101
387
SBB10
NOMESCO Finland
Dental impressions
3.1
18.5
82
282
K02.0
ICD-10 Finland
Caries limited to enamel
2.2
18.5
187
956
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
18.2
514
3689
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
15.7
18.0
29
19
EJW99
NOMESCO Finland
Other operation on tongue or floor of mouth
183.0
17.6
18
*
EKB00
NOMESCO Finland
Excision of tumour or other lesion of cheek
15.9
17.6
28
18
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.4
17.2
132
601
EJB40
NOMESCO Finland
Hemiglossectomy
64.4
16.8
19
*
SXC05
NOMESCO Finland
Other oral or dental procedure
3.0
16.7
77
271
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.9
16.7
290
1789
ECA30
NOMESCO Finland
Excision of lesion of gingiva
7.1
16.6
25
36
K13.24
ICD-10 Finland
Gum problems in smokers
172.7
16.5
17
*
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.8
16.2
302
1902
D07AD01
ATC
clobetasol; topical
2.0
16.1
193
1048
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
13.8
16.0
27
20
SCA01
NOMESCO Finland
Preventive oral health care, short
1.8
15.9
291
1821
EJB30
NOMESCO Finland
Excision of tumor or other lesion of floor of the mouth
26.7
15.6
21
8
D07AC01
ATC
betamethasone; topical
1.7
15.3
384
2629
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.9
15.3
252
1523
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
14.2
15.1
25
18
B37.02
ICD-10 Finland
Chronic hyperplastic candidal stomatitis
81.3
14.6
16
*
K12.18
ICD-10 Finland
Other forms of stomatitis
15.6
14.4
23
15
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
14.3
251
1544
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
13.6
14.2
24
18
EDB00
NOMESCO Finland
Partial excision of mandible
43.1
14.1
17
*
J02AC01
ATC
fluconazole; systemic
1.7
14.1
383
2664
A01AB04
ATC
amphotericin B; local oral
2.9
14.0
67
241
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.7
14.0
44
122
B37.03
ICD-10 Finland
Chronic atrophic candida infection in the mouth
17.8
13.9
21
12
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.7
13.8
44
123
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
13.7
301
1974
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
76.2
13.6
15
*
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.8
13.5
264
1671
N05AH04
ATC
quetiapine; oral
1.9
13.5
189
1079
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
13.4
210
1242
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
4.9
13.4
29
60
SPAT1301
SPAT
No procedures
1.7
13.4
320
2146
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.6
13.0
43
123
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.1
13.0
55
184
JDB10
NOMESCO Finland
Percutaneous gastrostomy
5.7
12.9
24
43
EB1VA, ,
NOMESCO Finland
2.1
12.9
142
745
N05AA02
ATC
levomepromazine; systemic
3.0
12.6
55
188
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
10.2
12.5
24
24
S29
ICPC
Skin symptom/complaint other
1.8
12.0
194
1156
8070/3-C02.9
ICD-O-3
Squamous cell carcinoma, NOS, of tongue, NOS
47.2
11.9
14
*
S01.50
ICD-10 Finland
Open wound in oral cavity
9.8
11.8
23
24
L43.0
ICD-10 Finland
Hypertrophic lichen planus
9.8
11.8
23
24
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.9
11.7
157
881
EAA10
NOMESCO Finland
Excision of lesion of lip
5.6
11.7
22
40
KMAK, ,
NOMESCO Finland
1.6
11.6
506
3903
E0000UV, ,
ATC
1.6
11.4
409
3010
N05BA01
ATC
diazepam; systemic, rectal
1.9
11.4
149
828
N06AX11
ATC
mirtazapine; oral
1.6
11.4
353
2509
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.1
11.4
111
556
C04.0
ICD-10 Finland
Malignant neoplasm: Anterior floor of mouth
25.3
11.2
15
6
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.3
11.0
86
393
C02.10
ICD-10 Finland
Malignant neoplasm of tip of tongue
43.8
10.9
13
*
N05CD07
ATC
temazepam; oral
2.0
10.9
133
722
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
10.9
86
395
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.1
10.8
109
553
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.7
10.7
244
1601
J01FF01
ATC
clindamycin; systemic
1.6
10.6
284
1941
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
4.6
10.5
25
56
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
4.9
10.5
23
48
C02.2
ICD-10 Finland
Malignant neoplasm: Ventral surface of tongue
+∞
10.4
10
*
-1, ,
NOMESCO Finland
1.6
10.4
321
2270
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.2
10.3
91
438
L43.3
ICD-10 Finland
Subacute (active) lichen planus
19.0
10.3
15
8
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
2.0
10.1
109
566
K12.10
ICD-10 Finland
Stomatitis NOS
11.4
10.1
18
16
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
4.9
10.0
22
46
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.7
10.0
52
196
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
3.6
10.0
33
95
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.9
10.0
139
789
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
9.9
176
1075
L84
ICD-10 Finland
Corns and callosities
2.9
9.9
46
163
B37.01
ICD-10 Finland
Acute athrophy candidal stomatitis
16.9
9.9
15
9
K13.1
ICD-10 Finland
Cheek and lip biting
9.7
9.8
19
20
J01DB01
ATC
cefalexin; oral
1.7
9.7
830
7332
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
9.6
143
827
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.2
9.6
38
123
ZZA00
NOMESCO Finland
Split skin graft
3.1
9.5
39
129
N07BB01
ATC
disulfiram; oral
2.6
9.4
56
226
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.3
9.4
24
57
8070/3-C06.0
ICD-O-3
Squamous cell carcinoma, NOS, of cheeck mucosa
+∞
9.4
9
*
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
7.0
9.3
22
32
ECB00
NOMESCO Finland
Suture of gingiva
2.8
9.3
45
163
VALMI, ,
NOMESCO Finland
1.6
9.3
228
1518
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
9.3
300
2135
K14.9
ICD-10 Finland
Disease of tongue, unspecified
13.8
9.2
15
11
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.9
9.1
130
743
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
9.1
96
495
SFC92
NOMESCO Finland
Other complicated additional procedure necessary for restorative treatment
2.2
9.0
76
359
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
9.0
48
184
EMAK, ,
NOMESCO Finland
2.7
8.9
49
190
XQ802
NOMESCO Finland
Epicutan test
2.7
8.9
46
173
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.2
8.9
76
361
SPAT1310
SPAT
Counselling related to known health issue
1.6
8.8
304
2190
N05AB01
ATC
dixyrazine; systemic
4.7
8.8
20
43
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
8.7
178
1130
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.1
8.6
35
115
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.6
453
3567
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
8.6
661
5609
L17
ICPC
Foot/toe symptom/complaint
1.5
8.5
284
2031
K08.3
ICD-10 Finland
Retained dental root
2.1
8.5
86
437
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
3.9
8.5
24
62
SBA10
NOMESCO Finland
Measurement of salivary flow rate
4.4
8.4
21
49
8070/3-C03.1
ICD-O-3
Squamous cell carcinoma, NOS, of lower gum
90.8
8.4
9
*
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
2.5
8.3
52
215
E000001, ,
ATC
1.7
8.3
187
1216
R03AC02
ATC
salbutamol; inhalant
1.5
8.3
531
4330
WX199
NOMESCO Finland
Other local analgesia
2.8
8.1
39
141
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
3.5
8.1
27
78
EJ1S1
NOMESCO Finland
Photography of tongue
17.3
8.1
12
7
H02AB06
ATC
prednisolone; systemic
1.5
8.1
468
3737
SPAT1260
SPAT
Consultation of another employee
1.7
8.0
171
1095
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.0
329
2453
R03BB04
ATC
tiotropium bromide; inhalant
1.9
8.0
107
598
WYA10
NOMESCO Finland
Emergency care or similar visit
2.1
8.0
75
370
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
8.0
130
773
R95
ICPC
Chron obstructive pulmonary disease
2.9
8.0
36
126
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
7.9
51
214
SFA00
NOMESCO Finland
Small restoration
1.8
7.9
137
829
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.8
251
1774
L43
ICD-10 Finland
Lichen planus
4.2
7.8
20
48
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
6.4
7.7
19
30
EKC00
NOMESCO Finland
Suture of cheek
45.3
7.7
9
*
M54.5
ICD-10 Finland
Low back pain
1.5
7.7
349
2651
SPF20
NOMESCO Finland
Temporary relining of dentures
7.5
7.7
17
23
SPAT1240
SPAT
Therapeutic discussion
1.9
7.7
96
525
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
3.8
7.7
23
62
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
7.6
217
1491
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
7.6
67
322
AA1AD
NOMESCO Finland
CT of head and brain
1.5
7.6
264
1896
SGA01
NOMESCO Finland
Emergency treatment
1.7
7.5
156
991
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.4
7.5
53
232
EBB10
NOMESCO Finland
Insertion of dental implant
4.3
7.5
19
45
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
4.3
7.5
19
45
SPA02
NOMESCO Finland
Preparation for dental prosthetics
2.7
7.5
39
148
EB4VA, ,
NOMESCO Finland
1.8
7.4
104
591
N05BA04
ATC
oxazepam; oral
1.5
7.4
249
1777
SCF03
NOMESCO Finland
Preventive oral care by dental hygienist, extensive
4.1
7.4
20
50
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
7.4
77
396
N02BE01
ATC
paracetamol; systemic, rectal
1.7
7.4
899
8256
L03
ICPC
Low back symptom/complaint
1.5
7.3
261
1884
V03AA01, ,
ATC
3.5
7.3
24
69
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
9.4
7.3
14
15
Z04.3
ICD-10 Finland
Examination and observation following other accident
3.4
7.3
26
79
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
7.3
97
542
S10
ICPC
Boil/carbuncle
2.2
7.3
62
295
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
7.2
173
1140
D11
ICPC
Diarrhoea
1.8
7.2
108
627
EJB99
NOMESCO Finland
Other excision on tongue and floor of mouth
20.2
7.1
10
5
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
7.1
106
613
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.0
7.1
30
101
K14.61
ICD-10 Finland
Glossodynia
6.1
7.1
18
30
N03AE01
ATC
clonazepam; systemic
2.2
6.9
60
287
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
5.5
6.9
19
35
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.6
6.9
38
148
N06AB04
ATC
citalopram; systemic
1.6
6.9
203
1403
N05AA01
ATC
chlorpromazine; systemic, rectal
4.0
6.9
19
48
N06AX12
ATC
bupropion; oral
2.1
6.9
63
308
K08.80
ICD-10 Finland
Toothache NOS
1.9
6.9
85
463
SDA05
NOMESCO Finland
Very demanding periodontal treatment
2.1
6.9
68
343
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.8
252
1829
SPAT1263
SPAT
Sampling
1.4
6.8
385
3034
L28
ICPC
Limited function/disability (L)
1.6
6.8
166
1099
K04.1
ICD-10 Finland
Necrosis of pulp
1.8
6.8
107
630
K11.2
ICD-10 Finland
Sialoadenitis
2.7
6.8
36
138
P29
ICPC
Psychological sympt/compl other
2.1
6.8
60
290
L43.1
ICD-10 Finland
Bullous lichen planus
40.3
6.8
8
*
8070/3-C06.9
ICD-O-3
Squamous cell carcinoma, NOS, of mouth, NOS
40.3
6.8
8
*
K07.60
ICD-10 Finland
Snapping jaw
2.3
6.7
49
218
P76
ICPC
Depressive disorder
2.1
6.7
60
291
N02BF02
ATC
pregabalin; oral
2.1
6.7
61
298
K04.09
ICD-10 Finland
Pulpit UNS
2.3
6.7
47
206
M79.1
ICD-10 Finland
Myalgia
1.7
6.7
140
892
N03AX09
ATC
lamotrigine; oral
2.4
6.7
46
200
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
6.6
167
1113
K11.70
ICD-10 Finland
Hypoptyalism
7.9
6.6
14
18
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
6.6
122
752
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
6.6
101
590
Z01.9
ICD-10 Finland
Special examination, unspecified
2.0
6.6
67
342
N06AB03
ATC
fluoxetine; oral
1.7
6.5
125
777
N05CF01
ATC
zopiclone; oral
1.4
6.5
313
2390
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
2.5
6.5
38
153
D19
ICPC
Teeth/gum symptom/complaint
1.5
6.5
259
1908
SXA20
NOMESCO Finland
Local application of medicine to mouth
2.2
6.5
56
268
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.5
378
2990
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.5
388
3084
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
3.3
6.4
23
70
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
6.4
75
401
SAA03, ,
SPAT
70.3
6.4
7
*
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
70.3
6.4
7
*
EN1CD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
70.3
6.4
7
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
6.4
74
394
ECB20
NOMESCO Finland
Oral alveoplasty
4.1
6.4
17
42
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
6.3
74
396
N05AX12
ATC
aripiprazole; systemic
2.6
6.3
35
137
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.2
6.3
50
231
R02
ICPC
Shortness of breath/dyspnoea
1.7
6.3
123
769
K13.03
ICD-10 Finland
Keilit UNS
9.3
6.3
12
13
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
6.3
178
1219
SPE90
NOMESCO Finland
Other partial denture
3.0
6.3
26
87
C02.9
ICD-10 Finland
Malignant neoplasm: Tongue, unspecified
+∞
6.3
6
*
K03.0
ICD-10 Finland
Excessive attrition of teeth
2.6
6.2
35
138
A02BC01
ATC
omeprazole; systemic
1.5
6.2
256
1895
R13
ICD-10 Finland
Dysphagia
1.9
6.2
71
377
EBB15
NOMESCO Finland
Insertion of dental implant abutment
6.3
6.2
15
24
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.2
426
3461
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.1
6.1
59
295
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.1
489
4069
SPAT1058
SPAT
PEF monitoring instruction
1.9
6.1
81
453
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
10.1
6.0
11
11
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
6.0
128
818
R74
ICPC
Upper respiratory infection acute
1.5
6.0
261
1951
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
94
98
10.45
81.88
2.1
1.3
—
—
—
0
0
207
1079
2.15
19.56
4.9
4.6
31.07
32.01
%
0.54
138
733
635
5048
1.67
13.85
4.8
5.1
6.98
6.74
mmol/l
1.83
601
4749
535
4072
1.65
13.84
13.1
14.0
1.24
1.24
inr
0.00
93
1165
191
1087
1.93
13.79
7.4
7.1
—
—
—
0
0
383
2685
1.68
13.58
2.3
2.1
245.13
221.94
u/l
0.14
355
2532
251
1583
1.77
12.97
1.6
1.7
1139.67
1225.58
nmol/l
0.75
185
1200
886
7796
1.96
12.89
5.7
4.6
1.94
2.08
mu/l
0.41
785
7121
468
3517
1.61
12.21
2.0
2.0
94.03
95.50
pmol/l
0.25
233
1807
749
6344
1.66
11.57
5.0
4.1
12.83
12.32
mm/h
0.43
673
5860
508
3930
1.58
11.47
6.0
6.4
1.21
1.21
mmol/l
0.24
449
3590
75
325
2.41
10.84
1.8
1.8
—
—
—
0
0
70
297
2.46
10.59
1.5
1.7
—
—
—
0
0
781
6749
1.65
10.47
8.1
7.7
78.66
78.54
u/l
0.03
731
6352
485
3766
1.54
10.43
4.6
4.9
35.48
35.54
g/l
0.08
448
3517
538
4281
1.54
10.29
7.0
7.2
1.21
1.21
mmol/l
0.68
464
3659
681
5732
1.55
9.87
3.9
3.2
51.26
53.06
u/l
0.20
616
5348
749
6450
1.59
9.74
4.7
3.9
14.97
14.87
pmol/l
0.47
654
5858
568
4610
1.52
9.65
5.8
6.4
10.61
11.58
umol/l
1.19
534
4390
363
2736
1.50
8.49
2.8
2.6
56.72
89.69
u/l
0.58
333
2532
70
333
2.18
8.17
4.0
4.0
24.94
24.88
mmol/l
0.06
64
316
287
2073
1.53
8.15
2.5
2.3
—
—
—
0
0
494
3988
1.46
8.04
2.7
2.6
—
—
—
0
0
496
4047
1.43
7.41
7.1
5.9
57.85
57.01
%
0.82
458
3804
426
3386
1.44
7.32
3.6
3.6
29.70
49.48
ng/l
1.03
303
2418
956
8940
1.94
7.31
19.9
16.7
139.24
139.71
mmol/l
5.38
932
8716
922
8540
1.75
7.11
17.5
14.4
23.30
24.22
mg/l
0.37
777
6779
957
8971
1.92
6.98
19.8
16.8
4.00
3.98
mmol/l
1.63
930
8734
499
4108
1.42
6.93
7.5
6.2
27.37
27.71
%
0.29
464
3861
882
8092
1.62
6.86
6.7
5.9
41.16
40.06
mmol/mol
1.09
797
7505
435
3500
1.42
6.86
2.4
2.3
75.54
77.36
nmol/l
0.70
373
3122
583
4979
1.39
6.29
9.9
9.3
4.40
4.09
e9/l
2.12
522
4361
368
2921
1.40
6.08
3.1
3.6
2.36
2.36
mmol/l
0.15
313
2585
195
1388
1.50
5.73
1.9
1.9
—
—
—
0
0
634
5541
1.37
5.65
5.0
4.3
1424.00
2348.47
e6/l
—
8
83
32
130
2.51
5.41
5.5
5.4
383.60
371.66
umol/l
0.20
25
114
271
2075
1.42
5.40
2.2
2.1
2.87
3.11
mg/l
0.61
225
1769
154
1058
1.54
5.33
2.7
1.9
1.68
1.51
%
2.05
130
919
27
106
2.59
4.91
1.6
1.4
—
—
—
0
0
346
2800
1.35
4.85
3.8
3.2
7.12
7.62
mmol/l
1.35
282
2376
127
854
1.56
4.84
2.1
2.2
0.21
0.21
g/l
0.26
119
800
27
107
2.56
4.82
1.6
1.4
—
—
—
0
0
27
107
2.56
4.82
1.6
1.4
—
—
—
0
0
27
108
2.54
4.74
1.6
1.4
—
—
—
0
0
27
108
2.54
4.74
1.6
1.4
—
—
—
0
0
329
2656
1.35
4.65
3.5
3.3
230.52
246.48
mg/l
0.03
202
1704
965
9210
1.74
4.63
12.7
10.7
26.48
27.06
u/l
0.54
926
8892
234
1806
1.38
4.36
1.3
1.2
1.08
1.69
u/ml
0.87
66
495
143
1009
1.48
4.35
6.4
9.0
5.06
5.14
kpa
0.45
138
970
143
1009
1.48
4.35
6.4
9.0
11.63
12.19
kpa
0.79
137
973
142
1004
1.48
4.28
6.5
9.0
1.42
1.20
mmol/l
0.29
103
810
256
2011
1.36
4.26
1.7
1.5
18.47
20.75
nmol/l
1.94
213
1704
26
108
2.44
4.25
1.6
1.4
—
—
—
0
0
218
1670
1.39
4.24
4.1
3.9
1159.94
395.95
ng/l
0.38
167
1332
898
8469
1.46
4.11
5.2
4.7
6.08
5.98
mmol/l
0.98
804
7718
166
1222
1.43
4.05
2.4
2.4
2.31
2.32
g/l
0.04
156
1133
20
75
2.70
4.01
1.3
1.3
31.39
32.97
u/l
0.06
15
61
137
979
1.46
3.92
2.1
2.3
145.48
134.75
ug/g
0.10
106
786
339
2806
1.31
3.90
3.9
3.8
4.47
9.33
mg/mmol
3.76
197
1770
38
193
2.01
3.87
1.5
1.3
—
—
—
0
0
25
107
2.37
3.85
2.6
2.2
71.20
22.63
mg/l
—
5
26
986
9521
1.80
3.79
26.9
21.2
253.72
248.34
e9/l
1.67
960
9277
986
9526
1.79
3.71
26.9
21.1
4.45
4.51
e12/l
4.22
955
9259
986
9529
1.78
3.66
27.0
21.3
135.75
136.36
g/l
0.66
969
9385
985
9519
1.76
3.62
26.9
21.3
40.01
40.43
%
1.04
901
8909
80
519
1.59
3.59
4.0
3.5
1.10
1.79
mmol/l
0.98
65
395
44
242
1.85
3.57
1.5
1.4
—
—
—
0
0
14
46
3.07
3.54
1.8
1.2
—
—
—
0
0
14
46
3.07
3.54
1.8
1.2
—
—
—
0
0
92
619
1.53
3.53
1.6
1.6
—
—
—
0
0
188
1454
1.36
3.41
3.3
3.4
0.81
0.82
mmol/l
0.28
172
1369
83
551
1.55
3.39
4.0
3.5
5.29
5.16
kpa
0.72
75
535
876
8285
1.38
3.38
4.7
4.1
1.48
1.33
mmol/l
1.19
782
7585
205
1609
1.34
3.38
1.3
1.5
2.56
2.55
g/l
0.02
120
990
282
2322
1.30
3.29
2.4
2.7
2507.56
5560.54
umol/l
1.03
238
2037
130
952
1.42
3.27
2.2
2.6
1.83
1.83
%
0.00
108
858
173
1337
1.35
3.15
2.4
2.4
12.58
13.12
umol/l
0.49
162
1241
153
1166
1.37
3.05
2.4
2.5
21.03
23.07
%
1.12
118
999
98
693
1.46
2.99
2.6
2.9
193.74
202.77
ng/l
0.10
90
633
53
326
1.66
2.98
1.3
1.2
0.28
1.29
u/ml
—
6
24
77
521
1.52
2.92
1.5
1.5
—
—
—
0
0
104
757
1.42
2.73
2.3
2.5
5.19
7.00
ug/l
0.47
91
666
38
220
1.76
2.68
2.0
1.7
12375.68
15197.75
e6/l
0.28
25
165
9
24
3.77
2.67
1.4
1.8
—
—
—
0
0
917
8802
1.38
2.66
5.8
5.1
2.67
2.77
mmol/l
2.67
833
8108
228
1876
1.28
2.63
4.6
3.9
1.02
1.02
kg/l
0.08
30
251
83
590
1.44
2.49
2.1
1.8
—
—
—
0
0
39
233
1.70
2.48
1.2
1.2
—
—
—
0
0
74
515
1.47
2.48
1.2
1.2
287.24
142.40
iu/ml
1.32
28
209
6
12
5.02
2.40
1.0
1.1
—
—
—
0
0
33
190
1.76
2.40
1.4
1.4
13.10
8.86
u/l
0.59
25
152
895
8585
1.32
2.39
5.3
4.5
1.43
1.46
mmol/l
0.84
813
7899
147
1156
1.32
2.39
5.7
5.9
1.04
1.03
mmol/l
0.42
136
1068
125
960
1.34
2.39
4.8
4.3
223.14
253.43
u/l
2.07
115
906
158
1256
1.30
2.38
1.4
1.4
—
—
—
0
0
899
8639
1.32
2.29
5.4
4.6
4.59
4.67
mmol/l
1.45
820
8000
12
47
2.57
2.27
1.1
1.5
1.72
1.22
nmol/l
—
7
34
281
2414
1.23
2.19
1.9
1.7
1.49
1.40
mmol/l
0.84
245
2032
22
115
1.93
2.16
1.3
1.1
—
—
—
0
0
58
396
1.49
2.16
1.1
1.0
—
—
—
0
0
75
539
1.42
2.15
2.0
1.7
—
—
—
0
0
321
2800
1.21
2.14
4.0
3.3
49.25
32.72
u/l
0.46
303
2668
41
262
1.59
2.06
1.6
1.6
2.51
0.09
iu/ml
—
8
43
6
15
4.02
2.04
2.5
1.9
20.95
16.48
umol/l
—
6
15
10
39
2.58
1.94
1.0
3.2
675.50
1484.18
u/ml
—
10
39
65
465
1.42
1.94
4.2
3.2
4.48
4.55
pmol/l
0.18
56
406
11
45
2.46
1.93
1.3
1.3
—
—
—
0
0
20
106
1.90
1.91
1.7
1.6
65.36
61.66
%
0.19
14
74
20
107
1.89
1.87
1.7
2.2
570.67
2587.67
u/l
—
6
32
31
190
1.65
1.86
2.2
1.9
—
—
—
0
0
5
12
4.18
1.82
1.0
1.1
—
—
—
0
0
33
208
1.61
1.78
1.3
1.4
—
—
—
0
0
37
240
1.56
1.78
2.2
1.8
—
—
—
0
0
212
1807
1.22
1.77
1.7
1.7
453.19
35223914.86
pmol/l
1.91
165
1499
384
3460
1.17
1.72
2.9
2.7
134.66
142.68
ug/l
0.25
341
3177
99
777
1.30
1.68
2.6
2.1
390.11
371.51
nmol/l
0.37
93
721
10
40
2.51
1.67
1.8
1.2
—
—
—
0
0
10
40
2.51
1.67
1.8
1.2
—
—
—
0
0
6
19
3.17
1.66
1.5
2.6
—
—
—
0
0
292
2582
1.18
1.63
2.6
3.0
1051.14
1182.14
ng/l
0.40
246
2196
10
44
2.28
1.56
1.3
1.1
—
—
—
0
0
53
722
0.72
1.55
3.3
4.0
1.24
1.23
mmol/l
0.24
45
637
28
178
1.59
1.50
3.8
3.5
29.51
24.93
mg/l
0.18
14
109
9
37
2.44
1.48
4.1
3.0
42244.44
40046.08
ug/l
—
9
37
19
109
1.76
1.47
1.2
1.1
3.18
2.30
u/ml
—
7
62
57
758
0.74
1.45
1.7
1.8
—
—
—
0
0
31
204
1.54
1.44
1.5
1.7
5.45
5.21
iu/l
—
6
64
112
913
1.25
1.43
3.2
4.3
76.19
24.64
ug/l
0.36
92
756
9
39
2.32
1.43
2.0
2.5
—
—
—
0
0
36
246
1.48
1.41
1.4
1.4
235.87
276.93
ug/g
0.60
20
142
5
121
0.41
1.38
1.0
1.1
—
—
—
0
0
850
8225
1.19
1.34
14.3
13.4
82.12
80.17
ml/min/173m2
2.09
717
6809
219
1924
1.18
1.32
1.6
1.7
1.13
1.17
mg/l
0.10
162
1476
164
1405
1.20
1.31
1.3
1.3
13.38
10.70
u/ml
0.18
55
548
89
715
1.27
1.30
2.2
2.6
72.36
65.76
ml/min/173m2
0.85
43
289
27
177
1.54
1.30
2.5
3.1
0.78
0.89
nmol/l
0.58
19
140
40
286
1.41
1.27
1.7
1.9
—
—
—
0
0
69
539
1.30
1.26
1.8
1.6
—
—
—
0
0
234
2624
0.86
1.25
3.4
3.3
530.86
92.88
e6/l
0.43
195
2038
35
245
1.44
1.24
1.2
1.1
—
—
—
0
0
24
155
1.56
1.23
1.1
1.7
—
—
—
0
0
15
85
1.78
1.23
1.9
1.3
8017.25
120411.83
e6/l
—
8
63
8
37
2.17
1.21
1.3
2.1
79.11
56.01
ug/l
—
8
37
30
208
1.46
1.14
1.4
1.3
373.59
213.86
miu/ml
—
7
94
185
1627
1.17
1.11
2.9
3.1
2.45
2.45
mmol/l
0.53
163
1442
33
235
1.42
1.10
1.2
1.2
3.63
5.50
u/ml
—
6
35
7
32
2.20
1.08
1.1
2.9
—
74227.17
—
0
6
34
246
1.40
1.04
1.2
1.1
—
—
—
0
0
118
1005
1.20
1.04
1.9
1.8
—
—
—
0
0
40
299
1.35
1.02
5.1
2.9
—
—
—
0
0
82
677
1.23
0.99
4.1
3.9
74.02
85.66
ng/l
1.13
65
601
34
249
1.38
0.98
1.4
1.2
—
—
—
0
0
217
2405
0.88
0.97
3.4
3.2
0.39
0.50
e6/l
0.37
181
1836
0
31
0.00
0.96
0.0
1.1
—
77.40
—
0
5
84
698
1.22
0.96
2.8
2.3
11.81
13.34
nmol/l
1.04
70
633
168
1487
1.16
0.94
1.3
1.3
61.13
31.57
iu/ml
1.05
50
475
41
315
1.31
0.89
1.2
2.5
3.09
2.96
g/l
0.31
33
287
38
289
1.33
0.89
3.3
3.7
29.55
41.13
mg/l
0.52
31
234
38
289
1.33
0.89
3.3
3.7
43.68
73.30
mg/l
0.69
32
232
33
246
1.35
0.88
1.2
1.2
—
13.83
—
0
12
114
987
1.17
0.86
2.5
2.7
8.74
8.96
umol/l
0.03
95
874
33
248
1.34
0.84
1.2
1.6
—
—
—
0
0
123
1401
0.86
0.82
3.2
3.0
2.15
2.17
e6/l
0.01
77
768
8
47
1.71
0.80
4.1
3.4
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
18
123
1.47
0.78
1.2
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
13
83
1.57
0.75
2.4
2.3
—
—
—
0
0
209
2283
0.89
0.75
4.5
3.9
0.00
0.01
estimate
0.88
42
755
5
24
2.09
0.74
1.2
1.1
142.80
332.00
pmol/l
—
5
14
9
54
1.67
0.74
1.4
1.8
—
—
—
0
0
49
397
1.25
0.74
1.2
1.3
—
—
—
0
0
720
7408
0.91
0.74
20.2
17.4
15.80
15.03
%
2.10
707
7277
24
176
1.37
0.73
1.5
1.3
—
—
—
0
0
24
176
1.37
0.73
1.5
1.3
—
—
—
0
0
9
56
1.61
0.72
1.0
1.2
—
—
—
0
0
12
76
1.59
0.72
1.0
1.0
294.00
289.42
mg/l
—
7
66
162
1791
0.89
0.71
2.7
2.9
0.62
0.72
ug/l
1.49
97
1130
44
357
1.24
0.67
2.1
2.0
0.64
2.08
ug/l
1.01
38
321
17
119
1.44
0.67
1.1
1.7
—
—
—
0
0
20
145
1.39
0.66
1.8
1.7
—
—
—
0
0
20
145
1.39
0.66
1.8
1.7
—
—
—
0
0
42
340
1.25
0.66
1.2
2.4
7.46
7.37
g/l
0.09
34
312
42
340
1.25
0.66
1.2
2.4
—
—
—
0
0
42
340
1.25
0.66
1.2
2.4
3.76
3.59
g/l
0.39
34
312
113
1002
1.14
0.65
2.0
1.8
—
—
—
0
0
22
164
1.35
0.62
2.8
1.2
37.87
28.27
u/l
0.28
17
139
39
316
1.24
0.61
1.3
2.4
10.85
10.62
g/l
0.11
31
287
8
50
1.60
0.61
3.3
1.7
5.38
4.55
umol/l
—
8
31
8
50
1.60
0.61
3.0
1.5
6.88
6.16
u/l
—
8
43
0
20
0.00
0.60
0.0
1.3
—
7.71
—
0
20
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
36
290
1.25
0.60
1.2
2.7
0.57
1.18
g/l
0.59
27
261
79
903
0.86
0.59
3.6
3.3
—
—
—
0
0
12
81
1.49
0.57
2.3
1.6
—
—
—
0
0
12
81
1.49
0.57
2.3
1.6
—
—
—
0
0
12
81
1.49
0.57
2.3
1.6
—
—
—
0
0
91
806
1.14
0.56
4.0
3.5
1.12
2.05
mmol/l
1.16
79
665
10
65
1.54
0.55
1.0
1.1
—
—
—
0
0
10
65
1.54
0.55
1.0
1.1
—
—
—
0
0
12
171
0.70
0.55
3.6
3.3
3.82
4.32
e9/l
0.61
12
171
10
66
1.52
0.52
1.0
1.1
—
—
—
0
0
10
66
1.52
0.52
1.0
1.1
—
—
—
0
0
10
66
1.52
0.52
1.0
1.1
—
—
—
0
0
14
192
0.73
0.52
1.6
1.5
—
—
—
0
0
6
98
0.61
0.52
4.7
4.0
—
—
—
0
0
18
135
1.34
0.51
1.2
1.6
—
—
—
0
0
11
75
1.47
0.51
1.2
1.4
—
—
—
0
0
7
45
1.56
0.49
2.1
1.3
—
—
—
0
0
13
178
0.73
0.49
3.6
3.7
57.00
57.36
%
0.05
13
178
16
119
1.35
0.48
1.1
1.1
—
—
—
0
0
523
5063
1.07
0.47
2.8
2.7
—
—
—
0
0
322
3070
1.07
0.46
4.5
4.6
1.65
2.26
ug/l
2.24
280
2768
14
103
1.36
0.45
1.1
1.7
—
—
—
0
0
14
103
1.36
0.45
1.1
1.7
—
—
—
0
0
11
78
1.41
0.43
1.5
1.5
0.16
0.34
nmol/l
—
5
58
23
185
1.25
0.42
2.0
2.2
122.87
128.87
g/l
0.48
15
137
5
35
1.43
0.39
4.0
1.9
—
—
—
0
0
5
35
1.43
0.39
4.0
1.9
—
—
—
0
0
5
36
1.39
0.38
1.0
1.6
—
—
—
0
0
5
36
1.39
0.38
4.0
1.9
—
—
—
0
0
81
734
1.11
0.38
3.0
2.9
67.18
66.83
g/l
0.17
69
674
32
272
1.18
0.36
1.3
2.3
37.63
37.88
g/l
0.10
24
244
35
406
0.86
0.36
3.4
3.6
55.54
48.12
%
1.17
35
399
140
1497
0.93
0.36
2.9
2.8
0.86
1.06
e6/l
0.57
94
859
6
43
1.40
0.35
3.5
1.7
—
—
—
0
0
6
43
1.40
0.35
3.5
1.7
—
—
—
0
0
6
44
1.37
0.34
1.0
1.0
—
—
—
0
0
407
4198
0.95
0.34
3.8
3.6
0.00
0.00
estimate
0.50
49
826
6
45
1.34
0.33
1.5
1.3
—
—
—
0
0
6
45
1.34
0.33
1.5
1.3
—
—
—
0
0
14
177
0.79
0.33
1.2
1.2
—
—
—
0
0
34
391
0.87
0.32
1.3
2.1
44.58
39.30
u/l
0.74
29
343
236
2464
0.95
0.31
4.0
4.0
20.71
20.97
%
0.09
93
1110
7
99
0.71
0.30
1.1
2.0
—
—
—
0
0
7
55
1.27
0.30
1.3
1.2
16.29
11.42
u/l
—
7
48
15
121
1.24
0.28
1.2
1.7
—
—
—
0
0
10
129
0.77
0.28
1.1
1.8
—
—
—
0
0
12
94
1.28
0.28
2.3
1.8
—
—
—
0
0
27
233
1.16
0.27
1.6
2.2
75.11
85.67
ug/min
0.12
15
132
24
207
1.16
0.25
1.8
1.8
—
—
—
0
0
9
76
1.19
0.24
1.2
1.1
—
—
—
0
0
10
78
1.28
0.24
7.3
4.6
92.20
29.96
u/ml
—
5
25
50
456
1.10
0.24
9.0
11.5
24.19
24.51
mmol/l
0.38
50
450
11
88
1.25
0.22
2.4
1.8
—
—
—
0
0
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
318
3264
0.96
0.21
3.9
3.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
32.19
—
0
7
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
30
269
1.12
0.20
1.5
1.6
—
—
—
0
0
24
212
1.14
0.19
1.8
1.8
—
—
—
0
0
6
51
1.18
0.19
1.2
2.0
—
—
—
0
0
26
232
1.12
0.18
1.2
1.3
—
—
—
0
0
20
176
1.14
0.17
3.3
3.8
57.84
1624.75
u/ml
0.61
20
169
10
83
1.21
0.15
2.2
2.3
—
—
—
0
0
9
82
1.10
0.15
1.4
1.8
—
—
—
0
0
24
264
0.91
0.14
1.7
1.6
—
—
—
0
0
26
237
1.10
0.14
1.4
1.3
—
—
—
0
0
10
117
0.85
0.13
1.3
1.5
—
—
—
0
0
16
142
1.13
0.12
1.7
1.2
—
—
—
0
0
10
85
1.18
0.12
1.3
1.1
—
—
—
0
0
415
4200
0.98
0.10
5.1
4.9
0.00
0.00
estimate
-0.00
50
782
21
193
1.09
0.10
1.2
2.2
0.77
0.87
nmol/l
0.44
16
162
5
45
1.11
0.10
1.2
1.5
—
—
—
0
0
6
56
1.07
0.08
1.0
1.2
—
—
—
0
0
6
57
1.05
0.08
1.0
1.2
—
—
—
0
0
17
156
1.09
0.08
2.0
1.9
—
—
—
0
0
6
73
0.82
0.07
1.7
1.3
—
—
—
0
0
13
118
1.10
0.07
1.2
1.3
0.56
0.66
nmol/l
0.86
13
108
23
216
1.07
0.07
1.3
1.1
—
—
—
0
0
14
128
1.10
0.06
1.1
1.1
—
15.20
—
0
8
183
1803
1.02
0.06
2.6
2.6
5.26
5.43
e6/l
0.08
167
1637
421
4243
0.99
0.06
3.9
3.6
0.00
0.01
estimate
0.80
41
749
17
180
0.94
0.04
1.5
1.6
—
—
—
0
0
110
1086
1.01
0.03
1.5
1.4
—
—
—
0
0
85
837
1.02
0.03
2.2
2.4
72.28
33.54
u/l
0.63
72
715
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
28
286
0.98
0.00
2.4
2.6
0.35
0.35
u/ml
0.01
16
162
22
216
1.02
0.00
1.5
1.6
—
—
—
0
0
15
153
0.98
0.00
1.1
1.1
—
—
—
0
0
22
219
1.00
0.00
1.5
1.3
—
—
—
0
0
14
141
0.99
0.00
1.6
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
0.00
0.0
5.2
—
392.60
—
0
5
5
51
0.98
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.4
—
—
—
0
0
5
54
0.93
-0.00
1.2
1.5
—
—
—
0
0
8
80
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
76.57
—
0
7
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
54
0.93
-0.00
1.2
1.1
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.4
—
—
—
0
0
7
79
0.89
-0.00
1.7
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
15.83
—
0
6
11
110
1.00
-0.00
1.7
1.4
34.74
31.90
g/l
0.61
11
97
6
69
0.87
-0.00
1.3
1.4
—
—
—
0
0
7
79
0.89
-0.00
1.0
1.0
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_ORAL_LEUCOPLACIA_INCLAVO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORAL_LEUCOPLACIA_INCLAVO | 1.138 [0.99, 1.31] | 0.067 |
| Birth year | 0.989 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 415 out of 2412 females with K11_ORAL_LEUCOPLACIA_INCLAVO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORAL_LEUCOPLACIA_INCLAVO | 1.208 [1.05, 1.39] | 0.008 |
| Birth year | 0.987 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 419 out of 2342 males with K11_ORAL_LEUCOPLACIA_INCLAVO died.
Mortality risk
Mortality risk for people of age
years, who have K11_ORAL_LEUCOPLACIA_INCLAVO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.085% | 0.16% |
| 5 | 0.554% | 1.325% |
| 10 | 1.446% | 3.321% |
| 15 | 2.758% | 6.967% |
| 20 | 4.837% | 11.545% |
Relationships between endpoints
↥Index endpoint: K11_ORAL_LEUCOPLACIA_INCLAVO – Oral leukoplakia, including avohilmo
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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