skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
569 |
4. Check minimum number of eventsNone |
569 |
5. Include endpointsNone |
569 |
6. Filter based on genotype QC (FinnGen only) |
552 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L85
- Name in latin
- Xerosis cutis
Similar endpoints
↥List of similar endpoints to
Xerosis cutis
based on the number of shared cases.
Similar with more cases:
- Other epidermal thickening
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2572 | 1334 | 1230 |
| Only index persons | 2357 | 1230 | 1127 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 68.29 | 67.94 | 68.83 |
| Only index persons | 68.76 | 68.34 | 69.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 552 | 273 | 279 |
| Unadjusted period prevalence (%) | 0.11 | 0.10 | 0.13 |
| Median age at first event (years) | 70.10 | 67.47 | 72.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 569
- Matched controls
- 5690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L85.3
ICD-10 Finland
Xerosis cutis
+∞
307.7
569
13
E0000UV, ,
ATC
13.0
160.8
472
1547
TQW80
NOMESCO Finland
Local dermatologic skincare
32.8
144.7
96
35
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.3
117.4
169
246
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
16.4
111.1
100
73
L30.9
ICD-10 Finland
Dermatitis, unspecified
6.2
99.1
248
631
R4180
NOMESCO Finland
Podiatric therapy
41.3
91.4
56
15
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
49.7
85.4
50
11
L84
ICD-10 Finland
Corns and callosities
15.5
83.4
76
56
D07AC01
ATC
betamethasone; topical
4.1
61.7
324
1378
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
21.6
57.9
44
22
L57.0
ICD-10 Finland
Actinic keratosis
5.0
56.5
147
368
L30.4
ICD-10 Finland
Erythema intertrigo
18.7
55.5
45
26
L85.89
ICD-10 Finland
Other specified epidermal thickening
+∞
52.9
50
*
D07AB08
ATC
desonide; topical
4.9
49.9
132
333
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
4.3
48.6
155
452
L30.8
ICD-10 Finland
Other specified dermatitis
12.1
47.3
49
44
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.2
44.8
105
238
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.3
44.5
142
412
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.1
43.6
147
443
D07AB02
ATC
hydrocortisone butyrate; topical
3.4
43.6
249
1063
E000001, ,
ATC
3.7
43.3
185
657
D02AE01
ATC
carbamide; topical
5.8
43.2
87
172
L29.9
ICD-10 Finland
Pruritus, unspecified
9.1
42.2
54
65
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
5.3
40.3
90
195
B35.3
ICD-10 Finland
Tinea pedis
7.3
36.3
56
84
L82
ICD-10 Finland
Seborrhoeic keratosis
3.4
32.1
148
540
L04AA06
ATC
mycophenolic acid; systemic
12.5
31.9
32
27
SPAT1153
SPAT
Removal of sutures
2.8
31.8
255
1269
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.7
31.7
117
370
SPAT1149
SPAT
Suture or treatment of traumatic wound
3.5
30.6
128
439
H02AB06
ATC
prednisolone; systemic
2.7
29.9
341
2010
S18
ICPC
Laceration/cut
2.7
29.9
331
1923
L30.3
ICD-10 Finland
Infective dermatitis
6.6
28.0
47
77
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
27.9
122
428
SPAT1301
SPAT
No procedures
2.6
26.9
245
1276
SPAT1312
SPAT
General health counselling
2.6
26.8
234
1193
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.1
26.8
82
226
A46
ICD-10 Finland
Erysipelas
3.2
26.1
124
456
-, ,
ICD-10 Finland
7.3
25.8
39
57
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
7.3
25.8
39
57
S97
ICPC
Chronic ulcer skin
4.5
25.5
66
160
B35.1
ICD-10 Finland
Tinea unguium
4.4
25.3
68
170
D07AA02
ATC
hydrocortisone; topical
3.2
25.2
118
430
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
25.1
258
1411
XQ848
NOMESCO Finland
Dermatological photography
6.9
24.6
39
60
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
24.4
337
2102
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.7
24.3
179
833
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.7
24.3
84
252
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.2
23.9
51
105
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
23.5
222
1160
R60.0
ICD-10 Finland
Localized oedema
3.1
23.5
115
429
SPAT1249
SPAT
Treatment-related counselling outside office
2.4
23.5
274
1576
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
9.4
23.1
28
31
E000006, ,
ATC
4.1
22.6
67
180
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.1
22.4
49
103
D05BB02
ATC
acitretin; oral
8.3
22.3
30
38
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
8.3
22.3
30
38
D07AD01
ATC
clobetasol; topical
2.9
22.0
126
512
UJF32
NOMESCO Finland
Coloscopy
2.5
21.9
203
1045
C03CA01
ATC
furosemide; systemic
2.4
21.9
247
1389
D07AC13
ATC
mometasone; topical
2.5
21.8
204
1055
B07.9
ICD-10 Finland
Verruca simplex
5.8
21.8
41
75
R06AX27
ATC
desloratadine; oral
2.5
21.4
178
871
E000003, ,
ATC
5.0
21.2
47
100
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
8.4
21.1
28
35
D02AX
ATC
Other emollients and protectives
6.2
20.7
36
61
L20.0
ICD-10 Finland
Besnier prurigo
4.3
20.6
57
145
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
5.1
20.2
44
92
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
20.1
214
1165
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.6
19.9
143
650
R06AE07
ATC
cetirizine; oral
2.3
19.8
264
1576
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
5.5
19.7
39
75
NH3BG
NOMESCO Finland
MRI of foot
47.8
19.3
23
5
TK800
NOMESCO Finland
Hemodialysis
7.8
19.2
27
36
E000002, ,
ATC
3.2
19.1
84
292
J01DB01
ATC
cefalexin; oral
3.1
19.1
495
3902
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.6
18.8
66
199
D07BC01
ATC
betamethasone and antiseptics; topical
3.0
18.2
93
353
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
5.6
17.5
34
64
J01MA02
ATC
ciprofloxacin; systemic
2.1
17.3
262
1622
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.8
16.5
95
384
SPAT1263
SPAT
Sampling
2.1
16.4
274
1749
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.2
16.4
208
1197
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.9
16.1
83
316
SPAT1254
SPAT
Administration of medicine
2.5
16.0
117
531
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.2
15.8
181
998
SPAT1310
SPAT
Counselling related to known health issue
2.1
15.7
212
1244
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
15.3
82
318
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
15.2
158
835
L04AD01
ATC
ciclosporin; systemic
6.7
15.0
24
37
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
5.5
14.8
29
55
SPAT1216
SPAT
Assessment of functional ability
2.3
14.6
127
622
H02AB04
ATC
methylprednisolone; systemic
2.5
14.6
108
492
AA1AD
NOMESCO Finland
CT of head and brain
2.1
14.5
196
1145
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.0
14.2
268
1760
SPAT1101
SPAT
Orthostatic test
3.8
14.2
45
126
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.4
14.1
53
167
Z94.0
ICD-10 Finland
Kidney transplant status
20.7
13.9
20
10
XQ802
NOMESCO Finland
Epicutan test
4.3
13.7
36
88
SPAT1210
SPAT
Application of cast or individual aid
4.0
13.7
40
106
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
16.7
13.5
21
13
SPAT1255
SPAT
Intravenous administration of medicine
3.1
13.5
58
198
RJ190, ,
NOMESCO Finland
143.3
13.5
14
*
127
Kela drug reimbursment
Transplant complication
11.9
13.4
24
21
SPAT1260
SPAT
Consultation of another employee
2.3
13.4
126
636
L29
ICD-10 Finland
Pruritus
10.0
13.3
26
27
D01AE16
ATC
amorolfine; topical
2.5
13.3
93
411
RJ410, ,
NOMESCO Finland
41.1
13.2
16
*
L04AX01
ATC
azathioprine; systemic
4.3
13.2
35
86
E000007, ,
ATC
3.5
13.2
46
138
D07CC01
ATC
betamethasone and antibiotics; topical
2.5
13.1
90
395
RJ421, ,
NOMESCO Finland
51.2
12.9
15
*
SPAT1285
SPAT
Provision of consultation response
3.5
12.9
46
140
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
12.8
214
1338
M79.6
ICD-10 Finland
Pain in limb
1.9
12.6
252
1671
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
25.0
12.5
17
7
J01FF01
ATC
clindamycin; systemic
2.0
12.5
169
980
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
12.4
83
359
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
5.5
12.4
24
45
L17
ICPC
Foot/toe symptom/complaint
2.0
12.4
182
1086
A41.8
ICD-10 Finland
Other specified sepsis
6.0
12.3
22
38
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
12.2
97
454
NH3CG
NOMESCO Finland
Extensive MRI of foot
16.3
12.2
19
12
SPAT1325
SPAT
Vaccination
1.9
12.2
227
1465
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.6
12.2
80
343
S29
ICPC
Skin symptom/complaint other
2.2
12.1
126
660
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
12.1
254
1704
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.6
12.0
29
66
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.8
12.0
22
39
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
11.9
79
340
N03AX12
ATC
[U] gabapentin; oral
2.2
11.9
116
592
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
11.9
118
607
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.9
11.9
231
1510
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.8
11.8
37
103
A02BC02
ATC
pantoprazole; systemic
1.9
11.8
397
3088
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.8
11.7
62
238
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
30.7
11.7
15
5
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.7
11.6
68
275
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
11.4
186
1144
N02BE01
ATC
paracetamol; systemic, rectal
2.7
11.4
517
4466
R50.9
ICD-10 Finland
Fever, unspecified
2.3
11.4
98
475
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.6
11.3
71
298
SPAT1229
SPAT
Assessment of need for aid
2.7
11.3
62
243
L30.0
ICD-10 Finland
Nummular dermatitis
3.8
11.2
35
97
SPAT1211
SPAT
Application of soft bandage
2.7
11.2
64
256
L29.8
ICD-10 Finland
Other pruritus
10.3
11.1
21
21
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
5.0
11.0
24
50
P01AB01
ATC
metronidazole; oral, rectal
1.8
11.0
228
1512
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
10.9
78
348
L50.3
ICD-10 Finland
Dermatographic urticaria
5.3
10.9
22
43
N18.8
ICD-10 Finland
Other chronic renal failure
5.1
10.8
23
47
RJ411, ,
NOMESCO Finland
18.2
10.8
16
9
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
28.6
10.8
14
5
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
10.7
50
179
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
22.0
10.7
15
7
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
10.7
211
1374
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.1
10.7
30
77
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
8.2
10.7
23
29
NHQ40
NOMESCO Finland
Amputation of toe
10.3
10.6
20
20
M25.5
ICD-10 Finland
Pain in joint
1.9
10.6
186
1168
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.8
10.6
24
52
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
10.5
237
1607
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
5.6
10.5
20
37
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
112.0
10.5
11
*
L85.9
ICD-10 Finland
Epidermal thickening, unspecified
+∞
10.4
10
*
RJ511, ,
NOMESCO Finland
+∞
10.4
10
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
5.0
10.3
22
45
R06.0
ICD-10 Finland
Dyspnoea
1.9
10.1
179
1123
V03AE01
ATC
polystyrene sulfonate; oral
11.6
10.1
18
16
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.0
10.1
46
163
D07XC01
ATC
betamethasone; topical
2.3
10.1
83
394
M54.5
ICD-10 Finland
Low back pain
1.8
10.0
206
1353
H3603, E103,
ICD-10 Finland
40.8
10.0
12
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
10.0
126
706
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.7
10.0
54
210
L89
ICD-10 Finland
Decubitus ulcer and pressure area
17.1
9.9
15
9
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.4
9.9
69
304
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
9.9
227
1541
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
9.9
76
350
WZA90
NOMESCO Finland
Other medical or dental certificate
1.9
9.7
139
812
ZXC50
NOMESCO Finland
Cryotherapy
3.9
9.7
29
78
K59.09
ICD-10 Finland
Constipation, unspecified
2.7
9.7
56
225
J01MA14
ATC
moxifloxacin; systemic
2.5
9.7
64
275
S19
ICPC
Skin injury other
3.6
9.6
32
93
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.9
9.6
21
44
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
9.5
111
603
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
9.5
96
494
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.7
9.5
30
84
NH3DG
NOMESCO Finland
Very extensive MRI of foot
101.7
9.4
10
*
RJ422, ,
NOMESCO Finland
101.7
9.4
10
*
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.7
9.4
51
198
A12AA04
ATC
calcium carbonate; oral
8.2
9.4
20
25
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
12.6
9.4
16
13
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
9.4
214
1444
B03XA02
ATC
darbepoetin alfa; parenteral
4.8
9.4
21
45
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
4.2
9.3
25
62
K07.60
ICD-10 Finland
Snapping jaw
3.4
9.3
34
105
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.4
9.2
23
54
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
9.2
251
1781
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
9.2
70
321
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
11.7
9.1
16
14
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
9.0
251
1788
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
8.9
69
318
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
4.8
8.9
20
43
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.1
8.9
24
60
SPAT1053
SPAT
Memory test
2.0
8.8
111
619
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.1
8.8
37
125
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
8.7
104
569
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
50.8
8.7
10
*
SPAT1252
SPAT
Overall medication plan or its review
2.5
8.5
54
227
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.5
8.5
53
221
XKD00
NOMESCO Finland
Uroflowmetry
2.0
8.5
112
634
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.4
8.5
30
91
S06
ICPC
Rash localized
2.8
8.4
42
156
C03DA01
ATC
spironolactone; oral
2.1
8.4
85
437
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
13.0
8.4
14
11
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
8.4
115
660
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.2
8.4
33
107
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.5
8.2
51
212
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
8.2
376
3029
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
14.7
8.2
13
9
EBA00
NOMESCO Finland
Extraction of tooth
1.7
8.2
192
1297
L21
ICD-10 Finland
Seborrhoeic dermatitis
4.9
8.2
18
38
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.7
8.1
43
165
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
8.1
68
324
R01AD58
ATC
fluticasone, combinations; nasal
1.9
8.1
120
706
D06BB10
ATC
imiquimod; topical
2.8
8.1
42
160
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
8.1
30
94
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
8.0
168
1097
C08CA05
ATC
nifedipine; systemic
2.6
8.0
46
184
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.5
8.0
27
79
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
8.0
100
555
D05AX52
ATC
calcipotriol, combinations; topical
3.0
8.0
35
121
UKC02
NOMESCO Finland
Cystoscopy
1.9
8.0
111
639
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
8.0
32
105
KMAK, ,
NOMESCO Finland
1.7
8.0
260
1913
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.6
8.0
48
197
A02BC03
ATC
lansoprazole; oral
1.7
7.9
177
1177
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
13.3
7.9
13
10
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
13.3
7.9
13
10
S02
ICPC
Pruritus
3.4
7.9
28
85
M13.9
ICD-10 Finland
Arthritis, unspecified
2.5
7.9
52
223
N02AX02
ATC
tramadol; systemic, rectal
1.7
7.8
250
1827
R03DC03
ATC
montelukast; oral
2.0
7.8
93
508
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.7
7.8
42
163
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.1
7.8
33
112
B01AC04
ATC
clopidogrel; oral
1.9
7.8
117
691
C07AB07
ATC
bisoprolol; oral
1.6
7.7
301
2310
137
Kela drug reimbursment
Uraemia requiring dialysis
15.3
7.7
12
8
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.7
7.7
41
158
C01DA14
ATC
isosorbide mononitrate; oral
1.9
7.7
117
693
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
7.7
151
967
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.7
7.7
24
67
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.7
7.7
24
67
L01BA01
ATC
methotrexate; systemic
3.7
7.7
24
67
SPAT1100
SPAT
Long-term monitoring of blood pressure
2.4
7.6
51
220
B05DA
ATC
Isotonic solutions
18.7
7.6
11
6
A10AE04
ATC
insulin glargine; parenteral
2.2
7.6
67
326
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
7.6
55
246
A11CC03
ATC
alfacalcidol; systemic
4.2
7.6
20
49
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.5
7.6
48
202
Z49.1
ICD-10 Finland
Extracorporeal dialysis
10.2
7.6
14
14
D01BA02
ATC
terbinafine; oral
1.8
7.6
153
988
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
7.5
70
348
SPAT1167
SPAT
Insertion of urinary catheter
3.2
7.5
29
93
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
7.5
55
248
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
7.4
94
524
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.7
7.4
23
64
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
3.7
7.4
23
64
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
7.4
248
1829
NF1AA
NOMESCO Finland
Hip X-ray examination
2.2
7.4
64
310
R03BB04
ATC
tiotropium bromide; inhalant
2.0
7.3
79
416
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.9
7.3
21
55
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.2
7.3
63
304
R22.7
ICD-10 Finland
Localized swelling, mass and lump, multiple sites
+∞
7.3
7
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
7.3
7
*
D06BX01
ATC
metronidazole; topical
2.2
7.3
66
325
J01CA04
ATC
amoxicillin; systemic
1.8
7.2
439
3746
J02AC01
ATC
fluconazole; systemic
1.7
7.2
189
1308
S01
ICPC
Pain/tenderness of skin
3.0
7.2
32
112
L24.8
ICD-10 Finland
Irritant contact dermatitis due to other agents
30.4
7.2
9
*
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
30.4
7.2
9
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
7.2
338
2700
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
20.3
7.2
10
5
Z49.2
ICD-10 Finland
Other dialysis
20.3
7.2
10
5
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
20.3
7.2
10
5
B05DB
ATC
Hypertonic solutions
20.3
7.2
10
5
N03AX16
ATC
[U] pregabalin
1.8
7.1
135
853
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
7.1
45
189
A10AE05
ATC
insulin detemir; parenteral
2.8
7.1
36
135
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
12.2
7.1
12
10
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.7
7.1
22
61
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.0
7.1
30
102
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.6
7.1
23
66
L16
ICPC
Ankle symptom/complaint
2.1
7.1
70
357
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
7.0
161
1073
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
7.0
120
736
A98
ICPC
Health maint/preventive medicine
2.7
7.0
539
4945
GD1AD
NOMESCO Finland
Thorax CT examination
2.6
7.0
41
166
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
7.0
31
108
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.2
7.0
60
289
D09AB01
ATC
zinc bandage without supplements; topical
6.5
7.0
17
27
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
7.0
74
387
SPAT1324
SPAT
Screening procedure
2.0
7.0
74
387
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.6
7.0
19
35
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.4
7.0
47
204
F01
ICPC
Eye pain
3.7
6.9
22
62
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
2.9
6.9
33
120
L04AD02
ATC
tacrolimus; systemic
14.0
6.9
11
8
A10AE06
ATC
insulin degludec; parenteral
3.4
6.9
24
72
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
6.9
163
1096
L04AX03
ATC
methotrexate; systemic
2.2
6.9
57
271
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
11.1
6.8
12
11
J01CE02
ATC
phenoxymethylpenicillin; oral
1.6
6.8
356
2899
C08CA01
ATC
amlodipine; oral
1.6
6.8
229
1681
N05CF01
ATC
zopiclone; oral
1.6
6.8
188
1316
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.6
6.7
39
157
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
3.0
6.7
30
105
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.8
6.7
20
54
J01DA01
ATC
[U] cefalexin
1.6
6.7
335
2695
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
6.7
120
746
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
6.7
73
386
SCA01
NOMESCO Finland
Preventive oral health care, short
1.7
6.7
143
935
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.3
6.6
25
79
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.0
6.6
74
394
I20.09
ICD-10 Finland
Unstable angina
2.4
6.6
46
202
D01AC02
ATC
miconazole; topical
2.3
6.6
51
235
Z49.0
ICD-10 Finland
Preparatory care for dialysis
12.4
6.6
11
9
SPAT1262
SPAT
Handing over of treatment supplies
1.8
6.6
107
645
L03
ICPC
Low back symptom/complaint
1.7
6.6
151
1004
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.1
6.6
27
90
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.9
6.5
84
470
R42
ICD-10 Finland
Dizziness and giddiness
1.7
6.5
137
891
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
6.5
82
457
T89
ICPC
Diabetes insulin dependent
3.0
6.4
28
97
J02AC02
ATC
itraconazole; systemic
1.8
6.4
95
557
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
6.4
148
986
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.6
6.4
183
1288
SPAT1043
SPAT
Audiometry
2.0
6.3
73
393
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
5.6
6.3
17
31
A07AA02
ATC
nystatin; oral
2.5
6.3
39
162
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.7
6.3
33
126
H13
ICPC
Plugged feeling ear
1.7
6.3
122
773
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.2
6.3
11
10
L85.81
ICD-10 Finland
Keratosis pilaris
+∞
6.3
6
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
6.3
95
561
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
6.2
44
195
J05AB11
ATC
valaciclovir; oral
1.9
6.2
85
485
K30
ICD-10 Finland
Functional dyspepsia
2.0
6.2
65
338
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
6.2
183
1295
L04AA01
ATC
[U] ciclosporin
6.4
6.2
15
24
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.4
6.2
22
67
R13
ICD-10 Finland
Dysphagia
2.3
6.2
47
215
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
6.1
155
1055
C09CA01
ATC
losartan; oral
1.6
6.1
155
1055
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
6.1
357
2946
XQ800
NOMESCO Finland
Prick test
2.4
6.1
40
171
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
6.1
42
184
A07EC01
ATC
sulfasalazine; oral, rectal
2.3
6.1
46
210
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
6.1
109
676
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
6.1
101
613
M77.4
ICD-10 Finland
Metatarsalgia
2.6
6.1
35
141
PD4DG
NOMESCO Finland
Very extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
10.2
6.1
11
11
N18.0
ICD-10 Finland
End-stage renal disease
10.2
6.1
11
11
N30.0
ICD-10 Finland
Acute cystitis
1.9
6.0
87
505
L72.1
ICD-10 Finland
Trichilemmal cyst
2.4
6.0
42
185
L71.8
ICD-10 Finland
Other rosacea
5.6
6.0
16
29
R03AC02
ATC
salbutamol; inhalant
1.5
6.0
292
2311
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
207
578
5.06
71.24
17.6
7.1
—
—
—
0
0
144
420
4.25
44.80
2.9
2.5
6.48
6.77
ug/l
0.04
128
365
106
259
4.80
41.21
1.2
1.2
229.81
251.31
u/ml
0.07
101
238
432
2653
3.61
39.54
11.5
8.7
4.18
4.19
e9/l
0.05
408
2317
121
349
4.13
37.77
3.1
2.5
55.09
65.57
ml/min/173m2
2.59
66
150
228
1025
3.04
35.03
7.7
4.0
1.02
1.02
kg/l
0.50
16
158
161
603
3.33
33.66
8.3
4.8
1.11
1.03
mmol/l
2.26
150
548
351
2049
2.86
32.27
5.9
4.4
34.73
35.24
g/l
0.96
329
1897
251
1254
2.79
30.87
7.7
4.0
0.00
0.01
estimate
0.50
38
409
119
397
3.53
29.60
2.1
3.1
65.55
66.49
g/l
0.81
111
363
104
321
3.74
29.06
8.6
7.3
23.49
24.56
mmol/l
1.47
99
304
238
1235
2.59
26.17
3.2
2.1
3.21
3.13
mg/l
0.17
211
1053
358
2260
2.58
25.77
6.8
3.7
0.00
0.00
estimate
0.50
44
459
104
351
3.40
25.17
4.2
3.5
101.11
81.15
ng/l
1.34
97
310
264
1465
2.50
24.86
3.8
2.5
54.62
62.16
u/l
1.09
240
1357
358
2286
2.53
24.73
6.8
3.7
0.00
0.00
estimate
-0.00
38
417
275
1561
2.47
24.56
4.8
3.0
2164.93
1328.47
ng/l
1.50
252
1342
350
2249
2.45
23.27
7.8
4.9
0.00
0.00
estimate
-0.00
39
427
167
768
2.66
23.05
3.5
2.3
11.64
12.91
umol/l
1.60
157
710
465
3434
2.94
22.74
6.6
4.1
14.89
12.84
mm/h
1.90
444
3139
408
2834
2.55
22.48
7.1
4.8
6.83
6.73
mmol/l
0.40
386
2662
309
1899
2.37
22.45
5.5
3.8
45.36
57.19
ng/l
0.26
254
1412
254
1436
2.39
22.34
2.6
2.1
312.09
256.61
u/l
0.11
241
1347
129
539
2.80
21.31
5.8
3.8
235.48
244.89
u/l
0.60
121
507
290
1762
2.32
21.28
7.2
3.8
—
—
—
0
0
471
3562
2.87
20.84
11.3
7.4
81.00
78.70
u/l
0.44
458
3331
133
571
2.73
20.81
6.2
8.5
4.92
5.09
kpa
0.94
126
544
355
2363
2.34
20.79
10.9
6.5
1.20
1.21
mmol/l
3.92
328
2005
133
572
2.73
20.74
6.2
8.5
11.13
11.89
kpa
1.26
125
548
117
473
2.86
20.51
6.4
9.0
118.46
121.58
g/l
0.84
112
461
365
2468
2.34
20.46
7.7
6.2
13.03
11.70
umol/l
0.38
350
2345
299
1865
2.27
20.30
2.8
2.2
75.53
77.48
nmol/l
0.58
275
1640
132
572
2.70
20.24
6.1
8.5
1.66
1.41
mmol/l
0.36
91
455
151
705
2.55
19.86
3.5
2.2
2.29
2.34
g/l
0.43
144
645
329
2177
2.21
18.78
9.9
6.0
1.20
1.21
mmol/l
3.75
309
1968
216
1208
2.27
18.74
4.0
2.6
364.16
8313.31
umol/l
5.86
188
1030
452
3447
2.51
17.88
4.7
3.8
15.25
14.86
pmol/l
2.58
418
3084
49
124
4.23
17.82
2.0
1.9
—
—
—
0
0
108
450
2.73
17.71
6.0
3.2
2.14
2.07
mmol/l
0.08
92
369
180
955
2.29
17.51
1.8
1.8
1582.73
1180.27
nmol/l
3.95
140
722
421
3131
2.32
17.33
7.3
4.5
8.33
2737.79
e6/l
—
7
57
139
664
2.45
17.14
3.5
2.3
20.80
22.47
%
0.73
121
560
276
1752
2.12
16.96
5.6
3.1
—
—
—
0
0
338
2322
2.12
16.76
28.2
16.0
1.30
1.31
inr
0.06
83
663
302
2001
2.09
16.35
2.4
2.0
91.66
95.05
pmol/l
0.59
185
1048
294
1937
2.07
16.07
4.0
2.7
145.24
135.78
ug/l
0.29
276
1770
34
72
4.96
15.37
6.4
5.9
399.29
287.30
iu/ml
—
7
10
242
1509
2.05
15.13
3.7
3.0
6.72
7.52
mmol/l
2.35
211
1234
144
740
2.27
14.80
4.8
3.5
0.82
0.82
mmol/l
0.02
130
693
255
1632
2.02
14.72
3.0
3.2
2.33
2.35
mmol/l
1.24
224
1418
232
1447
2.02
14.30
4.1
3.1
335.66
327.62
mg/l
0.01
177
918
81
325
2.74
14.15
2.2
1.5
—
—
—
0
0
25
45
5.76
13.47
2.4
2.3
—
—
—
0
0
72
281
2.79
13.23
1.6
1.5
—
—
—
0
0
24
43
5.78
12.99
1.3
1.3
16590.29
255211.11
e6/l
0.75
17
27
150
823
2.12
12.89
2.2
1.8
—
—
—
0
0
498
4186
2.52
12.42
6.1
4.7
2.01
1.96
mu/l
0.35
472
3788
161
919
2.05
12.38
1.5
1.2
1.48
1.45
u/ml
0.01
46
231
43
129
3.52
12.30
1.7
1.1
—
—
—
0
0
115
581
2.23
12.11
2.8
2.3
1.78
1.78
%
0.03
101
515
114
574
2.23
12.10
2.2
1.8
—
—
—
0
0
233
1524
1.90
11.97
4.3
3.7
21.90
8.59
mg/mmol
1.49
179
949
113
570
2.23
11.93
2.0
1.8
—
—
—
0
0
522
4543
2.80
11.08
30.5
14.8
24.57
25.14
mg/l
0.12
468
3653
91
434
2.31
10.93
2.3
2.4
0.19
0.21
g/l
1.22
79
401
171
1052
1.89
10.32
1.6
1.7
212583219.68
429.17
pmol/l
1.07
151
862
495
4239
2.29
10.30
8.4
6.0
42.20
40.17
mmol/mol
3.25
475
3904
49
178
2.92
10.25
1.6
2.5
9.25
10.48
g/l
1.36
42
159
192
1228
1.85
10.25
1.8
1.6
18.28
20.58
nmol/l
1.29
169
1042
540
4828
3.32
10.04
17.3
10.4
25.27
25.20
u/l
0.03
530
4641
164
1005
1.89
9.97
2.4
1.7
1.11
1.29
mg/l
0.55
130
780
24
55
4.51
9.89
1.0
1.2
1.53
1.51
g/l
0.10
24
50
533
4744
2.95
9.75
34.2
17.5
139.19
139.68
mmol/l
3.68
528
4617
497
4288
2.26
9.73
5.4
4.0
1.36
1.28
mmol/l
1.47
455
3871
140
820
1.94
9.73
3.3
2.9
1.31
1.19
e6/l
0.17
104
479
156
949
1.89
9.66
2.7
3.1
2.45
2.45
mmol/l
0.01
143
825
51
196
2.76
9.62
1.6
2.4
3.46
3.55
g/l
0.21
44
179
533
4753
2.92
9.54
34.2
17.7
4.04
3.98
mmol/l
3.67
527
4621
51
197
2.75
9.53
1.6
2.4
6.88
7.37
g/l
1.44
44
179
51
197
2.75
9.53
1.6
2.4
—
—
—
0
0
36
115
3.27
9.36
2.2
2.5
306.44
53.27
ug/min
1.15
25
68
163
1023
1.83
9.07
3.6
2.5
6.43
4.83
e6/l
0.55
152
930
48
185
2.74
9.01
1.6
2.4
2.84
2.97
g/l
0.39
41
167
25
65
3.98
8.78
1.6
1.4
126.22
102.20
u/ml
—
9
10
33
105
3.27
8.64
1.3
1.2
2.08
7.98
u/ml
—
5
15
26
72
3.74
8.38
1.7
1.4
—
—
—
0
0
291
2193
1.67
8.21
3.2
2.6
—
—
—
0
0
32
104
3.20
8.10
1.6
1.4
—
—
—
0
0
36
126
2.98
8.05
1.5
1.2
—
—
—
0
0
36
126
2.98
8.05
1.5
1.3
—
—
—
0
0
503
4440
2.15
8.01
5.7
4.5
1.39
1.46
mmol/l
2.98
460
4039
506
4480
2.17
7.93
5.9
4.5
4.33
4.57
mmol/l
5.60
465
4107
514
4579
2.27
7.93
6.4
5.1
2.51
2.67
mmol/l
3.54
476
4178
36
128
2.93
7.84
1.5
1.2
—
—
—
0
0
25
71
3.64
7.78
1.2
1.3
—
—
—
0
0
24
68
3.64
7.49
1.3
1.3
327.18
271.10
u/ml
0.36
17
40
35
127
2.87
7.36
1.7
1.6
—
—
—
0
0
545
5019
3.04
7.21
43.5
22.1
39.53
39.92
%
0.96
524
4656
61
293
2.21
7.15
2.6
2.5
25.07
14.08
au/ml
—
6
20
545
5023
3.02
7.12
43.7
22.0
130.89
134.55
g/l
6.27
540
4937
41
166
2.58
7.01
2.7
3.8
28.77
32.57
mg/l
0.44
36
136
41
166
2.58
7.01
2.7
3.8
90.78
98.62
mg/l
0.05
36
137
30
104
2.99
6.84
1.4
1.3
—
—
—
0
0
39
158
2.58
6.67
1.7
2.5
37.04
37.98
g/l
0.43
32
140
17
29
6.01
6.65
1.2
1.2
—
—
—
0
0
317
2530
1.57
6.45
3.2
2.8
—
—
—
0
0
165
1137
1.64
6.24
3.0
2.4
—
—
—
0
0
17
32
5.44
6.20
1.2
1.2
—
94.40
—
0
5
278
2167
1.55
6.19
8.8
5.3
58.25
57.71
%
0.33
271
2038
31
117
2.74
6.09
1.5
1.6
—
—
—
0
0
40
173
2.41
5.98
2.0
2.7
0.32
0.90
g/l
0.80
31
154
496
4464
1.87
5.87
6.3
4.8
6.27
6.00
mmol/l
2.60
464
4044
279
2199
1.53
5.77
9.2
5.6
25.95
27.24
%
1.21
273
2061
32
129
2.57
5.55
1.3
1.4
236.47
278.59
ug/g
0.51
19
78
17
47
3.70
5.52
1.7
1.4
—
—
—
0
0
17
47
3.70
5.52
1.7
1.4
—
—
—
0
0
184
1344
1.55
5.30
4.4
3.2
0.54
0.52
e6/l
0.05
159
1031
26
99
2.70
5.05
1.4
1.3
230.04
277.57
miu/ml
—
6
42
190
1414
1.52
4.96
5.7
4.6
22.24
21.19
%
0.45
103
699
17
53
3.28
4.65
1.4
1.3
—
—
—
0
0
19
64
3.04
4.59
1.7
1.6
—
—
—
0
0
8
8
10.12
4.53
1.0
1.0
—
—
—
0
0
40
196
2.12
4.51
1.5
1.3
—
—
—
0
0
14
42
3.39
4.06
1.5
1.5
30.64
25.75
u/l
—
8
37
11
22
5.08
4.02
1.4
1.2
—
—
—
0
0
39
199
2.03
3.98
1.0
1.0
—
—
—
0
0
18
65
2.83
3.89
8.3
6.4
12.78
11.79
mg/l
0.48
18
59
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
32
153
2.16
3.86
6.3
2.8
0.28
0.38
u/ml
1.47
16
87
336
2878
1.41
3.86
4.0
3.2
65.86
52.32
u/l
1.18
309
2661
14
38
3.75
3.82
1.1
1.1
—
—
—
0
0
20
78
2.62
3.75
1.9
1.5
—
—
—
0
0
20
78
2.62
3.75
1.9
1.5
—
—
—
0
0
34
169
2.08
3.73
2.3
3.1
—
—
—
0
0
189
1472
1.43
3.73
4.4
3.2
43.23
120.99
e6/l
0.82
162
1149
106
738
1.54
3.67
1.3
1.3
25.89
38.20
iu/ml
1.02
28
241
21
85
2.53
3.67
1.4
1.5
—
—
—
0
0
67
419
1.68
3.61
2.1
2.0
365.56
387.40
nmol/l
0.37
62
384
127
924
1.48
3.57
5.8
4.0
624.88
280.45
ng/l
0.46
99
741
21
87
2.47
3.51
2.0
1.7
—
—
—
0
0
34
175
2.00
3.41
2.0
2.1
41.03
39.00
u/l
0.18
34
153
79
523
1.59
3.41
3.8
2.8
7.82
8.46
umol/l
0.12
68
459
80
533
1.58
3.36
1.6
1.4
—
—
—
0
0
8
14
5.78
3.35
1.1
1.0
2260.63
1690.86
miu/ml
—
8
14
22
98
2.29
3.16
1.4
1.3
—
—
—
0
0
25
118
2.17
3.15
1.9
1.6
—
—
—
0
0
24
112
2.19
3.11
1.9
1.6
—
—
—
0
0
97
690
1.49
3.03
1.3
1.3
16.69
12.43
u/ml
0.18
39
245
25
121
2.12
2.97
1.5
1.6
—
—
—
0
0
13
46
2.87
2.93
2.2
1.7
—
—
—
0
0
13
46
2.87
2.93
2.2
1.7
—
—
—
0
0
13
46
2.87
2.93
2.2
1.7
—
—
—
0
0
14
52
2.73
2.90
1.2
1.2
3.80
1.78
u/ml
—
5
18
14
52
2.73
2.90
1.1
1.1
—
—
—
0
0
17
71
2.44
2.82
1.4
1.5
—
—
—
0
0
464
4296
1.43
2.82
22.8
14.1
71.36
77.56
ml/min/173m2
6.06
382
3538
34
189
1.85
2.77
2.1
1.6
—
—
—
0
0
36
207
1.79
2.64
2.3
1.8
—
—
—
0
0
14
55
2.58
2.63
1.9
1.7
—
—
—
0
0
17
74
2.34
2.60
1.5
1.5
—
—
—
0
0
213
1773
1.32
2.60
5.5
5.3
1.79
2.63
ug/l
2.86
193
1570
13
50
2.64
2.54
2.0
1.7
—
—
—
0
0
13
50
2.64
2.54
1.1
1.5
0.22
0.26
nmol/l
—
8
36
23
117
2.01
2.44
2.2
2.1
12.96
12.95
mg/l
0.00
23
107
11
38
2.93
2.42
1.8
2.4
—
—
—
0
0
13
52
2.54
2.37
3.1
2.4
—
—
—
0
0
7
17
4.16
2.36
5.0
3.8
87.86
100.18
%
—
7
17
7
17
4.16
2.36
1.0
1.1
—
—
—
0
0
22
112
2.00
2.33
1.2
1.1
—
—
—
0
0
6
14
4.32
2.15
1.0
1.1
—
—
—
0
0
6
14
4.32
2.15
1.8
1.2
—
—
—
0
0
9
30
3.03
2.15
1.9
1.4
0.28
0.17
e9/l
—
9
24
10
36
2.81
2.14
1.7
1.1
—
—
—
0
0
88
658
1.40
2.12
1.5
1.5
—
—
—
0
0
64
451
1.47
2.12
1.6
1.8
1.67
1.54
%
0.40
56
389
21
110
1.94
2.08
1.4
1.3
—
—
—
0
0
9
31
2.93
2.08
1.9
1.4
480.67
535.58
e6/l
—
9
24
21
111
1.93
2.03
1.2
1.0
—
10.96
—
0
10
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
26
3.11
2.02
1.1
1.2
—
—
—
0
0
11
45
2.47
1.94
1.0
1.1
—
—
—
0
0
40
262
1.57
1.87
2.9
2.7
0.57
0.25
e6/l
0.31
40
256
8
28
2.88
1.87
1.5
2.5
13.63
13.41
%
—
8
28
11
46
2.42
1.86
1.0
1.1
—
—
—
0
0
22
123
1.82
1.82
1.7
1.5
—
—
—
0
0
15
73
2.08
1.82
1.1
1.0
—
—
—
0
0
8
29
2.78
1.79
3.5
4.1
—
—
—
0
0
5
13
3.87
1.72
1.4
1.2
—
—
—
0
0
5
13
3.87
1.72
1.0
1.1
—
—
—
0
0
5
13
3.87
1.72
1.0
1.2
—
—
—
0
0
12
55
2.21
1.68
1.1
1.2
14.20
8.16
u/ml
—
5
25
39
262
1.52
1.66
1.5
1.2
104.39
119.70
iu/ml
0.11
18
109
10
42
2.41
1.62
2.2
1.8
—
—
—
0
0
19
106
1.82
1.60
1.2
1.2
13.79
8.01
u/l
0.87
13
79
8
33
2.44
1.54
1.0
1.1
—
—
—
0
0
7
27
2.61
1.52
1.1
1.5
—
—
—
0
0
6
21
2.88
1.51
1.0
1.3
—
—
—
0
0
9
37
2.45
1.48
1.0
1.3
—
—
—
0
0
69
529
1.35
1.46
3.4
4.4
5.35
30.17
ug/l
1.05
60
456
12
59
2.06
1.44
1.7
1.3
—
—
—
0
0
5
16
3.14
1.44
1.0
1.0
—
—
—
0
0
5
16
3.14
1.44
1.8
1.6
47.06
59.65
ug/l
—
5
16
15
81
1.87
1.41
1.5
1.9
4.25
4.99
mmol/24h
0.38
15
68
13
67
1.96
1.39
1.6
1.5
—
—
—
0
0
12
60
2.02
1.39
1.7
1.3
—
—
—
0
0
12
60
2.02
1.39
1.7
1.3
—
—
—
0
0
101
1224
0.79
1.38
1.9
1.6
1.36
1.35
mmol/l
0.07
89
1015
6
23
2.63
1.37
1.8
1.6
—
—
—
0
0
36
249
1.48
1.37
2.9
2.9
4.04
4.50
pmol/l
1.68
29
222
12
61
1.99
1.33
1.7
1.3
—
—
—
0
0
12
61
1.99
1.33
1.7
1.3
—
—
—
0
0
12
61
1.99
1.33
1.7
1.3
—
—
—
0
0
6
24
2.52
1.30
1.2
1.1
—
—
—
0
0
19
114
1.69
1.29
3.5
9.8
104.29
105.31
mmol/l
0.36
14
103
8
36
2.24
1.24
1.5
1.6
—
—
—
0
0
5
19
2.65
1.22
2.2
1.6
—
—
—
0
0
6
26
2.32
1.19
3.0
3.0
101.00
103.35
nmol/l
—
6
26
6
26
2.32
1.19
1.7
1.1
—
—
—
0
0
6
26
2.32
1.19
1.7
1.1
—
—
—
0
0
8
38
2.12
1.19
1.0
1.4
—
—
—
0
0
41
304
1.38
1.11
2.0
1.7
—
—
—
0
0
5
21
2.39
1.09
1.6
1.1
—
—
—
0
0
5
21
2.39
1.09
1.6
1.1
—
—
—
0
0
16
97
1.67
1.07
2.6
2.4
17.63
16.38
%
—
8
45
20
299
0.66
1.05
1.9
1.6
—
—
—
0
0
17
106
1.62
1.04
2.7
1.7
2.75
6.16
iu/l
—
8
25
7
35
2.01
1.00
1.1
1.1
—
—
—
0
0
7
35
2.01
1.00
1.1
1.1
—
—
—
0
0
7
35
2.01
1.00
1.1
1.1
—
—
—
0
0
10
54
1.87
0.97
1.6
1.6
—
—
—
0
0
11
62
1.79
0.94
1.0
1.1
—
52.82
—
0
11
43
333
1.32
0.91
1.8
2.2
12.00
12.32
nmol/l
0.09
37
290
16
104
1.55
0.85
1.6
1.5
—
—
—
0
0
162
1459
1.15
0.81
4.7
3.2
32.62
32.22
u/l
0.06
156
1384
6
34
1.77
0.76
1.2
1.1
—
—
—
0
0
6
34
1.77
0.76
1.2
1.1
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
15
99
1.53
0.76
1.1
1.4
—
—
—
0
0
15
99
1.53
0.76
1.1
1.4
—
—
—
0
0
5
25
2.01
0.73
1.4
1.2
—
—
—
0
0
5
25
2.01
0.73
1.0
1.3
—
—
—
0
0
9
56
1.62
0.72
1.1
1.0
—
—
—
0
0
11
68
1.63
0.72
2.1
2.8
3.94
4.64
e9/l
0.83
11
68
5
26
1.93
0.71
1.0
1.5
—
—
—
0
0
5
26
1.93
0.71
1.0
1.5
—
—
—
0
0
10
61
1.65
0.69
1.2
1.3
—
—
—
0
0
5
27
1.86
0.68
1.4
1.2
—
—
—
0
0
5
27
1.86
0.68
1.4
1.2
—
—
—
0
0
11
71
1.56
0.62
2.1
3.0
56.45
59.25
%
0.33
11
71
28
356
0.78
0.62
3.2
2.2
—
—
—
0
0
16
113
1.43
0.61
1.3
1.5
—
—
—
0
0
8
50
1.61
0.61
1.9
1.7
—
—
—
0
0
38
311
1.24
0.57
5.9
3.5
0.95
2.12
mmol/l
2.02
31
223
15
108
1.40
0.53
1.1
1.2
—
—
—
0
0
6
40
1.51
0.51
1.5
1.7
—
—
—
0
0
7
45
1.56
0.49
2.0
1.7
—
—
—
0
0
26
208
1.26
0.49
7.1
3.9
23.91
25.06
mmol/l
1.65
26
195
92
1013
0.89
0.44
2.9
3.2
0.54
0.79
ug/l
5.25
74
686
5
31
1.62
0.43
1.8
1.7
99.20
84.35
umol/l
—
5
31
5
31
1.62
0.43
1.2
1.2
—
—
—
0
0
15
113
1.34
0.43
1.3
1.2
—
—
—
0
0
69
617
1.13
0.41
5.2
4.6
32.61
32.17
%
0.15
49
405
0
19
0.00
0.39
0.0
1.1
—
402.55
—
0
11
28
321
0.87
0.27
2.9
2.0
—
—
—
0
0
8
66
1.22
0.27
1.0
1.2
—
—
—
0
0
10
78
1.29
0.24
1.4
1.5
—
—
—
0
0
5
40
1.25
0.22
1.4
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
7
63
1.11
0.17
1.0
1.1
—
—
—
0
0
7
67
1.05
0.08
3.9
3.4
—
—
—
0
0
80
782
1.03
0.05
3.7
3.1
2.03
2.40
e6/l
0.20
49
443
19
179
1.06
0.05
2.5
2.1
—
—
—
0
0
15
140
1.07
0.04
2.6
2.1
—
—
—
0
0
11
119
0.92
0.04
1.3
1.6
—
—
—
0
0
50
497
1.01
0.00
4.4
3.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.2
—
77.14
—
0
9
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
89.14
—
0
7
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_XEROSCUT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_XEROSCUT | 1.673 [1.27, 2.2] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.023 |
During the follow-up period (1.1.1998 — 31.12.2019), 223 out of 875 females with L12_XEROSCUT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_XEROSCUT | 2.043 [1.5, 2.79] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 277 out of 820 males with L12_XEROSCUT died.
Mortality risk
Mortality risk for people of age
years, who have L12_XEROSCUT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.113% | 0.411% |
| 5 | 0.808% | 2.582% |
| 10 | 2.019% | 6.221% |
| 15 | 3.996% | 12.021% |
| 20 | 7.158% | 19.296% |
Relationships between endpoints
↥Index endpoint: L12_XEROSCUT – Xerosis cutis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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