Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
490 |
4. Check minimum number of eventsNone |
490 |
5. Include endpoints |
532 |
6. Filter based on genotype QC (FinnGen only) |
512 |
Control definitions (FinnGen only)
- Control exclude
- M13_SYSTCONNECT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M30-M36
- Name in latin
- Polyarteritis nodosa et condiciones cognatae
Similar endpoints
↥List of similar endpoints to
Polyarteritis nodosa and related conditions
based on the number of shared cases.
Similar with more cases:
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5194 | 2773 | 2381 |
| Only index persons | 3827 | 2036 | 1791 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.08 | 0.07 |
| Only index persons | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 43.91 | 57.85 | 27.24 |
| Only index persons | 38.04 | 54.00 | 19.89 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 512 | 307 | 205 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.09 |
| Median age at first event (years) | 54.16 | 52.80 | 56.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 532
- Matched controls
- 5320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M30.0
ICD-10 Finland
Polyarteritis nodosa
+∞
231.7
205
*
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
+∞
158.5
144
*
L04AX01
ATC
azathioprine; systemic
22.0
158.2
126
74
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
9.2
117.2
176
271
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
94.7
88
*
L04AA06
ATC
mycophenolic acid; systemic
31.2
84.1
56
20
H02AB06
ATC
prednisolone; systemic
5.8
78.1
389
1705
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.7
68.6
299
1148
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
7.6
65.8
105
167
M30.3
ICD-10 Finland
Mucocutaneous lymph node syndrome [Kawasaki]
+∞
60.6
57
*
L04AX03
ATC
methotrexate; systemic
6.0
58.3
119
242
M05BA04
ATC
alendronic acid; oral
5.6
49.9
108
230
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.6
47.3
83
144
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.1
41.8
101
235
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
8.6
40.3
54
69
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
40.1
38
*
D72.1
ICD-10 Finland
Eosinophilia
79.5
39.6
44
6
J45.1
ICD-10 Finland
Nonallergic asthma
5.1
39.3
92
208
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.6
39.0
173
628
R50.9
ICD-10 Finland
Fever, unspecified
3.9
38.8
142
453
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
38.0
36
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.5
37.9
66
113
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
36.5
312
1658
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.3
36.4
112
314
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.9
36.4
71
136
J45.9
ICD-10 Finland
Asthma, unspecified
3.5
35.7
164
605
H02AB07
ATC
prednisone; oral
3.9
35.3
126
393
TGC00
NOMESCO Finland
Bronchial lavation
8.6
34.6
46
58
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.0
32.7
77
174
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
6.0
32.6
61
112
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.8
32.2
118
373
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
64.2
31.5
36
6
ZX120
NOMESCO Finland
Intravenous
4.2
31.1
93
254
4461A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Acute febrile mucocutaneous lymph node syndrome [MCLS]
+∞
30.5
29
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.1
30.4
56
101
H02AB04
ATC
methylprednisolone; systemic
3.5
29.2
121
413
P01BA02
ATC
hydroxychloroquine; oral
4.5
27.5
72
177
J33.0
ICD-10 Finland
Polyp of nasal cavity
7.9
27.1
38
51
L01AA01
ATC
cyclophosphamide; systemic
79.5
27.1
30
*
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
284.7
27.0
27
*
H02AB09
ATC
hydrocortisone; systemic
8.3
26.7
36
46
J01MA12
ATC
levofloxacin; systemic
3.1
26.4
138
540
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
26.3
25
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
26.2
191
894
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
8.1
25.3
35
46
C03CA01
ATC
furosemide; systemic
2.6
24.7
212
1072
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.8
23.8
82
246
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
9.2
23.5
29
33
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.0
23.4
72
199
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.1
23.4
70
190
J32.4
ICD-10 Finland
Chronic pansinusitis
21.3
23.3
34
17
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
8.4
23.2
31
39
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
23.1
22
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
23.1
22
*
R03DC03
ATC
montelukast; oral
2.9
22.9
129
522
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.4
22.1
45
89
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
22.0
21
*
A11CC03
ATC
alfacalcidol; systemic
7.8
21.8
31
42
L01BA01
ATC
methotrexate; systemic
6.2
21.6
38
65
N03AX16
ATC
[U] pregabalin
2.6
21.4
159
741
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
18.8
21.1
32
18
J33.8
ICD-10 Finland
Other polyp of sinus
8.4
21.1
28
35
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
6.0
21.0
38
67
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
21.0
20
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.2
20.5
59
155
M35.3
ICD-10 Finland
Polymyalgia rheumatica
8.3
20.2
27
34
J45.8
ICD-10 Finland
Mixed asthma
5.7
19.3
37
69
L04AD01
ATC
ciclosporin; systemic
8.4
18.9
25
31
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
18.9
18
*
R03AK08
ATC
formoterol and beclometasone; inhalant
5.1
18.8
41
86
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
69.1
17.8
20
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.2
17.8
50
129
J01FF01
ATC
clindamycin; systemic
2.3
17.8
176
925
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.3
17.4
71
236
R01AD08
ATC
fluticasone; nasal
2.3
17.4
178
947
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
17.4
140
670
D69.0
ICD-10 Finland
Allergic purpura
22.8
17.0
24
11
A02BC01
ATC
omeprazole; systemic
2.3
16.9
175
934
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
65.5
16.8
19
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
16.8
175
936
F02.89*M30.0
ICD-10 Finland
Dementia in polyarteritis nodosa
+∞
16.8
16
*
4460A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa[POLYARTERITIS NODOSA (CLASSICA)]
+∞
16.8
16
*
N02AX02
ATC
tramadol; systemic, rectal
2.2
16.6
248
1533
J01MA02
ATC
ciprofloxacin; systemic
2.2
16.4
225
1344
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.1
16.3
75
268
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
16.3
136
660
A02BC02
ATC
pantoprazole; systemic
2.2
16.2
368
2664
XG410
NOMESCO Finland
Flow-volume spirometry
4.5
15.7
39
91
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
15.7
15
*
I77.6
ICD-10 Finland
Arteritis, unspecified
87.7
15.6
17
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.9
15.6
48
132
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.6
15.6
104
453
J46
ICD-10 Finland
Status asthmaticus
6.0
15.5
28
49
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
15.4
67
231
Z49.1
ICD-10 Finland
Extracorporeal dialysis
16.7
15.4
24
15
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
15.3
131
640
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
6.3
15.3
26
43
R03AC12
ATC
salmeterol; inhalant
3.9
15.2
47
130
N18.8
ICD-10 Finland
Other chronic renal failure
6.7
15.0
24
37
TQW80
NOMESCO Finland
Local dermatologic skincare
6.2
14.9
26
44
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.8
14.9
34
74
A10AC01
ATC
insulin (human); parenteral
3.1
14.9
67
236
PAW37
NOMESCO Finland
Biopsy of temporal artery
58.4
14.9
17
*
J01MA14
ATC
moxifloxacin; systemic
3.1
14.8
68
242
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
14.8
49
142
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
25.9
14.8
20
8
L04AA01
ATC
[U] ciclosporin
14.7
14.7
24
17
R03BA05
ATC
fluticasone; inhalant
2.4
14.6
124
603
R03BA02
ATC
budesonide; inhalant
2.4
14.2
122
595
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.4
14.2
116
554
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
5.0
14.2
31
65
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.9
13.9
71
269
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
13.8
104
478
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
13.8
111
526
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
13.8
146
778
44600
ICD-8 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa
+∞
13.6
13
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
13.6
13
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.5
13.6
34
80
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
41.2
13.2
16
*
J45
ICD-10 Finland
Asthma
2.9
13.2
69
264
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.6
13.2
46
138
A46
ICD-10 Finland
Erysipelas
2.5
13.2
94
421
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.0
13.2
62
224
R03BB04
ATC
tiotropium bromide; inhalant
2.8
13.1
71
277
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
13.1
71
277
R03AC02
ATC
salbutamol; inhalant
2.0
12.9
310
2206
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
12.0
12.9
23
20
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
12.9
77
316
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
5.5
12.9
25
47
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.6
12.8
44
131
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.5
12.6
31
72
N085, M318,
ICD-10 Finland
+∞
12.5
12
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
12.5
12
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
12.3
121
622
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.5
12.3
30
69
R03AC13
ATC
formoterol; inhalant
3.5
12.2
43
130
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.7
11.7
22
40
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
11.6
44
139
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
23.5
11.6
16
7
M05BX04
ATC
denosumab; parenteral
3.4
11.6
42
129
WX892
NOMESCO Finland
Monitored bed care
2.9
11.6
56
205
XW000
NOMESCO Finland
Bone marrow biopsy
3.9
11.6
35
95
Z94.0
ICD-10 Finland
Kidney transplant status
14.0
11.5
19
14
297, ,
Kela drug reimbursment
+∞
11.5
11
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
11.5
11
*
N06AA09
ATC
amitriptyline; systemic
2.7
11.5
64
253
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
11.5
63
247
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.0
11.4
52
184
TK800
NOMESCO Finland
Hemodialysis
8.6
11.4
24
29
WW200
NOMESCO Finland
Immunization
5.3
11.4
23
45
S97
ICPC
Chronic ulcer skin
3.1
11.2
48
164
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
5.9
11.1
20
35
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.0
11.1
50
176
J01FA06
ATC
roxithromycin; oral
1.9
11.1
221
1457
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.4
10.9
40
124
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.6
10.9
37
109
SPAT1255
SPAT
Intravenous administration of medicine
3.3
10.8
41
130
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
10.7
83
384
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
22.0
10.7
15
7
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
10.7
162
974
UDM02
NOMESCO Finland
Sinoscopy
5.2
10.6
22
44
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.8
10.6
32
87
3028
Kela drug reimbursment
Mepolizumab
112.1
10.5
11
*
R03DX09
ATC
mepolizumab; parenteral
+∞
10.4
10
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
10.4
10
*
M13.9
ICD-10 Finland
Arthritis, unspecified
3.0
10.4
48
171
A12AA04
ATC
calcium carbonate; oral
8.5
10.4
22
27
R03BA01
ATC
beclometasone; inhalant
2.3
10.4
86
410
A01AB09
ATC
miconazole; local oral
2.6
10.4
61
248
127
Kela drug reimbursment
Transplant complication
8.7
10.1
21
25
C07AB07
ATC
bisoprolol; oral
1.8
10.1
258
1822
G58.7
ICD-10 Finland
Mononeuritis multiplex
40.9
10.0
12
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.1
9.9
27
68
AA1AD
NOMESCO Finland
CT of head and brain
1.9
9.9
144
851
J47
ICD-10 Finland
Bronchiectasis
4.8
9.9
22
47
DHA10
NOMESCO Finland
Biopsy of cavity of nose
10.9
9.8
18
17
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
20.5
9.8
14
7
M05BA07
ATC
risedronic acid; oral
4.0
9.8
28
73
R06AE07
ATC
cetirizine; oral
1.8
9.8
233
1607
R03DA04
ATC
theophylline; systemic, rectal
3.0
9.7
43
150
R02
ICPC
Shortness of breath/dyspnoea
2.3
9.6
78
368
R03BA08
ATC
ciclesonide; inhalant
2.6
9.6
56
227
A07AA02
ATC
nystatin; oral
3.0
9.5
44
157
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
9.5
106
569
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
9.5
50
192
L88
ICPC
Rheumatoid/seropositive arthritis
3.9
9.4
28
75
L95.0
ICD-10 Finland
Livedoid vasculitis
101.8
9.4
10
*
DHB20
NOMESCO Finland
Polypectomy of internal nose
8.3
9.4
20
25
H26.3
ICD-10 Finland
Drug-induced cataract
12.6
9.4
16
13
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
9.4
9
*
L95.8
ICD-10 Finland
Other vasculitis limited to skin
22.2
9.4
13
6
B01AA03
ATC
warfarin; systemic
2.1
9.4
107
579
WZC30
NOMESCO Finland
Teaching
2.2
9.3
88
442
J01DC02
ATC
cefuroxime; systemic
3.2
9.3
38
126
KCV04
NOMESCO Finland
Distension of bladder with fluid
14.0
9.2
15
11
R06.0
ICD-10 Finland
Dyspnoea
1.9
9.2
147
894
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
11.7
9.1
16
14
A12BA01
ATC
potassium chloride; oral
3.1
9.1
38
128
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.2
9.1
24
59
N03AX12
ATC
[U] gabapentin; oral
2.1
9.0
95
498
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
4.3
9.0
23
55
R03AK07
ATC
formoterol and budesonide; inhalant
2.0
9.0
111
617
M81.4
ICD-10 Finland
Drug-induced osteoporosis
24.5
8.9
12
5
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
8.9
112
627
N18.0
ICD-10 Finland
End-stage renal disease
11.0
8.8
16
15
R03AC03
ATC
terbutaline; inhalant
2.2
8.7
80
398
J01DB01
ATC
cefalexin; oral
2.0
8.6
434
3674
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
11.8
8.6
15
13
A02BC05
ATC
esomeprazole; systemic
1.7
8.6
211
1455
N30.0
ICD-10 Finland
Acute cystitis
2.1
8.6
94
500
JN4AD
NOMESCO Finland
Body CT examination
2.5
8.6
57
246
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
8.5
94
501
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
28.0
8.5
11
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
20.4
8.5
12
6
A10AB05
ATC
insulin aspart; parenteral
2.6
8.4
52
216
R03DC01
ATC
zafirlukast; oral
5.0
8.4
18
37
UJF30
NOMESCO Finland
Ileoscopy through colon
2.4
8.4
58
255
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
8.4
8
*
4476A
ICD-9 Finland
Other disorders of arteries and arterioles, Arteritis, unspecified
+∞
8.4
8
*
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
8.4
8
*
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
8.3
28
82
ZX112
NOMESCO Finland
Subcutaneous
4.5
8.2
20
46
UJF32
NOMESCO Finland
Coloscopy
1.9
8.2
134
816
A12AA12
ATC
[U] calcium acetate
33.9
8.1
10
*
R01AD01
ATC
beclometasone; nasal
2.1
8.1
87
459
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
8.1
63
292
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
8.0
29
89
UKC02
NOMESCO Finland
Cystoscopy
2.1
8.0
79
403
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
8.0
130
791
N05CD07
ATC
temazepam; oral
2.2
8.0
72
355
J01MA06
ATC
norfloxacin; oral
2.1
7.9
80
412
B03XA02
ATC
darbepoetin alfa; parenteral
6.3
7.9
20
33
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
7.9
79
405
Z3231
NOMESCO Finland
Registered nurse
1.8
7.9
155
998
DPA30
NOMESCO Finland
Sphenotomy
11.0
7.8
14
13
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.4
7.8
55
244
M31.6
ICD-10 Finland
Other giant cell arteritis
45.7
7.7
9
*
E0000UV, ,
ATC
1.7
7.7
219
1562
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.3
7.6
29
92
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
9.0
7.6
15
17
Z2446
NOMESCO Finland
Social worker
2.4
7.5
52
228
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.3
7.5
19
45
R60.0
ICD-10 Finland
Localized oedema
2.2
7.5
68
335
ZXD05
NOMESCO Finland
Urgent procedure
1.7
7.5
167
1112
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
6.1
7.4
19
32
J01EA01
ATC
trimethoprim; systemic
1.8
7.4
146
938
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.0
7.4
32
110
N06AX21
ATC
duloxetine; oral
2.1
7.4
69
345
J01FA10
ATC
azithromycin; systemic
1.7
7.3
298
2317
L04AD02
ATC
tacrolimus; systemic
11.1
7.3
13
12
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
9.6
7.3
14
15
M79.7
ICD-10 Finland
Fibromyalgia
3.9
7.3
21
55
JN6JR
NOMESCO Finland
Extensive PET-CT of whole body metabolism (crown to foot)
+∞
7.3
7
*
J01AA02
ATC
doxycycline; systemic
1.7
7.3
387
3226
SPAT1167
SPAT
Insertion of urinary catheter
4.0
7.2
20
51
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.7
7.2
23
65
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.2
140
895
ZXD20
NOMESCO Finland
Day surgery
2.1
7.2
72
369
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.2
189
1314
I40.9
ICD-10 Finland
Acute myocarditis, unspecified
20.3
7.2
10
5
J01DA06
ATC
[U] cefuroxime
2.0
7.1
83
450
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
7.1
276
2115
SPAT1301
SPAT
No procedures
1.7
7.1
166
1117
N02AA05
ATC
oxycodone; systemic
1.9
7.1
95
541
Z49.0
ICD-10 Finland
Preparatory care for dialysis
10.2
7.1
13
13
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
10.2
7.1
13
13
R03AK11
ATC
formoterol and fluticasone; inhalant
4.0
7.0
20
52
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.2
7.0
28
92
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.1
6.9
19
48
M01AH01
ATC
celecoxib; oral
1.9
6.9
92
522
1XC02, ,
NOMESCO Finland
14.0
6.9
11
8
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.4
6.9
24
72
A07EC01
ATC
sulfasalazine; oral, rectal
2.5
6.9
44
186
A02BC03
ATC
lansoprazole; oral
1.7
6.9
151
997
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
6.9
56
264
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.2
6.8
27
88
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.3
6.8
53
246
318
Kela drug reimbursment
Teriparatide
17.0
6.8
10
6
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.7
6.8
37
145
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.1
6.8
28
94
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.0
6.7
30
105
J31.0
ICD-10 Finland
Chronic rhinitis
2.3
6.7
50
228
B07.9
ICD-10 Finland
Verruca simplex
3.4
6.6
23
69
L52
ICD-10 Finland
Erythema nodosum
12.4
6.6
11
9
M05BA01
ATC
etidronic acid; systemic
12.4
6.6
11
9
SPAT1360
SPAT
Extensive global examination
2.6
6.6
38
153
UDC00
NOMESCO Finland
Ear microscopy
2.3
6.6
48
216
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
6.5
250
1897
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
6.5
47
211
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
6.5
88
503
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.4
186
1317
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.1
6.4
17
42
M79.6
ICD-10 Finland
Pain in limb
1.6
6.4
210
1535
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.5
6.3
21
61
C08CA05
ATC
nifedipine; systemic
2.6
6.3
36
144
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
11.2
6.3
11
10
137
Kela drug reimbursment
Uraemia requiring dialysis
9.4
6.3
12
13
A28
ICPC
Limited function/disability NOS
1.9
6.3
89
515
TK810
NOMESCO Finland
Hemofiltration
18.3
6.3
9
5
S18
ICPC
Laceration/cut
1.6
6.3
224
1667
4460B
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa[POLYARTERITIS NODOSA CUM INFILTRATIONE PULMONUM]
+∞
6.3
6
*
M30
ICD-10 Finland
Polyarteritis nodosa and related conditions
+∞
6.3
6
*
M05.2
ICD-10 Finland
Rheumatoid vasculitis
+∞
6.3
6
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
6.3
6
*
N085, M319,
ICD-10 Finland
+∞
6.3
6
*
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
6.3
6
*
I77.9
ICD-10 Finland
Disorder of arteries and arterioles, unspecified
+∞
6.3
6
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.8
6.2
19
52
ZXE00
NOMESCO Finland
One hour or less
1.6
6.2
202
1468
J01FA15
ATC
telithromycin; oral
2.2
6.2
52
248
R01AD09
ATC
mometasone; nasal
1.6
6.2
226
1688
SPAT1262
SPAT
Handing over of treatment supplies
1.9
6.2
90
525
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
6.2
85
487
C07AB02
ATC
metoprolol; systemic
1.8
6.1
104
637
J32.8
ICD-10 Finland
Other chronic sinusitis
12.7
6.1
10
8
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.5
6.1
20
58
L17
ICPC
Foot/toe symptom/complaint
1.7
6.1
146
985
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
6.0
151
1029
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
109
62
21.85
138.26
2.5
1.1
46.67
—
titre
—
6
0
104
99
12.81
98.40
4.5
1.2
10.33
—
iu/ml
—
19
0
138
290
6.08
65.72
5.2
3.0
9.46
10.17
g/l
1.01
131
264
80
121
7.60
52.03
1.4
1.1
0.24
3.41
u/ml
—
5
8
105
235
5.32
45.69
2.1
1.7
1.04
1.43
g/l
1.20
100
215
70
109
7.24
44.15
3.2
1.3
—
—
—
0
0
100
245
4.79
38.79
2.1
1.2
270.18
250.57
u/ml
0.06
95
224
348
1929
3.32
38.50
16.4
5.6
3.14
2.82
%
0.71
340
1813
355
1998
3.33
38.13
16.5
5.7
24.33
28.38
%
11.08
348
1888
350
1967
3.28
37.41
15.5
5.5
60.89
56.86
%
8.48
343
1860
41
42
10.49
36.08
1.5
1.1
—
—
—
0
0
51
71
7.84
35.36
6.8
7.5
439.33
131.45
iu/ml
—
9
11
105
287
4.31
35.27
2.1
2.7
64.84
66.94
g/l
1.69
95
258
119
376
3.79
32.51
2.9
1.8
305.05
377.78
nmol/l
3.55
113
345
144
519
3.43
32.14
9.6
5.6
1.06
1.08
mmol/l
0.19
136
477
110
340
3.82
30.93
10.1
7.3
10.73
9.33
mmol/l
1.03
105
324
124
422
3.53
30.12
4.0
4.4
238.75
259.64
u/l
0.48
118
404
48
75
6.94
29.94
5.4
3.1
61.04
57.57
%
0.81
48
75
378
2391
3.01
29.65
17.8
8.7
4.99
4.06
e9/l
7.36
366
2103
331
1957
2.83
29.45
11.7
6.7
1.21
1.22
mmol/l
1.32
280
1674
46
71
7.00
29.01
4.8
2.9
4.87
4.45
e9/l
0.48
46
71
309
1787
2.74
28.32
9.7
5.9
1.21
1.22
mmol/l
0.72
297
1623
186
854
2.81
26.55
5.0
2.5
4.61
5.61
e6/l
0.35
178
766
66
161
4.54
25.36
1.3
2.1
36.25
38.86
u/l
0.46
61
140
284
1638
2.57
25.21
3.2
2.3
81.03
76.21
nmol/l
2.06
273
1460
284
1643
2.56
24.97
8.3
4.6
33.40
35.73
g/l
7.66
272
1537
63
150
4.63
24.94
2.4
1.9
0.62
3.57
ug/l
0.91
58
133
258
1436
2.55
24.50
6.0
3.1
—
—
—
0
0
41
70
6.26
23.42
1.3
1.2
—
—
—
0
0
54
120
4.90
23.20
1.8
1.5
0.15
0.16
iu/ml
0.01
11
20
219
1160
2.51
22.72
3.2
2.0
175.73
324.21
u/l
0.94
205
1090
54
124
4.73
22.30
2.9
2.8
—
—
—
0
0
44
85
5.55
22.12
1.6
1.1
1.39
2.56
u/ml
—
8
7
129
533
2.87
21.98
3.9
2.3
20.59
22.75
%
1.09
114
468
29
36
8.46
21.96
2.1
1.6
—
—
—
0
0
44
87
5.42
21.56
1.6
1.1
3.98
5.04
u/ml
—
8
8
34
52
6.92
21.54
1.6
1.5
—
—
—
0
0
140
613
2.74
21.30
3.5
2.3
11.44
13.16
umol/l
2.27
133
577
226
1244
2.42
21.23
5.9
3.1
28.32
106.26
e6/l
0.83
199
957
85
283
3.38
20.94
5.0
4.0
1.79
1.67
mmol/l
0.10
69
200
39
72
5.77
20.55
1.5
1.5
—
—
—
0
0
144
652
2.66
20.41
2.5
1.8
—
—
—
0
0
33
52
6.70
20.33
1.4
1.5
—
—
—
0
0
112
449
2.89
20.03
5.1
2.8
1.87
1.81
%
0.22
104
415
130
568
2.71
19.71
3.7
2.3
2.28
2.36
g/l
0.78
122
528
35
62
5.97
19.23
1.4
1.5
—
—
—
0
0
41
85
5.14
19.04
1.4
1.4
313.29
276.19
u/ml
0.21
27
42
133
598
2.63
18.98
3.5
3.8
0.79
0.82
mmol/l
2.13
128
555
44
99
4.76
18.58
2.3
4.2
51.49
122.60
mg/l
0.52
32
75
44
99
4.76
18.58
2.3
4.3
31.32
61.55
mg/l
0.46
31
75
45
104
4.63
18.39
2.2
1.6
—
—
—
0
0
41
88
4.96
18.30
1.5
1.4
—
—
—
0
0
57
160
3.87
18.05
1.7
2.2
1.62
1.45
g/l
0.58
47
144
43
98
4.69
17.87
2.3
4.2
1.96
2.33
ratio
—
5
14
45
108
4.46
17.55
2.1
1.5
—
—
—
0
0
36
74
5.15
16.86
2.3
1.6
—
—
—
0
0
39
86
4.81
16.85
1.7
1.4
—
—
—
0
0
83
310
2.99
16.71
6.6
3.9
109.58
76.27
ng/l
1.98
74
280
404
3036
2.37
16.30
11.3
3.7
15.91
11.69
mm/h
5.30
391
2784
77
281
3.03
16.13
2.0
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
41
98
4.45
16.06
3.8
2.6
0.39
0.33
u/ml
0.40
27
52
196
1120
2.19
15.85
5.8
3.0
0.32
0.50
e6/l
0.84
171
837
166
890
2.26
15.68
1.8
1.8
1.21
1.26
mg/l
0.08
134
694
282
1858
2.10
15.65
16.2
12.7
1.23
1.23
inr
0.00
106
550
161
857
2.26
15.44
2.0
1.4
2.38
2.29
g/l
0.28
123
518
336
2391
2.10
14.85
6.8
4.7
6.90
6.66
mmol/l
0.79
325
2210
192
1127
2.10
14.18
4.0
3.1
2139.79
1340.95
ng/l
0.49
178
963
186
1094
2.08
13.54
6.5
3.7
0.00
0.00
estimate
-0.00
96
376
120
594
2.32
13.48
2.5
2.0
29.47
29.57
s
0.08
115
580
293
2034
1.98
13.27
6.2
3.6
0.00
0.00
estimate
0.50
103
410
293
2037
1.98
13.18
8.1
4.9
0.00
0.00
estimate
-0.00
100
383
295
2061
1.97
13.02
6.2
3.6
0.00
0.01
estimate
0.50
97
374
172
997
2.07
12.93
3.2
2.6
1116.97
6805.66
umol/l
2.79
151
873
27
55
5.12
12.76
1.7
1.1
6.73
1.33
u/ml
0.84
11
18
33
80
4.33
12.69
1.5
1.4
114.88
102.42
u/ml
—
8
16
399
3128
2.10
12.33
14.7
7.0
75.84
79.98
u/l
1.22
390
2914
211
1341
1.95
12.06
3.4
3.2
2.31
2.36
mmol/l
3.76
196
1177
28
62
4.71
12.03
1.7
1.4
—
—
—
0
0
32
79
4.25
12.02
2.7
2.3
16.67
16.21
%
0.23
25
36
97
464
2.33
11.68
2.3
1.8
—
—
—
0
0
232
1535
1.91
11.65
6.1
3.6
35.39
41.70
ng/l
0.41
173
1051
196
1238
1.92
11.24
5.5
3.1
7.26
7.55
mmol/l
0.35
170
1051
293
2111
1.86
11.09
7.5
6.0
11.72
11.16
umol/l
0.19
287
1998
26
58
4.66
11.07
1.7
1.2
3.33
3.62
u/ml
0.09
12
24
40
124
3.41
10.91
2.8
2.2
—
—
—
0
0
180
1117
1.92
10.81
5.6
3.2
351.49
175.72
mg/l
0.28
134
736
125
683
2.09
10.77
1.4
1.2
36.82
33.83
iu/ml
0.12
51
220
23
48
4.96
10.58
1.9
1.5
—
—
—
0
0
93
456
2.26
10.51
2.3
1.7
—
—
—
0
0
186
1180
1.89
10.36
6.9
3.8
18.54
10.94
mg/mmol
0.89
135
749
257
1808
1.82
10.22
4.3
2.6
213.92
112.17
ug/l
2.04
251
1661
36
109
3.47
10.18
1.9
2.6
0.03
1.26
g/l
1.79
31
95
83
395
2.30
10.05
6.9
3.8
1.63
1.84
mmol/l
0.25
77
320
21
26
8.36
9.91
1.8
1.2
0.39
0.13
u/ml
0.69
15
16
203
1341
1.83
9.84
3.9
3.2
45.76
33.14
u/l
0.48
186
1277
31
87
3.72
9.80
4.1
3.5
4.89
4.96
kpa
0.18
31
87
118
653
2.04
9.73
1.4
1.2
14.52
13.15
u/ml
0.07
43
259
88
438
2.21
9.55
6.6
8.3
10.89
12.29
kpa
2.38
81
422
352
2759
1.82
9.41
7.0
4.3
7978.53
1583.82
e6/l
0.44
15
45
76
358
2.31
9.40
2.2
2.3
0.20
0.22
g/l
0.83
71
334
126
723
1.97
9.36
1.8
1.7
1234.73
1203.56
nmol/l
0.13
104
547
162
1013
1.86
9.27
3.2
2.0
3.12
3.11
mg/l
0.01
152
868
19
23
8.52
9.14
1.5
1.1
—
—
—
0
0
19
23
8.52
9.14
1.5
1.4
—
—
—
0
0
20
43
4.79
8.89
2.4
1.9
—
—
—
0
0
71
334
2.30
8.80
5.5
7.0
1.33
1.39
mmol/l
0.29
71
328
17
19
9.20
8.59
1.5
1.4
—
—
—
0
0
27
76
3.69
8.51
2.4
1.6
—
—
—
0
0
27
76
3.69
8.51
2.4
1.6
—
—
—
0
0
85
439
2.11
8.36
6.7
8.3
1.10
1.20
mmol/l
0.07
73
350
17
20
8.74
8.36
1.5
1.4
—
—
—
0
0
60
268
2.40
8.35
5.6
6.6
24.75
24.77
mmol/l
0.02
60
268
80
406
2.14
8.23
4.4
3.2
—
—
—
0
0
18
24
7.72
8.22
1.1
1.1
64.52
29.36
mg/l
0.72
12
19
187
1258
1.75
8.21
2.9
2.4
54.15
62.32
u/l
0.94
173
1174
35
120
3.05
8.13
2.3
1.5
—
—
—
0
0
14
12
11.94
8.11
2.0
1.3
—
—
—
0
0
30
95
3.29
7.93
1.3
1.6
—
—
—
0
0
20
48
4.29
7.80
2.4
1.8
—
—
—
0
0
11
6
18.68
7.63
1.4
1.3
—
—
—
0
0
222
1596
1.67
7.48
6.4
3.7
—
—
—
0
0
17
38
4.59
7.22
3.1
2.0
—
—
—
0
0
18
31
5.97
6.97
1.8
2.8
—
—
—
0
0
18
31
5.97
6.97
1.6
2.6
—
—
—
0
0
14
17
8.42
6.86
1.1
1.2
—
—
—
0
0
16
24
6.84
6.86
1.0
1.0
—
—
—
0
0
18
32
5.78
6.81
1.7
1.4
—
—
—
0
0
50
228
2.32
6.65
4.9
2.4
0.32
0.16
e6/l
0.37
50
220
17
41
4.25
6.59
2.6
1.6
—
—
—
0
0
17
41
4.25
6.59
2.6
1.6
—
—
—
0
0
17
41
4.25
6.59
2.6
1.6
—
—
—
0
0
15
23
6.68
6.37
1.4
1.1
—
—
—
0
0
10
8
12.71
6.10
1.2
1.0
—
—
—
0
0
14
21
6.81
6.07
1.0
1.0
1.09
1.11
u/l
—
8
15
16
40
4.09
5.93
1.0
1.1
—
—
—
0
0
82
471
1.88
5.92
7.9
6.8
103.50
104.08
mmol/l
0.68
82
471
10
9
11.29
5.81
1.6
3.0
—
—
—
0
0
118
765
1.70
5.65
4.2
3.7
546.74
294.03
ng/l
0.42
90
595
16
42
3.90
5.57
1.0
1.1
—
—
—
0
0
19
57
3.42
5.49
1.6
1.1
—
—
—
0
0
48
234
2.16
5.46
1.7
1.4
—
—
—
0
0
12
17
7.19
5.46
3.1
1.8
—
—
—
0
0
80
470
1.83
5.37
2.4
2.8
11.15
8.34
umol/l
0.27
71
410
34
144
2.45
5.34
2.0
1.5
—
—
—
0
0
36
157
2.39
5.32
2.9
1.8
—
—
—
0
0
10
11
9.24
5.30
1.0
1.0
—
—
—
0
0
29
115
2.61
5.21
1.4
1.2
—
—
—
0
0
247
1937
1.51
5.19
3.3
2.5
—
—
—
0
0
16
36
4.55
5.09
2.7
2.1
—
—
—
0
0
11
16
6.99
4.97
1.0
1.1
—
—
—
0
0
12
20
6.11
4.93
1.2
1.1
114.26
196.13
iu/ml
0.71
12
20
21
72
3.00
4.93
3.7
3.2
0.69
0.91
nmol/l
0.94
14
57
14
29
4.93
4.84
1.1
1.1
—
—
—
0
0
14
29
4.93
4.84
1.1
1.1
—
—
—
0
0
11
17
6.58
4.79
3.3
1.8
—
—
—
0
0
11
17
6.58
4.79
3.3
1.8
—
—
—
0
0
16
47
3.48
4.78
1.0
1.1
—
—
—
0
0
14
30
4.76
4.71
1.1
1.1
—
—
—
0
0
14
30
4.76
4.71
1.1
1.1
—
—
—
0
0
14
30
4.76
4.71
1.1
1.1
—
—
—
0
0
11
18
6.22
4.62
1.5
2.4
1735.91
839.89
u/ml
0.64
11
18
28
118
2.45
4.47
1.5
1.3
—
—
—
0
0
16
50
3.27
4.37
1.4
1.4
—
—
—
0
0
55
307
1.88
4.34
3.7
3.3
231.58
197.45
ng/l
0.21
50
276
205
1593
1.47
4.28
2.2
1.9
91.67
94.98
pmol/l
0.56
120
811
14
34
4.20
4.23
1.0
1.1
—
—
—
0
0
11
21
5.32
4.16
1.1
1.1
1.10
1.05
ratio
—
5
7
458
4187
1.67
4.12
33.6
13.0
23.90
22.88
mg/l
0.27
422
3281
22
87
2.59
4.01
1.8
1.4
—
—
—
0
0
22
87
2.59
4.01
1.8
1.4
—
—
—
0
0
31
145
2.21
3.95
1.9
1.7
—
—
—
0
0
16
54
3.02
3.88
1.9
1.5
—
—
—
0
0
16
54
3.02
3.88
1.9
1.5
—
—
—
0
0
96
647
1.59
3.87
4.6
2.8
2.70
2.72
e6/l
0.01
56
354
8
11
7.36
3.87
1.4
1.5
—
—
—
0
0
9
15
6.08
3.83
3.0
6.1
—
—
—
0
0
13
33
4.01
3.82
1.5
1.4
132387.57
65937.78
e6/l
—
7
18
6
5
12.11
3.77
1.7
1.2
—
—
—
0
0
11
24
4.66
3.76
3.3
1.6
—
—
—
0
0
11
24
4.66
3.76
3.3
1.6
—
—
—
0
0
23
97
2.43
3.70
2.3
2.3
46.89
66.22
ug/min
0.39
18
60
8
12
6.75
3.68
1.1
1.0
91.38
98.00
%
—
8
12
17
62
2.80
3.62
1.3
1.1
—
—
—
0
0
13
35
3.78
3.61
1.2
1.2
—
—
—
0
0
7
11
6.43
3.19
1.0
1.0
1699.43
1282.09
miu/ml
—
7
11
96
676
1.51
3.17
4.6
2.6
0.65
1.01
e6/l
0.77
57
379
50
302
1.72
3.09
4.7
2.6
57.04
64.62
ml/min/173m2
0.69
27
125
6
8
7.57
3.06
1.2
1.4
—
—
—
0
0
7
12
5.89
3.03
1.0
1.3
—
—
—
0
0
61
392
1.63
2.99
2.2
2.3
32.02
155.98
u/l
0.50
53
331
129
974
1.43
2.99
3.1
2.1
—
—
—
0
0
5
5
10.08
2.98
1.0
1.0
—
—
—
0
0
12
37
3.29
2.95
1.1
1.1
—
—
—
0
0
12
37
3.29
2.95
1.1
1.1
—
—
—
0
0
9
22
4.14
2.89
1.2
1.1
—
—
—
0
0
10
27
3.75
2.89
1.4
1.0
—
—
—
0
0
23
110
2.14
2.83
1.1
1.3
—
—
—
0
0
38
218
1.80
2.81
2.1
1.6
—
—
—
0
0
21
97
2.21
2.80
2.0
1.3
—
—
—
0
0
17
364
0.45
2.80
1.6
1.6
—
—
—
0
0
23
111
2.12
2.77
1.0
1.1
—
—
—
0
0
10
29
3.49
2.70
1.7
2.2
931.70
503.12
ml
—
10
17
9
24
3.80
2.68
1.7
1.3
—
—
—
0
0
9
24
3.80
2.68
1.7
1.3
—
—
—
0
0
15
61
2.50
2.64
1.3
1.2
—
—
—
0
0
51
324
1.63
2.64
4.2
2.2
5.63
6.83
ug/l
0.31
38
291
14
55
2.59
2.63
1.1
1.1
—
—
—
0
0
11
36
3.10
2.58
1.1
1.3
—
—
—
0
0
5
7
7.20
2.55
1.0
4.6
—
—
—
0
0
96
707
1.44
2.53
2.7
2.8
2.45
2.45
mmol/l
0.04
86
618
119
924
1.37
2.31
1.9
1.5
18.90
20.91
nmol/l
1.04
107
803
12
47
2.59
2.28
2.4
2.3
31.25
32.62
pg
0.35
12
47
8
24
3.37
2.18
5.0
3.7
—
—
—
0
0
19
95
2.04
2.13
2.4
1.4
—
—
—
0
0
7
20
3.53
2.06
1.0
1.0
—
—
—
0
0
7
21
3.36
1.97
1.7
1.3
—
—
—
0
0
7
21
3.36
1.97
1.7
1.3
—
—
—
0
0
115
910
1.34
1.97
6.7
3.7
1.02
1.02
kg/l
0.34
17
137
303
2720
1.26
1.93
3.8
3.1
59.43
46.60
u/l
1.47
282
2552
7
22
3.21
1.88
2.3
2.1
45.63
81.10
ug/l
—
7
22
7
22
3.21
1.88
1.0
1.5
—
—
—
0
0
7
22
3.21
1.88
1.0
1.5
—
—
—
0
0
102
802
1.34
1.82
1.8
1.7
446.27
7385969.68
pmol/l
0.50
89
677
15
75
2.03
1.71
1.4
1.4
—
—
—
0
0
6
20
3.02
1.58
1.2
1.1
91.00
73.90
u/l
—
6
20
6
20
3.02
1.58
1.2
1.1
27.33
16.44
u/l
—
6
20
345
3186
1.24
1.54
4.4
4.0
15.05
14.72
pmol/l
1.54
319
2873
5
15
3.35
1.52
1.2
1.1
—
—
—
0
0
11
51
2.18
1.51
2.7
1.5
—
—
—
0
0
11
51
2.18
1.51
2.7
1.5
—
—
—
0
0
6
21
2.88
1.51
1.3
1.5
—
—
—
0
0
11
52
2.14
1.45
2.7
1.5
—
—
—
0
0
11
52
2.14
1.45
2.7
1.5
—
—
—
0
0
11
52
2.14
1.45
2.7
1.5
—
—
—
0
0
5
16
3.14
1.44
1.8
2.3
—
—
—
0
0
5
16
3.14
1.44
1.2
4.1
2.38
2.20
ug/l
—
5
16
5
16
3.14
1.44
2.8
2.3
46180.00
33625.31
ug/l
—
5
16
5
16
3.14
1.44
1.0
1.1
—
—
—
0
0
5
16
3.14
1.44
1.2
1.1
—
—
—
0
0
6
22
2.75
1.44
1.2
1.4
—
—
—
0
0
10
47
2.15
1.34
6.1
3.4
—
—
—
0
0
53
396
1.38
1.34
3.1
3.9
10.85
39.85
ug/l
0.74
37
323
6
24
2.52
1.30
1.2
1.4
85.00
72.63
umol/l
—
6
24
10
48
2.10
1.28
1.2
1.1
1.70
1.43
g/l
—
10
42
99
817
1.26
1.25
1.8
1.5
—
—
—
0
0
8
37
2.18
1.22
1.3
1.4
—
—
—
0
0
13
73
1.80
1.11
1.0
1.1
—
15.78
—
0
5
10
52
1.94
1.06
2.9
1.5
—
—
—
0
0
295
2744
1.17
1.01
3.8
3.1
—
—
—
0
0
403
3847
1.20
1.00
26.6
12.1
79.30
82.47
ml/min/173m2
1.64
354
3143
115
989
1.21
1.00
1.3
1.3
1.56
1.41
u/ml
0.06
22
268
9
49
1.85
0.99
1.2
1.0
—
—
—
0
0
5
23
2.18
0.98
1.4
1.3
5.24
6.70
mmol/l
—
5
23
121
1051
1.20
0.95
1.7
1.7
1.59
1.37
mmol/l
1.13
107
892
11
62
1.79
0.95
1.2
1.2
—
—
—
0
0
6
29
2.08
0.89
1.2
1.4
—
26.80
—
0
5
12
71
1.71
0.89
1.0
1.1
—
—
—
0
0
13
79
1.66
0.88
1.2
1.8
4.79
4.46
mmol/24h
0.17
13
68
6
32
1.88
0.82
1.8
1.9
—
—
—
0
0
6
32
1.88
0.82
1.2
1.4
1.18
1.26
promille
—
6
23
9
55
1.65
0.74
1.7
1.3
0.51
0.51
nmol/l
—
9
49
389
3740
1.15
0.72
6.9
5.6
40.25
39.79
mmol/mol
0.39
367
3484
18
127
1.43
0.69
1.3
1.1
—
—
—
0
0
7
119
0.58
0.68
1.4
1.5
—
—
—
0
0
18
128
1.42
0.66
1.3
1.1
—
—
—
0
0
17
234
0.72
0.63
1.5
1.5
—
—
—
0
0
396
3827
1.14
0.62
5.1
4.7
1.97
1.90
mu/l
0.44
371
3473
0
20
0.00
0.60
0.0
1.6
—
—
—
0
0
17
123
1.39
0.58
1.8
1.4
—
—
—
0
0
6
41
1.47
0.50
2.7
2.1
13.60
13.30
%
—
6
41
24
295
0.80
0.43
1.8
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
331.90
—
0
10
9
121
0.74
0.35
1.2
1.5
—
—
—
0
0
9
121
0.74
0.35
1.2
1.5
—
—
—
0
0
9
121
0.74
0.35
1.2
1.5
—
—
—
0
0
9
121
0.74
0.35
1.2
1.5
—
—
—
0
0
5
80
0.62
0.35
3.6
1.8
212.80
238.53
pmol/l
—
5
73
19
233
0.81
0.35
1.7
1.9
—
—
—
0
0
385
3932
0.92
0.33
5.2
4.4
5.88
5.94
mmol/l
0.34
356
3569
27
230
1.18
0.31
1.2
1.3
—
—
—
0
0
58
640
0.89
0.31
2.5
2.9
0.65
0.74
ug/l
0.63
39
415
8
106
0.75
0.29
2.0
1.6
—
—
—
0
0
8
109
0.73
0.29
1.4
1.2
—
—
—
0
0
14
112
1.26
0.28
1.7
1.5
—
—
—
0
0
82
876
0.92
0.24
4.2
4.3
21.27
21.43
%
0.03
41
412
5
39
1.28
0.23
1.2
1.2
—
—
—
0
0
11
135
0.81
0.22
1.4
1.5
—
—
—
0
0
54
498
1.09
0.22
4.2
4.3
33.90
31.91
%
0.67
42
336
18
154
1.17
0.21
2.4
1.9
—
—
—
0
0
114
1092
1.06
0.18
4.4
4.8
2.28
2.43
ug/l
0.14
102
983
51
476
1.08
0.17
10.4
6.3
—
—
—
0
0
9
78
1.16
0.15
2.4
1.8
—
—
—
0
0
18
159
1.14
0.15
1.2
2.4
13224.29
4621.97
u/l
—
9
68
5
44
1.14
0.10
1.0
1.8
13.04
16.60
ug/l
—
5
44
5
63
0.79
0.08
1.8
1.5
—
—
—
0
0
387
3845
1.02
0.07
4.3
3.9
1.37
1.28
mmol/l
1.53
361
3532
51
495
1.03
0.05
1.5
1.7
1.48
1.47
%
0.06
44
434
31
297
1.05
0.05
1.2
1.2
30.71
147.71
iu/ml
5.04
12
121
51
525
0.97
0.05
2.5
2.3
—
—
—
0
0
398
3999
0.98
0.05
4.7
4.3
4.55
4.65
mmol/l
1.20
376
3720
15
140
1.07
0.04
2.7
1.5
336.20
298.70
mu/l
0.28
15
127
13
121
1.08
0.03
1.2
1.4
340.60
289.02
ug/g
—
5
73
396
3974
0.99
0.03
4.7
4.2
1.47
1.47
mmol/l
0.02
372
3673
469
4680
1.02
0.02
44.3
19.4
39.81
40.14
%
0.75
448
4400
13
135
0.96
0.00
1.7
1.3
—
—
—
0
0
48
484
0.99
0.00
2.2
2.1
—
—
—
0
0
67
673
0.99
0.00
1.6
1.5
—
—
—
0
0
23
231
1.00
0.00
1.0
1.0
—
—
—
0
0
409
4086
1.00
0.00
5.0
4.8
2.61
2.75
mmol/l
2.29
385
3768
0
7
0.00
-0.00
0.0
2.4
—
37.14
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
55.46
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
22.60
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_POLYARTERETAL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_POLYARTERETAL | 2.265 [1.92, 2.68] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.11 |
During the follow-up period (1.1.1998 — 31.12.2019), 770 out of 2094 females with M13_POLYARTERETAL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_POLYARTERETAL | 2.27 [1.8, 2.86] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 372 out of 1721 males with M13_POLYARTERETAL died.
Mortality risk
Mortality risk for people of age
years, who have M13_POLYARTERETAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.176% | 0.466% |
| 5 | 1.242% | 2.493% |
| 10 | 3.117% | 6.549% |
| 15 | 6.191% | 12.498% |
| 20 | 10.063% | 20.251% |
Relationships between endpoints
↥Index endpoint: M13_POLYARTERETAL – Polyarteritis nodosa and related conditions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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