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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Juvenile polyarteritis

M13_JUVEPOLYNOD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M30.2
  • Cause of death: ICD-10 M30.2

2 out of 7 registries used, show all original rules.

5

4. Check minimum number of events

None

5

5. Include endpoints

None

5

6. Filter based on genotype QC (FinnGen only)

5

Control definitions (FinnGen only)

Control exclude
M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M30
Name in latin
Polyarteritis nodosa juvenilis

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 85 55 30
Only index persons 60 35 25
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 61.30 20.15
Only index persons 21.29 22.44 19.69

-FinnGen-

Key figures

All Female Male
Number of individuals 5 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 23.26 - -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(42870588) Differential panel, method unspecified - Blood
5
7
+∞
3.64
7.6
2.3
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
5
11
+∞
2.90
11.4
1.9
%
0.6
0.3
—
5
11
(3006504) Eosinophils/100 leukocytes in Blood
5
13
+∞
2.61
11.4
2.1
%
2.5
3.3
—
5
13
(3019069) Monocytes/100 leukocytes in Blood
5
13
+∞
2.61
11.6
2.3
%
8.0
6.9
—
5
13
(3018010) Neutrophils/100 leukocytes in Blood
5
14
+∞
2.48
8.0
2.2
%
61.5
62.9
—
5
14
(3002030) Lymphocytes/100 leukocytes in Blood
5
15
+∞
2.35
11.4
2.2
%
22.6
26.0
—
5
15
(3013707) Erythrocyte sedimentation rate by Westergren method
5
23
+∞
1.29
9.8
3.1
mm/h
15.4
8.9
—
5
23
(3037467) Urinalysis macro (dipstick) panel - Urine
5
28
+∞
1.12
10.8
3.1
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
5
38
+∞
0.24
24.4
6.5
ml/min/173m2
97.5
87.3
—
5
29
(40761511) CBC panel - Blood by Automated count
5
43
+∞
0.00
38.0
9.5
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
5
42
+∞
0.00
32.8
10.0
umol/l
70.0
78.2
—
5
42
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3000492) Spirometry study
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_JUVEPOLYNOD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_JUVEPOLYNOD.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_JUVEPOLYNOD – Juvenile polyarteritis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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