Polyarteritis nodosa

M13_POLNODOSA

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M30.0
  • Hospital discharge: ICD-9 4460A
  • Hospital discharge: ICD-8 4460
  • Cause of death: ICD-10 M30.0
  • Cause of death: ICD-9 4460A
  • Cause of death: ICD-8 4460

2 out of 7 registries used, show all original rules.

249

4. Check minimum number of events

None

249

5. Include endpoints

None

249

6. Filter based on genotype QC (FinnGen only)

249

Control definitions (FinnGen only)

Control exclude
M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M30
Name in latin
Polyarteritis nodosa

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2412 1441 939
Only index persons 1633 982 651
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.03
Only index persons 0.03 0.04 0.02
Median age at first event (years)
Whole population 66.80 70.69 60.69
Only index persons 61.28 64.65 56.21

-FinnGen-

Key figures

All Female Male
Number of individuals 249 140 109
Unadjusted period prevalence (%) 0.05 0.05 0.05
Median age at first event (years) 59.70 59.01 60.59

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
217
Matched controls
2170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M30.0
ICD-10 Finland
Polyarteritis nodosa
+∞
220.0
172
*
L04AX01
ATC
azathioprine; systemic
25.0
38.7
55
29
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
36.5
34
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
9.5
35.3
81
128
L04AA06
ATC
mycophenolic acid; systemic
48.2
27.7
33
8
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
25.5
24
*
H02AB06
ATC
prednisolone; systemic
3.9
20.3
141
696
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
19.0
18
*
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
19.0
18
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.8
18.9
115
496
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
18.0
17
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
18.0
17
*
M05BA04
ATC
alendronic acid; oral
6.4
17.3
48
92
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
7.2
16.0
40
66
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
15.8
15
*
L01AA01
ATC
cyclophosphamide; systemic
48.8
15.3
18
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.6
14.8
56
152
4460A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa[POLYARTERITIS NODOSA (CLASSICA)]
+∞
14.7
14
*
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
45.9
14.3
17
*
C03CA01
ATC
furosemide; systemic
3.1
13.5
105
507
A11CC03
ATC
alfacalcidol; systemic
13.4
13.5
23
19
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.8
12.9
45
111
N085, M318
ICD-10 Finland
NA
+∞
12.6
12
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
11.5
12.6
23
22
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
5.0
12.1
40
93
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.4
12.1
37
79
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.6
12.0
31
53
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
20.3
11.8
17
9
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
11.6
11
*
F02.89*M30.0
ICD-10 Finland
Dementia in polyarteritis nodosa
+∞
11.6
11
*
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
+∞
11.6
11
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
16.2
11.5
18
12
Z94.0
ICD-10 Finland
Kidney transplant status
26.7
11.3
15
6
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.8
10.6
48
151
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
8.9
10.6
22
27
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
+∞
10.5
10
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
10.5
10
*
P01BA02
ATC
hydroxychloroquine; oral
5.0
10.2
33
75
L04AD01
ATC
ciclosporin; systemic
17.8
10.0
15
9
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
9.9
113
649
M30.3
ICD-10 Finland
Mucocutaneous lymph node syndrome [Kawasaki]
+∞
9.4
9
*
44600
ICD-8 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa
+∞
9.4
9
*
J01MA12
ATC
levofloxacin; systemic
3.0
9.3
62
258
TK800
NOMESCO Finland
Hemodialysis
9.7
9.2
18
20
127
Kela drug reimbursment
Transplant complication
16.5
9.2
14
9
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.1
9.1
36
100
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.9
9.1
22
35
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
8.9
76
368
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
8.4
8
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
8.4
8
*
TGC00
NOMESCO Finland
Bronchial lavation
10.6
8.2
15
15
H02AB07
ATC
prednisone; oral
3.2
8.1
45
164
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
23.0
8.1
11
5
A12AA04
ATC
calcium carbonate; oral
9.0
8.0
16
19
A02BC01
ATC
omeprazole; systemic
2.5
7.9
78
401
R50.9
ICD-10 Finland
Fever, unspecified
3.1
7.8
45
169
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
46.7
7.8
9
*
L04AA01
ATC
[U] ciclosporin; systemic
19.2
7.7
11
6
H02AB04
ATC
methylprednisolone; systemic
2.9
7.6
49
196
N03AX16
ATC
pregabalin; oral
2.5
7.6
65
312
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.6
7.4
25
60
I77.6
ICD-10 Finland
Arteritis, unspecified
+∞
7.3
7
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
7.3
7
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.1
7.3
28
76
N30.0
ICD-10 Finland
Acute cystitis
2.9
7.2
45
178
D69.0
ICD-10 Finland
Allergic purpura
31.1
7.2
9
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.9
7.2
29
83
C08CA01
ATC
amlodipine; oral
2.2
7.0
94
554
S97
ICPC
Chronic ulcer skin
4.9
7.0
22
49
A12BA01
ATC
potassium chloride; oral
4.3
7.0
25
64
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.7
7.0
19
36
J01FF01
ATC
clindamycin; systemic
2.4
6.8
70
363
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.9
6.8
21
46
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
41.4
6.8
8
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
6.7
48
206
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
6.7
75
408
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
12.8
6.7
11
9
N18.0
ICD-10 Finland
End-stage renal disease
10.5
6.6
12
12
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
6.4
68
360
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
6.4
46
198
ZX120
NOMESCO Finland
Intravenous
3.2
6.3
32
110
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
6.3
6
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
6.3
6
*
L52
ICD-10 Finland
Erythema nodosum
27.5
6.3
8
*
B03XA02
ATC
darbepoetin alfa; parenteral
8.1
6.2
13
17
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.6
6.1
26
78
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.1
6.1
18
38
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.0
6.0
23
63

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
48
41
14.26
48.66
4.0
1.1
iu/ml
9.1
—
—
8
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
34
30
12.97
33.40
3.1
1.1
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
75
202
4.88
26.81
1.8
1.2
titre
544.0
360.0
0.31
20
49
(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
24
29
9.05
18.70
7.9
7.4
iu/ml
471.8
178.4
—
8
5
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
29
48
6.71
17.27
2.7
1.4
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
49
133
4.34
16.83
7.8
3.3
ng/l
124.7
76.3
1.85
43
117
(3004588) Protein electrophoresis panel - Serum or Plasma
43
106
4.69
16.67
2.0
2.4
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
17
15
12.09
16.37
1.5
1.1
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
47
127
4.33
16.21
2.1
2.9
g/l
64.1
66.0
0.83
41
113
(42870588) Differential panel, method unspecified - Blood
119
583
2.99
16.07
11.7
5.5
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
145
793
2.98
15.97
15.5
5.5
%
0.6
0.6
0.11
140
734
(3023520) Reticulocytes [#/volume] in Blood
48
145
3.86
14.14
2.0
2.9
e9/l
76.7
73.9
0.14
36
114
(3001604) Monocytes [#/volume] in Blood
149
874
2.75
13.62
14.1
5.3
e9/l
0.6
0.6
0.97
143
759
(3006315) Basophils [#/volume] in Blood
149
877
2.74
13.47
14.3
5.3
e9/l
0.0
0.0
0.03
143
765
(3017143) Hepatitis C virus Ab [Presence] in Serum
53
179
3.49
13.19
2.1
1.5
—
—
—
0
0
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
22
36
6.61
13.17
1.5
1.2
u/ml
4.2
2.5
—
5
5
(3000850) Epithelial cells [#/volume] in Urine
91
424
2.81
12.97
5.1
2.5
e6/l
3.2
6.5
0.99
85
373
(3013115) Eosinophils [#/volume] in Blood
151
909
2.68
12.83
15.2
5.6
e9/l
0.2
0.2
0.55
146
794
(3027945) Reticulocytes/100 erythrocytes in Blood
58
212
3.26
12.70
4.6
2.5
%
2.0
1.9
0.21
53
192
(40760888) Immunoglobulin light chains.free panel - Serum
19
28
7.26
12.48
1.6
7.1
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
103
528
2.62
11.98
6.2
4.5
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
20
33
6.50
11.85
1.2
1.4
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
130
748
2.54
11.83
3.3
2.2
nmol/l
80.1
74.7
1.41
125
660
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
148
905
2.57
11.82
14.8
6.7
mmol/l
1.2
1.2
0.71
129
761
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
60
236
3.03
11.52
2.0
1.6
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
63
257
2.94
11.32
4.6
2.1
%
18.8
22.2
1.16
53
217
(3002179) Metamyelocytes/100 leukocytes in Blood
42
137
3.48
10.93
6.4
4.0
%
0.4
0.6
0.57
13
39
(21491868) Cryoglobulin [Mass/volume] in Serum
14
5
29.51
10.84
1.4
1.0
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
44
152
3.30
10.45
7.1
4.0
%
0.7
0.8
0.29
16
53
(3021440) Promyelocytes/100 leukocytes in Blood
42
142
3.35
10.32
7.2
4.1
%
0.0
0.1
1.49
16
48
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
118
686
2.37
10.04
6.1
2.9
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
47
5.04
9.98
4.0
2.0
u/ml
0.3
0.3
0.34
14
24
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
134
828
2.34
9.84
12.6
6.0
mmol/l
1.2
1.2
0.30
129
735
(46235355) HIV 1 and 2 tests - Meaningful Use set
65
292
2.66
9.60
2.2
1.8
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
22
49
4.83
9.51
1.9
1.4
iu/ml
0.2
0.0
—
5
9
(3011412) CD3 cells [#/volume] in Blood
14
20
7.36
9.38
1.9
2.0
e9/l
1.2
0.9
—
8
9
(3017817) Protein [Mass] in Urine collected for unspecified duration
13
17
8.01
9.36
1.9
3.5
—
—
—
0
0
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
27
73
4.03
9.16
1.3
2.2
u/l
36.4
38.8
0.27
22
64
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
17
31
5.81
9.10
1.2
1.2
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
105
608
2.26
8.73
6.2
3.1
e6/l
35.2
140.3
0.50
95
475
(4062490)
10
10
10.38
8.70
1.2
1.2
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
15
26
6.07
8.43
1.5
1.2
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
92
515
2.25
8.21
6.2
3.2
mg/l
97.3
174.0
0.27
71
336
(3000991) Gas panel - Venous blood
38
140
3.02
8.04
10.7
9.5
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
14
24
6.12
7.94
1.5
1.1
u/ml
2.8
2.3
—
5
10
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
33
114
3.18
7.78
5.6
3.0
mmol/l
1.4
1.4
0.01
27
85
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
11
15
7.63
7.61
1.0
1.0
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
15
29
5.44
7.55
1.5
1.3
—
—
—
0
0
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
27
84
3.48
7.50
10.4
3.9
mmol/l
23.8
23.8
0.02
27
77
(3020682) Albumin/Creatinine [Ratio] in Urine
94
551
2.13
7.33
6.8
4.1
mg/mmol
24.2
8.9
1.15
69
345
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
15
30
5.26
7.28
4.7
2.9
%
60.5
59.3
0.10
15
30
(3009508) Creatinine [Moles/volume] in Urine
93
544
2.13
7.28
6.3
3.1
mmol/l
6.8
7.5
0.88
80
448
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
37
142
2.89
7.27
1.5
1.5
—
—
—
0
0
(3009343) pH of Capillary blood
33
119
3.04
7.23
5.7
3.0
ph
7.4
7.4
—
5
16
(3012544) pH of Venous blood
41
167
2.74
7.22
8.6
3.7
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
34
125
2.99
7.21
1.4
1.4
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
14
27
5.43
7.05
4.0
2.3
e9/l
4.4
4.7
0.13
14
27
(40768443) Skin Pathology biopsy report
27
88
3.32
6.98
1.3
1.3
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
84
479
2.14
6.97
3.2
2.0
mg/l
3.2
3.2
0.06
78
411
(3019309) Folate [Moles/volume] in Red Blood Cells
71
379
2.22
6.95
1.8
1.7
nmol/l
1247.8
1183.4
0.22
61
286
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
62
313
2.31
6.94
2.3
1.8
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
11
17
6.72
6.83
1.1
1.2
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
10
14
7.40
6.75
1.3
1.5
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
10
14
7.40
6.75
1.2
1.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
109
693
2.02
6.70
7.5
3.5
e6/l
49.8
77.5
0.59
96
507
(3018418) pH of Serum or Plasma
93
559
2.06
6.67
9.9
3.6
ph
7.4
7.4
0.15
20
98
(3026782) Osmolality of Urine
72
393
2.17
6.64
4.2
2.8
mosm/kgh2o
555.7
545.7
0.15
65
334
(3007853) Bacteria identified in Skin by Aerobe culture
47
216
2.45
6.46
2.6
1.6
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
12
22
5.68
6.35
5.8
3.1
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
65
347
2.18
6.31
2.0
1.4
g/l
2.6
2.5
0.10
48
204
(3026493) Urate [Moles/volume] in Serum or Plasma
82
479
2.06
6.29
3.3
2.6
umol/l
1991.7
7853.3
1.21
71
407
(3021447) Carbon dioxide [Partial pressure] in Venous blood
39
166
2.60
6.28
9.1
3.6
kpa
5.9
5.6
1.45
39
161
(3048929) Epstein Barr virus Ab [Presence] in Serum
17
43
4.17
6.28
1.6
1.2
—
—
—
0
0
(3037121) Protein [Mass/volume] in Urine
21
63
3.55
6.15
3.6
2.9
g/l
0.6
0.2
1.17
12
21
(3025159) Blasts/100 leukocytes in Blood
34
138
2.70
6.01
8.0
4.1
%
0.0
0.2
0.57
14
44
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
10
17
6.09
5.67
2.6
2.7
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
55
286
2.18
5.65
2.9
1.9
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
20
63
3.36
5.45
2.5
2.6
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
85
528
1.93
5.35
5.5
2.8
—
—
—
0
0
(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
5
0
+∞
5.22
3.2
0.0
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
15
40
3.93
5.17
8.8
2.7
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
55
296
2.10
5.15
1.5
1.2
iu/ml
32.8
27.6
0.14
19
98
(3030467) Casts [#/volume] in Urine by Automated count
86
542
1.90
5.15
5.7
3.0
e6/l
0.4
0.5
0.29
72
409
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
53
282
2.12
5.11
1.4
1.2
u/ml
19.8
12.1
0.26
25
107
(3022313) Gas panel - Capillary blood
23
83
2.95
5.03
6.1
3.0
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
15
41
3.83
5.00
1.3
1.4
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
16
47
3.57
4.83
1.1
1.2
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
10
20
5.17
4.82
1.6
1.2
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
8
7
11.75
4.82
1.1
1.0
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
25
97
2.75
4.81
1.2
1.3
—
43.6
—
0
6
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
66
395
1.91
4.56
2.0
1.8
mg/l
1.0
1.5
1.77
57
318
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
18
60
3.16
4.50
3.4
2.3
g/l
3.2
3.8
1.01
13
43
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
18
60
3.16
4.50
3.4
2.3
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
19
66
3.03
4.44
1.7
1.7
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
97
660
1.77
4.41
4.1
3.2
mmol/l
2.3
2.4
2.30
86
571
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
20
72
2.93
4.40
1.9
1.8
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
111
789
1.73
4.31
12.1
8.0
inr
1.2
1.2
0.64
36
247
(3017704) Immunofixation for Urine
7
6
11.95
4.30
1.1
1.0
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
163
1291
1.76
4.27
10.9
4.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
42
222
2.07
4.09
1.8
1.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
31
145
2.30
4.07
1.7
1.7
—
—
—
0
0
(4268621)
9
14
6.62
4.02
2.6
1.9
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
9
14
6.62
4.02
1.1
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
9
14
6.62
4.02
1.1
1.2
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
9
14
6.62
4.02
1.1
1.2
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
59
354
1.87
4.00
4.5
3.7
ng/l
888.6
181.2
0.76
49
289
(3019225) pH of Specimen
35
174
2.18
3.98
9.4
4.1
—
—
—
0
0
(3038026) Centromere Ab [Units/volume] in Serum
8
11
7.47
3.89
1.1
1.2
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
9
15
6.18
3.85
1.1
1.2
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
9
15
6.18
3.85
2.3
1.6
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
9
15
6.18
3.85
1.1
1.2
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
9
15
6.18
3.85
1.1
1.2
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
89
610
1.71
3.85
4.3
3.2
u/l
34.7
33.0
0.10
84
576
(3021788) Differential panel - Synovial fluid
11
29
3.92
3.84
2.2
1.5
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
7
8
8.96
3.79
1.3
1.0
iu/ml
79.1
122.5
—
7
8
(40760892) CBC W Ordered Manual Differential panel - Blood
64
401
1.80
3.77
11.2
4.5
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
16
57
2.93
3.59
1.4
1.1
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
144
1133
1.64
3.58
8.2
5.0
mmol/l
7.0
6.8
0.52
138
1045
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
84
578
1.68
3.53
3.1
2.5
u/l
49.5
55.3
1.09
78
539
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
8
13
6.32
3.53
2.4
2.3
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
38
206
2.00
3.45
2.7
2.1
ug/g
162.9
146.3
0.14
32
169
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
39
215
1.97
3.38
2.5
1.7
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
8
14
5.86
3.37
1.3
3.9
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
14
48
3.03
3.36
1.5
1.5
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
14
48
3.03
3.36
1.5
1.5
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
39
219
1.93
3.21
2.5
1.8
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
7
11
6.51
3.20
1.1
1.2
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
10
29
3.55
3.08
1.7
1.3
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
8
16
5.13
3.07
1.9
1.4
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
13
45
2.99
3.07
2.0
1.3
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
121
936
1.57
3.07
6.0
3.7
estimate
0.0
0.0
0.00
28
178
(3044640) Blood type and Crossmatch panel - Blood
83
588
1.62
3.05
3.8
2.4
—
—
—
0
0
(1616796) Gas panel - Central venous blood
12
40
3.10
3.01
2.8
2.5
—
—
—
0
0
(3015736) pH of Urine
96
707
1.58
2.99
6.1
3.6
—
—
—
0
0
(3020073) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Specimen
5
5
10.17
2.99
2.2
2.4
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
42
663
0.56
2.99
3.3
3.0
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
22
102
2.27
2.97
5.9
6.1
mmol/l
24.3
24.2
0.06
22
102
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
20
89
2.36
2.95
9.8
15.5
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
119
924
1.55
2.92
8.3
5.0
estimate
0.0
0.0
0.00
30
185
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
7
13
5.50
2.89
3.4
2.7
%
83.9
96.2
—
7
13
(3035947) Staphylolysin Ab [Units/volume] in Serum
6
9
6.80
2.88
1.5
1.1
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
73
508
1.62
2.86
6.2
3.9
estimate
0.0
0.0
0.00
29
176
(3021589) Normoblasts [#/volume] in Blood
107
815
1.55
2.85
18.0
9.9
e9/l
0.0
0.0
0.63
102
676
(3031040) Bacteria [#/volume] in Urine by Automated count
154
1271
1.55
2.84
8.0
4.5
e6/l
11196.1
2273.5
—
9
31
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
112
863
1.54
2.82
5.7
4.2
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
118
921
1.53
2.80
6.1
3.7
estimate
0.0
0.0
0.00
28
187
(3002256) Pathology report gross observation
40
237
1.82
2.80
1.4
1.2
—
—
—
0
0
(3045683) HLA typing for celiac disease panel - Blood or Tissue
5
6
8.47
2.76
1.0
1.0
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
11
37
3.06
2.73
2.7
3.1
kpa
9.0
8.5
0.41
11
37
(3013290) Carbon dioxide [Partial pressure] in Blood
11
37
3.06
2.73
2.7
3.1
kpa
4.9
5.0
0.44
11
37
(3000093) Morphology [Interpretation] in Blood Narrative
8
19
4.31
2.70
1.1
1.2
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
14
55
2.64
2.66
1.5
1.2
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
102
780
1.52
2.62
2.4
2.0
pmol/l
91.4
93.8
0.24
67
400
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
11
38
2.98
2.61
1.5
1.6
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
7
15
4.77
2.61
1.4
1.9
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
7
15
4.77
2.61
1.4
1.9
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
7
15
4.77
2.61
1.4
1.9
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
7
15
4.77
2.61
1.0
1.1
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
5
7
7.26
2.56
1.4
1.6
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
6
11
5.56
2.56
1.2
1.5
—
—
—
0
0
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
6
11
5.56
2.56
1.2
1.5
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
158
0.30
2.52
1.6
1.7
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
26
138
1.99
2.52
6.7
2.7
ml/min/173m2
59.6
61.3
0.06
13
61
(3021960) Folate [Moles/volume] in Serum or Plasma
68
479
1.58
2.50
1.9
1.5
nmol/l
17.9
20.5
1.06
61
406
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
7
16
4.47
2.49
1.0
1.1
—
—
—
0
0
(40758558) Short blood count panel - Blood
66
464
1.57
2.45
11.2
6.8
—
—
—
0
0
(44790047)
8
22
3.72
2.38
1.8
1.3
—
—
—
0
0
(44790049)
8
22
3.72
2.38
1.8
1.3
—
—
—
0
0
(44806118)
8
22
3.72
2.38
1.8
1.3
—
—
—
0
0
(44790048)
8
22
3.72
2.38
1.8
1.3
—
—
—
0
0
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
5
8
6.35
2.38
1.6
1.0
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
61
424
1.58
2.37
3.7
2.4
—
—
—
0
0
(40761535) Cells panel - Urine sediment
27
149
1.91
2.35
5.4
3.3
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
14
59
2.45
2.34
2.0
1.4
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
14
59
2.45
2.34
3.1
4.0
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
80
593
1.51
2.33
4.0
3.1
ng/l
3470.0
1498.1
0.54
72
505
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
28
3.30
2.33
1.2
1.2
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
7
18
3.97
2.27
3.3
2.3
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
7
18
3.97
2.27
1.0
1.9
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
9
29
3.18
2.25
2.6
3.9
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
34
206
1.75
2.22
3.5
3.4
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
7
19
3.76
2.16
1.1
1.2
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
7
20
3.57
2.07
1.0
1.8
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
10
38
2.70
2.03
1.7
1.4
—
—
—
0
0
(4035726)
28
165
1.79
2.01
1.2
1.4
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
45
2.51
1.96
1.2
1.2
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
8
27
3.03
1.95
1.4
1.4
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
10
39
2.63
1.94
3.0
2.2
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
9
34
2.71
1.88
1.6
1.4
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
9
34
2.71
1.88
1.3
1.5
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
93
736
1.42
1.88
2.5
2.1
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
9
35
2.63
1.82
1.4
1.3
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
7
23
3.10
1.81
1.4
1.5
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
45
311
1.55
1.78
4.6
2.7
e6/l
1.4
2.4
0.69
26
170
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
6
18
3.39
1.75
1.7
1.3
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
5
13
3.90
1.72
1.4
1.2
—
—
—
0
0
(4306422)
6
19
3.21
1.67
1.0
1.1
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
6
19
3.21
1.67
1.0
1.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
46
326
1.50
1.63
4.5
2.6
e6/l
1.0
1.0
0.01
27
183
(3019060) Gas panel - Arterial blood
22
129
1.77
1.63
8.5
7.1
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
7
26
2.74
1.59
3.0
2.7
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
7
26
2.74
1.59
1.1
1.1
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
6
20
3.05
1.59
1.0
1.2
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
19
108
1.82
1.55
1.8
1.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
76
598
1.39
1.55
4.2
3.2
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
54
400
1.45
1.54
1.2
1.2
u/ml
0.8
1.1
0.54
12
101
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
5
15
3.38
1.53
1.2
1.3
—
—
—
0
0
(3022145) Colonoscopy Study observation
31
204
1.59
1.52
1.5
1.3
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
9
37
2.48
1.49
1.6
1.2
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
9
37
2.48
1.49
1.6
1.2
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
9
40
2.30
1.41
1.1
1.5
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
94
777
1.34
1.39
6.9
3.9
ng/l
41.9
46.8
0.17
69
547
(40768806) Pleura Pathology biopsy report
6
23
2.65
1.37
1.7
1.6
—
—
—
0
0
(3011648) Oxygen content in Venous blood
5
17
2.98
1.36
4.6
1.8
%
11.1
11.4
—
5
17
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
9
43
2.13
1.31
1.0
1.1
—
—
—
0
0
(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method
6
24
2.54
1.31
3.0
2.2
—
35.7
—
0
6
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
10
48
2.13
1.29
1.7
1.3
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
29
196
1.54
1.29
3.8
4.4
ug/l
14.8
62.1
0.60
21
166
(3012441) Differential panel - Pleural fluid
5
19
2.66
1.22
1.4
1.3
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
5
19
2.66
1.22
1.0
1.4
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
14
79
1.82
1.19
1.7
1.8
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
35
251
1.46
1.19
1.3
1.2
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
200
1867
1.36
1.13
35.9
14.4
mg/l
24.5
23.6
0.17
181
1474
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
7
30
2.37
1.13
1.4
1.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
9
163
0.54
1.13
1.9
2.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
52
405
1.36
1.12
6.3
3.7
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
31
2.29
1.11
1.9
1.5
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
5
21
2.41
1.09
8.6
3.8
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
22
2.30
1.04
1.0
1.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
24
166
1.49
0.99
4.6
3.6
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
5
23
2.20
0.98
1.0
1.5
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
5
23
2.20
0.98
1.0
1.2
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
5
23
2.20
0.98
1.0
1.5
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
5
23
2.20
0.98
1.0
1.5
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
5
23
2.20
0.98
1.0
1.5
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
5
23
2.20
0.98
1.0
1.5
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
25
177
1.46
0.93
6.5
2.3
ug/l
7.6
5.4
0.35
20
158
(3000330) Specific gravity of Urine by Test strip
5
101
0.48
0.91
4.6
4.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
37
283
1.36
0.90
1.6
1.4
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
17
111
1.57
0.90
1.8
1.6
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
168
1797
0.80
0.87
4.8
4.5
mmol/l
5.9
6.0
0.36
154
1612
(21494755) Public health laboratory ask at order entry panel
8
140
0.56
0.86
1.1
1.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
11
176
0.61
0.83
1.8
2.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
85
735
1.24
0.83
6.5
3.9
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
6
33
1.84
0.79
8.8
2.5
—
—
—
0
0
(3034274) Bile acid [Moles/volume] in Serum --fasting
0
25
0.00
0.79
0.0
3.0
—
5.8
—
0
17
(3041096) Erythrocytes [Presence] in Urine by Automated
65
548
1.25
0.79
5.7
3.3
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
18
124
1.49
0.77
7.9
2.7
e9/l
4.8
4.1
0.68
12
92
(3049717) Cytology report of Urine Cyto stain
11
67
1.67
0.76
2.6
2.7
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
5
24
2.10
0.75
1.4
1.3
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
5
24
2.10
0.75
1.0
1.5
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
5
25
2.02
0.73
1.0
1.1
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
57
478
1.25
0.73
1.7
1.7
mmol/l
1.7
1.4
1.22
51
400
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
9
145
0.61
0.72
1.1
1.4
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
28
360
0.75
0.71
2.4
3.0
ug/l
0.6
0.8
0.99
17
234
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
5
27
1.87
0.69
1.0
1.1
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
29
225
1.33
0.67
3.9
4.5
%
35.7
31.2
1.08
21
133
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
10
62
1.64
0.66
1.1
1.0
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
14
95
1.50
0.65
1.2
1.3
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
5
30
1.68
0.61
1.4
1.0
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
21
0.00
0.60
0.0
2.8
—
90.4
—
0
21
(3019150) Specific gravity of Urine by Refractometry
48
405
1.23
0.59
8.2
4.1
kg/l
1.0
1.0
—
7
57
(4010399)
20
150
1.36
0.58
1.4
1.4
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
18
133
1.38
0.57
1.3
1.1
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
48
410
1.21
0.53
1.8
1.7
pmol/l
465.1
438.3
0.26
42
344
(40761511) CBC panel - Blood by Automated count
188
1954
0.85
0.50
31.0
13.8
—
—
—
0
0
(3003338) MCHC [Mass/volume]
146
1541
0.87
0.46
46.0
18.8
g/l
329.5
332.1
2.51
146
1533
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
129
1208
1.14
0.45
3.8
3.0
u/l
65.4
49.5
1.13
123
1133
(3000492) Spirometry study
20
157
1.30
0.45
1.7
1.5
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
1.5
—
1.0
—
0
15
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay
0
18
0.00
0.40
0.0
1.0
—
39.4
—
0
10
(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid
0
18
0.00
0.40
0.0
1.0
—
288.1
—
0
10
(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid
0
18
0.00
0.40
0.0
1.0
—
512.1
—
0
10
(4281824)
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
28
235
1.22
0.38
10.3
7.3
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
5
76
0.65
0.36
1.4
1.5
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
29
247
1.20
0.35
20.6
25.3
inr
1.4
1.3
—
8
30
(3013512) EKG study
62
564
1.13
0.33
5.4
4.1
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
7
99
0.70
0.31
1.3
2.9
pmol/l
4.5
4.3
—
7
86
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
7
53
1.33
0.31
2.0
1.4
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
45
497
0.88
0.28
4.4
4.4
%
23.0
22.0
0.13
21
236
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
8
65
1.24
0.27
1.6
1.6
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
14
113
1.25
0.27
1.1
1.2
iu/ml
43.3
151.1
—
6
42
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
16
192
0.82
0.26
1.3
1.8
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
6
84
0.71
0.24
1.8
1.9
—
—
—
0
0
(3044889) 12 lead EKG panel
127
1321
0.92
0.24
4.3
3.9
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
176
1805
0.91
0.23
5.0
4.4
mmol/l
1.4
1.4
1.25
161
1646
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
182
1863
0.91
0.22
5.3
5.0
mmol/l
2.5
2.7
2.04
168
1697
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3003171) Aldosterone [Moles/volume] in Serum or Plasma --upright
0
10
0.00
0.21
0.0
1.2
—
367.6
—
0
5
(3015183) Erythrocyte sedimentation rate
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(4211845)
0
10
0.00
0.21
0.0
4.6
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
107
1116
0.93
0.21
3.5
3.0
—
—
—
0
0
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
6
49
1.23
0.20
1.0
1.1
—
4.1
—
0
6
(3013139) Helicobacter pylori Ag [Presence] in Stool
12
99
1.22
0.20
1.3
1.2
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
9
82
1.10
0.15
1.0
1.0
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
163
1664
0.94
0.15
33.7
15.8
%
38.0
39.7
1.31
100
1181
(3001019) Free T4 and TSH panel - Serum or Plasma
9
83
1.09
0.15
2.2
1.8
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
178
1812
0.94
0.14
4.9
4.5
mmol/l
4.4
4.6
1.92
165
1666
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
172
1752
0.94
0.14
4.5
4.0
mmol/l
1.4
1.3
0.54
158
1586
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
176
1734
1.05
0.10
7.5
5.9
mmol/mol
41.1
40.3
0.49
165
1599
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
5
44
1.14
0.10
1.2
1.5
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
51
489
1.05
0.09
1.7
1.5
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
6
57
1.05
0.08
1.0
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
6
57
1.05
0.08
1.0
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
6
58
1.04
0.08
1.0
1.2
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
5
64
0.78
0.08
1.4
1.8
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
26
244
1.07
0.08
1.5
1.5
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
8
92
0.87
0.07
1.0
1.3
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
12
131
0.91
0.05
2.8
2.3
nmol/l
11.4
14.1
0.67
12
124
(3022621) pH of Urine by Test strip
12
128
0.93
0.02
2.8
3.1
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
60
609
0.98
0.02
4.1
4.9
ug/l
2.0
2.3
0.34
55
544
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
176
1759
1.00
0.00
29.8
13.7
ml/min/173m2
74.5
79.0
1.41
153
1431
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
169
1693
0.99
0.00
4.6
4.7
mu/l
2.1
1.9
1.33
158
1510
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
140
1395
1.01
0.00
3.9
3.9
pmol/l
15.2
14.8
0.94
123
1238
(3020891) Body temperature
7
70
1.00
0.00
8.3
3.8
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(44806420)
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3035509) Tobramycin [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.0
—
1.1
—
0
6
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037826) lamoTRIgine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
18.3
—
0
5
(3051593) INR in Capillary blood by Coagulation assay
0
9
0.00
0.00
0.0
18.7
—
—
—
0
0
(3044007) Cell count panel - Peritoneal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
5
59
0.84
0.00
2.6
1.5
—
—
—
0
0
(3011436) Histone Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(42868417) European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(3012494) Peanut IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
0.6
—
0
5
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3025443) Phadiatop IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4034850)
5
59
0.84
0.00
17.0
11.4
—
—
—
0
0
(3027231) Wheat IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood
0
5
0.00
0.00
0.0
2.2
—
1.2
—
0
5
(3021162) Amylase [Enzymatic activity/volume] in Specimen
0
5
0.00
0.00
0.0
2.6
—
10952.0
—
0
5
(3022689) Creatine [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
9
0.00
0.00
0.0
5.0
—
—
—
0
0
(40758355) Pancreatic polypeptide [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
4.2
—
61.7
—
0
6
(42868499) Enterovirus IgG Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006653) Thiamine [Moles/volume] in Blood
0
7
0.00
0.00
0.0
1.1
—
146.7
—
0
7
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
9
93
0.97
0.00
2.3
2.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_POLNODOSA and mortality.

Females

Parameter HR [95% CI] p-value
M13_POLNODOSA 2.456 [2.03, 2.97] < 0.001
Birth year 1.0 [0.99, 1.01] 0.939

During the follow-up period (1.1.1998 — 31.12.2019), 585 out of 1085 females with M13_POLNODOSA died.

Males

Parameter HR [95% CI] p-value
M13_POLNODOSA 2.422 [1.81, 3.24] < 0.001
Birth year 0.99 [0.98, 1.0] 0.042

During the follow-up period (1.1.1998 — 31.12.2019), 269 out of 625 males with M13_POLNODOSA died.

Mortality risk

Mortality risk for people of age

years, who have M13_POLNODOSA.

N-year risk Females Males
1 0.36% 0.392%
5 1.66% 3.074%
10 4.388% 7.997%
15 8.081% 15.044%
20 13.718% 24.31%

Relationships between endpoints

Index endpoint: M13_POLNODOSA – Polyarteritis nodosa

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data