Polyarteritis with lung involvement [Churg-Strauss]/EGPA

M13_CHURGSTRAUSS

Churg-Strauss syndrome: Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome, is a systemic vasculitis of small-to medium vessels, characterized by asthma, transient pulmonary infiltrates, and hypereosinophilia.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M30.1
  • Hospital discharge: ICD-9 4460B
  • Cause of death: ICD-10 M30.1
  • Cause of death: ICD-9 4460B

2 out of 7 registries used, show all original rules.

140

4. Check minimum number of events

None

140

5. Include endpoints

None

140

6. Filter based on genotype QC (FinnGen only)

140

Control definitions (FinnGen only)

Control exclude
M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M30
Name in latin
Polyarteritis nodosa cum manifestationibus pulmonalibus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 674 428 243
Only index persons 564 368 196
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 59.17 58.51 60.28
Only index persons 57.40 56.70 58.70

-FinnGen-

Key figures

All Female Male
Number of individuals 140 93 47
Unadjusted period prevalence (%) 0.03 0.03 0.02
Median age at first event (years) 53.71 52.24 56.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
124
Matched controls
1239
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
+∞
175.9
123
*
H02AB06
ATC
prednisolone; systemic
28.3
40.1
116
420
D72.1
ICD-10 Finland
Eosinophilia
467.5
35.9
34
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
11.8
33.2
77
151
L04AX01
ATC
azathioprine; systemic
33.3
31.4
41
18
J45.9
ICD-10 Finland
Asthma, unspecified
10.0
28.7
71
146
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
13.2
28.1
54
68
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
18.1
26.2
42
34
J45.1
ICD-10 Finland
Nonallergic asthma
15.6
25.6
44
42
R03DC03
ATC
montelukast; oral
9.3
25.4
63
124
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.9
25.1
85
268
R03AC02
ATC
salbutamol; inhalant
6.7
19.2
100
476
J45.0
ICD-10 Finland
Predominantly allergic asthma
9.7
18.4
40
58
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
12.1
17.6
33
36
R03AK06
ATC
salmeterol and fluticasone; inhalant
7.1
17.3
48
101
J32.4
ICD-10 Finland
Chronic pansinusitis
33.0
17.2
22
8
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
18.3
15.7
24
16
R01AD08
ATC
fluticasone; nasal
5.0
15.6
68
242
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
9.2
15.5
34
49
R03AK08
ATC
formoterol and beclometasone; inhalant
15.3
15.2
25
20
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
8.4
15.2
35
55
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
18.5
15.1
23
15
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.7
15.0
83
372
R03AC12
ATC
salmeterol; inhalant
12.5
14.9
27
27
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
+∞
14.9
14
*
M05BA04
ATC
alendronic acid; oral
8.8
14.4
32
47
J01MA14
ATC
moxifloxacin; systemic
8.4
14.0
32
49
R03AK07
ATC
formoterol and budesonide; inhalant
5.2
13.6
50
143
UDH02
NOMESCO Finland
Rhinopharyngoscopy
8.4
13.6
31
47
UGC12
NOMESCO Finland
Flexible bronchoscopy
9.2
13.1
28
38
R03BA02
ATC
budesonide; inhalant
5.2
12.8
46
127
R50.9
ICD-10 Finland
Fever, unspecified
6.0
12.7
38
85
J33.0
ICD-10 Finland
Polyp of nasal cavity
13.1
12.6
22
20
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
11.0
12.1
23
25
XG474
NOMESCO Finland
Exhalation nntrogen oxide
13.0
12.1
21
19
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
33.8
12.0
15
5
R03BB04
ATC
tiotropium bromide; inhalant
6.9
11.9
31
57
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
11.6
11
*
J45.8
ICD-10 Finland
Mixed asthma
13.0
11.5
20
18
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
4.7
11.5
45
135
R03BA05
ATC
fluticasone; inhalant
4.5
11.2
45
138
TDM10
NOMESCO Finland
Puncture of maxillary antrum
10.0
11.1
22
26
N02AX02
ATC
tramadol; systemic, rectal
3.7
11.1
74
351
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.3
10.8
46
148
R03BA08
ATC
ciclesonide; inhalant
6.4
10.7
29
56
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
10.6
10
*
J33.8
ICD-10 Finland
Other polyp of sinus
14.9
10.5
17
13
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
9.5
10.3
21
26
H02AB07
ATC
prednisone; oral
4.6
10.3
40
117
WZC30
NOMESCO Finland
Teaching
5.2
10.3
34
84
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.2
10.2
25
42
DHB20
NOMESCO Finland
Polypectomy of internal nose
22.3
10.1
14
7
D69.0
ICD-10 Finland
Allergic purpura
107.9
9.6
10
*
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
+∞
9.5
9
*
M30.0
ICD-10 Finland
Polyarteritis nodosa
+∞
9.5
9
*
R03BA01
ATC
beclometasone; inhalant
4.6
9.5
35
97
TGC00
NOMESCO Finland
Bronchial lavation
14.0
9.1
15
12
UDM02
NOMESCO Finland
Sinoscopy
14.0
9.1
15
12
H02AB04
ATC
methylprednisolone; systemic
4.2
8.8
37
115
R03DA04
ATC
theophylline; systemic, rectal
7.7
8.8
20
30
L04AA06
ATC
mycophenolic acid; systemic
21.9
8.7
12
6
J45
ICD-10 Finland
Asthma
5.1
8.6
28
67
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
96.3
8.5
9
*
R01AD01
ATC
beclometasone; nasal
4.2
8.4
34
102
A02BC02
ATC
pantoprazole; systemic
3.4
8.3
97
637
R03AC13
ATC
formoterol; inhalant
7.0
8.3
20
33
L01AA01
ATC
cyclophosphamide; systemic
35.9
8.2
10
*
DHA10
NOMESCO Finland
Biopsy of cavity of nose
23.9
8.2
11
5
ZX120
NOMESCO Finland
Intravenous
4.5
8.2
30
82
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
10.5
8.0
15
16
J01MA12
ATC
levofloxacin; systemic
3.8
8.0
37
125
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.6
7.9
20
35
XG410
NOMESCO Finland
Flow-volume spirometry
7.6
7.9
18
27
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
13.0
7.8
13
11
Z01.8
ICD-10 Finland
Other specified special examinations
3.3
7.8
45
181
DPA30
NOMESCO Finland
Sphenotomy
26.9
7.7
10
*
J01FA06
ATC
roxithromycin; oral
2.9
7.6
68
365
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
7.4
7
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
7.4
7
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
7.4
7
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.9
7.3
20
39
R01AD09
ATC
mometasone; nasal
2.8
7.3
71
397
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.5
7.3
26
69
KCV04
NOMESCO Finland
Distension of bladder with fluid
21.6
7.3
10
5
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
32.1
7.3
9
*
A01AB09
ATC
miconazole; local oral
5.2
7.2
22
49
A02BC01
ATC
omeprazole; systemic
3.0
7.2
50
227
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.3
7.0
41
163
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.6
7.0
24
61
R03AK11
ATC
formoterol and fluticasone; inhalant
11.9
7.0
12
11
297
Kela drug reimbursment
NA
42.4
6.8
8
*
R03DX09
ATC
mepolizumab; parenteral
42.4
6.8
8
*
3028
Kela drug reimbursment
Mepolizumab
42.4
6.8
8
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.6
6.7
19
39
J46
ICD-10 Finland
Status asthmaticus
10.9
6.7
12
12
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
8.2
6.6
14
19
J01FF01
ATC
clindamycin; systemic
3.0
6.5
46
206
R03DC01
ATC
zafirlukast; oral
11.9
6.4
11
10
B01AA03
ATC
warfarin; systemic
3.4
6.4
32
114
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
19.2
6.4
9
5
P01BA02
ATC
hydroxychloroquine; oral
5.5
6.4
18
37
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.7
6.4
78
483
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
+∞
6.3
6
*
I77.6
ICD-10 Finland
Arteritis, unspecified
+∞
6.3
6
*
R06AX22
ATC
ebastine; oral
3.3
6.1
33
123
R03AC03
ATC
terbutaline; inhalant
3.7
6.1
27
87
ZXA10
NOMESCO Finland
Bilateral
3.2
6.1
34
131

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
40
15
36.93
60.28
3.5
1.1
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
39
24
22.14
47.97
5.4
1.1
iu/ml
12.2
—
—
7
0
(3021440) Promyelocytes/100 leukocytes in Blood
52
84
9.26
33.65
8.5
3.0
%
0.0
0.3
1.50
18
24
(3002179) Metamyelocytes/100 leukocytes in Blood
50
82
8.93
31.79
7.8
2.9
%
0.1
0.5
1.37
17
17
(3017181) Myelocytes/100 leukocytes in Blood
52
92
8.40
30.86
8.5
2.9
%
0.4
0.9
1.05
18
27
(3025159) Blasts/100 leukocytes in Blood
49
82
8.65
30.52
8.8
2.9
%
0.0
0.0
0.00
17
20
(3037522) Nuclear Ab [Titer] in Serum
62
135
7.45
30.23
1.5
1.3
titre
350.0
514.7
—
8
30
(3001604) Monocytes [#/volume] in Blood
122
560
10.17
25.61
19.0
5.5
e9/l
0.6
0.6
4.58
117
486
(3006315) Basophils [#/volume] in Blood
122
561
10.14
25.53
19.1
5.5
e9/l
0.0
0.0
2.25
117
489
(3013115) Eosinophils [#/volume] in Blood
124
582
10.89
25.31
21.0
5.8
e9/l
0.3
0.2
4.65
119
516
(42870588) Differential panel, method unspecified - Blood
96
359
6.33
25.15
17.8
5.1
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
122
569
9.90
24.87
19.3
5.5
e9/l
1.8
1.9
0.07
117
504
(4062490)
17
10
19.21
20.62
2.1
1.3
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
19
20
10.83
16.49
5.8
2.8
e9/l
5.1
5.6
0.22
19
20
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
19
21
10.31
15.92
6.4
2.8
%
60.6
61.0
0.03
19
21
(3023368) Bacteria identified in Blood by Culture
69
275
3.98
14.63
5.1
4.0
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
66
261
3.89
14.05
14.9
4.9
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
100
535
4.04
13.27
9.2
6.5
mmol/l
1.2
1.2
0.16
81
457
(1616796) Gas panel - Central venous blood
16
18
9.91
13.15
4.4
2.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
29
64
5.45
13.06
2.2
2.6
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
20
34
6.70
11.69
4.1
1.3
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
94
513
3.53
11.44
20.6
8.8
e9/l
0.0
0.0
0.50
87
411
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
25
55
5.32
11.23
4.7
3.1
mmol/l
2.0
1.7
0.18
19
45
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
15
7
23.77
10.94
1.3
1.0
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
13
14
10.13
10.93
1.5
2.2
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
14
17
9.04
10.81
1.5
2.0
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
91
498
3.36
10.80
7.3
5.4
mmol/l
1.2
1.2
0.28
85
455
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
18
31
6.52
10.35
3.2
2.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
117
767
4.20
10.03
10.2
3.9
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
12
13
10.00
10.02
3.0
1.6
—
—
—
0
0
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
23
52
5.10
9.97
1.2
3.3
u/l
30.9
42.1
1.67
23
47
(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
15
22
7.52
9.94
7.6
8.0
iu/ml
—
139.8
—
0
5
(3015235) Bicarbonate [Moles/volume] in Capillary blood
15
22
7.52
9.94
2.5
2.0
mmol/l
24.0
25.2
0.39
15
17
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
25
61
4.77
9.92
4.8
3.0
kpa
5.0
5.1
0.14
25
56
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
12
14
9.28
9.49
1.6
1.9
—
—
—
0
0
(3018418) pH of Serum or Plasma
68
335
3.00
9.31
5.9
3.7
ph
7.4
7.4
0.23
21
56
(3009261) Glucose [Presence] in Urine by Test strip
95
563
3.14
9.29
7.1
3.4
estimate
0.0
0.0
0.00
37
92
(3035350) Ketones [Presence] in Urine by Test strip
93
549
3.07
9.08
7.2
3.3
estimate
0.0
0.0
0.00
34
98
(3021601) Nitrite [Presence] in Urine by Test strip
94
559
3.07
9.04
8.9
4.6
estimate
0.0
0.0
0.00
38
94
(3003327) Ova and parasites identified in Stool by Light microscopy
20
44
5.14
8.91
2.0
1.5
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
10
10
10.69
8.74
1.1
1.1
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
12
16
8.11
8.55
1.6
1.9
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
43
171
3.19
8.45
2.6
1.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
53
242
2.92
8.14
2.3
1.3
g/l
2.3
2.6
0.68
45
141
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
14
24
6.37
8.02
3.3
1.9
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
35
128
3.31
7.85
2.5
1.5
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
10
12
8.90
7.67
3.5
3.0
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
54
256
2.81
7.66
1.8
1.6
mg/l
1.3
0.9
0.48
44
204
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
13
22
6.41
7.52
1.3
1.3
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
83
492
2.69
7.52
6.1
4.0
g/l
33.7
36.2
3.30
76
463
(3009508) Creatinine [Moles/volume] in Urine
63
326
2.70
7.51
4.5
2.8
mmol/l
8.0
7.7
0.15
54
274
(3044290) Cell count panel - Cerebral spinal fluid
12
19
6.81
7.37
1.2
1.5
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
71
393
2.64
7.35
7.3
2.8
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
25
77
3.74
7.24
2.9
3.0
e9/l
67.5
69.5
0.10
20
63
(3029937) Albumin [Presence] in Urine by Test strip
57
285
2.69
7.22
8.0
3.6
estimate
0.0
0.0
0.00
37
96
(3023419) Bacteria identified in Sputum by Culture
10
13
8.21
7.21
2.5
2.6
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
62
326
2.62
7.07
6.8
3.7
mg/mmol
12.2
6.0
0.50
45
194
(3012516) Albumin [Mass/volume] in Urine
60
311
2.63
7.04
4.6
3.0
mg/l
933.4
262.1
0.34
41
196
(3018095) Leukocytes [#/volume] in Urine
70
392
2.57
6.98
7.4
3.4
e6/l
61.3
80.8
0.17
55
268
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
75
434
2.57
6.98
6.4
3.8
ng/l
37.2
30.4
0.24
62
277
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
14
28
5.44
6.86
3.4
1.8
—
—
—
0
0
(3026782) Osmolality of Urine
46
212
2.74
6.78
6.2
2.5
mosm/kgh2o
525.7
542.8
0.27
46
180
(3041096) Erythrocytes [Presence] in Urine by Automated
60
317
2.56
6.70
7.7
2.8
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
13
25
5.63
6.63
4.8
2.9
kpa
8.8
8.7
0.02
13
25
(3013290) Carbon dioxide [Partial pressure] in Blood
13
25
5.63
6.63
4.8
2.9
kpa
4.9
5.0
0.10
13
25
(3042936) Bacteria identified in Isolate by Culture
38
161
2.87
6.54
1.8
1.8
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
11
19
6.20
6.21
1.7
5.1
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
14
31
4.91
6.13
3.3
1.7
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
23
75
3.47
6.10
2.4
1.6
—
—
—
0
0
(21494434) Karyotype in Bone marrow
9
6
15.90
5.99
1.1
1.0
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
60
332
2.41
5.92
6.9
2.8
e6/l
23.8
31.5
0.23
53
246
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
11
20
5.88
5.90
5.0
1.4
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
19
56
3.77
5.82
1.6
1.3
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
10
17
6.26
5.71
1.5
2.1
%
91.0
90.0
—
10
17
(3045142) Bone marrow Pathology biopsy report
8
5
16.83
5.47
1.1
1.4
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
8
5
16.83
5.47
1.8
2.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
71
434
2.29
5.46
19.2
7.5
inr
1.4
1.2
1.04
24
125
(3000494) Fungus identified in Specimen by Culture
33
142
2.73
5.44
3.0
1.4
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
23
81
3.20
5.39
9.8
3.2
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
12
26
4.95
5.37
2.3
1.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
39
185
2.54
5.29
1.7
1.7
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
70
431
2.25
5.23
7.6
3.3
—
—
—
0
0
(3013512) EKG study
57
324
2.28
5.15
6.7
3.6
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
8
6
14.03
5.14
1.0
1.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
57
328
2.24
4.97
4.5
2.7
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
29
123
2.71
4.89
1.8
1.5
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
9
10
9.52
4.86
1.6
1.6
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
9
10
9.52
4.86
1.1
1.0
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
9
10
9.52
4.86
1.1
1.0
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
14
38
3.98
4.78
2.9
1.6
—
—
—
0
0
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
14
38
3.98
4.78
2.9
1.6
g/l
4.4
3.8
—
9
24
(3030467) Casts [#/volume] in Urine by Automated count
53
302
2.21
4.68
7.3
2.7
e6/l
0.3
0.6
0.96
47
219
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
7
5
14.63
4.62
1.9
1.6
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
10
21
5.05
4.61
1.5
1.9
—
—
—
0
0
(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
10
22
4.82
4.38
1.3
1.3
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
39
202
2.29
4.29
1.3
1.2
iu/ml
43.7
39.9
0.06
15
77
(3015736) pH of Urine
68
440
2.06
4.23
4.9
3.0
—
—
—
0
0
(4010399)
23
94
2.73
4.14
2.6
1.4
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
17
59
3.14
4.06
4.6
5.9
mmol/l
24.9
25.2
0.11
17
59
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
11
28
4.18
4.06
1.3
1.4
—
—
—
0
0
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
11
28
4.18
4.06
3.2
3.9
mg/l
17.8
27.3
—
6
23
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
7
7
10.44
4.05
1.1
1.0
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
9
14
6.78
4.05
3.0
4.6
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
9
14
6.78
4.05
1.8
1.0
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
10
24
4.41
3.96
1.4
2.1
—
—
—
0
0
(4035726)
24
103
2.61
3.93
1.4
1.4
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
27
123
2.48
3.92
1.9
1.7
—
—
—
0
0
(3000492) Spirometry study
24
104
2.58
3.86
2.0
1.7
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
6
5
12.45
3.80
5.2
2.6
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
6
5
12.45
3.80
5.2
2.6
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
6
5
12.45
3.80
5.2
2.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
26
119
2.46
3.73
2.0
1.6
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
9
16
5.93
3.72
1.4
1.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
24
106
2.53
3.71
6.3
3.6
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
50
301
2.03
3.70
7.1
2.6
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
20
81
2.71
3.66
1.4
1.6
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
7
9
8.11
3.60
1.9
2.3
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
7
9
8.11
3.60
1.9
1.1
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
10
26
4.07
3.59
1.4
1.3
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
9
17
5.58
3.57
1.4
2.1
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
9
17
5.58
3.57
1.4
1.4
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
6
6
10.37
3.53
1.2
2.7
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
7
10
7.30
3.40
1.0
1.0
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
7
10
7.30
3.40
1.9
1.5
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
8
14
5.99
3.39
1.9
1.6
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
30
153
2.22
3.37
1.6
1.5
—
—
—
0
0
(3019225) pH of Specimen
22
98
2.48
3.34
7.4
5.1
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
8
15
5.58
3.24
1.1
1.7
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
6
8
7.77
3.08
5.2
2.0
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
6
8
7.77
3.08
5.2
2.0
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
6
8
7.77
3.08
5.2
2.0
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
6
8
7.77
3.08
5.2
2.0
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
7
12
6.07
3.06
1.0
1.0
—
—
—
0
0
(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
5
5
10.30
3.00
1.4
1.0
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
8
17
4.92
2.96
1.5
1.3
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
9
22
4.30
2.93
2.0
1.1
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
7
13
5.60
2.90
1.4
1.2
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
6
9
6.90
2.89
1.0
1.0
—
—
—
0
0
(4027681)
6
9
6.90
2.89
1.3
1.1
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
6
9
6.90
2.89
1.0
1.1
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
12
42
3.03
2.83
4.0
2.1
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
34
199
1.94
2.64
1.4
1.2
u/ml
0.9
17.9
—
10
75
(40768804) Tissue Pathology biopsy report
67
484
1.74
2.62
2.3
2.1
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
8
20
4.18
2.61
1.9
1.6
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
30
169
1.99
2.59
4.8
2.7
e6/l
5.1
2.9
0.56
17
87
(3026493) Urate [Moles/volume] in Serum or Plasma
46
300
1.79
2.54
2.7
2.5
umol/l
345.3
8480.4
2.05
40
264
(3034770) Mitochondria Ab [Titer] in Serum
9
27
3.49
2.44
1.1
1.1
—
—
—
0
0
(3022313) Gas panel - Capillary blood
12
46
2.76
2.43
7.0
3.2
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
6
12
5.17
2.43
5.2
2.3
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
5
8
6.43
2.39
1.6
1.3
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
8
6.43
2.39
1.0
1.0
—
—
—
0
0
(3038026) Centromere Ab [Units/volume] in Serum
5
8
6.43
2.39
1.6
1.3
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
6
13
4.77
2.29
1.3
1.0
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
6
13
4.77
2.29
5.2
2.2
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
6
13
4.77
2.29
5.2
2.2
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
6
13
4.77
2.29
5.2
2.2
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
6
13
4.77
2.29
5.2
2.2
—
—
—
0
0
(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis
9
29
3.24
2.27
3.9
1.5
g/l
37.1
38.7
—
9
24
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
5
9
5.71
2.23
1.6
1.1
—
—
—
0
0
(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum
5
9
5.71
2.23
1.6
1.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
70
531
1.64
2.16
4.9
3.8
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
10
37
2.83
2.15
1.4
1.3
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
13
56
2.46
2.12
2.4
1.7
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
39
256
1.73
2.07
4.9
3.4
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
10
38
2.76
2.06
8.1
3.7
mmol/l
25.4
25.4
—
10
38
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
40
266
1.71
2.02
2.8
2.2
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
59
436
1.61
1.98
2.4
1.8
pmol/l
86.4
98.3
1.34
31
211
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
8
27
3.08
1.97
3.9
1.6
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
5
11
4.67
1.96
1.4
1.1
—
—
—
0
0
(3019060) Gas panel - Arterial blood
15
72
2.21
1.94
4.2
4.3
—
—
—
0
0
(40758558) Short blood count panel - Blood
43
296
1.65
1.90
13.1
8.3
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
7
22
3.29
1.90
1.1
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
7
22
3.29
1.90
1.1
1.1
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
20
109
1.97
1.89
1.4
2.3
g/l
0.2
0.2
0.31
20
98
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
105
898
1.68
1.88
5.3
4.2
pmol/l
15.1
14.7
0.97
100
823
(3023103) Potassium [Moles/volume] in Serum or Plasma
132
1224
2.37
1.86
27.3
14.7
mmol/l
3.9
4.0
2.95
132
1193
(4268621)
6
17
3.64
1.86
2.8
1.7
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
33
215
1.70
1.79
1.7
3.1
mmol/l
2.4
2.4
0.05
28
191
(4306422)
6
18
3.43
1.76
1.2
1.2
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
8
30
2.76
1.75
1.0
1.1
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
5
13
3.95
1.73
2.6
2.3
—
—
—
0
0
(3020891) Body temperature
10
42
2.49
1.72
5.5
5.0
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
50
366
1.57
1.71
2.9
2.2
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
19
106
1.92
1.69
4.2
7.7
%
95.0
95.3
0.11
19
100
(3022145) Colonoscopy Study observation
25
153
1.77
1.68
1.1
1.3
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
22
130
1.82
1.65
4.9
6.7
mmol/l
103.4
103.8
0.20
22
124
(3020564) Creatinine [Moles/volume] in Serum or Plasma
134
1257
2.54
1.63
33.9
15.2
umol/l
81.3
73.9
1.56
134
1257
(3047007) Chlamydophila sp Ab [Presence] in Serum
5
14
3.66
1.63
1.2
1.1
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
5
14
3.66
1.63
4.8
1.9
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
31
204
1.67
1.61
1.6
1.4
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
7
26
2.78
1.60
1.1
1.4
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
6
20
3.09
1.60
1.5
1.3
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
28
181
1.68
1.56
5.2
2.5
e6/l
0.2
1.3
3.98
16
98
(3024522) Salmonella sp identified in Specimen by Organism specific culture
5
15
3.42
1.53
4.8
1.8
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
5
15
3.42
1.53
4.8
1.8
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
5
15
3.42
1.53
4.8
1.8
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
5
15
3.42
1.53
4.8
1.8
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
5
15
3.42
1.53
4.8
1.8
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
15
3.42
1.53
1.6
1.2
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
131
1221
2.13
1.53
27.1
14.6
mmol/l
139.7
139.8
0.33
131
1191
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
31
207
1.64
1.53
3.4
3.6
ng/l
168.2
86.1
0.39
21
156
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
12
59
2.13
1.48
2.2
1.4
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
5
16
3.20
1.45
5.0
3.3
mmol/l
6.7
7.8
—
5
16
(3019309) Folate [Moles/volume] in Red Blood Cells
28
185
1.64
1.44
1.7
1.6
nmol/l
1151.9
1212.8
0.12
23
149
(3048689) Calprotectin [Mass/mass] in Stool
23
144
1.71
1.43
3.0
1.9
ug/g
101.2
119.2
0.13
18
112
(1761482) Bacteria [#/volume] in Urine by Culture
7
29
2.49
1.41
5.0
4.0
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
10
47
2.21
1.37
6.4
3.1
%
45.7
47.5
—
10
47
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
20
123
1.73
1.33
4.1
7.0
kpa
5.0
5.2
0.82
20
116
(40768797) Stomach Pathology biopsy report
24
156
1.65
1.31
1.1
1.2
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
5
18
2.84
1.29
5.0
3.1
mmol/l
1.6
1.4
—
5
18
(40768443) Skin Pathology biopsy report
11
57
2.01
1.20
1.3
1.2
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
8
39
2.11
1.17
1.9
1.8
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
13
73
1.86
1.15
2.3
3.0
ng/l
99.3
175.8
0.81
13
65
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
118
1082
1.58
1.14
6.1
4.9
mu/l
1.8
1.9
0.44
111
995
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
8
40
2.06
1.14
3.8
5.4
%
1.3
1.6
—
8
35
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
123
1141
1.64
1.10
26.0
12.1
ml/min/173m2
77.8
81.9
1.24
116
927
(3019832) Treponema pallidum Ab [Presence] in Serum
15
90
1.75
1.09
1.5
1.6
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
9
45
2.07
1.07
3.7
2.5
%
1.4
1.5
—
9
45
(3023323) Follitropin [Units/volume] in Serum or Plasma
9
45
2.07
1.07
1.2
1.3
iu/l
41.6
22.2
—
9
38
(3044889) 12 lead EKG panel
95
841
1.40
1.06
5.2
3.8
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
8
42
1.96
0.90
2.9
2.4
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
119
1110
1.48
0.87
7.1
5.5
mmol/mol
40.5
39.5
0.55
113
1041
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
6
33
1.85
0.80
1.7
1.2
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
33
1.85
0.80
2.2
1.2
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
24
0.00
0.80
0.0
1.6
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
108
996
1.37
0.80
36.1
16.1
%
14.0
13.6
4.05
108
983
(3013139) Helicobacter pylori Ag [Presence] in Stool
11
67
1.70
0.77
1.2
1.2
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
23
2.22
0.77
1.6
1.4
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
23
2.22
0.77
1.6
1.4
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
5
23
2.22
0.77
1.2
1.0
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
9
54
1.71
0.76
4.4
2.4
—
—
—
0
0
(40761535) Cells panel - Urine sediment
13
84
1.60
0.75
7.5
3.1
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
17
236
0.68
0.73
4.5
4.3
%
18.1
21.4
0.50
11
98
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
7
118
0.57
0.71
1.9
1.8
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
7
44
1.62
0.66
2.0
1.3
—
—
—
0
0
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
0
20
0.00
0.61
0.0
1.1
—
2.4
—
0
13
(40768800) Prostate Pathology biopsy report
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
26
204
1.34
0.60
1.8
1.4
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
89
815
1.25
0.59
3.9
2.9
u/l
65.3
50.1
0.52
83
771
(1002224) Polysomnography panel
8
54
1.51
0.58
1.0
1.1
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
13
90
1.49
0.58
2.5
3.0
ml/min/173m2
59.4
67.4
—
7
35
(3019150) Specific gravity of Urine by Refractometry
30
243
1.30
0.56
7.4
3.6
kg/l
1.0
1.0
—
5
32
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
6
40
1.52
0.52
1.7
1.1
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
6
40
1.52
0.52
1.8
1.1
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
6
40
1.52
0.52
1.7
1.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
38
321
1.25
0.51
1.5
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
82
756
1.20
0.46
3.9
3.0
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
9
126
0.69
0.46
11.3
8.5
—
—
—
0
0
(4094501)
5
31
1.63
0.43
1.2
1.1
—
—
—
0
0
(4281824)
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
10
71
1.44
0.40
1.4
1.2
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
9
67
1.37
0.39
1.4
1.3
—
—
—
0
0
(3043409) Potassium [Moles/volume] in Arterial blood
5
36
1.40
0.38
8.2
4.3
mmol/l
3.6
3.8
—
5
30
(3008152) Bicarbonate [Moles/volume] in Arterial blood
10
72
1.42
0.38
9.4
7.7
mmol/l
24.9
25.4
—
10
65
(40761511) CBC panel - Blood by Automated count
128
1244
1.34
0.37
24.2
12.0
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
52
471
1.17
0.34
3.3
2.8
—
—
—
0
0
(3008898) HLA-B27 [Presence]
6
47
1.29
0.32
1.0
1.1
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
6
47
1.29
0.32
1.2
1.0
—
—
—
0
0
(3000991) Gas panel - Venous blood
11
84
1.34
0.31
7.3
6.9
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
7
56
1.26
0.30
1.0
1.0
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
7
56
1.26
0.30
9.7
2.7
—
—
—
0
0
(3000963) Hemoglobin [Mass/volume] in Blood
134
1315
1.44
0.24
45.2
19.6
g/l
134.2
136.2
0.91
134
1296
(3024731) MCV [Entitic volume]
134
1315
1.44
0.24
44.6
19.4
fl
91.6
91.2
0.47
134
1295
(3035941) MCH [Entitic mass]
134
1315
1.44
0.24
44.4
19.4
pg
30.2
30.3
0.32
134
1295
(3009542) Hematocrit [Volume Fraction] of Blood
105
1083
0.88
0.22
26.6
14.0
%
40.5
40.3
0.09
78
841
(36660697) Celiac disease serology panel - Serum
11
89
1.26
0.21
1.4
1.2
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
25
222
1.15
0.21
1.5
1.7
pmol/l
428.6
476.4
0.62
20
194
(3005570) Glucose [Moles/volume] in Urine
0
13
0.00
0.21
0.0
3.1
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
13
110
1.20
0.18
1.5
1.3
—
—
—
0
0
(3022621) pH of Urine by Test strip
7
87
0.79
0.15
4.1
2.6
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
11
93
1.20
0.15
2.0
1.8
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
118
1158
1.12
0.14
6.0
4.4
mmol/l
5.9
5.9
0.05
111
1079
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
12
104
1.17
0.13
2.2
2.0
—
—
—
0
0
(3002256) Pathology report gross observation
16
143
1.13
0.12
1.4
1.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
12
136
0.87
0.11
1.2
1.4
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
54
1.12
0.09
2.8
7.1
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
15
139
1.09
0.05
5.2
4.0
%
33.5
33.2
0.03
15
90
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
13
133
0.98
0.00
1.3
1.7
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
9
0.00
0.00
0.0
3.1
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
9
0.00
0.00
0.0
3.1
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
6
65
0.92
0.00
1.8
1.8
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
27.9
—
0
5
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
5
54
0.92
0.00
1.2
1.6
—
—
—
0
0
(4211845)
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_CHURGSTRAUSS and mortality.

Females

Parameter HR [95% CI] p-value
M13_CHURGSTRAUSS 1.776 [1.31, 2.4] < 0.001
Birth year 0.997 [0.99, 1.01] 0.509

During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 338 females with M13_CHURGSTRAUSS died.

Males

Parameter HR [95% CI] p-value
M13_CHURGSTRAUSS 1.771 [1.23, 2.56] 0.002
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 192 males with M13_CHURGSTRAUSS died.

Mortality risk

Mortality risk for people of age

years, who have M13_CHURGSTRAUSS.

N-year risk Females Males
1 0.195% 0.339%
5 1.128% 2.094%
10 2.675% 5.255%
15 5.195% 9.979%
20 9.422% 16.502%

Relationships between endpoints

Index endpoint: M13_CHURGSTRAUSS – Polyarteritis with lung involvement [Churg-Strauss]/EGPA

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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