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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of endometrium

CD2_INSITU_ENDOMETRIUM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D07.0&
  • Hospital discharge: ICD-9 2332
  • Cause of death: ICD-10 D07.0&
  • Cause of death: ICD-9 2332

2 out of 7 registries used, show all original rules.

168

4. Check minimum number of events

None

168

5. Include endpoints

None

168

6. Filter based on genotype QC (FinnGen only)

162

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D07
Name in latin
Carcinoma in situ endometrii (corporis uteri)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 162 162 -
Unadjusted period prevalence (%) 0.06 0.06 -
Median age at first event (years) 62.35 62.35 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
168
Matched controls
1680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D07.0
ICD-10 Finland
Carcinoma in situ: Endometrium
+∞
239.8
167
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
94.3
171.4
97
24
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
89.0
158.0
89
21
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
38.2
131.8
106
72
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
73.6
118.4
67
15
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
358.5
70.0
66
*
N95.0
ICD-10 Finland
Postmenopausal bleeding
10.5
52.7
85
149
B01AB10
ATC
tinzaparin; parenteral
9.8
46.2
72
119
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
9.9
35.5
48
65
N84.0
ICD-10 Finland
Polyp of corpus uteri
8.0
34.5
60
109
N85.1
ICD-10 Finland
Endometrial adenomatous hyperplasia
37.3
30.1
38
13
ZXC96
NOMESCO Finland
Robot assisted procedure
20.7
19.0
28
16
WF003
NOMESCO Finland
Adjuvant radiotherapy
8.3
17.0
24
33
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
13.2
16.0
28
25
SPAT1312
SPAT
General health counselling
3.5
14.3
86
390
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
4.7
13.7
37
96
ULC02
NOMESCO Finland
Hysteroscopy
4.7
11.4
29
71
JN4BD
NOMESCO Finland
Extensive body CT
3.8
11.0
39
123
8380/3-C54.9
ICD-O-3
Endometrioid adenocarcinoma, NOS, of corpus uteri
23.3
10.9
15
7
SPAT1249
SPAT
Treatment-related counselling outside office
3.0
10.8
93
497
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
4.9
10.7
26
61
LCA06
NOMESCO Finland
Biopsy of endometrium
3.3
10.7
50
189
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
17.5
10.6
16
10
TLC00
NOMESCO Finland
Insertion of intrauterine device
5.8
10.4
20
38
SPAT1301
SPAT
No procedures
2.7
9.3
78
404
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
39.0
9.1
11
*
B01AB05
ATC
enoxaparin; parenteral
2.7
8.9
83
450
C54.10
ICD-10 Finland
Malignant tumor of endometrium without histology
52.8
8.8
10
*
UJF32
NOMESCO Finland
Coloscopy
2.7
8.7
66
322
SPAT1260
SPAT
Consultation of another employee
2.9
8.5
49
207
WF090
NOMESCO Finland
Profylactic radiotherapy
+∞
8.4
8
*
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
15.5
8.3
13
9
SPAT1310
SPAT
Counselling related to known health issue
2.6
8.0
76
411
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
3.6
8.0
29
92
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
4.4
7.6
20
50
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.5
7.5
74
405
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.0
7.3
22
61
WX408
NOMESCO Finland
General anesthesy, balanced
0.2
7.2
6
306
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.4
6.9
67
362
128
Kela drug reimbursment
Cancers of female genital organs
6.0
6.8
18
33
LCB14
NOMESCO Finland
Laparoscopic myolysis
13.0
6.7
11
9
E66.01
ICD-10 Finland
Obesity due to excess calories
3.3
6.4
26
88
ZXE00
NOMESCO Finland
One hour or less
0.3
6.4
20
519
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.0
6.4
19
52
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
7.5
6.4
14
20
YX9VG
NOMESCO Finland
Other MRI eamination with high intensity magnet for dose design of radiotherapy
+∞
6.3
6
*
SPAT1153
SPAT
Removal of sutures
2.3
6.2
71
407
LCD11
NOMESCO Finland
Laparoscopically assisted vaginal hysterectomy
6.8
6.0
14
22

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
76
125
10.28
49.31
4.3
3.2
—
—
—
0
0
44
51
11.33
36.65
4.0
5.1
—
—
—
0
0
116
391
7.35
35.61
5.6
4.5
0.00
0.00
estimate
-0.00
18
143
105
349
6.36
31.85
5.8
4.0
—
—
—
0
0
63
131
7.09
31.63
1.4
2.2
0.24
0.21
g/l
2.43
63
124
47
90
6.86
25.13
6.2
8.0
24.56
25.79
mmol/l
1.67
47
84
48
95
6.67
24.82
3.7
5.2
—
—
—
0
0
42
76
7.04
23.63
4.0
7.6
95.15
94.90
%
0.23
42
76
116
584
4.19
17.29
5.9
4.0
—
5.88
—
0
36
131
748
4.41
15.61
5.8
4.2
0.00
0.02
estimate
0.50
18
136
129
742
4.18
14.89
5.9
4.1
0.00
0.00
estimate
-0.00
18
153
129
744
4.16
14.78
6.4
5.6
0.00
0.00
estimate
-0.00
15
137
47
140
4.27
14.61
3.8
6.5
97.86
96.18
%
3.40
47
132
50
158
4.08
14.32
3.7
6.3
13.54
12.53
kpa
0.66
50
152
50
158
4.08
14.32
3.7
6.3
5.25
5.30
kpa
0.12
50
152
50
162
3.97
13.78
3.7
6.2
1.28
1.86
mmol/l
0.93
36
136
124
717
3.79
13.68
2.3
2.3
—
—
—
0
0
115
653
3.41
12.66
3.4
3.6
37.04
35.59
g/l
2.94
107
608
42
137
3.75
11.29
2.0
1.5
—
—
—
0
0
140
1056
2.95
6.73
5.3
3.8
—
—
—
0
0
17
43
4.29
6.34
22.1
7.8
—
—
—
0
0
130
1036
2.13
4.09
5.3
4.8
—
69.07
—
0
14
61
380
1.95
3.97
1.2
1.3
—
—
—
0
0
80
547
1.88
3.92
4.7
3.5
18.78
31.79
ng/l
0.81
57
385
62
393
1.92
3.81
6.0
6.8
—
—
—
0
0
94
707
1.75
3.14
3.7
4.7
1.17
1.22
mmol/l
7.51
85
634
5
5
10.25
2.99
2.0
2.0
—
—
—
0
0
24
437
0.47
2.95
2.5
3.1
21.36
36.87
e6/l
0.73
19
337
85
630
1.71
2.92
2.3
2.1
—
—
—
0
0
25
447
0.48
2.91
1.4
1.6
1.51
1.32
mmol/l
0.40
20
371
162
1499
3.26
2.74
14.6
13.0
—
—
—
0
0
62
438
1.66
2.46
2.9
2.9
22.80
192.34
mg/l
0.52
40
250
138
1207
1.80
2.25
5.5
4.4
15.44
14.83
pmol/l
1.95
129
1097
104
847
1.60
2.24
4.3
4.1
6.78
6.57
mmol/l
0.53
98
784
75
569
1.57
2.17
3.4
3.1
—
—
—
0
0
157
1441
2.37
2.10
16.6
13.7
26.07
21.18
mg/l
0.70
131
1122
26
150
1.87
2.05
1.3
1.6
—
—
—
0
0
63
468
1.55
1.96
3.2
3.4
6.04
5.39
mg/mmol
0.05
41
260
61
450
1.56
1.96
2.7
2.8
7.21
6.33
mmol/l
1.11
55
363
5
11
4.65
1.95
4.0
1.3
—
—
—
0
0
47
332
1.58
1.80
1.6
1.6
0.73
0.98
mg/l
0.90
37
257
30
449
0.60
1.80
4.1
3.6
—
—
—
0
0
22
357
0.56
1.78
2.3
3.1
86.27
95.88
%
0.76
22
346
149
1360
1.85
1.75
4.6
4.1
1.35
1.24
mmol/l
1.38
136
1229
94
774
1.49
1.74
4.1
5.6
1.17
1.23
mmol/l
6.87
82
658
104
875
1.50
1.73
7.7
8.9
4.09
3.97
e9/l
0.22
97
772
38
532
0.63
1.71
2.7
3.7
19.06
109.14
e6/l
3.42
30
372
32
465
0.61
1.69
2.7
3.1
—
—
—
0
0
20
114
1.86
1.65
1.5
1.5
—
—
—
0
0
161
1525
2.34
1.52
18.7
16.1
70.61
69.47
umol/l
0.25
161
1525
157
1471
2.03
1.47
5.7
5.2
2.80
2.81
mmol/l
0.07
145
1348
23
350
0.60
1.45
1.3
1.2
0.67
1.47
u/ml
0.72
12
95
0
41
0.00
1.33
0.0
4.6
—
37.46
—
0
34
31
214
1.55
1.30
1.5
2.0
—
—
—
0
0
148
1373
1.65
1.30
6.6
5.7
41.03
39.58
mmol/mol
1.10
139
1268
29
407
0.65
1.27
3.9
3.7
—
—
—
0
0
153
1434
1.75
1.25
5.5
4.7
6.22
5.88
mmol/l
2.96
145
1311
153
1442
1.68
1.11
5.1
4.6
4.73
4.84
mmol/l
0.73
142
1324
10
178
0.53
1.11
1.3
1.6
—
—
—
0
0
45
351
1.39
1.03
3.4
3.7
—
—
—
0
0
16
100
1.66
1.01
1.3
1.3
—
—
—
0
0
0
29
0.00
0.98
0.0
2.6
—
—
—
0
0
0
30
0.00
0.98
0.0
1.0
—
—
—
0
0
0
30
0.00
0.98
0.0
1.6
—
1.25
—
0
23
43
336
1.38
0.97
2.1
2.4
323.89
9181.45
umol/l
2.51
37
290
0
32
0.00
0.96
0.0
5.4
—
—
—
0
0
125
1150
1.34
0.88
5.9
7.1
79.57
77.70
u/l
0.16
119
1058
11
65
1.74
0.84
1.6
2.2
0.93
0.68
%
1.23
11
65
163
1583
2.00
0.81
26.9
20.6
40.33
39.42
%
2.12
157
1474
148
1404
1.45
0.80
6.4
5.3
2.63
1.91
mu/l
0.82
139
1283
10
161
0.60
0.80
1.3
1.5
—
—
—
0
0
0
24
0.00
0.80
0.0
1.5
—
—
—
0
0
150
1427
1.48
0.79
4.9
4.5
1.52
1.62
mmol/l
2.15
138
1303
0
27
0.00
0.78
0.0
2.2
—
5.31
—
0
27
0
27
0.00
0.78
0.0
2.9
—
62.93
—
0
27
10
59
1.74
0.77
1.3
1.2
—
—
—
0
0
57
666
0.78
0.76
1.9
2.0
96.76
101.01
pmol/l
0.39
41
289
5
24
2.12
0.75
1.0
1.1
—
—
—
0
0
11
68
1.66
0.73
1.6
2.2
1.33
1.12
%
0.38
11
68
26
199
1.36
0.67
1.4
1.6
26.64
29.11
s
2.11
26
191
8
126
0.62
0.67
1.3
1.3
—
—
—
0
0
65
570
1.23
0.60
3.1
3.2
2.39
2.37
mmol/l
0.66
58
488
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
55
475
1.23
0.59
1.8
2.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
5
88
0.56
0.58
1.0
1.8
1.19
1.61
g/l
—
5
80
9
63
1.45
0.53
1.4
4.8
1.48
1.55
%
—
9
58
77
698
1.19
0.49
37.4
11.3
1.10
1.18
inr
0.29
11
199
10
68
1.50
0.48
1.6
3.1
24.86
25.77
mmol/l
—
10
68
8
118
0.66
0.47
2.4
4.2
—
—
—
0
0
59
657
0.84
0.45
8.8
8.9
0.00
0.00
e9/l
0.37
53
541
36
306
1.22
0.45
1.6
1.6
465.24
475.17
pmol/l
0.07
29
247
34
398
0.82
0.44
2.6
2.8
—
—
—
0
0
6
94
0.63
0.43
1.3
1.3
—
—
—
0
0
13
171
0.74
0.42
1.2
1.8
48.46
129.29
ug/g
1.66
13
131
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
202.25
—
0
19
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
12
89
1.38
0.39
1.4
1.3
—
—
—
0
0
8
113
0.69
0.38
3.3
2.5
8.98
10.09
g/l
—
8
104
14
178
0.77
0.36
1.2
1.2
—
—
—
0
0
41
365
1.16
0.32
2.3
2.0
4.96
3.33
mg/l
1.85
36
306
65
698
0.89
0.28
5.6
5.8
—
—
—
0
0
33
292
1.16
0.28
1.2
1.3
11.83
11.89
u/ml
0.00
22
114
54
501
1.11
0.23
2.7
3.3
7.39
7.40
ph
—
7
91
116
1121
1.11
0.22
5.4
4.4
15.72
12.92
mm/h
1.16
107
1017
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
1.83
—
0
10
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
18.61
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
225.56
—
0
9
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
24
213
1.15
0.20
1.0
1.2
—
—
—
0
0
11
91
1.22
0.18
1.8
6.2
—
—
—
0
0
16
183
0.86
0.17
1.4
1.2
—
—
—
0
0
5
70
0.71
0.17
2.6
5.2
24.60
25.79
mmol/l
—
5
70
67
638
1.08
0.16
2.4
2.6
112.64
90.86
ug/l
0.53
62
584
11
93
1.20
0.15
1.6
1.2
—
—
—
0
0
27
293
0.91
0.13
1.3
1.3
31.67
40.14
iu/ml
—
10
98
78
753
1.07
0.12
5.7
5.2
1.75
1.89
e9/l
0.60
72
672
13
147
0.87
0.12
2.2
3.6
—
—
—
0
0
11
125
0.87
0.10
1.5
3.2
—
—
—
0
0
76
739
1.05
0.09
5.3
5.2
0.52
0.56
e9/l
0.62
69
641
13
144
0.89
0.08
1.4
1.4
—
—
—
0
0
5
62
0.80
0.08
2.0
1.7
—
—
—
0
0
76
740
1.05
0.08
5.3
5.2
0.03
0.04
e9/l
0.71
69
640
14
127
1.11
0.08
3.4
4.4
1.67
1.00
%
—
6
44
8
75
1.07
0.07
2.4
2.1
—
—
—
0
0
7
82
0.85
0.07
1.7
1.3
—
—
—
0
0
13
138
0.94
0.02
2.2
2.0
425.62
370.66
nmol/l
0.86
13
131
76
768
0.98
0.01
5.8
5.4
0.18
0.18
e9/l
0.04
70
675
105
1057
0.98
0.01
4.3
4.7
—
—
—
0
0
12
119
1.01
0.00
1.2
1.6
—
—
—
0
0
18
183
0.98
0.00
1.4
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
29.43
—
0
7
0
7
0.00
0.00
0.0
3.4
—
51.86
—
0
7
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
-0.00
2.1
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
79.58
—
0
5
5
55
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
1.04
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
53
0.94
-0.00
2.0
6.3
1.28
1.11
mmol/l
—
5
47
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
40.72
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
10.24
—
0
8
7
76
0.92
-0.00
1.4
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
63.25
—
0
8
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
15.0
—
1553.17
—
0
6
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.0
—
860.83
—
0
6
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.54
—
0
5
0
6
0.00
-0.00
0.0
22.5
—
77.67
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_ENDOMETRIUM – Carcinoma in situ of endometrium

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).