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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_INSITU_DIGESTIVE_EXALLC for full statistics.

Carcinoma in situ of other and unspecified digestive organs

DOID Endpoint Browser

CD2_INSITU_DIGESTIVE

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D01
  • Cause of death: ICD-10 — D01

2 out of 7 registries used, show all original rules.

129

4. Check minimum number of events

None

129

5. Include endpoints

831

6. Filter based on genotype QC (FinnGen only)

831

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D00-D09
Name in latin
Carcinoma in situ organorum digestoriorum aliorum sive non specificatorum

Similar endpoints

↥

List of similar endpoints to Carcinoma in situ of other and unspecified digestive organs based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 831 350 481
Unadjusted period prevalence (%) 0.17 0.12 0.21
Median age at first event (years) 69.88 69.02 70.50

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
745
Matched controls
7448
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
11.7
137.9
285
373
UJF32
NOMESCO Finland
Coloscopy
7.0
130.5
465
1421
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
18.0
128.9
211
160
8263/2-C20.9
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of rectum, NOS
+∞
99.2
93
*
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
10.9
86.3
177
207
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
16.7
71.2
117
82
WX402
NOMESCO Finland
General anaesthesia
5.2
68.8
255
677
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
8.2
62.9
151
224
C209, 8211, 2
ICD-O-3
NA
+∞
59.2
56
*
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
12.7
59.1
109
99
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
19.0
56.7
88
52
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
17.7
55.2
88
56
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
12.0
55.0
104
99
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
15.1
54.1
92
69
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
8.2
53.8
127
181
WX302
NOMESCO Finland
Thoracal epidural anesthesy
7.3
53.3
137
222
C209, 8148, 2
ICD-O-3
NA
+∞
51.7
49
*
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
19.0
47.8
74
43
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.8
43.6
135
276
D01.0
ICD-10 Finland
Carcinoma in situ: Colon
+∞
43.1
41
*
8263/2-C18.0
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of cecum
441.7
42.6
42
*
C187, 8211, 2
ICD-O-3
NA
+∞
42.1
40
*
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
25.2
38.5
54
23
B01AB05
ATC
enoxaparin; parenteral
2.8
37.6
338
1684
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
16.1
37.3
61
41
D01.2
ICD-10 Finland
Carcinoma in situ: Rectum
363.6
35.3
35
*
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
49.9
31.8
38
8
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
8.5
31.7
71
91
8263/2-C18.7
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of sigmoid colon
+∞
31.5
30
*
C189, 8211, 2
ICD-O-3
NA
+∞
31.5
30
*
K63.5
ICD-10 Finland
Polyp of colon
14.2
30.4
52
39
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
11.6
29.3
55
51
C180, 8211, 2
ICD-O-3
NA
+∞
26.2
25
*
L01BC06
ATC
capecitabine; oral
6.2
25.6
71
124
8263/2-C18.9
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of colon, NOS
+∞
25.1
24
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
24.7
145
521
UJF32
SPAT
NA
11.6
24.7
46
42
JFF23
NOMESCO Finland
Transversostomy
14.4
24.3
41
30
130
Kela drug reimbursment
Malignant tumour
3.6
23.7
116
363
JGA73
NOMESCO Finland
Transanal excision of lesion of rectum
48.4
23.5
28
6
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
15.2
21.4
35
24
WX600
NOMESCO Finland
Single shot through catheter
12.5
21.2
38
32
JGB03
NOMESCO Finland
Partial proctectomy with partial excision of mesorectum
51.6
21.2
25
5
C187, 8148, 2
ICD-O-3
NA
+∞
20.9
20
*
UJF30
NOMESCO Finland
Ileoscopy through colon
3.3
20.9
116
398
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
20.8
20.5
30
15
B01AB10
ATC
tinzaparin; parenteral
3.7
20.4
96
290
R4110
NOMESCO Finland
Physiotherapy
2.2
19.7
248
1358
JN4AD
NOMESCO Finland
Body CT examination
3.3
19.3
106
358
C189, 8148, 2
ICD-O-3
NA
+∞
18.8
18
*
UJG02
NOMESCO Finland
Proctoscopy
7.8
18.7
43
58
C20.99
ICD-10 Finland
Malignant tumor of the rectum other or unspecified histology
32.3
17.1
22
7
JG1BG
NOMESCO Finland
MRI of rectum
26.3
17.0
23
9
JG1CG
NOMESCO Finland
Extensive MRI of rectum
14.5
16.9
28
20
8211/2-C18.2
ICD-O-3
Tubular adenocarcinoma in situ of ascending colon
+∞
16.7
16
*
C180, 8148, 2
ICD-O-3
NA
+∞
16.7
16
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
16.5
264
1581
JFA15
SPAT
NA
20.6
16.5
24
12
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
16.3
196
1034
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.8
16.0
69
193
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
7.3
15.5
37
53
JGA75
NOMESCO Finland
Endoscopic microsurgical excision of lesion of rectum
57.9
14.8
17
*
8263/2-C18.2
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of ascending colon
+∞
14.6
14
*
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
8.5
14.4
31
38
C20
ICD-10 Finland
Malignant neoplasm of rectum
17.4
14.4
22
13
JGA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in rectum
43.4
14.2
17
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
13.7
177
956
8140/2-C20.9
ICD-O-3
Adenocarcinoma in situ, NOS, of rectum, NOS
+∞
13.6
13
*
JFA52
NOMESCO Finland
Other endoscopic haemostatic procedure in colon
26.3
13.4
18
7
JN4BD
NOMESCO Finland
Extensive body CT
2.4
13.3
120
548
WZC30
NOMESCO Finland
Teaching
2.3
13.2
128
607
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
13.1
115
519
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
50.9
12.9
15
*
C209, 8213, 2
ICD-O-3
NA
+∞
12.5
12
*
C21.1
ICD-10 Finland
Malignant neoplasm: Anal canal
132.1
12.5
13
*
D12.9
ICD-10 Finland
Benign neoplasm: Anus and anal canal
11.9
12.4
22
19
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
14.6
12.3
20
14
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.4
12.2
60
188
K62.1
ICD-10 Finland
Rectal polyp
7.9
11.7
26
34
Z71.8
ICD-10 Finland
Other specified counselling
2.0
11.5
177
1019
8140/2-C18.7
ICD-O-3
Adenocarcinoma in situ, NOS, of sigmoid colon
+∞
11.5
11
*
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
7.8
11.2
25
33
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
20.4
11.2
16
8
C18.00
ICD-10 Finland
Malignant tumor of the caecum without histology
8.2
11.1
24
30
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.0
11.0
43
112
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.8
10.9
46
128
TJF80
NOMESCO Finland
Ostomy education
8.4
10.9
23
28
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
6.3
10.8
28
46
C21.0
ICD-10 Finland
Malignant neoplasm: Anus, unspecified
28.5
10.8
14
5
JFB44
NOMESCO Finland
Laparoscopic left hemicolectomy
21.8
10.7
15
7
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
10.5
286
1981
JFB30
NOMESCO Finland
Right hemicolectomy
5.8
10.5
29
52
C188, 8211, 2
ICD-O-3
NA
+∞
10.4
10
*
D01.1
ICD-10 Finland
Carcinoma in situ: Rectosigmoid junction
+∞
10.4
10
*
TQW40
NOMESCO Finland
Remowal of suture of skin
2.8
10.2
67
255
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.5
10.2
47
141
N02BE01
ATC
paracetamol; systemic, rectal
1.9
10.1
639
5634
JFF10
NOMESCO Finland
Loop enterostomy
17.0
9.9
15
9
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
9.5
68
274
C186, 8211, 2
ICD-O-3
NA
+∞
9.4
9
*
D01.3
ICD-10 Finland
Carcinoma in situ: Anus and anal canal
+∞
9.4
9
*
C184, 8211, 2
ICD-O-3
NA
+∞
9.4
9
*
C184, 8148, 2
ICD-O-3
NA
+∞
9.4
9
*
D75
ICPC
Malignant neoplasm colon/rectum
8.8
9.3
19
22
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
9.2
125
680
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
13.9
9.2
15
11
JGB07
NOMESCO Finland
Laparoscopic partial proctectomy with total excision of mesorectum
15.8
9.1
14
9
JGB00
NOMESCO Finland
Partial proctectomy and colorectal or coloanal anastomosis
18.9
9.0
13
7
WX002
NOMESCO Finland
Sedation and analgesia
1.8
8.9
163
993
Z3231
NOMESCO Finland
Registered nurse
1.7
8.6
212
1412
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
8.6
240
1655
Z93.3
ICD-10 Finland
Colostomy status
9.1
8.6
17
19
C182, 8148, 2
ICD-O-3
NA
+∞
8.3
8
*
JFB51
NOMESCO Finland
Other laparoscopic resection of colon
+∞
8.3
8
*
A02BC02
ATC
pantoprazole; systemic
1.6
8.3
476
3932
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
3.8
8.2
33
89
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
8.2
154
940
C18.01
ICD-10 Finland
Malignant tumor of the caecum invasive carcinoma
7.4
8.0
18
25
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
7.9
96
501
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
8.6
7.8
16
19
D12
ICD-10 Finland
Benign neoplasm of colon, rectum, anus and anal canal
10.9
7.8
14
13
ZXE00
NOMESCO Finland
One hour or less
1.6
7.8
279
2044
WX892
NOMESCO Finland
Monitored bed care
2.3
7.8
68
306
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
7.7
153
953
8140/3-C18.9
ICD-O-3
Adenocarcinoma, NOS, of colon, NOS
12.0
7.6
13
11
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
12.0
7.6
13
11
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
7.4
279
2057
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
7.4
71
334
8077/2-C21.0
ICD-O-3
Squamous intraepithelial neoplasia, high grade of anus, NOS
+∞
7.3
7
*
JGB20
NOMESCO Finland
Partial rectosigmoidectomy and abdominoperineal pull-through anastomosis
+∞
7.3
7
*
D01.5
ICD-10 Finland
Carcinoma in situ: Liver, gallbladder and bile ducts
+∞
7.3
7
*
Z2221
NOMESCO Finland
Medical doctor
1.6
7.3
197
1334
WF001
NOMESCO Finland
Preoperative radiotherapy
6.3
7.3
18
29
R4190
NOMESCO Finland
Nutritional therapy
3.9
7.2
28
74
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
7.2
69
324
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
7.1
204
1405
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
20.2
7.1
10
5
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
20.2
7.1
10
5
WX110
NOMESCO Finland
Local anesthesy
1.5
7.1
452
3756
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
6.9
149
946
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.1
6.9
36
121
8140/3-C18.2
ICD-O-3
Adenocarcinoma, NOS, of ascending colon
8.4
6.8
14
17
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
11.1
6.8
12
11
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
9.4
6.8
13
14
JAH00
NOMESCO Finland
Laparotomy
3.5
6.8
30
89
C18.02
ICD-10 Finland
Malignant tumor of caecum carcinoma of adenoma
40.4
6.8
8
*
D18
ICPC
Change in faeces/bowel movements
3.6
6.7
28
79
WF002
NOMESCO Finland
Radical radiotherapy
2.4
6.7
53
226
SPAT1125
SPAT
Stoma care and guidance
4.4
6.6
22
51
A04AA02
ATC
granisetron; systemic, transdermal
2.4
6.6
52
222
K92.1
ICD-10 Finland
Melaena
2.4
6.4
52
227
JFA42
NOMESCO Finland
Endoscopic injection in colon
14.5
6.4
10
7
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
5.2
6.3
18
35
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
8.2
6.3
13
16
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
11.1
6.3
11
10
D01.7
ICD-10 Finland
Carcinoma in situ: Other specified digestive organs
+∞
6.3
6
*
8480/3-C20.9
ICD-O-3
Mucinous adenocarcinoma of rectum, NOS
+∞
6.3
6
*
8263/2-C18.4
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of transverse colon
+∞
6.3
6
*
TJG20
NOMESCO Finland
Transanal irrigation
26.9
6.2
8
*
JHA00
NOMESCO Finland
Anal or perianal incision
6.4
6.2
15
24
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
8.7
6.1
12
14
C18.21
ICD-10 Finland
Malignant tumor of the ascending colon invasive carcinoma
6.8
6.1
14
21

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_DIGESTIVE – Carcinoma in situ of other and unspecified digestive organs

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).