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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_INSITU_COLON_EXALLC for full statistics.

Carcinoma in situ of colon

CD2_INSITU_COLON

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • not C3_COLON
514270

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D01.0&
  • Hospital discharge: ICD-9 2303
  • Cause of death: ICD-10 D01.0&
  • Cause of death: ICD-9 2303
  • Cancer registry: Topography ICD-O-3 C18
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

438

4. Check minimum number of events

None

438

5. Include endpoints

None

438

6. Filter based on genotype QC (FinnGen only)

438

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D01
Name in latin
Carcinoma in situ ani

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 438 175 263
Unadjusted period prevalence (%) 0.09 0.06 0.12
Median age at first event (years) 71.38 71.88 71.04

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
393
Matched controls
3928
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UJF32
NOMESCO Finland
Coloscopy
8.8
84.8
262
728
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
22.6
58.3
86
48
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
15.2
57.2
99
85
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
12.0
53.5
104
114
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
11.1
52.6
107
128
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
37.5
51.9
66
21
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
15.4
48.2
82
66
8263/2-C18.0
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of cecum
+∞
43.5
41
*
C187, 8211, 2
ICD-O-3
NA
+∞
42.5
40
*
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
17.2
36.7
59
40
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
6.5
35.3
101
198
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
20.2
35.2
53
30
C189, 8211, 2
ICD-O-3
NA
+∞
31.7
30
*
8263/2-C18.7
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of sigmoid colon
+∞
31.7
30
*
K63.5
ICD-10 Finland
Polyp of colon
30.3
30.9
41
15
WX402
NOMESCO Finland
General anaesthesia
4.5
30.6
128
381
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
12.3
28.8
53
49
WX302
NOMESCO Finland
Thoracal epidural anesthesy
7.1
25.6
66
109
C180, 8211, 2
ICD-O-3
NA
+∞
25.3
24
*
8263/2-C18.9
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of colon, NOS
+∞
25.3
24
*
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
13.3
24.4
43
36
B01AB05
ATC
enoxaparin; parenteral
3.0
22.1
179
860
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.8
21.9
65
129
C187, 8148, 2
ICD-O-3
NA
+∞
21.0
20
*
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
6.8
20.7
54
90
C189, 8148, 2
ICD-O-3
NA
+∞
18.9
18
*
UJF32
SPAT
NA
12.3
18.9
34
30
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.2
18.6
118
466
8211/2-C18.2
ICD-O-3
Tubular adenocarcinoma in situ of ascending colon
+∞
16.8
16
*
C180, 8148, 2
ICD-O-3
NA
+∞
16.8
16
*
JFA15
SPAT
NA
35.0
15.9
20
6
D01.0
ICD-10 Finland
Carcinoma in situ: Colon
166.3
15.6
16
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
7.3
15.4
37
55
UJF30
NOMESCO Finland
Ileoscopy through colon
3.7
15.0
71
223
TPH07
NOMESCO Finland
Cathetrisation of artery
3.4
14.8
80
277
8263/2-C18.2
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of ascending colon
+∞
14.7
14
*
B01AB10
ATC
tinzaparin; parenteral
4.2
14.0
56
151
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
15.8
13.2
21
14
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
7.3
12.7
30
44
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
48.2
11.9
14
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
9.4
11.9
24
27
8140/2-C18.7
ICD-O-3
Adenocarcinoma in situ, NOS, of sigmoid colon
+∞
11.5
11
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
11.2
145
820
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
5.3
10.9
33
67
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
9.6
10.6
21
23
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
10.5
10.6
20
20
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.5
10.2
48
149
JFB44
NOMESCO Finland
Laparoscopic left hemicolectomy
20.7
9.9
14
7
JN4AD
NOMESCO Finland
Body CT examination
3.0
9.7
56
203
C188, 8211, 2
ICD-O-3
NA
+∞
9.4
9
*
C186, 8211, 2
ICD-O-3
NA
+∞
9.4
9
*
C184, 8148, 2
ICD-O-3
NA
+∞
9.4
9
*
C184, 8211, 2
ICD-O-3
NA
+∞
9.4
9
*
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
16.1
9.1
14
9
130
Kela drug reimbursment
Malignant tumour
2.9
8.6
54
206
JGB03
NOMESCO Finland
Partial proctectomy with partial excision of mesorectum
20.6
8.5
12
6
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
91.9
8.4
9
*
C18.00
ICD-10 Finland
Malignant tumor of the caecum without histology
13.1
8.4
14
11
JFB51
NOMESCO Finland
Other laparoscopic resection of colon
+∞
8.4
8
*
C182, 8148, 2
ICD-O-3
NA
+∞
8.4
8
*
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
8.3
62
264
L01BC06
ATC
capecitabine; oral
4.0
8.2
32
86
JN4BD
NOMESCO Finland
Extensive body CT
2.5
8.1
68
305
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.7
8.1
34
97
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.7
8.0
34
98
WX600
NOMESCO Finland
Single shot through catheter
8.0
8.0
17
22
JFA52
NOMESCO Finland
Other endoscopic haemostatic procedure in colon
18.8
7.6
11
6
C03CA01
ATC
furosemide; systemic
1.9
7.4
137
868
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
11.2
7.3
13
12
JFB30
NOMESCO Finland
Right hemicolectomy
6.9
6.9
16
24
R4110
NOMESCO Finland
Physiotherapy
1.9
6.7
123
768
8263/2-C18.4
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of transverse colon
+∞
6.3
6
*
N02BE01
ATC
paracetamol; systemic, rectal
2.1
6.2
342
3007
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
12.8
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
292
449
17.51
212.10
1.9
1.3
—
—
—
0
0
235
478
9.45
126.01
5.4
4.5
14.5
36.3
ug/l
0.64
199
408
325
1784
4.19
40.29
5.3
4.1
—
—
—
0
0
319
1747
4.04
39.25
7.0
4.9
34.0
35.0
g/l
2.36
307
1635
277
1444
3.50
35.43
2.6
2.2
—
—
—
0
0
219
1006
3.35
34.20
2.9
2.2
3.8
3.2
mg/l
1.24
189
864
160
611
3.55
33.62
2.7
2.5
2.4
2.3
g/l
2.07
152
566
249
1256
3.28
32.85
3.5
2.5
—
—
—
0
0
155
590
3.52
32.59
2.7
2.5
16.3
22.1
%
6.37
137
500
163
659
3.35
30.86
2.8
2.5
10.2
12.5
umol/l
3.65
157
608
265
1457
3.07
28.83
3.6
2.7
113.4
154.0
ug/l
2.19
244
1324
193
944
2.87
25.16
3.1
2.4
—
—
—
0
0
112
404
3.38
24.91
2.6
2.3
0.2
0.2
g/l
0.60
102
377
81
237
3.97
24.67
12.1
8.8
—
—
—
0
0
322
2119
2.96
22.74
10.1
6.7
13.9
11.9
umol/l
0.67
309
2011
124
537
2.83
19.59
1.3
1.3
—
—
—
0
0
278
1799
2.49
18.54
11.8
10.1
1.4
1.3
inr
0.38
87
498
63
192
3.66
17.87
4.2
3.7
76.1
7309.5
u/ml
0.75
56
160
120
535
2.71
17.73
10.5
6.9
0.3
1.2
mmol/l
1.29
102
434
208
1201
2.39
17.66
6.0
4.4
—
—
—
0
0
331
2355
2.66
17.51
8.1
4.9
7.1
6.8
mmol/l
1.70
324
2219
386
2983
3.48
17.32
12.6
8.1
89.2
79.9
u/l
1.67
379
2792
115
509
2.71
17.18
2.6
2.5
1.9
1.8
%
0.50
107
461
93
377
2.86
16.37
2.1
2.2
222.8
142.3
ug/g
1.04
77
303
89
354
2.90
16.22
13.2
7.9
—
—
—
0
0
92
387
2.74
15.02
3.0
2.6
73.2
70.3
e9/l
0.26
68
308
286
1988
2.26
14.58
10.7
6.9
1.2
1.2
mmol/l
3.86
246
1678
85
350
2.77
14.42
1.3
1.4
—
—
—
0
0
208
1280
2.19
14.33
3.4
3.4
56.9
105.0
e6/l
0.44
149
1000
100
451
2.58
14.14
4.0
3.0
10.4
9.3
umol/l
0.12
87
402
224
1443
2.13
13.46
4.2
3.9
114.4
77.7
e6/l
0.47
152
1062
193
1176
2.15
13.40
3.3
3.3
0.6
0.5
e6/l
0.14
138
891
85
363
2.66
13.37
2.8
2.4
36.4
33.1
u/l
0.39
73
310
128
661
2.32
13.37
4.1
3.3
0.8
0.8
mmol/l
0.98
119
621
204
1271
2.13
13.35
7.2
5.7
—
—
—
0
0
58
201
3.17
13.34
1.9
1.9
1.7
1.5
g/l
0.65
53
175
204
1277
2.12
13.13
3.3
2.5
61.2
56.5
u/l
0.58
189
1181
296
2147
2.17
12.73
13.4
9.5
4.3
4.2
e9/l
0.16
244
1899
183
1113
2.11
12.57
3.4
3.2
—
—
—
0
0
129
686
2.25
12.45
1.2
1.2
1.8
1.4
u/ml
0.26
26
187
100
484
2.38
11.99
1.2
1.3
—
—
—
0
0
420
3628
4.84
11.73
28.5
16.5
32.4
26.0
mg/l
3.67
396
2947
246
1698
2.02
11.67
7.1
5.8
0.6
0.7
%
0.34
228
1592
159
939
2.09
11.62
1.4
1.3
—
—
—
0
0
126
681
2.19
11.58
3.2
3.1
1.2
2.1
e6/l
1.00
67
387
261
1845
2.03
11.52
10.2
6.0
1.2
1.2
mmol/l
3.08
246
1660
260
1856
1.99
10.92
7.0
5.7
0.6
0.6
e9/l
0.10
213
1604
249
1754
1.97
10.84
7.4
6.2
8.9
9.0
%
0.17
232
1647
263
1888
1.98
10.83
7.4
5.8
2.2
1.9
e9/l
0.38
223
1665
248
1745
1.97
10.83
7.2
5.9
2.6
2.9
%
1.22
230
1630
324
2508
2.12
10.75
5.5
4.8
7.4
3202.7
e6/l
—
5
51
260
1867
1.97
10.61
7.0
5.7
0.0
0.0
e9/l
0.60
213
1622
251
1784
1.95
10.52
7.6
6.1
24.8
26.6
%
1.37
234
1659
248
1759
1.94
10.42
7.2
5.8
60.0
57.9
%
1.72
230
1653
234
1641
1.91
10.04
16.1
10.5
0.0
0.0
e9/l
0.44
186
1357
261
1920
1.89
9.43
7.3
5.8
0.2
0.2
e9/l
0.96
217
1692
184
1219
1.88
9.17
5.1
4.1
7.4
7.4
ph
1.25
40
234
107
590
2.08
9.10
2.6
2.0
—
—
—
0
0
323
2579
1.96
8.73
5.8
4.5
—
—
—
0
0
180
1201
1.85
8.65
4.2
3.3
—
—
—
0
0
195
1335
1.83
8.61
4.7
3.6
2.4
2.3
mmol/l
0.20
173
1150
114
656
2.00
8.57
1.8
1.4
2.7
2.8
g/l
0.04
55
389
248
1829
1.82
8.54
4.6
4.0
0.0
0.0
estimate
0.00
57
349
338
2751
2.00
8.50
4.8
4.2
16.6
13.5
mm/h
2.38
314
2511
232
1683
1.80
8.38
2.5
2.1
90.8
95.1
pmol/l
0.76
138
861
247
1832
1.80
8.22
6.6
5.3
0.0
0.0
estimate
0.00
59
352
156
1015
1.83
8.00
1.8
1.6
18.7
20.7
nmol/l
1.01
138
840
248
1860
1.77
7.78
4.8
4.0
0.0
0.0
estimate
0.00
58
342
30
103
3.05
7.00
1.5
1.8
—
—
—
0
0
93
537
1.93
6.79
6.3
5.5
1.0
1.0
mmol/l
0.12
87
493
428
3951
4.65
6.52
43.9
24.5
241.2
239.9
e9/l
0.14
416
3842
428
3953
4.62
6.47
43.9
24.4
4.3
4.5
e12/l
6.10
414
3829
428
3953
4.62
6.47
43.9
24.5
7.1
6.8
e9/l
0.87
412
3828
110
687
1.80
6.23
2.8
2.0
31.6
29.8
s
0.99
110
663
16
39
4.22
6.14
1.1
1.2
—
—
—
0
0
121
785
1.75
6.00
3.9
3.4
2.5
2.5
mmol/l
0.82
103
698
72
401
1.95
5.80
5.0
3.6
0.8
2.0
mmol/l
1.69
63
318
60
313
2.06
5.80
2.9
2.4
—
—
—
0
0
47
223
2.24
5.76
1.2
1.2
—
—
—
0
0
363
3159
1.87
5.76
34.3
17.7
37.3
39.4
%
3.18
245
2038
322
2708
1.71
5.75
4.9
4.4
—
—
—
0
0
123
823
1.69
5.38
1.8
1.8
1235.9
1202.2
nmol/l
0.12
92
624
66
366
1.95
5.38
3.4
2.7
64.3
66.4
g/l
1.49
61
326
180
1328
1.60
5.34
4.2
4.1
8.0
8.3
mg/mmol
0.05
126
857
57
301
2.03
5.33
3.2
4.3
0.6
0.5
%
0.10
18
89
399
3609
2.19
5.32
5.1
5.0
6.4
6.1
mmol/l
3.54
359
3247
62
340
1.96
5.21
5.6
4.2
1.2
1.2
mmol/l
0.01
53
299
371
3283
1.85
5.14
5.0
4.6
2.2
2.0
mu/l
0.58
334
2929
408
3736
2.34
5.06
28.4
15.9
—
—
—
0
0
61
338
1.93
4.98
3.4
4.4
0.9
0.9
%
0.03
23
122
24
89
2.79
4.93
1.9
3.0
—
—
—
0
0
123
843
1.64
4.85
3.6
2.9
554.5
567.2
mosm/kgh2o
0.28
100
720
114
767
1.66
4.83
5.1
4.8
—
—
—
0
0
126
871
1.63
4.79
3.6
3.9
—
—
—
0
0
55
299
1.96
4.74
3.3
4.6
0.0
0.1
%
0.78
19
96
168
1251
1.56
4.64
3.1
3.3
364.1
140.1
mg/l
0.33
120
833
181
1378
1.53
4.48
3.6
3.1
1466.2
1367.3
ng/l
0.13
165
1202
57
320
1.90
4.47
5.9
4.1
—
—
—
0
0
169
1270
1.54
4.43
3.2
3.2
7.6
7.7
mmol/l
0.03
146
1039
43
222
2.04
4.28
3.6
2.5
1.1
1.2
%
0.39
43
222
210
1662
1.51
4.28
4.9
3.9
26.6
38.7
ng/l
2.28
166
1277
32
148
2.25
4.20
6.6
4.0
257.0
105.0
mg/l
0.34
26
119
31
142
2.27
4.16
2.5
2.2
34.6
37.2
g/l
1.44
26
117
32
149
2.24
4.13
6.9
4.0
70.6
31.1
mg/l
0.61
26
121
55
315
1.85
4.06
3.6
4.5
0.0
0.1
%
2.85
21
111
10
24
4.24
3.90
1.0
1.0
—
—
—
0
0
42
223
1.98
3.89
2.7
2.5
—
—
—
0
0
58
344
1.79
3.83
1.6
1.5
—
—
—
0
0
25
108
2.39
3.83
6.4
4.4
—
—
—
0
0
11
30
3.74
3.66
1.4
1.7
10.7
11.2
%
0.12
11
30
18
69
2.68
3.51
3.3
2.8
4.2
4.6
e9/l
0.48
18
69
43
239
1.89
3.50
2.6
1.7
1.1
1.5
g/l
0.47
37
220
19
76
2.57
3.42
2.1
2.1
64.2
63.2
%
0.06
19
76
18
72
2.56
3.25
3.7
3.3
56.7
59.5
%
0.42
18
72
120
889
1.48
3.20
1.9
1.8
433.7
441.0
pmol/l
0.12
99
723
21
92
2.35
3.15
3.5
4.0
—
—
—
0
0
388
3596
1.69
3.10
4.5
4.9
4.3
4.5
mmol/l
3.07
356
3275
386
3575
1.67
3.06
4.5
4.8
1.4
1.4
mmol/l
0.72
347
3232
68
450
1.61
3.02
1.3
1.3
555.0
411.2
titre
0.34
16
100
300
2643
1.43
2.99
4.0
3.7
15.2
15.0
pmol/l
0.65
268
2337
119
892
1.46
2.97
2.6
2.7
4.1
4.2
e6/l
0.06
100
782
29
150
2.00
2.92
4.8
3.3
0.5
0.2
g/l
1.37
18
61
56
356
1.66
2.91
1.6
1.5
—
—
—
0
0
394
3678
1.71
2.91
5.5
5.5
2.4
2.6
mmol/l
4.08
353
3335
111
830
1.45
2.79
1.8
1.7
2.3
1.4
mg/l
0.52
89
659
131
1013
1.42
2.74
1.6
1.7
1.4
1.3
mmol/l
0.46
108
825
11
37
3.02
2.71
1.2
1.4
—
—
—
0
0
375
3473
1.55
2.69
7.3
6.5
42.6
40.7
mmol/mol
2.76
348
3188
123
944
1.42
2.68
8.9
6.9
—
—
—
0
0
12
43
2.84
2.66
1.3
1.3
—
—
—
0
0
61
407
1.58
2.62
1.5
1.6
—
—
—
0
0
48
303
1.66
2.58
3.2
2.6
10.9
10.5
g/l
0.24
42
276
373
3460
1.53
2.55
4.0
4.3
1.4
1.3
mmol/l
1.24
334
3112
37
218
1.76
2.54
1.5
1.4
—
—
—
0
0
47
297
1.65
2.52
4.0
3.8
105.4
83.1
ng/l
0.74
40
259
6
12
5.05
2.41
1.5
2.0
—
—
—
0
0
9
27
3.38
2.40
1.7
2.0
—
—
—
0
0
13
52
2.55
2.38
1.6
1.4
—
—
—
0
0
50
327
1.60
2.35
1.8
2.3
12.2
12.9
nmol/l
0.21
38
282
15
67
2.28
2.20
1.3
1.4
2.0
5.6
iu/l
—
7
19
124
987
1.36
2.13
5.5
3.7
—
—
—
0
0
11
43
2.60
2.11
1.5
1.1
—
—
—
0
0
150
1232
1.33
2.09
2.1
2.1
156.2
283.1
u/l
1.18
136
1160
23
125
1.89
2.06
1.2
1.4
220.5
281.6
ug/g
—
10
77
15
70
2.18
2.00
4.5
2.7
4.0
4.1
mmol/l
0.29
15
70
15
70
2.18
2.00
4.5
2.7
102.5
105.3
mmol/l
1.40
15
70
15
71
2.15
1.94
2.7
2.3
—
—
—
0
0
9
33
2.76
1.94
1.2
1.2
—
—
—
0
0
9
34
2.68
1.87
1.4
1.1
1.1
1.7
nmol/l
—
9
29
8
28
2.89
1.87
3.0
3.8
—
—
—
0
0
13
59
2.24
1.86
1.1
1.1
—
—
—
0
0
6
18
3.36
1.75
1.2
1.0
—
—
—
0
0
11
48
2.32
1.72
1.5
1.2
11879.0
24226.2
e6/l
—
5
25
17
90
1.92
1.67
1.5
1.7
6972.7
16694.8
e6/l
0.70
11
71
14
69
2.06
1.66
4.7
2.7
—
—
—
0
0
33
214
1.59
1.65
1.4
1.3
—
—
—
0
0
46
322
1.48
1.64
5.5
4.5
—
—
—
0
0
16
85
1.92
1.57
4.5
2.8
—
—
—
0
0
124
1031
1.28
1.52
5.3
4.3
0.0
0.0
estimate
0.50
53
339
16
86
1.89
1.52
3.6
3.0
14.3
16.2
%
—
10
47
11
51
2.19
1.51
1.5
1.2
338.2
1539.2
e6/l
—
5
33
9
37
2.46
1.48
2.2
2.3
—
—
—
0
0
62
468
1.38
1.48
2.4
1.6
—
—
—
0
0
66
504
1.36
1.47
1.8
1.4
—
—
—
0
0
5
16
3.15
1.44
5.4
4.6
57.7
49.9
%
—
5
16
126
1057
1.27
1.44
3.3
2.8
8702.9
8121.4
umol/l
0.03
108
892
10
46
2.20
1.41
1.6
2.5
—
—
—
0
0
9
40
2.28
1.41
1.1
1.4
—
—
nmol/l
—
0
0
201
1784
1.23
1.38
5.7
5.2
4.4
3.2
ug/l
0.28
174
1588
11
54
2.06
1.34
1.2
1.5
—
—
—
0
0
5
18
2.80
1.29
1.2
2.4
—
—
—
0
0
10
48
2.11
1.28
1.5
1.3
—
—
—
0
0
8
35
2.31
1.27
1.3
1.2
—
—
—
0
0
8
37
2.18
1.22
2.1
2.1
—
—
—
0
0
5
19
2.65
1.22
1.0
1.1
—
0.1
—
0
5
13
73
1.80
1.12
1.3
1.6
—
—
—
0
0
7
136
0.51
1.11
2.1
1.4
—
—
—
0
0
23
153
1.53
1.08
2.7
2.0
462.5
788.8
ug/l
0.39
23
142
39
289
1.38
1.08
5.3
3.5
7.4
7.4
ph
—
6
35
29
204
1.45
1.06
3.4
2.7
—
—
—
0
0
5
22
2.29
1.03
1.6
1.9
—
—
—
0
0
26
180
1.47
1.03
1.5
1.3
203.0
277.3
u/ml
0.34
21
167
20
132
1.54
0.99
8.8
4.6
—
—
—
0
0
5
23
2.19
0.98
2.2
1.7
—
—
—
0
0
0
29
0.00
0.98
0.0
1.4
—
—
—
0
0
118
1028
1.20
0.93
3.8
3.1
0.7
0.8
ug/l
0.30
86
703
6
28
2.16
0.92
1.2
1.7
—
—
—
0
0
6
29
2.08
0.89
1.0
1.2
—
—
—
0
0
8
43
1.88
0.87
4.0
3.4
—
—
—
0
0
6
30
2.01
0.87
1.0
1.2
—
—
—
0
0
6
31
1.95
0.84
2.2
1.3
—
—
—
0
0
10
57
1.77
0.84
2.6
4.8
—
—
—
0
0
6
32
1.89
0.82
4.5
3.3
—
—
—
0
0
31
234
1.35
0.80
3.2
3.0
0.1
0.2
e6/l
1.29
31
229
24
175
1.39
0.76
1.0
1.2
203.7
114.8
iu/ml
—
8
56
305
2906
1.16
0.74
39.9
21.8
328.5
332.1
g/l
7.81
305
2894
140
1263
1.16
0.73
5.1
4.2
—
—
—
0
0
27
203
1.35
0.72
1.3
1.3
—
—
—
0
0
18
126
1.45
0.71
6.3
3.4
—
—
—
0
0
9
142
0.63
0.71
1.2
1.4
—
—
—
0
0
9
59
1.54
0.68
1.1
1.1
—
—
—
0
0
17
119
1.45
0.68
1.8
1.6
—
—
—
0
0
5
28
1.79
0.66
3.2
4.1
—
—
—
0
0
12
79
1.53
0.63
1.1
1.2
—
—
—
0
0
13
88
1.49
0.61
1.7
1.7
—
—
—
0
0
10
151
0.65
0.60
1.2
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.6
—
—
—
0
0
11
72
1.54
0.59
1.8
3.0
—
—
—
0
0
11
73
1.52
0.56
1.5
1.2
0.8
0.8
nmol/l
0.06
11
59
8
55
1.46
0.56
1.0
1.2
—
—
—
0
0
23
177
1.32
0.56
7.0
4.2
—
—
—
0
0
27
213
1.29
0.55
5.7
3.6
—
—
—
0
0
15
108
1.40
0.53
1.0
1.1
—
—
—
0
0
9
63
1.44
0.52
1.9
1.3
—
—
—
0
0
6
100
0.59
0.52
1.8
2.4
—
—
—
0
0
16
118
1.37
0.51
1.5
1.3
0.3
0.2
g/l
1.84
16
113
12
86
1.41
0.45
1.3
2.0
211.5
236.3
pmol/l
0.46
12
81
16
122
1.32
0.43
1.1
1.2
—
—
—
0
0
6
94
0.63
0.42
1.7
1.6
—
—
—
0
0
8
57
1.41
0.42
1.6
1.5
—
—
—
0
0
39
334
1.18
0.41
1.7
1.5
—
—
—
0
0
16
123
1.31
0.41
1.5
1.3
1.2
1.2
g/l
0.42
16
118
0
17
0.00
0.40
0.0
4.1
—
35.8
—
0
12
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
9
67
1.35
0.38
1.8
1.6
—
—
—
0
0
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
27
230
1.19
0.31
7.4
3.9
—
—
—
0
0
7
52
1.35
0.31
1.6
1.6
—
—
—
0
0
7
52
1.35
0.31
1.6
1.6
—
—
—
0
0
7
52
1.35
0.31
1.6
1.6
—
—
—
0
0
7
52
1.35
0.31
1.6
1.6
—
—
—
0
0
7
53
1.33
0.31
1.6
1.2
—
—
—
0
0
10
75
1.34
0.30
2.4
2.8
—
—
—
0
0
20
168
1.20
0.27
1.5
2.1
—
—
—
0
0
14
113
1.25
0.27
1.2
1.2
—
—
—
0
0
14
113
1.25
0.27
1.4
1.9
46.8
43.5
nmol/l
0.20
14
106
5
39
1.29
0.23
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
32
287
1.12
0.21
1.7
1.4
—
—
—
0
0
5
43
1.16
0.21
1.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
10
80
1.26
0.20
1.0
1.2
—
2.7
—
0
10
15
127
1.19
0.20
1.0
1.1
—
—
—
0
0
6
50
1.20
0.20
1.7
3.1
20.6
7.2
nmol/l
—
6
50
122
1172
1.06
0.18
3.5
3.2
—
—
—
0
0
7
61
1.15
0.17
1.4
1.0
—
—
—
0
0
7
63
1.11
0.17
1.6
1.0
—
—
—
0
0
25
277
0.90
0.16
4.1
3.1
—
—
—
0
0
10
83
1.21
0.15
2.7
1.7
—
—
—
0
0
32
346
0.92
0.14
4.0
3.5
—
—
—
0
0
20
181
1.11
0.12
1.1
1.3
—
—
—
0
0
13
114
1.14
0.12
2.1
2.0
13.3
12.7
mg/l
0.10
13
105
22
201
1.10
0.11
1.2
1.4
—
52.0
—
0
13
17
186
0.91
0.09
1.3
1.5
—
—
—
0
0
7
66
1.06
0.08
1.4
1.3
—
—
—
0
0
8
78
1.03
0.07
1.0
1.2
99.4
16.6
u/l
—
8
65
26
245
1.07
0.07
3.6
3.0
5.1
3.8
e9/l
1.07
20
177
9
86
1.05
0.07
1.1
1.2
—
—
—
0
0
34
355
0.95
0.06
1.7
1.5
—
—
—
0
0
54
524
1.03
0.05
1.3
1.3
30.7
15.2
u/ml
0.34
14
188
41
396
1.04
0.05
5.9
4.6
—
—
—
0
0
58
567
1.03
0.04
1.2
1.2
18.0
39.1
iu/ml
2.05
18
166
12
123
0.97
0.00
3.8
2.5
110.8
62.7
ug/min
—
5
68
12
121
0.99
0.00
16.8
12.2
—
—
—
0
0
82
818
1.00
0.00
4.9
4.5
1.0
1.0
kg/l
0.50
13
120
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
18.6
—
0
5
8
85
0.94
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
20.7
—
0
5
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
18.3
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_COLON – Carcinoma in situ of colon

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).