autonomic nervous system disease: A disease involving the autonomic nervous system.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
865 |
4. Check minimum number of eventsNone |
865 |
5. Include endpoints |
887 |
6. Filter based on genotype QC (FinnGen only) |
860 |
Control definitions (FinnGen only)
- Control exclude
- G6_OTHNEU
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G90-G99
- Name in latin
- Morbositates systematis nervosi autonomici
Similar endpoints
↥List of similar endpoints to
Autonomic disorders
based on the number of shared cases.
Similar with more cases:
- Other neurological diseases
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6006 | 2906 | 3053 |
| Only index persons | 5139 | 2553 | 2586 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | 0.09 |
| Only index persons | 0.10 | 0.09 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 56.80 | 57.86 | 55.60 |
| Only index persons | 55.36 | 56.45 | 54.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 860 | 472 | 388 |
| Unadjusted period prevalence (%) | 0.17 | 0.17 | 0.18 |
| Median age at first event (years) | 55.85 | 54.36 | 57.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 887
- Matched controls
- 8870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G90.2
ICD-10 Finland
Horner syndrome
8157.4
307.7
445
*
G90.0
ICD-10 Finland
Idiopathic peripheral autonomic neuropathy
+∞
139.3
130
*
G90.3
ICD-10 Finland
Multi-system degeneration
+∞
108.6
102
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
26.3
94.2
66
27
G90.8
ICD-10 Finland
Other disorders of autonomic nervous system
+∞
74.0
70
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
10.5
71.8
82
85
AA1AD
NOMESCO Finland
CT of head and brain
3.6
70.6
337
1287
H02.4
ICD-10 Finland
Ptosis of eyelid
9.4
68.2
85
99
G90.9
ICD-10 Finland
Disorder of autonomic nervous system, unspecified
686.9
65.8
64
*
H57.0
ICD-10 Finland
Anomalies of pupillary function
25.1
60.5
43
18
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
7.8
58.1
84
117
M89.0
ICD-10 Finland
Algoneurodystrophy
19.6
54.7
43
23
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.6
51.5
134
327
G20
ICD-10 Finland
Parkinson disease
7.5
45.5
67
95
N03AX16
ATC
[U] pregabalin
2.9
45.4
289
1258
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
7.7
43.7
63
87
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.1
41.1
124
337
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.9
39.1
129
373
H02AA02
ATC
fludrocortisone; oral
13.9
38.4
36
27
N87
ICPC
Parkinsonism
11.3
35.7
38
35
G44.0
ICD-10 Finland
Cluster headache syndrome
11.0
35.1
38
36
R55
ICD-10 Finland
Syncope and collapse
3.3
35.0
148
502
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
33.4
463
2825
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
9.1
33.0
41
47
TAB00
NOMESCO Finland
Lumbar puncture
5.0
32.3
73
157
N06AX21
ATC
duloxetine; oral
3.1
31.9
150
541
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.7
31.7
77
176
U09.9
ICD-10 Finland
Post COVID-19 condition, unspecified
11.4
29.5
31
28
R53
ICD-10 Finland
Malaise and fatigue
2.4
28.9
258
1286
R51.80
ICD-10 Finland
Headache
2.7
28.5
183
779
N03AX12
ATC
[U] gabapentin; oral
2.6
27.3
188
828
PA6AD
NOMESCO Finland
CT of neck arteries
6.7
26.7
43
67
XCK00
NOMESCO Finland
Perimetry
3.9
26.5
83
230
I67.0
ICD-10 Finland
Dissection of cerebral arteries, nonruptured
74.7
25.9
29
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
25.1
24
*
R42
ICD-10 Finland
Dizziness and giddiness
2.3
24.3
229
1157
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.7
24.3
80
229
N28
ICPC
Limited function/disability (N)
7.9
23.9
33
43
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
23.0
22
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
235.8
22.7
23
*
N03AX09
ATC
lamotrigine; oral
4.0
22.2
65
171
G56.4
ICD-10 Finland
Causalgia
25.8
21.9
30
12
A28
ICPC
Limited function/disability NOS
2.4
21.6
169
783
N02AX02
ATC
tramadol; systemic, rectal
2.0
21.5
407
2659
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
20.7
142
618
N04BC05
ATC
pramipexole; oral
3.0
20.6
97
347
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
20.5
280
1625
N06AX16
ATC
venlafaxine; oral
2.4
20.4
154
701
M03BX01
ATC
baclofen; systemic
6.4
20.3
34
55
N03AE01
ATC
clonazepam; systemic
3.5
20.2
73
222
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
5.9
19.9
36
63
I95.1
ICD-10 Finland
Orthostatic hypotension
4.3
19.6
51
123
PA6CG
NOMESCO Finland
Extensive MRI examination of neck vasculature with high intensity magnet
47.1
19.3
23
5
N04BD01
ATC
selegiline; oral
7.4
19.2
28
39
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.0
19.1
42
88
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.6
19.0
36
66
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
18.8
18
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
18.6
85
299
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
6.3
18.2
31
51
J01MA02
ATC
ciprofloxacin; systemic
1.9
17.8
352
2294
G90.1
ICD-10 Finland
Familial dysautonomia [Riley-Day]
+∞
17.8
17
*
G90.6
ICD-10 Finland
Complex regional pain syndrome type II
+∞
17.8
17
*
G90.5
ICD-10 Finland
Complex regional pain syndrome type I
+∞
17.8
17
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
17.7
107
437
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
17.6
103
414
R4130
NOMESCO Finland
Speech therapy
4.9
17.4
39
83
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
17.3
162
806
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
15.2
17.2
28
19
Z3226
NOMESCO Finland
Physiotherapist
2.1
16.9
184
971
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
16.4
128
589
G93.3
ICD-10 Finland
Postviral fatigue syndrome
25.0
16.1
22
9
R03DC03
ATC
montelukast; oral
2.2
16.0
163
837
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
16.0
324
2112
A02BC05
ATC
esomeprazole; systemic
1.8
15.7
365
2478
G90.4
ICD-10 Finland
Autonomic dysreflexia
+∞
15.7
15
*
R13
ICD-10 Finland
Dysphagia
3.0
15.6
74
265
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.0
15.6
45
117
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
86.6
15.6
17
*
XA800
NOMESCO Finland
Neuropsychological investigation
3.6
15.6
52
150
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.0
15.1
69
242
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
14.8
207
1193
L28
ICPC
Limited function/disability (L)
2.1
14.7
159
834
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
14.7
130
630
R4110
NOMESCO Finland
Physiotherapy
1.9
14.7
257
1593
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.9
14.7
70
252
N05AH04
ATC
quetiapine; oral
2.0
14.5
174
948
N02BF02
ATC
pregabalin; oral
3.0
14.5
66
231
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.7
14.5
47
133
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.5
14.4
35
80
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
14.3
124
595
H02AB06
ATC
prednisolone; systemic
1.7
14.2
417
3002
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.6
14.2
85
345
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
14.2
148
766
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
14.1
175
965
R4120
NOMESCO Finland
Occupational therapy
2.8
14.1
73
275
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.2
14.0
128
629
WX002
NOMESCO Finland
Sedation and analgesia
2.0
13.9
182
1022
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
3.3
13.6
53
169
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
13.6
13
*
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.5
13.4
89
379
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
13.4
203
1196
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
5.7
13.4
25
45
UJF32
NOMESCO Finland
Coloscopy
1.8
13.3
231
1422
N29
ICPC
Neurological sympt/complt other
5.0
13.2
28
57
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
13.0
109
515
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
12.9
81
336
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
12.9
278
1824
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.5
12.9
87
374
N03AX11
ATC
topiramate; oral
4.2
12.9
34
83
C07AB07
ATC
bisoprolol; oral
1.7
12.6
408
2986
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
12.6
146
784
R06.0
ICD-10 Finland
Dyspnoea
1.8
12.5
242
1536
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
12.5
166
935
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.8
12.4
28
60
N05BA04
ATC
oxazepam; oral
1.8
12.4
235
1481
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
12.4
234
1473
H57.1
ICD-10 Finland
Ocular pain
3.4
12.3
44
133
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.4
12.3
88
388
CBJ41
NOMESCO Finland
Shortening of superior tarsal muscle (Müller's muscle)
38.1
12.2
15
*
A02BC02
ATC
pantoprazole; systemic
1.7
11.9
576
4648
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
11.7
173
1008
SPAT1229
SPAT
Assessment of need for aid
2.6
11.7
71
290
N06AX11
ATC
mirtazapine; oral
1.7
11.7
296
2021
M79.6
ICD-10 Finland
Pain in limb
1.7
11.6
362
2608
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
11.6
312
2164
B01AA03
ATC
warfarin; systemic
1.9
11.6
159
904
G90.7
ICD-10 Finland
Complex regional pain syndrome, other and unspecified type
+∞
11.5
11
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
121.5
11.4
12
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
121.5
11.4
12
*
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.6
11.4
37
105
ZXD05
NOMESCO Finland
Urgent procedure
1.7
11.3
275
1852
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.5
11.2
38
111
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
11.2
191
1162
N06AB10
ATC
escitalopram; oral
1.8
11.2
184
1108
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.3
11.1
28
66
G43.3
ICD-10 Finland
Complicated migraine
4.9
11.0
24
50
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.7
11.0
61
238
XF606
NOMESCO Finland
Ortostatic test
14.1
11.0
18
13
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
11.0
114
586
R52.2
ICD-10 Finland
Other chronic pain
3.2
10.8
43
139
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
10.8
218
1392
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
10.6
604
5004
M03BX02
ATC
tizanidine; oral
1.6
10.6
524
4193
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.5
10.5
36
106
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
14.4
10.5
17
12
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.1
10.5
43
142
H02AB07
ATC
prednisone; oral
2.0
10.5
127
691
A01
ICPC
Pain general/multiple sites
2.3
10.5
86
403
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
10.4
385
2870
3378X
ICD-9 Finland
Disorders of the autonomic nervous system[NEUROPATHIA AUTONOMICA PERIPHERICA ALIA DEFINITA]
+∞
10.4
10
*
K59.09
ICD-10 Finland
Constipation, unspecified
2.5
10.4
65
269
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
10.4
101
506
A06AD11
ATC
lactulose; oral
2.0
10.4
131
722
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
10.4
244
1624
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
10.4
238
1574
M48.0
ICD-10 Finland
Spinal stenosis
2.1
10.3
108
558
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.7
10.2
56
217
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
10.2
62
253
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
10.2
191
1192
JAH01
NOMESCO Finland
Laparoscopy
3.0
10.2
46
161
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
10.1
89
429
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
10.1
61
249
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.2
10.0
89
430
N06AB04
ATC
citalopram; systemic
1.8
10.0
178
1094
PA7BD
NOMESCO Finland
CT angiography of neck and brain
7.8
9.9
22
29
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
9.9
157
932
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.2
9.9
91
447
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.5
9.8
24
55
R01AD08
ATC
fluticasone; nasal
1.7
9.8
239
1601
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
8.9
9.8
20
23
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.1
9.8
41
137
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
9.7
9.8
19
20
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
9.8
70
309
X58
ICD-10 Finland
Exposure to other specified factors
1.9
9.7
128
715
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.8
9.7
50
188
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
13.6
9.7
16
12
R52.9
ICD-10 Finland
Pain, unspecified
2.1
9.7
94
471
R50.9
ICD-10 Finland
Fever, unspecified
1.9
9.6
135
771
N99
ICPC
Neurological disease other
7.2
9.5
22
31
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
9.5
91
454
Z3231
NOMESCO Finland
Registered nurse
1.7
9.4
234
1574
G23.2
ICD-10 Finland
Multiple system atrophy, parkinsonian type [MSA-P]
101.1
9.4
10
*
N02BF01
ATC
gabapentin; oral
2.3
9.4
75
347
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
9.4
9
*
G23.3
ICD-10 Finland
Multiple system atrophy, cerebellar type [MSA-C]
+∞
9.4
9
*
35800
ICD-8 Finland
Disease of peripheral autonomic nervous system, Syndroma Horner
+∞
9.4
9
*
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.4
9.4
23
53
J01FF01
ATC
clindamycin; systemic
1.7
9.3
227
1519
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
9.3
135
779
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
9.3
82
396
R25.1
ICD-10 Finland
Tremor, unspecified
3.5
9.3
31
90
G44.2
ICD-10 Finland
Tension-type headache
1.9
9.2
122
682
XF404
NOMESCO Finland
Ambulatory ECG
2.2
9.2
80
383
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
9.2
158
960
Z50.5
ICD-10 Finland
Speech therapy
5.1
9.1
19
38
N04BC04
ATC
ropinirole; oral
8.4
9.1
19
23
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
9.0
318
2327
Z2445
NOMESCO Finland
Psychologist
2.9
8.9
42
151
H02AB04
ATC
methylprednisolone; systemic
1.9
8.8
123
700
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
10.8
8.8
16
15
ZXE00
NOMESCO Finland
One hour or less
1.6
8.8
328
2426
N04BD02
ATC
rasagiline; oral
9.6
8.8
17
18
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
8.8
70
324
N18
ICPC
Paralysis/weakness
4.2
8.8
23
56
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
8.7
343
2565
C08DA01
ATC
verapamil; systemic
2.7
8.7
47
181
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
8.7
305
2224
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
8.6
270
1918
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
8.6
80
395
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.3
8.5
31
95
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
8.5
86
437
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.0
8.5
37
127
C07AA05
ATC
propranolol; systemic
1.7
8.4
174
1111
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.3
8.4
64
291
G93.0
ICD-10 Finland
Cerebral cysts
+∞
8.3
8
*
G90
ICD-10 Finland
Disorders of autonomic nervous system
+∞
8.3
8
*
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
8.3
8
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
8.3
85
434
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
8.3
127
744
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
7.2
8.3
19
27
N02AA05
ATC
oxycodone; systemic
1.8
8.2
144
878
R60.0
ICD-10 Finland
Localized oedema
1.9
8.2
102
559
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
7.6
8.2
18
24
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
3.0
8.2
35
119
G44.8
ICD-10 Finland
Other specified headache syndromes
4.8
8.1
18
38
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
4.1
8.1
22
55
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4.1
8.1
22
55
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.8
8.1
41
153
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
33.7
8.1
10
*
XLA10, ,
NOMESCO Finland
2.7
8.0
41
154
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
8.0
157
989
R20.2
ICD-10 Finland
Paraesthesia of skin
2.3
7.9
62
285
ZXA10
NOMESCO Finland
Bilateral
1.7
7.9
153
961
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
7.8
93
501
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
4.1
7.8
21
52
A02BC01
ATC
omeprazole; systemic
1.6
7.8
220
1518
N06AA09
ATC
amitriptyline; systemic
2.0
7.8
81
416
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.2
7.7
30
96
M54.3
ICD-10 Finland
Sciatica
2.4
7.7
54
236
ZXA05
NOMESCO Finland
Left side
1.6
7.7
202
1370
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
7.7
73
363
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.3
7.7
56
250
R68.88
ICD-10 Finland
Other specified general symptoms and signs, not elsewhere classified.
8.1
7.6
16
20
L01
ICPC
Neck symptom/complaint
1.8
7.6
126
756
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
9.0
7.6
15
17
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.9
7.6
22
58
R33
ICD-10 Finland
Retention of urine
2.1
7.5
69
338
R60.9
ICD-10 Finland
Oedema, unspecified
2.5
7.5
47
195
Z2446
NOMESCO Finland
Social worker
2.2
7.5
65
311
T78.4
ICD-10 Finland
Allergy, unspecified
2.6
7.5
43
171
H53.2
ICD-10 Finland
Diplopia
3.0
7.5
33
114
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
7.5
88
473
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
7.5
94
517
B01AB05
ATC
enoxaparin; parenteral
1.5
7.5
253
1820
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
7.4
144
903
J01AA02
ATC
doxycycline; systemic
1.5
7.4
640
5569
N17
ICPC
Vertigo/dizziness
1.9
7.4
100
563
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
3.2
7.3
28
89
R11
ICD-10 Finland
Nausea and vomiting
2.0
7.3
75
384
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
+∞
7.3
7
*
N05BA12
ATC
alprazolam; oral
1.9
7.2
88
478
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.7
7.2
22
60
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
7.4
7.2
16
22
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
7.2
121
728
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.5
7.2
45
187
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.1
7.2
65
317
J01DB01
ATC
cefalexin; oral
1.6
7.2
694
6163
N05CF01
ATC
zopiclone; oral
1.5
7.2
263
1922
F43.00
ICD-10 Finland
Acute stress reaction mild
3.2
7.2
27
85
AAF00
NOMESCO Finland
Ventriculostomy
30.3
7.2
9
*
Q13.2
ICD-10 Finland
Other congenital malformations of iris
30.3
7.2
9
*
M79.1
ICD-10 Finland
Myalgia
1.8
7.1
122
738
R1260
NOMESCO Finland
Evaluation of communicative skills
4.1
7.1
19
47
N02BE01
ATC
paracetamol; systemic, rectal
1.7
7.0
750
6796
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.0
129
796
A07AA02
ATC
nystatin; oral
2.3
7.0
53
240
ZXA00
NOMESCO Finland
Right side
1.6
7.0
215
1509
R32
ICD-10 Finland
Unspecified urinary incontinence
3.4
7.0
25
76
G43.9
ICD-10 Finland
Migraine, unspecified
2.3
7.0
52
234
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.0
340
2631
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.5
7.0
44
184
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
6.9
38
148
R03AC02
ATC
salbutamol; inhalant
1.5
6.9
451
3687
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
6.7
43
181
Z2221
NOMESCO Finland
Medical doctor
1.5
6.7
224
1601
R05FA02
ATC
opium derivatives and expectorants; systemic
1.5
6.7
313
2397
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
22.7
6.7
9
*
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
6.7
112
674
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
6.7
127
792
B01AC07
ATC
dipyridamole; systemic
2.9
6.6
31
111
SPAT1284
SPAT
Extensive health certificate
3.0
6.6
29
100
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.6
147
954
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
12.4
6.6
11
9
M35.7
ICD-10 Finland
Hypermobility syndrome
4.2
6.6
17
41
Z43.5
ICD-10 Finland
Attention to cystostomy
8.8
6.6
13
15
193
Kela drug reimbursment
Rasagiline
8.8
6.6
13
15
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.1
6.5
26
85
J31.0
ICD-10 Finland
Chronic rhinitis
2.0
6.5
75
401
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.8
6.4
92
527
G99.2*M50.0
ICD-10 Finland
Cervical disc disorder with myelopathy
70.3
6.4
7
*
PA6BM
NOMESCO Finland
MRI examination of neck vasculature with 3 Tesla magnet
70.3
6.4
7
*
WX402
NOMESCO Finland
General anaesthesia
1.6
6.4
166
1119
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
8.2
6.3
13
16
E0000UV, ,
ATC
1.4
6.3
330
2574
N30.9
ICD-10 Finland
Cystitis, unspecified
2.3
6.3
48
218
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
6.3
99
583
R10.0
ICD-10 Finland
Acute abdomen
2.9
6.3
29
103
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
9.3
6.3
12
13
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.1
6.3
55
265
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
6.3
40
168
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
6.3
6
*
PA7CG
NOMESCO Finland
Extended MRI examination of vessesl in brain and neck with high intensity magnet
+∞
6.3
6
*
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.2
6.2
48
220
RD210, ,
NOMESCO Finland
4.0
6.2
17
43
R01AD09
ATC
mometasone; nasal
1.4
6.2
365
2911
C08CA05
ATC
nifedipine; systemic
2.2
6.1
51
241
N05BA01
ATC
diazepam; systemic, rectal
1.7
6.1
108
659
C10AA05
ATC
atorvastatin; oral
1.4
6.1
302
2330
G04BD12
ATC
mirabegron; oral
1.8
6.1
95
559
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.5
6.1
36
146
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.9
6.1
27
94
Z02.7
ICD-10 Finland
Issue of medical certificate
2.0
6.1
61
310
XQ800
NOMESCO Finland
Prick test
2.0
6.1
61
310
L17
ICPC
Foot/toe symptom/complaint
1.5
6.1
231
1692
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
6.8
6.0
14
21
N04BC09
ATC
rotigotine; transdermal
10.1
6.0
11
11
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.0
207
1485
R52.0
ICD-10 Finland
Acute pain
2.5
6.0
35
141
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.9
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
369
1946
2.53
38.39
2.6
2.1
208.31
304.25
u/l
0.74
345
1824
481
3083
2.22
29.61
6.9
5.8
1.21
1.21
mmol/l
0.51
440
2803
504
3390
2.13
26.23
8.0
6.5
1.21
1.21
mmol/l
0.11
427
2889
205
958
2.48
26.16
2.1
1.9
29.66
29.66
s
0.00
200
924
149
622
2.68
23.86
2.4
1.9
406.88
380.51
nmol/l
0.64
139
574
496
3421
2.02
22.88
7.1
5.9
27.23
28.01
%
0.85
472
3218
489
3377
2.00
22.24
7.0
5.6
57.58
57.10
%
0.38
466
3182
559
4047
2.03
22.21
5.7
4.5
6.54
6.67
mmol/l
0.75
534
3763
452
3112
1.92
19.95
12.2
14.2
1.24
1.24
inr
0.06
122
911
32
52
6.35
19.03
1.1
1.1
0.48
1.09
nmol/l
—
6
8
425
2900
1.89
18.97
5.6
4.7
35.40
35.73
g/l
0.60
395
2699
658
5226
2.00
17.96
5.3
3.9
11.80
12.08
mm/h
0.18
625
4798
547
4089
1.88
17.93
10.0
9.0
4.31
4.10
e9/l
0.85
491
3577
31
54
5.91
17.21
1.1
1.0
—
—
—
0
0
32
64
5.15
15.35
1.2
1.1
—
—
—
0
0
180
980
2.05
15.11
2.8
2.3
2.35
2.34
g/l
0.08
172
912
33
69
4.93
15.05
1.2
1.1
—
—
—
0
0
363
2484
1.78
15.02
4.1
3.1
—
—
—
0
0
46
126
3.80
14.88
1.4
1.1
33.32
6.98
e6/l
0.53
37
93
46
126
3.80
14.88
1.4
1.2
1165.74
1617.57
e6/l
0.14
38
97
370
2557
1.77
14.72
3.9
3.4
24.06
41.89
ng/l
3.27
236
1727
189
1058
2.00
14.64
2.9
2.3
12.87
13.34
umol/l
0.38
184
981
168
905
2.06
14.46
3.0
2.4
23.09
23.18
%
0.03
149
774
47
134
3.65
14.35
1.3
1.1
3.74
3.74
mmol/l
0.01
41
125
297
1940
1.80
14.22
3.9
3.0
0.39
0.41
e6/l
0.07
228
1477
316
2105
1.78
14.14
4.1
3.1
21.00
111.15
e6/l
2.13
247
1618
22
33
6.81
14.07
1.0
1.0
1.10
1.02
u/l
—
9
21
190
1083
1.96
13.91
3.8
3.1
0.83
0.82
mmol/l
0.69
183
1021
359
2491
1.74
13.86
4.7
3.6
43.52
100.65
e6/l
1.89
261
1755
404
2904
1.72
13.68
2.6
2.2
79.55
76.42
nmol/l
1.43
366
2594
423
3079
1.71
13.68
3.6
2.7
121.96
131.49
ug/l
0.25
396
2841
235
1444
1.85
13.66
3.2
2.5
8.94
5.90
e6/l
0.35
205
1309
655
5396
1.82
13.45
9.1
7.4
78.78
78.11
u/l
0.13
619
5052
74
294
2.66
12.87
1.6
2.1
34.00
38.71
u/l
1.19
69
263
92
406
2.41
12.86
4.4
3.2
4.56
4.63
pmol/l
0.25
81
353
209
1267
1.85
12.55
4.3
3.5
62.51
407.86
ng/l
3.91
159
974
386
2790
1.68
12.45
2.3
1.9
96.78
95.23
pmol/l
0.29
211
1439
246
1581
1.77
12.12
2.0
1.6
1.85
1.06
mg/l
0.49
182
1210
262
1719
1.74
11.99
2.6
2.1
2.87
3.04
mg/l
0.55
232
1452
23
43
5.46
11.87
1.1
1.0
—
—
—
0
0
107
522
2.19
11.82
3.3
2.7
9.82
10.65
g/l
1.41
97
479
473
3636
1.64
11.77
6.6
6.3
11.18
11.35
umol/l
0.10
443
3448
200
1221
1.82
11.65
1.8
1.7
1140.03
1182.01
nmol/l
0.28
160
910
64
251
2.67
11.43
1.3
1.2
0.38
1.67
u/ml
—
5
18
569
4604
1.66
11.38
6.3
4.2
1493.70
3149.75
e6/l
—
10
64
243
1588
1.73
11.16
1.7
1.5
19.91
20.60
nmol/l
0.34
217
1340
192
1173
1.81
11.11
3.0
2.7
0.84
1.00
e6/l
0.58
119
667
179
1077
1.83
10.87
1.9
1.9
—
—
—
0
0
644
5413
1.69
10.80
4.9
3.9
14.80
14.76
pmol/l
0.19
600
4899
75
327
2.41
10.75
3.7
4.1
24.62
24.08
mmol/l
0.84
75
319
326
2324
1.64
10.67
3.2
3.4
2.34
2.35
mmol/l
1.59
284
2044
133
741
1.94
10.21
7.0
7.8
1.53
1.32
mmol/l
0.21
109
585
248
1674
1.67
9.93
2.4
2.2
—
—
—
0
0
179
1110
1.77
9.74
3.4
2.8
4.04
2.38
e6/l
0.77
105
602
132
756
1.88
9.29
1.9
1.8
—
—
—
0
0
738
6531
1.77
9.24
5.9
4.6
1.93
2.07
mu/l
0.30
688
5952
116
638
1.94
9.23
2.7
2.4
32.37
32.58
u/l
0.02
101
539
187
1191
1.72
9.22
1.4
1.3
41.90
35.54
iu/ml
0.15
54
379
303
2184
1.59
9.18
2.9
2.5
53.50
59.52
u/l
1.32
278
2012
131
753
1.87
9.11
1.9
1.8
—
—
—
0
0
804
7329
2.04
8.88
22.1
15.1
139.61
139.67
mmol/l
0.32
786
7115
805
7349
2.03
8.73
22.3
15.2
3.95
3.97
mmol/l
0.99
786
7123
178
1138
1.71
8.61
1.3
1.3
2.56
11.70
u/ml
4.56
56
448
787
7144
1.90
8.48
21.0
13.3
21.68
23.80
mg/l
1.01
665
5598
19
41
4.71
8.38
2.1
1.9
—
—
—
0
0
125
729
1.83
8.28
3.1
2.6
1.75
1.80
%
0.20
116
659
93
495
1.98
8.12
1.3
1.2
122.30
149.67
iu/ml
0.22
37
200
85
441
2.03
7.97
1.4
1.3
94.67
192.28
u/ml
2.64
75
407
40
151
2.73
7.74
1.8
2.5
17.73
16.08
%
1.89
23
82
304
2269
1.52
7.57
3.7
3.3
39.77
32.66
u/l
0.89
293
2157
51
221
2.39
7.45
1.7
2.2
137.14
626.99
ug/l
1.43
45
213
207
1429
1.59
7.29
1.7
1.5
2.08
2.41
g/l
1.84
128
867
228
1615
1.55
7.16
1.4
1.3
7.02
1.65
u/ml
1.03
59
415
107
622
1.82
7.15
4.0
3.8
2.03
1.91
mmol/l
0.13
96
509
94
530
1.87
6.92
2.5
2.9
65.76
67.13
g/l
1.00
84
485
116
698
1.76
6.90
3.6
3.2
—
—
—
0
0
33
120
2.82
6.86
1.8
1.5
95.00
113.46
u/ml
—
7
24
14
17
8.35
6.84
1.0
1.1
—
—
—
0
0
13
14
9.40
6.80
1.1
1.1
—
—
—
0
0
262
1935
1.50
6.72
2.8
2.9
831.70
1285.77
ng/l
2.04
224
1630
83
454
1.91
6.70
4.3
3.9
1.77
1.90
mmol/l
0.13
67
345
26
85
3.12
6.51
1.5
1.3
—
0.98
nmol/l
—
0
5
552
4725
1.45
6.40
3.8
3.1
47.22
48.19
u/l
0.10
506
4406
26
86
3.08
6.39
1.5
1.3
0.50
0.61
nmol/l
1.00
26
79
19
51
3.79
6.39
1.8
2.3
20.95
20.67
nmol/l
0.03
19
45
37
149
2.55
6.34
1.4
1.2
—
—
—
0
0
106
638
1.75
6.30
2.7
2.2
0.22
0.21
g/l
0.45
99
595
74
398
1.94
6.29
1.7
1.7
—
—
—
0
0
246
1820
1.49
6.18
3.0
2.5
3266.39
6931.76
umol/l
0.88
206
1599
138
898
1.64
6.13
7.1
5.5
1.04
1.05
mmol/l
0.10
131
830
35
140
2.56
6.09
1.4
1.2
247.19
240.16
u/ml
0.05
26
80
97
579
1.76
5.93
7.1
7.2
7.64
9.56
mmol/l
2.47
92
551
90
529
1.78
5.80
2.4
2.7
159.68
209.36
ng/l
0.41
79
484
46
214
2.21
5.76
1.8
1.9
—
—
—
0
0
422
3488
1.40
5.68
4.5
3.5
0.00
0.01
estimate
0.80
81
637
176
1242
1.52
5.49
3.0
3.0
2.45
2.45
mmol/l
0.27
154
1094
416
3452
1.39
5.37
4.5
3.5
0.00
0.00
estimate
0.74
85
705
131
871
1.59
5.32
2.4
2.3
100.45
124.58
ug/g
0.54
103
696
123
806
1.61
5.30
3.7
2.6
9.93
7.77
umol/l
0.43
104
699
196
1428
1.48
5.22
1.8
1.7
420.20
23789718.29
pmol/l
1.55
166
1177
414
3450
1.38
5.13
6.0
4.8
0.00
0.00
estimate
0.50
82
664
43
205
2.15
5.10
2.3
2.0
90.28
90.66
%
0.03
43
198
49
246
2.05
5.08
1.8
1.5
363.27
283.39
mu/l
0.77
44
221
79
465
1.77
5.08
1.7
1.6
—
—
—
0
0
35
154
2.33
5.02
1.8
2.2
139.00
130.44
g/l
1.29
30
112
398
3304
1.37
5.01
2.7
2.5
—
—
—
0
0
38
180
2.16
4.60
2.1
1.7
—
—
—
0
0
11
19
5.85
4.45
1.2
1.2
—
—
—
0
0
22
82
2.73
4.44
1.3
1.1
—
—
—
0
0
40
198
2.07
4.34
1.6
1.4
10.85
8.68
u/l
0.35
29
162
44
228
1.98
4.23
1.9
1.6
—
—
—
0
0
14
34
4.17
4.22
1.1
1.1
—
—
—
0
0
10
17
5.94
4.13
1.0
1.3
83.87
62.59
nmol/24h
—
10
17
727
6743
1.43
4.09
17.9
12.4
85.82
82.36
ml/min/173m2
4.11
636
5513
43
229
1.92
3.84
1.6
1.3
—
—
—
0
0
10
19
5.31
3.83
1.5
1.4
—
—
—
0
0
8
12
6.72
3.68
1.0
1.0
—
—
—
0
0
28
129
2.21
3.67
1.5
1.6
—
—
—
0
0
42
228
1.88
3.56
2.1
2.3
2.74
3.00
g/l
1.19
34
205
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
36
3.65
3.50
1.1
1.2
—
—
—
0
0
22
94
2.37
3.43
1.6
1.6
—
—
—
0
0
39
210
1.90
3.40
1.2
1.2
—
—
—
0
0
36
189
1.94
3.38
1.7
1.8
8.76
5.72
iu/l
0.38
13
55
13
42
3.13
3.38
1.2
1.1
—
—
—
0
0
36
190
1.93
3.33
1.2
1.1
—
—
—
0
0
35
183
1.95
3.33
1.8
1.5
—
—
—
0
0
84
563
1.54
3.32
3.3
3.6
1.22
1.23
mmol/l
0.80
76
481
23
102
2.29
3.31
1.3
1.2
4.38
6.70
u/ml
0.37
13
43
12
33
3.67
3.30
1.8
2.6
452.83
761.76
u/ml
1.17
12
33
37
198
1.91
3.29
1.4
1.3
—
—
—
0
0
43
243
1.81
3.24
2.0
2.3
—
—
—
0
0
43
243
1.81
3.24
2.0
2.3
3.77
3.62
g/l
0.25
34
220
43
243
1.81
3.24
2.0
2.3
6.89
7.40
g/l
1.11
35
220
24
110
2.21
3.21
1.6
1.5
—
—
—
0
0
8
15
5.37
3.19
1.1
1.1
108.88
93.27
%
—
8
15
12
35
3.46
3.11
1.6
3.0
216.17
86.29
nmol/l
0.37
12
35
63
405
1.60
3.00
1.6
1.4
—
—
—
0
0
11
31
3.58
2.99
1.7
1.2
130.85
171.58
mmol/24h
0.99
11
31
76
512
1.53
2.96
4.4
3.6
79.36
82.89
ng/l
0.11
69
447
52
320
1.66
2.94
3.1
2.4
0.56
0.65
%
2.28
52
320
32
170
1.92
2.94
1.5
1.7
—
—
—
0
0
40
229
1.78
2.92
2.1
2.3
9.79
10.77
g/l
0.70
31
205
36
200
1.83
2.89
2.3
2.2
37.18
37.99
g/l
0.25
28
177
37
209
1.80
2.83
1.1
1.2
—
—
—
0
0
13
47
2.79
2.82
2.5
2.0
—
—
—
0
0
21
97
2.19
2.78
1.0
1.1
—
—
—
0
0
7
14
5.03
2.73
3.0
2.0
17.17
15.66
umol/l
—
7
14
21
98
2.17
2.72
1.4
1.2
2.09
4.82
u/ml
0.50
11
28
42
251
1.71
2.67
2.2
2.2
1886.01
2395.73
u/l
—
10
98
78
541
1.48
2.66
2.4
2.4
5.63
7.08
ug/l
0.38
63
479
31
169
1.86
2.66
1.5
1.7
—
—
—
0
0
11
35
3.17
2.65
1.1
1.1
—
—
—
0
0
26
134
1.97
2.62
1.6
1.2
—
—
—
0
0
26
134
1.97
2.62
1.6
1.2
—
—
—
0
0
34
192
1.80
2.62
2.3
2.3
0.00
0.03
g/l
0.50
28
178
7
15
4.69
2.60
2.6
1.7
—
—
—
0
0
238
1981
1.28
2.58
3.2
3.3
604.18
215.80
mg/l
0.48
154
1289
50
317
1.61
2.55
1.5
1.4
22.96
24.94
iu/l
0.20
40
272
39
232
1.71
2.53
1.5
1.6
0.51
27.36
iu/ml
—
8
44
18
82
2.22
2.48
1.9
2.3
27.60
25.82
mg/l
—
5
21
15
63
2.40
2.47
9.3
5.2
81.97
34.18
u/ml
—
7
18
8
21
3.83
2.46
1.1
1.1
—
—
—
0
0
8
21
3.83
2.46
1.1
1.1
—
—
—
0
0
40
242
1.68
2.45
2.4
2.8
—
—
—
0
0
257
2171
1.26
2.45
3.2
3.2
7.75
7.77
mmol/l
0.02
210
1835
36
212
1.73
2.43
2.2
2.6
0.20
1.16
g/l
2.05
28
189
15
64
2.37
2.39
2.7
2.2
—
—
—
0
0
32
184
1.77
2.35
2.3
2.3
0.00
0.00
g/l
-0.00
26
170
28
155
1.83
2.32
1.7
1.4
—
—
—
0
0
18
85
2.14
2.30
1.4
1.3
—
—
—
0
0
42
647
0.63
2.25
1.9
1.7
—
—
—
0
0
34
203
1.70
2.20
1.4
1.4
332.19
305.53
ug/g
0.25
16
120
115
886
1.34
2.19
1.9
1.8
1.62
1.45
%
1.05
100
798
56
379
1.51
2.19
1.0
1.0
—
—
—
0
0
47
306
1.57
2.18
5.3
4.4
24.81
24.99
mmol/l
0.15
47
290
7
19
3.70
2.15
1.0
1.3
—
—
—
0
0
7
19
3.70
2.15
1.0
1.2
—
—
—
0
0
6
14
4.31
2.15
1.3
1.1
0.97
2.39
mmol/l
—
6
14
11
42
2.64
2.14
1.2
1.2
—
—
—
0
0
31
182
1.73
2.14
2.4
2.3
0.00
0.00
g/l
-0.00
26
169
665
6271
1.24
2.08
24.7
16.0
14.76
14.81
%
0.09
658
6158
5
10
5.02
2.07
1.0
1.5
—
—
—
0
0
28
162
1.75
2.04
1.3
1.7
—
—
—
0
0
686
6496
1.25
2.04
6.1
5.5
39.65
39.62
mmol/mol
0.02
643
6010
25
140
1.81
2.02
1.5
1.6
—
—
—
0
0
19
347
0.54
1.97
1.4
1.5
—
—
—
0
0
18
91
2.00
1.96
1.0
1.1
110.06
117.79
%
0.41
18
84
160
1311
1.27
1.95
1.6
1.5
—
—
—
0
0
5
11
4.56
1.94
1.4
1.0
—
—
—
0
0
5
11
4.56
1.94
1.0
1.1
—
—
—
0
0
8
27
2.98
1.94
1.0
1.0
1356.13
1679.96
miu/ml
—
8
27
19
99
1.94
1.91
1.6
1.7
—
—
—
0
0
24
136
1.79
1.89
1.1
1.1
0.52
2.25
u/ml
1.51
14
70
7
22
3.20
1.88
1.6
2.0
108.57
78.81
ug/l
—
7
22
33
207
1.62
1.82
1.1
1.1
20.02
5.10
u/ml
—
5
25
21
116
1.83
1.79
1.0
1.1
0.18
2.16
u/ml
2.52
11
59
11
47
2.36
1.78
1.9
1.6
—
—
—
0
0
50
347
1.47
1.77
2.0
1.9
—
—
—
0
0
303
2682
1.20
1.76
5.0
3.7
—
—
—
0
0
6
18
3.35
1.75
1.0
1.2
—
—
—
0
0
6
18
3.35
1.75
1.0
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
31
194
1.62
1.73
3.1
2.8
0.34
0.35
u/ml
0.07
16
106
37
242
1.55
1.73
1.7
1.7
—
—
—
0
0
8
30
2.68
1.72
1.1
1.2
—
—
—
0
0
216
1855
1.22
1.72
5.5
3.8
0.00
0.01
estimate
0.69
79
646
241
2093
1.21
1.71
3.9
3.9
12.59
9.13
mg/mmol
0.36
151
1341
14
68
2.08
1.71
2.7
2.3
—
—
—
0
0
12
55
2.20
1.68
1.8
1.8
—
—
—
0
0
790
7649
1.30
1.67
13.3
9.9
26.25
26.53
u/l
0.14
764
7361
181
1532
1.23
1.66
5.2
3.7
1.02
1.02
kg/l
0.12
27
209
6
19
3.17
1.66
1.0
1.3
—
—
—
0
0
16
83
1.94
1.65
1.2
1.6
—
—
—
0
0
16
83
1.94
1.65
1.2
1.6
—
—
—
0
0
14
69
2.05
1.65
1.2
2.0
—
—
—
0
0
15
76
1.99
1.65
1.1
1.9
—
—
—
0
0
105
838
1.29
1.60
8.7
6.5
—
—
—
0
0
19
106
1.81
1.59
1.1
1.0
1.63
1.57
u/ml
—
7
43
27
168
1.63
1.56
1.2
1.2
—
—
—
0
0
21
122
1.74
1.55
1.5
1.9
—
—
—
0
0
10
205
0.48
1.52
1.2
1.5
—
—
—
0
0
7
27
2.60
1.51
3.6
5.1
—
—
—
0
0
60
445
1.37
1.51
2.2
1.9
—
—
—
0
0
6
21
2.87
1.50
4.7
2.0
—
—
—
0
0
20
116
1.74
1.49
1.3
1.7
—
—
—
0
0
20
116
1.74
1.49
1.3
1.7
—
—
—
0
0
12
58
2.08
1.49
1.0
1.4
—
—
—
0
0
9
38
2.38
1.46
1.3
1.6
—
—
—
0
0
9
38
2.38
1.46
1.3
1.6
—
—
—
0
0
5
16
3.14
1.44
1.0
1.4
—
—
—
0
0
70
537
1.33
1.43
2.6
2.1
16.67
12.97
nmol/l
0.76
63
480
18
103
1.76
1.41
1.7
1.6
—
—
—
0
0
496
4639
1.16
1.37
3.5
3.1
—
—
—
0
0
23
143
1.62
1.36
8.1
9.4
104.74
105.53
mmol/l
0.27
23
129
10
193
0.51
1.30
1.1
1.4
—
—
—
0
0
10
193
0.51
1.30
1.1
1.4
—
—
—
0
0
19
114
1.68
1.29
1.1
1.1
—
—
—
0
0
10
192
0.52
1.29
1.1
1.4
—
—
—
0
0
10
192
0.52
1.29
1.1
1.4
—
—
—
0
0
17
99
1.73
1.28
1.0
1.0
0.37
3.93
u/ml
2.04
11
45
8
35
2.30
1.27
1.1
1.9
—
—
—
0
0
37
262
1.43
1.24
1.9
1.9
—
—
—
0
0
6
25
2.41
1.24
1.8
1.4
—
—
—
0
0
6
25
2.41
1.24
1.8
1.4
—
—
—
0
0
10
49
2.05
1.22
1.4
1.3
—
—
—
0
0
8
37
2.17
1.21
2.4
1.8
—
—
—
0
0
14
78
1.81
1.21
1.7
1.9
—
—
—
0
0
8
38
2.12
1.18
2.4
1.7
—
—
—
0
0
16
94
1.72
1.18
10.2
5.9
11.59
11.47
mg/l
0.04
16
86
8
39
2.06
1.15
1.3
1.1
—
—
—
0
0
0
36
0.00
1.14
0.0
1.4
—
—
—
0
0
250
2250
1.15
1.14
4.4
4.8
2.23
2.97
ug/l
0.82
219
2009
49
371
1.34
1.13
1.5
1.3
—
—
—
0
0
713
6894
1.17
1.12
4.8
4.4
5.93
5.93
mmol/l
0.01
653
6266
7
30
2.34
1.12
1.3
1.3
0.29
0.27
g/l
—
7
25
8
41
1.96
1.09
1.0
1.0
—
—
—
0
0
7
32
2.20
1.08
1.3
1.3
—
53.33
—
0
6
13
74
1.77
1.07
1.2
1.2
2300.14
1292.29
e6/l
—
7
52
10
52
1.93
1.06
1.5
1.3
—
—
—
0
0
9
46
1.97
1.03
2.2
1.7
—
—
—
0
0
66
529
1.27
1.03
2.9
2.7
63.38
66.13
ml/min/173m2
0.27
29
218
18
114
1.59
1.03
2.2
3.3
—
710.56
—
0
9
10
53
1.90
1.01
1.5
1.3
—
—
—
0
0
26
181
1.45
0.99
1.6
1.2
1.42
6.33
u/ml
—
5
28
84
697
1.23
0.98
3.1
4.3
2.84
24.71
ug/l
1.23
65
574
12
69
1.75
0.96
1.3
1.2
38827.83
41656.57
e6/l
—
6
42
91
764
1.21
0.95
2.5
2.0
—
—
—
0
0
26
183
1.43
0.94
1.2
1.3
—
—
—
0
0
6
27
2.23
0.93
2.8
2.2
—
—
—
0
0
10
55
1.83
0.92
1.2
1.1
—
—
—
0
0
10
55
1.83
0.92
1.2
1.1
—
—
—
0
0
10
55
1.83
0.92
1.2
1.1
—
—
—
0
0
6
28
2.15
0.91
2.3
2.8
36933.33
37664.46
ug/l
—
6
28
6
29
2.08
0.89
1.0
1.0
—
—
—
0
0
99
846
1.19
0.87
2.6
2.0
—
—
—
0
0
8
43
1.87
0.87
1.6
1.4
9.13
14.61
u/l
—
8
38
21
145
1.46
0.85
1.5
1.2
28.70
12.93
u/ml
—
5
10
15
227
0.65
0.85
1.3
1.5
—
—
—
0
0
199
1801
1.14
0.84
3.8
4.1
23.30
21.24
%
0.93
87
843
817
8033
1.22
0.83
30.2
19.6
39.90
40.22
%
0.81
764
7520
817
8036
1.21
0.81
30.1
19.5
251.44
250.16
e9/l
0.22
802
7810
7
122
0.57
0.78
1.7
1.6
—
—
—
0
0
817
8041
1.20
0.77
30.0
19.5
4.45
4.51
e12/l
2.65
798
7797
12
75
1.61
0.75
1.7
1.5
19.50
18.94
ug/l
0.03
12
75
9
54
1.67
0.74
1.2
1.1
—
—
—
0
0
9
54
1.67
0.74
1.2
1.1
—
—
—
0
0
817
8044
1.20
0.74
30.2
19.6
133.82
135.68
g/l
3.04
806
7910
9
55
1.64
0.73
1.2
1.1
—
65.17
—
0
6
100
872
1.17
0.72
5.1
4.2
32.44
31.76
%
0.26
72
576
19
134
1.43
0.71
3.3
3.9
58.58
56.95
%
0.26
19
134
9
59
1.53
0.68
1.2
1.2
—
—
—
0
0
7
43
1.63
0.67
1.6
1.8
—
—
—
0
0
35
278
1.27
0.64
5.9
6.4
1.71
1.57
%
0.64
35
262
16
112
1.44
0.63
1.1
1.3
—
—
—
0
0
18
129
1.40
0.63
3.1
3.5
4.08
4.22
e9/l
0.13
18
129
126
1130
1.13
0.63
1.5
1.4
—
—
—
0
0
11
162
0.67
0.59
1.4
1.6
—
—
—
0
0
8
53
1.51
0.58
4.9
2.3
—
—
—
0
0
8
55
1.46
0.56
1.0
1.3
—
—
—
0
0
6
37
1.63
0.55
1.3
1.3
—
—
—
0
0
6
37
1.63
0.55
1.3
1.3
—
—
—
0
0
6
39
1.54
0.53
1.5
1.2
—
—
—
0
0
31
251
1.24
0.51
1.4
1.9
—
—
—
0
0
7
46
1.53
0.48
2.4
1.8
—
—
—
0
0
7
47
1.49
0.47
1.7
1.3
—
—
—
0
0
27
219
1.24
0.45
1.6
1.4
—
—
—
0
0
10
140
0.71
0.43
1.8
1.7
—
—
—
0
0
5
31
1.62
0.43
1.6
1.6
—
—
—
0
0
5
33
1.52
0.41
1.4
1.2
—
—
—
0
0
5
33
1.52
0.41
1.4
1.2
—
—
—
0
0
22
177
1.25
0.40
1.5
2.2
84.37
84.74
ug/min
0.00
15
99
9
66
1.37
0.38
1.9
1.8
—
—
—
0
0
9
69
1.31
0.37
5.8
4.0
—
—
—
0
0
6
44
1.37
0.34
1.3
1.2
10.00
11.29
u/l
—
6
38
33
284
1.17
0.33
1.6
1.7
4.31
3.34
mg/l
0.24
26
219
6
89
0.67
0.33
3.0
2.0
12.35
13.09
%
—
6
89
6
47
1.28
0.32
1.3
1.4
160.32
163.75
pmol/l
—
6
47
31
358
0.86
0.31
4.0
3.0
17.93
58.78
u/ml
2.05
31
344
7
52
1.35
0.31
1.3
1.5
7.00
7.61
u/l
—
7
46
7
55
1.27
0.30
1.1
1.1
331.00
280.85
mg/l
—
7
47
12
152
0.79
0.29
5.0
3.8
17.56
23.99
mg/l
—
7
97
8
62
1.29
0.28
1.3
1.7
—
—
—
0
0
8
62
1.29
0.28
1.3
1.7
—
—
—
0
0
8
62
1.29
0.28
1.3
1.7
—
—
—
0
0
199
1906
1.06
0.27
1.7
1.7
1.36
1.38
mmol/l
0.10
171
1608
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
0.50
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
694
7004
0.96
0.19
4.8
4.2
1.44
1.46
mmol/l
0.34
633
6441
12
100
1.20
0.18
1.1
1.1
—
—
—
0
0
8
69
1.16
0.16
1.3
1.3
—
—
—
0
0
137
1320
1.04
0.16
2.8
2.9
0.68
0.75
ug/l
0.42
84
855
11
92
1.20
0.16
1.5
1.6
—
—
—
0
0
9
78
1.16
0.15
1.0
1.2
74.33
49.95
u/l
—
9
72
19
169
1.13
0.14
1.4
1.8
28416.69
13004.01
e6/l
0.34
13
124
11
93
1.19
0.14
1.5
1.4
—
—
—
0
0
7
90
0.78
0.14
1.9
1.3
—
—
—
0
0
8
97
0.82
0.13
1.3
1.0
—
—
—
0
0
8
99
0.81
0.13
1.3
1.4
5.11
7.31
mmol/l
—
8
84
11
128
0.86
0.13
1.1
1.2
74.74
24.08
u/l
0.49
11
111
25
228
1.10
0.13
1.7
1.4
—
—
—
0
0
9
107
0.84
0.13
1.2
1.1
—
—
—
0
0
701
7045
0.98
0.09
4.8
4.3
4.58
4.67
mmol/l
1.37
644
6514
713
7163
0.98
0.08
5.3
4.7
2.71
2.77
mmol/l
1.10
657
6588
6
57
1.05
0.08
1.7
2.3
595.67
597.88
ml
—
6
34
13
117
1.11
0.08
1.2
1.7
—
—
—
0
0
7
67
1.05
0.08
1.0
1.0
—
—
—
0
0
17
158
1.08
0.06
1.4
1.3
—
—
—
0
0
25
240
1.04
0.03
1.1
1.3
172.90
245.10
miu/ml
—
7
127
676
6747
1.01
0.02
4.3
3.8
1.30
1.30
mmol/l
0.04
618
6157
10
93
1.08
0.02
1.5
1.4
—
—
—
0
0
10
94
1.06
0.01
1.5
1.4
—
—
—
0
0
10
94
1.06
0.01
1.5
1.4
—
—
—
0
0
10
94
1.06
0.01
1.0
1.1
1.61
1.50
g/l
—
10
85
19
186
1.02
0.00
1.4
1.5
—
—
—
0
0
10
95
1.05
0.00
1.5
1.4
—
—
—
0
0
10
95
1.05
0.00
1.5
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
5
59
0.85
-0.00
2.2
1.5
85.00
81.03
umol/l
—
5
59
0
8
0.00
-0.00
0.0
5.3
—
7.58
—
0
8
9
98
0.92
-0.00
2.4
2.5
106.78
105.45
mmol/l
—
9
98
Mortality – FinRegistry
↥Association
Association between endpoint G6_AUTONOM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_AUTONOM | 2.775 [2.37, 3.25] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.162 |
During the follow-up period (1.1.1998 — 31.12.2019), 671 out of 2348 females with G6_AUTONOM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_AUTONOM | 2.517 [2.17, 2.92] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 798 out of 2520 males with G6_AUTONOM died.
Mortality risk
Mortality risk for people of age
years, who have G6_AUTONOM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.269% | 0.529% |
| 5 | 1.548% | 2.991% |
| 10 | 3.906% | 7.184% |
| 15 | 7.323% | 13.304% |
| 20 | 12.638% | 22.103% |
Relationships between endpoints
↥Index endpoint: G6_AUTONOM – Autonomic disorders
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data